@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : I3TY80: (2017-12-14 )
MTEKGVETMKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKKYLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGALLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGSFYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGVADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEMDYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE
Atome Classification :
(20 SA)
------.........10.......-.20........30.....-...40........50....----.----..---.-60........70--.----.---------.-------------..-.-----------...80----------........90........100...--.--...-110.-..-------.------....120---.....---.-----.130.-.--.....-140.......------.-.----150-----.-......160.......170.......180....----...190-----..-.---.--.---.---...200.......----210........220------------.--------------...----.....230-...-....240.......250.......260.......270---.......280......-.290.......300.......310----------.........320.......330....--...340
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
------MTEKG
V
E
T
M
K
I
A
V
D
AMGG-DH
A
P
Q
A
I
V
E
G
V
A
L
A
Q
QDF-PE
V
E
F
L
L
YG
K
E
A
E
I
K
K
Y
LT----N----EK---
N
-
I
T
I
I
HTDEKIN---S----D---------D-------------
E
P
-
V
-----------
K
A
I
R
R
----------
K
K
T
A
S
M
V
L
A
A
Q
A
VKNGEA
D
A
V
FSA--G--N
T
G
-
A
-
L
L
-
A
A
-------
G
------
L
F
I
V
G
R
I---KNIER---P-----GLMST-L--PVVGK-E--GAGF
D
M
L
------D-L----GAN-----A-EN
K
P
E
H
L
L
Q
Y
G
I
L
G
S
F
Y
A
R
K
V
RGIGRP
R
V
A
L
LN----NGTE-------AT-K---G--
S
---
E
---
V
T
K
K
A
Y
E
L
L
QNET----SL-
N
F
IGNV
E
A
R
--------------
E
--------------
L
L
N
----
G
V
A
D
V
V
VT-DGF-T
G
N
A
V
L
K
S
I
E
G
T
A
M
N
M
M
N
L
L
K
S
A
I
LNEGIKG
K
M
G
A
M
L
---
L
K
D
G
L
R
S
L
K
A
EMDYSK-HG
G
A
V
L
F
GLKA
P
V
I
KTHGAT
G
P
------------
D
A
V
R
Y
T
I
R
Q
I
H
T
M
L
E
T
D
V
V
G
Q
L
V
E
Q
F
--
E
KSEE
1
PsiBlast_PDB
86.25
50%
-27
- C- -
-
1VI1
-
PLSX_BACSU
A:
[0-333]
-------------
S
L
R
I
A
V
D
A
M
G
G
-
D
H
A
P
K
A
V
I
D
G
V
I
K
G
I
E
A
F
-
D
D
L
H
I
T
L
V
G
D
K
T
T
I
E
S
H
L
T
----
T
----
T
S
---
D
R
I
T
V
L
H
A
D
E
V
I
E
---
P
----
T
---------
D
-------------
E
P
-
V
-----------
R
A
V
R
R
----------
K
K
N
S
S
M
V
L
M
A
Q
E
V
A
E
N
R
A
D
A
C
I
S
A
--
G
--
N
T
G
-
A
-
L
M
-
T
A
-------
G
------
L
F
I
V
G
R
I
---
K
G
I
D
R
---
P
-----
A
L
A
P
T
-
L
--
P
T
V
---
S
--
G
D
G
F
L
L
L
------
D
-
V
----
G
A
N
-----
V
-
D
A
K
P
E
H
L
V
Q
Y
A
I
M
G
S
V
Y
S
Q
Q
V
R
G
V
T
S
P
