@TOME V2.3
(Mar 2018)

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Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Templates Information:
Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : STS_HUMAN: (2018-10-04 )
MPLRKMKIPFLLLFFLWEAESHAASRPNIILVMADDLGIGDPGCYGNKTIRTPNIDRLASGGVKLTQHLAASPLCTPSRAAFMTGRYPVRSGMASWSRTGVFLFTASSGGLPTDEITFAKLLKDQGYSTALIGKWHLGMSCHSKTDFCHHPLHHGFNYFYGISLTNLRDCKPGEGSVFTTGFKRLVFLPLQIVGVTLLTLAALNCLGLLHVPLGVFFSLLFLAALILTLFLGFLHYFRPLNCFMMRNYEIIQQPMSYDNLTQRLTVEAAQFIQRNTETPFLLVLSYLHVHTALFSSKDFAGKSQHGVYGDAVEEMDWSVGQILNLLDELRLANDTLIYFTSDQGAHVEEVSSKGEIHGGSNGIYKGGKANNWEGGIRVPGILRWPRVIQAGQKIDEPTSNMDIFPTVAKLAGAPLPEDRIIDGRDLMPLLEGKSQRSDHEFLFHYCNAYLNAVRWHPQNSTSIWKAFFFTPNFNPVGSNGCFATHVCFCFGSYVTHHDPPLLFDISKDPRERNPLTPASEPRFYEILKVMQEAADRHTQTLPEVPDQFSWNNFLWKPWLQLCCPSTGLSCQCDREKQDKRLSR

Atome Classification :

(20 SA) .........10........20........30........40........50........60........70........80........90........100..---.....110...-------....120.......130.....-------..140...--------..------------..150..--.....160---------------......---..170.--......180.......190.-------------..--....200.......210.......220.......--------230.......240.......250....-...260---.......270.----.----.-...--.280.......290..-...-----------------------..---------------------------------------------------300-------------------------------------------------------------------------------------------------......--..310.......320.......330.......340....---...350..---------------.-------.----------------------.--..360.....--------------..370-----------------------.......380......---.390......--.400.......410.....-.-------.-----420.--......-.430....--.--..440.....--------------.----------------.450---........460.......470..---.....480.......490.-----------------------......500---........510----.......--.--520........530---.......540-----.......550..----.....560----.......570-----.......580.--
(Atome) (Ident) (Tito) (Num) (QMean) (Ligand) (Uniprot) MPLRKMKIPFLLLFFLWEAESHAASRPNIILVMADDLGIGDPGCYGNKTIRTPNIDRLASGGVKLTQHLAASPLCTPSRAAFMTGRYPVRSGMASWSRTGVFLF---TASSGGLPTDE-------ITFAKLLKDQGYSTALIGKWHL-------GMSCHSKT--------DF------------CHHPLHH--GFNYFYG----------------ISLTNL---RDCKPG--EGSVFTTGFKRLVFLPLQIV-------------GV--TLLTLAALNCLGLLHVPLGVFFSLLFLAALILTL--------FLGFLHYFRPLNCFMMRNYEIIQQPMS-YDNLTQ---RLTVEAAQFIQ----R----N-TET--PFLLVLSYLHVHTALF-SSK-----------------------DF---------------------------------------------------AG--------------------------------------------------------------------------------------------------KSQHGV--YGDAVEEMDWSVGQILNLLDELRLANDTLIYFTSDQGAH---VEEVSSKG---------------E-------I----------------------H--GGSNGIYKGG--------------KANNW-----------------------EGGIRVPGILRWPRVI---QAGQKIDEPT--SNMDIFPTVAKLAGAPLPE-D-------R-----II-D--GRDLMP-LLEGKSQR--S--DHEFLFHYCN--------------A----------------YLN----AVRWHPQNSTSIWKAFFFTPNFN---PVGSNGCFATHVCFCFGSY-----------------------VTHHDPPL----LFDISKDPRE-----RNPLTPA--S--EP-RFYEILKVMQE---AADRHTQTLP-----EVPDQFSWNNFL----WKPWLQLC----CPSTGLSCQC-----DREKQDKRLSR--
