@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA4148: (2016-02-24 )
MHATSSDDFSLSSRVALVTGAGRGIGRGIALALARAGADVAVADLDPQVAEETAAAIRSLGRRSLALGVDVSDGDSVRAMVERVATEFGRLDVAVNNAGVISIRKVAELSLADWDRVMNVNARGVFLCCQAELPLMQAQRWGRIVNLSSIAGKVGLPDLAHYCASKFAVIGFSNALAKEVARDGVTVNALCPGIVGTGMWRGEDGLSGRWRQAGESEAQSWERHQASLLPQGEAQTVEDMGQLVVYLACAPHVTGQAIAVDGGFSL
Atome Classification :
(36 SA)
.........10........20........30........40....-..-..50........-60....-.....70........80.......------.90........100.......110.......120.......130........-140........150.-.-...-..160.......170.......180.......190.-......------200........210.......220......---.230.......240......--.--250.........260....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MHATSSDDFSLSS
R
V
A
L
V
TGAGRGI
G
R
G
I
A
L
A
L
A
RAGA
D
V
A
V
ADL-
D
P
-
Q
V
A
E
E
T
A
A
A
I
R
S
-L-GRRS-
L
A
L
G
V
DVSD
G
D
S
V
R
A
M
V
E
R
V
A
T
E
F------G
R
L
D
V
A
VNN
A
G
V
I
S
I
R
K
V
A
E
LSLA
D
W
D
R
VMNVNA
R
G
V
F
L
C
CQ-AEL
P
L
M
Q
A
Q
-
R
W-G
R
I
V
N
L
S
S
I
AGK-V-G
L
P
-
D
L
A
H
Y
C
A
S
K
F
A
VIGF
S
N
A
L
A
K
E
V
A
RDG
V
T
V
NALCPG-IVGTGM------W-RGEDGLSG
R
W
RQAG
E
S
E
A
Q
S
W
E
R
H
Q
A
SL---LPQGEA
Q
T
V
E
D
M
G
Q
L
V
V
Y
L
A--C--A--PHVTG
Q
A
I
A
VDGGFSL
22
PsiBlast_CBE
93.46
58%
-105
- C1 -
4WEO
4
?
C:
[13-265]
----------
L
E
G
Q
V
A
I
V
T
G
G
A
R
G
I
G
R
G
I
A
L
T
L
A
G
A
G
A
N
I
L
L
A
D
L
-
L
D
-
D
A
L
D
A
T
A
R
E
V
R
A
-
L
-
G
R
R
A
-
A
I
A
K
V
D
V
T
Q
A
A
Q
V
D
A
M
V
A
Q
A
L
A
D
L
------
G
G
L
D
I
L
V
N
C
A
G
V
I
S
I
H
P
V
A
E
L
T
E
R
D
W
D
F
V
M
N
V
N
A
K
G
T
F
L
G
C
R
-
A
A
L
A
H
L
K
A
Q
-
G
R
-
G
R
I
I
N
V
A
S
I
A
G
K
-
E
-
G
F
P
-
N
L
A
H
Y
S
A
S
K
F
A
V
V
G
F
T
N
A
L
A
K
E
L
A
R
D
G
V
T
V
N
A
I
C
P
G
-
I
V
R
T
--------------------------
V
E
Q
S
W
Q
R
H
Q
L
T
L
---
I
P
Q
G
R
A
Q
T
P
E
D
M
G
R
L
A
L
F
F
A
--
T
--
M
--
D
N
V
T
G
Q
A
V
N
V
D
G
G
F
T
F
21
PsiBlast_CBE
91.39
58%
-105
- C1 -
4WEO
5
?
D:
[13-265]
----------
L
E
G
Q
V
A
I
V
T
G
G
A
R
G
I
G
R
G
I
A
L
T
L
A
G
A
G
A
N
I
L
L
A
D
L
-
L
D
-
D
A
L
D
A
T
A
R
E
V
R
A
-
L
-
G
R
R
A
-
A
I
A
K
V
D
V
T
Q
A
A
Q
V
D
A
M
V
A
Q
A
L
A
D
L
------
G
G
L
D
I
L
V
N
C
A
G
V
I
S
I
H
P
V
A
E
L
T
E
R
D
W
D
F
V
M
N
V
N
A
K
G
T
F
L
G
C
R
-
A
A
L
A
H
L
K
A
Q
-
G
R
-
G
R
I
I
N
V
A
S
I
A
G
K
-
E
-
G
F
P
-
N
L
A
H
Y
S
A
S
K
F
A
V
V
G
F
T
N
A
L
A
K
E
L
A
R
D
G
V
T
V
N
A
I
C
P
G
-
I
V
R
T
-------------------------
S
V
E
Q
S
W
Q
R
H
Q
L
T
L
---
I
P
Q
G
R
A
Q
T
P
E
D
M
G
R
L
A
L
F
F
A
--
T
--
M
--
D
N
V
T
G
Q
A
V
N
V
D
G
G
F
T
F
23
PsiBlast_CBE
91.31
58%
-106
- C1 -
4WEO
4
?
B:
[13-265]
----------
L
E
G
Q
V
A
I
V
T
G
G
A
R
G
I
G
R
G
I
A
L
T
L
A
G
A
G
A
N
I
L
L
A
D
L
-
L
D
-
D
A
L
D
A
T
A
R
E
V
R
A
-
L
-
G
R
R
A
-
A
I
A
K
V
D
V
T
Q
A
A
Q
V
D
A
M
V
A
Q
A
L
A
D
L
------
G
G
L
D
I
L
V
N
C
A
G
V
I
S
I
H
P
V
A
E
L
T
E
R
D
W
D
F
V
M
N
V
N
A
K
G
T
F
L
G
C
R
-
A
A
L
A
H
L
K
A
Q
-
G
R
-
G
R
I
I
N
V
A
S
I
A
G
K
-
E
-
G
F
P
-
N
L
A
H
Y
S
A
S
K
F
A
V
V
G
F
T
N
A
L
A
K
E
L
A
R
D
G
V
T
V
N
A
I
C
P
G
-
I
V
R
---------------------------
V
E
Q
S
W
Q
R
H
Q
L
T
L
---
I
P
Q
G
R
A
Q
T
P
E
D
M
G
R
L
A
L
F
F
A
--
T
--
M
--
D
N
V
T
G
Q
A
V
N
V
D
G
G
F
T
F
1
PsiBlast_PDB
90.16
58%
-107
- C1 -
4WEO
4
?