R
V
G
L
L
N
----
V
G
T
E
-------
D
K
-
K
---
G
--
N
---
E
---
L
T
K
Q
T
F
Q
I
L
K
E
T
A
----
N
I
-
N
F
I
G
N
V
E
A
R
--------------
D
--------------
L
L
D
----
D
V
A
D
V
V
V
T
-
D
G
F
-
T
G
N
V
T
L
K
T
L
E
G
S
A
L
S
I
F
K
M
M
R
D
-
V
M
T
S
T
L
-------
V
---
L
K
P
K
L
K
E
M
K
M
K
M
E
Y
S
N
-
Y
G
G
A
S
L
F
G
L
K
A
P
V
I
K
A
H
G
S
S
D
S
------------
N
A
V
F
R
A
I
R
Q
A
R
E
M
V
S
Q
N
V
A
A
L
I
Q
E
E
V
K
E
E
K
T
D
E
32
HHSearch
83.49
51%
-15
- C- -
-
1VI1
-
PLSX_BACSU
B:
[0-328]
-------------
S
L
R
I
A
V
D
A
M
G
G
-
D
H
A
P
K
A
V
I
D
G
V
I
K
G
I
E
A
F
-
D
D
L
H
I
T
L
V
G
D
K
T
T
I
E
S
H
L
T
----
T
T---
S
D
---
R
-
I
T
V
L
H
A
D
E
V
I
E
---
P
----
T
---------
D
-------------
E
P
-
V
-----------
R
A
V
R
R
----------
K
K
N
S
S
M
V
L
M
A
Q
E
V
A
E
N
R
A
D
A
C
I
S
A
--
G
--
N
T
G
-
A
-
L
M
-
T
A
-------
G
------
L
F
I
V
G
R
I
---
K
G
I
D
R
---
P
-----
A
L
A
P
T
-
L
--
P
T
V
S
G
-----
D
G
F
L
L
L
------
D
-
V
----
G
A
N
-----
V
-
D
A
K
P
E
H
L
V
Q
Y
A
I
M
G
S
V
Y
S
Q
Q
V
R
G
V
T
S
P
R
V
G
L
L
N
----
V
G
T
E
-------
D
K
-
K
---
G
--
N
---
E
---
L
T
K
Q
T
F
Q
I
L
K
E
T
A
-----
N
I
N
F
I
G
N
V
E
A
R
--------------
D
--------------
L
L
D
----
D
V
A
D
V
V
V
T
-
D
G
F
-
T
G
N
V
T
L
K
T
L
E
G
S
A
L
S
I
F
K
M
M
R
D
V
M
T
S
-
T
L
T
S
-----------
P
K
L
K
E
M
K
M
K
M
E
Y
S
N
-
Y
G
G
A
S
L
F
G
L
K
A
P
V
I
K
A
H
G
S
S
D
S
------------
N
A
V
F
R
A
I
R
Q
A
R
E
M
V
S
Q
N
V
A
A
L
I
Q
E
E
V
--
K
E
---
31
HHSearch
82.60
51%
-9
- C- -
-
1VI1
-
PLSX_BACSU
A:
[0-330]
-------------
S
L
R
I
A
V
D
A
M
G
G
-
D
H
A
P
K
A
V
I
D
G
V
I
K
G
I
E
A
F
-
D
D
L
H
I
T
L
V
G
D
K
T
T
I
E
S
H
L
T
----
T
T---
S
D
---
R
-
I
T
V
L
H
A
D
E
V
I
E
---
P
----
T
---------
D
-------------
E
P
-
V
-----------
R
A
V
R
R
----------
K
K
N
S
S
M
V
L
M
A
Q
E
V
A
E
N
R
A
D
A
C
I
S
A
--
G
--
N
T
G
-
A
-
L
M
-
T
A
-------
G
------
L
F
I
V
G
R
I
---
K
G
I
D
R
---
P
-----
A
L
A
P
T
-
L
--
P
T
V
S
G
-----
D
G
F
L
L
L
------
D
-
V
----
G
A
N
-----
V
-
D
A
K
P
E
H
L
V
Q
Y
A
I
M
G
S
V
Y
S
Q
Q
V
R
G
V
T
S
P
R
V
G
L
L
N
----
V
G
T
E
-------
D
K
-
K
---
G
--
N
---
E
---
L
T
K
Q
T
F
Q
I
L
K
E
T
A
-----
N
I
N
F
I
G
N
V
E
A
R
--------------
D
--------------
L
L
D
----
D
V
A
D
V
V
V
T
-
D
G
F
-
T
G
N
V
T
L
K
T
L
E
G
S
A
L
S
I
F
K
M
M
R
D
V
M
T
S
-
T
L
-------
V
---
L
K
P
K
L
K
E
M
K
M
K
M
E
Y
S
N
-
Y
G
G
A
S
L
F
G
L
K
A
P
V
I
K
A
H
G
S
S
D
S
------------
N
A
V
F
R
A
I
R
Q
A
R
E
M
V
S
Q
N
V
A
A
L
I
Q
E
E
V
--
K
E
E
K
-
35
HHSearch
59.01
23%
-42
- C3 -
-
3UF6
1
?
