@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs0146: (2015-11-28 )
MADKNRTFKLVGAGSSSTQEKIEKPALSFMQDAWRRLKKNKLAVVSLYLLALLLTFSLASNLFVTQKDANGFDSKKVTTYRNLPPKLSSNLPFWNGSIKYAGNTESTDAYKSQNVPEKVKYALGTDSLGRSVAKRIIVGIRISLLVAIAATFIDLIIGVTYGLVSGFAGGRLDTLMQRIVEVISSIPNLVIVTMLGLVLGNGITAIIISIAFTGWTSMSRQVRNLTLSYREREFVLAARSLGESPIKIAFKHILPNISGIIIVQIMMTIPSAIMYEAVLSAINLGVKPPTASLGSLISDAQENLQYYPYQVILPALALVMISLAFILLGDGLRDAFDPKSSDE
Atome Classification :
(20 SA)
-------------------------------------------------------------------.......-----------..10........20........30........40-.........50...---.....---60........70........80..-------......90......-----..100-........110...--....120--........------------130..-----.....140....---------...150...-----....160..--..-------..-----------..--------.-------170.......180...---....190---....----..------..200----.----------------.-------------------------.......210.......220-------.......230-------------.........240---.....--...250.......260.......-----.270.......-280......---------.290.......300.---.--.-....310.......320.....-------------..330.......340.---------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-------------------------------------------------------------------MADKN
R
T
-----------
F
K
L
V
GAGSS
S
T
Q
E
K
I
E
K
P
A
L
S
F
M
Q
D
A
W
R
R
L
K
KN--
K
L
A
V
V
S
L
Y
L
L
A
L
L
L
---
T
F
S
L
A---S
N
L
F
V
TQKDANGFDSK
K
V
T
TYRNL-------PPKLSSNLPFWNG
S
-----
I
K
YA--GNTESTDAYKSQN
V
--
P
E
K
V
K
Y
---ALG
T
D
S
L
G
------------
R
S
V
A
K
-----
R
I
I
V
G
I
R
I
S
L
L
V
---------
A
I
A
A
T
F
I
D
L
-----
I
I
G
V
T
--
Y
G
--
L
V
-------SG-----------FA--------G-------G
R
L
D
T
L
M
Q
R
I
V
E
V
I
S
S---I
P
N
L
V
I
----
V
T
M
L
----
G
L
------
V
LG------N----------------G-------------------------
I
T
A
I
I
I
S
I
A
FTG
W
T
S
M
S
R
Q
V
-------
R
N
L
T
LSYR---------------E
R
E
F
V
L
A
A
R
SL----GES
P
I
--
K
I
A
F
K
H
I
LPNI
S
G
I
I
-
I
V
Q
I
M
M
T-----I
P
S
A
I
M
Y
E
A
V
L
-
S
A
I
NLGVKP---------P
T
A
S
L
G
S
L
I
S
D
A
Q
E
N
---
L
--Q-YY
P
Y
Q
V
I
L
P
A
L
A
L
V
M
I
S
L
A
F
I
L
-------------LGD
G
L
R
DAFDPKSSDE---------------------------------------------
25
Fugue
87.43
19%
-87
- C3 -
4K70
22
?
