@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv0017c: (2016-04-18 )
MTTRLQAPVAVTPPLPTRRNAELLLLCFAAVITFAALLVVQANQDQGVPWDLTSYGLAFLTLFGSAHLAIRRFAPYTDPLLLPVVALLNGLGLVMIHRLDLVDNEIGEHRHPSANQQMLWTLVGVAAFALVVTFLKDHRQLARYGYICGLAGLVFLAVPALLPAALSEQNGAKIWIRLPGFSIQPAEFSKILLLIFFSAVLVAKRGLFTSAGKHLLGMTLPRPRDLAPLLAAWVISVGVMVFEKDLGASLLLYTSFLVVVYLATQRFSWVVIGLTLFAAGTLVAYFIFEHVRLRVQTWLDPFADPDGTGYQIVQSLFSFATGGIFGTGLGNGQPDTVPAASTDFIIAAFGEELGLVGLTAILMLYTIVIIRGLRTAIATRDSFGKLLAAGLSSTLAIQLFIVVGGVTRLIPLTGLTTPWMSYGGSSLLANYILLAILARISHGARRPLRTRPRNKSPITAAGTEVIERV
Atome Classification :
(20 SA)
----------------------.........10........20........30........-40.....-----..-.50........60.........70.......----.80----.......--.-------90........--100.....--..110...-.---.-------..120.......130.......140......--.-150-------.......160---.........170.......180.......190------.......200....-----------..--.210...------.---...220---------------.........-230------------.......240.---.....--.250....-----------...260----------.........270-.......280-------.---........290.......300.----.-----.....310...-----....-----320..-.....330.......340----........350.......360...------------------..--...370--.......380.......390...---.--...400.--......410........420.......430-....---....440.......-450------....-....460--.......----------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----------------------MTTRLQA
P
V
AVTPPLPTRRN
A
E
L
L
L
L
C
F
A
A
V
I
T
F
A
A
L
L
V
-
V
QANQDQ-----GV-PW
D
L
T
S
Y
G
L
A
F
L
-
T
L
FGSA
H
L
A
I
R
RFAPYTD----
P
L
L
----
L
P
V
V
A
L
L--N-------
G
L
G
L
V
M
I
H
R
L--DLVD
N
E
I
G--EHRHPSA
N
-
Q
---
Q
-------
M
L
W
T
L
V
G
V
A
A
F
A
L
V
V
T
F
L
K
D
H
R
Q
L
A
R
Y
G
Y
I
C
--
G
-
L
A
G
-------
L
V
F
L
A
V
P
A
-----
L
L
P
A
A
LSEQNG
A
K
I
W
I
RLPGFSIQ
P
A
E
F
S
K
I
L
------
L
L
I
F
F
S
A
V
L
V
A
KRG-----------L
F
--
T
S
AG
K
H
L
------
L
---GMTL-----------------PRPR
D
L
A
P
L
-
L
A
A
------------
W
V
I
S
V
G
V
M
V
F
E
---KDLG
A
--
S
L
L
L
Y
T
S
F
-----------
L
V
V
V
------------
Y
L
ATQR
F
S
W
V
V
I
-
G
L
T
L
F
A
A
G
---------
T
---
L
V
A
Y
F
I
F
E
H
V
R
L
R
V
Q
T
W
LDPFA----D-----PDGT
G
Y
Q
I
V
Q
S
-----
L
F
S
F-----ATGG
I
-
F
GTGLGNGQPDTVPAAS-----T
D
F
I
I
A
A
F
G
EEL
G
L
V
G
L
T
A
-
I
L
M
L
------------------
Y
T
--
I
V
I
I
R
G
--
L
R
T
A
I
A
T
R
D
S
F
G
K
L
L
A
A
GLSS
T
L
---
A
--
I
Q
L
F
I
V
V--GG
V
T
R
L
I
P-LTGLT
T
P
W
M
SYG
G
S
S
L
L
A
N
Y
--
I
L
L
A
---
I
L
A
R
I
SHGARRPLR-TR-------PRNK-SPIT
A
A
G
--
T
E
V
I
ERV----------------
29
Fugue
88.47
22%
-110
- C4 -
4P5F
1
?
