@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv1576c: (2016-05-03 )
MTEFDDIKNLSLPETRDAAKQLLDSVAGDLTGEAAQRFQALTRHAEELRAEQRRRGREAEEALRRYRAGELRVVPGAPTGGDDGDAPPGNSLRDTAFRTLDSCVRDGLMSSRAAETAETLCRTGPPQSTSWAQRWLAATGSRDYLGAFVKRVSNPVAGHTVWTDREAAAWREAAAVAAEQRAMGLVDTQGGFLIPAALDPAILLSGDGSTNPIRQVARVVQTTSEIWRGVTSEGAEARWYSEAQEVSDDSPALAQPAVPNYRGSCWIPFSIELEGDAASFVGEIGKILADSVEQLQAAAFVNGSGNGEPTGFVSALTGTSDQVVVGAGSEAIVAADVYALQSALPPRFQASAAFAANLSTINTLRQAETSNGALKFPSLHDSPPMLAGKSVLEVSHMDTVDSAVTATNHPLVLGDWKQFLIGDRVGSMVELVPHLFGPNRRPTGQRGFFAWFRVGSDVLVRNAFRVLKVETTA
Atome Classification :
(20 SA)
.........10........20.....-...30......-..40........50........60........70........80........90........100.....-----..110-.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220--------....--.--.-..-230..--......240.....-.--.250........260.-.-..-...270.....----..280...-....290.......300.-...----.----..--------310.........-320..-.--------....330.......340......-.--350.......360.......---370---....-.-.---..380.-......-.390.......400..-----------------------.-----------------------------------------..----------..410.....--.-.420.......430-..--.....440.......450.......460.......470.
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MTE
F
D
DIKNLSLP
E
T
R
D
A
A
K
Q
L
L
D
S
V
-
A
GDL
T
G
E
A
A
Q
R
-
F
Q
A
L
T
R
H
A
E
E
L
R
A
E
Q
R
RRGR
E
A
E
E
A
L
R
R
YRAGE
L
R
VVPGAPTGGDDGDAPPGN
S
L
R
D
T
A
F
R
T
L
D
S
C
V
R
D
G
-----
L
M
S
S
R
-
A
A
E
T
A
E
T
L
CRTGPPQS
T
S
W
A
Q
R
W
L
A
ATGS
R
D
Y
L
G
A
F
V
K
R
VSNPVAGHTVWTD
R
E
A
A
A
W
R
E
A
A
A
V
A
A
E
Q
RA
M
G
L
V
DTQG
G
F
L
I
PAALD
P
A
I
L
L
SGDGST
N
P
I
R
Q
V
A
R
V
V
Q
---------
T
T
S
E
--
I
--
W
-
R
G-VT-SE--GAEAR
W
Y
S
E
A
Q
EVS-D--DS-PALAQPAVPNYRG-
S
-
C
W
-
I
P
F
S
I
E
LEG
D
A
----
A
S
F
V
G
E
I
G
-
K
I
L
A
D
S
V
E
Q
L
Q
A
A
A
F
VNG-SGN----G----EP--------T--
G
F
V
S
A
LTGT-SD
Q
V
V
-V--------GAGS
E
A
I
V
A
A
D
V
Y
A
L
Q
SALPPRF-Q--A
S
A
AFAA
N
L
S
T
I
N
T
L
R
QAET---S-N---G
A
L
K-F-P---SLHD-S-PPMLAG-K
S
V
L
E
V
SHMDTVD
S
A
V-----------------------T-----------------------------------------AT----------NH
P
L
V
L
G
D
W
K
--
Q
-
F
L
I
G
D
R
V
G
S
M
V
E
L
V
-
P
H
--LFGPNRRPTGQR
G
F
F
A