A:
[2-483]
---------------------------------------------PG
S
M
E
A
L
V
R
A
L
E
EADHAV
A
T
V
V
Q
S
R
I
L
E
F
-----------
F
M
A
A
G
R
E
T
P
A
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W
A
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A
L
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L
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A
Y
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E
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C
--
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A
A
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L
A
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L
A
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RL
R
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W
D
EGT
A
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L
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L
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V
V
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G
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D
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T
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A
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RTSAEFG
P
D
A
M
F
R
L
V
S
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W
C
A
A
-----
F
D
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A
L
A
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A
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A
D
D
V
L
A
A
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R
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V
P
P
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Q
T
A
R
---
A
L
V
Q
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TLYDM
D
F
V
Q
D
G
L
R
Y
V
A
Q
-----
H
T
N
W
A
L
P
L
A
L
A
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R
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M
Q
NEGLK
P
L
T
R
A
L
F
A
L
-----
T
I
A
D
E
--
F
-------------------------
F
H
--------
D
-------
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L
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A
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A
A
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A
---
V
D
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----
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-
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----
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------
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N
A
------
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PR--------------
T
-------------------------
A
V
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S
A
A
L
A
H
G
D
A
Y
V
R
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L
-------
R
P
G
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V
A
R
R
L
R
TDQGVLALLDPGA
Q
A
V
H
V
A
A
A
A
D
L
----
D
H
T
Q
V
DA
T
G
V
W
E
A
V
Q
A
S
A
S
P
L
Q
-
V
V
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A
L
V
T
A
GFT
R
R
H
C
D
L
L
E
R
A
V
L
D
R
A
P
R
L
T
D
A
Q
---------
R
A
V
G
C
T
A
V
V
G
G
V
V
H
R
---
L
LD
D
-
Y
G
P
G
L
D
Y
V
R
A
Y
T
D
V
A
D
T
L
E
P
L
Y
GDVTAALGLPEK
G
V
E
H
V
V
R
H
C
M
A
P
R
P
P
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E
H
V
G
A
A
R
A
A
L
L
R
E
V
A
A
A
E
R
R
A
GLAHS
A
A
R
E
A
L
N
T
W
L
A
F
R
A
Q
S
R
WGL
9
HHSearch
77.23
20%
-136
- C6 -
3TUI
-
METI_ECOLI
A:
[2-216]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
------------
E
P
M
M
W
-----
L
L
V
R
G
V
W
E
T
L
A
M
---------
T
F
V
S
G
F
F
G
F
-----
V
I
G
L
P
--
V
G
--
V
L
-------
L
Y
-----------
V
T
--------
R
PGQIIAN
A
K
L
Y
R
T
V
S
A
I
V
N
I
F
R
S
---
I
P
F
I
I
L
----
L
V
W
M
----
I
P
------
F
T
R
V
I
VGTS
I
----------------
G
-------------------------
L
Q
A
A
I
V
P
L
T
V
G
A
A
P
F
I
A
R
M
V
-------
E
N
A
-