A:
[17-290]
------------
S
S
F
V
F
A
V
A
G
A
D
D
-----
E
V
V
L
E
T
I
R
L
A
L
K
Q
K
--
L
G
K
F
L
L
F
G
K
K
E
D
K
T
L
T
A
----------
N
E
---
S
-
V
T
W
I
Q
T
D
T
------------------------------------
A
-
E
-----------
A
A
A
-
Q
-----------------
G
A
I
L
A
V
K
N
K
E
A
D
I
L
V
K
G
--
F
--
I
P
T
-
A
T
L
M
-----------------
H
H
V
L
K
K
E
---
N
G
L
R
T
D
Q
L
L
-----
S
Q
I
A
I
-
F
DI
P
T
Y
-
H
-----
K
P
L
L
I
T
------
D
-
C
----
A
M
N
-----
V
-
A
P
K
T
K
E
K
I
A
I
T
E
N
A
L
A
V
A
H
Q
-
I
G
I
T
N
P
K
I
A
L
L
S
----
A
V
E
E
-------
V
T
-
A
---
K
--
M
---
P
---
S
T
L
E
A
Q
E
V
V
Q
H
F
G
----
N
Q
I
S
V
S
G
P
L
A
L
D
VAIS
K
E
A
A
L
H
K
GIT
D
--------------
S
S
A
----
G
E
A
D
I
L
I
A
P
N
I
E
-
T
G
N
A
L
Y
K
S
L
V
------------
Y
F
A
----------------------------
G
A
K
--
V
G
S
A
V
V
G
A
K
V
P
I
V
I
S
S
R
N
D
S
P
------------
E
N
K
L
A
S
F
I
L
T
V
R
L
V
E
------------------
34
HHSearch
57.96
23%
-46
- C3 -
-
3U9E
14
?
B:
[17-290]
------------
S
S
F
V
F
A
V
A
G
A
D
D
-----
E
V
V
L
E
T
I
R
L
A
L
K
Q
K
--
L
G
K
F
L
L
F
G
K
K
E
D
K
T
L
T
A
----------
N
E
---
S
-
V
T
W
I
Q
T
D
T
------------------------------------
A
-
E
-----------
A
A
A
-
Q
-----------------
G
A
I
L
A
V
K
N
K
E
A
D
I
L
V
K
G
--
F
--
I
P
T
-
A
T
L
M
-----------------
H
H
V
L
K
K
E
---
N
G
L
R
T
D
Q
L
L
-----
S
Q
I
A
I
-
F
DI
P
T
Y
-
H
-----
K
P
L
L
I
T
------
D
-
C
----
A
M
N
-----
V
-
A
P
K
T
K
E
K
I
A
I
T
E
N
A
L
A
V
A
H
Q
-
I
G
I
T
N
P
K
I
A
L
L
S
----
A
V
E
E
-------
V
T
-
A
---
K
--
M
---
P
---
S
T
L
E
A
Q
E
V
V
Q
H
F
G
----
N
Q
I
S
V
S
G
P
L
A
L
D
VAIS
K
E
A
A
L
H
K
GIT
D
--------------
S
S
A
----
G
E
A
D
I
L
I
A
P
N
I
E
-
T
G
N
A
L
Y
K
S
L
V
------------
Y
F
A
----------------------------
G
A
K
--
V
G
S
A
V
V
G
A
K
V
P
I
V
I
S
S
R
N
D
S
P
------------
E
N
K
L
A
S
F
I
L
T
V
R
L
V
E
------------------
38
HHSearch
57.71
18%
-17
* C3 *
-
1VMI
2
EUTD_ECOLI
A:
[25-335]
------------
A
P
A
R
V
V
F
P
D
A
L
D
-----
Q
R
V
L
K
A
A
Q
Y
L
H
Q
Q
G
--
L
A
T
P
I
L
V
A
N
P
F
E
L
R
Q
F
A
L
S
H
GV
A
----
M
D
---
G
-
L
Q
V
I
D
P
H
G
N
L
A
---
M
R
E
E
F
A
H
R
W
L
A
R
AGE
K
-------------
T
P
-
P
-----------
D
A
L
E
-----------
K
L
T
D
P
L
M
F
A
A
A
M
V
S
A
G
K
A
D
V
C
I
A
G
--
N
LS
S
T
A
-
N
-
V
L
-
R
A
-------
G
