@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo1988: (2016-03-30 )
VTYKITSLAGDGIGPEIMTSGLQVLEAVAKKYNHTFEIESHPFGGAGIDVAQDPIPSSTLKACQDADAILLGAIGGPKWDNAPKRPEDGLLALRKALGLFANIRPIQVPSSITHLSPLKKEIVENTDFVVVRELTGGLYFGEPKHWDESAAVDSLTYTRAEIERIIEKAFEIAATRNKKVTSVDKANVLASSKLWRKIAEEVASRHPDITLEHLYIDAAAMLMIQRPTTFDVIVTENLFGDILSDEASVITGSLGMLPSASHAENGPSLYEPIHGSAPDIANQNIANPMSMISSVSMMLRQSFSLFKEADAIDAAATRTMQAGFLTADLGGNTTTTDFTNEVLKQIEGGE
Atome Classification :
(49 SA)
----------------.........10........20........30........40........50.-...-.----....60...-.....70........80.--.--.--.---.--.--..-90........100....-...110.......120.-.-...-...130...-------....140..---------..--.-----..150--.....---------....160.----......170.-...-------------.-.-------------.-180......--.-190........200.---...--..---.210.......220.......230.......240.......250.......260.........270.......280.......290.......300-.........-310.......320.-.-.....----330-----.----.----.----.....340.......350---------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----------------V
T
Y
K
I
T
SLAGDGI
G
P
E
I
M
T
S
G
L
Q
V
L
E
A
V
A
K
KYN
H
T
F
E
IESHPFGGAGIDV-A-QDP-I----
P
S
S
T
L
K
A
CQ-DA
D
A
I
L
L
GAIGGPKWDNA--P--K--R---P--E--
D
G
-
L
L
A
L
R
K
A
L
G
L
FANIRPI-QVPSSIT
H
L
S
P
L
K
K
E
-
I
-V-ENT-
D
F
V
V
V
R
E
LT-------GGLYFGEPK---------HW--D-----ESA----AV
D
S
L---------TY
T
R
A
E
I
E
----
R
I
I
E
K
A
F
E
I
A
-ATR-------------N-K-------------K-VTSV
D
K
A
N
V
--
L
-
A
-
S
S
K
L
W
R
K
I
A
E
E
V
A
---SRH--P
D
---
I
T
L
E
H
L
Y
I
D
A
A
A
M
L
MIQRPT
T
F
D
V
I
V
T
E
N
L
F
G
D
I
LSDEA
S
V
I
TGSLGMLPSA--SHAENGPSLYEPIHGSAPDIANQNIA
N
P
M
S
M
I
S
S
V
S
M
M
L
R
---
Q
S
F
S
L
F
K
EA-DA
I
D
A
A
A
T
R
T
M
Q
A
G
-
F
-
L
T
A
DL----GG------N----T----T----T
T
D
F
T
N
E
V
L
K
Q
IEGGE-----------------------------------------------------------------------------------------------------------------------------------------
109
HHSearch
96.90
59%
-99
- C6 -
3U1H
-
?
A:
[3-357]
------------------
K
K
I
A
V
L
P
G
D
G
I
G
P
E
V
M
E
A
A
I
E
V
L
K
A
V
A
E
R
F
G
H
E
F
E
F
E
Y
G
L
I
G
G
A
A
I
D
E
-
A
-
G
T
P
-
L
----
P
E
E
T
L
D
V
C
R
-
G
S
D
A
I
L
L
G
A
V
G
G
P
K
W
D
Q
N
P-
S
--
E
--
L
---
R
--
P
--
E
K
G
L
L
G
I
R
K
G
L
D
L
F
A
N
L
R
P
V
-
K
V
Y
D
S
L
A
D
A
S
P
L
K
K
E
-
V
-
I
-
E
G
V
-
D
L
V
I
V
R
E
L
T
-------
G
G
L
Y
F
---------------EE
G
-----
E
E
A
----
A
V
D
T
L
---------
L
Y
T
R
E
E
I
E
----
R
I
I
R
K
A
F
E
L
A
-
L
T
R
-------------
K
-
K
-------------
K
-
V
T
S
V
D
K
A
N
V
--
L
-
E
-
S
S
R
L
W
R
E
V
A
E
E
V
A
---
K
E
Y
--
P
D
---
V
E
L
E
H
M
L
V
D
N
A
A
M
Q
L
I
R
N
P
R
Q
F
D
V
I
V
T
E
N
M
F
G
D
I
L
S
D
E
A
S
M
I
T
G
S
L
G
M
L
P
S
A
--
S
L
S
T
D
G
L
G
L
Y
E
P
V
H
G
S
A
P
D
I
A
G
K
G
I
A
N
P
L
A
T
I
L
S
A
A
M
M
L
R
---
Y
S
F
G
L
E
E
E
A
-
K
A
I
E
K
A
V
E
K
V
L
A
E
G
-
Y
-
R
T
A
D
I
----
A
K
PG
G
K
--
Y
----
V
----
S
----
T
T
E
M
T
D
E
V
K
A
A
V
V
D
-------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
96.68
60%
-98
- C6 -
3U1H
-
?
