@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA2222: (2016-02-05 )
MAEINIYQNPGQSLANIYKGFARQCNPGFVFPEAQTIEAWDIPLRLHPEFIPGGDISKADQQYSTLLAQEIANGVTIGFRMVNEKERVCNVEILPLLTSMAQNLDRIKARFGSGYLDRFKGSPNVYPTDVGFSTDASGGISQESGLLVSYGVNLRTLTPGTWQAMTLPEDIKALVGPGVGLRLDAPNFSDVFNTIKSGLRYTTAVTLLLAYFAAI
Atome Classification :
(20 SA)
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10........20........30........40........50........60.---.......70........80.........90--.....----...100.---......110.......120-.........130.......140------------.......150.----.---.--....160....--...170...--.--...-180.......190.......-------200.......210...------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M
A
E
I
N
I
YQNP
G
Q
S
L
A
N
I
Y
K
G
F
A
RQCNPGFVFPEAQ
T
I
E
A
W
D
I
P
L
R
LHPEFIPGGDI
S
K
A
D
Q
Q
---
Y
S
T
L
L
A
Q
E
I
AN
G
V
T
I
G
F
R
-
M
VNE
K
E
RVCN
V
--
E
I
L
P
L
----
L
T
S
M
A
Q
N
---
L
D
R
I
K
A
R
FGSG
Y
L
D
RFK---GSPNVYPTDVGFSTDASGGISQ------------ES
G
L
L
V
S
YGV
N
----
L
---
R
--
T
LTPGT
W
Q
AMT--
L
P
E
D
I
K
A
L
V--G--PGV-
G
L
R
LDAP
N
F
S
D
V
F
N
T
I
K
SGL-------
R
Y
T
T
A
V
T
L
L
L
A
Y
F
AAI------------------------------------------------------------------
20
PsiBlast_CBE
98.71
98%
-124
- C5 -
2IGS
3
?
H:
[6-217]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
N
I
Y
Q
N
P
G
Q
S
L
A
N
I
Y
K
G
F
A
R
Q
C
N
P
G
F
V
F
P
E
A
Q
T
I
E
A
W
D
I
P
L
R
L
H
P
E
F
I
P
G
G
D
I
S
K
A
D
Q
Q
---
Y
S
T
L
L
A
Q
E
I
A
N
G
V
T
I
G
F
R
-
M
V
N
E
K
E
R
V
C
N
V
--
E
I
L
P
L
----
L
T
S
M
A
Q
N
---
L
D
R
I
K
A
R
F
G
S
G
Y
L
D
R
F
K
---
G
S
P
N
V
Y
P
T
D
V
G
F
S
T
D
A
S
G
G
I
S
Q
------------
E
S
G
L
L
V
S
Y
G
V
N
----
L
---
R
--
T
L
T
P
G
T
W
Q
A
M
T
--
L
P
E
D
I
K
A
L
V
--
G
--
P
G
V
-
G
L
R
L
D
A
P
N
F
S
D
V
F
N
T
I
K
S
G
L
-------
R
Y
T
T
A
V
T
L
L
L
A
Y
F
A
A
I
------------------------------------------------------------------
22
PsiBlast_CBE
98.15
98%
-123
- C5 -
2IGS
3
?
F:
[4-217]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
E
I
N
I
Y
Q
N
P
G
Q
S
L
A
N
I
Y
K
G
F
A
R
Q
C
N
P
G
F
V
F
P
E
A
Q
T
I
E
A
W
D
I
P
L
R
L
H
P
E
F
I
P
G
G
D
I
S
K
A
D
Q
Q
---
Y
S
T
L
L
A
Q
E
I
A
N
G
V
T
I
G
F
R
-
M
V
N
E
K
E
R
V
C
N
V
--
E
I
L
P
L
----
L
T
S
M
A
Q
N
---
L
D
R
I
K
A
R
F
G
S
G
Y
L
D
R
F
K
---
G
S
P
N
V
Y
P
T
D
V
G
F
S
T
D
A
S
G
G
I
S
Q
------------
E
S
G
L
L
V
S
Y
G
V
N
----
L
---
R
--
T
L
T
P
G
T
W
Q
A
M
T
--
L
P
E
D
I
K
A
L
V
--
G
--
P
G
V
-
G
L
R
L
D
A
P
N
F
S
D
V
F
N
T
I
K
S
G
L
-------
R
Y
T
T
A
V
T
L
L
L
A
Y
F
A
A
I
------------------------------------------------------------------
26
HHSearch
98.04
100%
-122
- C5 -
2IGS
4
?
