@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo1068: (2016-03-21 )
MKKWMVIISIISLVALLGACGNNDNEKDQEDKSTTDSTTKKAKSSSNESNKAAETKENDTNDKAATTDKGSSNPTKEEKDTSTTTDTPKKETPKSPAKTEAFSFSPSGFKVSTVESILGGDVTTTYLSSSKSFQKDFEALTLFINQYKVEHVINPTKEVSASNPESYLANKNGYVITLDISIKNNSKKDKMYKADQISLLGASKSVGGSLDNFIPSGFHLIGSSSDPYNFTAGKTARGLLTFTMDEATYNDLAKDSQIGVPDPSRFDSSSTKGSSQDNVVAPFPIK
Atome Classification :
(20 SA)
-----.........10-----.........20........30........40...--.....50........60........70........80....---------....90........100...---....110-...-......120.......130.......140..---....-.150..--.-------------....160.-----------------......170...------....------180..--...-..190...--..---.-..200------.......210-.......220-..-......230.......240..-.....250.......260.......270.........280....--------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-----MK
K
W
M
V
I
I
S
I
------
I
S
L
V
A
L
L
G
ACGNNDNEKDQEDKSTTDSTTKKAKS--SSNESNKAAETKENDTNDKAATTDKGSSNPTKEEKDTSTTT---------DTPKKETPKSPAKTE
A
F
SFS---PSG
F
K
---
V
S
T
-
V
E
S
I
LGGD
V
T
T
T
YLSS
S
K
S
F
Q
K
D
F
E
A
L
T
L
F
I
---
N
Q
Y
K
-
V
E
H
VIN--P-------------
T
K
EVSASN-----------------P
E
S
YLANKN
G
Y
V
------
I
T
L
D
------
I
S
IKN--NSK-KDKM-YKA--D
Q
---
I
-
S
L
LGA------SKSVGG
S
L
D
N
-FIPS
G
F
H
L
I--GS-SSDPYNFTAGKTA
R
G
L
L
T
F
T
M-DEA
T
Y
N
DLAKDSQIGVPDPSRFDSSS--TKGSSQDNVVAPFPIK--------------------------------------
49
Fugue
96.40
98%
-89
- C7 -
4EAE
2
?
A:
[4-190]
-------------------------------------------------------------------------------------------------------------------------
E
A
F
S
F
S
---
P
S
G
F
K
---
V
S
T
-
V
E
S
I
L
G
G
D
V
T
T
T
Y
L
S
S
S
K
S
F
Q
K
D
F
E
A
L
T
L
F
I
---
N
Q
Y
K
-
V
E
H
V
I
N
--
P
-------------
T
K
E
V
S
A
S
N
-----------------
P
E
S
Y
L
A
N
K
N
G
Y
V
------
I
T
L
D
------
I
S
I
K
N
--
N
S
K
-
K
D
-
K
M
Y
K
A
--
D
Q
---
I
-
S
L
L
G
A
------
S
K
S
V
G
G
S
L
D
N
-
F
I
P
S
G
F
H
L
I
--
G
S
-
S
S
D
P
Y
N
F
T
A
G
K
T
A
R
G
L
L
T
F
-
T
M
D
E
A
T
Y
N
D
L
A
K
D
S
Q
I
G
V
P
D
P
S
R
F
D
S
-----
S
G
S
S
Q
D
N
V
V
A
P
F
P
I
K
--------------------------------------
6
PsiBlast_CBE
96.13
98%
-81
- C7 -
4EAE
3
?
B:
[4-190]
-------------------------------------------------------------------------------------------------------------------------
E
A
F
S
F
S
---
P
S
G
F
K
---
V
S
T
-
V
E
S
I
L
G
G
D
V
T
T
T
Y
L
S
S
S
K
S
F
Q
K
D
F
E
A
L
T
L
F
I
---
N
Q
Y
K
-
V
E
H
V
I
N
--
P
-------------
T
K
E
V
S
A
S
N
-----------------
P
E
S
Y
L
A
N
K
N
G
Y
V
------
I
T
L
D
------
I
S
I
K
N
--
N
S
K
-
K
D
K
M
-
Y
K
A
--
D
Q
---
I
-
S
L
L
G
A
------
S
K
S
V
G
G
S
L
D
N
-
F
I
P
S
G
F
H
L
I
--
G
S
-
S
S
D
P
Y
N
F
T
A
G
K
T
A
R
G
L
L
T
F
T
M
-
D
E
A
T
Y
N
D
L
A
K
D
S
Q
I
G
V
P
D
P
S
R
F
D
S
S
S
--
T
K
G
S
S
Q
D
N
V
V
A
P
F
P
I
K
--------------------------------------
1
PsiBlast_PDB
95.77
98%
-85
- C7 -
4EAE
2
?