W
F
RVG
S
D
V
L
V
R
N
A
F
R
V
L
K
V
ETTA
28
Fugue
81.57
11%
-37
- C- -
1OHG
1
CAPSD_BPHK7
A:
[1-281]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
L
G
S
D
A
D
S
A
G
S
L
I
Q
P
M
Q
I
P
G
I
I
M
P
G
L
R
R
L
T
I
R
D
L
L
A
Q
G
R
T
S
---------
S
N
A
L
--
E
--
Y
-
V
R
-
E
E
-
V
F
--
T
N
N
A
D
V
V
A
E
K
A
L
K
P
-
E
--
S
D
-
I
T
F
S
K
Q
T
A
N
V
K
T
I
-
A
-
H
W
-
V
Q
A
S
R
Q
V
M
D
D
A
----
P
M
L
Q
S
Y
I
N
-
N
R
L
M
Y
G
L
A
L
K
E
E
G
Q
L
L
N
G
-
D
G
T
----
G
----
D
N
--------
L
--
E
G
L
N
K
V
A
T
A
-
Y
D
T
S
L
-
N
--------
A
T
G
D
T
--
R
A
D
I
I
A
H
A
I
Y
Q
V
T
E
S
E
-
F
--
S
A
S
G
I
V
L
N
P
R
D
W
H
N
I
A
L
L
K
D
---
N
-
E
---
G
R
Y
I
-
F
G
G
---
P
Q
A
F
-
T
-
S
N
I
M
W
G
-
L
P
V
V
P
T
K
A
Q
A
-----------------------------------------------------------------------------------
A
G
T
F
T
V
G
G
F
D
--
M
A
S
Q
V
W
D
R
M
D
A
T
V
E
V
S
-
R
E
----
D
R
D
N
F
V
K
N
M
L
T
I
L
C
E
E
R
L
A
L
A
H
Y
R
P
T
A
I
I
K
G
T
F
S
S
G
-
11
HHSearch
81.19
13%
-58
- C- -
1OHG
1
CAPSD_BPHK7
A:
[6-281]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
D
S
A
G
S
L
I
Q
P
M
Q
I
P
G
I
I
M
-
P
G
L
R
R
L
T
-
I
R
D
L
L
A
Q
G
R
---------
T
S
S
N
--
A
L
E
Y
-
V
R
-
E
E
-
V
F
--
T
N
N
A
D
V
V
A
E
K
A
L
K
P
-
E
--
S
D
-
I
T
F
S
K
Q
T
A
N
V
K
T
I
-
A
-
H
W
-
V
Q
A
S
R
Q
V
M
D
D
A
----
P
M
L
Q
S
Y
I
N
-
N
R
L
M
Y
G
L
A
L
K
E
E
G
Q
L
L
N
G
-
D
G
T
----
G
D---
N
L
--------
E
--
G
L
N
K
V
A
T
A
Y
-
D
---
T
-
S
--------
L
N
A
T
G
D
T
R
A
D
I
I
A
H
A
I
Y
Q
V
T
E
S
E
-
F
--
S
A
S
G
I
V
L
N
P
R
D
W
H
N
I
A
L
L
K
D
---
N
-
E
---
G
R
Y
I
-
F
G
G
---
P
Q
-
A
-
F
T
S
N
I
M
W
G
-
L
P
V
V
P
T
K
A
Q
A
A
-----------------------------------------------------------------------
G
------------
T
F
T
V
G
G
F
D
M-
A
-
S
Q
V
W
D
R
M
D
A
T
V
E
V
S
-
R
E
DR
D
N
F
----
V
K
N
M
L
T
I
L
C
E
E
R
L
A
L
A
H
Y
R
P
T
A
I
I
K
G
T
F
S
S
G
-
10
HHSearch
76.27
13%
-65
- C2 -
3QPR
-
CAPSD_BPHK7
A:
[119-383]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
Q
I
P
G
I
I
M
-
P
G
L
R
R
L
T
-
I
R
D
L
L
A
Q
G
R
---------
T
S
S
N
--
A
L
E
Y
-
V
R
-
E
E
-
V
F
--
T
N
N
A
---------
P
-
E
--
S
D
-
I
T
F
S
K
Q
T
A
N
V
K
T
I
-
A
-
H
W
-
V
Q
A
S
R
Q
V
M
D
D
A
----
P
M
L
Q
S
Y
I
N
