@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo1630: (2016-03-27 )
MTFLEEILAQKEVEVAKMPLEQVAEKRKTYSFYEFLKANTNTMQLIAEVKRASPSKGEINMGVNPVLQAKSYQAAGAGMISVLTDPVFFKGSIEDLREVAKNVGIPVLCKDFIISEKQLIRARNAGATVVLLIISALTEEKLITLFEQALALDLEVLVEVHDQEELAVAQKIGAQLIGVNNRNLHTFEVDIAVSERLASDFSSDACFISESGFRTAEDVARVSQKYDAVLVGEALMREATPEVAAKSLKVTR
Atome Classification :
(21 SA)
-.........10....----....----20--..-...--...------30.--......-----.40........50........60........70........80........90........100.-......110.......120...-....130.......140.......150.......160........170........180.....--..190...---....200---.......210..-.....220..-.-....230.......240--........250
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-M
T
F
L
E
E
I
L
A
Q
K
E
V
E
V
----
A
KM
P
----
L
E
--
Q
V
-
A
E
K
--RK
T
------
Y
S
F
--
Y
E
F
L
K
A-----NT
N
T
M
Q
L
I
A
E
V
K
RASPSKG
E
I
NMGVNP
V
L
QAKSYQAAGA
G
M
I
S
VLTD
P
V
F
FKG
S
I
E
D
L
R
E
V
A
K
NV-GI
P
V
L
C
K
D
F
II
S
E
K
Q
L
I
R
ARNA-GAT
V
V
L
L
I
I
S
A
L
T
E
E
K
L
I
T
L
F
E
Q
A
L
A
L
D
L
E
V
L
V
E
VH-
D
Q
E
E
L
A
V
A
Q
K
-I
G
A
Q
L
I
GVNNR
N
L
H
T
F
--
E
V
D
I
A
V
S
E
---
R
L
A
S
DFS---SD
A
C
F
ISESGFR-
T
A
E
D
V
A
R
V
S
Q
-K-Y
D
A
V
L
V
G
E
A
L
M
R
EA
T
P
---
E
V
A
A
K
SLKVTR
58
HHSearch
91.75
38%
-110
- C3 -
3QJA
1
TRPC_MYCTU
A:
[4-260]
-
A
T
V
L
D
S
I
L
E
G
V
R
A
D
V
----
A
A
R
E
A
S
VS
L
S
--
E
I
-
K
A
A
A
A
A
A
P
------
P
P
L
D
V
M
A
A
L
R
-------
E
P
G
I
G
V
I
A
E
V
K
-------------
D
P
A
K
L
A
Q
A
Y
Q
D
G
G
A
R
I
V
S
V
V
T
E
Q
R
R
F
Q
G
S
L
D
D
L
D
A
V
R
A
S
V
-
S
I
P
V
L
R
K
D
F
V
V
Q
P
Y
Q
I
H
E
A
R
A
H
-
G
A
D
M
L
L
L
I
V
A
A
L
E
Q
S
V
L
V
S
M
L
D
R
T
E
S
L
G
M
T
A
L
V
E
V
H
-
T
E
Q
E
A
D
R
A
L
K
-
A
G
A
K
V
I
G
V
N
A
R
D
L
M
T
L
--
D
V
D
R
D
C
F
A
---
R
I
A
P
G
L
P
---
S
S
V
I
R
I
A
E
S
G
V
R
-
G
T
A
D
L
L
A
Y
A
G
A
G
-
A
D
A
V
L
V
G
E
G
L
V
T
S
G
D
P
---
R
A
A
V
A
D
L
V
T
--
45
Fugue
91.67
35%
-112
- C3 -
1PII
1
?