A:
[6-217]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
N
I
Y
Q
N
P
G
Q
S
L
A
N
I
Y
K
G
F
A
R
Q
C
N
P
G
F
V
F
P
E
A
Q
T
I
E
A
W
D
I
P
L
R
L
H
P
E
F
I
P
G
G
D
I
S
K
A
D
Q
Q
---
Y
S
T
L
L
A
Q
E
I
A
N
G
V
T
I
G
F
R
-
M
V
N
E
K
E
R
V
C
N
V
--
E
I
L
P
L
----
L
T
S
M
A
Q
N
---
L
D
R
I
K
A
R
F
G
S
G
Y
L
D
R
F
K
---
G
S
P
N
V
Y
P
T
D
V
G
F
S
T
D
A
S
G
G
I
S
Q
------------
E
S
G
L
L
V
S
Y
G
V
N
----
L
---
R
--
T
L
T
P
G
T
W
Q
A
M
T
--
L
P
E
D
I
K
A
L
V
--
G
--
P
G
V
-
G
L
R
L
D
A
P
N
F
S
D
V
F
N
T
I
K
S
G
L
-------
R
Y
T
T
A
V
T
L
L
L
A
Y
F
A
A
I
------------------------------------------------------------------
23
PsiBlast_CBE
97.81
98%
-121
- C5 -
2IGS
7
?
D:
[6-217]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
N
I
Y
Q
N
P
G
Q
S
L
A
N
I
Y
K
G
F
A
R
Q
C
N
P
G
F
V
F
P
E
A
Q
T
I
E
A
W
D
I
P
L
R
L
H
P
E
F
I
P
G
G
D
I
S
K
A
D
Q
Q
---
Y
S
T
L
L
A
Q
E
I
A
N
G
V
T
I
G
F
R
-
M
V
N
E
K
E
R
V
C
N
V
--
E
I
L
P
L
----
L
T
S
M
A
Q
N
---
L
D
R
I
K
A
R
F
G
S
G
Y
L
D
R
F
K
---
G
S
P
N
V
Y
P
T
D
V
G
F
S
T
D
A
S
G
G
I
S
Q
------------
E
S
G
L
L
V
S
Y
G
V
N
----
L
---
R
--
T
L
T
P
G
T
W
Q
A
M
T
--
L
P
E
D
I
K
A
L
V
--
G
--
P
G
V
-
G
L
R
L
D
A
P
N
F
S
D
V
F
N
T
I
K
S
G
L
-------
R
Y
T
T
A
V
T
L
L
L
A
Y
F
A
A
I
------------------------------------------------------------------
21
PsiBlast_CBE
97.70
98%
-123
- C5 -
2IGS
2
?
G:
[6-217]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
N
I
Y
Q
N
P
G
Q
S
L
A
N
I
Y
K
G
F
A
R
Q
C
N
P
G
F
V
F
P
E
A
Q
T
I
E
A
W
D
I
P
L
R
L
H
P
E
F
I
P
G
G
D
I
S
K
A
D
Q
Q
---
Y
S
T
L
L
A
Q
E
I
A
N
G
V
T
I
G
F
R
-
M
V
N
E
K
E
R
V
C
N
V
--
E
I
L
P
L
----
L
T
S
M
A
Q
N
---
L
D
R
I
K
A
R
F
G
S
G
Y
L
D
R
F
K
---
G
S
P
N
V
Y
P
T
D
V
G
F
S
T
D
A
S
G
G
I
S
Q
------------
E
S
G
L
L
V
S
Y
G
V
N
----
L
---
R
--
T
L
T
P
G
T
W
Q
A
M
T
--
L
P
E
D
I
K
A
L
V
--
G
--
P
G
V
-
G
L
R
L
D
A
P
N
F
S
D
V
F
N
T
I
K
S
G
L
-------
R
Y
T
T
A
V
T
L
L
L
A
Y
F
A
A
I
------------------------------------------------------------------
36
Fugue
97.67
99%
-120
- C5 -
2IGS
4
?
