@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Q3Y131: (2018-01-23 )
MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEFTNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDINMGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISHLLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGEELAEKYGVDGIMIGRGIFKNPYAFEKDPREHTEKELIGLLRLQLDLQDHYSEIIPRSITGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILETFEKEHPTLFSEQ
Atome Classification :
(20 SA)
.........10........20........30....-....40.....---------------.----------..50....-.---...-------60---.------.--------....-...70........80........90.........100.......110.......120...---....130.---...---.--...140.....------..150-.---........160----.........170.......180-------.-.-.....190.......200.......210--.........220.......230.......---240-.--..---...--------.250.......260.......270.-----.--.....280.......290.......300.......310.......320.....
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MT
T
N
F
W
K
ELPK
P
F
F
V
LA
P
M
E
D
V
T
D
V
V
F
R
H
V
V
K
HAA-AP
D
V
F
F
T
EFTN---------------S----------DSFCHPDG-K---DSV-------R----G------
R
--------
L
T
FT-EDEQ
P
M
V
A
H
IWGD
K
P
E
F
F
R
E
M
S
I
A
-
M
A
E
MGFQGIDINMGCPVP
N
V
A
E
RGKGS
G
L
I
L
R
P
E
V
---
A
A
Q
L
I
-
E
A
---AKA---G--G
L
P
V
S
V
K
TRIG------
Y
T
E
---
M
---
S
E
M
E
E
W
I
S
H
------
L
L
H
Q
D
I
A
N
L
S
V
H
L
R
T
R
K
E
M
S
K
V
-------
D
-
A
-
H
W
E
V
I
P
K
I
I
A
L
R
D
QIAP
Q
T
L
I
T
INGD----IPDRQ
T
G
E
E
L
A
E
K
YGVD
G
I
M
IGRGIFKNP---YAF-E--KD---
P
R
E
--------
H
T
E
K
E
L
I
G
L
L
R
L
QLD
L
Q
D
H
Y
S
E
I
I
P
-----
R
--
S
I
T
G
L
H
R
F
F
K
I
Y
IKGFPGA
N
D
L
R
V
Q
L
MNTK
S
T
D
E
V
R
E
I
L
E
T
F
E
K
EHPTLFSEQ
31
HHSearch
87.38
23%
-31
- C4 -
-
1VHN
1
?
A:
[5-309]
-----------
V
K
V
G
L
A
P
M
A
G
Y
T
D
S
A
F
R
T
L
A
F
E
W
--
G
A
D
F
A
F
S
E
M
V
S
---------------
A
----------
K
G
F
L
M
N
S
------
Q
K
T
-------
E
----
E
------
L
--------
L
-
P
Q
-
P
H
E
R
N
V
A
V
Q
I
F
G
S
E
P
N
E
L
S
E
A
A
R
I
-
L
S
E
-
K
Y
K
W
I
D
L
N
A
G
C
P
V
R
K
V
V
K
E
G
A
G
G
A
L
L
K
D
L
R
H
---
F
R
Y
I
V
-
R
E
---
L
R
K
S
--
V
--
S
G
K
F
S
V
K
T
R
L
G
------
W
E
K
-------
N
E
V
E
E
I
Y
R
I
------
L
V
E
E
G
V
D
E
V
F
I
H
T
R
T
V
V
Q
S
F
T
G
-------
R
-
A
-
E
W
K
A
L
S
V
L
E
K
-------
R
I
P
T
F
V
S
G
D
----
I
F
T
P
E
D
A
K
R
A
L
E
E
S
G
C
D
G
L
L
V
A
R
G
A
I
G
R
P
---
W
I
F
-
K
--
Q
I
---
K
D
F
L
R
SG
K
Y
S
E
P
S
R
E
E
I
L
R
T
F
E
R
H
L
E
L
L
I
K
T
K
G
E
R
K
--------
A
V
V
E
M
R
K
F
L
A
G
Y
T
K
D
L
K
G
A
R
R
F
R
E
K
V
M
K
I
E
E
V
Q
I
L
K
E
M
F
Y
N
F
I
K
E
V
E
------
8
PsiBlast_PDB
85.79
25%
-32
- C4 -
-
1VHN
1
?