A:
[4-190]
-------------------------------------------------------------------------------------------------------------------------
E
A
F
S
F
S
---
P
S
G
F
K
---
V
S
T
-
V
E
S
I
L
G
G
D
V
T
T
T
Y
L
S
S
S
K
S
F
Q
K
D
F
E
A
L
T
L
F
I
---
N
Q
Y
K
-
V
E
H
V
I
N
--
P
-------------
T
K
E
V
S
A
S
N
-----------------
P
E
S
Y
L
A
N
K
N
G
Y
V
------
I
T
L
D
------
I
S
I
K
N
--
N
S
K
-
K
D
K
M
-
Y
K
A
--
D
Q
---
I
-
S
L
L
G
A
------
S
K
S
V
G
G
S
L
D
N
-
F
I
P
S
G
F
H
L
I
--
G
S
-
S
S
D
P
Y
N
F
T
A
G
K
T
A
R
G
L
L
T
F
T
M
-
D
E
A
T
Y
N
D
L
A
K
D
S
Q
I
G
V
P
D
P
S
R
F
D
S
S
-----
G
S
S
Q
D
N
V
V
A
P
F
P
I
K
--------------------------------------
52
Fugue
57.77
18%
29
- C6 -
4P4M
5
?
A:
[92-378]
------
K
P
K
L
K
A
I
Q
E
------
L
T
Q
V
H
G
F
G
P
-
R
A
A
A
A
L
F
D
R
E
G
I
F
T
V
D
E
L
L
Q
K
A
D
S
IP
S
L
T
D
Q
Q
R
V
G
I
K
Y
F
Y
D
I
N
E
K
---------
I
P
M
Q
E
S
V
L
H
E
N
Y
L
---------
R
E
K
C
M
E
V
L
G
K
D
F
S
I
L
I
C
G
S
Y
---
R
R
R
H
P
---
F
S
G
D
V
D
A
I
L
S
R
T
L
D
A
P
P
L
S
E
P
V
A
A
T
G
V
L
G
H
F
V
E
F
L
---
E
S
L
K
Y
L
E
A
T
M
A
QG
P
-------------
L
K
Y
M
G
M
G
R
-----------------
L
P
P
R
I
N
T
K
V
Y
K
A
------
R
R
V
D
------
I
R
L
I
E
-------
T
K
S
-
V
P
T
--
A
M
---
L
-
T
F
T
G
S
------
K
N
F
N
V
I
M
R
Q
A
-
A
I
S
K
G
Y
L
L
--------
N
E
Y
---------
G
L
F
K
L
G
T
-
P
E
E
A
R
G
K
-
N
A
G
E
E
L
G
V
P
-
K
D
E
L
E
D
K
R
--
V
E
V
R
S
E
Q
D
V
F
D
V
L
G
M
P
YAKPENRDP-----------------------------
58
Fugue
55.09
13%
-13
- C2 -
3J4Q
-
KAP2_MOUSE
B:
[9-394]
G
L
T
E
L
L
Q
G
Y
T
V
E
V
L
R
------
Q
Q
P
P
D
L
V
D
F
A
V
E
Y
F
T
R
L
R
E
A
R
R
Q
E
S
D
T
F
I
V
S
P
T
T
--
F
H
T
Q
E
S
S
A
V
P
V
I
E
E
D
G
E
S
D
S
D
S
E
D
A
D
L
E
V
P
V
P
S
K
F
T
R
R
V
S
V
CAETFNPDE
E
E
E
D
V
V
H
P
K
T
D
E
Q
R
C
R
L
Q
E
A
C
KD
I
L
L
F
K
NLD
Q
E
Q
-
L
S
Q
V
L
D
A
M
F
E
K
I
V
K
T
D
E
H
V
I
D
Q
G
D
D
G
D
N
F
Y
V
I
E
R
G
T
Y
D
-
I
L
V
T
K
D
--
N
-------------
Q
T
R
S
V
G
Q
Y
D
NRGSFG
E
L
A
L
M
YNTPR
A
A
T
I
I
A
T
S
E
G
S
L
------
W
G
L
D
R
V
T
F
R
R
I
I
V
K
N
--
N
A
K
-
K
R
K
M
-
F
E
S
F
I
E
S
---
V
-
P
L
F
K
S
LE
M
S
E
R
M
K
I
V
D
V
I
G
E
K
-
I
Y
K
D
G
E
R
I
I
A
Q
G
E
-
K
A
D
S
F
Y
I
I
E
S
G
E
V
S
I
L
I
R
S
K
T
-
K
S
N
K
N
G
G
N
Q
E
V
E
I
A
H
C
H
K
G
Q
Y
F
G
E
L
A
L
V
T
N
K
P
R
A
A
S
A
Y
A
V
G
D
V
K
C
L
V
M
D
V
Q
A
F
E
R
L
LGP
C
M
D
I
M
K
R
NISH
Y
E
E
Q
L
V
K
M
FGSN
51