------
L
R
I
I
G
L
Q
---
P
G
C
K
T
---
L
-----
S
S
I
F
L
M
L
--
P
Q
Y
S
G
-----
P
A
L
G
F
A
------
D
-
C
----
S
V
V
-----
P
-
Q
P
T
A
A
Q
L
A
D
I
A
L
A
S
A
E
T
W
R
A
I
T
G
-
E
E
P
R
V
A
M
L
S
----
F
S
S
N
-------
G
S
-
A
RH
P
C
--
V
---
A
---
N
V
Q
Q
A
T
E
I
V
R
E
R
A
----
P
K
L
V
V
D
G
E
L
Q
F
D
A
A
F
V
P
E
V
A
A
Q
KAPA
S
--------------
P
L
Q
----
G
K
A
N
V
M
V
F
P
S
L
E
-
A
G
N
I
G
Y
K
I
A
Q
------------
R
L
G
----------------------------
G
Y
R
-
A
V
G
P
L
I
Q
G
L
A
A
P
M
H
D
L
S
R
G
C
S
V
------------
Q
E
I
I
E
L
A
L
V
A
A
V
P
R
-------------------
41
HHSearch
54.87
17%
-15
- C3 -
-
1QZT
-
PTAS_METTE
A:
[15-330]
------------
L
N
K
T
I
A
L
P
E
T
E
D
-----
I
R
T
L
Q
A
A
A
K
I
L
E
R
G
--
I
A
D
I
V
L
V
G
N
E
A
D
I
K
A
L
A
G
DL--
D
----
L
S
---
K
-
A
K
I
V
D
P
K
T
Y
E
K
K
D
E
Y
----
I
-----------------------
N
A
-
F
Y
E
L
R
KHKGIT
L
E
N
A
A
E
----------
I
M
S
D
Y
V
Y
F
A
V
M
M
A
K
L
G
E
V
D
G
V
V
S
G
--
A
AH
S
S
S
-
D
-
T
L
-
R
P
-------
A
------
V
Q
I
V
K
T
A
---
K
G
A
A
L
---
A
-----
S
A
F
F
I
-
I
--
S
V
P
D
C
E
Y
GS
D
G
T
F
L
F
A
------
D
-
S
----
G
M
V
-----
E
-
M
P
S
V
E
D
V
A
N
I
A
V
I
S
A
K
T
F
E
L
-
L
V
Q
D
V
P
K
V
A
M
L
S
----
Y
S
T
K
-------
G
S
A
K
---
S
K
L
T
---
E
---
A
T
I
A
S
T
K
L
A
Q
E
L
A
----
P
D
I
A
I
D
G
E
L
Q
V
D
AAIV
P
K
V
A
A
S
KAPG
S
--------------
P
V
A
----
G
K
A
N
V
F
I
F
P
D
L
N
-
C
G
N
I
A
Y
K
I
A
Q
------------
R
L
A
----------------------------
K
A
E
-
A
Y
G
P
I
T
Q
G
L
A
K
P
I
N
D
L
S
R
G
C
S
D
------------
E
D
I
V
G
A
V
A
I
T
C
V
Q
A
A
A
-----------------
42
HHSearch
54.76
17%
-17
- C3 -
-
2AF4
2
PTAS_METTE
C:
[15-330]
------------
L
N
K
T
I
A
L
P
E
T
E
D
-----
I
R
T
L
Q
A
A
A
K
I
L
E
R
G
--
I
A
D
I
V
L
V
G
N
E
A
D
I
K
A
L
A
G
DL--
D
----
L
S
---
K
-
A
K
I
V
D
P
K
T
Y
E
K
KDE
Y
----
I
-----------------------
N
A
-
F
YELRKHKGITL
E
N
A
A
E
----------
I
M
S
D
Y
V
Y
F
A
V
M
M
A
K
L
G
E
V
D
G
V
V
S
G
--
A
AH
S
S
S
-
D
-
T
L
-
R
P
-------
A
------
V
Q
I
V
K
T
A
---
K
G
A
A
L
---
A
-----
S
A
F
F
I
-
I
--
S
V
P
D
C
E
Y
GS
D
G
T
F
L
F
A
------
D
-
S
----
G
M
V
-----
E
-
M
P
S
V
E
D
V
A
N
I
A
V
I
S
A
K
T
F
E
L
-
L
V
Q
D
V
P
K
V
A
M
L
S
----
Y
S
T
K
-------
G
S
A
K
---
S
KL
T
---
E
---
A
T
I
A
S
T
K
L
A
Q
E
L
A
----
P
D
I