A:
[13-265]
----------
L
E
G
Q
V
A
I
V
T
G
G
A
R
G
I
G
R
G
I
A
L
T
L
A
G
A
G
A
N
I
L
L
A
D
L
-
L
D
-
D
A
L
D
A
T
A
R
E
V
R
A
-
L
-
G
R
R
A
-
A
I
A
K
V
D
V
T
Q
A
A
Q
V
D
A
M
V
A
Q
A
L
A
D
L
------
G
G
L
D
I
L
V
N
C
A
G
V
I
S
I
H
P
V
A
E
L
T
E
R
D
W
D
F
V
M
N
V
N
A
K
G
T
F
L
G
C
R
-
A
A
L
A
H
L
K
A
Q
-
G
R
-
G
R
I
I
N
V
A
S
I
A
G
K
-
E
-
G
F
P
-
N
L
A
H
Y
S
A
S
K
F
A
V
V
G
F
T
N
A
L
A
K
E
L
A
R
D
G
V
T
V
N
A
I
C
P
G
-
I
V
R
----------------------------
E
Q
S
W
Q
R
H
Q
L
T
L
---
I
P
Q
G
R
A
Q
T
P
E
D
M
G
R
L
A
L
F
F
A
--
T
--
M
--
D
N
V
T
G
Q
A
V
N
V
D
G
G
F
T
F
14
PsiBlast_PDB
84.15
38%
-93
- C1 -
3WYE
1
?
A:
[2-252]
------------
K
K
V
A
L
V
T
G
A
G
Q
G
I
G
K
A
I
A
L
R
L
V
K
D
G
F
A
V
A
I
A
D
Y
-
N
D
-
A
T
A
K
A
V
A
S
E
I
N
Q
-
A
-
G
G
H
A
-
V
A
V
K
V
D
V
S
D
R
D
Q
V
F
A
A
V
E
Q
A
R
K
T
L
------
G
G
F
D
V
I
V
N
N
A
G
I
A
Q
I
K
P
L
L
E
V
T
E
E
D
L
K
Q
I
Y
S
V
N
V
F
S
V
F
F
G
I
Q
-
A
A
V
E
A
F
K
K
E
G
H
G
-
G
K
I
I
N
A
A
S
I
A
A
I
-
Q
-
G
F
P
-
I
L
S
A
Y
S
T
T
K
F
A
V
R
G
L
T
Q
T
A
A
R
D
L
A
P
L
G
I
T
V
N
G
Y
C
P
G
-
I
V
G
T
G
M
------
W
-
E
Q
I
D
A
E
L
S
K
I
N
--
G
K
P
I
G
E
N
F
K
E
Y
S
S
S
----
I
A
L
G
R
P
S
V
P
E
D
V
A
G
L
V
S
F
L
A
--
S
PD
S
--
D
Y
M
T
G
Q
S
L
L
I
D
G
G
---
15
PsiBlast_PDB
83.98
37%
-109
- C1 -
4J2H
7
?
A:
[6-253]
------
P
I
F
D
L
S
G
R
R
A
L
V
T
G
A
S
R
G
I
G
Q
S
I
A
V
A
L
A
E
A
G
A
H
V
A
V
T
A
R
-
T
V
-
E
G
L
A
E
T
R
A
L
I
E
K
-
T
-
G
R
R
A
-
V
A
L
A
Q
D
V
R
D
V
E
A
C
A
S
V
T
R
A
A
A
E
G
L
------
G
G
L
D
I
L
V
N
N
A
G
F
E
N
V
R
P
S
F
D
V
D
E
A
L
W
D
T
I
V
S
T
N
L
K
G
A
F
F
C
A
Q
-
A
A
G
R
I
M
A
D
A
-
N
G
-
G
A
I
V
N
L
C
S
L
T
S
Y
-
V
-
G
I
P
-
T
A
V
P
Y
G
A
S
K
S
G
L
L
G
V
T
R
A
L
A
T
E
W
A
A
H
N
I
R
V
N
A
I
A
P
G
-
Y
F
R
T
A
M
-------------------
T
A
G
F
Y
E
D
E
D
W
Q
S
R
M
L
E
K
---
I
P
Q
R
R
F
G
K
E
S
D
I
G
G
V
A
V
F
L
C
SD
A
--
A
--
A
Y
I
T
G
H
C
I
P
A
D
G
G
Y
--
134
HHSearch
83.45
42%
-97
- C1 -
3WDS
4
?
A:
[7-262]
-------
I
F
D
L
S
G
R
K
A
I
V
T
G
G
S
K
G
I
G
A
A
I
A
R
A
L
D
K
A
G
A
T
V
A
I
A
D
L
-
D
V
-
M
A
A
Q
A
V
V
A
G
L
E
-----
N
G
G
-
F
A
V
E
V
D
V
T
K
R
A
S
V
D
A
A
M
Q
K
A
I
D
A
L
------
G
G
F
D
L
L
C
A
N
A
G
V
S
T
M
R
P
A
V
D
I
T
D
E
E
W
D
F
N
F
D
V
N
A
R
G
V
F
L
A
N
Q
-
I
A
C
R
H
F
L
A
S
N
T
K
-
G
V
I
V
N
T
A
S
L
A
A
K
-
V
-
G
A
P
-
L
L
A
H
Y
S
A
S
K
F
A
V
F
G
W
T
Q
A
L
A
R
E
M
A
P
K
N
I
R
V
N
C
V
C
P
G
-
F
V
K
T
A
M
------
Q
-
E
R
E
I
I
W
E
A
E
L
R
G
---
M
T
P
E
A
V
R
A
E
Y
V
S
L
---
T
P
L
G
R
I
E
E
P
E
D
V
A
D
V
V
V
F
L
A
SD
A
--
A
--
R
F
M
T
G
Q
G
I
N
V
T
G
G
V
R
M
39
PsiBlast_CBE
83.45
39%
-94
- C1 -
1GEG
2
BUDC_KLEPN
F:
[2-253]
------------
K
K
V
A
L
V
T
G
A
G
Q
G
I
G
K
A
I
A
L
R
L
V
K
D
G
F
A
V
A
I
A
D
Y
-
N
D
-
A
T
A
K
A
V
A
S
E
I
N
Q
-
A
-
G
G
H
A
-
V
A
V
K
V
D
V
S
D
R
D
Q
V
F
A
A
V
E
Q
A
R
K
T
L
------
G
G
F
D
V
I
V
N
N
A
G
V
A
P
S
T
P
I
E
S
I
T
P
E
I
V
D
K
V
Y
N
I
N
V
K
G
V
I
W
G
I
Q
-
A
A
V
E
A
F
K
K
E
G
H
G
-
G
K
I
I
N
A
C
S
Q
A
G
H
-
V
-
G
N
P
-
E
L
A
V
Y
S
S
S
K
F
A
V
R
G
L
T
Q
T
A
A
R
D
L
A
P
L
G
I
T
V
N
G
Y
C
P
G
-
I
V
K
T
P
M
------
W
-
A
E
I
D
------
R
Q
V
S
E
A
A
G
K
P
L
G
Y
G
T
A
E
F
AKR
I
T
L
G
R
L
S
E
P
E
D
V
A
A
C
V
S
Y
L
A
--
S
PD
S
--
D
Y
M
T
G
Q
S
L
L
I
D
G
G
M
--
41
PsiBlast_CBE
82.72
39%
-96
- C1 -
1GEG
2
BUDC_KLEPN
D:
[2-253]
------------
K
K
V
A
L
V
T
G
A
G
Q
G
I
G
K
A
I
A
L
R
L
V
K
D
G
F
A
V
A
I
A
D
Y
-
N
D
-
A
T
A
K
A
V
A
S
E
I
N
Q
-
A
-
G
G
H
A
-
V
A
V
K
V
D
V
S
D
R
D
Q
V
F
A
A
V
E
Q
A
R
K
T
L
------
G
G
F
D
V
I
V
N
N
A
G
V
A
P
S
T
P
I
E
S
I
T
P
E
I
V
D
K
V
Y
N
I
N
V
K
G
V
I
W
G
I
Q
-
A
A
V
E
A
F
K
K
E
G
H
G
-
G
K
I
I
N
A
C
S
Q
A
G
H
-
V
-
G
N
P
-
E
L
A
V
Y
S
S
S
K
F
A
V
R
G
L
T
Q
T
A
A
R
D
L
A
P
L
G
I
T
V
N
G
Y
C
P
G
-
I
V
K
T
P
M
------
W
-
A
E
I
D
------
R
Q
V
S
E
A
A
G
K
P
L
G
Y
G
T
A
E
F
AKR
I
T
L
G
R
L
S
E
P
E
D
V
A
A
C
V
S
Y
L
A
--
S
PD
S
--
D
Y
M
T
G
Q
S
L
L
I
D
G
G
M
--
70
PsiBlast_CBE
82.71
34%
-99
- C1 -
2ZTL
3
?