Fugue
47.94
14%
17
- C6 -
2HZM
-
MED18_YEAST
B:
[1-312]
-----
V
Q
Q
L
S
L
F
G
S
I
G
DDG
Y
D
L
L
I
S
T
L
T
T
I
S
G
N
P
--
P
L
L
Y
N
S
L
C
T
V
W
K
P
N
P
S
Y
D
V
--
E
P
N
R
I
K
L
S
K
E
V
P
F
S
Y
L
I
D
E
K
P
L
N
F
R
I
L
K
S
F
E
S
C
S
P
W
S
L
Q
I
S
---------
D
I
R
S
V
S
M
Q
T
I
A
E
T
I
I
L
S
S
A
G
---
K
N
S
S
V
---
S
S
L
-
M
N
G
-
L
G
Y
V
F
E
F
Q
Y
L
T
I
G
V
K
F
F
M
---
K
H
G
L
I
L
---
E
L
Q
K
-
I
W
Q
I
E
E
--
A
-------------
G
N
S
Q
I
T
S
G
--------------------------
G
F
L
------
L
K
A
Y
------
I
N
V
S
R
--
G
T
D
-
I
D
R
I
-
N
Y
T
--
E
T
-----
V
L
M
N
L
------
K
K
E
L
Q
G
Y
I
E
---------------------------------------------------
L
S
V
P
D
R
Q
S
M
D
S
R
V
--
A
H
G
---
N
I
L
I
A
A
A
L
E
H
--------------------------------------
54
Fugue
46.59
13%
-7
* C7 *
2CUA
2
COX2_THETH
B:
[1-135]
--------------------------------------------------------------------
A
Y
T
L
A
T
H
T
A
G
A
G
K
L
E
R
V
D
P
T
T
V
R
Q
E
G
P
W
A
D
---------
P
A
Q
A
V
V
Q
T
G
P
N
Q
Y
T
V
Y
V
L
A
F
---
A
F
G
Y
Q
---
P
N
P
-
I
E
V
P
Q
G
A
E
I
V
F
K
I
T
S
P
D
V
I
-------
H
G
F
H
V
---
E
G
T
N
-
I
N
V
E
V
L
--
P
G
E
V
S
---------
T
V
R
Y
T
F
K
R
-----------------
P
G
E
Y
R
I
I
C
N
Q
Y
C
GLGHQN
M
F
G
T
------
I
V
V
K
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
45.05
7%
-21
- C7 -
2LLG
-
?
A:
[16-127]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
L
L
V
P
D
G
R
L
A
L
---
T
A
L
H
-
K
G
K
--
D
-----------------------------------------------
Y
Q
G
K
P
M
------
F
Y
V
L
------
F
E
L
T
N
--
T
T
E
-
K
T
Q
N
-
I
Q
L
--
M
I
Q
S
-
F
M
E
V
S
Q
T
------
V
H
G
K
A
Q
N
L
Q
Y
A
V
L
T
D
S
-
P
F
Q
--
D
K
L
D
R
L
A
D
E
I
N
P
G
E
T
I
Q
G
A
Y
P
Y
E
F
-
I
N
E
N
----
K
P
V
-
H
F
K
F
R
D
R
---------------------------------------------------------------
10
HHSearch
44.53
13%
4
- C7 -
3QFG
-
?
A:
[65-176]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
S
D
K
F
E
A
K
I
---
K
E
P
F
-
I
I
N
E
K
------------------------------------------------
D
E
K
K
K
Y
------
I
A
F
K
------
M
E
I
T
A
--
K
K
D
D
K
D
L
N
-
P
S
S
--
I
S
H
D
Y
I
-
N
I
T
Q
D
------
D
K
N
T
V
N
K
L
R
D
G
Y
L
L
S
D
K
K
Y
K
--
D
W
T
E
H
N
Q
D
Q
I
K
K
G
K
T
A
Q
A
M
F
I
Y
E
L
-
R
G
D
-----
G
N
I
-
N
L
N
V
H
K
Y
---------------------------------------------------------------
7
HHSearch
42.66
11%
-46
- C7 -
3NRF
1
?