L
L
E
I
---------------
P
T
G
L
I
E
A
S
R
A
M
----
G
A
T
P
M
--
Q
I
V
R
K
V
L
L
P
E
A
L
P
G
L
-
V
N
A
A
T
I
T
-----
L
I
T
L
V
G
Y
S
A
M
G
-
G
A
V
G
---------------
A
G
G
L
G
Q
I
G
Y
Q
Y
G
Y
I
---
G
----
Y
N
A
T
V
M
N
T
V
L
V
L
L
V
I
L
V
Y
L
I
Q
F
-------------
A
G
D
R
I
V
R
A
V
T
R
--------------------------------------------------
10
HHSearch
76.44
21%
-152
- C6 -
3D31
-
?
C:
[79-283]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
V
I
S
S
I
F
L
S
L
Y
A
---------
G
F
L
A
T
L
L
A
L
-----
L
L
G
A
P
--
T
G
--
Y
I
-------
L
A
-----------
R
F
--------
D
-------
F
P
G
K
R
L
V
E
S
I
I
D
V
P
V
V
---
V
P
H
T
V
A
----
G
I
A
L
----
L
T
------
V
F
G
------
S
RGLIGEPLESYIQFRD
A
-------------------------
L
P
G
I
V
V
A
M
L
F
V
S
M
P
Y
L
A
N
S
A
-------
R
E
G
-
F
K
S
V
---------------
D
P
R
L
E
N
A
A
R
S
L
----
G
A
P
L
W
--
K
A
F
F
F
V
T
L
P
L
S
A
R
Y
L
-
L
I
G
S
V
M
T
-----
W
A
R
A
I
S
E
F
G
A
V
-
V
I
L
A
Y
Y
-------------
P
M
V
G
P
T
L
I
Y
D
R
F
I
S
---
Y
----
G
-
L
S
A
S
R
P
I
A
V
L
L
I
L
V
T
L
S
I
F
L
-------------
V
I
R
----------------------------------------------------------
11
HHSearch
69.96
18%
-143
- C6 -
2ONK
-
WTPB_ARCFU
C:
[68-275]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
-----
A
V
W
K
V
V
L
T
T
Y
Y
A
---------
A
L
I
S
T
L
I
A
V
-----
I
F
G
T
P
--
L
A
--
Y
I
-------
L
A
-----------
R
K
--------
S
-------
F
P
G
K
S
V
V
E
G
I
V
D
L
P
V
V
---
I
P
H
T
V
A
----
G
I
A
L
----
L
V
------
V
F
G
------
S
----------------
S
GLIGSFSPLKFVDA-----------
L
P
G
I
V
V
A
M
L
F
V
S
V
P
I
Y
I
N
Q
A
-------
K
E
G
-
F
A
S
V
---------------
D
V
R
L
E
H
V
A
R
T
L
----
G
S
S
P
L
--
R
V
F
F
T
V
S
L
P
L
S
V
R
H
I
-
V
A
G
A
I
M
S
-----
W
A
R
G
I
S
E
F
G
A
V
-
V
V
I
A
Y
Y
-------------
P
M
I
A
P
T
L
I
Y
E
R
Y
L
S
---
E
----
G
-
L
S
A
A
M
P
V
A
A
I
L
I
L
L
S
L
A
V
F
V
-------------
A
L
R
I
I
V
G
------------------------------------------------------
20
Fugue
68.39
18%
-82
* C6 *
2ONK
-
WTPB_ARCFU
C:
[24-275]
----------------------------------------------------------------------------------------------------------------
M
R
L
L
F
S
--
A
L
L
A
L
L
S
S
I
I
L
L
F
V
---
L
L
P
V
A
---
A
T
V
T
L
Q
L
F
N
F
D
E
F
L
K
A
A
S
D
--------------------
P
A
V
W
K
V
-----
V
L
T
T
--
Y
Y
A
A
L
I
S
T
L
I
A
V
I
F
--
G
T
P
L
A
Y
---
I
L
A
R
K
S
F
P
------------
G
K
S
V
V
-----
E
G
I
V
D
L
P
V
V
I
P
H
---------
T
V
A
G
I
A
L
L
V
-----
V
F
G
S
----------------
S
G
-----------
L
I
--------
G
-------------------------------------
S
F
S
----
P
L
------
K
F
V
------
D
----------------
A
-------------------------
L
P
G
I
V
V
A
M
L
F
V
S
V
P
I
Y
I
N
Q
A
-------
K
E
G
F
A
S
V
----------------
D
V
R
L
E
H
V
A
R
T
L
----
G
S
S
P
L
--
R
V
F
F
T
V
S
L
P
L
S
V
R
H
I
-
V
A
G
A
I
M
S
-----
W
A
R
G
I
S
E
F
G
A
V
-
V
V
I
--
A
Y
Y
P
---------
M
I
A
P
T
L
I
Y
E
R
Y
L
S
E
G
---
L
--
S
A
A
M
P
V
A
A
I
L
I
L
L
S
L
A
V
F
V
A
L
R
I
I
-------------
V
G
-----------------------------------------------------------
12
HHSearch
66.07
12%
-122
- C6 -
3RLF
2
MALF_ECOLI
F:
[250-503]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
L
--
S
P
G
Y
T
V
---
T
T
G
W
K
N
F
T
------------
R
V
F
T
D
EGIQK
P
F
L
A
I
F
V
W
T
V
V
F
---------
S
L
I
T
V
F
L
T
V
-----
A
V
G
M
V
--
L
A
--
C
L
-------
V
Q
-----------
W
E
--------
A
-------
L
R
G
K
A
V
Y
R
V
L
L
I
L
P
Y
A
---
V
P
S
F
I
S
----
I
L
I
F
----
K
G
------
L
F
N
------
Q
----------------
S
FGEINMMLSALFGVKPAWFSDPTTA
R
T
M
L
I
I
V
N
T
W
L
G
Y
P
Y
M
M
I
L
C
-------
M
G
L
-
L
K
A
I
---------------
P
D
D
L
Y
E
A
S
A
M
D
----
G
A
G
P
F
--
Q
N
F
F
K
I
T
L
P
L
L
I
K
P
L
-
T
P
L
M
I
A
S
-----
F
A
F
N
F
N
N
F
V
L
I
-
Q
L
L
T
N
G
G
P
D
RLGTTTPAG
Y
T
D
L
L
V
N
Y
T
Y
R
I
A
F
E
GGG
G
--
Q
-
D
-
F
G
L
A
A
A
I
A
T
L
I
F
L
L
V
G
A
L
A
I
--------------------------------------------------------------------------
24
Fugue
63.79
14%
-105
- C6 -
4TQU
-
?