D:
[2-258]
----------
L
K
G
K
V
A
V
V
T
G
S
T
S
G
I
G
L
G
I
A
T
A
L
A
A
Q
G
A
D
I
V
L
N
G
F
G
D
A
-
A
E
I
E
K
V
R
A
G
L
A
A
-
Q
H
G
V
K
V
-
L
Y
D
G
A
D
L
S
K
G
E
A
V
R
G
L
V
D
N
A
V
R
Q
M
------
G
R
I
D
I
L
V
N
N
A
G
I
Q
H
T
A
L
I
E
D
F
P
T
E
K
W
D
A
I
L
A
L
N
L
S
A
V
F
H
G
T
A
-
A
A
L
P
H
M
K
K
Q
-
G
F
-
G
R
I
I
N
I
A
S
A
H
G
L
-
V
-
A
S
A
-
N
K
S
A
Y
V
A
A
K
H
G
V
V
G
F
T
K
V
T
A
L
E
T
A
G
Q
G
I
T
A
N
A
I
C
P
G
-
W
V
R
T
P
L
------
V
---
E
K
Q
I
S
A
L
A
E
K
N
G
V
D
Q
E
T
A
A
R
E
L
L
S
E
K
---
Q
P
S
L
Q
F
V
T
P
E
Q
L
G
G
T
A
V
F
L
A
SD
A
--
A
--
A
Q
I
T
G
T
T
V
S
V
D
G
G
W
T
-
38
PsiBlast_CBE
82.58
39%
-94
- C1 -
1GEG
2
BUDC_KLEPN
G:
[2-253]
------------
K
K
V
A
L
V
T
G
A
G
Q
G
I
G
K
A
I
A
L
R
L
V
K
D
G
F
A
V
A
I
A
D
Y
-
N
D
-
A
T
A
K
A
V
A
S
E
I
N
Q
-
A
-
G
G
H
A
-
V
A
V
K
V
D
V
S
D
R
D
Q
V
F
A
A
V
E
Q
A
R
K
T
L
------
G
G
F
D
V
I
V
N
N
A
G
V
A
P
S
T
P
I
E
S
I
T
P
E
I
V
D
K
V
Y
N
I
N
V
K
G
V
I
W
G
I
Q
-
A
A
V
E
A
F
K
K
E
G
H
G
-
G
K
I
I
N
A
C
S
Q
A
G
H
-
V
-
G
N
P
-
E
L
A
V
Y
S
S
S
K
F
A
V
R
G
L
T
Q
T
A
A
R
D
L
A
P
L
G
I
T
V
N
G
Y
C
P
G
-
I
V
K
T
P
M
------
W
-
A
E
I
D
------
R
Q
V
S
E
A
A
G
K
P
L
G
Y
G
T
A
E
F
AKR
I
T
L
G
R
L
S
E
P
E
D
V
A
A
C
V
S
Y
L
A
--
S
PD
S
--
D
Y
M
T
G
Q
S
L
L
I
D
G
G
M
--
31
PsiBlast_CBE
82.43
41%
-101
- C1 -
3AK4
1
?
C:
[8-262]
--------
F
D
L
S
G
R
K
A
I
V
T
G
G
S
K
G
I
G
A
A
I
A
R
A
L
D
K
A
G
A
T
V
A
I
A
D
L
-
D
V
-
M
A
A
Q
A
V
V
A
G
L
E
N
-
G
-
G
----
F
A
V
E
V
D
V
T
K
R
A
S
V
D
A
A
M
Q
K
A
I
D
A
L
------
G
G
F
D
L
L
C
A
N
A
G
V
S
T
M
R
P
A
V
D
I
T
D
E
E
W
D
F
N
F
D
V
N
A
R
G
V
F
L
A
N
Q
I
A
C
R
H
F
L
A
S
N
-
T
K
-
G
V
I
V
N
T
A
S
L
A
A
K
-
V
-
G
A
P
-
L
L
A
H
Y
S
A
S
K
F
A
V
F
G
W
T
Q
A
L
A
R
E
M
A
P
K
N
I
R
V
N
C
V
C
P
G
-
F
V
K
T
A
M
QEREII
W
-
E
A
E
--
L
R
G
M
T
P
E
A
V
R
A
E
-------
Y
V
S
L
---
T
P
L
G
R
I
E
E
P
E
D
V
A
D
V
V
V
F
L
A
SD
A
--
A
--
R
F
M
T
G
Q
G
I
N
V
T
G
G
V
R
M
44
PsiBlast_CBE
82.40
38%
-104
- C1 -
3WYE
1
?