A:
[9-307]
---------------
L
A
P
M
A
G
Y
T
D
S
A
F
R
T
L
A
F
E
W
G
-
A
-
D
F
A
F
S
E
M
V
S
---------------
A
----------
K
G
F
L
M
N
S
Q
-
K
---
T
E
--------------------
E
--------
L
L
P
Q
-
P
H
E
R
N
V
A
V
Q
I
F
G
S
E
P
N
E
L
S
E
A
A
R
I
-
L
S
E
K
-
Y
K
W
I
D
L
N
A
G
C
P
V
R
K
V
V
K
E
G
A
G
G
A
L
L
K
D
L
R
H
---
F
R
Y
I
V
R
E
L
---
R
K
S
---
V
--
S
G
K
F
S
V
K
T
R
L
G
------
W
-
E
---
K
---
N
E
V
E
E
I
Y
R
I
------
L
V
E
E
G
V
D
E
V
F
I
H
T
R
T
V
V
Q
S
F
T
G
-------
R
-
A
-
E
W
----
K
A
L
S
V
L
E
K
R
I
P
---
T
F
V
S
G
D
----
I
F
T
P
E
D
A
K
R
A
L
E
E
S
G
C
D
G
L
L
V
A
R
G
A
I
G
R
P
---
W
I
F
-
K
Q
I
K
D
F
L
R
S
G
K
--------
Y
S
E
P
S
R
E
E
I
L
R
---
T
F
E
R
H
L
E
L
L
I
K
T
KG
E
R
K
--
A
V
V
E
M
R
K
F
L
A
G
Y
T
K
D
L
K
G
A
R
R
F
R
E
K
V
M
K
I
E
E
V
Q
I
L
K
E
M
F
Y
N
F
I
K
E
--------
23
Fugue
80.38
23%
16
- C4 -
-
4BFA
4
DUSC_ECOLI
A:
[22-338]
---------
A
S
M
R
V
L
L
A
P
M
E
G
V
L
D
S
L
V
R
E
L
L
T
E
V
N
-
D
Y
D
L
C
I
T
E
F
V
R
---------------
V
----------
V
D
Q
L
L
P
V
K
-
V
---
F
H
R
-------
I
C
PEL
Q
------
N
--------
A
S
R
T
-
P
S
G
T
L
V
R
V
Q
L
L
G
Q
F
P
Q
W
L
A
E
N
A
A
R
-
A
V
E
L
G
S
W
G
V
D
L
N
C
G
C
P
S
K
T
V
N
G
S
G
G
G
A
T
L
L
K
D
P
E
L
---
I
Y
Q
G
A
-
K
A
---
M
R
E
A
VP
A
--
H
L
P
V
S
V
K
V
R
L
G
------
W
D
S
---
G
---
E
K
K
F
E
I
A
D
A
------
V
Q
Q
A
G
A
T
E
L
V
V
H
G
R
T
K
E
Q
G
Y
R
A
-------
E
-
H
I
D
W
Q
A
I
G
D
I
R
Q
R
-----
L
N
I
P
V
I
A
N
G
E
----
I
W
D
W
Q
S
A
Q
Q
C
M
A
I
S
G
C
D
A
V
M
I
G
R
G
A
L
N
I
P
N
L
S
R
V
V
-
K
--
Y
N
---
E
P
R
--------
M
P
W
P
E
V
V
A
L
L
Q
K
Y
T
R
L
E
K
Q
G
D
T
G
L
------
Y
--
H
V
A
R
I
K
Q
W
L
S
Y
L
R
K
E
Y
D
E
A
T
E
L
F
Q
H
V
R
V
L
N
N
S
P
D
I
A
R
A
I
Q
A
I
D
I
E
K
L
------
32
HHSearch
79.94
23%
11
- C4 -
-
4BFA
4
DUSC_ECOLI
A:
[22-336]
---------
A
S
M
R
V
L
L
A
P
M
E
G
V
L
D
S
L
V
R
E
L
L
T
E
V
N
-
D
Y
D
L
C
I
T
E
F
V
R
---------------
V
----------
V
D
Q
L
L
P
V
------
K
V
F
-------
H
----
R
I
C
PELQ
N
--------
A
S
R
T
-
P
S
G
T
L
V
R
V
Q
L
L
G
Q
F
P
Q
W
L
A
E
N
A
A
R
-
A
V
E
L
G
S
W
G
V
D
L
N
C
G
C
P
S
K
T
V
N
G
S
G
G
G
A
T
L
L
K
D
P
E
L
---
I
Y
Q
G
A
-
K
A
---
M
R
E
A
--
V
PA
H
L
P
V
S
V
K
V
R
L
G
------
W
D
S
---
G
---
E
K
K
F
E
I
A
D
A