N:
[2-284]
------------------------------------------------------------------------------------------------
L
A
T
P
F
Y
S
R
S
D
R
I
F
G
I
V
N
A
V
L
L
G
--
I
F
A
L
C
A
L
Y
P
I
I
Y
I
F
---
S
M
S
I
---------------------------------------
S
S
G
A
A
V
T
Q
G
R
-----
V
F
L
L
--
P
V
D
I
D
F
S
A
Y
G
R
V
L
H
----------------------------------
D
K
-----
L
F
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T
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Y
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N
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I
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Y
---------
T
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F
G
V
V
T
S
L
-----
I
F
I
V
P
GA
Y
A
--
L
S
-------
K
P
-----------
R
I
--------
R
-------
G
R
R
V
F
G
F
I
I
A
F
T
M
W
F
N
AGM
I
P
F
F
L
N
----
M
R
D
L
----
G
L
------
L
--------
D
----------------
N
-------------------------
R
F
G
I
L
I
G
F
A
C
N
---
A
F
N
I
I
L
-------
M
R
N
Y
F
E
S
I
---------------
S
A
S
F
E
E
A
A
R
M
D
----
G
A
N
D
L
--
Q
I
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W
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Y
I
P
L
A
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P
A
L
A
T
I
T
L
L
C
A
-----
I
S
R
W
N
G
Y
F
W
A
M
-
V
L
L
R
A
E
E
K
I
---------
P
L
Q
V
Y
L
K
K
T
I
V
D
L
N
V
---
N
--
E
-
E
F
A
G
A
L
L
T
N
S
Y
S
M
E
T
V
V
G
A
I
I
V
-------------
M
S
I
I
P
V
I
I
V
Y
P
V
V
Q
K
Y
FTK------------------------------------------
2
PsiBlast_PDB
61.74
23%
-114
- C6 -
3TUI
-
METI_ECOLI
A:
[17-141]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
M
T
F
V
S
G
-----
F
F
G
F
V
--
I
G
--
L
P
-------
V
G
V
L
L
Y
V
T
RPGQI
I
A
--------
N
-------
A
K
L
Y
R
T
V
S
A
I
V
N
I
F
R
S
---
I
P
F
I
I
L
----
L
V
W
M
I
P
F
T
R
V
------
I
V
G
------
T
SI--------------
G
-------------------------
L
Q
A
A
I
V
P
L
T
V
G
A
A
P
F
I
A
R
M
V
-------
E
N
A
L
L
E
I
----------------
P
T
G
L
I
E
A
S
R
A
M
----
G
A
T
P
M
--
Q
I
V
R
K
V
L
L
P
E
A
L
P
G
L
-
V
N
A
A
T
I
T
-----
L
I
T
L
V
G
Y
S
A
M
G
-
G
A
V
G
A
G
G
L
G
---------