-
N
R
L
M
Y
G
L
A
L
K
E
E
G
Q
L
L
N
G
-
D
G
T
----
G
D---
N
L
--------
E
--
G
L
N
K
V
A
T
A
Y
-
D
---
T
-
S
--------
L
N
A
T
G
D
T
R
A
D
I
I
A
H
A
I
Y
Q
V
T
E
S
E
-
F
--
S
A
S
G
I
V
L
N
P
R
D
W
H
N
I
A
L
L
K
D
---
N
-
E
---
G
R
Y
I
-
F
-
G
---
G
P
Q
A
-
F
T
S
N
I
M
W
G
-
L
P
V
V
P
T
K
A
Q
A
A
-----------------------------------------------------------------------
G
------------
T
F
T
V
G
G
F
D
M-
A
-
S
Q
V
W
D
R
M
D
A
T
V
E
V
S
-
R
E
--
D
R
--
D
N
F
V
K
N
M
L
T
I
L
C
E
E
R
L
A
L
A
H
Y
R
P
T
A
I
I
K
G
T
F
S
S
--
13
HHSearch
72.27
10%
-52
- C2 -
3J7W
-
CAPSA_BPT7
A:
[21-344]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
G
D
K
L
A
L
F
L
K
V
F
G
G
E
V
L
-
T
A
F
A
R
T
S
V
T
T
S
R
H
M
V
R
S
---------
I
S
S
G
K-
S
A
Q
F
-
P
V
-
L
G
-
R
---
T
Q
-
A
A
Y
L
A
P
G
E
N
L
D
D
K
--
R
K
D
I
K
H
T
E
K
V
I
T
I
D
G
L
-
L
T
A
D
-
V
L
I
Y
D
I
E
D
A
M
N
H---
Y
D
V
R
S
E
Y
T
-
S
Q
L
G
E
S
L
A
M
A
A
D
G
A
V
L
A
E
-
I
A
G
----
L
CNVE
S
K
--------
Y
NE
N
I
-
E
G
L
G
T
A
-
T
V
I
E
T
-
T
QNKAALTD
Q
V
A
L
G
K
E
I
I
A
A
L
T
K
A
R
A
A
L
T
K
N
Y
-
V
PA
A
D
R
V
F
Y
C
D
P
D
S
Y
S
A
I
L
A
A
L
M
---
P
N
A
---
A
N
Y
A
-
A
L
I
---
D
P
E
K
-
G
S
I
R
N
V
M
G
-
F
E
V
V
E
V
P
H
L
T
A
G
G
A
G
T
AREGTTGQKHVFPANKGEGNVKV
A
-----------------------------------------
K
D
----------
N
V
I
G
L
F
M
H
R
S
--
A
-
V
G
T
V
K
L
R
D
L
A
L
E
R
A
-
R
R
----
A
----
N
F
Q
A
D
Q
I
I
A
K
Y
A
M
G
H
G
G
L
R
P
E
A
A
G
A
V
V
F
K
V
--
16
HHSearch
60.61
8%
-54
- C2 -
3DKT
1
MARIT_THEMA
A:
[67-264]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
G
L
R
K
S
L
P
L
I
E
L
-
R
-
A
T
-
F
T
L
D
L
W
E
L
D
N
L
E
R
GK
P
N
V
D
L
S
S
L
-
E
E
T
V
R
K
V
A
E
F
E
D
E
V
I
F
R
G
-
C
E
K
----
S
----
G
V
--------
K
--
G
L
L
S
F
E
E
R
K
-----
I
-
E
--------
C
G
S
T
P
K
D
L
L
E
A
I
V
R
A
L
S
I
F
S
K
D
G
-
I
E-
G
P
Y
T
L
V
I
N
T
D
R
W
I
N
F
L
K
E
E
A
---------
G
H
Y
P
-
L
-
E
---
K
R
-----
V
E
E
C
L
R
G
G
K
I
I
T
T
P
R
I
E
------------------------------------------------------------------------
D
-------------
A
L
V
V
S
E
R
GG
D
-
F
K
L
I
L
G
Q
D
L
S
I
G
Y
E
-
D
R
---------
E
K
D
A
V
R
L
F
I
T
E
T
F
T
F
Q
V
V
N
P
E
A
L
I
L
L
K
-----
12
HHSearch
59.12
10%
-53
- C2 -
4PT2
-
?