A
I
D
G
E
L
Q
V
D
AAIVPKVAASKAPG
S
--------------
P
V
A
----
G
K
A
N
V
F
I
F
P
D
L
N
-
C
G
N
I
A
Y
K
I
A
Q
------------
R
L
A
----------------------------
K
A
E
-
A
Y
G
P
I
T
Q
G
L
A
K
P
I
N
D
L
S
R
G
C
S
D
------------
E
D
I
V
G
A
V
A
I
T
C
V
Q
A
A
A
-----------------
37
HHSearch
54.11
19%
10
- C3 -
-
4E4R
6
PTAS_STAAR
A:
[19-330]
-------------
N
V
K
I
V
L
P
E
G
E
D
-----
E
R
V
L
T
A
A
T
Q
L
Q
A
T
D
--
Y
V
T
P
I
V
L
G
D
E
T
K
V
Q
S
L
A
Q
K
L
NL
D
----
I
S
---
N
-
I
E
L
I
N
P
A
T
S
E
L
---
K
----
A
---------
E
L
V
Q
S
F
V
E
R
R
K
GKT
T
E
-
E
-----------
Q
A
Q
-
E
----------
L
L
N
N
V
N
Y
F
G
T
M
L
V
Y
A
G
K
A
D
G
L
V
S
G
AA
H
--
S
T
G
-
D
-
T
V
-
R
P
-------
A
------
L
Q
I
I
K
T
K
---
P
G
V
S
R
---
T
-----
S
G
I
F
F
-
M
--
I
K
G
-
D
-----
E
Q
Y
I
F
G
------
D
-
C
----
A
I
N
-----
P
-
E
L
D
S
Q
G
L
A
E
I
A
V
E
S
A
K
S
A
L
S
-
F
G
M
-
D
P
K
V
A
M
L
S
----
F
S
T
K
-------
G
S
-
A
---
K
--
S
D
D
V
T
---
K
V
Q
E
A
V
K
L
A
Q
Q
K
A
E
E
E
K
L
E
A
I
I
D
G
E
F
Q
F
D
AAIV
P
G
V
A
E
K
KAPG
A
--------------
K
L
Q
----
G
D
A
N
V
F
V
F
-
P
S
L
E
A
G
N
I
G
Y
K
I
A
Q
------------
R
L
G
----------------------------
G
Y
D
-
A
V
G
P
V
L
Q
G
L
N
S
P
V
N
D
L
S
R
G
C
S
I
------------
E
D
V
Y
N
L
S
F
I
T
A
A
Q
A
L
------------------
36
HHSearch
51.58
18%
-22
- C3 -
-
1YCO
-
?
A:
[1-275]
-------------
M
I
T
V
S
I
A
G
G
S
Q
-----
P
E
I
L
Q
L
V
K
K
A
L
K
E
A
E
Q
P
L
Q
F
I
V
F
D
T
N
E
N
L
D
T
------------
E
N
---
L
-
W
K
Y
V
H
C
S
D
------------------------------------------------------------------
E
A
A
V
A
Q
E
A
V
S
L
V
A
T
G
Q
A
Q
I
L
L
K
G
--
I
--
I
Q
T
H
T
-
L
L
-
K
E
-------
M
------
L
K
S
E
H
Q
L
KNK
P
I
L
S
H
---
V
-----
A
M
V
-
E
-
L
--
P
A
--
G
-----
K
T
F
L
L
T
------
D
-
C
----
A
M
N
-----
I
-
A
P
T
Q
A
T
L
I
E
I
V
E
N
A
K
E
V
A
Q
K
-
L
G
L
H
H
P
K
I
A
L
L
S
----
A
A
E
N
-------
F
N
-
P
KM
P
S
--
S
---
V
---
L
A
K
E
V
T
A
H
F
N
D
Q
-----
Q
E
A
T
V
F
G
P
L
S
L
D
--------------
L
ATS
E
E
A
V
A
H
K
RYSG
P
I
M
----
G
D
A
D
I
L
V
V
P
T
I
D
-
V
G
N
C
L
Y
K
S
L
T
L
------------
F
G
----------------------------
H
A
K
-
V
-
G
G
T
I
V
G
T
K
V
P
V
V
L
T
S
R
S
D
S
T
------------
E
S
K
F
H
S
L
R
F
A
M
R
Q
V
H
H
-----------------
43
HHSearch
50.92
20%
12
- C3 -
-
1R5J
-
?
