@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo2592: (2016-04-05 )
MKTVKLNNGVEVPILGFGTYQITDAAEAEHAVKDAIKAGYRHIDTAQSYMNEEAVGRGIAASGVDRKELFITTKIWVENVSYKGVMSSFDRSLKRLGLDYVDLLLIHQPFNDVYGAWIAMEELQASGKIRAIGVSNFSPDRVIDLAAFNEVTPQVNQIEVNPFQQQTANLAILRKEGVAIEAWAPFAEGKNDIFNNPVLTKIGAKYGKSAAQVILRWLVEQDIIVLAKSVKPERMAQNLAIFDFELTEADKEEIAGLDQGESQFFSHADPEMVKWMASRKLNV
Atome Classification :
(61 SA)
.......-..10........20....--....30........40........50.....----...----60.----.----......70........80........90........100.....--..---110-.---------------------..---.-.--------....120.......130.......140.......---150.......160.......170.......180....-----...-----190-----.---------.......200.......210.......220.......230.......240.......250.....--------..260.-......270.......280.
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
K
T
V
KLN-NGVE
V
P
I
L
G
F
G
T
Y
Q
IT
D
A
--
A
E
A
E
H
A
V
K
D
A
I
K
A
G
Y
R
H
I
D
T
A
Q
S
Y
M
N
E
E
A
VG----RGI----AAS----G----VDR
K
E
L
F
I
T
T
K
I
W
V
ENV
S
Y
K
G
V
M
S
S
F
D
R
S
L
K
R
L
G
L
D
Y
V
D
L
L
L
IH--Q
P
---
F
---
N
---------------------
D
V
---
Y
-
G
--------
A
W
I
A
M
E
E
L
QASG
K
I
R
A
I
GVSNFSPD
R
V
I
D
L
A
A
F
N
---EVTPQV
N
Q
I
EVN
P
F
Q
QQTA
N
L
A
I
L
RKE
G
V
A
I
E
A
WAPF-----AEG-----K-N-----D---------IFNN
P
V
L
T
K
I
G
A
K
Y
G
K
S
A
A
Q
V
I
L
R
W
L
V
EQ
D
I
I
V
L
AKSV
K
P
E
R
M
A
QN
L
A
I
F
D
F
ELTEA
D
K
E
E
IAGL--------DQG
E
S
Q
-FFSHA
D
P
E
M
V
K
W
M
A
SRKLNV
1
PsiBlast_PDB
96.87
58%
-91
- C7 -
4MHB
8
?
A:
[16-297]
-
Q
T
V
K
L
N
-
N
G
I
A
M
P
L
L
G
F
G
V
F
Q
M
T
N
T
--
A
E
C
E
R
A
V
I
D
A
I
E
T
G
Y
R
L
I
D
T
A
A
S
Y
Q
N
E
T
Q
V
G
----
N
A
L
----
K
L
S
----
G
----
I
A
R
D
E
L
F
I
T
T
K
L
W
L
Q
D
T
Y
Y
E
G
A
K
A
Q
F
E
R
S
L
N
R
L
Q
L
D
Y
V
D
L
Y
L
I
H
--
Q
P
---
Y
---
G
---------------------
D
V
---
H
-
G
--------
A
W
R
A
M
E
E
L
H
Q
A
G
K
I
R
A
I
G
V
S
N
F
H
P
D
R
L
A
D
L
M
A
F
N
---
K
I
I
P
A
V
N
Q
I
E
V
N
P
F
N
Q
Q
L
H
A
V
P
W
M
Q
S
R
G
I
Q
P
E
A
W
A
P
F
-----
A
E
G
-----
R
-
N
-----
G
---------
L
F
Q
N
P
V
L
T
A
I
G
E
K
Y
G
K
S
V
G
Q
V
V
L
R
W
I
F
Q
R
G
I
V
S
L
A
K
S
V
R
K
G
R
M
E
E
N
I
N
I
L
D
F
E
L
S
A
E
D
M
L
Q
I
A
A
L
--------
D
T
A
T
S
A
-
F
F
S
H
R
D
P
A
M
V
E
W
L
T
G
R
K
L
D
V
2
PsiBlast_PDB
95.50
55%
-93
- C7 -
1VP5
1
?
A:
[18-297]
---
V
T
L
N
-
N
G
V
E
M
P
I
L
G
Y
G
V
F
Q
I
P
-
P
--
E
K
T
E
E
C
V
Y
E
A
I
K
V
G
Y
R
L
I
D
T
A
A
S
Y
M
N
E
E
G
V
G
----
R
A
I
----
K
R
A
----
I
D
E
GI
V
R
R
E
E
L
F
V
T
T
K
L
W
V
S
D
V
G
Y
E
S
T
K
K
A
F
E
K
S
L
K
K
L
Q
L
E
Y
I
D
L
Y
L
I
H
--
Q
P
---
F
---
G
---------------------
D
V
---
H
-
C
--------
A
W
K
A
M
E
E
M
Y
K
D
G
L
V
R
A
I
G
V
S
N
F
Y
P
D
R
L
M
D
L
M
V
H
H
---
E
I
V
P
A
V
N
Q
I
E
I
H
P
F
Y
Q
R
Q
E
E
I
E
F
M
R
N
Y
N
I
Q
P
E
A
W
G
P
F
-----
A
E
G
-----
R
-
K
-----
N
---------
I
F
Q
N
G
V
L
R
S
I
A
E
K
Y
G
K
T
V
A
Q
V
I
L
R
W
L
T
Q
K
G
I
V
A
I
P
K
T
V
R
R
E
R
M
K
E
N
I
S
I
F
D
F
E
L
T
Q
E
D
M
E
K
I
A
T
L
--------
D
E
G
Q
S
A
-
F
F
S
H
R
D
P
E
V
V
K
W
I
C
S
L
K
---
21
PsiBlast_CBE
95.10
55%
-95
- C7 -
1VP5
1
?
