@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA5070: (2016-03-04 )
MSADKPEQPEHDQEMPLVSHLTELRTRLLRSVAAIFLIFAGLFYFSQKIYTLVSEPLRRFLPEGTSMIATDVASPFLAPFKLTMVVALFLAMPVILAQVWGFIAPGLYKHEKRVALPLLVSSIILFYAGMAFAYFLVFPMIFHFFASVTPEGVAMMTDINSYLDFVLTLFFAFGVAFEIPVATVLLIWIGVVDVDYLKKIRPYVIIGCFVVGMVLTPPDIFSQTMLAVPMWLLFEIGLLFGRLVRKRGEHPDDQPASDGDQPPATRQ
Atome Classification :
(20 SA)
----........-------.10........20.......-----.30........40.-.......50.....------...60........70.......----------------.80........90.----------------.......100.......110.......120-------..----......130.......140-........--.150.----......160-----...----....170.......180....-..------------------------------.--------------------------190.......200--------------.......--.-----210-------.--------.......220.......--230....-----...240..---...---..250.......260.....-------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----MSADKPEQ-------PEHDQEM
P
L
V
S
H
L
T
E
L
R
T
R
L
-----
L
R
S
V
A
A
I
F
L
I
F
A
G
L
-
F
Y
F
S
Q
K
I
Y
T
L
V
S
E
P
------
L
R
R
FLPEGTS
M
I
A
T
DVAS
P
F
L
A
----------------
P
F
K
L
T
M
V
V
A
L
F
L
A
M
----------------
P
V
I
L
A
Q
V
W
G
F
IAP
G
L
Y
K
H
EKR
V
A
L
P
L
L
V
S
--------
S
I
----
I
L
F
Y
A
G
M
A
F
A
Y
F
L
V
F
P
M
---
I
F
H
F
F
A
SV--TPEGV----
A
M
M
T
D
I
N
S
Y
-----
L
D
F
----
V
L
T
L
F
F
A
F
G
V
A
FE
I
P
V
A
T
V
L
L
-
I
W
------------------------------
I
--------------------------
G
VV
D
V
D
Y
L
KKIR---------------
P
Y
V
I
I
G
C
--
F
-----
V
V--------G--------MVLT
P
P
D
I
F
S
Q
T
M
L
A
V
P
--
M
W
L
L
F
E
I
-----
G
L
L
F
G
R
L
V
---
R
KR---GEHPDDQPASDGDQPPATRQ-------------------------------------
1
PsiBlast_PDB
86.75
37%
-201
- C7 -
4B4A
1
TATC_AQUAE
A:
[5-229]
-----------------------------
E
H
L
R
E
L
R
Y
R
L
-----
I
I
S
I
I
A
-
F
L
I
G
S
G
I
A
F
Y
F
A
K
Y
V
F
E
I
L
K
E
P
------
I
L
K
S
Y
P
E
-
V
E
L
I
T
L
S
P
T
E
P
L
F
I
----------------
L
I
K
I
S
L
A
V
G
F
I
I
A
S
----------------
P
V
I
L
Y
Q
F
W
R
F
I
E
P
A
L
Y
S
H
E
K
R
A
F
I
P
L
L
L
G
--------
S
I
----
L
L
F
M
L
G
A
L
F
A
Y
F
I
V
L
P
L
---
A
L
K
F
L
L
G
L
GF
T
Q
L
L
A
----
T
P
Y
L
S
V
D
M
Y
-----
I
S
F
----
V
L
K
L
V
V
A
F
G
I
A
F
E
M
P
I
V
L
Y
V
L
-
Q
K
------------------------------
A
--------------------------
G
V
I
T
P
E
Q
L
A
S
F
R
---------------
K
Y
F
I
V
I
A
--
F
-----
V
I
--------
G
--------
A
I
I
A
-
P
D
V
S
T
Q
V
L
M
A
I
P
--
L
L
L
L
Y
E
I
-----
S
I
F
L
G
K
L
-------------------------------------------------------------------
2
PsiBlast_PDB
86.40
39%
-201