?:
[1-255]
M
Q
T
V
L
A
K
I
V
A
D
K
A
I
W
V
----
E
A
R
K
----
Q
Q
--
Q
P
-
L
A
S
--
F
Q
N
EVQPST
R
H
F
--
Y
D
A
L
Q
G
-----
A
R
--
T
A
F
I
L
E
C
K
K
A
S
P
S
K
G
V
I
R
D
D
F
D
P
A
R
I
A
A
I
Y
K
H
-
Y
A
S
A
I
S
V
L
T
D
E
K
Y
F
Q
G
S
F
N
F
L
P
I
V
S
Q
I
A
P-
Q
P
I
L
C
K
D
F
I
I
D
P
Y
Q
I
Y
L
A
R
-
Y
Y
Q
A
D
A
C
L
L
M
L
S
V
L
D
D
D
Q
Y
R
Q
L
A
A
V
A
H
S
L
E
M
G
V
L
T
E
V
S
N-
E
E
E
Q
E
R
A
I
A
-
L
G
A
K
V
V
G
I
N
N
R
D
L
R
D
L
SI--
D
L
N
R
T
R
---
E
L
A
P
K
L
G
---
H
N
V
T
V
I
S
E
S
G
I
N
-
T
Y
A
Q
V
R
E
L
S
H
--F
A
N
G
F
L
I
G
S
A
L
M
A
H
D
--D
L
H
A
A
V
R
R
V
L
L
G
--
56
HHSearch
90.29
39%
-101
* C3 *
1VC4
6
?
A:
[10-253]
--
G
V
L
G
E
I
A
R
K
R
A
S
E
V
----
A
P
Y
P
---------
L
-
P
E
P
--
P
-
S
------
V
P
S
F
-
K
E
A
L
L
-------
R
P
G
L
S
V
I
A
E
V
K
R
Q
S
P
S
E
G
L
I
R
E
-
V
D
P
V
E
A
A
L
A
Y
A
R
G
G
A
R
A
V
S
V
L
T
E
P
H
R
F
G
G
S
L
L
D
L
K
R
V
R
E
A
V
-
D
L
P
L
L
R
K
D
F
V
V
D
P
F
M
L
E
E
A
R
A
F
-
G
A
S
A
A
L
L
I
V
A
L
L
G
E
-
L
T
G
A
Y
L
E
E
A
R
R
L
G
L
E
A
L
V
E
V
H
-
T
E
R
E
L
E
I
A
L
E
-
A
G
A
E
V
L
G
I
N
N
R
D
L
A
T
L
--
H
I
N
L
E
T
A
P
---
R
L
G
R
L
A
R
K
R
G
F
G
G
V
L
V
A
E
S
G
Y
S
-
R
K
E
E
L
K
A
L
E
G
-
L
-
F
D
A
V
L
I
G
T
S
L
M
R
A
P
D
L
---
E
A
A
L
R
E
L
V
---
6
PsiBlast_PDB
90.29
39%
-105
- C3 -
1VC4
6
?
A:
[12-252]
----
L
G
E
I
A
R
K
R
A
S
E
V
----
A
P
Y
P
----
L
------
P
E
P
--
P
S
V
------
P
S
F
--
K
E
A
L
L
-------
R
P
G
L
S
V
I
A
E
V
K
R
Q
S
P
S
E
G
L
I
R
E
-
V
D
P
V
E
A
A
L
A
Y
A
R
G
G
A
R
A
V
S
V
L
T
E
P
H
R
F
G
G
S
L
L
D
L
K
R
V
R
E
A
V
-
D
L
P
L
L
R
K
D
F
V
V
D
P
F
M
L
E
E
A
R
A
F
-
G
A
S
A
A
L
L
I
V
-
A
L
L
G
E
L
T
G
A
Y
L
E
E
A
R
R
L
G
L
E
A
L
V
E
V
H
-
T
E
R
E
L
E
I
A
L
E
-
A
G
A
E
V
L
G
I
N
N
R
D
L
A
T
L
--
H
I
N
L
E
T
A
P
R
L
G
R
L
A
R
K
R
G
---
F
G
G
V
L
V
A
E
S