A:
[4-351]
-------------------
K
I
A
V
L
P
G
D
G
I
G
P
E
V
M
E
A
A
I
E
V
L
K
A
V
A
E
R
F
G
H
E
F
E
F
E
Y
G
L
I
G
G
A
A
I
D
E
-
A
-
G
T
P
-
L
----
P
E
E
T
L
D
V
C
R
-
G
S
D
A
I
L
L
G
A
V
G
G
P
K
W
D
Q
N
--
P
--
S
EL
R
---
P
--
E
--
K
G
-
L
L
G
I
R
K
G
L
D
L
F
A
N
L
R
P
V
-
K
V
Y
D
S
L
A
D
A
S
P
L
K
K
E
-
V
-
I
-
E
G
V
-
D
L
V
I
V
R
E
L
T
-------
G
G
L
Y
F
---------------EE
G
-----
E
E
A
----
A
V
D
T
L
---------
L
Y
T
R
E
E
I
E
----
R
I
I
R
K
A
F
E
L
A
-
L
T
R
-------------
K
-
K
-------------
K
-
V
T
S
V
D
K
A
N
V
--
L
-
E
-
S
S
R
L
W
R
E
V
A
E
E
V
A
---
K
E
Y
--
P
D
---
V
E
L
E
H
M
L
V
D
N
A
A
M
Q
L
I
R
N
P
R
Q
F
D
V
I
V
T
E
N
M
F
G
D
I
L
S
D
E
A
S
M
I
T
G
S
L
G
M
L
P
S
A
--
S
L
S
T
D
G
L
G
L
Y
E
P
V
H
G
S
A
P
D
I
A
G
K
G
I
A
N
P
L
A
T
I
L
S
A
A
M
M
L
R
---
Y
S
F
G
L
E
E
E
A
-
K
A
I
E
K
A
V
E
K
V
L
A
E
G
-
Y
-
R
T
A
D
I
AKPG
G
K
------
Y
----
V
----
S
----
T
T
E
M
T
D
E
V
-------------------------------------------------------------------------------------------------------------------------------------------------
107
HHSearch
93.94
52%
-89
- C6 -
1VLC
1
LEU3_THEMA
A:
[12-364]
-----------------
H
M
K
I
A
V
L
P
G
D
G
I
G
P
E
V
V
R
E
A
L
K
V
L
E
V
V
E
K
K
T
G
K
T
F
E
K
V
F
G
H
I
G
G
D
A
I
D
R
-
F
-
G
E
P
-
L
----
P
E
E
T
K
K
I
C
L
-
E
A
D
A
I
F
L
G
S
V
G
G
P
K
W
D
D
L
PP
E
--
K
--
R
---
P
--
E
--
I
G
G
L
L
A
L
R
K
M
L
N
L
Y
A
N
I
R
P
I
-
K
V
Y
R
S
L
V
H
V
S
P
L
K
E
K
V
I
-
G
-
S
G
V
-
D
L
V
T
V
R
E
L
S
-------
Y
G
V
Y
Y
G
Q
P
R
---------
G
L
--
D
-----
E
E
K
----
G
F
D
T
M
---------
I
Y
D
R
K
T
V
E
----
R
I
A
R
T
A
F
E
I
A
-
K
N
R
-------------
R
-
K
-------------
K
-
V
T
S
V
D
K
A
N
V
--
L
-
Y
-
S
S
M
L
W
R
K
V
V
N
E
V
A
---
R
E
Y
--
P
D
---
V
E
L
T
H
I
Y
V
D
N
A
A
M
Q
L
I
L
K
P
S
Q
F
D
V
I
L
T
T
N
M
F
G
D
I
L
S
D
E
S
A
A
L
P
G
S
L
G
L
L
P
S
A
--
S
F
G
D
--
K
N
L
Y
E
P
A
G
G
S
A
P
D
I
A
G
K
N
I
A
N
P
I
A
Q
I
L
S
L
A
M
M
L
E
---
H
S
F
G
M
V
E
E
A
-
R
K
I
E
R
A
V
E
L
V
I
E
E
G
-
Y
-
R
T
R
D
I
----
A
E
------
D
PEKA
V
----
S
----
T
S
Q
M
G
D
L
I
C
K
K
L
E
E