A:
[6-219]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
N
I
Y
Q
N
P
G
Q
S
L
A
N
I
Y
K
G
F
A
R
Q
C
N
P
G
F
V
F
P
E
A
Q
T
I
E
A
W
D
I
P
L
R
L
H
P
E
F
I
P
G
G
D
I
S
K
A
D
Q
Q
---
Y
S
T
L
L
A
Q
E
I
A
N
G
V
T
I
G
F
R
M
V
-
N
E
K
E
R
V
C
N
V
--
E
I
L
P
L
----
L
T
S
M
A
Q
N
---
L
D
R
I
K
A
R
F
G
S
G
Y
L
D
R
F
K
---
G
S
P
N
V
Y
P
T
D
V
G
F
S
T
D
A
S
G
G
I
S
Q
------------
E
S
G
L
L
V
S
Y
G
V
N
----
L
---
R
--
T
L
T
P
G
T
W
Q
A
M
T
--
L
P
E
D
I
K
A
L
V
--
G
--
P
G
V
-
G
L
R
L
D
A
P
N
F
S
D
V
F
N
T
I
K
S
G
L
-------
R
Y
T
T
A
V
T
L
L
L
A
Y
F
A
A
I
GS----------------------------------------------------------------
1
PsiBlast_PDB
97.64
98%
-122
- C5 -
2IGS
4
?
A:
[6-217]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
N
I
Y
Q
N
P
G
Q
S
L
A
N
I
Y
K
G
F
A
R
Q
C
N
P
G
F
V
F
P
E
A
Q
T
I
E
A
W
D
I
P
L
R
L
H
P
E
F
I
P
G
G
D
I
S
K
A
D
Q
Q
---
Y
S
T
L
L
A
Q
E
I
A
N
G
V
T
I
G
F
R
-
M
V
N
E
K
E
R
V
C
N
V
--
E
I
L
P
L
----
L
T
S
M
A
Q
N
---
L
D
R
I
K
A
R
F
G
S
G
Y
L
D
R
F
K
---
G
S
P
N
V
Y
P
T
D
V
G
F
S
T
D
A
S
G
G
I
S
Q
------------
E
S
G
L
L
V
S
Y
G
V
N
----
L
---
R
--
T
L
T
P
G
T
W
Q
A
M
T
--
L
P
E
D
I
K
A
L
V
--
G
--
P
G
V
-
G
L
R
L
D
A
P
N
F
S
D
V
F
N
T
I
K
S
G
L
-------
R
Y
T
T
A
V
T
L
L
L
A
Y
F
A
A
I
------------------------------------------------------------------
25
PsiBlast_CBE
97.28
98%
-122
- C5 -
2IGS
4
?
B:
[4-217]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
E
I
N
I
Y
Q
N
P
G
Q
S
L
A
N
I
Y
K
G
F
A
R
Q
C
N
P
G
F
V
F
P
E
A
Q
T
I
E
A
W
D
I
P
L
R
L
H
P
E
F
I
P
G
G
D
I
S
K
A
D
Q
Q
---
Y
S
T
L
L
A
Q
E
I
A
N
G
V
T
I
G
F
R
-
M
V
N
E
K
E
R
V
C
N
V
--
E
I
L
P
L
----
L
T
S
M
A
Q
N
---
L
D
R
I
K
A
R
F
G
S
G
Y
L
D
R
F
K
---
G
S
P
N
V
Y
P
T
D
V
G
F
S
T
D
A
S
G
G
I
S
Q
------------
E
S
G
L
L
V
S
Y
G
V
N
----
L
---
R
--
T
L
T
P
G
T
W
Q
A
M
T
--
L
P
E
D
I
K
A
L
V
--
G
--
P
G
V
-
G
L
R
L
D
A
P
N
F
S
D
V
F
N
T
I
K
S
G
L
-------
R
Y
T
T
A
V
T
L
L
L
A
Y
F
A
A
I
------------------------------------------------------------------
24
PsiBlast_CBE
97.14
98%
-123
- C5 -
2IGS
3
?