B:
[18-296]
---
V
T
L
N
-
N
G
V
E
M
P
I
L
G
Y
G
V
F
Q
I
P
-
P
--
E
K
T
E
E
C
V
Y
E
A
I
K
V
G
Y
R
L
I
D
T
A
A
S
Y
M
N
E
E
G
V
G
----
R
A
I
----
K
R
A
----
I
DEGI
V
R
R
E
E
L
F
V
T
T
K
L
W
V
S
D
V
G
Y
E
S
T
K
K
A
F
E
K
S
L
K
K
L
Q
L
E
Y
I
D
L
Y
L
I
H
--
Q
P
---
F
---
G
---------------------
D
V
---
H
-
C
--------
A
W
K
A
M
E
E
M
Y
K
D
G
L
V
R
A
I
G
V
S
N
F
Y
P
D
R
L
M
D
L
M
V
H
H
---
E
I
V
P
A
V
N
Q
I
E
I
H
P
F
Y
Q
R
Q
E
E
I
E
F
M
R
N
Y
N
I
Q
P
E
A
W
G
P
F
-----
A
E
G
-----
R
-
K
-----
N
---------
I
F
Q
N
G
V
L
R
S
I
A
E
K
Y
G
K
T
V
A
Q
V
I
L
R
W
L
T
Q
K
G
I
V
A
I
P
K
T
V
R
R
E
R
M
K
E
N
I
S
I
F
D
F
E
L
T
Q
E
D
M
E
K
I
A
T
L
--------
D
E
G
Q
S
A
-
F
F
S
H
R
D
P
E
V
V
K
W
I
C
S
L
----
101
HHSearch
93.67
55%
-87
- C7 -
1VP5
1
?
A:
[17-297]
---
K
V
T
L
N
N
G
V
E
M
P
I
L
G
Y
G
V
F
Q
I
P
P
---
E
K
T
E
E
C
V
Y
E
A
I
K
V
G
Y
R
L
I
D
T
A
A
S
Y
M
N
E
E
G
V
G
----
R
A
I
----
K
R
A
I
D
E
G
I
----
V
R
R
E
E
L
F
V
T
T
K
L
W
V
S
D
V
G
Y
E
S
T
K
K
A
F
E
K
S
L
K
K
L
Q
L
E
Y
I
D
L
Y
L
I
H
--
Q
P
---
F
---
G
---------------------
D
V
---
H
-
C
--------
A
W
K
A
M
E
E
M
Y
K
D
G
L
V
R
A
I
G
V
S
N
F
Y
P
D
R
L
M
D
L
M
V
H
H
---
E
I
V
P
A
V
N
Q
I
E
I
H
P
F
Y
Q
R
Q
E
E
I
E
F
M
R
N
Y
N
I
Q
P
E
A
W
G
P
F
-----
A
E
G
-----
R
-
K
-----
N
---------
I
F
Q
N
G
V
L
R
S
I
A
E
K
Y
G
K
T
V
A
Q
V
I
L
R
W
L
T
Q
K
G
I
V
A
I
P
K
T
V
R
R
E
R
M
K
E
N
I
S
I
F
D
F
E
L
T
Q
E
D
M
E
K
I
A
T
L
--------
D
E
G
-
Q
S
A
F
F
S
H
R
D
P
E
V
V
K
W
I
C
S
L
K
---
105
HHSearch
88.54
46%
-100
- C7 -
3O0K
4
?
A:
[26-282]
V
P
T
V
K
L
N
-
D
G
N
H
I
P
Q
L
G
Y
G
V
W
Q
I
S
N
---
D
E
A
V
S
A
V
S
E
A
L
K
A
G
Y
R
H
I
D
T
A
T
I
Y
G
N
E
E
G
V
G
----
K
A
I
----
N
G
S
----
G
----
I
A
R
A
D
I
F
L
T
T
K
L
W
N
S
D
Q
G
Y
E
S
T
L
K
A
F
D
T
S
L
K
K
L
G
T
D
Y
V
D
L
Y
L
I
H
--
W
P
---
M
---
P
S
K
D
------------------
L
F
---
M
-
E
--------
T
W
R
A
F
I
K
L
K
E
E
G
R
V
K
S
I
G
V
S
N
F
R
T
A
D
L
E
R
L
I
K
E
S
---
G
V
T
P
V
L
N
Q
I
E
L
H
P
Q
F
Q
Q
D
E
L
R
L
F
H
G
K
H
D
I
A
T
E
A
W
S
P
L
-----
G
Q
G
-----------------------
L
L
E
D
P
T
L
K
S
I
A
E
K
H
A
K
S
V
A
Q
I
I
L
R
W
H
I
E
T
G
N
I
V
I
P
K
S
I
T
P
A
R
I
K
E
N
F
D
I
F
D
F
T
L
N
G
T
D
H
D
A
I
T
K
L
-----------------------------------
10
PsiBlast_PDB
86.94
41%
-97
- C7 -
4GIE
2
PGFS_TRYCC
A:
[15-273]
--
C
V
T
L
H
-
N
S
V
R
M
P
Q
L
G
L
G
V
W
R
A
Q
D
G
--
A
E
T
A
N
A
V
R
W
A
I
E
A
G
Y
R
H
I
D
T
A
Y
I
Y
S
N
E
R
G
V
G
----
Q
G
I
----
R
E
S
----
G
----
V
P
R
E
E
V
W
V
T
T
K
V
W
N
S
D
Q
G
Y
E
K
T
L
A
A
F
E
R
S
R
E
L
L
G
L
E
Y
I
D
L
Y
L
I
H
--
W
P
---
G
---
K
---------------------
K
K
---
F
V
D
--------
T
W
K
A
L
E
K
L
Y
E
E
K
K
V
R
A
I
G
V
S
N
F
E
P
H
H
L
T
E
L
F
K
S
C
---
K
I
R
P
M
V
N
Q
V
E
L
H
P
L
F
Q
Q
R
T
L
R
E
F
C
K
Q
H
N
I
A
I
T
A
W
S
P
L
-----
G
S
G
-----
E
-
E
A----
G
---------
I
L
K
N
H
V
L
G
E
I
A
K
K
H
N
K
S
P
A
Q
V
V
I
R
W
D
I
Q
H
G
I
V
T
I
P
K
S
T
N
K
G
R
I
Q
E
N
F
N
V
W
D
F
K
L
T
E
E
E
M
R
Q
I
D
E
L
--------
N
E
-------------------------
119
HHSearch
86.93
40%
-87
- C7 -
1MZR
4
DKGA_ECOLI
A:
[26-290]
-
T
V
I
K
L
Q
-
D
G
N
V
M
P
Q
L
G
L
G
V
W
Q
A
S
N
---
E
E
V
I
T
A
I
Q
K
A
L
E
V
G
Y
R
S
I
D
T
A
A
A
Y
K
N
E
E
G
V
G
----
K
A
L
----
K
N
A
----
S
----
V
N
R
E
E
L
F
I
T
T
K
L
W
N
--
D
D
H
K
R
P
R
E
A
L
L
D
S
L
K
K
L
Q
L
D
Y
I
D
L
Y
L
M
H
--
W
P
---
V
---
P
AID------------------
H
Y
---
V
-
E
--------
A
W
K
G
M
I
E
L
Q
K
E
G
L
I
K
S
I
G
V
C
N
F
Q
I
H
H
L
Q
R
L
I
D
E
T
---
G
V
T
P
V
I
N
Q
I
E
L
H
P
L
M
Q
Q
R
Q
L
H
A
W
N
A
T
H
K
I
Q
T
E
S
W
S
P
L
-----
A
Q
G
-----
G
-
K
-----
G
---------
V
F
D
Q
K
V
I
R
D
L
A
D
K
Y
G
K
T
P
A
Q
I
V
I
R
W
H
L
D
S
G
L
V
V
I
P
K
S
V
T
P
S
R
I
A
E
N
F
D
V
W
D
F
R
L
D
K
D
E
L
G
E
I
A
K
L
--------
D
Q
G
-
K
R
-
L
G
P
D
----------------
6
PsiBlast_PDB
86.90
45%
-97
- C7 -
3O0K
4
?