------
V
Q
Q
A
G
A
T
E
L
V
V
H
G
R
T
K
E
Q
G
Y
R
A
E------
H
-
I
-
D
W
Q
A
I
G
D
I
R
Q
R
L
-----
N
I
P
V
I
A
N
G
E
----
I
W
D
W
Q
S
A
Q
Q
C
M
A
I
S
G
C
D
A
V
M
I
G
R
G
A
L
N
I
P
---
N
L
S
-
R
--
V
V
---
K
Y
N
EPR-----
M
P
W
P
E
V
V
A
L
L
Q
K
Y
T
R
L
E
K
Q
G
D
T
G
L
Y
--------
H
V
A
R
I
K
Q
W
L
S
Y
L
R
K
E
Y
D
E
A
T
E
L
F
Q
H
V
R
V
L
N
N
S
P
D
I
A
R
A
I
Q
A
I
D
I
E
--------
22
Fugue
79.27
22%
-33
- C4 -
-
3B0P
1
DUSAL_THET8
A:
[2-318]
---------
L
D
P
R
L
S
V
A
P
M
V
D
R
T
D
R
H
F
R
F
L
V
R
Q
V
S
-
L
G
V
R
L
Y
T
E
M
T
V
---------------
D
----------
Q
A
V
L
R
G
N
--------
R
-------
E
----
R
------
L
--------
L
A
F
R
-
P
E
E
H
P
I
A
L
Q
L
A
G
S
D
P
K
S
L
A
E
A
A
R
I
-
G
E
A
F
G
Y
D
E
I
N
L
N
L
G
C
P
S
E
K
A
Q
E
G
G
Y
G
A
C
L
L
L
D
L
A
R
---
V
R
E
I
L
-
K
A
---
M
G
E
---
A
V
-
R
V
P
V
T
V
K
M
R
L
G
------
L
E
G
KET
Y
---
R
G
L
A
Q
S
V
E
A
------
M
A
E
A
G
V
K
V
F
V
V
H
A
R
S
---
A
L
I
P
-------
P
-
L
-
R
H
D
W
V
H
R
L
K
G
D
F
----
P
Q
L
T
F
V
T
N
G
G
----
I
R
S
L
E
E
A
L
F
H
L
K
R
--
V
D
G
V
M
L
G
R
A
V
Y
E
D
P
---
F
V
L
E
E
--
A
D
---
R
R
V
--------
F
G
L
P
R
R
P
S
R
L
E
V
A
R
R
M
R
A
Y
L
E
E
E
V
L
-----
K
GT
P
P
W
A
V
L
R
H
M
L
N
L
F
R
G
R
P
K
G
R
L
W
R
R
L
L
S
E
G
R
S
L
Q
A
L
D
R
A
L
R
L
M
E
E
E
V
G
E
-----
33
HHSearch
78.59
23%
12
- C4 -
-
4YCO
1
DUSC_ECOLI
C:
[6-319]
----------
S
M
R
V
L
L
A
P
M
E
G
V
L
D
S
L
V
R
E
L
L
T
E
V
N
-
D
Y
D
L
C
I
T
E
F
V
R
---------------
V
----------
V
D
Q
L
L
P
V
------
K
V
F
-------
H
----
R
------
I
CPELQN--
A
S
R
T
-
P
S
G
T
L
V
R
V
Q
L
L
G
Q
F
P
Q
W
L
A
E
N
A
A
R
-
A
V
E
L
G
S
W
G
V
D
L
N
C
G
A
P
S
----
G
S
G
G
G
A
T
L
L
K
D
P
E
L
---
I
Y
Q
G
A
-
K
A
---
M
R
E
A--
V
PA
H
L
P
V
S
V
K
V
R
L
G
------
W
D
S
---
G
---
E
K
K
F
E
I
A
D
A
------
V
Q
Q
A
G
A
T
E
L
V
V
H
G
R
T
K
E
Q
G
Y
R
A
E------
H
-
I
-
D
W
Q
A
I
G
D
I
R
Q
R
L
-----
N
I
P
V
I
A
N
G
E
----
I
W
D
W
Q
S
A
Q
Q
C
M
A
I
S
G
C
D
A
V
M
I
G
R
G
A
L
N
I
P
---
N
L
S
-
R
--
V
V
---
K
Y
N
EPR-----
M
P
W
P
E
V
V
A
L
L
Q
K
Y
T
R
L
E
K
Q
G
D
T
G
L
Y
--------
H
V
A
R
I
K
Q
W
L
S
Y
L
R
K
E
Y
D
E
A
T
E
L
F
Q
H
V
R
V
L
N
N
S
P
D
I
A
R
A
I
Q
A
I
D
I
E
--------
35
HHSearch
73.92
21%
8
- C4 -
-
3B0P
1
DUSAL_THET8
A:
[2-318]