A:
[8-374]
----------------------
L
T
-------------
P
T
E
A
A
V
L
R
E
L
R
L
H
R
P
Q
L
P
L
D
T
L
L
F
-
T
D
P
N
K
D
---------
P
D
D
V
V
T
Y
T
I
A
--------
K
Q
L
Q
A
D
G
F
L
R
L
T
D
----
V
V
V
T
L
G
D
A
D
M
R
S
Q
R
--
A
-------
Q
L
A
K
G
V
F
D
R
L
--
A
L
P
D
V
R
V
A
--
R
G
Q
D
---------------------------
Y
P
M
T
S
T
Q
A
R
E
H
S
K
------------------------
F
L
A
E
G
A
-----
A
L
R
A
A
P
D
A
V
H
T
D
G
V
R
A
M
C
E
R
L
A
T
S
P
H
K
L
G
M
V
V
------
I
------------------------------
A
G
M
T
D
------
A
---
S
A
L
L
-----------------
A
E
A
G
D
L
V
R
E
-
K
V
A
------------
S
I
T
I
M
G
G
I
D
P
A
---
R
D
A
D
G
--
L
V
Q
P
D
T
R
A
-----------
Y
N
N
A
------------
T
--------------
D
I
H
A
A
R
---------
A
---
L
Y
R
R
A
Q
Q
L
G
I
P
L
R
I
L
T
------------------------
K
E
A
-----
A
Y
K
A
-----
A
V
P
P
A
-
F
Y
E
G
I
A
R
N
G
------------------
H
P
V
G
E
Y
L
R
D
V
Q
K
N
A
-
L
K
G
L
------------------
W
E
--
G
I
Q
-
A
N
--
L
I
P
G
L
D
T
A
W
F
F
R
T
F
V
A
G
A
L
S
-----------
F
D
A
I
W
--
P
Q
V
T
K
L
-----------------
N
L
Y
D
P
L
--
T
L
L
A
---
A
L
P
G
T
A
R
L
L
F
Q
P
T
P
-
M
H
-------
R
E
G
A
-
S
P
V
E
H
V
G
--
H
A
E
V
V
R
P
E
K
A
R
L
L
L
S
A
L
A
K
A
A
L
V
32
Fugue
85.72
16%
-110
- C2 -
3M6A
1
LON1_BACSU
A:
[7-531]
TGEVQ
T
L
T
E
K
I
E
EAGMPDHVK
E
T
A
L
K
E
L
N
R
Y
E
K
I
P
S
S
S
A
E
S
S
V
I
R
N
Y
I
D
W
L
V
A
L
P
W
T
D
E
T
D
-
D
K
L
D
L
K
E
-----
A
G
R
L
L
D
E
E
H
H
G
L
E
K
V
-
K
E
R
I
L
E
Y
L
A
V
Q
K
L
---
T
K
----
S
L
K
----
G
P
I
L
C
L
A
--
G
PPGVG
K
T
S
L
A
K
S
I
A
K
S
L
G
R
K
F
V
R
I
S
L
G
--
G
R
I
I
Q
G
M
K
-
K
---
A
GKLN
P
V
F
L
L
D
E
I
D
K
M
S
A
M
L
E
V
L
D
P
E
Q
N
S
S
F
S
D
H
Y
I
E
E
T
--
F
D
L
S
K
-------
V
L
F
I
A
T
A
N
-----
N
L
A
T
I
P
G
P
L
R
D
R
M
E
I
I
N
I
A
G
Y
T
---
E
I
E
K
L
E
I
------
V
K
D
H
L
L
P
K
Q
I
K
E
H
G
-----------
L
K
--
K
S
N
---------------
L
Q
L
-----------------
R
-
D
Q
A
I
L
D
I
-
I
R
Y
------------
Y
T
R
E
A
G
V
R
S
L
E
---
R
Q
L
A
A
--
I
C
R
K
A
A
K
A
-----------
I
V
A
E
--------------
E
R
K
R
I
T
V
T
E
K
-
N
L
Q
D
F
I
G
K
---------
R
---
I
F
R
Y
G
Q
A
E
T
E
D
Q
V
G
V
V
T
G
L
A
Y
T
----
T
-----
V
G
G
D
T
L
S
I
E
V
S
-----