- C7 -
4HTT
-
ENLYS_BPT4 (first)
A:
[7-231]
-----------------------------
E
H
L
R
E
L
R
Y
R
L
-----
I
I
S
I
I
A
-
F
L
I
G
S
G
I
A
F
Y
F
A
K
Y
V
F
E
I
L
K
E
P
------
I
L
K
S
Y
P
E
-
V
E
L
I
T
L
S
P
T
E
P
L
F
I
----------------
L
I
K
I
S
L
A
V
G
F
I
I
A
S
----------------
P
V
I
L
Y
Q
F
W
R
F
I
E
P
A
L
Y
S
H
E
K
R
A
F
I
P
L
L
L
G
--------
S
I
----
L
L
F
M
L
G
A
L
F
A
Y
F
I
V
L
P
L
---
A
L
K
F
L
L
G
L
GF
T
Q
L
L
A
----
T
P
Y
L
S
V
D
M
Y
-----
I
S
F
----
V
L
K
L
V
V
A
F
G
I
A
F
E
M
P
I
V
L
Y
V
L
-
Q
K
------------------------------
A
--------------------------
G
V
I
T
P
E
Q
L
A
S
F
R
---------------
K
Y
F
I
V
I
A
--
F
-----
V
I
--------
G
--------
A
I
I
A
-
P
D
V
S
T
Q
V
L
M
A
I
P
--
L
L
L
L
Y
E
I
-----
S
I
F
L
G
K
L
-------------------------------------------------------------------
3
PsiBlast_PDB
85.27
38%
-197
- C7 -
4HTS
-
TATC_AQUAE
A:
[9-236]
-----------------------------
E
H
L
R
E
L
R
Y
R
L
-----
I
I
S
I
I
A
-
F
L
I
G
S
G
I
A
F
Y
F
A
K
Y
V
F
E
I
L
A
A
P
------
I
L
K
S
Y
P
E
-
V
E
L
I
T
L
S
P
T
E
P
L
F
I
----------------
L
I
K
I
S
L
A
V
G
F
I
I
A
S
----------------
P
V
I
L
Y
Q
F
W
R
F
I
E
P
A
L
Y
S
H
E
K
R
A
F
I
P
L
L
L
G
--------
S
I
----
L
L
F
M
L
G
A
L
F
A
Y
F
I
V
L
P
L
---
A
L
K
F
L
L
G
L
GF
T
Q
L
L
A
----
T
P
Y
L
S
V
D
M
Y
-----
I
S
F
----
V
L
K
L
V
V
A
F
G
I
A
F
E
M
P
I
V
L
Y
V
L
-
Q
K
------------------------------
A
--------------------------
G
V
I
T
P
E
Q
L
A
S
F
R
---------------
K
Y
F
I
V
I
A
--
F
-----
V
I
--------
G
--------
A
I
I
A
-
P
D
V
S
T
Q
V
L
M
A
I
P
--
L
L
L
L
Y
E
I
-----
S
I
F
L
G
K
L
A
---
T
R
-------------------------------------------------------------
29
Fugue
65.48
15%
-113
* C5 *
1F88
8
OPSD_BOVIN
A:
[1-348]
----
M
N
G
T
E
G
P
N
FYVPFSN
K
T
G
V
V
R
S
P
F
E
A
P
Q
Y
Y
L
A
E
P
W
-----
Q
F
S
M
L
A
A
Y
M
F
L
L
I
M
-
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
------
Q
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
----------------
M
V
F
G
G
F
T
T
T
L
Y
T
S
L
H
GYFVFG
P
T
G
C
N
L
E
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
--------
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
T
W
V
M
A
L
A
C
AAP
P
L
V
G
W
S
R
Y
--
I
P
E
G
M
----
Q
C
S
C
G
I
D
Y
Y
TPHEE
T
N
N
----
E
S
F
V
I
Y
M
F
V
V
H
F
I
I
P
L
I
V
I
F
F
-
C
Y
------------------------------
G
Q
L
VFTVKEAAASATTQK
A
E
K
E
V
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
---------------
P
Y
A
G
V
A
F
--
Y
-----
I
F
--------
T
H
QGSDFGP
I
F
M
T
I
P
A
F
F
A
K
T
S
A
V
Y
N
--
P
V
I
Y
I
M
M
-----
N
K
Q
F