G
Y
S
-
R
K
E
E
L
K
A
L
E
G
-
L
-
F
D
A
V
L
I
G
T
S
L
M
R
A
P
D
L
---
E
A
A
L
R
E
L
----
55
HHSearch
90.28
38%
-101
- C3 -
3TSM
3
TRPC_BRUA2
A:
[8-267]
--
D
I
L
R
K
I
E
A
Y
K
R
E
E
I
----
A
A
A
K
A
R
L
A
L
D
--
E
L
-
K
A
R
T
R
D
Q
S
------
A
P
R
G
F
L
K
A
L
E
A
K
R
---
A
A
G
Q
F
A
L
I
A
E
I
K
K
A
S
P
S
K
G
L
I
R
P
D
F
D
P
P
A
L
A
K
A
Y
E
E
G
G
A
A
C
L
S
V
L
T
D
T
P
S
F
Q
G
A
P
E
F
L
T
A
A
R
Q
A
C
-
S
L
P
A
L
R
K
D
F
L
F
D
P
Y
Q
V
Y
E
A
R
S
W
-
G
A
D
C
I
L
I
I
M
A
S
V
D
D
D
L
A
K
E
L
E
D
T
A
F
A
L
G
M
D
A
L
I
E
V
H
-
D
E
A
E
M
E
R
A
L
K
-
L
S
S
R
L
L
G
V
N
N
R
N
L
R
S
F
--
E
V
N
L
A
V
S
E
---
R
L
A
K
M
A
P
---
S
D
R
L
L
V
G
E
S
G
I
F
-
T
H
E
D
C
L
R
L
E
K
S
G
-
I
G
T
F
L
I
G
E
S
L
M
R
Q
H
D
V
---
A
A
A
T
R
A
L
L
T
--
22
PsiBlast_CBE
88.73
39%
-100
- C3 -
1VC4
8
?
B:
[12-252]
----
L
G
E
I
A
R
K
R
A
S
E
V
----
A
P
Y
P
----
L
------
P
E
P
--
P
S
V
------
P
S
F
--
K
E
A
L
L
-------
R
P
G
L
S
V
I
A
E
V
K
R
Q
S
P
S
E
G
L
I
R
E
-
V
D
P
V
E
A
A
L
A
Y
A
R
G
G
A
R
A
V
S
V
L
T
E
P
H
R
F
G
G
S
L
L
D
L
K
R
V
R
E
A
V
-
D
L
P
L
L
R
K
D
F
V
V
D
P
F
M
L
E
E
A
R
A
F
-
G
A
S
A
A
L
L
I
V
-
A
L
L
G
E
L
T
G
A
Y
L
E
E
A
R
R
L
G
L
E
A
L
V
E
V
H
-
T
E
R
E
L
E
I
A
L
E
-
A
G
A
E
V
L
G
I
N
N
R
D
L
A
T
L
--
H
I
N
L
E
T
A
P
RLG
R
L
A
R
K
R
G
---
F
G
G
V
L
V
A
E
S
G
Y
S
-
R
K
E
E
L
K
A
L
E
G
-
L
-
F
D
A
V
L
I
G
T
S
L
M
R
A
P
D
L
---
E
A
A
L
R
E
L
----
57
HHSearch
88.68
34%
-103
- C3 -
1PII
1
TRPC_ECOLI
A:
[2-252]
-
Q
T
V
L
A
K
I
V
A
D
K
A
I
W
V
----
E
A
R
K
Q
Q
QP
L
A
--
S
F
-
Q
N
E
--
V
Q
P
------
S
T
R
H
F
Y
D
A
L
Q
-------
G
A
R
T
A
F
I
L
E
C
K
K
A
S
P
S
K
G
V
I
R
D
D
F
D
P
A
R
I
A
A
I
Y
K
-
H
Y
A
S
A
I
S
V
L
T
D
E
K
Y
F
Q
G
S
F
N
F
L
P
I
V
S
Q
I
A
-
P
Q
P
I
L
C
K
D
F
I
I
D
P
Y
Q
I
Y
L
A
R
Y
Y
-
Q
A
D
A
C
L
L
M
L
S
V
L
