@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VL24: (2017-10-30 )
MTKKGSFMPASTSQYYTRTAQILHWVMAIIFITAWVIGFYSGNFLSYDVDGSFKGDVITLHKNIATTIIFLVVIRLFWRYTHPAPQLPDTMSPTMKTLAHIGHLLLYVILVALPVTGCLFSWSAGHPAPVLYLFEIPRLVQDNPELLAIVKPLHIYISWFAGFLIVGHVLAALKHHFVDKDNVLNSMTKQPK
Atome Classification :
(20 SA)
-----------------------------------------------------------------------------------------------------------------------------------------------.........10-........---------------20......------------..30........40-.------...--.---.----.-----------.--50....-------------....60...------------------.....70-.-----........80---------...--......----------------90.--..----...---..100-------------------........110...--..-------------------.-.120......------.--130-.-.......-----------140---------.-----------.....-------...150..-.....----160-........--170.........180----...-......190..----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
-----------------------------------------------------------------------------------------------------------------------------------------------MTKKGSFMPAS-T
S
Q
Y
Y
T
R
T
---------------
A
Q
I
L
H
W
V
M
------------
A
I
I
F
I
T
A
W
V
I
G
FYS-G------
N
F
L
--
S
---
Y
----D-----------V--DGSFKG-------------
D
V
I
T
L
H
K
N
I
------------------
A
T
T
I
I
F
--
L
-----
V
V
I
R
L
F
W
R
Y----------THP--APQLPD----------------TM
S
--
P
T
----
M
K
T
---
L
A
H
I
--------------------
G
H
L
L
L
Y
V
I
L
V
A
L
PV--TG-------------------
C
-
L
FSWSAGHP
A
------
P
--
V
-
L
-
Y
-
L
F
EI
P
R
L
-----------V-----------Q-----------DNP
E
L
-------
L
A
I
V
K
P
L
H
-
I
Y
I
S
W
----
F
A
--
G
F
L
I
V
G
H
V
--
L
--
A
A
L
K
H
HFV
D
K
------
D
N
V
-
L
N
S
MTKQ--PK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
62.12
20%
-150
- C7 -
-
4H13
12
CYB6_MASLA
A:
[39-207]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
T
------------
L
T
C
F
L
I
Q
F
A
T
G
F
A
M
-
T
------
F
Y
Y
K-
P
---
T
----
V
TE
A
Y
A
S
V
Q
Y
I
M
N
--
E
V
S
F
G
W
-------------
L
I
R
S
I
H
R
W
S
------------------
A
S
M
M
V
L
--
M
-----
M
I
L
H
V
F
R
V
Y
----------
L
T
G
--
G
F
K
K
P
R
----------------
E
----------------
L
T
W
I
--------------------
S
G
V
I
L
A
V
I
T
V
S
F
G
V
--
T
G
-------------------
Y
-
S
L
P
W
D
Q
V
G
Y
W
A
V
K
I
V
S
G
--
V
-
P
-
E
---
A
I
P
V
V
G
V
L
I
S
D
L
L
R
GG
S
-----------
S
-----------
V
G
Q
A
T
-------
L
T
R
Y
Y
S
A
H
T
F
V
L
P
W
----
L
I
--
A
V
F
M
L
L
H
F
--
L
--
M
I
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