C:
[6-217]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
N
I
Y
Q
N
P
G
Q
S
L
A
N
I
Y
K
G
F
A
R
Q
C
N
P
G
F
V
F
P
E
A
Q
T
I
E
A
W
D
I
P
L
R
L
H
P
E
F
I
P
G
G
D
I
S
K
A
D
Q
Q
---
Y
S
T
L
L
A
Q
E
I
A
N
G
V
T
I
G
F
R
-
M
V
N
E
K
E
R
V
C
N
V
--
E
I
L
P
L
----
L
T
S
M
A
Q
N
---
L
D
R
I
K
A
R
F
G
S
G
Y
L
D
R
F
K
---
G
S
P
N
V
Y
P
T
D
V
G
F
S
T
D
A
S
G
G
I
S
Q
------------
E
S
G
L
L
V
S
Y
G
V
N
----
L
---
R
--
T
L
T
P
G
T
W
Q
A
M
T
--
L
P
E
D
I
K
A
L
V
--
G
--
P
G
V
-
G
L
R
L
D
A
P
N
F
S
D
V
F
N
T
I
K
S
G
L
-------
R
Y
T
T
A
V
T
L
L
L
A
Y
F
A
A
I
------------------------------------------------------------------
41
Fugue
35.75
12%
-60
- C3 -
4U6U
-
?
B:
[8-289]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Q
D
I
L
E
P
F
E
R
A
L
K
L
Q
T
V
S
S
K
I
H
Q
T
T
T
L
L
R
S
S
L
I
Y
V
H
M
I
S
Q
L
Q
M
M
P
L
E
T
D
S
T
D
D
A
A
L
A
C
G
L
K
I
A
A
L
H
S
Q
L
K
I
N
I
A
A
N
P
N
L
A
T
L
Q
L
I
K
S
C
E
N
N
V
V
S
P
N
R
Q
E
---
L
L
R
Y
L
S
T
N
L
T
R
D
C
L
N
N
L
K
-
M
E
N
N
P
K
R
I
V
T
L
I
K
A
L
Y
T
L
S
P
V
D
L
F
D
T
I
D
K
---
V
L
S
S
K
I
Q
T
T
A
Q
V
L
S
K
T
I
---
T
S
I
R
N
F
N
L
S
L
D
D
A
M
E
N
R
N
S
I
L
T
L
Q
N
L
M
A
A
CAIEG
N
T
N
T
L
R
N
Y
L
S
Q
----
R
---
K
FS
S
L
I
D
Q
F
W
S
K
V
T
N
S
F
K
R
D
F
E
M
S
Y
N
R
G
--
G
P
V
-
G
K
S
L
Q
S
-
N
S
N
L
I
Y
E
A
I
S
K
C
F
GENDPSN
E
L
Q
G
E
L
Q
Y
I
L
K
A
V
S
I
L
D-----------------------------------------------------------------
9
PsiBlast_PDB
34.86
28%
-60
- C5 -
3VC6
3
?
A:
[171-263]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
W
A
---
G
H
P
G
K
P
E
D
R
F
G
P
A
L
D
P
D
G
I
V
A
Q
------------
A
R
L
L
I
G
E
Y
G
F
R
----
S
---
I
--
K
L
K
G
G
V
F
P
P
E
Q
--
E
A
E
A
I
Q
A
L
R
--
D
A
F
P
G
L
-
P
L
R
L
D
-
P
N
A
A
---
W
T
V
E
T
S
I
-------
R
V
G
R
A
L
D
G
V
L
E
Y
L
E
D
P
------------------------------------------------------------------
10
PsiBlast_PDB
34.78
28%
-60
- C5 -
4DHG
1
?
A:
[171-263]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
W
A
---
G
H
P
G
K
P
E
D
R
F
G
P
A
L
D
P
D
G
I
V
A
Q
------------
A
R
L
L
I
G
E
Y
G
F
R
----
S
---
I
--
K
L
K
G
G
V
F
P
P
E
Q
--
E
A
E
A
I
Q
A
L
R
--
D
A
F
P
G
L
-
P
L
R
L
D
-
P
N
A
A
---
W
T
V
E
T
S
I
-------
R
V
G
R
A
L
D
G
V
L
E
Y
L
E
D
P
------------------------------------------------------------------
8
PsiBlast_PDB
34.62
28%
-57
- C5 -
3VC5
1
?