Q
I
G
Y
Q
Y
G
Y
I
G
Y
N
A
T
V
---
M
--
N
-
T
V
L
V
L
L
V
I
L
V
Y
L
I
Q
F
A
G
D
R
I
V
R
-------------
A
V
T
R
---------------------------------------------------------
3
PsiBlast_PDB
60.26
23%
-111
- C6 -
3TUZ
-
METI_ECOLI
A:
[17-141]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
M
T
F
V
S
G
-----
F
F
G
F
V
--
I
G
--
L
P
-------
V
G
V
L
L
Y
V
T
RPGQI
I
A
--------
N
-------
A
K
L
Y
R
T
V
S
A
I
V
N
I
F
R
S
---
I
P
F
I
I
L
----
L
V
W
M
I
P
F
T
R
V
------
I
V
G
------
T
SI--------------
G
-------------------------
L
Q
A
A
I
V
P
L
T
V
G
A
A
P
F
I
A
R
M
V
-------
E
N
A
L
L
E
I
----------------
P
T
G
L
I
E
A
S
R
A
M
----
G
A
T
P
M
--
Q
I
V
R
K
V
L
L
P
E
A
L
P
G
L
-
V
N
A
A
T
I
T
-----
L
I
T
L
V
G
Y
S
A
M
G
-
G
A
V
G
A
G
G
L
G
---------
Q
I
G
Y
Q
Y
G
Y
I
G
Y
N
A
T
V
---
M
--
N
-
T
V
L
V
L
L
V
I
L
V
Y
L
I
Q
F
A
G
D
R
I
V
R
-------------
A
V
T
R
---------------------------------------------------------
1
PsiBlast_PDB
58.07
23%
-105
- C6 -
3DHW
-
METI_ECOLI
A:
[17-141]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
M
T
F
V
S
G
-----
F
F
G
F
V
--
I
G
--
L
P
-------
V
G
VLLYVTRPGQI
I
A
--------
N
-------
A
K
L
Y
R
T
V
S
A
I
V
N
I
F
R
S
---
I
P
F
I
I
L
----
L
V
W
M
I
P
F
T
R
V
------
I
V
G
------
T
SI--------------
G
-------------------------
L
Q
A
A
I
V
P
L
T
V
G
A
A
P
F
I
A
R
M
V
-------
E
N
A
L
L
E
I
----------------
P
T
G
L
I
E
A
S
R
A
M
----
G
A
T
P
M
--
Q
I
V
R
K
V
L
L
P
E
A
L
P
G
L
-
V
N
A
A
T
I
T
-----
L
I
T
L
V
G
Y
S
A
M
G
-
G
A
V
G
A
G
G
L
G
---------
Q
I
G
Y
Q
Y
G
Y
I
G
Y
N
A
T
V
---
M
--
N
-
T
V
L
V
L
L
V
I
L
V
Y
L
I
Q
F
A
G
D
------------------------------------------------------------------------------
19
Fugue
57.47
10%
-78
- C5 -
1GC5
1
GLKA_THELN
A:
[1-467]
MKES
L
K
D
R
I
R
L
W
K
R
L
Y
V
N
A
F
E
N
A
L
N
A
IPNVK
G
V
L
L
A
Y
N
T
N
I
D
A
I
K
YLD
A
D
D
L
E
K
R
V
T
E
K
GK
E
K
V
F
E
I
I
E
N
P
P
E
K
ISS
I
E
E
L
L
G
G
I
L
R
S
I
K
L
G
K
A
M
E
W
F
V
E
S
E
E
V
R
R
Y
L
R
E
W
G
W
D
E
L
R
I
GG
Q
A
G
I
M
A
N
L
L
G
G
V
Y
R
---
I
P
T
I
V
---
H
V
P
Q
N
P
K
L
Q
A
E
L
F
V
D
G
P
I
Y
V
P
V
F
E
-------
G
N
K
L
K
L