59.94
18%
-142
- C7 -
-
4OGQ
9
CYB6_NOSS1
A:
[39-207]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
T
------------
L
V
C
F
L
I
Q
F
A
T
G
F
A
M
-
T
------
F
Y
Y
K-
P
---
T
----
V
AE
A
Y
S
S
V
Q
Y
I
M
N
--
E
V
N
F
G
W
-------------
L
I
R
S
I
H
R
W
S
------------------
A
S
M
M
V
L
--
M
-----
M
I
L
H
V
F
R
V
Y
----------
L
T
G
--
G
F
K
K
P
R
----------------
E
-
L
--
T
W
----
V
-----------------------------
S
G
V
I
L
A
V
I
T
V
S
F
G
V
--
T
G
-------------------
Y
-
S
L
P
W
D
Q
V
G
Y
W
A
V
K
I
V
S
G
--
V
-
P
-
E
---
A
I
P
V
V
-----------
G
V
L
I
S
D
L
L
R
GGS
S
-----------
V
G
Q
A
T
-------
L
T
R
Y
Y
S
A
H
T
F
V
L
P
W
----
L
I
--
A
V
F
M
L
F
H
F
--
L
--
M
I
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
Fugue
57.54
14%
-167
- C7 -
-
4GD3
-
CYBH_ECOLI
A:
[8-210]
--------------------------------------------------------------------------------------------------------------------------------------------------------
V
V
-
S
H
Y
V
F
E
A
P
---------------
V
R
I
W
H
W
L
T
------------
V
L
C
M
A
V
L
M
V
T
G
Y
F
I
-
G
------
K
P
L
--
P
---
S
V
S
G
E
A
-----------
T
--
Y
L
F
Y
M
G
-------------
Y
I
R
L
I
H
F
S
A
------------------
G
M
V
F
T
V
--
V
-----
L
L
M
R
I
Y
W
A
F
----------
V
G
N
--
R
Y
S
R
Q
G
----------------
V
W
Y
--
E
I
R
W
Y
L
F
L
P
---
I
A
Q
A
--------------------
A
M
F
G
Y
F
L
M
S
V
F
M
I
I
--
T
G
-------------------
F
-
A
L
Y
S
E
H
S
Q
Y
A
------
I
--
F
-
A
-
P
-
F
R
Y
V
V
E
F
-----------
F
-----------
Y
-----------
W
T
G
G
N
-------
S
M
D
I
H
S
W
H
-
R
L
G
M
W
----
L
I
--
G
A
F
V
I
G
H
V
--
Y
--
M
A
L
R
E
D
I
M
S
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
HHSearch
57.54
18%
-198
- C7 -
-
2QJK
-
CYB_RHOSH
A:
[47-217]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
V
L
------------
A
F
C
L
V
L
Q
I
V
T
G
I
V
L
-
A
------
M
H
Y
T-
P
---
H
----
V
DL
A
F
A
S
V
E
H
I
M
R
--
N
V
N
G
G
F
-------------
M
L
R
Y
L
H
A
N
G
------------------
A
S
L
F
F
I
--
A
-----
V
Y
L
H
I
F
R
G
L
----------
Y
Y
G
--
S
Y
K
A
P
-----------------------------
R
E
---
V
T
W
I
--------------------
V
G
M
L
I
Y
L
A
M
M
A
T
A
F
--
M
G
-------------------
Y
-
V
L
P
W
G
Q
M
S
F
W
G
A
----
T
--
V
I
T
-
G
L
F
G
A
I
P
G
I
-----------
G
-----------
H
S
I
Q
T
W
L
L
GGPA
V
D
N
A
T
-------
L
N
R
F
F
S
L
H
-
Y
L
L
P
F
----
V
I
--
A
A
L
V
A
I
H
I
--
W
--
A
F
H
S
T
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
57.32
18%
-194
- C7 -
-
2QJY
-
CYB_RHOSH
G:
[50-219]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