-------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
93.91
51%
-88
- C6 -
1VLC
1
LEU3_THEMA
A:
[14-363]
-------------------
K
I
A
V
L
P
G
D
G
I
G
P
E
V
V
R
E
A
L
K
V
L
E
V
V
E
K
K
T
G
K
T
F
E
K
V
F
G
H
I
G
G
D
A
I
D
R
-
F
-
G
E
P
-
L
----
P
E
E
T
K
K
I
C
L
-
E
A
D
A
I
F
L
G
S
V
G
G
P
K
W
D
D
L
--
P
PE
K
--
R
---
P
--
E
I-
G
G
-
L
L
A
L
R
K
M
L
N
L
Y
A
N
I
R
P
I
-
K
V
Y
R
S
L
V
H
V
S
P
L
K
E
K
-
V
-
I
G
S
G
V
-
D
L
V
T
V
R
E
L
S
-------
Y
G
V
Y
Y
G
Q
P
R
---------
G
L
--
D
-----
E
E
K
----
G
F
D
T
M
---------
I
Y
D
R
K
T
V
E
----
R
I
A
R
T
A
F
E
I
A
-
K
N
R
-------------
R
-
K
-------------
K
-
V
T
S
V
D
K
A
N
V
--
L
-
Y
-
S
S
M
L
W
R
K
V
V
N
E
V
A
---
R
E
Y
--
P
D
---
V
E
L
T
H
I
Y
V
D
N
A
A
M
Q
L
I
L
K
P
S
Q
F
D
V
I
L
T
T
N
M
F
G
D
I
L
S
D
E
S
A
A
L
P
G
S
L
G
L
L
P
S
A
--
S
F
G
D
K
--
N
L
Y
E
P
A
G
G
S
A
P
D
I
A
G
K
N
I
A
N
P
I
A
Q
I
L
S
L
A
M
M
L
E
---
H
S
F
G
M
V
E
E
A
-
R
K
I
E
R
A
V
E
L
V
I
E
E
G
-
Y
-
R
T
R
D
I
----
A
E
------
D
PEKA
V
----
S
----
T
S
Q
M
G
D
L
I
C
K
K
L
E
--------------------------------------------------------------------------------------------------------------------------------------------
103
HHSearch
93.47
48%
-88
- C6 -
1A05
4
LEU3_ACIFR
A:
[1-357]
-----------------
M
K
K
I
A
I
F
A
G
D
G
I
G
P
E
I
V
A
A
A
R
Q
V
L
D
A
V
D
Q
A
A
H
L
G
L
R
C
T
E
G
L
V
G
G
A
A
L
D
A
-
S
-
D
D
P
-
L
----
P
A
A
S
L
Q
L
A
M
-
A
A
D
A
V
I
L
G
A
V
G
G
P
R
W
D
A
Y
PP
A
--
K
--
R
---
P
--
E
--
Q
G
-
L
L
R
L
R
K
G
L
D
L
Y
A
N
L
R
P
A
-
Q
I
F
P
Q
L
L
D
A
S
P
L
R
P
E
-
L
-
V
-
R
D
V
-
D
I
L
V
V
R
E
L
T
-------
G
D
I
Y
F
G
Q
P
R
---------
G
L
--
E
V
I
DG-
K
R
R
----
G
F
N
T
M
---------
V
Y
D
E
D
E
I
R
----
R
I
A
H
V
A
F
R
A
A
-
Q
G
R
-------------
R
-
K
-------------
Q
-
L
C
S
V
D
K
A
N
V
--
L
-
E
-
T
T
R
L
W
R
E
V
V
T
E
V
A
---
R
D
Y
--
P
D
---
V
R
L
S
H
M
Y
V
D
N
A
A
M
Q
L
I
R
A
P
A
Q
F
D
V
L
L
T
G
N
M
F
G
D
I
L
S
D
E
A
S
Q
L
T
G
S
I
G
M
L
P
S
A
--
S
L
G
E
-
G
R
A
M
Y
E
P
I
H
G
S
A
P
D
I
A
G
Q
D
K
A
N
P
L
A
T
I
L
S
V
A
M
M
L
R
---
H
S
L
N
A
E
P
W
A
-
Q
R
V
E
A
A
V
Q
R
V
L
D
Q