52 Fugue 92.5598% -90 - C2 - - 1P49 STS_HUMAN A:[2-554] ----------------------AASRPNIILVMADDLGIGDPGCYGNKTIRTPNIDRLASGGVKLTQHLA-ASPLTPSRAAFMTGRYPVRSGMASWSRTGVFLF---TASSGGLPTDE-------ITFAKLLKDQGYSTALIGKWHL-------GMSCHSKT--------DF------------CHHPLHH--GFNYFYG----------------ISLTNL---RDCKPG--EGSVFTTGFKRLVFLPLQIV-------------GV--TLLTLAALNCLGLLHVPLGVFFSLLFLAALILTL--------FLGFLHYFRPLNCFMMRNYEIIQQPMS-YDNLTQ---RLTVEAAQFIQ----R----N-TET--PFLLVLSYLHVHTALF-SSK-----------------------DF---------------------------------------------------AG--------------------------------------------------------------------------------------------------KSQHGV--YGDAVEEMDWSVGQILNLLDELRLANDTLIYFTSDQGAH---VEEVSSKG---------------E-------I----------------------H--GGSNGIYKGG--------------KANNW-----------------------EGGIRVPGILRWPRVI---QAGQKIDEPT--SNMDIFPTVAKLAGAPLPE-D-------R-----II-D--GRDLMP-LLEGKSQR--S--DHEFLFHYCN--------------A----------------YLN----AVRWHPQNSTSIWKAFFFTPNFN---PVCFA----THVCFCFGSY-----------------------VTHHDPPL----LFDISKDPRE-----RNPLTPA--S--EP-RFYEILKVMQE---AADRHTQTLP-----EVPDQFSWNNFL----WKPWLQLC----CPSTGLSCQC-----DRE----------
1 PsiBlast_PDB 92.2499% -90 - C2 - - 1P49 STS_HUMAN A:[2-554] ----------------------AASRPNIILVMADDLGIGDPGCYGNKTIRTPNIDRLASGGVKLTQHLAASPL-TPSRAAFMTGRYPVRSGMASWSRTGVFLF---TASSGGLPTDE-------ITFAKLLKDQGYSTALIGKWHL-------GMSCHSKT--------DF------------CHHPLHH--GFNYFYG----------------ISLTNL---RDCKPG--EGSVFTTGFKRLVFLPLQIV-------------GV--TLLTLAALNCLGLLHVPLGVFFSLLFLAALILTL--------FLGFLHYFRPLNCFMMRNYEIIQQPMS-YDNLTQ---RLTVEAAQFIQ----R----N-TET--PFLLVLSYLHVHTALF-SSK-----------------------DF---------------------------------------------------AG--------------------------------------------------------------------------------------------------KSQHGV--YGDAVEEMDWSVGQILNLLDELRLANDTLIYFTSDQGAH---VEEVSSKG---------------E-------I----------------------H--GGSNGIYKGG--------------KANNW-----------------------EGGIRVPGILRWPRVI---QAGQKIDEPT--SNMDIFPTVAKLAGAPLPE-D-------R-----II-D--GRDLMP-LLEGKSQR--S--DHEFLFHYCN--------------A----------------YLN----AVRWHPQNSTSIWKAFFFTPNFN---PV----CFATHVCFCFGSY-----------------------VTHHDPPL----LFDISKDPRE-----RNPLTPA--S--EP-RFYEILKVMQE---AADRHTQTLP-----EVPDQFSWNNFL----WKPWLQLC----CPSTGLSCQC-----DRE----------
21 HHSearch 83.5495% -22 - C2 - - 1P49 STS_HUMAN A:[2-554] ----------------------AASRPNIILVMADDLGIGDPGCYGNKTIRTPNIDRLASGGVKLTQHLAASPL-TPSRAAFMTGRYPVRSGMASWSRTGVFLF---TASSGGLPTDE-------ITFAKLLKDQGYSTALIGKWHL-------GMSCHSKT--------DF------------CHHPLHH--GFNYFYG----------------ISLTNL---RDCKPG--EGSVFTTGFKRLVFLPLQIVGVTLLTLAALNCLGLLHVPLGVFFSLLFLAA--LI---LTL----FLGFLH--------YFR------PLNCFMMRNYEIIQQPMS-YDNLTQ---RLTVEAAQFIQ----R----N-TET--PFLLVLSYLHVHTALF-SSK-----------------------DF---------------------------------------------------AG--------------------------------------------------------------------------------------------------KSQHGV--YGDAVEEMDWSVGQILNLLDELRLANDTLIYFTSDQGAH---VEEVSSKG---------------E-------I----------------------H--GGSNGIYKGG--------------KANNW-----------------------EGGIRVPGILRWPRVI---QAGQKIDEPT--SNMDIFPTVAKLAGAPLPE-D-------R-----II-D--GRDLMP-LLEGKSQR--S--DHEFLFHYCN--------------A----------------YLN----AVRWHPQNSTSIWKAFFFTPNFN---PV----CFATHVCFCFGSY-----------------------VTHHDPPL----LFDISKDPRE-----RNPLTPA--S--EP-RFYEILKVMQE---AADRHTQTLP-----EVPDQFSWNNFL----WKPWLQLC----CPSTGLSCQC-----DRE----------