D
D
D
Q
Y
R
Q
L
A
A
V
A
H
S
L
E
M
G
V
L
T
E
V
S
-
N
E
E
E
Q
E
R
A
I
A
-
L
G
A
K
V
V
G
I
N
N
R
D
L
R
D
L
--
S
I
D
L
N
R
T
R
---
E
L
A
P
K
L
G
---
H
N
V
T
V
I
S
E
S
G
I
N
-
T
Y
A
Q
V
R
E
L
S
H
-
F
-
A
N
G
F
L
I
G
S
A
L
M
A
H
D
D
L
---
H
A
A
V
R
R
V
----
14
PsiBlast_PDB
88.63
36%
-107
- C3 -
1PII
1
TRPC_ECOLI
A:
[3-240]
--
T
V
L
A
K
I
V
A
D
K
A
I
W
V
E
A
R
K
Q
Q
Q
P
----
L
A
SF
Q
N
-
E
V
Q
--
P
S
T
------
R
H
F
--
Y
D
A
L
Q
G
-----
A
R
T
A
--
F
I
L
E
C
K
K
A
S
P
S
K
G
V
I
R
D
D
F
D
P
A
R
I
A
A
I
Y
K
H
Y
-
A
S
A
I
S
V
L
T
D
E
K
Y
F
Q
G
S
F
N
F
L
P
I
V
S
Q
I
A
-
P
Q
P
I
L
C
K
D
F
I
I
D
P
Y
Q
I
Y
L
A
R
Y
Y
-
Q
A
D
A
C
L
L
M
L
S
V
L
D
D
D
Q
Y
R
Q
L
A
A
V
A
H
S
L
E
M
G
V
L
T
E
V
S
-
N
E
E
E
Q
E
R
A
I
A
-
L
G
A
K
V
V
G
I
N
N
R
D
L
R
D
L
--
S
I
D
L
N
R
T
R
---
E
L
A
P
K
L
G
---
H
N
V
T
V
I
S
E
S
G
I
N
-
T
Y
A
Q
V
R
E
L
S
H
-
F
-
A
N
G
F
L
I
G
S
A
L
M
-------------------
1
PsiBlast_PDB
87.16
39%
-104
- C3 -
3TSM
2
TRPC_BRUA2
A:
[19-265]
-----
E
E
I
A
A
A
K
--------
A
R
L
A
----
L
D
--
E
L
K
A
R
T
--
R
D
Q
------
S
A
P
--
R
G
F
L
K
A
L
E
A
K
R
A
A
G
Q
F
A
L
I
A
E
I
K
K
A
S
P
S
K
G
L
I
R
P
D
F
D
P
P
A
L
A
K
A
Y
E
E
G
G
A
A
C
L
S
V
L
T
D
T
P
S
F
Q
G
A
P
E
F
L
T
A
A
R
Q
A
C
-
S
L
P
A
L
R
K
D
F
L
F
D
P
Y
Q
V
Y
E
A
R
S
W
-
G
A
D
C
I
L
I
I
M
A
S
V
D
D
D
L
A
K
E
L
E
D
T
A
F
A
L
G
M
D
A
L
I
E
V
H
-
D
E
A
E
M
E
R
A
L
K
-
L
S
S
R
L
L
G
V
N
N
R
N
L
R
S
F
--
E
V
N
L
A
V
S
E
---
R
L
A
K
M
A
P
---
S
D
R
L
L
V
G
E
S
G
I
F
-
T
H
E
D
C
L
R
L
E
K
-
S
G
I
G
T
F
L
I
G
E
S
L
M
R
Q
H
D
V
---
A
A
A
T
R
A
L
----
21
PsiBlast_CBE
87.07
39%
-100
- C3 -
3TSM
5
TRPC_BRUA2
B:
[19-265]
-----
E
E
I
A
A
A
K
--------
A
R
L
A
----
L
D
--
E
L
K
A
R
T
--
R
D
Q
------
S
A
P
--
R
G
F
L
K
A
L
E
A
K
R
A
A
G
Q
F
A
L
I
A
E
I
K
K
A
S
P
S
K
G
L