R
N
C
M
---
V
T
T
L
C
C
G
K
N
P
S
T
T
V
S
K
T
E
T
S
Q
V
A
P
A
--------------------------------------
26
Fugue
60.17
12%
-128
- C4 -
1W5C
9
PSBD_THEEB
D:
[1-350]
----
M
T
I
A
I
G
R
A
-------
P
A
E
R
G
W
F
D
I
L
D
D
W
L
K
R
D
R
F
V
-----
F
V
G
W
S
G
I
L
L
F
P
C
A
Y
-
L
A
L
G
G
W
L
T
G
T
T
F
V
T
SWYTHG
L
A
S
S
Y
L
E
G
C
N
F
L
T
V
A
V
S
T
P
A
N
S
MGHSLLLLWGPEAQGD
F
T
R
W
C
Q
L
G
G
L
W
T
F
I
----------------
A
L
H
G
A
F
G
L
I
G
F
M
L
R
Q
F
E
I
A
R
L
V
G
V
R
P
Y
N
A
--------
I
A
----
F
S
A
P
I
A
V
F
V
S
V
F
L
I
Y
P
L
---
G
Q
S
S
W
F
F
A
--
P
S
F
G
V
A
A
I
F
R
F
L
L
F
F
Q
G
F
-----
H
N
W
----
T
L
N
P
F
H
M
M
G
V
A
G
V
L
G
G
A
L
L
C
A
-
I
H
------------------------------
G
--------------------------
A
T
V
E
N
T
L
F
Q
D
G
E
GASTFRAFNPTQAEE
T
Y
S
M
V
T
A
--
N
R
F
W
S
Q
I
F
--------
G
--------
I
A
F
S
N
K
R
W
L
H
F
F
M
L
F
V
P
--
V
T
G
L
W
M
S
-----
A
I
G
V
V
G
L
A
---
L
N
L
---
R
S
Y
D
F
I
S
Q
E
I
R
A
A
E
D
P
E
F
E
T
F
Y
T
K
N
L
L
L
N
E
G
I
R
A
W
M
APQDQPH
E
N
F
V
F
P
EEVLPRGN
27
Fugue
55.75
15%
-103
- C5 -
1U19
15
OPSD_BOVIN
A:
[4-349]
----
M
N
G
T
E
G
P
N
FYV----
P
F
S
N
K
T
G
V
V
R
S
P
F
E
A
P
Q
Y
Y
L
AE
P
W
Q
F
S
M
L
A
A
Y
M
F
L
L
I
M
L
-
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
------
H
K
K
-
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
----------------
M
V
F
G
G
F
T
T
T
L
Y
T
S
L
H
GYFVFG
P
T
G
C
N
L
E
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
F
G
E
N
H
A
I
----
M
G
V
A
F
T
W
V
M
A
L
A
C
A
A
P
P
---
L
V
G
W
-
S
R
Y
--
I
P
E
G
M
----
Q
C
S
C
G
I
D
Y
Y
TPHEE
T
N
N
----
E
S
F
V
I
Y
M
F
V
V
H
F
I
I
P
L
I
V
I
F
F
-
C
Y
G
Q
L
VFTVKEAAAQQQESA
T
T
Q
K
A
E
K
E
V
T
R
M
V
--------------------------
I
I
M
V
I
A
F
L
I
C
W
L
---------------
P
Y
A
G
V
A
F
--
Y
-----
I
F
T
H
QGSDFG
P
--------
I
F
M
T
I
P
A
F
F
A
K
T
S
A
V
Y
N
--
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
C
---
C
G
K
---
N
P
L
G
D
D
E
A
S
T
T
V
S
K
T
E
T
S
Q
V
APA----------------------------------
12
PsiBlast_PDB
54.72
26%
-158
- C7 -
3VGA
1
AA2AR_HUMAN
A:
[33-130]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
N
S
N
-----
L
Q
N
----
V
T
N
Y
F
V
V
S
L
A
A
A
D
I
A
V
G
V
L
A
I
-
P
F
------------------------------
A
--------------------------
I
T
I
S
T
G
F
C
A
A
C
H
---------------
G
C
L
F
I
A
C
--
F
-----
V
------------------
L
V
L
T
Q
S
S
I
F
S
L
L
A
I
A
I
D
--
R
Y
I
A
I
R
I
-----
P
L
R
Y
N
G
L
V
T
G
T
R
A
K
---
G
--------------------------------------------------------
11
PsiBlast_PDB
54.46
26%
-146
- C7 -
3VG9
4
?