B:
[3-252]
-------------
K
V
A
L
V
T
G
A
G
Q
G
I
G
K
A
I
A
L
R
L
V
K
D
G
F
A
V
A
I
A
D
Y
-
N
D
-
A
T
A
K
A
V
A
S
E
I
N
Q
-
A
-
G
G
H
A
-
V
A
V
K
V
D
V
S
D
R
D
Q
V
F
A
A
V
E
Q
A
R
K
T
L
------
G
G
F
D
V
I
V
N
N
A
G
I
A
Q
I
K
P
L
L
E
V
T
E
E
D
L
K
Q
I
Y
S
V
N
V
F
S
V
F
F
G
I
Q
-
A
A
V
E
A
F
K
K
E
G
H
G
-
G
K
I
I
N
A
A
S
I
A
A
I
-
Q
-
G
F
P
-
I
L
S
A
Y
S
T
T
K
F
A
V
R
G
L
T
Q
T
A
A
R
D
L
A
P
L
G
I
T
V
N
G
Y
C
P
G
-
I
V
G
T
G
M
------
W
-
E
Q
I
D
A
E
L
S
K
-----------------
S
----
I
A
L
G
R
P
S
V
P
E
D
V
A
G
L
V
S
F
L
A
--
S
PD
S
--
D
Y
M
T
G
Q
S
L
L
I
D
G
G
---
37
PsiBlast_CBE
82.21
39%
-92
- C1 -
1GEG
12
BUDC_KLEPN
H:
[2-253]
------------
K
K
V
A
L
V
T
G
A
G
Q
G
I
G
K
A
I
A
L
R
L
V
K
D
G
F
A
V
A
I
A
D
Y
-
N
D
-
A
T
A
K
A
V
A
S
E
I
N
Q
-
A
-
G
G
H
A
-
V
A
V
K
V
D
V
S
D
R
D
Q
V
F
A
A
V
E
Q
A
R
K
T
L
------
G
G
F
D
V
I
V
N
N
A
G
V
A
P
S
T
P
I
E
S
I
T
P
E
I
V
D
K
V
Y
N
I
N
V
K
G
V
I
W
G
I
Q
-
A
A
V
E
A
F
K
K
E
G
H
G
-
G
K
I
I
N
A
C
S
Q
A
G
H
-
V
-
G
N
P
-
E
L
A
V
Y
S
S
S
K
F
A
V
R
G
L
T
Q
T
A
A
R
D
L
A
P
L
G
I
T
V
N
G
Y
C
P
G
-
I
V
K
T
P
M
------
W
-
A
E
I
D
------
R
Q
V
S
E
A
A
G
K
P
L
G
Y
G
T
A
E
F
AKR
I
T
L
G
R
L
S
E
P
E
D
V
A
A
C
V
S
Y
L
A
--
S
PD
S
--
D
Y
M
T
G
Q
S
L
L
I
D
G
G
M
--
132
HHSearch
82.14
35%
-101
- C1 -
3ICC
5
?
A:
[2-255]
-------
N
S
M
L
K
G
K
V
A
L
V
T
G
A
S
R
G
I
G
R
A
I
A
K
R
L
A
N
D
G
A
L
V
A
I
H
Y
G
-
N
R
K
E
E
A
E
E
T
V
Y
E
I
Q
S
-
N
-
G
G
S
A
-
F
S
I
G
A
N
L
E
S
L
H
G
V
E
A
L
Y
S
S
L
D
N
E
L
Q
N
R
TGS
T
K
F
D
I
L
I
N
N
A
G
I
G
P
G
A
F
I
E
E
T
T
E
Q
F
F
D
R
M
V
S
V
N
A
K
A
P
F
F
I
I
Q
-
Q
A
L
S
R
L
R
D
---
N
-
S
R
I
I
N
I
S
S
A
A
T
R
-
I
-
S
L
P
-
D
F
I
A
Y
S
M
T
K
G
A
I
N
T
M
T
F
T
L
A
K
Q
L
G
A
R
G
I
T
V
N
A
I
L
P
G
-
F
V
K
T
D
M
------
N
-
A
E
L
L
S
D
P
M
-
M
-------
K
Q
----
Y
A
T
T
I
---
S
A
F
N
R
L
G
E
V
E
D
I
A
D
T
A
A
F
L
A
SP
D
--
S
--
R
W
V
T
G
Q
L
I
D
V
S
G
G
S
C
L
71
PsiBlast_CBE
82.14
34%
-99
- C1 -
2ZTL
2
?
C:
[2-258]
----------
L
K
G
K
V
A
V
V
T
G
S
T
S
G
I
G
L
G
I
A
T
A
L
A
A
Q
G
A
D
I
V
L
N
G
F
G
D
A
-
A
E
I
E
K
V
R
A
G
L
A
A
-
Q
H
G
V
K
V
-
L
Y
D
G
A
D
L
S
K
G
E
A
V
R
G
L
V
D
N
A
V
R
Q
M
------
G
R
I
D
I
L
V
N
N
A
G
I
Q
H
T
A
L
I
E
D
F
P
T
E
K
W
D
A
I
L
A
L
N
L
S
A
V
F
H
G
T
A
-
A
A
L
P
H
M
K
K
Q
-
G
F
-
G
R
I
I
N
I
A
S
A
H
G
L
-
V
-
A
S
A
-
N
K
S
A
Y
V
A
A
K
H
G
V
V
G
F
T
K
V
T
A
L
E
T
A
G
Q
G
I
T
A
N
A
I
C
P
G
-
W
V
R
T
P
L
------
V
---
E
K
Q
I
S
A
L
A
E
K
N
G
V
D
Q
E
T
A
A
R
E
L
L
S
E
K
---
Q
P
S
L
Q
F
V
T
P
E
Q
L
G
G
T
A
V
F
L
A
SD
A
--
A
--
A
Q
I
T
G
T
T
V
S
V
D
G
G
W
T
-
42
PsiBlast_CBE
81.88
39%
-96
- C1 -
1GEG
2
BUDC_KLEPN
C:
[2-253]
------------
K
K
V
A
L
V
T
G
A
G
Q
G
I
G
K
A
I
A
L
R
L
V
K
D
G
F
A
V
A
I
A
D
Y
-
N
D
-
A
T
A
K
A
V
A
S
E
I
N
Q
-
A
-
G
G
H
A
-
V
A
V
K
V
D
V
S
D
R
D
Q
V
F
A
A
V
E
Q
A
R
K
T
L
------
G
G
F
D
V
I
V
N
N
A
G
V
A
P
S
T
P
I
E
S
I
T
P
E
I
V
D
K
V
Y
N
I
N
V
K
G
V
I
W
G
I
Q
-
A
A
V
E
A
F
K
K
E
G
H
G
-
G
K
I
I
N
A
C
S
Q
A
G
H
-
V
-
G
N
P
-
E
L
A
V
Y
S
S
S
K
F
A
V
R
G
L
T
Q
T
A
A
R
D
L
A
P
L
G
I
T
V
N
G
Y
C
P
G
-
I
V
K
T
P
M
------
W
-
A
E
I
D
------
R
Q
V
S
E
A
A
G
K
P
L
G
Y
G
T
A
E
F
AKR
I
T
L
G
R
L
S
E
P
E
D
V
A
A
C
V
S
Y
L
A
--
S
PD
S
--
D
Y
M
T
G
Q
S
L
L
I
D
G
G
M
--
62
PsiBlast_CBE
81.85
33%
-113
- C1 -
3R1I
1
?