L
------------
A
F
C
L
V
L
Q
I
V
T
G
I
V
L
-
A
------
M
H
Y
T-
P
---
H
----
V
DLAFASVEHIM
R
--
N
V
N
G
G
F
-------------
M
L
R
Y
L
H
A
N
G
------------------
A
S
L
F
F
I
--
A
-----
V
Y
L
H
I
F
R
G
L
----------
Y
Y
G
--
S
Y
K
A
P
R
-----------------------------
E
---
V
T
W
I
--------------------
V
G
M
L
I
Y
L
A
M
M
A
T
A
F
--
M
G
-------------------
Y
-
V
L
P
W
G
Q
M
S
F
W
GA----
T
--
V
I
T
-
G
L
F
G
A
I
P
G
I
-----------
G
-----------
H
SIQTWLLGGPA
V
D
N
A
T
-------
L
N
R
F
F
S
L
H
-
Y
L
L
P
F
----
V
I
--
A
A
L
V
A
I
H
I
--
W
--
A
F
H
S
T
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
56.76
13%
-173
- C7 -
-
1KQF
3
FDNI_ECOLI
C:
[2-188]
------------------------------------------------------------------------------------------------------------------------------------------------------
S
K
S
K
-
M
I
V
R
T
K
F
I
---------------
D
R
A
C
H
W
T
V
------------
V
I
C
F
F
L
V
A
L
S
G
I
S
F
-
F
------
F
P
T
--
L
---
Q
----
W
-----------
L
TQ
T
F
G
T
P
Q
-------------
M
G
R
I
L
H
P
F
F
------------------
G
I
A
I
F
V
--
A
-----
L
M
F
M
F
V
R
F
V
----------
H
H
N
--
I
P
D
K
K
D
I
P
W
L
L
N
I
V
E
V
L
K
GNEH
K
V
A
D
V
G
K
----
Y
N
A
---
G
Q
K
M
--------------------
M
F
W
S
I
M
S
M
I
F
V
L
L
V
--
T
G
-------------------
V
-
I
I
W
R
P
Y
F
--------------
A
-
Q
---
Y
F
P
---------------------------------------
M
Q
V
-------
V
R
Y
S
L
L
I
H
-
A
A
A
G
I
----
I
L
--
I
H
A
I
L
I
H
M
--
Y
--
M
A
F
W
V
-----------
K
G
S
-
I
K
G
M
I
E
G
--
K
V
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
56.00
13%
-172
- C7 -
-
1KQG
4
FDNI_ECOLI
C:
[2-188]
------------------------------------------------------------------------------------------------------------------------------------------------------
S
K
S
K
-
M
I
V
R
T
K
F
I
---------------
D
R
A
C
H
W
T
V
------------
V
I
C
F
F
L
V
A
L
S
G
I
S
F
-
F
------
F
P
T
--
L
---
Q
----
W
-----------
L
TQ
T
F
G
T
P
Q
-------------
M
G
R
I
L
H
P
F
F
------------------
G
I
A
I
F
V
--
A
-----
L
M
F
M
F
V
R
F
V
----------
H
H
N
--
I
P
D
K
K
D
I
P
W
L
L
N
I
V
E
V
L
K
GNEH
K
V
A
D
V
G
K
----
Y
N
A
---
G
Q
K
M
--------------------
M
F
W
S
I
M
S
M
I
F
V
L
L
V
--
T
G
-------------------
V
-
I
I
W
R
P
Y
F
--------------
A
-
Q
---
Y
F
P
---------------------------------------
M
Q
V
-------
V
R
Y
S
L
L
I
H
-
A
A
A
G
I
----
I
L
--
I
H
A
I
L
I
H
M
--
Y
--
M
A
F
W
V
-----------
K
G
S
-
I
K
G
M
I
E
G
--
K
V
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
Fugue
53.08
19%
-54
- C4 -
-
2OH5
3
?