54 Fugue 58.0136% -15 - C2 - - 1E3C - ARSA_HUMAN P:[1-485] ------------------------RPPNIVLIFADDLGYGDLGCYGHPSSTTPNLDQLAAGGLRFTDFYVPVSLSTPSRAALLTGRLPVRMGMYPGV-----LV---PSSRGGLPLEE-------VTVAEVLAARGYLTGMAGKWHL-------GVGPEGA------------------------FLPPHQ--GFHRFLG----------------IPYSH----DQGPCQ--NLTCFPPA------------------------------------------------------------TPC--------DGGCDQGLVPIP--LLANLSVEAQPPW-LPGLEA---RYMAFAHDLMA----D----A-QREDRPFFLYYASHHTHYPQF-SGQ-----------------------SF---------------------------------------------------AE--------------------------------------------------------------------------------------------------RSGRGP--FGDSLMELDAAVGTLMTAIGDLGLLEETLVIFTADNGPE---TMR--------------------M-------S----------------------R--GGCSGLLRCG--------------KGTTY-----------------------EGGVREPALAFWPGHI---APGVT-HELA--SSLDLLPTLAALAGAPLPN-V-------T-----L--D--GFDLSP-LLLGTGKS--P--RQSLFFYPSY--------------P----------------DEVRGVFAVRTGK------YKAHFFTQGSA---HSDTTADPACHA----SSS-----------------------LTAHEPPL----LYDLSKDPGE-----NYNL-LG--A--TP-EVLQALKQLQL---LKAQLDAAVT-----FGPSQVARGE-------DPALQICCHPGCTPRPACCHC-----P------------
35 HHSearch 56.0228% -16 - C2 - - 5G2V ? A:[27-511] ------------------------KRPNIIFMMTDDHTTQAMSCYGGNLIQTPNMDRIANEGIRFDNCYAVNALSGPSRACILTGKFSHENGFTDNAS--------------TFNGDQ-------QTFPKLLQQAGYQTAMIGKWHL-------ISE--------------------------------PQ--GFDHWSI----------------LSGQHE---Q--------G-DYY---DP----------------------------------------------------------DF--------WED--------------GKH----IVE-KGYATD---IITDKAINFLE----NR---D-KNK--PFCMMYHQKAPHRNWM-PAP-----------------------RH---------------------------------------------------LGIFNNTIFPEPANLFDDYEGRGKAAREQDMSIEHTLTNDWDLKLLTREEMLKDTTNRLYSVYKRMPSEVQDKWDSAYAQRIAEYRKGDLKGKALISWKYQQYMRD--YLATVLAVDENIGRLLNYLEKIGELDNTIIVYTSDQGFF---LGEHGW-----------------------------------------------------------FD--------------KRFMY-----------------------EECQRMPLIIRYPKAI---KAGSTSSAIS--MNVDFAPTFLDFAGVEVPS---------------DI-Q--GASLKP-VLENEGKTPAD--WRKAAYYHYYEYPAEHSV------K----------------RHY----GI------RTQDFKLIHFY--------------------------------------------------NDIDEWE----MYDMKADPRE-----MNNIFGK--AEYAK-KQKELMQLLEE---TQKQY------------------------------------------------------------------
43 HHSearch 51.8124% -4 - C2 - - 4CYS ARS_PSEAE A:[3-525] ------------------------KRPNFLVIVADDLGFSDIGAFGG-EIATPNLDALAIAGLRLTDFHT-ASA-SPTRSMLLTGTDHHIAGIGTVAEALTPELEGKPGYEGHLNERV-------VALPELLREAGYQTLMAGKWHL-------GLKPE--------------------------QTPHAR--GFERSFS----------------LLPGAA---NH-Y-G------FEPPYDEST---------------------------P----RILKG-----------------TPAL--------YVEDER-------------YLDT-LPE-GFYSSD---AFGDKLLQYLK----ER---D-QSR--PFFAYLPFSAPHWPLQ-APR-----------------------EI---------------------------------------------------VEKYRGRYDAGPEALRQERLARLKELGLVEADVEAHPVLALTREWEALEDEERAKS--------------------------------------------ARAMEV--YAAMVERMDWNIGRVVDYLRRQGELDNTFVLFMSDNGAE---GALLEAFPKFG------------PDLLDFLDRHYDNSLENIGSANSYVWYGPRWA--QAATAPSRLY--------------KAFTT-----------------------QGGIRVPALVRYPRLS---RQGAISHAFA--TVMDVTPTLLDLAGVRHPG-KRWRGREIA-----EP-R--GRSWLG-WLSGETEA--A--HDENTVTGWGL-------------F----------------GMR----AI------RQGDWKAVYLPA------------------------------------------------PVGPATWQ----LYDLARDPGE-----IHDLADS--Q--PG-KLAELIEHWKR---YVSDTG-----------------------------------------------------------------