A:
[26-274]
------
D
L
F
D
L
S
G
K
R
A
L
I
T
G
A
S
T
G
I
G
K
K
V
A
L
A
Y
A
E
A
G
A
Q
V
A
V
A
A
R
-
H
S
-
D
A
L
Q
V
V
A
D
E
I
A
G
-
V
-
G
G
K
A
-
L
P
I
R
C
D
V
T
Q
P
D
Q
V
R
G
M
L
D
Q
M
T
G
E
L
------
G
G
I
D
I
A
V
C
N
A
G
I
V
S
V
Q
A
M
L
D
M
P
L
E
E
F
Q
R
I
Q
D
T
N
V
T
G
V
F
L
T
A
Q
-
A
A
A
R
A
M
V
D
Q
-
G
L
G
G
T
I
I
T
T
A
S
M
S
G
H
I
I
-
N
I
P
Q
Q
V
S
H
Y
C
T
S
K
A
A
V
V
H
L
T
K
A
M
A
V
E
L
A
P
H
Q
I
R
V
N
S
V
S
P
G
-
Y
I
R
T
E
L
------
V
-
E
P
L
A
D
Y
H
A
L
W
E
P
K
------------------
I
P
L
G
R
M
G
R
P
E
E
L
T
G
L
Y
L
Y
L
A
--
S
--
A
AS
S
Y
M
T
G
S
D
I
V
I
D
G
G
Y
T
-
3
PsiBlast_PDB
81.71
37%
-103
- C1 -
2UVD
-
?
A:
[2-246]
----------
L
K
G
K
V
A
L
V
T
G
A
S
R
G
I
G
R
A
I
A
I
D
L
A
K
Q
G
A
N
V
V
V
N
Y
A
G
N
E
-
Q
K
A
N
E
V
V
D
E
I
K
K
-
L
-
G
S
D
A
-
I
A
V
R
A
D
V
A
N
A
E
D
V
T
N
M
V
K
Q
T
V
D
V
F
------
G
Q
V
D
I
L
V
N
N
A
G
V
T
K
D
N
L
L
M
R
M
K
E
E
E
W
D
T
V
I
N
T
N
L
K
G
V
F
L
C
T
K
-
A
V
S
R
F
M
M
R
Q
-
R
H
-
G
R
I
V
N
I
A
S
V
V
G
V
-
T
-
G
N
P
-
G
Q
A
N
Y
V
A
A
K
A
G
V
I
G
L
T
K
T
S
A
K
E
L
A
S
R
N
I
T
V
N
A
I
A
P
G
-
F
I
A
T
D
M
------
T
-
D
V
L
D
--------------
E
N
I
K
A
E
M
L
K
L
---
I
P
A
A
Q
F
G
E
A
Q
D
I
A
N
A
V
T
F
F
A
--
S
DQ
S
--
K
Y
I
T
G
Q
T
L
N
V
D
G
G
M
V
M
6
PsiBlast_PDB
81.62
41%
-101
- C1 -
3AK4
1
?
A:
[8-262]
--------
F
D
L
S
G
R
K
A
I
V
T
G
G
S
K
G
I
G
A
A
I
A
R
A
L
D
K
A
G
A
T
V
A
I
A
D
L
-
D
V
-
M
A
A
Q
A
V
V
A
G
L
E
N
-
G
-
G
----
F
A
V
E
V
D
V
T
K
R
A
S
V
D
A
A
M
Q
K
A
I
D
A
L
------
G
G
F
D
L
L
C
A
N
A
G
V
S
T
M
R
P
A
V
D
I
T
D
E
E
W
D
F
N
F
D
V
N
A
R
G
V
F
L
A
N
Q
I
A
C
R
H
F
L
A
S
N
-
T
K
-
G
V
I
V
N
T
A
S
L
A
A
K
-
V
-
G
A
P
-
L
L
A
H
Y
S
A
S
K
F
A
V
F
G
W
T
Q
A
L
A
R
E
M
A
P
K
N
I
R
V
N
C
V
C
P
G
-
F
V
K
T
A
M
Q
E
R
E
I
I
W
-
E
A
E
--
L
R
G
M
T
P
E
A
V
R
A
E
-------
Y
V
S
L
---
T
P
L
G
R
I
E
E
P
E
D
V
A
D
V
V
V
F
L
A
SD
A
--
A
--
R
F
M
T
G
Q
G
I
N
V
T
G
G
V
R
M
29
PsiBlast_CBE
81.03
41%
-101
- C1 -
3WDS
3
?
B:
[8-262]
--------
F
D
L
S
G
R
K
A
I
V
T
G
G
S
K
G
I
G
A
A
I
A
R
A
L
D
K
A
G
A
T
V
A
I
A
D
L
-
D
V
-
M
A
A
Q
A
V
V
A
G
L
E
N
-
G
-
G
----
F
A
V
E
V
D
V
T
K
R
A
S
V
D
A
A
M
Q
K
A
I
D
A
L
------
G
G
F
D
L
L
C
A
N
A
G
V
S
T
M
R
P
A
V
D
I
T
D
E
E
W
D
F
N
F
D
V
N
A
R
G
V
F
L
A
N
Q
I
A
C
R
H
F
L
A
S
N
-
T
K
-
G
V
I
V
N
T
A
S
L
A
A
K
-
V
-
G
A
P
-
L
L
A
H
Y
S
A
S
K
F
A
V
F
G
W
T
Q
A
L
A
R
E
M
A
P
K
N
I
R
V
N
C
V
C
P
G
-
F
V
K
T
A
M
QEREII
W
-
E
A
E
--
L
R
G
M
T
P
E
A
V
R
A
E
-------
Y
V
S
L
---
T
P
L
G
R
I
E
E
P
E
D
V
A
D
V
V
V
F
L
A
SD
A
--
A
--
R
F
M
T
G
Q
G
I
N
V
T
G
G
V
R
M
28
PsiBlast_CBE
80.72
41%
-100
- C1 -
3WDS
3
?
C:
[8-262]
--------
F
D
L
S
G
R
K
A
I
V
T
G
G
S
K
G
I
G
A
A
I
A
R
A
L
D
K
A
G
A
T
V
A
I
A
D
L
-
D
V
-
M
A
A
Q
A
V
V
A
G
L
E
N
-
G
-
G
----
F
A
V
E
V
D
V
T
K
R
A
S
V
D
A
A
M
Q
K
A
I
D
A
L
------
G
G
F
D
L
L
C
A
N
A
G
V
S
T
M
R
P
A
V
D
I
T
D
E
E
W
D
F
N
F
D
V
N
A
R
G
V
F
L
A
N
Q
I
A
C
R
H
F
L
A
S
N
-
T
K
-
G
V
I
V
N
T
A
S
L
A
A
K
-
V
-
G
A
P
-
L
L
A
H
Y
S
A
S
K
F
A
V
F
G
W
T
Q
A
L
A
R
E
M
A
P
K
N
I
R
V
N
C
V
C
P
G
-
F
V
K
T
A
M
QEREII
W
-
E
A
E
--
L
R
G
M
T
P
E
A
V
R
A
E
-------
Y
V
S
L
---
T
P
L
G
R
I
E
E
P
E
D
V
A
D
V
V
V
F
L
A
SD
A
--
A
--
R
F
M
T
G
Q
G
I
N
V
T
G
G
V
R
M
30
PsiBlast_CBE
80.69
41%
-102
- C1 -
3AK4
1
?