A:
[28-283]
--
T
V
K
L
N
-
D
G
N
H
I
P
Q
L
G
Y
G
V
W
Q
I
S
N
D
---
E
A
V
S
A
V
S
E
A
L
K
A
G
Y
R
H
I
D
T
A
T
I
Y
G
N
E
E
G
V
G
----
K
A
I
----
N
G
S
----
G
----
I
A
R
A
D
I
F
L
T
T
K
L
W
N
S
D
Q
G
Y
E
S
T
L
K
A
F
D
T
S
L
K
K
L
G
T
D
Y
V
D
L
Y
L
I
H
--
W
P
---
M
PS-
K
---------------------
D
L
---
F
M
E
--------
T
W
R
A
F
I
K
L
K
E
E
G
R
V
K
S
I
G
V
S
N
F
R
T
A
D
L
E
R
L
I
K
E
S
---
G
V
T
P
V
L
N
Q
I
E
L
H
P
Q
F
Q
Q
D
E
L
R
L
F
H
G
K
H
D
I
A
T
E
A
W
S
P
L
-----
G
Q
G
-----------------------
L
L
E
D
P
T
L
K
S
I
A
E
K
H
A
K
S
V
A
Q
I
I
L
R
W
H
I
E
T
G
N
I
V
I
P
K
S
I
T
P
A
R
I
K
E
N
F
D
I
F
D
F
T
L
N
G
T
D
H
D
A
I
T
K
L
--------
D
--------------------------
29
PsiBlast_CBE
86.69
46%
-92
- C7 -
3F7J
7
GR_BACSU
B:
[8-265]
--
T
V
K
L
H
-
N
G
V
E
M
P
W
F
G
L
G
V
F
K
V
E
N
G
--
N
E
A
T
E
S
V
K
A
A
I
K
N
G
Y
R
S
I
D
T
A
A
I
Y
K
N
E
E
G
V
G
----
I
G
I
----
K
E
S
----
G
----
V
A
R
E
E
L
F
I
T
S
K
V
W
N
E
D
Q
G
Y
E
T
T
L
A
A
F
E
K
S
L
E
R
L
Q
L
D
Y
L
D
L
Y
L
I
H
--
W
P
---
G
---
K
---------------------
D
K
---
Y
K
D
--------
T
W
R
A
L
E
K
L
Y
K
D
G
K
I
R
A
I
G
V
S
N
F
Q
V
H
H
L
E
E
L
L
K
D
A
---
E
I
K
P
M
V
N
Q
V
E
F
H
P
R
L
T
Q
K
E
L
R
D
Y
C
K
G
Q
G
I
Q
L
E
A
W
S
P
L
-----
M
Q
G
-----
Q
-----------------
L
L
D
N
E
V
L
T
Q
I
A
E
K
H
N
K
S
V
A
Q
V
I
L
R
W
D
L
Q
H
G
V
V
T
I
P
K
S
I
K
E
H
R
I
I
E
N
A
D
I
F
D
F
E
L
S
Q
E
D
M
D
K
I
D
A
L
--------
N
K
D
E
-----------------------
26
PsiBlast_CBE
86.68
45%
-98
- C7 -
3O0K
3
?
C:
[28-283]
--
T
V
K
L
N
-
D
G
N
H
I
P
Q
L
G
Y
G
V
W
Q
I
S
N
D
---
E
A
V
S
A
V
S
E
A
L
K
A
G
Y
R
H
I
D
T
A
T
I
Y
G
N
E
E
G
V
G
----
K
A
I
----
N
G
S
----
G
----
I
A
R
A
D
I
F
L
T
T
K
L
W
N
S
D
Q
G
Y
E
S
T
L
K
A
F
D
T
S
L
K
K
L
G
T
D
Y
V
D
L
Y
L
I
H
--
W
P
---
M
PS-
K
---------------------
D
L
---
F
M
E
--------
T
W
R
A
F
I
K
L
K
E
E
G
R
V
K
S
I
G
V
S
N
F
R
T
A
D
L
E
R
L
I
K
E
S
---
G
V
T
P
V
L
N
Q
I
E
L
H
P
Q
F
Q
Q
D
E
L
R
L
F
H
G
K
H
D
I
A
T
E
A
W
S
P
L
-----
G
-------------------------
L
L
E
D
P
T
L
K
S
I
A
E
K
H
A
K
S
V
A
Q
I
I
L
R
W
H
I
E
T
G
N
I
V
I
P
K
S
I
T
P
A
R
I
K
E
N
F
D
I
F
D
F
T
L
N
G
T
D
H
D
A
I
T
K
L
--------
D
--------------------------
25
PsiBlast_CBE
86.68
45%
-97
- C7 -
3O0K
3
?