L
S
P
G
-----
K
G
K
L
I
-
L
T
G
K
L
G
D
V
M
R
E
S
A
Q
A
A
F
-----
S
--
Y
V
R
S
K
T
E
E
L
G
I
E
P
D
F
H
-
E
K
Y
D
------------------
I
H
--
I
H
V
P
E
G
----
A
V
P
K
D
G
P
A
A
G
I
T
M
A
T
A
L
V
S
A
L
T
GR
A
--
V
S
R
E
V
G
M
--
T
G
---
E
I
T
-
L
R
G
R
V
L
P
I
G
G
L
K
E
K
A
L
G
A
H
R
A
G
L
T
T
I
---
I
A
P
K
D
N
E
K
D
I
E
D
I
P
-
E
S
-------
V
R
E
G
-
L
T
F
I
L
A
S
H
L
D
E
V
L
E
H
A
L
V--------------
31
Fugue
82.87
20%
-124
- C4 -
4ZOX
-
SQT1_YEAST
A:
[53-431]
----------------------
M
S
N
N
-------
S
L
T
Y
F
D
K
H
T
D
S
V
F
A
I
G
H
H
P
N
L
P
---
L
V
C
-
T
G
G
G
D
N
L
-----
A
H
-
L
W
T
S
H
S
Q
P
P
K
F
A
G
T
L
T
G
Y
G
E
S
V
I
S
--
C
S
F
T
S
----
E
G
G
----
F
L
V
T
A
D
M
--
S
-------
G
K
V
L
V
H
M
G
Q
--------------------
K
-
G
---
G
-------
A
Q
W
K
L
A
S
Q
M
Q
E
V
E
E
I
V
W
L
K
T
H
P
T
I
A
R
T
F
A
F
G
--
A
-
T
D
G
--------------
S
-----
V
W
C
Y
Q
I
N
E
Q
D
G
-
S
L
E
Q
L
M
S
G
F
V
H
Q
Q
D
----------------------
C
S
M
G
-----------
E
F
I
N
T
D
K
G
E
N
T
------
L
---
E
L
V
T
-----------------
C
S
---
L
D
S
T
-
I
V
A
------------
W
N
C
F
T
G
Q
Q
L
F
K
I
T
Q
A
E
I
K
G
--
L
E
A
P
W
I
S
L
-----------
S
L
A
P
------------
E
T
L
T
K
G
N
S
G
V
V
A
-
C
G
S
--
N
N
G
---------
L
---
L
A
V
I
N
----------------
C
----
N
-----
N
G
G
A
I
L
H
L
S
T
V
-----
I
-------------------
E
L
K
P
E
Q
D
E
L
D
A
S
-----
I
E
S
I
S
W
S
S
K
F
S
L
M
A
I
G
L
V
C
G
E
I
L
L
------------------
Y
D
--
T
S
A
W
R
---
V
R
H
K
F
V
L
E
D
S
V
T
K
L
M
F
D
N
D
-----------
D
L
F
A
S
C
IN
G
K
V
Y
Q
F
N
A
-
R
T
G
-
Q
E
K
F
V
C
V
G
H
N
M
G
V
L
D
F
--
I
L
L
H
---
P
V
A
N
T
G
T
E
Q
K
R
K
V
I
-
T
A
-------
G
D
E
--------
G
--
V
S
L
V
F
E
V
P
N--------------
26
Fugue
81.57
18%
-115
* C7 *
2OCC
-
COX1_BOVIN
A:
[1-514]
----------------------
M
F
I
N
R
W
L
F
---
S
T
N
H
K
D
I
G
T
L
Y
L
L
F
G
A
W
A
G
M
V
G
T
A
L
S
L
L
-
I
R
A
E
L
G
Q
PGTLL
G
-------------------
D
D
Q
I
Y
N
V
V
V
T
A
H
A
F
----
V
M
I
----
F
F
M
V
M
P
I
MI
G
-------
G
F
G
N
W
L
V
P
L
M
--------
I
G
AP
D
M
A
F
P
R
M
N
-
N
---
M
-------
S
F
W
L
L
P
P
S
F
L
L
L
L
A
S
S
M
V
E
---
A
G
A
G
T
G
W
T
V
YP
P
-
L
A
G
NLAHAGA
S
V
D
L
T
I