G
-
L
-
R
T
A
D
I
----
A
A
------
P
----
G
T
P
V
I
G
----
T
K
A
M
G
A
A
V
V
N
A
L
N
L
K
------------------------------------------------------------------------------------------------------------------------------------------
55
PsiBlast_CBE
92.92
47%
-87
- C6 -
3R8W
5
LEU32_ARATH
A:
[43-398]
------------------
Y
T
I
T
L
L
P
G
D
G
I
G
P
E
V
V
S
I
A
K
N
V
L
Q
Q
A
G
S
L
E
G
V
E
F
N
F
R
E
M
P
I
G
G
A
A
L
D
L
-
V
-
G
V
P
-
L
----
P
E
E
T
I
S
A
A
K
-
E
S
D
A
V
L
L
G
A
I
G
G
Y
K
W
D
N
N
--
E
--
K
HL
R
---
P
--
E
--
K
G
-
L
L
Q
I
R
A
A
L
K
V
F
A
N
L
R
P
A
-
T
V
L
P
Q
L
V
D
A
S
T
L
K
R
E
-
V
-
A
-
E
G
V
-
D
L
M
V
V
R
E
L
T
-------
G
G
I
Y
F
G
E
P
R
---------
G
I
--
K
T
NENG
E
E
V
----
G
F
N
T
E
---------
V
Y
A
A
H
E
I
D
----
R
I
A
R
V
A
F
E
T
A
-
R
K
R
-------------
R
-
G
-------------
K
-
L
C
S
V
D
K
A
N
V
--
L
-
E
-
A
S
I
L
W
R
K
R
V
T
A
L
A
---
S
E
Y
--
P
D
---
V
E
L
S
H
M
Y
V
D
N
A
A
M
Q
L
V
R
D
P
K
Q
F
D
T
I
V
T
N
N
I
F
G
D
I
L
S
D
E
A
S
M
I
T
G
S
I
G
M
L
P
S
A
--
S
L
S
D
S
G
P
G
L
F
E
P
I
H
G
S
A
P
D
I
A
G
Q
D
K
A
N
P
L
A
T
I
L
S
A
A
M
L
L
K
---
Y
G
L
G
E
E
K
A
A
-
K
R
I
E
D
A
V
L
V
A
L
N
N
G
-
F
-
R
T
G
D
I
----
Y
S
------
A
----
G
----
T
K
L
V
G
C
K
E
M
G
E
E
V
L
K
S
V
D
--------------------------------------------------------------------------------------------------------------------------------------------
54
PsiBlast_CBE
92.75
47%
-88
- C6 -
3R8W
7
LEU32_ARATH
B:
[43-398]
------------------
Y
T
I
T
L
L
P
G
D
G
I
G
P
E
V
V
S
I
A
K
N
V
L
Q
Q
A
G
S
L
E
G
V
E
F
N
F
R
E
M
P
I
G
G
A
A
L
D
L
-
V
-
G
V
P
-
L
----
P
E
E
T
I
S
A
A
K
-
E
S
D
A
V
L
L
G
A
I
G
G
Y
K
W
D
N
N
--
E
--
K
HL
R
---
P
--
E
--
K
G
-
L
L
Q
I
R
A
A
L
K
V
F
A
N
L
R
P
A
-
T
V
L
P
Q
L
V
D
A
S
T
L
K
R
E
-
V
-
A
-
E
G
V
-
D
L
M
V
V
R
E
L
T
-------
G
G
I
Y
F
G
E
P
R
---------
G
I
--
K
T
NE
N
G
E
E
V
----
G
F
N
T
E
---------
V
Y
A
A
H
E
I
D
----
R
I
A
R
V
A
F
E
T
A
-
R
K
R
-------------
R
-
G
-------------
K
-
L
C
S
V
D
K
A
N
V
--
L
-
E
-
A
S
I
L
W
R
K
R
V
T
A
L
A
---
S
E
Y
--
P
D
---
V
E
L
S
H
M
Y
V
D
N
A
A
M
Q