A:
[171-263]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
W
A
---
G
H
P
G
K
P
E
D
R
F
G
P
A
L
D
P
D
G
I
V
A
Q
------------
A
R
L
L
I
G
E
Y
G
F
R
----
S
---
I
--
K
L
K
G
G
V
F
P
P
E
Q
--
E
A
E
A
I
Q
A
L
R
--
D
A
F
P
G
L
-
P
L
R
L
D
-
P
N
A
A
---
W
T
V
E
T
S
I
-------
R
V
G
R
A
L
D
G
V
L
E
Y
L
E
D
P
------------------------------------------------------------------
37
Fugue
32.95
14%
-44
- C5 -
4XDN
5
SCC4_YEAST
A:
[24-640]
G
D
K
L
S
I
S
Q
V
Y
H
L
A
Q
E
Y
R
D
H
A
Y
S
I
A
NKIGS
E
E
G
L
K
Q
Y
Y
G
L
M
N
M
S
I
Q
M
F
Q
L
L
K
T
KCTLS
V
L
E
D
S
K
V
T
F
E
M
V
E
L
L
I
Q
ETYN
F
D
L
A
E
L
Y
I
S
S
L
K
E
R
L
Q
T
H
QSDTDL
V
E
E
I
M
R
C
E
F
L
L
L
H
D
L
P
L
M
R
DS
K
F
H
Y
K
I
A
L
R
N
C
N
E
L
V
Q
Y
M
V
N
LQD
E
L
Y
Q
N
W
A
S
V
F
Q
Y
V
G
V
M
L
C
I
K
L
KQ
H
R
R
V
K
T
S
F
H
G
L
L
S
Q
CREKS
Q
W
K
W
F
L
N
L
C
Y
V
N
Y
L
L
N
E
RFPIP
E
D
A
L
Q
E
L
R
S
TELHTVG
P
E
L
Y
A
W
K
L
A
L
E
M
V
I
Q
L
C
K
DGNI
T
D
H
L
N
E
F
K
N
F
F
D
T
N
K
Q
S
L
V
T
N
EGKGCVIKIMPR
I
A
L
K
V
E
L
PMIFH
Y
K
E
L
K
N
I
L
L
L
L
Q
S
V
S
Y
I
VNCYD
E
K
G
N
F
S
R
K
F
L
P
K
V
Y
S
T
T
Q
K
L
I
K
N
I
A
A
G
G
V
S
M
N
E
L
D
S
R
I
Q
T
Y
K
S
I
L
E
F
C
E
--
F
Y
K
V
W
E
Q
T
L
L
K
G
A
V
V
L
G
P
S
P
G
Y
V
R
L
L
Q
A
M
K
V
Q
F
E
---
G
G
--------
G
A
V
E
E
Y
T
R
-
L
A
Q
S
G
G
T
S
S
E
V
--
K
M
I
S
L
----
L
N
C
Y
T
V
Q
---
A
A
R
V
S
R
C
S
G
D
K
Q
G
E
L
V
E
---
Q
C
N
K
V
W
L
Q
V
E
K
L
L
Q
E
T
D
L
Q
F
N
P
------------
I
W
E
C
T
V
T
I
L
W
L
----
F
---
S
--
H
F
E
P
F
S
W
N
P
L
P
--
C
S
D
K
Q
R
A
E
Y
--
V
--
S
K
L
-
R
E
F
Y
S
S
N
K
F
V
N
R
F
K
-----
L
-------
K
K
A
L
L
L
Q
I
L
V
N
Y
L
G
G
R
M
LEHD
L
G
E
I
Y
A
I
S
A
K
C
F
D
M
C
R
QQGGM
R
K
V
Q
Y
V
I
G
I
W
H
L
M
N
C
T
V
A
MR
G
K
D
V
A
L
T
N
A
K
L
E
A
L
V
K
Q
I
T
S
45
Fugue
30.81
14%
-46
* C4 *
1EZV
1
CY1_YEAST
D:
[1-198]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
T
A
A
E
H
G
L
H
A
P
A
Y
A
W
S
H
N
G
P
F
E
T
-------
F
D
H
A
S
I
R
R
G
Y
Q
V
Y
R
E
V
C
A
A
C
H
S
L
D
R
V
A
W
R
T
L
V
GVS
H
T
N
E
E
V
R
N
M
A
E
E
F
----
E
-
Y
D
-----
D
E
P
D
--
E
Q
G
N
P
----
K
K
R
P
G
K
L
---
S
D
Y
I
P
G
P
Y
P
N
E
Q
A
A
R
A
A
---
N
Q
G
A
L
P
P
D
L
S
L
I
V
K
A
R
H
G
G
C
D
Y
------------
I
F
S
L
L
T
G
Y
P
D
E
----
P
PAG
V
--
A
L
P
P
G
S
N
Y
N
P
Y
--
F
P
G
G
S
I
A
M
A
--
R
--
V
----
L
F
D
D
M
V
E
Y
E
D
--
G
T
P
A
T
T
S
-------
Q
M
A
K
D
V
T
T
F
L
N