A:
[2-248]
-------------------------------------------------------------------------------------------------------------------------------------------ADVA
G
T
S
N
R
D
F
R
G
R
E
-
Q
R
L
F
N
S
E
Q
---------------
Y
N
Y
N
N
S
L
N
------------
G
--
E
V
S
V
W
V
Y
A
Y
Y
S
-
D
G
S
V
L
V
I
N
K
N
--
S
Q
Y
K
V
----
G
-----------
I
--
S
E
T
F
K
A
L
K
E
Y
R
K
GQHND
S
Y
D
E
Y
E
V
N
Q
S
I
Y
YPNGGDARKFHSNAKPR
A
I
Q
I
I
F
S
P
S
-----
V
N
V
R
T
I
K
M
A
----------
K
G
N
--
A
V
S
V
P
D
EYLQRSHPWE------
A
T
G
--
I
K
----
Y
R
K
---
I
K
R
D
--------------------
G
E
I
V
G
Y
S
H
Y
F
E
L
P
H
EY
N
S
-------------------
I
-
S
L
A
V
S
G
V
H
K
N
------
P
--
S
-
S
-
Y
-
N
V
G
S
A
H
N
-----------
V
-----------
M
-----------
D
V
F
Q
S
-------
C
D
L
--
A
L
R
-
F
C
N
R
Y
----
W
A
--
E
L
E
L
V
N
H
Y
--
I
--
S
P
N
A
Y
P
Y
L
D
I
------
N
N
H
-
S
Y
G
V
A
L
S
--
N
R
Q---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
49.41
13%
-158
- C7 -
-
3CX5
-
CYB_YEAST
N:
[35-204]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
L
------------
G
L
C
L
V
I
Q
I
V
T
G
I
F
M
-
A
------
M
H
Y
S-
S
---
N
----
I
ELAFSSVEHIM
R
--
D
V
H
N
G
Y
-------------
I
L
R
Y
L
H
A
N
G
------------------
A
S
F
F
F
M
--
V
-----
M
F
M
H
M
A
K
G
L
----------
Y
Y
G
--
S
Y
R
S
P
R
-----------------------------
V
---
T
L
W
N
--------------------
V
G
V
I
I
F
I
L
T
I
A
T
A
F
--
L
G
-------------------
Y
-
C
C
V
Y
G
Q
M
S
H
W
GATVIT
N
--
L
-
F
-
S
---
A
I
P
F
V
-----------
G
-----------
N
DIVSWLWGGFS
V
S
N
P
T
-------
I
Q
R
F
F
A
L
H
-
Y
L
V
P
F
----
I
I
--
A
A
M
V
I
M
H
L
--
M
--
A
L
H
I
H
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
HHSearch
47.79
13%
-157
- C7 -
-
3L71
4
CYB_CHICK
C:
[33-203]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
F
G
S
L
L
------------
A
V
C
L
M
T
Q
I
L
T
G
L
L
L
-
A
------
M
H
Y
T-
A
---
D
----
T
SL
A
F
S
S
V
A
H
T
C
R
--
N
V
Q
Y
G
W
-------------
L
I
R
N
L
H
A
N
G
------------------
A
S
F
F
F
I
--
C
-----
I
F
L
H
I
G
R
G
L
----------
Y
Y
G
--
S
Y
L
Y
-------------------------------
K
---
E
T
W
N
--------------------
T
G
V
I
L
L
L
T
L
M
A
T
A
F
--
V
G
-------------------
Y
-
V
L
P
W
G
Q
M
S
F
W
G
A
T
V
I
T
N
--
L
-
F
-
S
---
A
I
P
Y
I
-----------
G
H
T
L
V
E
W
A
W
GGF
S
-----------
V
D
N
P
T
-------
L
T
R
F
F
A
L
H
-
F
L
L
P
F
----
A
I
--
A
G
I
T
I
I
H
L
--
T
--
F
L
H
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
Fugue
47.45
13%
-139
* C5 *
-
1UKX
-
E2AK4_MOUSE
A:
[1-137]
---------------------------------------------------------------------------------------------------------------------------------------------------
G
S
S
G
S
S
G
-
M
E
S
Y
S
Q
R
Q
---------------
D
H
E
L
Q
A
L
E
------------
A
I
----------------------------------------------------
Y
G
S
-------------
D
F
Q
D
L
R
P
D
----------------------------------------------------
A
R
G
--
R
V
R
E
P
P
----------------
E
I
N
--
L
V
----
L
Y
P
---
Q
G
L
A
--------------------
G
E
E
V
Y
V
Q
V
E
L
R
V
K
C
--
P
P
-------------------
T
-
Y
P
D
-----
V
V
------
P
--
E
-
I
-
D
-
L
K
N
A
K
G
L
-----------------------------------
S
N
E
S
V
-------
N
L
L
K
S
H
L
E
-
E
L
A
K
K
----
Q
C
--
G
E
V
M
I
F