D:
[28-283]
--
T
V
K
L
N
-
D
G
N
H
I
P
Q
L
G
Y
G
V
W
Q
I
S
N
D
---
E
A
V
S
A
V
S
E
A
L
K
A
G
Y
R
H
I
D
T
A
T
I
Y
G
N
E
E
G
V
G
----
K
A
I
----
N
G
S
----
G
----
I
A
R
A
D
I
F
L
T
T
K
L
W
N
S
D
Q
G
Y
E
S
T
L
K
A
F
D
T
S
L
K
K
L
G
T
D
Y
V
D
L
Y
L
I
H
--
W
P
---
M
PS-
K
---------------------
D
L
---
F
M
E
--------
T
W
R
A
F
I
K
L
K
E
E
G
R
V
K
S
I
G
V
S
N
F
R
T
A
D
L
E
R
L
I
K
E
S
---
G
V
T
P
V
L
N
Q
I
E
L
H
P
Q
F
Q
Q
D
E
L
R
L
F
H
G
K
H
D
I
A
T
E
A
W
S
P
L
-----
G
-------
K
-----------------
L
L
E
D
P
T
L
K
S
I
A
E
K
H
A
K
S
V
A
Q
I
I
L
R
W
H
I
E
T
G
N
I
V
I
P
K
S
I
T
P
A
R
I
K
E
N
F
D
I
F
D
F
T
L
N
G
T
D
H
D
A
I
T
K
L
--------
D
--------------------------
103
HHSearch
86.55
40%
-95
- C7 -
2WZM
1
Y2407_MYCS2
A:
[11-273]
I
P
T
V
T
L
N
-
D
D
N
T
L
P
V
V
G
I
G
V
G
E
L
S
D
---
S
E
A
E
R
S
V
S
A
A
L
E
A
G
Y
R
L
I
D
T
A
A
A
Y
G
N
E
A
A
V
G
----
R
A
I
----
A
A
S
----
G
----
I
P
R
D
E
I
Y
V
T
T
K
L
A
T
P
D
Q
G
F
T
S
S
Q
A
A
A
R
A
S
L
E
R
L
G
L
D
Y
V
D
L
Y
L
I
H
--
W
P
---
G
---
G
D
T
S
------------------
K
Y
---
V
-
D
--------
S
W
G
G
L
M
K
V
K
E
D
G
I
A
R
S
I
G
V
C
N
F
G
A
E
D
L
E
T
I
V
S
L
T
---
Y
F
T
P
A
V
N
Q
I
E
L
H
P
L
L
N
Q
A
A
L
R
E
V
N
A
G
Y
N
I
V
T
E
A
Y
G
P
L
-----
G
V
G
-----
R
-----------------
L
L
D
H
P
A
V
T
A
I
A
E
A
H
G
R
T
A
A
Q
V
L
L
R
W
S
I
Q
L
G
N
V
V
I
S
R
S
A
N
P
E
R
I
A
S
N
L
D
V
F
G
F
E
L
T
A
D
E
M
E
T
L
N
G
L
--------
D
D
G
-
T
R
-
F
-------------------
3
PsiBlast_PDB
86.49
45%
-86
- C7 -
1VBJ
2
PGFS_TRYBB
A:
[10-276]
-
Q
S
L
K
L
S
-
N
G
V
M
M
P
V
L
G
F
G
M
W
K
L
Q
D
G
--
N
E
A
E
T
A
T
M
W
A
I
K
S
G
Y
R
H
I
D
T
A
A
I
Y
K
N
E
E
S
A
G
----
R
A
I
----
A
S
C
----
G
----
V
P
R
E
E
L
F
V
T
T
K
L
W
N
S
D
Q
G
Y
E
S
T
L
S
A
F
E
K
S
I
K
K
L
G
L
E
Y
V
D
L
Y
L
I
H
--
W
P
---
G
---
K
---------------------
D
K
---
F
I
D
--------
T
W
K
A
F
E
K
L
Y
A
D
K
K
V
R
A
I
G
V
S
N
F
H
E
H
H
I
E
E
L
L
K
H
C
---
K
V
A
P
M
V
N
Q
I
E
L
H
P
L
L
N
Q
K
A
L
C
E
Y
C
K
S
K
N
I
A
V
T
A
W
S
P
L
-----
G
Q
G
-----
H
-----------------
L
V
E
D
A
R
L
K
A
I
G
G
K
Y
G
K
T
A
A
Q
V
M
L
R
W
E
I
Q
A
G
V
I
T
I
P
K
S
G
N
E
A
R
I
K
E
N
G
N
I
F
D
F
E
L
T
A
E
D
I
Q
V
I
D
G
M
--------
N
A
G
H
R
Y
----
G
P
D
P
E
V
-----------
5
PsiBlast_PDB
86.47
44%
-95
- C7 -
4G5D
1
PGFS_LEIMA
A:
[13-288]
---
V
T
L
S
-
N
G
V
K
M
P
Q
F
G
L
G
V
W
Q
S
P
A
G
--
E
V
T
E
N
A
V
K
W
A
L
C
A
G
Y
R
H
I
D
T
A
A
I
Y
K
N
E
E
S
V
G
----
A
G
L
----
R
A
S
----
G
----
V
P
R
E
D
V
F
I
T
T
K
L
W
N
T
E
Q
G
Y
E
S
T
L
A
A
F
E
E
S
R
Q
K
L
G
V
D
Y
I
D
L
Y
L
I
H
--
W
P
---
R
---
G
K
--------------------
D
I
---
L
-
S
K
EGKK
Y
L
D
S
W
R
A
F
E
Q
L
Y
K
E
K
K
V
R
A
I
G
V
S
N
F
H
I
H
H
L
E
D
V
L
A
M
C
---
T
V
T
P
M
V
N
Q
V
E
L
H
P
L
N
N
Q
A
D
L
R
A
F
C
D
A
K
Q
I
K
V
E
A
W
S
P
L
-----
G
Q
G
-----
K
-----------------
L
L
S
N
P
I
L
S
A
I
G
A
K
Y
N
K
T
A
A
Q
V
I
L
R
W
N
I
Q
K
N
L
I
T
I
P
K
S
V
H
R
E
R
I
E
E
N
A
D
I
F
D
F
E
L
G
A
E
D
V
M
S
I
D
A
L
NTNSRYGP
D
P
D
E
A
Q
-
F
-------------------
33
PsiBlast_CBE
86.39
40%
-91
- C7 -
4Q3M
1
?