---------
L
D
P
R
L
S
V
A
P
M
V
D
R
T
D
R
H
F
R
F
L
V
R
Q
V
S
L
G
V
R
-
L
Y
T
E
M
T
V
---------------
D
----------
Q
A
V
L
R
G
N
------
R
E
R
-------------------
L
--------
L
A
F
R
-
P
E
E
H
P
I
A
L
Q
L
A
G
S
D
P
K
S
L
A
E
A
A
R
I
-
G
E
A
F
G
Y
D
E
I
N
L
N
L
G
C
P
S
E
K
A
Q
E
G
G
Y
G
A
C
L
L
L
D
L
A
R
---
V
R
E
I
L
-
K
A
---
M
G
E
A
--
V
--
R
V
P
V
T
V
K
M
R
L
G
------
L
E
G
---
K
ET
Y
R
G
L
A
Q
S
V
E
A
------
M
A
E
A
G
V
K
V
F
V
V
H
A
R
S
A
L
-----IP-----
P
-
L
-
R
H
D
W
V
H
R
L
K
G
D
F
----
P
Q
L
T
F
V
T
N
G
G
----
I
R
S
L
E
E
A
L
F
H
L
K
--
R
V
D
G
V
M
L
G
R
A
V
Y
E
D
P
---
F
V
L
-
E
--
E
A
---
D
R
R
VFGL----
P
R
R
P
S
R
L
E
V
A
R
R
M
R
A
Y
L
E
E
E
V
L
K
G
T
--------
P
P
W
A
V
L
R
H
M
L
N
L
F
R
G
R
P
K
G
R
L
W
R
R
L
L
S
E
G
R
S
L
Q
A
L
D
R
A
L
R
L
M
E
E
E
V
G
E
-----
36
HHSearch
72.81
21%
5
- C4 -
-
3B0U
2
DUSAL_THET8
Y:
[2-313]
---------
L
D
P
R
L
S
V
A
P
M
V
D
R
T
D
R
H
F
R
F
L
V
R
Q
V
S
L
G
V
R
-
L
Y
T
E
M
T
V
---------------
D
----------
Q
A
V
L
R
G
N
------
R
E
R
-------------------
L
--------
L
A
F
R
-
P
E
E
H
P
I
A
L
Q
L
A
G
S
D
P
K
S
L
A
E
A
A
R
I
-
G
E
A
F
G
Y
D
E
I
N
L
N
L
G
C
P
S
E
K
A
Q
E
G
G
Y
G
A
C
L
L
L
D
L
A
R
---
V
R
E
I
L
-
K
A
---
M
G
E
A--
V
--
R
V
P
V
T
V
K
M
R
L
G
------
L
E
G
---
K
ETY
R
G
L
A
Q
S
V
E
A
------
M
A
E
A
G
V
K
V
F
V
V
H
A
R
S
A
L
L
A
L
S
T
KANREIP
P
-
L
-
R
H
D
W
V
H
R
L
K
G
D
F
----
P
Q
L
T
F
V
T
N
G
G
----
I
R
S
L
E
E
A
L
F
H
L
K
--
R
V
D
G
V
M
L
G
R
A
V
Y
E
D
P
---
F
V
L
-
E
--
E
A
---
D
R
R
VFGL----
P
R
R
P
S
R
L
E
V
A
R
R
M
R
A
Y
L
E
E
E
V
L
K
G
T
--------
P
P
W
A
V
L
R
H
M
L
N
L
F
R
G
R
P
K
G
R
L
W
R
R
L
L
S
E
G
R
S
L
Q
A
L
D
R
A
L
R
L
M
E
----------
6
PsiBlast_PDB
71.29
27%
-1
- C4 -
-
4YCP
1
DUSC_ECOLI
A:
[9-237]
-------------
V
L
L
A
P
M
E
G
V
L
D
S
L
V
R
E
L
L
T
E
V
N
-
D
Y
D
L
C
I
T
E
F
V
R
---------------
V
VDQLLP
V
K
V
F
H
R
I
C
-
P
E
L
-
Q
---
N
A
S
-------
R
-----------------------
T
-
P
S
G
T
L
V
R
V
Q
L
L
G
Q
F
P
Q
W
L
A
E
N
A
A
R
-
A
V
E
L
G
S
W
G
V
D
L
N
C
G
A
P
-------
G
G
G
A
T
L
L
K
D
P
E
L
I
Y
Q
G
A
K
A
M
-
R
E
---
A
V
P
---
A
--
H
L
P
V
S
V
K
V
R
L
G
------
W
D
S
---
G
---
E
K
K
F
E
I
A
D
A
------
V
Q
Q
A
G
A
T
E
L
V
V
H
G
R
T