A:
[17-328]
------------
K
N
M
K
I
V
F
P
E
-
G
N
----
D
E
R
V
V
R
A
A
A
R
L
K
F
E
G
--
L
L
E
P
I
I
L
G
Q
S
E
E
V
R
N
L
L
T
----
K
L
GFA
D
Q
---
D
-
Y
T
I
I
N
P
N
E
Y
A
D
---
F
----
D
---------
K
M
K
-----------
E
A
-
F
-----------
V
E
V
R
K
GKAT
L
E
D
A
D
K
M
L
R
D
V
N
Y
F
G
V
M
L
V
K
M
G
L
A
D
G
M
V
S
G
--
A
IH
S
T
A
-
D
-
T
V
-
R
P
-------
A
------
L
Q
I
I
K
T
K
---
P
G
I
S
R
---
T
-----
S
G
V
F
L
-
M
--
N
R
E
N
--
T
--
S
E
R
Y
V
F
A
------
D
-
C
----
A
I
N
-----
I
-
D
P
T
A
Q
E
L
A
E
I
A
V
N
T
A
E
T
A
K
I
-
F
D
I
-
D
P
K
I
A
M
L
S
----
F
S
T
K
-------
G
S
-
G
---
K
--
A
P
Q
V
D
---
K
V
R
E
A
T
E
I
A
T
G
L
N
----
P
D
L
A
L
D
G
E
L
Q
F
D
A
A
F
V
P
E
T
A
A
I
KAPD
S
--------------
A
V
A
----
G
Q
A
N
T
F
V
F
P
D
L
Q
-
S
G
N
I
G
Y
K
I
A
Q
------------
R
L
G
----------------------------
M
F
D
-
A
I
G
P
I
L
Q
G
L
N
K
P
V
N
D
L
S
R
G
S
S
A
------------
E
D
I
Y
K
L
A
I
I
T
A
A
Q
A
I
E
-----------------
40
HHSearch
48.82
18%
4
- C3 -
-
1XCO
4
PTAS_BACSU
D:
[22-328]
-------------
D
V
K
I
V
F
P
E
G
L
-----
D
E
R
I
L
E
A
V
S
K
L
A
G
N
K
--
V
L
N
P
I
V
I
G
N
E
N
E
I
Q
A
K
A
K
ELNL
T
----
L
G
---
G
-
V
K
I
Y
D
P
H
T
Y
E
G
---
M
----
E
---------
D
LVQAFVERRKGKA
T
E
-
E
-----------
Q
A
R
-
K
----------
A
L
L
D
E
N
Y
F
G
T
M
L
V
Y
K
G
L
A
D
G
L
V
S
G
--
A
AH
S
T
A
-
D
-
T
V
-
R
P
-------
A
------
L
Q
I
I
K
T
K
---
E
G
V
K
K
---
T
-----
S
G
V
F
I
-
M
--
A
R
G
-
E
-----
E
Q
Y
V
F
A
------
D
-
C
----
A
I
N
-----
I
-
A
P
D
S
Q
D
L
A
E
I
A
I
E
S
A
N
T
A
K
M
-
F
D
I
-
E
P
R
V
A
M
L
S
----
F
S
T
K
-------
G
S
-
A
---
K
--
S
---
D
ETE
K
V
A
D
A
V
K
I
A
K
E
K
A
----
P
E
L
T
L
D
G
E
F
Q
F
D
AAFVPSVAEKKAPD
S
--------------
E
I
K
----
G
D
A
N
V
F
V
F
-
P
S
L
E
A
G
N
I
G
Y
K
I
A
Q
------------
R
L
G
----------------------------
N
F
E
-
A
V
G
P
I
L
Q
G
L
N
M
P
V
N
D
L
S
R
G
C
N
A
------------
E
D
V
Y
N
L
A
L
I
T
A
A
Q
A
-------------------
23
Fugue
43.86
18%
72
- C3 -
-
3TNG
5
?
A:
[5-291]
TKSRFF
S
D
V
A
E
T
S
S
F
V
F
A
V
A
G
A
D
D
-
E
V
V
L
E
T
I
R
L
A
L
K
Q
K
L
------
G
K
F
L
L
F
G
K
K
E
D
K
T
L
--
T
----
A
----
N
E
---
S
-
V
T
W
I
Q
T
D
T
------------------------------------------------------------------
A
E
A
A
A
Q
G
A
I
L
A
V
K
N
K
E
A
D
I
L
V
K
G
--
F
--
I
P
T
-
A
-
T
L
M
H
H
----------------
V
L
K
K
E
---
N
G
L
R
T
---
D
-----
Q
L
L
S
Q
-
I
--
A
I
F
D
I
-
P
--
T
Y
H
K
P
L
L
------
I
-
T
----
D
C
A
M----
N
-
V
A
P
K
T
K
E
K
I
A
I
T
E
N
A
L
A
V
A
H
Q
I
G
I
T
N
P
K
I
A
L
L
S
----
A
V
E
E
-------
V
T
-
A
---
K
M-
P
------------------------------
S
T
L
E
A
Q
--------------
E
--------------
V
V
Q
----
H
F
G
N
Q
I
S
V
-
S
G
P
-
L
A
L
D
V
A
I
S
K
E
A
A
L
H
K
G
--------
I
T
D
S
S
A
G
E
A
D
I
L
I
A
PN
I
E
T
G
N
A
L
Y
K
S
L
V
Y
F
A
G
A
K
V
G
S
A
V
V
G
A
K
V
P
I
V
I
S
S
R
N
D
S
P
------------
E
N
K
L
A
S
F
I
L
T
V
R
L
V
E
K
-----------------
44
HHSearch
43.24
19%
31
- C3 -
-
4JQP
1
?