I
R
P
D
F
D
P
P
A
L
A
K
A
Y
E
E
G
G
A
A
C
L
S
V
L
T
D
T
P
S
F
Q
G
A
P
E
F
L
T
A
A
R
Q
A
C
-
S
L
P
A
L
R
K
D
F
L
F
D
P
Y
Q
V
Y
E
A
R
S
W
-
G
A
D
C
I
L
I
I
M
A
S
V
D
D
D
L
A
K
E
L
E
D
T
A
F
A
L
G
M
D
A
L
I
E
V
H
-
D
E
A
E
M
E
R
A
L
K
-
L
S
S
R
L
L
G
V
N
N
R
N
L
R
S
F
--
E
V
N
L
A
V
S
E
---
R
L
A
K
M
A
P
---
S
D
R
L
L
V
G
E
S
G
I
F
-
T
H
E
D
C
L
R
L
E
K
-
S
G
I
G
T
F
L
I
G
E
S
L
M
R
Q
H
D
V
---
A
A
A
T
R
A
L
----
3
PsiBlast_PDB
84.20
42%
-92
- C3 -
3T55
3
TRPC_MYCTU
A:
[52-258]
---------------------------------------------------------------------
I
G
V
I
A
E
V
K
R
A
S
P
S
A
G
A
L
A
T
I
A
D
P
A
K
L
A
Q
A
Y
Q
D
G
G
A
R
I
V
S
V
V
T
E
Q
R
R
F
Q
G
S
L
D
D
L
D
A
V
R
A
S
V
-
S
I
P
V
L
R
K
D
F
V
V
Q
P
Y
Q
I
H
E
A
R
A
H
-
G
A
D
M
L
L
L
I
V
A
A
L
E
Q
S
V
L
V
S
M
L
D
R
T
E
S
L
G
M
T
A
L
V
E
V
H
-
T
E
Q
E
A
D
R
A
L
K
-
A
G
A
K
V
I
G
V
N
A
R
D
L
M
T
L
--
D
V
D
R
D
C
F
A
---
R
I
A
P
G
L
P
---
S
S
V
I
R
I
A
E
S
G
V
R
G
T
A
D
L
L
A
Y
A
G
A
-
G
-
A
D
A
V
L
V
G
E
G
L
V
T
S
G
D
P
---
R
A
A
V
A
D
L
----
9
PsiBlast_PDB
83.80
38%
-107
- C3 -
1A53
1
TRPC_SULSO
A:
[38-240]
-------------------------------------------------------
E
F
N
K
R
-----
N
I
T
A
--
I
I
A
E
Y
K
R
K
S
P
S
G
--
L
D
V
E
R
D
P
I
E
Y
S
K
F
M
E
R
Y
A
V
G
L
-
S
I
L
T
E
E
K
Y
F
N
G
S
Y
E
T
L
R
K
I
A
S
S
V
-
S
I
P
I
L
M
K
D
F
I
V
K
E
S
Q
I
D
D
A
Y
N
L
-
G
A
D
T
V
L
L
I
V
K
I
L
T
E
R
E
L
E
S
L
L
E
Y
A
R
S
Y
G
M
E
P
L
I
E
I
N
-
D
E
N
D
L
D
I
A
L
R
-
I
G
A
R
F
I
G
I
N
S
R
D
L
E
T
L
--
E
I
N
K
E
N
Q
R
---
K
L
I
S
M
I
P
---
S
N
V
V
K
V
A
E
S
G
I
S
-
E
R
N
E
I
E
E
L
R
K
L
G
-
V
N
A
F
L
I
G
S
S
L
M
R
--
N
P
---
E
----------
12
PsiBlast_PDB
83.51
38%
-104
- C3 -
1JUL
1
TRPC_SULSO
A:
[39-241]
-------------------------------------------------------
E
F
N
K
R
-----