P:
[20-278]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
N
E
T
V
I
-
Q
V
A
R
R
S
L
V
G
R
R
I
L
D
I
Y
G
P--------
L
G
A
G
VQ
T
--
V
-
P
Y
-
D
E
F
Q
G
VS
P
G
A
V
D
I
V
G
E
-
Q
E
T
A
-
M
--
V
F
-
T
D
A
-
R
K
F
K
T
I
P
I
I
-
Y
-
K
D
-
F
L
L
H
W
R
D
I
E
A
A
RTHN
M
P
L
D
V
S
A
A
-
A
G
A
A
A
L
C
A
Q
Q
E
D
E
L
I
F
Y
G
-
D
A
R
----
L
----
G
Y
--------
E
--
G
L
M
T
A
N
G
R
L
-
T
V
P
-
L
-
G
--------
D
W
T
S
P
G
G
G
F
Q
A
I
V
E
A
T
R
K
L
N
E
Q
G
H
F
--
G
P
Y
A
V
V
L
S
P
R
L
Y
S
Q
L
H
R
I
Y
E
---
K
-
T
---
G
V
L
E
-
I
-
E
---
T
------
I
R
Q
L
A
S
-
D
G
V
Y
Q
S
N
R
L
R
G
-----------------------------------------------------------------------------------
E
S
G
V
V
V
S
T
G
RE
N
-
M
D
L
A
V
S
M
D
M
V
A
A
Y
L
-
G
A
---------
S
R
M
N
H
P
F
R
V
L
E
A
L
L
L
R
I
K
H
P
D
A
I
C
T
L
------
32
Fugue
58.70
22%
40
- C2 -
3FN2
1
?
A:
[6-102]
------------------------
Y
T
M
Q
R
D
N
Q
K
T
L
A
V
Y
M
F
E
E
I
N
R
D
V
E
Y
L
S
G
--
R
L
S
E
K
E
L
K
D
K
Y
R
Y
Y
G
R
G
Y
V
R
I
T
D
---
K
D
G
Q
V
I
T
Y
E
D
G
S
V
Q
D
K
T
V
F
L
T
N
E
G
A
N
K
L
G
W
K
L
E
F
L
I
D
E
K
M
F
E
E
E
I
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
HHSearch
57.37
11%
5
- C- -
2XD8
-
?
A:
[25-363]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
K
Y
A
L
Y
L
K
L
F
S
G
E
M
F
-
K
G
F
Q
H
E
T
I
A
R
D
L
V
T
K
R
T
---------
L
K
N
G
K-
S
L
Q
F
-
I
Y
-
T
G
-
R
----
M
T
S
S
F
H
T
P
G
T
P
I
L
G
N
A
D
K
A
-
P
P
V
A
E
K
T
I
V
M
D
D
L
-
L
-
I
S
S
A
F
V
Y
D
L
D
E
T
L
A
H
---
Y
E
L
R
G
E
I
S
-
K
K
I
G
Y
A
L
A
E
K
Y
D
R
L
I
F
R
S
-
I
T
R
----
G
----
A
R
S
A
SPVSAT
N
--
F
V
E
P
G
G
T
Q
I
-
R
V
G
S
G
T
N
ES------
D
A
F
T
A
S
A
L
V
N
A
F
Y
D
A
A
A
A
M
D
E
K
G
-
V
SS
Q
G
R
C
A
V
L
N
P
R
Q
Y
Y
A
L
I
Q
D
I
G
---
S
-
N
GLV
N
R
D
V
-
Q
-
G
SAL
Q
S
G
N
-
G
V
I
E
-
I
A
G
-
I
H
I
Y
K
S
M
N
I
P
F
L
G
K
Y
G
-----------------------
V
KYGGTTG
E
T
S
P
G
N
L
G
SHIGPTPENANATGGVNNDYGTNA
E
L
G
A
----------
K
S
C
G
L
I
F
Q
K
E
--
A
-
A
G
V
V
E
A
I
G
P
Q
V
Q
V
T
-
N
G
--
D
V
S
V
---
I
Y
Q
G
D
V
I
L
G
R
M
A
M
G
A
D
Y
L
N
P
A
A
A
V
--------
18
HHSearch
52.89
9%
-61
- C2 -
2E0Z
-
?