16 PsiBlast_PDB 51.2023% 2 - C2 - - 5AJ9 ARS_PSEAE A:[3-515] ------------------------KRPNFLVIVADDLGFSDIGAFGGE-IATPNLDALAIAGLRLTDFHTAS-A-SPTRSMLLTGTDHHIAGLGTVAEA----L---TPELEGKPGYEGHLNERVVALPELLREAGYQTLMAGKWHL-------GLKPEQT--------------------------PHAR--GFERSFS----------------L-----------LPG--AANHYGFEPPYDESTPRILK-------------GT--PALYVEDERYLDTL--PEGFYSSDAFGDKLLQYLKERDQSRPFFAYLPFSAP-HWPLQAPREIVEKYRGRYDAGPE---ALRQERLARLK----ELGLVE-ADV--EAHPVLALTREWEALE-DEE-----------------------RA---------------------------------------------------KS--------------------------------------------------------------------------------------------------ARAMEV--YAAMVERMDWNIGRVVDYLRRQGELDNTFVLFMSDNGAEGALLEAFPKFGPDLLDFLDRHYDNSLE-------N----------------------I--GSANSYVWYGPRWAQAATAPSRLYKAFTT-----------------------QGGIRVPALVRYPRLS---RQGAISHAFA--TVMDVTPTLLDLAGVRHPG-K-------RWRGREIA-EPRGRSWLG-WLSGETEA--A------------------------------------------------------HDENTVTGWGLF----GMR---AIRQGDWKAVYLPAPVGPA-----------------------TWQ---------LYDLARDPGE-----IHDLADS--Q--PG-KLAELIE------------------------------------------------------------------------------
40 HHSearch 51.0327% -18 - C2 - - 4UG4 - BETC_RHIME G:[7-449] ------------------------GKPNILIIMVDQLNGKLFPDGPADFLHAPNLKALAKRSARFHNNYTSSPLCAPARASFMAGQLPSRTRVYDNAA--------------EYQSSI-------PTYAHHLRRAGYYTALSGKMHF-------VGPD------------------------------QLH--GFEERLT----------------TDIYPA---DFGWT-----PDYRK----------------------------------------------PG-----------ERIDW--------WYHNLG-------SVTGAG-VAEIT-N-QMEYDDEVAFLANQKLYQLSRENDD----E-SRR--PWCLTVSFTHPHDPYV-ARR-----------------------KF---------------------------------------------------WDLYEDCEHLTPEVGAIPLDEQDPHSQRIMLSCDYQNFDVTEENV-------------------------------------------------------RRSRRA--YFANISYLDEKVGELIDTLTRTRMLDDTLILFCSDHGDM---LGERGL-----------------------------------------------------------WF--------------KMNFF-----------------------EGSARVPLMIAGPGIA----PG-LHLTPT--SNLDVTPTLADLAGISLEEVR-------P-----WT-D--GVSLVP-MVNGVER------TEPVLMEYAAEASY----------A----------------PLV----AI------REGKWKYVYC----------------------------------------------------ALDPEQ----LFDLEADPLE-----LTNLAEN--P--RGPVDQATLTAFRD---MRA--------------------------------------------------------------------
42 HHSearch 50.9423% -3 - C2 - - 2QZU - ? A:[20-475] ------------------QAQEKQPTPNLVFIMADQYRGDAIGCIGKEPVKTPHLDKLASEGINFTNAISSYPVSSPARGMLMTGMYPIGSKVTGNCNSETA------PYGVELSQNA-------RCWSDVLKDQGYNMGYIGKWHL-------DAPYKPYV--------DTYNNRGKVAWNEWCPPERRH--GFDHWIA----------------YGTYDY------HL-------------KP---------------------------------------------------------MY--------WNTT----------APRD----SFYYV-NQWGPE---YEASKAIEYIN----GQK--D-QKQ--PFALVVSMNPPHTGYELVPD-----------------------RY---------------------------------------------------KEIYKDLDVEALCKGRPDIPAKGTEMGDYF----------------------------------------------------------------------RNNIRN--YYACITGVDENVGRIIEALKQNNLFDNTIVVFTSDHGIC---MGAHEN-----------------------------------------------------------AG--------------KDIFY-----------------------EESMRIPMILSWPDQI---KPRKSDPLMI--AFADLYPTLLSMMGFSKEI-P-------E-----TV-Q--TFDLSNEVLTGKNKKD-L--VQPYYFVKFD--------------NHAT-------------GYR----GL------RTDRYTYAVHAT------------------------------------------------DGKIDNVI----LFDRTNDPHE-----MNNIASQ--Q--LK-LTHTFNRQLKT---WLEKTNDP---------------------------------------------------------------