V
H
P
K
D
A
I
A
EEEEL
I
H
Y
I
--
Y
E
F
P
R
G
F
Q
V
F
D
V
Q
A
--
P
R
E
N
R
F
---
I
A
N
A
D
D
Y
N
------------
A
---------------
R
V
Y
M
R
R
---------
E
F
R
E
G
F
E
E
I
-----
T
R
N
V
E
--
L
A
--
I
I
-------
S
G
-----------
L
Q
VLKEYYPD
G
-------
T
T
Y
K
D
V
L
D
R
V
E
S
H
L
N
I
---
L
N
R
Y
N
V
----
K
S
H
F
----
E
F
AYTAN
R
R
V
R
------
E
----------------
A
-------------------------
L
V
E
L
L
P
K
F
T
S
V
G
L
N
--
E
V
E
L
-------
A
S
I
M
E
I
I
G
---------------
D
E
E
L
A
K
E
V
L
E
G
----
H
I
F
S
V
--
I
D
A
M
N
V
L
M
D
E
T
G
----
I
E
R
I
H
F
H
-----
T
Y
G
---
Y
Y
L
A
L
-
T
Q
Y
R
G
E
E
V
R
---------
D
A
L
L
F
A
S
L
A
A
A
A
K
A
M
---
K
--
G
-
N
L
E
R
I
E
Q
I
R
D
A
L
S
V
P
T
N
E
R
A
I
V
-------------
L
E
E
E
L
E
K
E
F
T
E
F
E
N
G
L
I
D
M
VD
R
Q
L
A
F
V
P
T
K
I
V
A
SPKSTVG
I
G
D
T
I
S
S
S
A
F
V
S
E
F
G
M
R
K
R--
21
Fugue
57.08
10%
-81
* C5 *
1L2L
-
GLKA_PYRHO
A:
[7-457]
-----------W
E
S
L
Y
E
K
A
L
D
K
V
E
A
S
IRKVR
G
V
L
L
A
Y
N
T
N
I
D
A
I
K
YLK
R
E
D
L
E
K
R
I
E
K
V
G
K
E
E
V
L
R
Y
S
E
E
L
P
K
E
IET
I
P
Q
L
L
G
S
I
L
W
S
I
K
R
G
K
A
A
E
L
L
V
V
S
R
E
V
R
E
Y
M
R
K
W
G
W
D
E
L
R
M
G
G
Q
V
G
I
M
A
N
L
L
G
G
V
Y
G
---
I
P
V
I
A
---
H
V
P
Q
L
S
E
L
Q
A
S
L
F
L
D
G
P
I
Y
V
P
T
-------------
R
L
I
H
P
R
E
F
--EDC--
I
H
Y
I
--
Y
E
F
P
R
N
F
K
V
L
D
F
E
A
--
P
R
E
N
R
F
---
I
G
A
A
D
D
Y
---------------------------
N
P
I
L
Y
V
R
E
---------
E
W
I
E
R
F
E
E
I
-----
A
K
R
S
E
--
L
A
--
I
I
-------
S
G
-----------
L
H
PLTQE------------
N
H
G
K
P
I
K
L
V
R
E
H
L
K
I
---
L
N
D
L
G
I
----
R
A
H
L
----
E
F
AFTPD
E
V
V
R
------
L
----------------
E
-------------------------
I
V
K
L
L
K
H
F
Y
S
V
G
L
N
--
E
V
E
L
-------
A
S
V
V
S
V
M
G
---------------
E
K
E
L
A
E
R
I
I
S
K
----
D
P
A
D
P
--
I
A
V
I
E
G
L
L
K
L
I
K
E
T
G
-
V
K
R
I
H
F
H
-----
T
Y
G
---
Y
Y
L
A
L
-
T
R
E
K
G
E
H
V
R
---------
D
A
L
L
F
S
A
L
A
A
A
T
K
A
M
---
K
--
G
-
N
I
E
K
L
S
D
I
R
E
G
L
A
V
P
I
G
E
Q
G
L
E
-------------
V
E
K
I
L
E
K
E
F
S
L
R
-
D
G
I
G
S
I
ED
Y
Q
L
T
F
I
P
T
KGI
G
D
T
I
S
S
S
A
F
V
S
E
F
S
L
H-------------
22
Fugue
55.06
13%
-96
- C5 -
2E0N
1
?