A:
[160-345]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
E
Y
K
P
I
P
L
L
-
K
-
K
K
-
F
Y
V
G
I
R
E
L
N
D
G
-----
T
Y
D
V
S
I
A
-
T
K
A
G
E
L
L
V
K
D
E
E
S
L
V
I
R
E
I
L
S
T
----
E
----
G
I
--------
K
--
K
M
K
L
S
S
--
W
------------------
D
N
P
E
E
A
L
N
D
L
M
N
A
L
Q
E
A
S
N
A
S
-
A
--
G
P
F
G
L
I
I
N
P
K
R
Y
A
K
L
L
K
I
Y
E
---
K
-
S
---
G
K
M
L
-
V
-
E
---
V
L
------
K
E
I
F
R
-
G
G
I
I
V
T
L
N
I
D
E
-----------------------------------------------------------------------
N
------------
K
V
I
I
F
A
N
T
PA
V
-
L
D
V
V
V
G
Q
D
V
T
L
Q
E
L
-
G
P
---------
E
G
D
D
V
A
F
L
V
S
E
A
I
G
I
R
I
K
N
P
E
A
I
V
V
L
E
-----
6
PsiBlast_PDB
50.01
25%
28
- C2 -
4CLQ
-
RCL1_YEAST
A:
[210-307]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
G
A
K
K
V
L
K
N
L
Q
C
E
V
N
---------
I
T
A
D
--
V
--
W
-
R
G
-------------------
E
N
S
-
G
--
K
S
-
P
G
W
G
I
T
L
V
A
Q
S
K
Q
-
K
-
G
W
-
S
Y
F
A
E
D
I
-
G
D
A
----
G
S
I
P
E
E
L
G
E
K
V
A
C
Q
L
L
E
E
I
S
K
S
A
A
V
---
G
R
N
----
Q
----
L
P
--------
L
--
A
I
V
Y
M
V
I
G
K
-
E
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_CBE
49.69
38%
93
- C2 -
4M9Q
1
ARL13_CHLRE
B:
[159-198]
---------------
R
D
G
L
K
W
L
V
G
T
V
-
D
R
E
F
-
G
R
L
D
P
R
-
V
Q
T
---
E
A
E
E
V
R
Q
E
E
A
R
K
K
K
E
R
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
48.15
38%
78
- C2 -
5DI3
-
ARL13_CHLRE
B:
[159-205]
---------------
R
D
G
L
K
W
L
V
G
T
V
-
D
R
E
F
-
G
R
L
D
P
R
-
V
Q
T
---
E
A
E
E
V
R
Q
E
E
A
R
K
K
K
E
R
E
E
R
L
R
K
Q
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
Fugue
46.16
15%
66
- C2 -
5AJS
-
?
A:
[252-314]
-------
T
T
E
E
E
L
L
R
K
L
N
E
Q
R
D
I
L
A
L
-
M
E
V
K
M
K
E
M
K
G
S
-
I
R
H
L
R
L
T
E
A
K
L
R
E
E
L
R
E
K
D
R
L
L
A
M
A
V
I
R
K
K
H
G
M
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
Fugue
46.10
12%
75
- C2 -
1URQ
-
STXB5_RAT
A:
[1052-1108]
---------
I
E
G
V
K
G
A
A
S
G
V
V
G
E
L
A
R
-
A
R
L
A
L
D
E
R
G
Q
K
-
L
S
D
L
E
E
R
T
A
A
M
M
S
S
A
D
S
F
S
K
H
A
H
E
M
M
L
K
Y
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
45.76
7%
-2
- C- -
4BML
-
?