L
V
R
D
P
K
Q
F
D
T
I
V
T
N
N
I
F
G
D
I
L
S
D
E
A
S
M
I
T
G
S
I
G
M
L
P
S
A
--
S
L
S
D
S
G
P
G
L
F
E
P
I
H
G
S
A
P
D
I
A
G
Q
D
K
A
N
P
L
A
T
I
L
S
A
A
M
L
L
K
---
Y
G
L
G
E
E
K
A
A
-
K
R
I
E
D
A
V
L
V
A
L
N
N
G
-
F
-
R
T
G
D
I
----
Y
S
------
A
----
G
----
T
K
L
V
G
C
K
E
M
G
E
E
V
L
K
S
V
D
--------------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
92.53
54%
-84
- C6 -
1V5B
3
LEU3_BACCO
H:
[4-355]
-------------------
K
L
A
V
L
P
G
D
G
I
G
P
E
V
M
D
A
A
I
R
V
L
K
T
V
L
D
N
D
G
H
E
A
V
F
E
N
A
L
I
G
G
A
A
I
D
E
-
A
-
G
T
P
-
L
----
P
E
E
T
L
D
I
C
R
-
R
S
D
A
I
L
L
G
A
V
G
G
P
K
W
D
H
N
--
P
--
A
SL
R
---
P
--
E
--
K
G
-
L
L
G
L
R
K
E
M
G
L
F
A
N
L
R
P
V
-
K
A
Y
A
T
L
L
N
A
S
P
L
K
R
E
-
R
-
V
-
E
N
V
-
D
L
V
I
V
R
E
L
T
-------
G
G
L
Y
F
G
R
P
S
---------
E
R
--
R
GPG--
E
N
E
----
V
V
D
T
L
---------
A
Y
T
R
E
E
I
E
----
R
I
I
E
K
A
F
Q
L
A
-
Q
I
R
-------------
R
-
K
-------------
K
-
L
A
S
V
D
K
A
N
V
--
L
-
E
-
S
S
R
M
W
R
E
I
A
E
E
T
A
---
K
K
Y
--
P
D
---
V
E
L
S
H
M
L
V
D
S
T
A
M
Q
L
I
A
N
P
G
Q
F
D
V
I
V
T
E
N
M
F
G
D
I
L
S
D
L
A
S
V
I
T
G
S
L
G
M
L
P
S
A
--
S
L
R
S
D
R
F
G
M
Y
E
P
V
H
G
S
A
P
D
I
A
G
Q
G
K
A
N
P
L
G
T
V
L
S
A
A
L
M
L
R
---
Y
S
F
G
L
E
K
E
A
-
A
A
I
E
K
A
V
D
D
V
L
Q
D
G
-
Y
-
C
T
G
D
L
QVAN
G
K
------
V
----
V
----
S
----
T
I
E
L
T
D
R
L
I
E
K
L
---------------------------------------------------------------------------------------------------------------------------------------------
123
Fugue
92.31
54%
-90
- C6 -
2AYQ
-
LEU3_BACCO
A:
[1-356]
----------------
M
K
M
K
L
A
V
L
P
G
D
G
I
G
P
E
V
M
D
A
A
I
R
V
L
K
T
V
L
D
N
D
G
H
E
A
V
F
E
N
A
L
I
G
G
A
A
I
D
E
-
A
G-
T
P
-
L
----
P
E
E
T
L
D
I
C
R
-
R
S
D
A
I
L
L
G
A
V
G
G
P
K
W
D
H
N
--
P
--
A
--
S
LR
P
E
-----
K
G
-
L
L
G
L
R
K
E
M
G
L
F
A
N
L
R
P
V
-
K
A
Y
A
T
L
L
N
A
S
P
L
K
R
E
-
R
-
V
-
E
N
V
-
D
L
V
I
V
R
E
L
T
-------
G
G
L
Y
F
G
R
P
S
---------
E
R
--
R
------
G
P
---------GEN
E
V
V
D
T
L
A
Y
T
R
E
E
I
E
----
R
I
I
E
K
A
F
Q
L
A
-
Q
I
R
-------------
R
-
K
-------------
K
-
L
A
S