41 HHSearch 50.9327% -21 - C2 - - 4UG4 - BETC_RHIME A:[4-449] ---------------------VTTGKPNILIIMVDQLNGKLFPDGPADFLHAPNLKALAKRSARFHNNYTSSPLCAPARASFMAGQLPSRTRVYDNAA--------------EYQSSI-------PTYAHHLRRAGYYTALSGKMHF-------VGPD------------------------------QLH--GFEERLT----------------TDIYPA---DFGWT-----PDYRK----------------------------------------------PG-----------ERIDW--------WYHNLG-------SVTGAG-VAEIT-N-QMEYDDEVAFLANQKLYQLSRENDD----E-SRR--PWCLTVSFTHPHDPYV-ARR-----------------------KF---------------------------------------------------WDLYEDCEHLTPEVGAIPLDEQDPHSQRIMLSCDYQNFDVTEENV-------------------------------------------------------RRSRRA--YFANISYLDEKVGELIDTLTRTRMLDDTLILFCSDHGDM---LGERGL-----------------------------------------------------------WF--------------KMNFF-----------------------EGSARVPLMIAGPGIA----PG-LHLTPT--SNLDVTPTLADLAGISLEEVR-------P-----WT-D--GVSLVP-MVNGVER------TEPVLMEYAAEASY----------A----------------PLV----AI------REGKWKYVYC----------------------------------------------------ALDPEQ----LFDLEADPLE-----LTNLAEN--P--RGPVDQATLTAFRD---MRA--------------------------------------------------------------------
30 HHSearch 50.8230% -19 - C2 - - 1FSU - ARSB_HUMAN A:[1-468] -----------------------SRPPHLVFLLADDLGWNDVGFHGS-RIRTPHLDALAAGGVLLDNYYTQ-PL-TPSRSQLLTGRYQIRTGLQHQIIWPC--------QPSCVPLDE-------KLLPQLLKEAGYTTHMVGKWHL-------GMYRKE-------------------------CLPTRR--GFDTYFG----------------YLLGS----EDYYSH--ER-CTL---IDAL-----------------------------------N-------------------VTR--------CA--------L---DFRDGEEVATGYK-NMYSTN---IFTKRAIALIT----N----HPPEK--PLFLYLALQSVHEPLQ-VPE-----------------------EY---------------------------------------------------LKPYDFIQ--------------------------------------------------------------------------------------------DKNRHH--YAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQ---TLAGGN------------------------------------------------------NWPLRGR--------------KWSLW-----------------------EGGVRGVGFVASPLLK---QKGVKNRELI--HISDWLPTLVKLARGHTNG-T-------K-----PL-D--GFDVWK-TISEGSPS-----PRIELLHNIDPNFVDSSPCSAFNTS----------------VHA----AI------RHGNWKLLTGYPGCGYWFPPPSQYNVSE-----IPSS-----------------------DPPTKTLW----LFDIDRDPEE-----RHDLSRE--Y--PH-IVTKLLSRLQF---YHKHS------------------------------------------------------------------