E
L
--
A
--
H
H
V
Q
S
F
L
S
E
H
------
N
K
S
-
G
P
S
S
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
46.99
10%
-222
- C7 -
-
1KQF
3
FDNI_ECOLI
C:
[105-175]
-----------------------------------------------------------------------------------------------------------------------------------------------------------
D
V
G
K
Y
N
A
G
---------------
Q
K
M
M
F
W
S
I
------------
M
S
M
I
F
V
L
L
V
T
G
V
I
I
-
W
------
R
P
Y
--
F
---
A
----
Q
Y----------
F
--
P
M
Q
V
V
R
-------------
Y
S
L
L
I
H
A
A
A
------------------
G
I
I
L
I
H
--
A
-----
I
L
I
H
M
Y
M
A
F
----------
W
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
HHSearch
45.80
13%
0
- C- -
-
1KYO
2
CYB_YEAST
C:
[35-204]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
L
------------
G
L
C
L
V
I
Q
I
V
T
G
I
F
M
-
A
------
M
H
Y
S-
S
---
N
----
I
EL
A
F
S
S
V
E
H
I
M
R
--
D
V
H
N
G
Y
-------------
I
L
R
Y
L
H
A
N
G
------------------
A
S
F
F
F
M
--
V
-----
M
F
M
H
M
A
K
G
L
----------
Y
Y
G
--
S
Y
R
S
P
R
----------------
V
----------------
T
L
W
N
--------------------
V
G
V
I
I
F
T
L
T
I
A
T
A
F
--
L
G
-------------------
Y
-
C
C
V
Y
G
Q
M
S
H
W
G
A
T
V
I
T
N
--
L
-
F
-
S
---
A
I
P
F
V
-----------
G
N
D
I
V
S
W
L
W
GGF
S
-----------
V
S
N
P
T
-------
I
Q
R
F
F
A
L
H
-
Y
L
V
P
F
----
I
I
--
A
A
M
V
I
M
H
L
--
M
--
A
L
H
I
H
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
Fugue
45.30
13%
-156
- C7 -
-
1KQF
3
FDNI_ECOLI
C:
[2-217]
------------------------------------------------------------------------------------------------------------------------------------------------------
S
K
S
K
-
M
I
V
R
T
K
F
I
---------------
D
R
A
C
H
W
T
V
------------
V
I
C
F
F
L
V
A
L
S
G
I
S
F
-
F
------
F
P
T
--
L
---
Q
----
W
-----------
L
--
T
Q
T
F
G
T
-------------
P
Q
M
G
R
I
L
H
P
------------------
F
F
G
I
A
I
--
F
-----
V
A
L
M
F
M
F
V
R
----------
F
V
H
--
H
N
I
P
D
K
----------------
K
D
I
--
P
W
----
L
L
N
---
I
V
E
V
L
K
GNEHKV
A
D
V
G
KYN
A
G
Q
K
M
M
F
W
S
I
M
S
M
I
F
V
L
L
V
--
T
G
-------------------
V
I
I
W
R
P
Y
F
A
Q
Y
F
------
P
--
M
-
Q
-
V
-
V
R
Y
S
L
L
I
-----------
H
-----------
A
-----------
A
A
G
I
I
-------
L
I
H
A
I
L
I
H
-
M
Y
M
A
F
W
V
KG
S
I
--
K
G
M
I
E
G
K
V
S
R
R
--
W
A
K
K
H
H
P
R
W
Y
------
R
E
I
-
E
K
A
E
A
K
K
--
E
S
E
E
GI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
43.87
32%
-280
* C6 *
-
4GD3
-
CYBH_ECOLI
A:
[189-210]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
----
L
I
--
G
A
F
V
I
G
H
V
--
Y
--
M
A
L
R
E
D
I
M
S
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
42.10
10%
-221
- C7 -
-
1KQG
3
FDNI_ECOLI
C:
[105-175]
-----------------------------------------------------------------------------------------------------------------------------------------------------------
D
V
G
K
Y
N
A
G
---------------
Q
K
M
M
F
W
S
I
------------
M
S
M
I
F
V
L
L
V
T
G
V
I
I
-
W
------
R
P
Y
--
F
---
A
----
Q
Y----------
F
--
P
M
Q
V
V
R
-------------
Y
S
L
L
I
H
A
A
A
------------------
G
I
I
L
I
H
--
A
-----
I
L
I
H
M
Y
M
A
F
----------
W
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
Fugue
40.27
20%
-55
- C3 -
-
5IRL
1
?