F
S
-----
L
H
L
A
G
V
S
S
I
L
G
A
I
N
F
I
T
T
I
-
I
N
M
K
P
P
A
M
S
Q
Y
Q
------
T
P
L
F
V
W
S
V
M
I
T
A
V
L
-----------
L
L
--
L
S
L
P
V
L
A
------
A
---
G
I
T
M
L
L
T
D
R
NLNTTFFDPAGG
G
D
P
I
L
Y
Q
H
L
-
F
W
F
------------
F
G
H
P
E
V
Y
I
L
I
L
---
P
G
F
G
M
--
I
S
H
I
V
T
Y
Y
S
GKKEPFG
Y
M
G
M
V
W
A
------------
M
M
S
I
G
F
L
G
F
I
V
W
-
A
H
H
M
F
T
V
G
MD
V
D
T
R
A
Y
F
T
---
S
A
T
M
I
I
A
I
P
T
G
V
K
V
F
S
W
L
A
T
L
H
GGNI
K
-----
W
S
P
A
M
M
W
A
L
G
F
-----
I
F
L
F
-----
T
V
G
G
L
-
T
G
I
V
L
A
N
S
S
L
D
I
V
L
H
-
D
-----
T
Y
Y
V
V
A
H
F
H
Y
V
L
S
M
G
A
V
F
A
-
I
M
G
G
------------------
F
V
H
W
F
P
L
F
S
G
--
Y
T
L
N
D
T
W
A
K
I
H
F
A
I
M
F
V
G
V
N
M
T
F
---
F
--
P
Q
H
F
L
G
L
--
S
G
M
P
R
R
Y
S
D
Y
P
D
A
Y
T
M
W
N
T
I
S
S
M
G
S
F
I
S
L
--
T
A
V
M
---
L
M
V
F
I
I
W
E
A
F
A
S
K
R
E
V
L
----------
T
-
V
D
L
T
T
T
N
--
L
E
W
L
N
G
C
PPPYHTFE
E
P
T
Y
V
N
LK
33
Fugue
75.07
15%
-95
* C4 *
3AQB
3
HEXB_MICLU
B:
[5-325]
-------------------------------------------
S
Y
K
A
F
L
N
P
Y
I
I
E
V
E
K
R
L
Y
-
E
C
I
Q
S
D
S
-------------------
E
-
T
I
N
K
A
A
H
H
I
L
S
S
G
G
K
R
V
R
----
P
M
F
----
V
L
L
S
G
F
L
--
N
-------
D
-----------------------
T
Q
K
D
D
L
-
I
---
R
-------
T
A
V
S
L
E
L
V
H
M
A
S
L
V
H
D
D
Y
I
D
N
S
D
M
R
R
G
N
T
--------------------
S
V
H
I
-----
A
F
D
K
D
T
A
I
R
T
G
H
F
L
L
A
R
--
A
L
Q
N
I
A
T
I
N
N
S
K
F
------
H
Q
I
F
S
K
T
I
L
E
V
C
F
G
-----------
E
F
--
D
Q
M
A
--------------------------------------------------------------------------
D
R
F
N
--
Y
P
V
S
F
T
A
Y
-----------
L
R
R
I
------------
N
R
K
T
----------
A
I
L
I
E
A
S
---------
C
---
H
L
G
A
L
S
S
Q
-
L
D
E
Q
S
T
Y
H
I
K
Q
F
G
----
H
-----
C
I
G
M
S
Y
Q
I
I
D
D
-----
I
L
D
Y
TSDEA
T
L
G
K
P
-
V
G
S
D
I
R
N
G
H
I
-------------------------------------------------------
T
--
Y
P
L
M
A
A
--
I
A
N
L
K
E
Q
D
D
D
K
L
E
A
V
V
K
H
L
T
S
T
S
---
D
--
D
E
V
Y
Q
Y
I
--
V
S
Q
V
K
Q
Y
G
-
I
E
P
A
E
L
L
S
R
K
Y
G
D
K
A
K
Y
H
L
S
--
Q
L
--------------------
Q
D
-------
S
N
I
K
-
D
Y
L
E
E
I
H
--
E
K
M
L
K
R
V
Y---------------
30
Fugue
71.19
21%
-117
- C- -
3WPU
2
?