V
D
K
A
N
V
--
L
-
E
-
S
S
R
M
W
R
E
I
A
E
E
T
A
---
K
-
K
Y
P-
D
---
V
E
L
S
H
M
L
V
D
S
T
S
M
Q
L
I
A
N
P
G
Q
F
D
V
I
V
T
E
N
M
F
G
D
I
L
S
D
E
A
S
V
I
T
G
S
L
G
M
L
P
S
A
--
S
L
R
S
D
R
F
G
M
Y
E
P
V
H
G
S
A
P
D
I
A
G
Q
G
K
A
N
P
L
G
T
V
L
S
A
A
L
M
L
R
---
Y
S
F
G
L
E
K
E
A
-
A
A
I
E
K
A
V
D
D
V
L
Q
D
G
-
Y
-
C
T
G
D
L
QVAN
G
K
------
V
----
V
----
S
----
T
I
E
L
T
D
R
L
I
E
K
L
N
--------------------------------------------------------------------------------------------------------------------------------------------
27
PsiBlast_CBE
92.29
48%
-82
- C6 -
4F7I
16
LEU3_THET8
C:
[3-345]
-----------------
S
M
K
V
A
V
L
P
G
D
G
I
G
P
E
V
T
E
A
A
L
K
V
L
R
A
L
D
E
A
E
G
L
G
L
A
Y
E
V
F
P
F
G
G
A
A
I
D
A
-
F
-
G
E
P
-
F
----
P
E
P
T
R
K
G
V
E
-
E
A
E
A
V
L
L
G
S
V
G
G
P
K
W
D
G
L
--
P
--
R
KI
R
---
P
--
E
--
T
G
-
L
L
S
L
R
K
S
Q
D
L
F
A
N
L
R
P
A
-
K
V
F
P
G
L
E
R
L
S
P
L
K
E
E
-
I
-
A
-
R
G
V
-
D
V
L
I
V
R
E
L
T
-------
G
G
I
Y
F
G
E
P
R
---------
G
M
--
S
-----
E
A
E
----
A
W
N
T
E
---------
R
Y
S
K
P
E
V
E
----
R
V
A
R
V
A
F
E
A
A
-
R
K
R
-------------
R
-
K
-------------
H
-
V
V
S
V
D
K
A
N
V
--
L
-
E
-
V
G
E
F
W
R
K
T
V
E
E
V
G
---
R
G
Y
--
P
D
---
V
A
L
E
H
Q
Y
V
D
A
M
A
M
H
L
V
R
S
P
A
R
F
D
V
V
V
T
G
N
I
F
G
D
I
L
S
D
L
A
S
V
L
P
G
S
L
G
L
L
P
S
A
--
S
L
G
R
G
T
P
-
V
F
E
P
V
H
G
S
A
P
D
I
A
G
K
G
I
A
N
P
T
A
A
I
L
S
A
A
M
M
L
E
---
H
A
F
G
L
V
E
L
A
-
R
K
V
E
D
A
V
A
K
A
L
L
E
--
T
-
P
P
P
D
L
----
G
G
------
S
----
A
----
G
----
T
E
A
F
T
A
T
V
L
R
-----------------------------------------------------------------------------------------------------------------------------------------------
39
PsiBlast_CBE
92.15
48%
-83
- C6 -
4WUO
16
LEU3_THET8
A:
[3-345]
-----------------
S
M
K
V
A
V
L
P
G
D
G
I
G
P
E
V
T
E
A
A
L
K
V
L
R
A
L
D
E
A
E
G
L
G
L
A
Y
E
V
F
P
F
G
G
A
A
I
D
A
-
F
-
G
E
P
-
F
----
P
E
P
T
R
K
G
V
E
-
E
A
E
A
V
L
L
G
S
V
G
G
P
K
W
D
G
L
--
P
--
R
KI
R
---
P
--
E
--
T
G
-
L
L
S
L
R
K
S
Q
D
L
F
A
N
L
R
P
A
-
K
V
F
P
G
L
E
R
L
S
P
L
K
E
E
-
I
-
A
-
R
G
V
-