D:
[2-266]
-
H
S
V
K
L
N
-
N
N
Y
E
M
P
I
I
G
L
G
T
F
R
-
S
K
K
--
N
D
A
Y
N
A
V
K
A
A
L
E
G
G
Y
R
H
I
D
T
A
M
I
Y
G
N
E
E
E
V
G
----
R
A
I
----
K
D
S
----
N
----
I
P
R
E
E
I
F
V
T
T
K
L
W
N
T
D
Q
G
Y
E
K
T
L
E
A
F
N
T
S
L
K
N
L
G
L
D
Y
I
D
L
Y
L
I
H
WF
K
G
---
Y
---
D
---------------------
N
A
---
L
-
S
--------
T
Y
R
A
F
E
T
L
Y
E
E
G
K
V
K
A
I
G
V
S
N
F
N
V
H
H
L
M
Y
L
M
E
N
A
---
K
I
P
P
M
V
N
Q
V
E
T
H
V
T
L
Q
N
H
F
L
H
D
Y
C
K
K
N
N
I
Q
L
E
A
Y
A
P
L
-----
M
S
H
-----
Q
I
K
-----
D
---------
L
L
S
N
E
T
M
A
K
I
A
K
K
H
D
K
T
I
P
Q
I
A
I
R
W
L
I
E
R
E
I
V
V
I
P
K
S
I
T
P
E
R
I
V
Q
N
F
D
V
F
D
F
T
L
D
E
E
D
M
K
S
I
R
S
V
--------
N
T
G
K
K
I
-
F
-------------------
32
PsiBlast_CBE
86.23
40%
-89
- C7 -
4Q3M
1
?
E:
[3-266]
--
S
V
K
L
N
-
N
N
Y
E
M
P
I
I
G
L
G
T
F
R
-
S
K
K
--
N
D
A
Y
N
A
V
K
A
A
L
E
G
G
Y
R
H
I
D
T
A
M
I
Y
G
N
E
E
E
V
G
----
R
A
I
----
K
D
S
----
N
----
I
P
R
E
E
I
F
V
T
T
K
L
W
N
T
D
Q
G
Y
E
K
T
L
E
A
F
N
T
S
L
K
N
L
G
L
D
Y
I
D
L
Y
L
I
H
WF
K
G
---
Y
---
D
---------------------
N
A
---
L
-
S
--------
T
Y
R
A
F
E
T
L
Y
E
E
G
K
V
K
A
I
G
V
S
N
F
N
V
H
H
L
M
Y
L
M
E
N
A
---
K
I
P
P
M
V
N
Q
V
E
T
H
V
T
L
Q
N
H
F
L
H
D
Y
C
K
K
N
N
I
Q
L
E
A
Y
A
P
L
-----
M
S
H
-----
Q
I
K
-----
D
---------
L
L
S
N
E
T
M
A
K
I
A
K
K
H
D
K
T
I
P
Q
I
A
I
R
W
L
I
E
R
E
I
V
V
I
P
K
S
I
T
P
E
R
I
V
Q
N
F
D
V
F
D
F
T
L
D
E
E
D
M
K
S
I
R
S
V
--------
N
T
G
K
K
I
-
F
-------------------
27
PsiBlast_CBE
86.18
45%
-101
- C7 -
3O0K
4
?
B:
[28-283]
--
T
V
K
L
N
-
D
G
N
H
I
P
Q
L
G
Y
G
V
W
Q
I
S
N
D
---
E
A
V
S
A
V
S
E
A
L
K
A
G
Y
R
H
I
D
T
A
T
I
Y
G
N
E
E
G
V
G
----
K
A
I
----
N
G
S
----
G
----
I
A
R
A
D
I
F
L
T
T
K
L
W
N
S
D
Q
G
Y
E
S
T
L
K
A
F
D
T
S
L
K
K
L
G
T
D
Y
V
D
L
Y
L
I
H
--
W
P
---
M
PS-
K
---------------------
D
L
---
F
M
E
--------
T
W
R
A
F
I
K
L
K
E
E
G
R
V
K
S
I
G
V
S
N
F
R
T
A
D
L
E
R
L
I
K
E
S
---
G
V
T
P
V
L
N
Q
I
E
L
H
P
Q
F
Q
Q
D
E
L
R
L
F
H
G
K
H
D
I
A
T
E
A
W
S
P
L
-----
G
-------------------------
L
L
E
D
P
T
L
K
S
I
A
E
K
H
A
K
S
V
A
Q
I
I
L
R
W
H
I
E
T
G
N
I
V
I
P
K
S
I
T
P
A
R
I
K
E
N
F
D
I
F
D
F
T
L
N
G
T
D
H
D
A
I
T
K
L
--------
D
--------------------------
11
PsiBlast_PDB
86.06
40%
-91
- C7 -
4Q3M
1
?
A:
[2-266]
-
H
S
V
K
L
N
-
N
N
Y
E
M
P
I
I
G
L
G
T
F
R
-
S
K
K
--
N
D
A
Y
N
A
V
K
A
A
L
E
G
G
Y
R
H
I
D
T
A
M
I
Y
G
N
E
E
E
V
G
----
R
A
I
----
K
D
S
----
N
----
I
P
R
E
E
I
F
V
T
T
K
L
W
N
T
D
Q
G
Y
E
K
T
L
E
A
F
N
T
S
L
K
N
L
G
L
D
Y
I
D
L
Y
L
I
H
WF
K
G
---
Y
---
D
---------------------
N
A
---
L
-
S
--------
T
Y
R
A
F
E
T
L
Y
E
E
G
K
V
K
A
I
G
V
S
N
F
N
V
H
H
L
M
Y
L
M
E
N
A
---
K
I
P
P
M
V
N
Q
V
E
T
H
V
T
L
Q
N
H
F
L
H
D
Y
C
K
K
N
N
I
Q
L
E
A
Y
A
P
L
-----
M
S
H
-----
Q
I
K
-----
D
---------
L
L
S
N
E
T
M
A
K
I
A
K
K
H
D
K
T
I
P
Q
I
A
I
R
W
L
I
E
R
E
I
V
V
I
P
K
S
I
T
P
E
R
I
V
Q
N
F
D
V
F
D
F
T
L
D
E
E
D
M
K
S
I
R
S
V
--------
N
T
G
K
K
I
-
F
-------------------
7
PsiBlast_PDB
85.95
46%
-91
- C7 -
3D3F
1
GR_BACSU
A:
[7-264]
--
T
V
K
L
H
-
N
G
V
E
M
P
W
F
G
L
G
V
F
K
V
E
N
G
--
N
E
A
T
E
S
V
K
A
A
I
K
N
G
Y
R
S
I
D
T
A
A
I
Y
K
N
E
E
G
V
G
----
I
G
I
----
K
E
S
----
G
----
V
A
R
E
E
L
F
I
T
S
K
V
W
N
E
D
Q
G
Y
E
T
T
L
A
A
F
E
K
S
L
E
R
L
Q
L
D
Y
L
D
L
Y
L
I
H
--
W
P
---
G
---
K
---------------------
D
K
---
Y
K
D
--------
T
W
R
A
L
E
K
L
Y
K
D
G
K
I
R
A
I
G
V
S
N
F
Q
V
H
H
L
E
E
L
L
K
D
A
---
E
I
K
P
M
V
N
Q
V
E
F
H
P
R
L
T
Q
K
E
L
R
D
Y
C
K
G
Q
G
I
Q
L
E
A
W
S
P
L
-----
M
Q
G
-----
Q
-----------------
L
L
D
N
E
V
L
T
Q
I
A
E
K
H
N
K
S
V
A
Q
V
I
L
R
W
D
L
Q
H
G
V
V
T
I
P
K
S
I
K
E
H
R
I
I
E
N
A
D
I
F
D
F
E
L
S
Q
E
D
M
D
K
I
D
A
L
--------
N
K
D
E
-----------------------
34
PsiBlast_CBE
85.90
40%
-91
- C7 -
4Q3M
1
?