D:
[8-262]
--------
F
D
L
S
G
R
K
A
I
V
T
G
G
S
K
G
I
G
A
A
I
A
R
A
L
D
K
A
G
A
T
V
A
I
A
D
L
-
D
V
-
M
A
A
Q
A
V
V
A
G
L
E
N
-
G
-
G
----
F
A
V
E
V
D
V
T
K
R
A
S
V
D
A
A
M
Q
K
A
I
D
A
L
------
G
G
F
D
L
L
C
A
N
A
G
V
S
T
M
R
P
A
V
D
I
T
D
E
E
W
D
F
N
F
D
V
N
A
R
G
V
F
L
A
N
Q
I
A
C
R
H
F
L
A
S
N
-
T
K
-
G
V
I
V
N
T
A
S
L
A
A
K
-
V
-
G
A
P
-
L
L
A
H
Y
S
A
S
K
F
A
V
F
G
W
T
Q
A
L
A
R
E
M
A
P
K
N
I
R
V
N
C
V
C
P
G
-
F
V
K
T
A
M
QEREII
W
-
E
A
E
--
L
R
G
M
T
P
E
A
V
R
A
E
-------
Y
V
S
L
---
T
P
L
G
R
I
E
E
P
E
D
V
A
D
V
V
V
F
L
A
SD
A
--
A
--
R
F
M
T
G
Q
G
I
N
V
T
G
G
V
R
M
10
PsiBlast_PDB
80.44
38%
-104
- C1 -
3OSU
15
FABG_STAAM
A:
[4-243]
------------
T
K
S
A
L
V
T
G
A
S
R
G
I
G
R
S
I
A
L
Q
L
A
E
E
G
Y
N
V
A
V
N
Y
A
G
S
K
-
E
K
A
E
A
V
V
E
E
I
K
A
-
K
-
G
V
D
S
-
F
A
I
Q
A
N
V
A
D
A
D
E
V
K
A
M
I
K
E
V
V
S
Q
F
------
G
S
L
D
V
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
E
Q
E
W
D
D
V
I
D
T
N
L
K
G
V
F
N
C
I
Q
-
K
A
T
P
Q
M
L
R
Q
-
R
S
-
G
A
I
I
N
L
S
S
V
V
G
A
-
V
-
G
N
P
-
G
Q
A
N
Y
V
A
T
K
A
G
V
I
G
L
T
K
S
A
A
R
E
L
A
S
R
G
I
T
V
N
A
V
A
P
G
-
F
I
---
V
------
S
-
D
M
T
D
A
L
S
D
E
L
K
E
-----------
Q
M
L
T
Q
---
I
P
L
A
R
F
G
Q
D
T
D
I
A
N
T
V
A
F
L
A
--
S
DK
A
--
K
Y
I
T
G
Q
T
I
H
V
N
G
G
---
45
PsiBlast_CBE
80.37
34%
-113
- C1 -
4NBU
2
?
D:
[11-250]
----------
L
Q
D
K
V
A
I
I
T
G
A
A
N
G
I
G
L
E
A
A
R
V
F
M
K
E
G
A
K
V
V
I
A
D
F
-
N
E
-
A
A
G
K
E
A
V
E
A
N
P
G
-
V
------
V
F
I
R
V
D
V
S
D
R
E
S
V
H
R
L
V
E
N
V
A
E
R
F
------
G
K
I
D
I
L
I
N
N
A
G
I
T
R
D
S
M
L
S
K
M
T
V
D
Q
F
Q
Q
V
I
N
V
N
L
T
G
V
F
H
C
T
Q
-
A
V
L
P
Y
M
A
E
Q
-
G
K
-
G
K
I
I
N
T
S
S
V
T
G
T
-
Y
-
G
N
V
-
G
Q
T
N
Y
A
A
A
K
A
G
V
I
G
M
T
K
T
W
A
K
E
L
A
R
K
G
I
N
V
N
A
V
A
P
G
-
F
T
E
T
A
M
--------------------
V
A
E
V
P
E
K
V
I
E
K
M
K
A
Q
----
V
P
M
G
R
L
G
K
P
E
D
I
A
N
A
Y
L
F
L
A
--
S
HE
S
--
D
Y
V
N
G
H
V
L
H
V
D
G
G
I
M
M
88
PsiBlast_CBE
80.02
39%
-106
- C1 -
3RIH
5
?
D:
[37-281]
--------
F
D
L
S
A
R
S
V
L
V
T
G
G
T
K
G
I
G
R
G
I
A
T
V
F
A
R
A
G
A
N
V
A
V
A
A
R
-
S
P
-
R
E
L
S
S
V
T
A
E
L
G
E
-
L
-
G
A
G
N
V
I
G
V
R
L
D
V
S
D
P
G
S
C
A
D
A
A
R
T
V
V
D
A
F
------
G
A
L
D
V
V
C
A
N
A
G
I
F
P
E
A
R
L
D
T
M
T
P
E
Q
L
S
E
V
L
D
V
N
V
K
G
T
V
Y
T
V
Q
-
A
C
L
A
P
L
T
A
S
-
G
R
-
G
R
V
I
L
T
S
S
I
T
G
P
-
V
T
G
Y
P
-
G
W
S
H
Y
G
A
S
K
A
A
Q
L
G
F
M
R
T
A
A
I
E
L
A
P
R
G
V
T
V
N
A
I
L
P
G
N
I
L
T
E
G
L
------
V
D
M
G
E
E
Y
I
S
G
M
A
R
S
-------------------
I
P
M
G
M
L
G
S
P
V
D
I
G
H
L
A
A
F
L
A
--
T
DE
A
--
G
Y
I
T
G
Q
A
I
V
V
D
G
G
---
32
PsiBlast_CBE
79.52
41%
-100
- C1 -
3AK4
1
?