A:
[21-102]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
G
D
K
H
F
R
T
------
Q
A
F
K
------
V
R
L
V
N
--
A
A
K
-
S
E
I
S
-
L
K
N
--
S
C
---
L
-
V
A
Q
S
---------
A
A
G
Q
S
F
R
L
-
D
T
V
D
E
E
L
T
A
--
D
-------
T
L
K
P
G
A
S
V
E
G
D
A
I
F
A
S
-
E
D
D
A
V
Y
G
A
S
L
V
-
R
L
S
-------------------------------------------------------------------
56
Fugue
42.34
22%
144
* C6 *
2BEQ
-
SPIKE_CVHSA
A:
[914-949]
------------------------------------
S
Q
I
Q
E
S
L
T
T
T
S
T
A
L
G
K
L
Q
D
--
V
V
N
Q
N
A
Q
A
L
N
T
L
V
K
Q
L
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
57
Fugue
41.52
8%
120
- C6 -
4WY4
-
SNP29_HUMAN
C:
[1-78]
----------------------------------
A
D
R
Q
Q
Y
L
R
Q
E
V
L
R
R
A
E
A
T
A
A
S
--
T
S
R
S
L
A
L
M
Y
E
S
E
K
V
G
V
A
S
S
E
E
L
A
R
Q
R
G
V
L
E
R
T
E
K
M
V
D
K
M
D
Q
---------
D
L
K
I
S
Q
K
H
I
N
S
I
K
S
V
F
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
55
Fugue
41.50
11%
129
- C6 -
3HTK
-
A:
[1-60]
------------------------------------------------------
K
--
P
F
A
N
T
K
K
T
L
E
N
Q
V
E
E
L
T
E
K
C
S
L
K
T
D
E
F
L
K
A
K
E
K
I
N
E
I
F
E
K
L
---------
N
T
I
R
D
E
V
I
K
K
K
N
Q
N
E
Y
Y
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
41.29
21%
-8
* C4 *
3PNR
2
?
B:
[68-176]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
W
V
L
L
---
G
I
H
K
-
D
E
P
I
I
N
--
P
ENFPTKLTK
K
S
F
F
S
E
E
I
S
V
T
Q
-----------------
P
K
K
Y
--------------------------------------------------
M
-
Q
L
L
G
G
------
P
D
R
M
R
S
V
I
K
G
-
H
K
P
G
K
Y
Y
I
V
--
Y
S
-
Y
Y
R
P
F
S
P
T
S
G
----------------------------------------------------------------------------------------------
2
PsiBlast_PDB
36.12
32%
-20
- C5 -
1S58
-
?
A:
[58-121]
--------------------------------------------------------------------------------------------------------------------
S
P
A
A
S
S
C
H
N
A
S
---
G
K
E
A
K
---
V
C
T
-
I
T
P
I
M
G
Y
S
T
P
W
R
Y
L
--------
D
F
N
A
L
N
L
F
F
---
S
P
L
E
-
F
Q
H
L
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
35.97
33%
20
- C5 -
3M6Q
4
A:
[7-62]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
D
P
I
L
R
A
K
N
K
R
I
------
D
I
F
D
------
E
N
L
K
N
L
V
D
A
M
-
F
D
V
M
-
Y
K
T
--
D
Q
---
I
-
G
L
S
A
P
------
Q
V
G
L
N
V
Q
L
M
V
-
F
N
P
A
G
-----------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
35.58
33%
13
- C5 -
3PN5
4
A:
[7-62]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
D
P
I
L
R
A
K
N
K
R
I
------
D
I
F
D
------
E
N
L
K
N
L
V
D
A
M
-
F
D
V
M
-
Y
K
T
--
D
Q
---
I
-
G
L
S
A
P
------
Q
V
G
L
N
V
Q
L
M
V
-
F
N
P
A
G
-----------------------------------------------------------------------------------------------------------------
53
Fugue
35.48
15%
150
- C6 -
2JVG
-
SBI_STAAM
A:
[195-266]
-------------------------
G
A
M
V
S
I
E
K
A
I
V
R
H
D
E
R
V
K
S
A
N
D
A
I
S
K
L
N
E
K
--
D
S
I
E
N
R
R
L
A
Q
R
E
V
N
K
A
P
M
D
V
K
E
H
L
Q
K
Q
L
D
A
L
V
A
Q
K
D
A
E
K
K
V
---------
A
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
50
Fugue
34.15
16%
164
- C6 -
2X43
-
?
S:
[1-67]
----------------------------------------
M
D
Q
E
T
R
D
Q
M
K
N
A
A
A
E
--
A
K
D
N
V
H
D
K
I
Q
E
L
K
D
D
V
G
N
K
A
A
E
V
R
D
A
V
S
S
T
V
E
S
I
K
D
K
L
S
G
G
---------
S
S
S
R
A
S
S
Y
T
L
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
22.97
7%
332
* C5 *
2AP3
-
?
A:
[3-21]
----------------------
M
G
I
Q
R
P
T
S
T
T
T
D
K
K
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------