K
E
Q
G
Y
R
A
-------
E
H
I
-
D
W
Q
A
I
G
D
I
---
R
Q
R
L
--
N
I
P
V
I
A
N
G
E
----
I
W
D
W
Q
S
A
Q
Q
C
M
A
I
S
G
C
D
A
V
M
I
G
R
G
A
L
N
I
P
----------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
70.57
25%
-29
- C4 -
-
3B0U
3
DUSAL_THET8
X:
[4-240]
-----------
P
R
L
S
V
A
P
M
V
D
R
T
D
R
H
F
R
F
L
V
R
Q
V
S
-
L
G
V
R
L
Y
T
E
M
T
V
---------------
D
----------
Q
A
V
L
R
G
N
R
-
E
---
R
L
-----------------------------
L
A
F
R
-
P
E
E
H
P
I
A
L
Q
L
A
G
S
D
P
K
S
L
A
E
A
A
R
I
-
G
E
A
F
G
Y
D
E
I
N
L
N
L
G
C
P
S
E
K
A
Q
E
G
G
Y
G
A
C
L
L
L
D
L
A
R
---
V
R
E
I
L
-
K
A
M--
G
E
A
---
V
--
R
V
P
V
T
V
K
M
R
L
G
LEGKET
Y
R
G
---
L
---
A
Q
S
V
E
A
M
A
E
AGVKVF
V
V
H
A
R
S
A
L
L
A
L
S
T
K
A
N
R
E
I
P
P
L
-------
R
-
H
-
D
W
-----
V
H
R
L
K
G
D
F
-
P
Q
L
T
F
V
T
N
G
G
----
I
--
R
S
L
E
E
A
L
F
H
L
K
R
V
D
G
V
M
L
G
R
A
V
Y
E
D
P
---
F
V
L
-
E
--
E
A
---
D
R
-----------------------------------------------------------------------------------------------
34
HHSearch
70.23
20%
-28
- C4 -
-
4WFS
1
DUS2L_HUMAN
A:
[6-309]
-----------
H
H
L
I
L
A
P
M
V
R
V
G
T
L
P
M
R
L
L
A
L
D
Y
--
G
A
D
I
V
Y
C
E
E
L
I
---------------
D
----------
L
K
M
I
Q
C
K
R
V
V
N
EV
L
S
T
-------
V
----
D
------
F
V
A
PDDRVV
F
R
T
C
E
R
E
Q
N
R
V
V
F
Q
M
G
T
S
D
A
E
R
A
L
A
V
A
R
L
-
V
E
-
N
D
V
A
G
I
D
V
N
M
G
-------------
A
L
L
S
D
P
D
K
---
I
E
K
I
L
-
S
T
---
L
V
K
G
--
T
--
R
R
P
V
T
C
K
I
R
I
L
------
P
S
L
-------
E
D
T
L
S
L
V
K
R
------
I
E
R
T
G
I
A
A
I
A
V
H
G
R
K
R
E
E
R
P
Q
H
-------
P
-
V
-
S
C
E
V
I
K
A
I
A
D
T
L
-----
S
I
P
V
I
A
N
G
G
SHDH
I
Q
Q
Y
S
D
I
E
D
F
R
Q
A
T
A
A
S
S
V
M
V
A
R
A
A
M
W
N
P
---
S
I
F
-
L
--
K
E
---
G
L
------------
R
P
L
E
E
V
M
Q
K
Y
I
R
Y
A
V
Q
Y
D
N
-----------
H
Y
T
N
T
K
Y
C
L
C
Q
M
L
R
E
Q
L
E
-
S
P
Q
G
R
L
L
H
A
A
Q
S
S
R
E
I
C
E
A
F
G
-------------
37
HHSearch
69.97
19%
-21
- C4 -
-
4XP7
1
DUS2L_HUMAN
A:
[13-320]
------
S
L
C
Y
H
N
K
L
I
L
A
P
M
V
R
V
G
T
L
P
M
R
L
L
A
L
D
Y
--
G
A
D
I
V
Y
C
E
E
L
I
---------------
D
----------
L
K
M
I
Q
C
K
R
V
V
NEV
L
S
T
VDFVAPD
D
----
R
V-----
V
--------
F
R
T
C
E
R
E
Q
N
R
V
V
F
Q
M
G
T
S
D
A
E
R
A
L
A
V
A
R
L
-
V
E
-
N
D
V
A
G
I
D
V
N
M
G