B:
[6-245]
-------------------------------------------------------------------------
S
-----------
I
I
S
V
S
L
G
P
G
D
-
P
G
L
I
T
V
K
A
L
S
Q
L
R
E
A
---------
D
V
I
Y
Y
P
G
T
V
S
A
S
G
A
---
V
T
S
V
A
---
L
D
I
L
-----------
K
E
F
D
L
D
P
S
K
-------
L
R
G
M
L
---------------------------------------------------
V
P
------------
M
S
R
G
A
-----
A
E
A
S
Y
A
A
N
Y
A
S
M
---------
A
E
E
V
Q
A
G
R
R
-----
V
A
V
V
S
--
V
G
DG
G
F
-------
Y
S
-----------
T
A
--------
S
-------
A
I
I
E
R
A
R
R
D
G
L
D
-
C
S
M
---
T
P
--------------------------------------------------
G
-------------------------
I
P
A
F
I
A
A
G
S
A
A
G
M
P
L
A
L
Q
S
D
-------
S
V
L
V
L
A
Q
I
---------------
D
E
I
--------------------
G
E
L
E
R
A
L
V
T
H
S
T
V
V
-
V
M
K
L
S
T
V
RDE--
L
V
S
F
L
E
R
Y
A
K
P
-
F
L
Y
A
E
K
V
G
M
---------
A
G
E
F
I
T
M
E
V
D
A
L
R
S
R
---
A
--
I
-
P
Y
F
---------------
S
L
L
V
-------------
C
S
P
H
C
R
Q
S
T
L
S
P
F
A
-----------------------------------------------
4
PsiBlast_PDB
52.92
21%
-75
- C6 -
3TUJ
-
METI_ECOLI
A:
[9-140]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
V
R
G
V
W
E
T
L
A
M
---------
T
F
V
S
G
F
F
G
F
-----
V
I
G
L
P
--
V
G
--
V
L
L
Y
V
T
RPG
Q
I
-----------
I
A
--------
N
-------
A
K
L
Y
R
T
V
S
A
I
V
N
I
F
R
S
---
I
P
F
I
I
L
L
V
W
M
I
P
F
T
----
R
V
------
I
V
G
------
T
SI--------------
G
-------------------------
L
Q
A
A
I
V
P
L
T
V
G
A
A
P
F
I
A
R
M
V
-------
E
N
A
L
L
E
I
----------------
P
T
G
L
I
E
A
S
R
A
M
----
G
A
T
P
M
--
Q
I
V
R
K
V
L
L
P
E
A
L
P
G
L
-
V
N
A
A
T
I
T
-----
L
I
T
L
V
G
Y
S
A
M
G
-
G
A
V
G
A
G
G
L
G
---------
Q
I
G
Y
Q
Y
G
Y
I
G
Y
N
A
T
V
---
M
--
N
-
T
V
L
V
L
L
V
I
L
V
Y
L
I
Q
F
A
G
D
R
I
V
R
-------------
A
V
T
R
---------------------------------------------------------
27
Fugue
47.19
20%
-101
- C4 -
2QUO
1
A:
[4-126]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
E
I
L
D
L
A
A
A
T
E
R
L
N
L
T
--
D
A
--
L
N
-------
S
N
-----------
P
A
--------
G
-------
N
L
Y
D
W
R
S
S
N
S
Y
P
W
T
Q
K
---
L
N
L
H
L
T
----
I
T
A
T
----
G
Q
K
Y
R
---
I
L
A
------
S
----------------
K
-------------------------
I
V
D
F
N
I
Y
S
N
N
F
N
N
L
V
K
L
E
Q
S
L
G
DGV
K
D
H
Y
V
D
I
S
L
D
---------------
A
G
Q
Y
V
L
V
M
K
A
N
S
S
Y
S
G
N
Y
P
Y
--
S
I
L
F
Q
K
F
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
Fugue
46.90
16%
79
- C6 -
4XO2
-
GNSA_ECOLI
A:
[1-60]
------------------------------------------------------------------------------------------
M
N
I
E
E
L
K
K
Q
A
E
T
E
I
A
D
F
I
A
Q
K
I
A
E
L
N
K
N
--
T
G
K
----------------
E
V
S
---
E
I
R
F
T
A
R
E
K
M
T
G
L
E
S
Y
D
V
K
I
K
I
M
L
-------
E
H
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
Fugue
44.75
15%
150
- C6 -
3BBP
-
GCC2_HUMAN
D:
[29-66]
----------------------------------------------------------------------
K
S
A
D
-----------
H
L
N
G
L
L
R
E
T
E
A
T
N
A
I
L
M
E
Q
I
K
L
L
K
S
E
I
R
R
L
E
R
N
--
Q
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
40.66
41%
-153
- C6 -
4CZ9
-
?