2 PsiBlast_PDB 50.8230% -2 - C2 - - 3ED4 ? A:[27-406] -------------------------QPNLVIIMADDLGYGDLATYGHQIVKTPNIDRLAQEGVKFTDYYAPAPLSSPSRAGLLTGRMPFRTGIRSWIPSGKDV---------ALGRNE-------LTIANLLKAQGYDTAMMGKLHL-----------NAGG--------DR------------TDQPQAQDMGFDY--------------------SLAN-----------------TAGF---------VT-------------DA--TLDNAKERPRYGMVYP---------------------------TGWLRNGQP-------------TPRA-DKMSGE---YVSSEVVNWLD----N----K-KDSK-PFFLYVAFTEVHSPLA-SPKKYLDMYSQYMSAYQKQHPDLFYGDW---------------------------------------------------AD--------------------------------------------------------------------------------------------------KPWRGVGEYYANISYLDAQVGKVLDKIKAMGEEDNTIVIFTSDNGPV---TREARKVY---------------E-------L----------------------NLAGETDGL-RGR--------------KDNLW-----------------------EGGIRVPAIIKYGKHL---PQGMVSDTPV--YGLDWMPTLAKMMNFKLPT-D-------R-----TF-D--GESLVP-VLEQKALK--R--EKPLIF---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17 PsiBlast_PDB 50.7623% -0 - C2 - - 4CYS ARS_PSEAE A:[3-515] ------------------------KRPNFLVIVADDLGFSDIGAFGGE-IATPNLDALAIAGLRLTDFHTAS-A-SPTRSMLLTGTDHHIAGIGTVAEA----L---TPELEGKPGYEGHLNERVVALPELLREAGYQTLMAGKWHL-------GLKPEQT--------------------------PHAR--GFERSFS----------------L-----------LPG--AANHYGFEPPYDESTPRILK-------------GT--PALYVEDERYLDTL--PEGFYSSDAFGDKLLQYLKERDQSRPFFAYLPFSAP-HWPLQAPREIVEKYRGRYDAGPE---ALRQERLARLK----ELGLVE-ADV--EAHPVLALTREWEALE-DEE-----------------------RA---------------------------------------------------KS--------------------------------------------------------------------------------------------------ARAMEV--YAAMVERMDWNIGRVVDYLRRQGELDNTFVLFMSDNGAEGALLEAFPKFGPDLLDFLDRHYDNSLE-------N----------------------I--GSANSYVWYGPRWAQAATAPSRLYKAFTT-----------------------QGGIRVPALVRYPRLS---RQGAISHAFA--TVMDVTPTLLDLAGVRHPG-K-------RWRGREIA-EPRGRSWLG-WLSGETEA--A------------------------------------------------------HDENTVTGWGLF----GMR---AIRQGDWKAVYLPAPVGPA-----------------------TWQ---------LYDLARDPGE-----IHDLADS--Q--PG-KLAELIE------------------------------------------------------------------------------
29 HHSearch 50.7421% -15 - C2 - - 5G2U ? A:[22-450] ------------------------EKPNFLIIQCDHLTQRVVGAYGQTQGCTLPIDEVASRGVIFSNAYVGCPLSQPSRAALWSGMMPHQTNVRSNSSEP---------VNTRLPENV-------PTLGSLFSESGYEAVHFGKTHD-------MGS--------------------------------LR--GFKHKEP----------------VAKP-F-------T-------------DP----------------------------------------------------------E--------FPV----------------------NN-DSFLDV---GTCEDAVAYLS----N----P---E--PFICIADFQNPHNICG-FIG-----------------------ENAGVHTDRPISGPLPELPDNFDVEDWSNIPTPVQYICCSHRRMTQAAHWNEENY--------------------------------------------------------------------------------------------------RHYIAA--FQHYTKMVSKQVDSVLKALYSTPAGRNTIVVIMADHGDG---MASHRMV----------------------------------------------------------TK--------------HISFY-----------------------DEMTNVPFIFAGPGIK---QQKKPVDHLLTQPTLDLLPTLCDLAGIAVPA---------------EK-A--GISLAP-TLRGEKQK--K--SHPYVVSEWH--------------SEYEYVTT---------PGR----MV------RGPRYKYTHYL---------------------------------------------------EGNGEE----LYDMKKDPGE-----RKNLAKD--PKYSK-ILAEHRALLDD---YIT--------------------------------------------------------------------