A:
[24-331]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
R
Y
A
T
A
L
K
L
F
S
G
E
V
F
-
T
A
F
N
N
A
S
I
F
K
G
L
V
R
S
Y
D
---------
L
R
G
G
K-
S
KQ
F
-
M
F
-
T
G
-
K
----
L
S
A
G
Y
H
T
P
G
T
P
I
V
-
G
D
-
A
G
-
I
K
A
N
E
K
T
L
V
M
D
D
L
L
V
-
S
S
-
Q
F
V
Y
S
L
D
E
I
F
S
Q
---
Y
S
T
R
A
E
V
S
-
K
Q
I
G
E
A
L
A
T
H
Y
D
E
R
I
A
R
V
-
L
A
K
A
SAE
A
S---
P
V
--------
T
--
G
E
P
G
G
F
H
V
N
-
I
--
G
A
-
G
--------
N
T
N
D
A
Q
A
I
V
D
G
F
F
E
A
A
A
V
L
D
E
R
S
-
A
PQ
E
G
R
V
A
V
L
S
P
R
Q
Y
Y
S
L
I
S
S
V
D
TNI
L
-
N
---
R
E
I
G
N
S
-
Q
G--
D
M
N
S
G
K
G
L
Y
S
I
A
G
-
I
R
I
L
K
S
N
N
L
A
G
L
Y
G
Q
D
-----------------------
L
SSAAV------------------------------------
T
G
ENNDYQVDAS
A
L
A
G
L
I
F
H
R
E
--
A
-
A
G
C
I
Q
S
V
A
P
T
I
Q
T
T
S
G
D
--
F
N
V
----
Q
Y
Q
G
D
L
I
V
G
K
L
A
M
G
C
G
S
L
R
T
S
V
A
G
S
F
Q
A
----
20
HHSearch
45.62
16%
13
- C2 -
3J4U
-
?
A:
[24-150]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
D
P
Q
I
V
-
E
M
L
N
E
T
N
E
I
L
D
D
M
T
V
I
E
---------
A
N
G
F
--
T
--
E
H
K
T
T
V
R
-
S
G
--
L
P
T
G
T
W
R
K
L
N
Y
G
V
Q
-
P
--
E
K
-
S
R
T
V
Q
V
K
D
S
M
G
M
L
-
E
-
T
Y
-
A
E
V
D
K
A
L
A
D
L
N
GN
S
-
A
A
W
R
L
S
E
D
-
R
A
F
I
E
G
M
N
Q
T
Q
A
T
T
L
F
Y
G
-
D
S
S
----
I
DAE-
K
F
--------
M
--
G
L
T
P
R
F
N
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
45.34
38%
94
- C2 -
4M9Q
1
ARL13_CHLRE
A:
[159-196]
---------------
R
D
G
L
K
W
L
V
G
T
V
-
D
R
E
F
-
G
R
L
D
P
R
-
V
Q
T
---
E
A
E
E
V
R
Q
E
E
A
R
K
K
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
HHSearch
44.25
9%
-33
- C- -
4AN5
-
?
A:
[38-225]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
D
ELNAL
A
K
K
A
G
G
G
S
T
L
N
--
M
-
P
Y
-
W
N
--------------------------
I
N
A
G
Q
D
K
A
V
L
I
L
R
-
G
-
N
A
-
W
S
S
H
D
L
A
A
T
L
S
G---
S
D
P
M
Q
A
I
G
-
S
R
V
A
A
Y
W
A
R
E
M
Q
K
I
V
F
A
E
-
L
---------------------
A
--
G
V
F
S
N
D
D
M
K
D
N
K
L
D
I
-
S
--------
G
T
A
D
G
I
Y
S
A
E
T
F
V
D
A
S
Y
K
L
G
D
H
E
-
S
--
L
L
T
A
I
G
M
H
S
A
T
M
A
S
A
V
K
Q
D
L
---------
I
E
F
V
-
K
-
D
---
S
Q
S
G
-
I
R
F
P
T
Y
M
N
-
K
R
V
I
V
D
D
S
M
P
V
E
---------------------------------------------------------------------------------------------------------------------------------------------------------
29
Fugue
44.02
22%
155
- C2 -
4PAS
-
A:
[767-801]
-------------------------------
E
E
E
K
S
R
L
-
L
E
K
E
N
R
E
L
E
K
I
I
A
E
K
E
E
R
V
S
E
L
R
H
Q
L
Q
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
Fugue
43.84
15%
113
* C2 *
4PAS
-
GABR2_HUMAN
B:
[779-817]
-----------------------------
S
V
N
Q
A
S
T
S
R
-
L
E
G
L
Q
S
E
N
H
H
L
R
M
K
I
T
E
L
D
K
D
L
E
E
V
T
M
Q
L
Q
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------