A:
[33-130]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
N
S
N
-----
L
Q
N
----
V
T
N
Y
F
V
V
S
L
A
A
A
D
I
A
V
G
V
L
A
I
-
P
F
------------------------------
A
--------------------------
I
T
I
S
T
G
F
C
A
A
C
H
---------------
G
C
L
F
I
A
C
--
F
-----
V
------------------
L
V
L
T
Q
S
S
I
F
S
L
L
A
I
A
I
D
--
R
Y
I
A
I
R
I
-----
P
L
R
Y
N
G
L
V
T
G
T
R
A
K
---
G
--------------------------------------------------------
23
Fugue
54.44
8%
-152
- C5 -
3QWL
4
TBCD7_HUMAN
A:
[22-293]
G
V
E
E
K
K
S
L
E
I
L
L
-------
K
D
D
R
L
D
T
E
K
L
C
T
F
S
Q
R
F
P
L
P
-----
S
M
Y
R
A
L
V
W
K
V
L
L
G
I
-
L
P
P
H
H
E
S
H
A
K
V
M
M
Y
------
R
K
E
Q
Y
L
D
V
L
H
A
L
K
V
-----
V
R
F
----------------
V
S
D
A
T
P
Q
A
E
V
Y
L
R
M
----------------
Y
Q
L
E
S
G
K
L
P
R
-
S
P
S
F
P
L
E
P
D
D
E
V
F
L
A
I
A
K
--------
A
M
----
E
E
M
V
E
D
S
V
D
C
Y
W
I
T
R
R
F
---
V
N
Q
L
N
T
K
Y
--
R
D
S
L
P
----
Q
L
P
K
A
F
E
Q
Y
-----
L
N
L
E
D
G
R
L
L
T
H
L
R
M
C
S
A
A
P
K
L
P
Y
D
L
W
F
K
R
C
F
------------------------------
A
--------------------------
G
C
L
P
E
S
S
L
Q
R
V
W
---------------
D
K
V
V
S
G
S
CK
I
-----
L
V
--------
F
--------
V
A
V
E
I
L
L
T
F
K
I
K
V
M
A
L
N
S
A
E
K
I
T
K
F
L
-----
E
N
I
P
Q
D
S
S
---
D
A
I
---
V
S
K
A
I
D
L
W
H
K
H
C
G
T
P
V
H
S
---------------------------------------
4
PsiBlast_PDB
53.47
26%
-155
- C7 -
4EIY
12
AA2AR_HUMAN (first)
A:
[58-163]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
N
S
N
-----
L
Q
N
----
V
T
N
Y
F
V
V
S
L
A
A
A
D
I
A
V
G
V
L
A
I
-
P
F
------------------------------
A
--------------------------
I
T
I
S
T
G
F
C
A
A
C
H
---------------
G
C
L
F
I
A
C
--
F
-----
V
------------------
L
V
L
T
Q
S
S
I
F
S
L
L
A
I
A
I
D
--
R
Y
I
A
I
R
I
-----
P
L
R
Y
N
G
L
V
T
G
T
R
A
K
---
G
--------------------------------------------------------
9
PsiBlast_PDB
53.43
26%
-155
- C7 -
3EML
7
ENLYS_BPT4
A:
[48-145]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
N
S
N
-----
L
Q
N
----
V
T
N
Y
F
V
V
S
L
A
A
A
D
I
A
V
G
V
L
A
I
-
P
F
------------------------------
A
--------------------------
I
T
I
S
T
G
F
C
A
A
C
H
---------------
G
C
L
F
I
A
C
--
F
-----
V
------------------
L
V
L
T
Q
S
S
I
F
S
L
L
A
I
A
I
D
--
R
Y
I
A
I
R
I
-----
P
L
R
Y
N
G
L
V
T
G
T
R
A
K
---
G
--------------------------------------------------------
5
PsiBlast_PDB
53.35
26%
-150
- C7 -
2YDO
1
?