N
I
T
A
--
I
I
A
E
Y
K
R
K
S
P
S
G
--
L
D
V
E
R
D
P
I
E
Y
S
K
F
M
E
R
Y
A
V
G
L
-
S
I
L
T
E
E
K
Y
F
N
G
S
Y
E
T
L
R
K
I
A
S
S
V
-
S
I
P
I
L
M
K
D
F
I
V
K
E
S
Q
I
D
D
A
Y
N
L
-
G
A
D
T
V
L
L
I
V
K
I
L
T
E
R
E
L
E
S
L
L
E
Y
A
R
S
Y
G
M
E
P
L
I
E
I
N
-
D
E
N
D
L
D
I
A
L
R
-
I
G
A
R
F
I
G
I
N
S
R
D
L
E
T
L
--
E
I
N
K
E
N
Q
R
---
K
L
I
S
M
I
P
---
S
N
V
V
K
V
A
E
S
G
I
S
-
E
R
N
E
I
E
E
L
R
K
L
G
-
V
N
A
F
L
I
G
S
S
L
M
R
--
N
P
---
E
----------
2
PsiBlast_PDB
82.88
42%
-92
- C3 -
3T44
2
TRPC_MYCTU
A:
[52-258]
---------------------------------------------------------------------
I
G
V
I
A
E
V
K
R
A
S
P
S
A
G
A
L
A
T
I
A
D
P
A
K
L
A
Q
A
Y
Q
D
G
G
A
R
I
V
S
V
V
T
E
Q
R
R
F
Q
G
S
L
D
D
L
D
A
V
R
A
S
V
-
S
I
P
V
L
R
K
D
F
V
V
Q
P
Y
Q
I
H
E
A
R
A
H
-
G
A
D
M
L
L
L
I
V
A
A
L
E
Q
S
V
L
V
S
M
L
D
R
T
E
S
L
G
M
T
A
L
V
E
V
H
-
T
E
Q
E
A
D
R
A
L
K
-
A
G
A
K
V
I
G
V
N
A
R
D
L
M
T
L
--
D
V
D
R
D
C
F
A
---
R
I
A
P
G
L
P
---
S
S
V
I
R
I
A
E
S
G
V
R
G
T
A
D
L
L
A
Y
A
G
A
-
G
-
A
D
A
V
L
V
G
E
G
L
V
T
S
G
D
P
---
R
A
A
V
A
D
L
----
5
PsiBlast_PDB
82.49
42%
-96
- C3 -
4FB7
1
TRPC_MYCTU
A:
[55-261]
---------------------------------------------------------------------
I
G
V
I
A
E
V
K
R
A
S
P
S
A
G
A
L
A
T
I
A
D
P
A
K
L
A
Q
A
Y
Q
D
G
G
A
R
I
V
S
V
V
T
E
Q
R
R
F
Q
G
S
L
D
D
L
D
A
V
R
A
S
V
-
S
I
P
V
L
R
K
D
F
V
V
Q
P
Y
Q
I
H
E
A
R
A
H
-
G
A
D
M
L
L
L
I
V
A
A
L
E
Q
S
V
L
V
S
M
L
D
R
T
E
S
L
G
M
T
A
L
V
E
V
H
-
T
E
Q
E
A
D
R
A
L
K
-
A
G
A
K
V
I
G
V
N
A
R
D
L
M
T
L
--
D
V
D
R
D
C
F
A
---
R
I
A
P
G
L
P
---
S
S
V
I
R
I
A
E
S
G
V
R
G
T
A
D
L
L
A
Y
A
G
A
-
G
-
A
D
A
V
L
V
G
E
G
L
V
T
S
G
D
P
---
R
A
A
V
A
D
L
----
54
HHSearch
82.42
31%
-96
- C3 -
1I4N
1
TRPC_THEMA
A:
[2-248]
---
R
L
W
E
I
V
E
A
K
K
K
D
I
----
L
E
I
D
----