C
P
K
Q
---------
A
L
L
S
D
P
D
K
---
I
E
K
I
L
-
S
T
---
L
V
K
G
--
T
--
R
R
P
V
T
C
K
I
R
I
L
------
P
S
L
-------
E
D
T
L
S
L
V
K
R
------
I
E
R
T
G
I
A
A
I
A
V
H
G
R
K
R
E
E
R
P
Q
H
-------
P
-
V
-
S
C
E
V
I
K
A
I
A
D
T
L
-----
S
I
P
V
I
A
N
G
G
SHDH
I
Q
Q
Y
S
D
I
E
D
F
R
Q
A
T
A
A
S
S
V
M
V
A
R
A
A
M
W
N
P
---
S
I
F
-
L
--
K
E
---
G
L
------------
R
P
L
E
E
V
M
Q
K
Y
I
R
Y
A
V
Q
Y
D
N
-----------
H
Y
T
N
T
K
Y
C
L
C
Q
M
L
R
E
Q
L
E
-
S
P
Q
G
R
L
L
H
A
A
Q
S
S
R
E
I
C
E
A
F
--------------
3
PsiBlast_PDB
69.51
25%
-47
- C4 -
-
3B0P
1
DUSAL_THET8
A:
[4-240]
-----------
P
R
L
S
V
A
P
M
V
D
R
T
D
R
H
F
R
F
L
V
R
Q
V
S
-
L
G
V
R
L
Y
T
E
M
T
V
---------------
D
----------
Q
A
V
L
R
G
N
R
-
E
---
R
L
-----------------------------
L
A
F
R
-
P
E
E
H
P
I
A
L
Q
L
A
G
S
D
P
K
S
L
A
E
A
A
R
I
-
G
E
A
F
G
Y
D
E
I
N
L
N
L
G
C
P
S
E
K
A
Q
E
G
G
Y
G
A
C
L
L
L
D
L
A
R
---
V
R
E
I
L
-
K
A
M
--
G
E
A
---
V
--
R
V
P
V
T
V
K
M
R
L
G
LEGKET
Y
R
G
---
L
---
A
Q
S
V
E
A
M
A
E
A
GVK
V
F
V
V
H
A
R
S
A
L
----------
I
P
P
L
-------
R
-
H
-
D
W
-----
V
H
R
L
K
G
D
F
-
P
Q
L
T
F
V
T
N
G
G
----
I
--
R
S
L
E
E
A
L
F
H
L
K
R
V
D
G
V
M
L
G
R
A
V
Y
E
D
P
---
F
V
L
-
E
--
E
A
---
D
R
-----------------------------------------------------------------------------------------------
9
PsiBlast_PDB
69.17
24%
-34
- C4 -
-
3B0V
1
DUSAL_THET8
C:
[25-261]
-----------
P
R
L
S
V
A
P
M
V
D
R
T
D
R
H
F
R
F
L
V
R
Q
V
S
-
L
G
V
R
L
Y
T
E
M
T
V
---------------
D
----------
Q
A
V
L
R
G
N
R
-
E
---
R
L
-----------------------------
L
A
F
R
-
P
E
E
H
P
I
A
L
Q
L
A
G
S
D
P
K
S
L
A
E
A
A
R
I
-
G
E
A
F
G
Y
D
E
I
N
L
N
L
G
C
P
S
E
K
A
Q
E
G
G
Y
G
A
C
L
L
L
D
L
A
R
---
V
R
E
I
L
-
K
A
M--
G
E
A
---
V
--
R
V
P
V
T
V
K
M
R
L
G
LEGKET
Y
R
G
---
L
---
A
Q
S
V
E
A
M
A
E
AGVKVF
V
V
H
A
R
S
A
L
L
A
L
S
T
K
A
N
R
E
I
P
P
L
-------
R
-
H
-
D
W
-----
V
H
R
L
K
G
D
F
-
P
Q
L
T
F
V
T
N
G
G
----
I
--
R
S
L
E
E
A
L
F
H
L
K
R
V
D
G
V
M
L
G
R
A
V
Y
E
D
P
---
F
V
L
-
E
--
E
A
---
D
R
-----------------------------------------------------------------------------------------------
5
PsiBlast_PDB
68.32
27%
4
- C4 -
-
4YCO
1
DUSC_ECOLI
A:
[9-237]
-------------
V
L
L
A