D
V
L
I
V
R
E
L
T
-------
G
G
I
Y
F
G
E
P
R
---------
G
M
--
S
-----
E
A
E
----
A
W
N
T
E
---------
R
Y
S
K
P
E
V
E
----
R
V
A
R
V
A
F
E
A
A
-
R
K
R
-------------
R
-
K
-------------
H
-
V
V
S
V
D
K
A
N
V
--
L
-
E
-
V
G
E
F
W
R
K
T
V
E
E
V
G
---
R
G
Y
--
P
D
---
V
A
L
E
H
Q
Y
V
D
A
M
A
M
H
L
V
R
S
P
A
R
F
D
V
V
V
T
G
N
I
F
G
D
I
L
S
D
L
A
S
V
L
P
G
S
L
G
L
L
P
S
A
--
S
L
G
R
G
T
P
-
V
F
A
P
V
H
G
S
A
P
D
I
A
G
K
G
I
A
N
P
T
A
A
I
L
S
A
A
M
M
L
E
---
H
A
F
G
L
V
E
L
A
-
R
K
V
E
D
A
V
A
K
A
L
L
E
--
T
-
P
P
P
D
L
----
G
G
------
S
----
A
----
G
----
T
E
A
F
T
A
T
V
L
R
-----------------------------------------------------------------------------------------------------------------------------------------------
50
PsiBlast_CBE
92.08
47%
-82
- C6 -
1CNZ
8
LEU3_SALTY
B:
[4-357]
-----------------
N
Y
H
I
A
V
L
P
G
D
G
I
G
P
E
V
M
A
Q
A
L
K
V
M
D
A
V
R
S
R
F
D
M
R
I
T
T
S
H
Y
D
V
G
G
I
A
I
D
N
-
H
-
G
H
P
-
L
----
P
K
A
T
V
E
G
C
E
-
Q
A
D
A
I
L
F
G
S
V
G
G
P
K
W
E
N
L
--
P
PE
S
--
Q
---
P
--
E
--
R
G
A
L
L
P
L
R
K
H
F
K
L
F
S
N
L
R
P
A
-
K
L
Y
Q
G
L
E
A
F
C
P
L
R
A
D
-
I
-
A
-
A
N
G
F
D
I
L
C
V
R
E
L
T
-------
G
G
I
Y
F
G
Q
P
K
---------
G
R
--
E
-----
G
S
G
QYEK
A
F
D
T
E
---------
V
Y
H
R
F
E
I
E
----
R
I
A
R
I
A
F
E
S
A
-
R
K
R
-------------
R
-
R
-------------
K
-
V
T
S
I
D
K
A
N
V
--
L
-
Q
-
S
S
I
L
W
R
E
I
V
N
D
V
A
---
K
T
Y
--
P
D
---
V
E
L
A
H
M
Y
I
D
N
A
T
M
Q
L
I
K
D
P
S
Q
F
D
V
L
L
C
S
N
L
F
G
D
I
L
S
D
E
C
A
M
I
T
G
S
M
G
M
L
P
S
A
--
S
L
N
E
Q
G
F
G
L
Y
E
P
A
G
G
S
A
P
D
I
A
G
K
N
I
A
N
P
I
A
Q
I
L
S
L
A
L
L
L
R
---
Y
S
L
D
A
N
D
A
A
-
T
A
I
E
Q
A
I
N
R
A
L
E
E
G
-
V
-
R
T
G
D
L
AR--
G
A
------
A
----
A
----
V
----
S
T
D
E
M
G
D
I
I
A
R
----------------------------------------------------------------------------------------------------------------------------------------------
28
PsiBlast_CBE
92.07
48%
-82
- C6 -
4F7I
12
LEU3_THET8
B:
[3-345]
-----------------
S
M
K
V
A
V
L
P
G
D
G
I
G
P
E
V
T
E
A
A
L
K
V
L
R
A
L
D
E
A
E
G
L
G
L
A
Y
E
V
F
P
F
G
G
A
A
I
D
A
-
F
-