55 Fugue 50.6726% -15 - C2 - - 4UG4 - BETC_RHIME A:[1-515] ------------------GDPVTTGKPNILIIMVDQLNGKLFPDGPADFLHAPNLKALAKRSARFHNNYTSSPLCAPARASFMAGQLPSRTRVYD--------------NAAEYQSSI-------PTYAHHLRRAGYYTALSGKMHFVGPDQLHGFEERLTT--------DI--------------YPADF--GWTPDYR----------------KPGERI---DWWYHN--LGSVTGAGVAEITNQMEYDD-------------EV--AFLANQKLYQLSRENDDESRR---------PWCL--------TVSFTHPHDP--------YVARRKFWD-LYEDCE---HLTPEVGA-IP----L----D-EQD--PHSQRIMLSCDYQNFD-VTE-----------------------EN---------------------------------------------------VR--------------------------------------------------------------------------------------------------RSRRAY--FAN-ISYLDEKVGELIDTLTRTRMLDDTLILFCSDHGDM---L---------------------------------------------------------GERGLWF----------------KMNFF-----------------------EGSARVPLMIAGPG-I---APGLHLT-PT--SNLDVTPTLADLAGISLEE-V-------R-----PWTD--GVSLVP-MVNGVERT--EPVLMEYAAEASY--------------A----------------PLV----AIREGK------WKYVYCAL----------------------------------------------------DPEQ----LFDLEADPLELTNLAENPRGPV--D--QA-TLTAFRDMRAAHWDMEAFDAAVRE-----SQARRWVVYEALRNGAYYPWDHQP----LQKASERYMRNHMNLDTLEESKRYPRGE
28 HHSearch 50.6422% -16 - C2 - - 3B5Q ? B:[15-445] ------------------------EKPNFLIIQCDHLTQRVVGAYGQTQGCTLPIDEVASRGVIFSNAYVGCPLSQPSRAALWSGMMPHQTNVRSNSSEP---------VNTRLPENV-------PTLGSLFSESGYEAVHFGKTHD-------MGS--------------------------------LR--GFKHKEP----------------VAKP--------FTD-------------P----------------------------------------------------------E--------FPV----------------------NN-DSFLDV---GTCEDAVAYLS----N----P-PKE--PFICIADFQNPHNICG-FIG-----------------------ENAGVHTDRPISGPLPELPDNFDVEDWSNIPTPVQYICCSHRRMTQAAHWNEENY--------------------------------------------------------------------------------------------------RHYIAA--FQHYTKMVSKQVDSVLKALYSTPAGRNTIVVIMADHGDG---MASHRMV----------------------------------------------------------TK--------------HISFY-----------------------DEMTNVPFIFAGPGIK---QQKKPVDHLLTQPTLDLLPTLCDLAGIAVPA---------------EK-A--GISLAP-TLRGEKQK--K--SHPYVVSEWH--------------SEYEYVTT---------PGR----MV------RGPRYKYTHYL---------------------------------------------------EGNGEE----LYDMKKDPGE-----RKNLAKD--PKYSK-ILAEHRALLDD---YITRS------------------------------------------------------------------
12 PsiBlast_PDB 50.4324% -13 - C2 - - 1FSU - ARSB_HUMAN A:[4-492] --------------------------PHLVFLLADDLGWNDVGFHGSR-IRTPHLDALAAGGVLLDNYYT-QPL-TPSRSQLLTGRYQIRTGLQH-----QIIW---PCQPSCVPLDE-------KLLPQLLKEAGYTTHMVGKWHL-------GM--YRKE--------CL---------------PTRR--GFDTYFGYLLGSEDYYSHERCTLIDALNV---TRCALDFRDGEEVATGYKNM-------Y-------------ST--NIFTKRAI-ALITNHPPEKPLFLYLALQSV------------------------------HEPLQVPEE-Y-----------LKPYDFIQ-----------------------------------------------------------------------------------------------------------------D--------------------------------------------------------------------------------------------------KNRHH---YAGMVSLMDEAVGNVTAALKSSGLWNNTVFIFSTDNGGQ---T------------------------------L----------------------A--GGNNWPLRGR--------------KWSLW-----------------------EGGVRGVGFVASPLLK---QKGVKNRELI--HISDWLPTLVKLARGHTNG-T-------K-----PL-D--GFDVWK-TISEGSPS--P--RIELLHNIDP--------------N----------------FVD----SSPC------------------S---AFNT----SVHAAIRHGNWKLLTGYPGCGYWFPPPSQYNVSEIPSSDPPTKTLWLFDIDRDPEE-----RHDL-----S--RE-YPHIVTKLLSR---LQFYHKHSVPVYFPAQDPRCDPKATGV----WGPWM-----------------------------------