W
C
A
E
P
------------------------------------------------------------------
27
HHSearch
29.90
11%
-49
- C5 -
2Y9U
1
A:
[24-64]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
T
Q
G
L
T
TIYQ
I
---
E
--
H
Y
S
M
D
D
L
A
S
L
K
--
I
P
E
Q
F
R
H
A
I
--
W
--
K
G
I
-
L
D
H
R
Q
L
H
E
F
S
---------------------------------------------------------------------------------------------------
30
HHSearch
29.85
10%
-23
- C5 -
2FYW
-
GCH1L_STRPN
A:
[143-187]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
T
F
W
E
L
---
A
Q
Q
V
K
Q
V
F
D
L
D
S
L
R
M
V
H
Y
Q
E
D
D
L
Q
K
P
I
S
R
V
A
I
C
G
G
S
G
Q
S
F
Y
K
------------
D
A
L
A
K
G
A
D
V
Y
I
----
T
---
G
--
D
I
Y
Y
H
T
A
Q
D
M
L
--
S
D
G
L
L
A
L
D
P
--
G
--
H
Y
I
-
E
V
I
F
V
E
K
I
A
A
L
L
S
Q
W
K
E
D
K
G
-------
W
S
I
D
I
L
P
S
Q
A
S
T
N
P
F
H
------------------------------------------------------------------
11
PsiBlast_PDB
29.65
30%
-25
- C5 -
3VA8
3
?
A:
[174-253]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
W
G
---
G
H
P
G
D
E
D
D
E
Y
G
P
A
L
D
P
E
G
V
V
K
Q
------------
A
K
K
I
I
D
E
Y
G
F
K
----
A
---
I
--
K
L
K
G
G
V
F
P
P
A
D
--
E
V
A
A
I
K
A
L
H
--
K
A
F
P
G
V
-
P
L
R
L
D
-
P
N
A
A
W
T
V
E
T
S
K
W
V
A
-------
K
E
L
E
G
I
V
E
Y
L
E
D
P
A
G
E
------------------------------------------------------------------
32
HHSearch
27.52
24%
-40
- C5 -
1DXS
18
A:
[27-64]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
Q
G
L
Q
S
I
Y
H
L
---
Q
--
N
L
T
I
E
D
L
G
A
L
K
--
I
P
E
Q
Y
R
M
T
I
--
W
--
R
G
L
-
Q
D
L
----------------------------------------------------------------------------------------------------------
42
Fugue
27.45
11%
-41
- C4 -
3KZQ
1
?
A:
[1-206]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M
N
I
K
L
Y
Y
V
H
D
P
M
C
S
W
C
W
G
Y
K
P
T
I
E
K
L
K
Q
Q
L
--
P
G
V
I
Q
F
E
Y
V
V
G
G
L
A
P
D
T
N
L
P
M
P
P
E
M
Q
Q
K
L
E
G
---
I
W
K
Q
I
E
T
Q
L
--
G
T
K
F
N
Y
D
-
F
W
K
L
C
T
P
V
R
S
T
--
Y
Q
S
C
R
----
A
V
I
A
A
G
F
Q
DS
Y
E
Q
M
L
E
A
I
Q
H
A
Y
Y
L
R
A
M
---
P
P
H
E
---------
E
A
T
H
L
Q
L
A
K
------------
E
I
G
L
N
---
V
Q
Q
----
F
---
K
--
N
D
M
D
G
T
L
L
E
G
V
--
F
Q
D
Q
L
S
L
A
K
--
S
--
L
G
V
N
S
Y
P
S
L
V
L
Q
I
N
D
A
Y
F
P
I
E
V
D
Y
-------
L
S
T
E
P
T
L
K
L
I
R
E
R
I
I
E
N
M----------------------------------------------------------------