G
E
--
N
L
-
I
V
Q
--
R
-
R
------
N
H
R
F
-
L
E
V
L
S
G
------
K
E
R
V
K
I
I
A
E
F
K
K
A
S
P
S
A
G
D
I
N
A
D
A
S
L
E
D
F
I
R
M
Y
D
E
-
L
A
D
A
I
S
I
L
T
E
K
H
Y
F
K
G
D
P
A
F
V
R
A
A
R
N
L
T
-
C
R
P
I
L
A
K
D
F
Y
I
D
T
V
Q
V
K
L
A
S
S
V
-
G
A
D
A
I
L
I
I
A
R
I
L
T
A
E
Q
I
K
E
I
Y
E
A
A
E
E
L
G
M
D
S
L
V
E
V
H
-
S
R
E
D
L
E
K
V
F
S
V
I
R
P
K
I
I
G
I
N
T
R
D
L
D
T
F
--
E
I
K
K
N
V
L
W
---
E
L
L
P
L
V
P
---
D
D
T
V
V
V
A
E
S
G
I
K
-
D
P
R
E
L
K
D
L
R
G
-
K
-
V
N
A
V
L
V
G
T
S
I
M
K
A
E
N
P
---
R
R
F
L
E
E
M
R
A
--
7
PsiBlast_PDB
82.29
38%
-107
- C3 -
1LBF
1
TRPC_SULSO
A:
[38-240]
-------------------------------------------------------
E
F
N
K
R
-----
N
I
T
A
--
I
I
A
E
Y
K
R
K
S
P
S
G
--
L
D
V
E
R
D
P
I
E
Y
S
K
F
M
E
R
Y
A
V
G
L
-
S
I
L
T
E
E
K
Y
F
N
G
S
Y
E
T
L
R
K
I
A
S
S
V
-
S
I
P
I
L
M
K
D
F
I
V
K
E
S
Q
I
D
D
A
Y
N
L
-
G
A
D
T
V
L
L
I
V
K
I
L
T
E
R
E
L
E
S
L
L
E
Y
A
R
S
Y
G
M
E
P
L
I
E
I
N
-
D
E
N
D
L
D
I
A
L
R
-
I
G
A
R
F
I
G
I
N
S
R
D
L
E
T
L
--
E
I
N
K
E
N
Q
R
---
K
L
I
S
M
I
P
---
S
N
V
V
K
V
A
E
S
G
I
S
-
E
R
N
E
I
E
E
L
R
K
L
G
-
V
N
A
F
L
I
G
S
S
L
M
R
--
N
P
---
E
----------
4
PsiBlast_PDB
82.19
42%
-95
- C3 -
3T78
5
TRPC_MYCTU
A:
[52-258]
---------------------------------------------------------------------
I
G
V
I
A
E
V
K
R
A
S
P
S
A
G
A
L
A
T
I
A
D
P
A
K
L
A
Q
A
Y
Q
D
G
G
A
R
I
V
S
V
V
T
E
Q
R
R
F
Q
G
S
L
D
D
L
D
A
V
R
A
S
V
-
S
I
P
V
L
R
K
D
F
V
V
Q
P
Y
Q
I
H
E
A
R
A
H
-
G
A
D
M
L
L
L
I
V
A
A
L
E
Q
S
V
L
V
S
M
L
D
R
T
E
S
L
G
M
T
A
L
V
E
V
H
-
T
E
Q
E
A
D
R
A
L
K
-
A
G
A
K
V
I
G
V
N
A
R
D
L
M
T
L
----
D
R
D
C
F
A
---
R
I
A
P
G
L
P
---
S
S
V
I
R
I
A
E
S
G
V
R
G
T
A
D
L
L
A
Y
A
G
A
-
G
-
A
D
A
V
L
V
G
E
G
L
V
T
S
G
D
P
---
R
A
A
V
A
D
L
----
10
PsiBlast_PDB
81.53
38%
-107
- C3 -