C:
[2-266]
-
H
S
V
K
L
N
-
N
N
Y
E
M
P
I
I
G
L
G
T
F
R
-
S
K
K
--
N
D
A
Y
N
A
V
K
A
A
L
E
G
G
Y
R
H
I
D
T
A
M
I
Y
G
N
E
E
E
V
G
----
R
A
I
----
K
D
S
----
N
----
I
P
R
E
E
I
F
V
T
T
K
L
W
N
T
D
Q
G
Y
E
K
T
L
E
A
F
N
T
S
L
K
N
L
G
L
D
Y
I
D
L
Y
L
I
H
W
F
K
G
---
Y
---
D
---------------------
N
A
---
L
-
S
--------
T
Y
R
A
F
E
T
L
Y
E
E
G
K
V
K
A
I
G
V
S
N
F
N
V
H
H
L
M
Y
L
M
E
N
A
---
K
I
P
P
M
V
N
Q
V
E
T
H
V
T
L
Q
N
H
F
L
H
D
Y
C
K
K
N
N
I
Q
L
E
A
Y
A
P
L
-----
M
S
H
-----
Q
I
K
-----
D
---------
L
L
S
N
E
T
M
A
K
I
A
K
K
H
D
K
T
I
P
Q
I
A
I
R
W
L
I
E
R
E
I
V
V
I
P
K
S
I
T
P
E
R
I
V
Q
N
F
D
V
F
D
F
T
L
D
E
E
D
M
K
S
I
R
S
V
--------
N
T
G
K
K
I
-
F
-------------------
102
HHSearch
85.62
46%
-88
- C7 -
1VBJ
2
PGFS_TRYBB
A:
[13-279]
----
K
L
S
-
N
G
V
M
M
P
V
L
G
F
G
M
W
K
L
Q
D
G
--
N
E
A
E
T
A
T
M
W
A
I
K
S
G
Y
R
H
I
D
T
A
A
I
Y
K
N
E
E
S
A
G
----
R
A
I
----
A
S
C
----
G
----
V
P
R
E
E
L
F
V
T
T
K
L
W
N
S
D
Q
G
Y
E
S
T
L
S
A
F
E
K
S
I
K
K
L
G
L
E
Y
V
D
L
Y
L
I
H
--
W
P
---
G
---
K
D--------------------
K
F
---
I
-
D
--------
T
W
K
A
F
E
K
L
Y
A
D
K
K
V
R
A
I
G
V
S
N
F
H
E
H
H
I
E
E
L
L
K
H
C
---
K
V
A
P
M
V
N
Q
I
E
L
H
P
L
L
N
Q
K
A
L
C
E
Y
C
K
S
K
N
I
A
V
T
A
W
S
P
L
-----
G
Q
G
-----
H
-----------------
L
V
E
D
A
R
L
K
A
I
G
G
K
Y
G
K
T
A
A
Q
V
M
L
R
W
E
I
Q
A
G
V
I
T
I
P
K
S
G
N
E
A
R
I
K
E
N
G
N
I
F
D
F
E
L
T
A
E
D
I
Q
V
I
D
G
M
--------
N
A
G
-
H
R
-
Y
G
----
P
D
P
E
V
F
M
N
------
13
PsiBlast_PDB
85.62
39%
-94
- C7 -
2WZM
1
Y2407_MYCS2
A:
[11-270]
I
P
T
V
T
L
N
-
D
D
N
T
L
P
V
V
G
I
G
V
G
E
L
S
D
S
---
E
A
E
R
S
V
S
A
A
L
E
A
G
Y
R
L
I
D
T
A
A
A
Y
G
N
E
A
A
V
G
----
R
A
I
----
A
A
S
----
G
----
I
P
R
D
E
I
Y
V
T
T
K
L
A
T
P
D
Q
G
F
T
S
S
Q
A
A
A
R
A
S
L
E
R
L
G
L
D
Y
V
D
L
Y
L
I
H
--
W
P
---
G
---
G
---------------------
D
T
S
K
Y
V
-
D
--------
S
W
G
G
L
M
K
V
K
E
D
G
I
A
R
S
I
G
V
C
N
F
G
A
E
D
L
E
T
I
V
S
L
T
---
Y
F
T
P
A
V
N
Q
I
E
L
H
P
L
L
N
Q
A
A
L
R
E
V
N
A
G
Y
N
I
V
T
E
A
Y
G
P
L
-----
G
V
G
-----
R
-----------------
L
L
D
H
P
A
V
T
A
I
A
E
A
H
G
R
T
A
A
Q
V
L
L
R
W
S
I
Q
L
G
N
V
V
I
S
R
S
A
N
P
E
R
I
A
S
N
L
D
V
F
G
F
E
L
T
A
D
E
M
E
T
L
N
G
L
--------
D
D
G
------------------------
24
PsiBlast_CBE
85.54
44%
-98
- C7 -
4F40
10
PGFS_LEIMA
B:
[13-288]
---
V
T
L
S
-
N
G
V
K
M
P
Q
F
G
L
G
V
W
Q
S
P
A
G
--
E
V
T
E
N
A
V
K
W
A
L
C
A
G
Y
R
H
I
D
T
A
A
I
Y
K
N
E
E
S
V
G
----
A
G
L
----
R
A
S
----
G
----
V
P
R
E
D
V
F
I
T
T
K
L
W
N
T
E
Q
G
Y
E
S
T
L
A
A
F
E
E
S
R
Q
K
L
G
V
D
Y
I
D
L
Y
L
I
H
--
W
P
---
R
---
G
K--------------------
D
I
---
L
-
S
KEGKKYLD
S
W
R
A
F
E
Q
L
Y
K
E
K
K
V
R
A
I
G
V
S
N
F
H
I
H
H
L
E
D
V
L
A
M
C
---
T
V
T
P
M
V
N
Q
V
E
L
H
P
L
N
N
Q
A
D
L
R
A
F
C
D
A
K
Q
I
K
V
E
A
W
S
P
L
-----
G
-------
K
-----------------
L
L
S
N
P
I
L
S
A
I
G
A
K
Y
N
K
T
A
A
Q
V
I
L
R
W
N
I
Q
K