A:
[3-540]
----------------------
G
L
Q
D
G
P
E
P
T
I
H
T
Q
Q
A
Y
A
P
E
D
D
------
F
T
A
K
W
T
R
A
D
A
R
Q
-
L
Q
R
M
S
D
P
-----
T
A
-
P
S
R
E
N
S
M
P
------------------
A
S
V
T
M
----
P
T
V
----
P
Q
D
F
P
D
M
--
S
-------
N
E
Q
V
W
V
W
D
T
W
--
P
L
T
D
E
D
-----
A
N
Q
Y
S
V
N
G
W
---
E
-------
I
I
F
S
L
V
A
D
R
N
L
G
-----
F
D
D
R
H
V
F
A
K
I
G
Y
F
Y
--
R
-
P
A
G
-------
V
P
A
A
E
R
P
E
NGGWT
Y
G
G
L
V
F
K
E
G
V
T
G
Q
I
F
-
E
D
Q
S
F
S
H
Q
T
Q
W
S
G
S
A
R
V
S
KNGE
I
K
L
F
F
T
D
V
A
F
Y
R
N
S
DGTNI
K
P
Y
D
P
R
I
A
--
L
S
V
G
K
V
K
------
A
N
KK
G
V
T
L
-----------------
T
G
F
N
K
V
T
D
L
-
L
Q
A
DGTYYQTGAQNE
F
F
N
F
R
D
P
F
T
F
E
D
P-
A
H
P
G
E
--
T
F
M
V
F
E
G
N
-----------
S
A
M
Q
RET
A
T
C
N
EADLG
Y
R
Q
G
D
P
Y
A
E
T
V
D
-
D
V
N
A
S
G
A
T
---------
Y
Q
I
G
N
V
G
L
A
K
A
K
N
K
Q
L
T
E
W
E
F
L
P
P
I
L
----
S
ANCVT
D
Q
T
E
R
P
Q
I
Y
F
K
DG
K
S
Y
L
F
T
I
-----
S
H
R
G
T
-
F
A
A
G
L
D
G
--
P
E
G
V
Y
G
F
V
G
DGIR
S
D
Y
Q
P
L
N
G
G
S
G
L
A
L
G
N
P
T
N
-
L
N
F
L
GGQPFAPDFNQHPGHFQA
Y
S
--
H
Y
V
M
P
G
G
L
V
Q
S
F
I
D
T
I
G
T
H
D
D
F
V
R
G
G
---
T
L
---
A
P
T
V
K
M
D
I
G
V
--
G
G
D
P
T
K
T
A
-
V
D
Y
S
Y
G
S
E
G
L
G
G
W
A
D
I
P
A
N
K
--
H
L
F
T
N
GK
F
G
V
A
V
S
D
E
A
A
Q
K
I
R
-
K
I
L
G
S
K
F
D
D
Y
L
D
G
-
K
P
V
S
A
T
V
--
R
A
L
I
E
K
L
L
A
Q
Y------------
34
Fugue
68.02
12%
-77
- C4 -
1WMW
-
?