A:
[5-830]
EAA
A
C
K
K
Y
M
S
K
L
R
T
I
V
A
A
Q
S
R
F
LNLCLEDIY
T
E
N
T
L
E
V
R
TAALGLEELFSDAD
T
V
L
V
V
G
E
AGSG
K
S
T
L
L
Q
Q
V
H
L
L
W
A
T
GQDFQEFL
F
V
F
P
F
S
C
R
Q
L
Q
C
VAR
P
L
S
V
M
T
L
L
F
EHCCWPDVG
Q
Q
D
V
F
Q
F
L
L
D
H
PDR
I
L
L
T
F
D
GFDE
F
K
F
K
F
T
D
H
E
R
H
-
C
S
P
T
D
P
T
S
---------------
V
Q
T
L
L
F
N
L
------------
L
Q
-------------
G
------
N
L
L
KN
A
---
R
----
K
-----------
V
--
L
T
S
R
P
D
-------------
A
V
S
A
F
L
R
K
Y
------------------
V
R
T
E
F
N
--
L
K
G
F
S
E
E
G
I
E
L
Y
L
R
K
----------
C
H
R
--
E
P
G
V
A
D
----------------
R
L
I
--
H
L
----
L
Q
T
T
S
A
L
H
G
L
--------------------
C
H
L
P
V
F
S
W
M
V
S
K
C
H
--
Q
E
-------------------
L
-
L
L
Q
D
G
G
S
P
K
T
------
T
--
T
-
D
-
M
-
Y
L
L
I
L
Q
H
-----------
F
-----------
L
-----------
R
H
A
S
L
-------
L
Q
G
R
L
P
T
L
-
L
R
L
G
Q
----
L
A
L
W
G
L
G
M
C
C
Y
V
--
F
S
A
Q
Q
L
Q
A
A
Q
V
D
P
------
D
D
I
S
L
G
F
L
V
Q
A
--
P
L
E
F
LH
I
T
F
Q
C
F
L
A
A
F
Y
L
V
LSTDVPTASLRYLFNCS
T
V
A
A
L
L
Q
K
TE
P
H
N
L
Q
I
T
A
A
F
L
A
G
L
L
SREH
R
D
L
L
A
A
C
QASE
R
S
L
L
R
R
R
A
C
A
R
W
C
L
A
R
SLHKHFRSIPA
M
P
G
F
L
W
L
I
R
S
L
Y
E
M
QE
E
R
L
A
Q
E
A
V
RGLNVEHLKLTFCGVG
P
A
E
C
A
A
L
A
F
V
L
R
H
LRR
P
V
A
L
Q
LDHNSVG
D
I
G
V
E
Q
L
LPCLGACK
A
L
Y
L
R
DNNIS
D
R
G
I
C
K
L
I
E
H
A
L
H
CEQLQ
K
L
A
LFNNKLTDGC
A
H
S
V
A
Q
L
L
A
C
KQNF
L
A
L
R
LGNNHIT
A
E
G
A
Q
V
L
A
E
G
L
R
D
NSSLQ
F
L
G
FWGNKVG
D
K
G
A
Q
A
L
A
E
A
L
SDHQSLK
W
L
S
LVGNNIG
S
V
G
A
Q
A
L
A
S
M
L
E
K
NVALE
E
L
C
L
A
ANHLQ
D
A
G
V
C
S
L
A
E
G
L
K
R
NSSLK
V
L
K
L
S
NNCIT
F
V
G
A
E
A
L
L
Q
A
L
A
S
NDTIL
E
V
W
L
R
GNPFS
P
E
E
M
E
A
L
S
H
R
DSRLLL
33
Fugue
37.72
12%
-45
- C5 -
-
5HGZ
3
NAA60_HUMAN
A:
[2-212]
---------------------------------------------------------------------------------------------------------------------MT
E
E
E
R
S
S
A
L
S
E
V
S
L
R
L
L
C
HDD
I
D
T
V
K
H
L
C
G
D
W
F
P
I
E
Y
P
D
S
W
Y
R
D
I
---------------
T
S
N
K
K
F
F
S
------------
L
A
A
T
Y
R
G
A
I
V
G
M
I
V
-
A
------
E
I