13 PsiBlast_PDB 49.9823% 9 - C2 - - 4CXU ARS_PSEAE A:[3-515] ------------------------KRPNFLVIVADDLGFSDIGTFGGE-IATPNLDALAIAGLRLTDFHTAS-A-SPTRSMLLTGTDHHIAGIGTMAEA----L-----------GYEGHLNERVVALPELLREAGYQTLMAGKWHL-------GLKPEQT--------------------------PHAR--GFERSFA----------------L-----------LPG--AANHYGFEPPYDESTPRILK-------------GT--PALYVEDERYLDTL--PEGFYSSDAFGDKLLQYLKERDQSRPFFAYLPFSAP-HWPLQAPREIVEKYRGRYDAGPE---ALRQERLARLK----ELGLVE-ADV--EAHPVLALTREWEALE-DEE-----------------------RA---------------------------------------------------KS--------------------------------------------------------------------------------------------------ARAMEV--YAAMVERMDWNIGRVVDYLRRQGELDNTFVLFMSDNGAEGALLEAFPKFGPDLLDFL--------D-------R----------------------H---YDNSLENIG--------------RANSYVWYGPRWAQAATAPSRLYKAFTTQGGIRVPALVRYPRLS---RQGAISHAFA--TVMDVTPTLLDLAGVRHPG-K-------RWRGREIA-EPRGRSWLG-WLSGETEA--A------------------------------------------------------HDENTVTGWGLF----GMR---AIRQGDWKAVYLPAPVGPA-----------------------TWQ---------LYDLARDPGE-----IHDLADS--Q--PG-KLAELIE------------------------------------------------------------------------------
18 PsiBlast_PDB 49.8723% 1 - C2 - - 4CXK - ARS_PSEAE A:[3-515] ------------------------KRPNFLVIVADDLGFSDIGAFGGE-IATPNLDALAIAGLRLTDFHTTS-A-SPTRSMLLTGTDHHIAGLGTVAEA----L---TPELEGKPGYEGHLNERVVALPELLREAGYQTLMAGKWHL-------GLKPEQT--------------------------PHAR--GFERSFS----------------L-----------LPG--AANHYGFEPPYDESTPRILK-------------GT--PALYVEDERYLDTL--PEGFYSSDAFGDKLLQYLKERDQSRPFFAYLPFSAP-HWPLQAPREIVEKYRGRYDAGPE---ALRQERLARLK----ELGLVE-ADV--EAHPVLALTREWEALE-DEE-----------------------RA---------------------------------------------------KS--------------------------------------------------------------------------------------------------ARAMEV--YAAMVERMDWNIGRVVDYLRRQGELDNTFVLFMSDNGAEGALLEAFPKFGPDLLDFLDRHYDNSLE-------N----------------------I--GSANSYVWYGPRWAQAATAPSRLYKAFTT-----------------------QGGIRVPALVRYPRLS---RQGAISHAFA--TVMDVTPTLLDLAGVRHPG-K-------RWRGREIA-EPRGRSWLG-WLSGETEA--A------------------------------------------------------HDENTVTGWGLF----GMR---AIRQGDWKAVYLPAPVGPA-----------------------TWQ---------LYDLARDPGE-----IHDLADS--Q--PG-KLAELIE------------------------------------------------------------------------------
27 HHSearch 49.4924% -12 - C2 - - 4UPL - ? A:[15-515] -----------------------TAVMNILFIMFDQLRWDYLSCYGHKTLNTPHIDRLAAKGVRFDRAYIQSPICGSSRMSTYTGRYVHSHGASWNGI--------------PLKVGE-------MTMGDHLRAAGMGCWLVGKTHM-------RADEEGMARLGLEPDSLI------------GARVAEC--GFDVFER----------------DDGMLPEGPDGYYDP--DGAKEYNKFLRAK--------------------GY--E-SDNPWHDFAN-SGLDD--------E-GNVQSG--------WFLKNA---------TRPAN----IAE-EDSETP---YLTSRAMEFIE----Q------QTG--PWCCHLSYIKPHWPYI-VPE-----------------------PY---------------------------------------------------ASMFGPEHVQDVVRSDSERQNAHPLFKAFMDTKVGEAFSRQEVR--------------------------------------------------------DAVIPA--YMGLIKQADDQMGRLFKWLEDTGRMQDTMIVLTSDHGDF---LGDHW-----------------------------------------------------------MGE--------------KTFFH-----------------------DASTRVPLIIYDPRPEADATRGSVCDALV--ESIDLAPTFVEAAGGKPAM---------H-----IL-E--GESLIP-ILHGARDH--T--LRDHVICEYD--------------FSASPIAHLNDISVRQAVMF----MV------ADKNWKLIHFE---------------------------------------------------ADPRPM----LFDLKNDPQE-----LVDLGGDPAH--AD-VIAGMYDKLFR---WTRRQS-----------------------------------------------------------------