P
M
E
G
V
L
D
S
L
V
R
E
L
L
T
E
V
N
-
D
Y
D
L
C
I
T
E
F
V
R
---------------
V
VDQLLP
V
K
V
F
H
R
I
C
-
P
E
L
-
Q
---
N
A
S
-------
R
-----------------------
T
-
P
S
G
T
L
V
R
V
Q
L
L
G
Q
F
P
Q
W
L
A
E
N
A
A
R
-
A
V
E
L
G
S
W
G
V
D
L
N
C
G
A
P
S
----
G
S
G
G
G
A
T
L
L
K
D
P
E
L
I
Y
Q
G
A
K
A
M
-
R
E
---
A
V
P
---
A
--
H
L
P
V
S
V
K
V
R
L
G
------
W
D
S
---
G
---
E
K
K
F
E
I
A
D
A
------
V
Q
Q
A
G
A
T
E
L
V
V
H
G
R
T
K
E
Q
G
Y
R
A
-------
E
H
I
-
D
W
Q
A
I
G
D
I
---
R
Q
R
L
--
N
I
P
V
I
A
N
G
E
----
I
W
D
W
Q
S
A
Q
Q
C
M
A
I
S
G
C
D
A
V
M
I
G
R
G
A
L
N
I
P
----------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
68.07
23%
5
- C4 -
-
4WFS
1
DUS2L_HUMAN
A:
[8-273]
-------------
L
I
L
A
P
M
V
R
V
G
T
L
P
M
R
L
L
A
L
D
Y
G
-
A
D
I
V
Y
C
E
E
L
I
D
L
K
M
I
Q
C
K
R
V
V
N
EVLS
T
----------
V
D
F
V
A
P
D
D
-
R
---
V
V
F
-------
R
----
T
------------------
C
-
E
R
E
Q
N
R
V
V
F
Q
M
G
T
S
-
D
A
E
R
A
L
A
V
A
R
L
V
E
N
D
V
A
G
I
D
V
N
M
G
-------------
A
L
L
S
D
P
D
K
---
I
E
K
I
L
-
S
T
L
--
V
K
G
---
T
--
R
R
P
V
T
C
K
I
R
I
-------
L
P
S
---
L
---
E
D
T
L
S
L
V
K
R
------
I
E
R
T
G
I
A
A
I
A
V
H
G
R
K
R
E
E
R
P
Q
H
-------
P
-
V
-
S
C
E
V
I
K
---
A
I
A
D
T
L
S
--
I
P
V
I
A
N
G
G
SHDH
I
Q
Q
Y
S
D
I
E
D
F
R
Q
A
T
A
A
S
S
V
M
V
A
R
A
A
M
W
N
P
---
S
I
F
-
L
--
K
E
---
G
L
R
--------
P
L
E
E
V
M
Q
K
Y
I
R
Y
A
V
Q
Y
D
N
H
Y
T
-----------------------------------------------------------------
2
PsiBlast_PDB
67.40
27%
11
- C4 -
-
4BFA
4
DUSC_ECOLI
A:
[26-254]
-------------
V
L
L
A
P
M
E
G
V
L
D
S
L
V
R
E
L
L
T
E
V
N
-
D
Y
D
L
C
I
T
E
F
V
R
---------------
V
VDQLLP
V
K
V
F
H
R
I
C
-
P
E
L
-
Q
---
N
A
S
-------
R
-----------------------
T
-
P
S
G
T
L
V
R
V
Q
L
L
G
Q
F
P
Q
W
L
A
E
N
A
A
R
-
A
V
E
L
G
S
W
G
V
D
L
N
C
G
C
P
S
K
T
V
N
G
S
G
G
G
A
T
L
L
K
D
P
E
L
I
Y
Q
G
A
K
A
M
-
R
E
---
A
V
P
---
A
--
H
L
P
V
S
V
K
V
R
L
G
------
W
D
S
---
G
---
E
K
K
F
E
I
A
D
A
------
V
Q
Q
A
G
A
T
E
L
V
V
H
G
R
T
K
E
Q
G
Y
R
A
-------
E
H
I
-
D
W
Q
A
I
G
D
I
---
R
Q
R
L
--
N
I
P
V
I
A
N
G
E
----
I
W
D
W
Q
S
A
Q
Q
C
M
A
I
S
G
C
D
A
V
M
I
G
R
G
A
L
N
I
P
----------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
66.35