A:
[1-328]
---------------------M
V
P
A
P
E
A
I
R
Q
A
L
Q
E
R
L
L
A
R
L
D
H
P
------
D
P
L
Y
R
D
L
L
Q
D
Y
-
P
R
R
G
G
K
M
----------------------
L
R
G
L
L
T
V
Y
S
A
L
A
H
G
A
P
L
----
E
A
G
----
L
E
A
A
T
A
L
--
E
-------
L
F
Q
N
W
V
L
V
H
D
--
D
I
E
D
G
S
E
E
--
R
R
G
R
P
A
L
H
-
R
LHP
M
-------
P
L
A
L
N
A
G
D
A
M
H
A
E
M
W
G
L
L
A
E
G
L
A
-------------
R
G
-------
L
F
P
P
E
V
L
L
-----
E
F
H
E
V
V
R
R
T
A
Y
G
Q
H
L
D
L
L
W
T
L
G
G
T
F
D
L
R
P
E
D
Y
------
F
R
M
V
A
H
K
A
-----------------------------------------------------------------
A
Y
Y
-
T
A
V
------------
A
P
L
R
L
G
A
L
L
A
G
---
K
T
---------------------------------------------------------------------------------------
P
P
A
A
Y
E
E
G
G
----
L
-----
R
L
G
T
A
F
Q
I
V
D
D
-----
V
L
N
L
-----
E
G
G
E
A
-
Y
G
K
E
R
A
G
D
L
Y
E
G
---------------------------------
K
------------------
R
T
--
L
I
L
L
R
F
--
L
E
E
A
P
P
E
E
R
A
R
A
L
A
L
L
A
L
P
R
E
A
----------------
K
P
E
A
E
V
G
W
-
L
L
E
R
L
L
A
S
R
A
L
A
W
A
K
A
E
A
K
R
--
L
Q
A
E
---
G
L
A
L
L
E
A
A
F
Q
D
L
---
P
G
-------
K
E
A
L
-
D
H
L
R
G
L
L
--
A
A
L
V
E
R
-----------------
5
PsiBlast_PDB
64.78
28%
-86
- C6 -
3IKO
-
NU145_YEAST
B:
[290-424]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
I
E
Q
I
F
------
L
Y
L
L
L
N
D
V
V
R
A
S
K
L
-----------
A
I
--
E
S
K
N
G
H
L
S
V
L
I
S
Y
L
---
G
S
N
D
-----------------
P
R
I
R
D
L
A
E
L
Q
L
Q
K
------------
W
--
S
T
G
G
C
S
I
D
---
K
N
I
S
K
I
Y
K
L
L
S
G
S
P
F
EG---------
L
F
S
L
------------
K
E
L
E
S
E
F
S
W
L
C
L
L
N
L
T
L
-
C
Y
G
---------
Q
---
I
D
E
Y
S
L
E
S
L
V
Q
S
H
L
D
K
F
S
L
P
Y
D
----
D
-----
P
I
G
V
I
F
Q
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
64.78
28%
-88
- C6 -
3BG0
-
NU145_YEAST
B:
[290-424]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
I
E
Q
I
F
------
L
Y
L
L
L
N
D
V
V
R
A
S
K
L
-----------
A
I
--
E
S
K
N
G
H
L
S
V
L
I
S
Y
L
---
G
S
N
D
-----------------
P
R
I
R
D
L
A
E
L
Q
L
Q
K
------------
W
--
S
T
G
G
C
S
I
D
---
K
N
I
S
K
I
Y
K
L
L
S
G
S
P
F
EG---------
L
F
S
L
------------
K
E
L
E
S
E
F
S
W
L
C
L
L
N
L
T
L
-
C
Y
G
---------
Q
---
I
D
E
Y
S
L
E
S
L
V
Q
S
H
L
D
K
F
S
L
P
Y
D
----
D
-----
P
I
G
V
I
F
Q
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
64.14
28%
-86
- C6 -
3BG1
-
NU145_YEAST
B:
[290-424]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
I
E
Q
I
F
------
L
Y
L
L
L
N
D
V
V
R
A
S
K
L
-----------
A
I
--
E
S
K
N
G
H
L
S
V
L
I
S