A:
[33-133]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
N
S
N
-----
L
Q
N
----
V
T
N
Y
F
V
V
S
A
A
A
A
D
I
L
V
G
V
L
A
I
-
P
F
------------------------------
A
--------------------------
I
A
I
S
T
G
F
C
A
A
C
H
---------------
G
C
L
F
I
A
C
--
F
-----
V
------------------
L
V
L
T
A
S
S
I
F
S
L
L
A
I
A
I
D
--
R
Y
I
A
I
R
I
-----
P
L
R
Y
N
G
L
V
T
G
T
R
A
K
---
G
--------------------------------------------------------
7
PsiBlast_PDB
52.92
26%
-146
- C7 -
4UG2
2
?
A:
[33-135]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
N
S
N
-----
L
Q
N
----
V
T
N
Y
F
V
V
S
A
A
A
A
D
I
L
V
G
V
L
A
I
-
P
F
------------------------------
A
--------------------------
I
A
I
S
T
G
F
C
A
A
C
H
---------------
G
C
L
F
I
A
C
--
F
-----
V
------------------
L
V
L
T
A
S
S
I
F
S
L
L
A
I
A
I
D
--
R
Y
I
A
I
R
I
-----
P
L
R
Y
N
G
L
V
T
G
T
R
A
K
---
G
--------------------------------------------------------
8
PsiBlast_PDB
52.70
26%
-156
- C7 -
4UHR
1
AA2AR_HUMAN
A:
[33-127]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
N
S
N
-----
L
Q
N
----
V
T
N
Y
F
V
V
S
A
A
A
A
D
I
L
V
G
V
L
A
I
-
P
F
------------------------------
A
--------------------------
I
A
I
S
T
G
F
C
A
A
C
H
---------------
G
C
L
F
I
A
C
--
F
-----
V
------------------
L
V
L
T
A
S
S
I
F
S
L
L
A
I
A
I
D
--
R
Y
I
A
I
R
I
-----
P
L
R
Y
N
G
L
V
T
G
T
R
A
K
---
G
--------------------------------------------------------
6
PsiBlast_PDB
52.55
26%
-144
- C7 -
2YDV
4
?
A:
[33-131]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
N
S
N
-----
L
Q
N
----
V
T
N
Y
F
V
V
S
A
A
A
A
D
I
L
V
G
V
L
A
I
-
P
F
------------------------------
A
--------------------------
I
A
I
S
T
G
F
C
A
A
C
H
---------------
G
C
L
F
I
A
C
--
F
-----
V
------------------
L
V
L
T
A
S
S
I
F
S
L
L
A
I
A
I
D
--
R
Y
I
A
I
R
I
-----
P
L
R
Y
N
G
L
V
T
G
T
R
A
K
---
G
--------------------------------------------------------
10
PsiBlast_PDB
51.66
26%
-149
- C7 -
3QAK
1
ENLYS_BPT4
A:
[48-147]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
N
S
N
-----
L
Q
N
----
V
T
N
Y
F
V
V
S
L
A
A
A
D
I
A
V
G
V
L
A
I
-
P
F
------------------------------
A
--------------------------
I
T
I
S
T
G
F
C
A
A
C
H
---------------
G
C
L
F
I
A
C
--
F
-----
V
------------------
L
V
L
T
Q
S
S
I
F
S
L
L
A
I
A
I
D
--
R
Y
I
A
I
R
I
-----
P
L
R
Y
N
G
L
V
T
G
T
R
A
K
---
G
--------------------------------------------------------
14
HHSearch
37.43
30%
396
- C2 -
3UKX
-
?
C:
[6-24]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
R
R
K
R
K
R
E
W
D
D
D
D
D
P
P
K
K
R
--------------------------------------
15
HHSearch
37.02
19%
432
* C6 *
3UKW
1
?
C:
[7-24]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
R
K
R
P
L
E
W
D
E
D
E
E
P
P
R
K
R
--------------------------------------
28
Fugue
35.89
17%
326
- C3 -
3UL0
-
NCBP1_MOUSE
C:
[3-25]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
S
R
---
R
R
H
S
D
E
N
D
G
G
Q
P
H
K
R
R
K
T
S
D
-------------------------------------
25
Fugue
33.92
18%
21
- C7 -
2JWA
-
ERBB2_HUMAN
A:
[41-84]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
C
--------
P
--------
A
E
Q
R
A
S
P
L
T
S
I
I
S
A
V
V
G
--
I
L
L
V
V
V
L
-----
G
V
V
F
G
I
L
I
---
K
R
R
---
Q
Q
K
I
R
K
---------------------------------------------------