G
E
P
-
F
----
P
E
P
T
R
K
G
V
E
-
E
A
E
A
V
L
L
G
S
V
G
G
P
K
W
D
G
L
--
P
--
R
KI
R
---
P
--
E
--
T
G
-
L
L
S
L
R
K
S
Q
D
L
F
A
N
L
R
P
A
-
K
V
F
P
G
L
E
R
L
S
P
L
K
E
E
-
I
-
A
-
R
G
V
-
D
V
L
I
V
R
E
L
T
-------
G
G
I
Y
F
G
E
P
R
---------
G
M
--
S
-----
E
A
E
----
A
W
N
T
E
---------
R
Y
S
K
P
E
V
E
----
R
V
A
R
V
A
F
E
A
A
-
R
K
R
-------------
R
-
K
-------------
H
-
V
V
S
V
D
K
A
N
V
--
L
-
E
-
V
G
E
F
W
R
K
T
V
E
E
V
G
---
R
G
Y
--
P
D
---
V
A
L
E
H
Q
Y
V
D
A
M
A
M
H
L
V
R
S
P
A
R
F
D
V
V
V
T
G
N
I
F
G
D
I
L
S
D
L
A
S
V
L
P
G
S
L
G
L
L
P
S
A
--
S
L
G
R
G
T
P
-
V
F
E
P
V
H
G
S
A
P
D
I
A
G
K
G
I
A
N
P
T
A
A
I
L
S
A
A
M
M
L
E
---
H
A
F
G
L
V
E
L
A
-
R
K
V
E
D
A
V
A
K
A
L
L
E
--
T
-
P
P
P
D
L
----
G
G
------
S
----
A
----
G
----
T
E
A
F
T
A
T
V
L
R
-----------------------------------------------------------------------------------------------------------------------------------------------
29
PsiBlast_CBE
92.05
48%
-82
- C6 -
4F7I
19
LEU3_THET8
A:
[3-345]
-----------------
S
M
K
V
A
V
L
P
G
D
G
I
G
P
E
V
T
E
A
A
L
K
V
L
R
A
L
D
E
A
E
G
L
G
L
A
Y
E
V
F
P
F
G
G
A
A
I
D
A
-
F
-
G
E
P
-
F
----
P
E
P
T
R
K
G
V
E
-
E
A
E
A
V
L
L
G
S
V
G
G
P
K
W
D
G
L
--
P
--
R
KI
R
---
P
--
E
--
T
G
-
L
L
S
L
R
K
S
Q
D
L
F
A
N
L
R
P
A
-
K
V
F
P
G
L
E
R
L
S
P
L
K
E
E
-
I
-
A
-
R
G
V
-
D
V
L
I
V
R
E
L
T
-------
G
G
I
Y
F
G
E
P
R
---------
G
M
--
S
-----
E
A
E
----
A
W
N
T
E
---------
R
Y
S
K
P
E
V
E
----
R
V
A
R
V
A
F
E
A
A
-
R
K
R
-------------
R
-
K
-------------
H
-
V
V
S
V
D
K
A
N
V
--
L
-
E
-
V
G
E
F
W
R
K
T
V
E
E
V
G
---
R
G
Y
--
P
D
---
V
A
L
E
H
Q
Y
V
D
A
M
A
M
H
L
V
R
S
P
A
R
F
D
V
V
V
T
G
N
I
F
G
D
I
L
S
D
L
A
S
V
L
P
G
S
L
G
L
L
P
S
A
--
S
L
G
R
G
T
P
-
V
F
E
P
V
H
G
S
A
P
D
I
A
G
K
G
I
A
N
P
T
A
A
I
L
S
A
A
M
M
L
E
---
H
A
F
G
L
V
E
L
A
-
R
K
V
E
D
A
V
A
K
A
L
L
E
--
T
-
P
P
P
D
L
----
G
G
------
S
----
A
----
G
----
T
E
A
F
T
A
T
V
L
R
-----------------------------------------------------------------------------------------------------------------------------------------------