Y
L
---
G
S
N
D
-----------------
P
R
I
R
D
L
A
E
L
Q
L
Q
K
------------
W
--
S
T
G
G
C
S
I
D
---
K
N
I
S
K
I
Y
K
L
L
S
G
S
P
F
EG---------
L
F
S
L
------------
K
E
L
E
S
E
F
S
W
L
C
L
L
N
L
T
L
-
C
Y
G
---------
Q
---
I
D
E
Y
S
L
E
S
L
V
Q
S
H
L
D
K
F
S
L
P
Y
D
----
D
-----
P
I
G
V
I
F
Q
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
63.57
28%
-88
- C6 -
4XMM
-
B:
[291-486]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
I
E
Q
I
F
------
L
Y
L
L
L
N
D
V
V
R
A
S
K
L
-----------
A
I
--
E
S
K
N
G
H
L
S
V
L
I
S
Y
L
---
G
S
N
D
-----------------
P
R
I
R
D
L
A
E
L
Q
L
Q
K
------------
W
--
S
T
G
G
C
S
I
D
---
K
N
I
S
K
I
Y
K
L
L
S
G
S
P
F
EG---------
L
F
S
L
------------
K
E
L
E
S
E
F
S
W
L
C
L
L
N
L
T
L
-
C
Y
G
---------
Q
---
I
D
E
Y
S
L
E
S
L
V
Q
S
H
L
D
K
F
S
L
P
Y
D
----
D
-----
P
I
G
V
I
F
Q
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
63.15
28%
-88
- C6 -
4XMN
-
B:
[291-486]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
I
E
Q
I
F
------
L
Y
L
L
L
N
D
V
V
R
A
S
K
L
-----------
A
I
--
E
S
K
N
G
H
L
S
V
L
I
S
Y
L
---
G
S
N
D
-----------------
P
R
I
R
D
L
A
E
L
Q
L
Q
K
------------
W
--
S
T
G
G
C
S
I
D
---
K
N
I
S
K
I
Y
K
L
L
S
G
S
P
F
EG---------
L
F
S
L
------------
K
E
L
E
S
E
F
S
W
L
C
L
L
N
L
T
L
-
C
Y
G
---------
Q
---
I
D
E
Y
S
L
E
S
L
V
Q
S
H
L
D
K
F
S
L
P
Y
D
----
D
-----
P
I
G
V
I
F
Q
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
Fugue
63.08
10%
-75
- C4 -
2E8X
4
GGPPS_YEAST
B:
[4-340]
------------------------
N
K
M
E
A
K
I
D
E
L
I
N
N
D
P
V
W
--------
S
S
Q
N
E
S
L
I
S
K
P
Y
-
N
H
I
L
L
K
P
-----
G
-------------
K
-
N
F
R
L
N
L
I
V
Q
I
N
R
V
M
N
L
P
K
----
D
Q
L
----
A
I
V
S
Q
I
V
--
E
-------
L
L
H
N
S
S
L
L
I
D
--
D
I
E
D
N
A
P
L
--
R
R
G
Q
T
T
S
H
-
L
---
I
-------
F
G
-----------------------------------------------
V
P
S
T
-----
I
N
T
A
N
Y
M
Y
F
R
A
M
Q
L
V
S
Q
L
T
T
K
E
P
L
Y
H
N
L
I
T
I
F
------
N
E
E
L
I
N
L
H
R
G
Q
G
L
D
-----------
I
Y
--
W
R
D
F
L
P
E
------
I
---
I
P
T
Q
-----------------
E
M
Y
L
N
M
V
M
N
-
K
T
G
------------
G
L
F
R
L
T
L
R
L
M
E
---
A
L
S
P
S
--
H
----------------------------------------------------------------------------------
G
H
S
L
V
P
F
I
----
N
-----
L
L
G
I
I
Y
Q
I
R
D
D
-----
Y
L
N
L
-----
K
D
F
Q
M
S
F
A
E
D
I
T
E
G
K
L
-------------------------------------------------------
S
--
F
P
I
V
H
A
--
L
N
F
T
K
T
K
G
Q
T
E
Q
H
N
E
I
L
R
I
L
L
L
R
---
T
--
S
D
K
D
I
K
L
--