A:
[78-108]
--------------------------------------------------------------------------------------------------------------
S
W
R
L
L
K
K
N
--
M
P
T
I
V
T
L
D
T
I
G
L
I
L
---
T
A
L
I
A
---
G
F
I
F
K
V
V
F
N
S
S
F
L
L
G
F
L
F
G
A
I
I
G
A
-------
T
D
P
A
T
L
I
P
L
F
R
Q
Y
R
-----
V
K
Q
D
--
I
E
T
V
I
V
T
E
S
I
F
N
D
P
--
L
G
I
V
L
T
---
L
I
A
I
S
M
L
V
------------
P
G
Y
G
G
-----
G
I
F
S
T
L
S
E
K
L
G
I
---------
Y
A
G
G
V
I
Y
F
L
-----
Y
N
V
S
V
--
S
I
--
S
L
-------
G
I
-----------
F
L
--------
G
-------
I
L
G
Y
K
F
I
K
R
T
G
I
F
D
F
P
---
E
I
E
A
F
S
----
L
S
L
A
----
F
L
------
G
F
F
------
I
----------------
G
-------------------------
E
R
L
D
A
S
G
Y
L
V
A
T
V
T
G
I
V
L
G
N
-------
Y
K
L
L
K
P
R
E
---------------
N
I
R
I
L
K
R
L
Q
R
A
----
I
E
K
E
V
--
H
F
N
D
T
L
A
A
L
A
T
I
F
I
F
-
V
L
L
G
A
E
M
-----
N
L
E
V
I
W
S
N
L
G
K
-
G
L
L
V
A
L
G
V
M
---------
I
L
A
R
P
L
A
T
L
P
L
L
K
W
W
---
N
--
F
-
R
E
Y
L
F
I
A
L
E
G
P
R
G
V
V
P
S
A
L
A
S
L
-------------
P
L
S
L
A
L
K
Y
K
S
P
L
L
T
V
H
---------------------------------------------
5
PsiBlast_PDB
40.08
32%
95
- C2 -
2KUT
-
?
A:
[2-62]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
L
-------
P
I
T
L
S
K
E
T
P
F
E
G
E
E
-----
I
T
V
S
--
A
R
V
T
N
R
G
A
A
E
A
H
N
V
--
P
V
A
V
Y
L
G
NP
A
Q
G
G
V
E
I
G
------------
R
D
T
I
S
-----
R
I
P
V
G
G
T
G
L
A
R
V
---------
Q
W
K
A
T
R
K
L
A
-----
G
R
A
A
N
--
P
G
--
V
P
-------
V
Y
-----------
A
V
--------
V
-------
D
P
D
N
R
V
A
E
S
D
K
A
N
N
V
F
---
S
R
I
V
K
V
----
L
E
H
H
----
H
H
------
H
H
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
38.86
41%
-140
- C6 -
4CZ8
-
?
A:
[78-108]
--------------------------------------------------------------------------------------------------------------
S
W
R
L
L
K
K
N
--
M
P
T
I
V
T
L
D
T
I
G
L
I
L
---
T
A
L
I
A
---
G
F
I
F
K
V
V
F
N
S
S
F
L
L
G
F
L
F
G
A
I
I
G
A
-------
T
D
P
A
T
L
I
P
L
F
R
Q
Y
R
-----
V
K
Q
D
--
I
E
T
V
I
V
T
E
S
I
F
N
D
P
--
L
G
I
V
L
T
---
L
I
A
I
S
M
L
V
------------
P
G
Y
G
G
-----
G
I
F
S
T
L
S
E
K
L
G
I
---------
Y
A
G
G
V
I
Y
F
L
-----
Y
N
V
S
V
--
S
I
--
S
L
-------
G
I
-----------
F
L
--------
G
-------
I
L
G
Y
K
F
I
K
R
T
G
I
F
D
F
P
---
E
I
E
A
F
S
----
L
S
L
A
----
F
L
------
G
F
F
------
I
----------------
G
-------------------------
E
R
L
D
A
S
G
Y
L
V
A
T
V
T
G
I
V
L
G
N
-------
Y
K
L
L
K
P
R
E
---------------
N
I
R
I
L
K
R
L
Q
R
A
----
I
E
K
E
V
--
H
F
N
D
T
L
A
A
L
A
T
I
F
I
F
-
V
L
L
G
A
E
M
-----
N
L
E
V
I
W
S
N
L
G
K
-
G
L
L
V
A
L
G
V
M
---------
I
L
A
R
P
L
A
T
L
P
L
L
K
W
W
---
N
--
F
-
R
E
Y
L
F
I
A
L
E
G
P
R
G
V
V
P
S
A
L
A
S
L
-------------
P
L
S
L
A
L
K
Y
K
S
P
L
L
T
V
H
---------------------------------------------