B:
[15-341]
-------------
L
P
V
I
G
I
T
M
G
D
A
A
G
V
G
A
E
V
V
V
K
S
L
A
H
A
S
V
Y
A
--
Q
C
R
P
L
V
I
G
D
A
K
R
L
E
R
A
N
Q
----
I
----
V
G
GEM
K
-
I
R
R
I
E
D
A
S
E
A
R
---
Y
----
E
QGTI-----
D
CI-----------
D
L
G
L
IP---------
D
D
L
P
F
GQLSAIAGD-
A
A
Y
Q
Y
I
K
R
A
V
E
L
A
Q
S
G
K
I
D
A
I
C
T
A
--
P
L-
N
K
E
-
A
-
L
H
-
A
G
-------
G
------
H
K
Y
P
G
H
T
---
E
M
L
A
H
---
L
TGVDE
V
S
M
M
L
-
V
--
A
P
Q
-
L
-----
R
V
I
H
V
T
------
T
H
I
----
G
I
I
DAIRK
I
E
P
G
L
V
Q
R
T
I
E
R
G
N
---
A
T
L
V
K
-
A
G
I
E
R
P
R
I
G
V
C
G
----
I
N
P
H
AGENGLF
G
Y
G
E
---
E
--
E
---
E
---
K
I
I
P
A
V
T
L
L
Q
E
R
------
G
L
D
V
T
G
P
L
P
A
D
--------------
T
--------------
L
F
F
RAGR
G
D
F
D
L
V
V
A
M
Y
H
D
-
Q
G
H
G
P
V
K
V
L
------------
G
-----------------------------------
L
E
A
G
V
N
V
T
V
G
L
E
V
I
R
T
S
V
D
H
G
T
AFDIAGKGVVDE
G
S
M
L
E
A
L
R
Q
G
A
E
L
A
T
R
-----------------
49
HHSearch
36.96
22%
-11
- C3 -
-
1YXO
5
PDXA_PSEAE
A:
[99-275]
------------------------------------------------------------------------------------------------------------------------------------------------------------
T
L
T
R
A
G
Q
G
C
L
D
G
H
F
A
G
M
I
T
A
--
P
V-
H
K
G
-
V
-
I
N
-
E
A
-------
G
IPFSG
H
T
E
F
L
A
D
L
---
T
H
T
A
Q
---------
V
V
M
-
M
-
L
--
A
T
R
G
L
-----
R
V
A
L
A
T
------
T
-
H
LPLR
E
V
A
-----
D
-
A
I
S
D
E
R
L
T
R
V
A
R
I
L
H
A
D
L
R
D
K
F
G
I
A
H
P
R
I
L
V
C
G
LNPH
A
G
E
G
-------
G
H
-
L
---
G
--
R
EEI
E
---
V
I
E
P
C
L
E
R
L
R
G
------
E
G
L
D
L
I
G
P
L
P
A
D
--------------
T
--------------
L
F
T
P
K
H
L
E
H
C
D
A
V
L
A
M
Y
H
D
-
Q
G
L
P
V
L
K
Y
K
-------------------------------------------------------------------------------------------------------------------
51
HHSearch
35.95
15%
-171
- C3 -
-
3TSN
2
PDXA_CAMJE
C:
[277-314]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
L
P
Y
P
L
V
A
D
--------------
T
--------------
A
F
T
KTGL
K
N
C
N
R
L
V
A
M
Y
H
D
-
L
A
L
A
P
L
K
A
L
-------------------------------------------------------------------------------------------------------------------
50
HHSearch
34.31
18%
-12
- C3 -
-
3LXY
1
PDXA_YERPE
A:
[104-280]
------------------------------------------------------------------------------------------------------------------------------------------------------------
T
L
A
K
A
C
D
G
A
I
S
G
E
F
A
A
L
V
T
G
--
P
V-
Q
K
S
-
I
-
I
N
-
D
A
-------
G
IPFIG
H
T
E
F
F
A
D
R
---
S
H
C
Q
R
---
V
------
V
M
M
L
-
A
---
T
E
E
L
-----
R
V
A
L
A
T
------
T
-
H
LPLL
A
V
P
-----
G
-
A
I
T
Q
A
S
L
H
E
V
I
T
I
L
D
N
D
L
K
T
K
F
G
I
T
Q
P
Q
I
Y
V
C
G
LNPH
A
G
E
G
-------
G
H
-
M
---
G
--
H
EEI
D
---
T
I
I
P
A
L
N
T
L
R
Q
Q
------
G
I
N
L
I
G
P
L
P