K
L
I
Q
I
L
E
F
-
D
T
N
--------------------
S
L
A
---
Y
T
K
N
F
I
N
Q
L
V
N
M
I
K
-
N
D
-------
N
E
N
K
Y
L
P
E
L
L
Y
I
--
I
D
H
L
S
E
L
----------------
6
PsiBlast_PDB
62.43
27%
-81
- C6 -
3JRO
-
A:
[1291-1425]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
I
E
Q
I
F
------
L
Y
L
L
L
N
D
V
V
R
A
S
K
L
-----------
A
I
--
E
S
K
N
G
H
L
S
V
L
I
S
Y
L
---
G
S
N
D
-----------------
P
R
I
R
D
L
A
E
L
Q
L
Q
K
------------
W
--
S
T
G
G
C
S
I
D
---
K
N
I
S
K
I
Y
K
L
L
S
G
S
P
F
EG---------
L
F
S
L
------------
K
E
L
E
S
E
F
S
W
L
C
L
-
L
N
L
T
L
C
Y
G
---------
Q
---
I
D
E
Y
S
L
E
S
L
V
Q
S
H
L
D
K
F
S
L
P
Y
D
----
D
-----
P
I
G
V
I
F
Q
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
44.35
24%
0
- C5 -
1PN2
-
FOX2_CANTR
A:
[38-122]
-------------------------------------------------
F
Q
V
I
P
T
F
G
H
L
I
T
-
F
N
S
G
K
S
Q
-----
N
S
-
F
A
K
L
L
R
N
F
N
P
M
L
-
L
L
H
G
E
H
Y
L
K
V
H
S
W
P
P
P
T
E
G
E
I
K
T
T
F
----
E
P
I
A
T
T
P
--
K
-------
G
T
N
V
V
I
V
H
G
S
--
K
S
V
D
N
K
S
G
--
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
43.42
24%
-16
- C5 -
1PN4
2
FOX2_CANTR
A:
[38-122]
-------------------------------------------------
F
Q
V
I
P
T
F
G
H
L
I
T
-
F
N
S
G
K
S
Q
-----
N
S
-
F
A
K
L
L
R
N
F
N
P
M
L
-
L
L
H
G
E
H
Y
L
K
V
H
S
W
P
P
P
T
E
G
E
I
K
T
T
F
----
E
P
I
A
T
T
P
--
K
-------
G
T
N
V
V
I
V
H
G
S
--
K
S
V
D
N
K
S
G
--
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
43.23
44%
70
- C6 -
4TKM
2
?
A:
[26-79]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
L
A
R
Y
G
A
V
V
--
G
-
L
N
S
-------
H
V
D
P
A
D
P
A
-----
L
L
L
G
K
L
R
E
A
G
G
D
G
A
F
F
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
43.18
30%
-33
- C6 -
3QQ5
-
?
A:
[339-398]
----------------------------------
P
D
L
E
E
I
E
N
A
K
L
I
I
H
C
G
G
C
I
L
N
R
S
A
M
M
R
R
V
R
M
A
K
R
L
-----
G
I
-
P
--
M
T
N
Y
G
V
T
I
S
-
Y
L
H
G
V
L
E
R
A
I
R
P
F
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
41.68
44%
77
- C6 -
4TKL
1
?
A:
[26-74]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
L
A
R
Y
G
A
V
V
--
G
-
L
N
S
-------
H
V
D
P
A
D
P
A
-----
L
L
L
G
K
L
R
E
A
G
G
D
G
A
F
F
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
41.02
44%
74
- C6 -
4W7I
-
?
A:
[26-74]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
L
A
R
Y
G
A
V
V
--
G
-
L
H
G
-------
R
K
A
P
A
D
P
A
-----
L
L
L
G
K
L
R
E
A
G
G
D
G
A
F
F
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------