B:
[8-262]
--------
F
D
L
S
G
R
K
A
I
V
T
G
G
S
K
G
I
G
A
A
I
A
R
A
L
D
K
A
G
A
T
V
A
I
A
D
L
-
D
V
-
M
A
A
Q
A
V
V
A
G
L
E
N
-
G
-
G
----
F
A
V
E
V
D
V
T
K
R
A
S
V
D
A
A
M
Q
K
A
I
D
A
L
------
G
G
F
D
L
L
C
A
N
A
G
V
S
T
M
R
P
A
V
D
I
T
D
E
E
W
D
F
N
F
D
V
N
A
R
G
V
F
L
A
N
Q
I
A
C
R
H
F
L
A
S
N
-
T
K
-
G
V
I
V
N
T
A
S
L
A
A
K
-
V
-
G
A
P
-
L
L
A
H
Y
S
A
S
K
F
A
V
F
G
W
T
Q
A
L
A
R
E
M
A
P
K
N
I
R
V
N
C
V
C
P
G
-
F
V
K
T
A
M
QEREII
W
-
E
A
E
--
L
R
G
M
T
P
E
A
V
R
A
E
-------
Y
V
S
L
---
T
P
L
G
R
I
E
E
P
E
D
V
A
D
V
V
V
F
L
A
SD
A
--
A
--
R
F
M
T
G
Q
G
I
N
V
T
G
G
V
R
M
7
PsiBlast_PDB
79.37
41%
-101
- C1 -
3WDS
4
?
A:
[8-262]
--------
F
D
L
S
G
R
K
A
I
V
T
G
G
S
K
G
I
G
A
A
I
A
R
A
L
D
K
A
G
A
T
V
A
I
A
D
L
-
D
V
-
M
A
A
Q
A
V
V
A
G
L
E
N
-
G
-
G
----
F
A
V
E
V
D
V
T
K
R
A
S
V
D
A
A
M
Q
K
A
I
D
A
L
------
G
G
F
D
L
L
C
A
N
A
G
V
S
T
M
R
P
A
V
D
I
T
D
E
E
W
D
F
N
F
D
V
N
A
R
G
V
F
L
A
N
Q
I
A
C
R
H
F
L
A
S
N
-
T
K
-
G
V
I
V
N
T
A
S
L
A
A
K
-
V
-
G
A
P
-
L
L
A
H
Y
S
A
S
K
F
A
V
F
G
W
T
Q
A
L
A
R
E
M
A
P
K
N
I
R
V
N
C
V
C
P
G
-
F
V
K
T
A
M
Q
E
R
E
I
I
W
-
E
A
E
--
L
R
G
M
T
P
E
A
V
R
A
E
-------
Y
V
S
L
---
T
P
L
G
R
I
E
E
P
E
D
V
A
D
V
V
V
F
L
A
SD
A
--
A
--
R
F
M
T
G
Q
G
I
N
V
T
G
G
V
R
M
46
PsiBlast_CBE
79.16
34%
-113
- C1 -
4NBU
1
?
C:
[11-250]
----------
L
Q
D
K
V
A
I
I
T
G
A
A
N
G
I
G
L
E
A
A
R
V
F
M
K
E
G
A
K
V
V
I
A
D
F
-
N
E
-
A
A
G
K
E
A
V
E
A
N
P
G
-
V
------
V
F
I
R
V
D
V
S
D
R
E
S
V
H
R
L
V
E
N
V
A
E
R
F
------
G
K
I
D
I
L
I
N
N
A
G
I
T
R
D
S
M
L
S
K
M
T
V
D
Q
F
Q
Q
V
I
N
V
N
L
T
G
V
F
H
C
T
Q
-
A
V
L
P
Y
M
A
E
Q
-
G
K
-
G
K
I
I
N
T
S
S
V
T
G
T
-
Y
-
G
N
V
-
G
Q
T
N
Y
A
A
A
K
A
G
V
I
G
M
T
K
T
W
A
K
E
L
A
R
K
G
I
N
V
N
A
V
A
P
G
-
F
T
E
T
A
M
--------------------
V
A
E
V
P
E
K
V
I
E
K
M
K
A
Q
----
V
P
M
G
R
L
G
K
P
E
D
I
A
N
A
Y
L
F
L
A
--
S
HE
S
--
D
Y
V
N
G
H
V
L
H
V
D
G
G
I
M
M
89
PsiBlast_CBE
79.15
39%
-106
- C1 -
3RIH
7
?
C:
[37-281]
--------
F
D
L
S
A
R
S
V
L
V
T
G
G
T
K
G
I
G
R
G
I
A
T
V
F
A
R
A
G
A
N
V
A
V
A
A
R
-
S
P
-
R
E
L
S
S
V
T
A
E
L
G
E
-
L
-
G
A
G
N
V
I
G
V
R
L
D
V
S
D
P
G
S
C
A
D
A
A
R
T
V
V
D
A
F
------
G
A
L
D
V
V
C
A
N
A
G
I
F
P
E
A
R
L
D
T
M
T
P
E
Q
L
S
E
V
L
D
V
N
V
K
G
T
V
Y
T
V
Q
-
A
C
L
A
P
L
T
A
S
-
G
R
-
G
R
V
I
L
T
S
S
I
T
G
P
-
V
T
G
Y
P
-
G
W
S
H
Y
G
A
S
K
A
A
Q
L
G
F
M
R
T
A
A
I
E
L
A
P
R
G
V
T
V
N
A
I
L
P
G
N
I
L
T
E
G
L
------
V
D
M
G
E
E
Y
I
S
G
M
A
R
S
-------------------
I
P
M
G
M
L
G
S
P
V
D
I
G
H
L
A
A
F
L
A
--
T
DE
A
--
G
Y
I
T
G
Q
A
I
V
V
D
G
G
---
16
PsiBlast_PDB
78.87
34%
-113
- C1 -
4NBU
1
?
A:
[11-250]
----------
L
Q
D
K
V
A
I
I
T
G
A
A
N
G
I
G
L
E
A
A
R
V
F
M
K
E
G
A
K
V
V
I
A
D
F
-
N
E
-
A
A
G
K
E
A
V
E
A
N
P
G
-
V
------
V
F
I
R
V
D
V
S
D
R
E
S
V
H
R
L
V
E
N
V
A
E
R
F
------
G
K
I
D
I
L
I
N
N
A
G
I
T
R
D
S
M
L
S
K
M
T
V
D
Q
F
Q
Q
V
I
N
V
N
L
T
G
V
F
H
C
T
Q
-
A
V
L
P
Y
M
A
E
Q
-
G
K
-
G
K
I
I
N
T
S
S
V
T
G
T
-
Y
-
G
N
V
-
G
Q
T
N
Y
A
A
A
K
A
G
V
I
G
M
T
K
T
W
A
K
E
L
A
R
K
G
I
N
V
N
A
V
A
P
G
-
F
T
E
T
A
M
--------------------
V
A
E
V
P
E
K
V
I
E
K
M
K
A
Q
----
V
P
M
G
R
L
G
K
P
E
D
I
A
N
A
Y
L
F
L
A
--
S
HE
S
--
D
Y
V
N
G
H
V
L
H
V
D
G
G
I
M
M
91
PsiBlast_CBE
78.41
39%
-105
- C1 -
3RIH
10
?