A
D
--------------
T
--------------
L
F
Q
P
K
Y
L
Q
H
A
D
A
V
L
A
M
Y
H
D
-
Q
G
L
P
V
L
K
Y
Q
-------------------------------------------------------------------------------------------------------------------
46
HHSearch
33.10
18%
10
- C- -
-
2HI1
-
PDXA2_SALTY
B:
[103-279]
------------------------------------------------------------------------------------------------------------------------------------------------------------
C
V
K
R
A
T
E
L
A
L
R
G
D
V
Q
A
I
A
T
A
--
P
L-
N
K
E
-
A
-
L
H
-
L
A
-------
G
HNYPG
H
T
E
L
L
A
T
L
---
T
H
S
R
D
---------
Y
A
M
-
V
-
L
--
Y
T
D
K
L
-----
K
V
I
H
V
S
THIA
L
R
K
-
F
----
L
-------
D
-
T
L
S
T
A
R
V
E
T
V
I
G
I
A
D
T
F
L
K
R
-
V
G
Y
V
K
P
R
I
A
V
A
G
VNPH
A
G
----------
L
-
F
---
G
--
D
---
E
ETR
I
L
T
P
A
I
T
D
A
R
A
K
------
G
M
D
V
Y
G
P
C
P
P
D
--------------
T
--------------
V
F
L
Q
A
Y
E
G
Q
Y
D
M
V
V
A
M
Y
H
D
-
Q
G
H
I
P
L
K
L
L
-------------------------------------------------------------------------------------------------------------------
48
HHSearch
33.01
17%
12
- C3 -
-
1PTM
-
PDXA_ECOLI
A:
[100-276]
------------------------------------------------------------------------------------------------------------------------------------------------------------
T
L
A
R
A
C
D
G
C
L
N
G
E
F
A
A
L
I
T
G
--
P
--
V
H
K
-
G
-
V
I
-
N
D
A
GIPFTG
H
------
T
E
F
F
E
E
R
---
S
Q
A
K
K
---------
V
V
M
M
L
-
A
---
T
E
E
L
-----
R
V
A
L
A
T
------
T
-
H
LPLR
D
I
A
-----
D
-
A
I
T
P
A
L
L
H
E
V
I
A
I
L
H
H
D
L
R
T
K
F
G
I
A
E
P
R
I
L
V
C
G
LNPH
A
G
E
G
-------
G
H
-
M
---
G
--
T
EEI
D
---
T
I
I
P
V
L
N
E
L
R
A
Q
------
G
M
K
L
N
G
P
L
P
A
D
--------------
T
--------------
L
F
Q
PKYL
D
N
A
D
A
V
L
A
M
Y
H
D
-
Q
G
L
P
V
L
K
Y
Q
-------------------------------------------------------------------------------------------------------------------
47
HHSearch
32.37
18%
14
- C- -
-
2HI1
-
PDXA2_SALTY
A:
[103-279]
------------------------------------------------------------------------------------------------------------------------------------------------------------
C
V
K
R
A
T
E
L
A
L
R
G
D
V
Q
A
I
A
T
A
--
P
L-
N
K
E
-
A
-
L
H
-
L
A
-------
G
HNYPG
H
T
E
L
L
A
T
L
---
T
H
S
R
D
---------
Y
A
M
-
V
-
L
--
Y
T
D
K
L
-----
K
V
I
H
V
S
THIA
L
R
K
-
F
----
L
-------
D
-
T
L
S
T
A
R
V
E
T
V
I
G
I
A
D
T
F
L
K
R
-
V
G
Y
V
K
P
R
I
A
V
A
G
VNPH
A
G
E
N
-------
G
L
-
F
---
G
--
D
---
E
E
T
R
I
L
T
P
A
I
T
D
A
R
A
K
------
G
M
D
V
Y
G
P
C
P
P
D
--------------
T
--------------
V
F
L
Q
A
Y
E
G
Q
Y
D
M
V
V
A
M
Y
H
D
-
Q
G
H
I
P
L
K
L
L
-------------------------------------------------------------------------------------------------------------------