K
--
N
---
R
----
T
-----------
K
--
I
H
K
E
D
G
-------------
D
I
L
A
S
N
F
S
V
------------------
D
T
Q
V
A
Y
--
I
-----
L
S
L
G
V
V
K
E
F
----------
R
K
H
G
I
G
S
L
L
L
E
----------------
S
L
K
--
D
H
----
I
S
T
---
T
A
Q
D
--------------------
H
C
K
A
I
Y
L
H
V
L
T
T
N
N
--
T
A
-------------------
I
-
N
F
Y
E
N
R
D
-------------------
F
K
Q
H
H
Y
-----------
L
-----------
P
-----------
Y
Y
Y
S
I
-------
R
G
V
L
K
D
G
F
-
T
Y
V
L
Y
----
I
N
--
G
----
G
H
P
--
P
--
W
T
I
L
D
Y
I
Q
H
L
------
G
S
A
-
L
A
S
L
S
P
C
SI
P
H
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
HHSearch
36.30
18%
-146
- C7 -
-
3CX5
-
CYB_YEAST
N:
[38-106]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
C
L
V
I
Q
I
V
--
T
G
-------------------
I
-
F
M
A
M
H
Y
S
S
N
I
------
E
L-
A
-
F
S
S
-
V
E
H
I
M
-------------------------------------
R
D
V
H
N
-------
G
Y
I
L
R
Y
L
H
-
A
N
G
A
S
----
F
F
--
F
M
V
M
F
M
H
M
--
A
--
K
G
L
Y
Y
G
S
Y
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
Fugue
35.72
16%
-39
- C2 -
-
5J9T
-
EPL1_YEAST
C:
[8-279]
----------------------------------------------------------------------------------------------------------------------------------------MTWNE
Y
D
K
F
Y
T
G
S
F
Q
E
T
T
-
S
Y
I
K
F
S
A
T
VEDCCGTN
Y
N
M
D
E
R
D
E
T
F
L
N
E
Q
V
NKGSS
D
I
L
T
E
D
E
F
E
I
L
C
S
S
F
E
H
A
I
H
E
R
Q
------
P
F
L
--
S
---
M
----
D
-----------
P
--
E
S
I
L
---------------
S
F
E
E
L
K
P
T
L
------------------
I
K
S
D
M
A
--
D
-----
F
N
L
R
N
Q
L
N
H
E
I
NSHKTHFI
T
Q
F
--
D
P
V
S
Q
M
----------------
N
T
R
--
P
L
----
I
Q
L
---
I
E
K
F
--------------------
G
S
K
I
Y
D
Y
W
R
E
R
K
I
E
--
V
N
GYEIFPQ
L
K
F
E
R
PGIDPYV
C
-
F
R
R
R
E
V
R
H
P
R
------
K
T
R
R
-
I
-
D
-
I
L
N
S
Q
R
L
-----------
R
-----------
A
-----------
L
H
Q
E
L
K
N
A
K
D
L
A
L
L
V
A
K
R
E
N
-
V
S
L
N
W
----
I
N
--
D
E
L
K
I
F
D
Q
--
R
--
V
K
I
K
N
L
K
R
S
L
NISGED
D
D
L
-
I
N
H
K
R
K
R
--
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------