N
L
I
T
I
P
K
S
V
H
R
E
R
I
E
E
N
A
D
I
F
D
F
E
L
G
A
E
D
V
M
S
I
D
A
L
NTNSRYGP
D
P
D
E
A
Q
-
F
-------------------
22
PsiBlast_CBE
85.46
45%
-85
- C7 -
1VBJ
2
PGFS_TRYBB
B:
[10-276]
-
Q
S
L
K
L
S
-
N
G
V
M
M
P
V
L
G
F
G
M
W
K
L
Q
D
G
--
N
E
A
E
T
A
T
M
W
A
I
K
S
G
Y
R
H
I
D
T
A
A
I
Y
K
N
E
E
S
A
G
----
R
A
I
----
A
S
C
----
G
----
V
P
R
E
E
L
F
V
T
T
K
L
W
N
S
D
Q
G
Y
E
S
T
L
S
A
F
E
K
S
I
K
K
L
G
L
E
Y
V
D
L
Y
L
I
H
--
W
P
---
G
---
K
---------------------
D
K
---
F
I
D
--------
T
W
K
A
F
E
K
L
Y
A
D
K
K
V
R
A
I
G
V
S
N
F
H
E
H
H
I
E
E
L
L
K
H
C
---
K
V
A
P
M
V
N
Q
I
E
L
H
P
L
L
N
Q
K
A
L
C
E
Y
C
K
S
K
N
I
A
V
T
A
W
S
P
L
-----
G
Q
G
-----
H
-----------------
L
V
E
D
A
R
L
K
A
I
G
G
K
Y
G
K
T
A
A
Q
V
M
L
R
W
E
I
Q
A
G
V
I
T
I
P
K
S
G
N
E
A
R
I
K
E
N
G
N
I
F
D
F
E
L
T
A
E
D
I
Q
V
I
D
G
M
--------
N
A
G
H
R
Y
----
G
P
D
P
E
V
-----------
19
PsiBlast_PDB
85.43
39%
-86
- C7 -
1A80
1
DKGA_CORSC
A:
[2-276]
V
P
S
I
V
L
N
-
D
G
N
S
I
P
Q
L
G
Y
G
V
F
K
V
P
-
P
--
A
D
T
Q
R
A
V
E
E
A
L
E
V
G
Y
R
H
I
D
T
A
A
I
Y
G
N
E
E
G
V
G
----
A
A
I
----
A
A
S
----
G
----
I
A
R
D
D
L
F
I
T
T
K
L
W
N
D
R
H
D
G
D
E
P
A
A
A
I
A
E
S
L
A
K
L
A
L
D
Q
V
D
L
Y
L
V
H
--
W
P
---
T
PAA
D
---------------------
N
Y
---
V
-
H
--------
A
W
E
K
M
I
E
L
R
A
A
G
L
T
R
S
I
G
V
S
N
H
L
V
P
H
L
E
R
I
V
A
A
T
---
G
V
V
P
A
V
N
Q
I
E
L
H
P
A
Y
Q
Q
R
E
I
T
D
W
A
A
A
H
D
V
K
I
E
S
W
G
P
L
-----
G
Q
G
-----
K
-
Y
-----
D
---------
L
F
G
A
E
P
V
T
A
A
A
A
A
H
G
K
T
P
A
Q
A
V
L
R
W
H
L
Q
K
G
F
V
V
F
P
K
S
V
R
R
E
R
L
E
E
N
L
D
V
F
D
F
D
L
T
D
T
E
I
A
A
I
D
A
M
--------
D
P
G
D
G
S
-
G
R
V
S
A
H
P
D
E
V
----------
28
PsiBlast_CBE
85.39
46%
-94
- C7 -
3D3F
1
GR_BACSU
B:
[7-264]
--
T
V
K
L
H
-
N
G
V
E
M
P
W
F
G
L
G
V
F
K
V
E
N
G
--
N
E
A
T
E
S
V
K
A
A
I
K
N
G
Y
R
S
I
D
T
A
A
I
Y
K
N
E
E
G
V
G
----
I
G
I
----
K
E
S
----
G
----
V
A
R
E
E
L
F
I
T
S
K
V
W
N
E
D
Q
G
Y
E
T
T
L
A
A
F
E
K
S
L
E
R
L
Q
L
D
Y
L
D
L
Y
L
I
H
--
W
P
---
G
---
K
---------------------
D
K
---
Y
K
D
--------
T
W
R
A
L
E
K
L
Y
K
D
G
K
I
R
A
I
G
V
S
N
F
Q
V
H
H
L
E
E
L
L
K
D
A
---
E
I
K
P
M
V
N
Q
V
E
F
H
P
R
L
T
Q
K
E
L
R
D
Y
C
K
G
Q
G
I
Q
L
E
A
W
S
P
L
-----
M
Q
G
-----
Q
-----------------
L
L
D
N
E
V
L
T
Q
I
A
E
K
H
N
K
S
V
A
Q
V
I
L
R
W
D
L
Q
H
G
V
V
T
I
P
K
S
I
K
E
H
R
I
I
E
N
A
D
I
F
D
F
E
L
S
Q
E
D
M
D
K
I
D
A
L
--------
N
K
D
E
-----------------------
9
PsiBlast_PDB
85.32
41%
-95
- C7 -
4FZI
1
PGFS_TRYCC
A:
[15-273]
--
C
V
T
L
H
-
N
S
V
R
M
P
Q
L
G
L
G
V
W
R
A
Q
D
G
--
A
E
T
A
N
A
V
R
W
A
I
E
A
G
Y
R
H
I
D
T
A
Y
I
Y
S
N
E
R
G
V
G
----
Q
G
I
----
R
E
S
----
G
----
V
P
R
E
E
V
W
V
T
T
K
V
W
N
S
D
Q
G
Y
E
K
T
L
A
A
F
E
R
S
R
E
L
L
G
L
E
Y
I
D
L
Y
L
I
H
--
W
P
---
G
---
K
---------------------
K
K
---
F
V
D
--------
T
W
K
A
L
E
K
L
Y
E
E
K
K
V
R
A
I
G
V
S
N
F
E
P
H
H
L
T
E
L
F
K