A:
[37-281]
--------
F
D
L
S
A
R
S
V
L
V
T
G
G
T
K
G
I
G
R
G
I
A
T
V
F
A
R
A
G
A
N
V
A
V
A
A
R
-
S
P
-
R
E
L
S
S
V
T
A
E
L
G
E
-
L
-
G
A
G
N
V
I
G
V
R
L
D
V
S
D
P
G
S
C
A
D
A
A
R
T
V
V
D
A
F
------
G
A
L
D
V
V
C
A
N
A
G
I
F
P
E
A
R
L
D
T
M
T
P
E
Q
L
S
E
V
L
D
V
N
V
K
G
T
V
Y
T
V
Q
-
A
C
L
A
P
L
T
A
S
-
G
R
-
G
R
V
I
L
T
S
S
I
T
G
P
-
V
T
G
Y
P
-
G
W
S
H
Y
G
A
S
K
A
A
Q
L
G
F
M
R
T
A
A
I
E
L
A
P
R
G
V
T
V
N
A
I
L
P
G
N
I
L
T
E
G
L
------
V
D
M
G
E
E
Y
I
S
G
M
A
R
S
-------------------
I
P
M
G
M
L
G
S
P
V
D
I
G
H
L
A
A
F
L
A
--
T
DE
A
--
G
Y
I
T
G
Q
A
I
V
V
D
G
G
---
90
PsiBlast_CBE
77.87
39%
-104
- C1 -
3RIH
11
?
B:
[37-281]
--------
F
D
L
S
A
R
S
V
L
V
T
G
G
T
K
G
I
G
R
G
I
A
T
V
F
A
R
A
G
A
N
V
A
V
A
A
R
-
S
P
-
R
E
L
S
S
V
T
A
E
L
G
E
-
L
-
G
A
G
N
V
I
G
V
R
L
D
V
S
D
P
G
S
C
A
D
A
A
R
T
V
V
D
A
F
------
G
A
L
D
V
V
C
A
N
A
G
I
F
P
E
A
R
L
D
T
M
T
P
E
Q
L
S
E
V
L
D
V
N
V
K
G
T
V
Y
T
V
Q
-
A
C
L
A
P
L
T
A
S
-
G
R
-
G
R
V
I
L
T
S
S
I
T
G
P
-
V
T
G
Y
P
-
G
W
S
H
Y
G
A
S
K
A
A
Q
L
G
F
M
R
T
A
A
I
E
L
A
P
R
G
V
T
V
N
A
I
L
P
G
N
I
L
T
E
G
L
------
V
D
M
G
E
E
Y
I
S
G
M
A
R
S
-------------------
I
P
M
G
M
L
G
S
P
V
D
I
G
H
L
A
A
F
L
A
--
T
DE
A
--
G
Y
I
T
G
Q
A
I
V
V
D
G
G
---
97
PsiBlast_CBE
70.41
33%
-109
- C1 -
4I08
6
FABG_VIBCH
A:
[5-250]
-----
S
Q
F
M
N
L
E
G
K
V
A
L
V
T
G
A
S
R
G
I
G
K
A
I
A
E
L
L
A
E
R
G
A
K
V
----
I
-
G
T
-
A
T
S
E
S
G
A
Q
A
I
S
D
Y
L
-
G
D
N
G
-
K
G
M
A
L
N
V
T
N
P
E
S
I
E
A
V
L
K
A
I
T
D
E
F
------
G
G
V
D
I
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
E
E
E
W
S
D
I
M
E
T
N
L
T
S
I
F
R
L
S
K
-
A
V
L
R
G
M
M
K
K
-
R
Q
-
G
R
I
I
N
V
G
S
V
V
G
T
-
M
-
G
N
A
-
G
Q
A
N
Y
A
A
A
K
A
G
V
I
G
F
T
K
S
M
A
R
E
V
A
S
R
G
V
T
V
N
T
V
A
P
G
-
F
I
E
T
D
M
---------------------------
N
D
E
Q
R
T
A
T
L
A
Q
-
V
P
A
G
R
L
G
D
P
R
E
I
A
S
A
V
A
F
L
A
--
S
PE
A
--
A
Y
I
T
G
E
T
L
H
V
N
G
G
M
Y
M
101
PsiBlast_CBE
68.05
33%
-104
- C1 -
3RRO
11
FABG_VIBCH
A:
[5-250]
-----
S
Q
F
M
N
L
E
G
K
V
A
L
V
T
G
A
S
R
G
I
G
K
A
I
A
E
L
L
A
E
R
G
A
K
V
----
I
-
G
T
-
A
T
S
E
S
G
A
Q
A
I
S
D
Y
L
-
G
D
N
G
-
K
G
M
A
L
N
V
T
N
P
E
S
I
E
A
V
L
K
A
I
T
D
E
F
------
G
G
V
D
I
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
E
E
E
W
S
D
I
M
E
T
N
L
T
S
I
F
R
L
S
K
-
A
V
L
R
G
M
M
K
K
-
R
Q
-
G
R
I
I
N
V
G
S
V
V
G
T
-
M
-
G
N
A
-
G
Q
A
N
Y
A
A
A
K
A
G
V
I
G
F
T
K
S
M
A
R
E
V
A
S
R
G
V
T
V
N
T
V
A
P
G
-
F
I
E
T
D
M
-----------------------
T
K
A
L
N
D
E
Q
R
T
A
T
L
A
Q
-
V
P
A
G
R
L
G
D
P
R
E
I
A
S
A
V
A
F
L
A
--
S
PE
A
--
A
Y
I
T
G
E
T
L
H
V
N
G
G
M
Y
M
100
PsiBlast_CBE
67.10
33%
-104
- C1 -
3RRO
13
FABG_VIBCH
B:
[5-250]
-----
S
Q
F
M
N
L
E
G
K
V
A
L
V
T
G
A
S
R
G
I
G
K
A
I
A
E
L
L
A
E
R
G
A
K
V
----
I
-
G
T
-
A
T
S
E
S
G
A
Q
A
I
S
D
Y
L
-
G
D
N
G
-
K
G
M
A
L
N
V
T
N
P
E
S
I
E
A
V
L
K
A
I
T
D
E
F
------
G
G
V
D
I
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
E
E
E
W
S
D
I
M
E
T
N
L
T
S
I
F
R
L
S
K
-
A
V
L
R
G
M
M
K
K
-
R
Q
-
G
R
I
I
N
V
G
S
V
V
G
T
-
M
-
G
N
A
-
G
Q
A
N
Y
A
A
A
K
A
G
V
I
G
F
T
K
S
M
A
R
E
V
A
S
R
G
V
T
V
N
T
V
A
P
G
-
F
I
E
T
D
M
-----------------------
T
K
A
L
N
D
E
Q
R
T
A
T
L
AQ-
V
P
A
G
R
L
G
D
P
R
E
I
A
S
A
V
A
F
L
A
--
S
PE
A
--
A
Y
I
T
G
E
T
L
H
V
N
G
G
M
Y
M