27%
9
- C4 -
-
3W9Z
1
DUSC_ECOLI
A:
[3-242]
-------------
V
L
L
A
P
M
E
G
V
L
D
S
L
V
R
E
L
L
T
E
V
N
-
D
Y
D
L
C
I
T
E
F
V
R
---------------
V
VDQLLP
V
K
V
F
H
R
I
C
-
P
E
L
-
Q
---
N
A
S
-------
R
-----------------------
T
-
P
S
G
T
L
V
R
V
Q
L
L
G
Q
F
P
Q
W
L
A
E
N
A
A
R
-
A
V
E
L
G
S
W
G
V
D
L
N
C
G
C
-------------
L
L
K
D
P
E
L
I
Y
Q
G
A
K
A
M
-
R
E
---
A
V
P
---
A
--
H
L
P
V
S
V
K
V
R
L
G
------
W
D
S
---
G
---
E
K
K
F
E
I
A
D
A
------
V
Q
Q
A
G
A
T
E
L
V
V
H
G
R
T
K
E
Q
G
Y
R
A
-------
E
H
I
-
D
W
Q
A
I
G
D
I
---
R
Q
R
L
--
N
I
P
V
I
A
N
G
E
----
I
W
D
W
Q
S
A
Q
Q
C
M
A
I
S
G
C
D
A
V
M
I
G
R
G
A
L
N
I
P
----------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
65.10
27%
16
- C4 -
-
4BF9
1
DUSC_ECOLI
A:
[26-254]
-------------
V
L
L
A
P
M
E
G
V
L
D
S
L
V
R
E
L
L
T
E
V
N
-
D
Y
D
L
C
I
T
E
F
V
R
---------------
V
VDQLLP
V
K
V
F
H
R
I
C
-
P
E
L
-
Q
---
N
A
S
-------
R
-----------------------
T
-
P
S
G
T
L
V
R
V
Q
L
L
G
Q
F
P
Q
W
L
A
E
N
A
A
R
-
A
V
E
L
G
S
W
G
V
D
L
N
C
G
C
P
S
K
T
V
N
G
S
G
G
G
A
T
L
L
K
D
P
E
L
---
I
Y
Q
G
A
-
K
A
M
R
E
A
V
P
---
A
--
H
L
P
V
S
V
K
V
R
L
G
------
W
D
S
---
G
---
E
K
K
F
E
I
A
D
A
------
V
Q
Q
A
G
A
T
E
L
V
V
H
G
R
T
K
E
Q
G
Y
R
A
-------
E
H
I
-
D
W
Q
A
I
G
D
I
---
R
Q
R
L
--
N
I
P
V
I
A
N
G
E
----
I
W
D
W
Q
S
A
Q
Q
C
M
A
I
S
G
C
D
A
V
M
I
G
R
G
A
L
N
I
P
----------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
55.47
24%
4
- C4 -
-
4XP7
1
DUS2L_HUMAN
A:
[63-285]
------------------------------------------
N
E
V
L
S
---------------
T
----------
V
D
F
V
A
P
D
D
-
R
---
V
V
F
-------
R
----
T
------------------
C
-
E
R
E
Q
N
R
V
V
F
Q
M
G
T
S
-
D
A
E
R
A
L
A
V
A
R
L
V
E
N
D
V
A
G
I
D
V
N
M
G
C
P
K
Q
---------
A
L
L
S
D
P
D
K
---
I
E
K
I
L
-
S
T
L
--
V
K
G
---
T
--
R
R
P
V
T
C
K
I
R
I
-------
L
P
S
---
L
---
E
D
T
L
S
L
V
K
R
------
I
E
R
T
G
I
A
A
I
A
V
H
G
R
K
R
E
E
R
P
Q
H
-------
P
-
V
-
S
C
E
V
I
K
---
A
I
A
D
T
L
S
--
I
P
V
I
A
N
G
G
SHDH
I
Q
Q
Y
S
D
I
E
D
F
R
Q
A
T
A
A
S
S
V
M
V
A
R
A
A
M
W
N
P
---
S
I
F
-
L
--
K
E
---
G
L
R
--------
P
L
E
E
V
M
Q
K
Y
I
R
Y
A
V
Q
Y
D
N
H
Y
T
-----------------------------------------------------------------