1IGS
1
TRPC_SULSO
A:
[39-241]
-------------------------------------------------------
E
F
N
K
R
-----
N
I
T
A
--
I
I
A
E
Y
K
R
K
S
P
S
G
--
L
D
V
E
R
D
P
I
E
Y
S
K
F
M
E
R
Y
A
V
G
L
-
S
I
L
T
E
E
K
Y
F
N
G
S
Y
E
T
L
R
K
I
A
S
S
V
-
S
I
P
I
L
M
K
D
F
I
V
K
E
S
Q
I
D
D
A
Y
N
L
-
G
A
D
T
V
L
L
I
V
K
I
L
T
E
R
E
L
E
S
L
L
E
Y
A
R
S
Y
G
M
E
P
L
I
E
I
N
-
D
E
N
D
L
D
I
A
L
R
-
I
G
A
R
F
I
G
I
N
S
R
D
L
E
T
L
--
E
I
N
K
E
N
Q
R
---
K
L
I
S
M
I
P
---
S
N
V
V
K
V
A
E
S
G
I
S
-
E
R
N
E
I
E
E
L
R
K
L
G
-
V
N
A
F
L
I
G
S
S
L
M
R
--
N
P
---
E
----------
8
PsiBlast_PDB
80.97
38%
-108
- C3 -
1LBL
1
TRPC_SULSO
A:
[38-240]
-------------------------------------------------------
E
F
N
K
R
-----
N
I
T
A
--
I
I
A
E
Y
K
R
K
S
P
S
G
--
L
D
V
E
R
D
P
I
E
Y
S
K
F
M
E
R
Y
A
V
G
L
-
S
I
L
T
E
E
K
Y
F
N
G
S
Y
E
T
L
R
K
I
A
S
S
V
-
S
I
P
I
L
M
K
D
F
I
V
K
E
S
Q
I
D
D
A
Y
N
L
-
G
A
D
T
V
L
L
I
V
K
I
L
T
E
R
E
L
E
S
L
L
E
Y
A
R
S
Y
G
M
E
P
L
I
E
I
N
-
D
E
N
D
L
D
I
A
L
R
-
I
G
A
R
F
I
G
I
N
S
R
D
L
E
T
L
--
E
I
N
K
E
N
Q
R
---
K
L
I
S
M
I
P
---
S
N
V
V
K
V
A
E
S
G
I
S
-
E
R
N
E
I
E
E
L
R
K
L
G
-
V
N
A
F
L
I
G
S
S
L
M
R
--
N
P
---
E
----------
15
PsiBlast_PDB
78.11
37%
-114
- C3 -
1JCM
5
TRPC_ECOLI
P:
[36-240]
------------------------------------------
T
------
R
H
F
--
Y
D
A
L
Q
G
-----
A
R
T
A
--
F
I
L
E
C
K
K
A
S
P
S
K
G
V
I
R
D
D
F
D
P
A
R
I
A
A
I
Y
K
H
Y
-
A
S
A
I
S
V
L
T
D
E
K
Y
F
Q
G
S
F
N
F
L
P
I
V
S
Q
I
A
-
P
Q
P
I
L
C
K
D
F
I
I
D
P
Y
Q
I
Y
L
A
R
Y
Y
-
Q
A
D
A
C
L
L
M
L
S
V
L
D
D
D
Q
Y
R
Q
L
A
A
V
A
H
S
L
E
M
G
V
L
T
E
V
S
-
N
E
E
E
Q
E
R
A
I
A
-
L
G
A
K
V
V
G
I
N
N
R
D
L
C
D
L
--
S
I
D
L
N
R
T
R
---
E
L
A
P
K
L
G
---
H
N
V
T
V
I
S
E
S
G
I
N
-
T
Y
A
Q
V
R
E
L
S
H
-
F
-
A
N
G
F
L
I
G
S
A
L
M
-------------------