S
C
---
K
I
R
P
M
V
N
Q
V
E
L
H
P
L
F
Q
Q
R
T
L
R
E
F
C
K
Q
H
N
I
A
I
T
A
W
S
P
L
-----
G
S
G
-----
E
-
E
A----
G
---------
I
L
K
N
H
V
L
G
E
I
A
K
K
H
N
K
S
P
A
Q
V
V
I
R
W
D
I
Q
H
G
I
V
T
I
P
K
S
T
N
K
G
R
I
Q
E
N
F
N
V
W
D
F
K
L
T
E
E
E
M
R
Q
I
D
E
L
--------
N
E
-------------------------
15
PsiBlast_PDB
85.29
40%
-87
- C7 -
1MZR
4
DKGA_ECOLI
A:
[28-285]
---
I
K
L
Q
-
D
G
N
V
M
P
Q
L
G
L
G
V
W
Q
A
S
N
E
---
E
V
I
T
A
I
Q
K
A
L
E
V
G
Y
R
S
I
D
T
A
A
A
Y
K
N
E
E
G
V
G
----
K
A
L
----
K
N
A
----
S
----
V
N
R
E
E
L
F
I
T
T
K
L
W
--
N
D
D
H
K
R
P
R
E
A
L
L
D
S
L
K
K
L
Q
L
D
Y
I
D
L
Y
L
M
H
--
W
P
VPA
I
---
D
---------------------
H
Y
---
V
-
E
--------
A
W
K
G
M
I
E
L
Q
K
E
G
L
I
K
S
I
G
V
C
N
F
Q
I
H
H
L
Q
R
L
I
D
E
T
---
G
V
T
P
V
I
N
Q
I
E
L
H
P
L
M
Q
Q
R
Q
L
H
A
W
N
A
T
H
K
I
Q
T
E
S
W
S
P
L
-----
A
Q
G
-----
G
-
K
-----
G
---------
V
F
D
Q
K
V
I
R
D
L
A
D
K
Y
G
K
T
P
A
Q
I
V
I
R
W
H
L
D
S
G
L
V
V
I
P
K
S
V
T
P
S
R
I
A
E
N
F
D
V
W
D
F
R
L
D
K
D
E
L
G
E
I
A
K
L
--------
D
Q
G
K
-----------------------
4
PsiBlast_PDB
85.27
44%
-95
- C7 -
4F40
11
PGFS_LEIMA
A:
[13-288]
---
V
T
L
S
-
N
G
V
K
M
P
Q
F
G
L
G
V
W
Q
S
P
A
G
--
E
V
T
E
N
A
V
K
W
A
L
C
A
G
Y
R
H
I
D
T
A
A
I
Y
K
N
E
E
S
V
G
----
A
G
L
----
R
A
S
----
G
----
V
P
R
E
D
V
F
I
T
T
K
L
W
N
T
E
Q
G
Y
E
S
T
L
A
A
F
E
E
S
R
Q
K
L
G
V
D
Y
I
D
L
Y
L
I
H
--
W
P
---
R
---
G
K
--------------------
D
I
---
L
-
S
K
EGKK
Y
L
D
S
W
R
A
F
E
Q
L
Y
K
E
K
K
V
R
A
I
G
V
S
N
F
H
I
H
H
L
E
D
V
L
A
M
C
---
T
V
T
P
M
V
N
Q
V
E
L
H
P
L
N
N
Q
A
D
L
R
A
F
C
D
A
K
Q
I
K
V
E
A
W
S
P
L
-----
G
-------
K
-----------------
L
L
S
N
P
I
L
S
A
I
G
A
K
Y
N
K
T
A
A
Q
V
I
L
R
W
N
I
Q
K
N
L
I
T
I
P
K
S
V
H
R
E
R
I
E
E
N
A
D
I
F
D
F
E
L
G
A
E
D
V
M
S
I
D
A
L
NTNSRYGP
D
P
D
E
A
Q
-
F
-------------------
36
PsiBlast_CBE
85.22
39%
-93
- C7 -
2WZM
1
Y2407_MYCS2
B:
[11-270]
I
P
T
V
T
L
N
-
D
D
N
T
L
P
V
V
G
I
G
V
G
E
L
S
D
S
---
E
A
E
R
S
V
S
A
A
L
E
A
G
Y
R
L
I
D
T
A
A
A
Y
G
N
E
A
A
V
G
----
R
A
I
----
A
A
S
----
G
----
I
P
R
D
E
I
Y
V
T
T
K
L
A
T
P
D
Q
G
F
T
S
S
Q
A
A
A
R
A
S
L
E
R
L
G
L
D
Y
V
D
L
Y
L
I
H
--
W
P
---
G
---
G
---------------------
D
T
SKY
V
-
D
--------
S
W
G
G
L
M
K
V
K
E
D
G
I
A
R
S
I
G
V
C
N
F
G
A
E
D
L
E
T
I
V
S
L
T
---
Y
F
T
P
A
V
N
Q
I
E
L
H
P
L
L
N
Q
A
A
L
R
E
V
N
A
G
Y
N
I
V
T
E
A
Y
G
P
L
-----
G
V
G
-----
R
-----------------
L
L
D
H
P
A
V
T
A
I
A
E
A
H
G
R
T
A
A
Q
V
L
L
R
W
S
I
Q
L
G
N
V
V
I
S
R
S
A
N
P
E
R
I
A
S
N
L
D
V
F
G
F
E
L
T
A
D
E
M
E
T
L
N
G
L
--------
D
D
G
------------------------
20
PsiBlast_PDB
85.05
39%
-86
- C7 -
1M9H
2
DKGA_CORSC
A:
[3-277]
V
P
S
I
V
L
N
-
D
G
N
S
I
P
Q
L
G
Y
G
V
Y
K
V
P
-
P
--
A
D
T
Q
R
A
V
E
E
A
L
E
V
G
Y
R
H
I
D
T
A
A
I
Y
G
N
E
E
G
V
G
----
A
A
I
----
A
A
S
----
G
----
I
A
R
D
D
L
F
I
T
T
K
L
W
N
D
R
H
D
G
D
E
P
A
A
A
I
A
E
S
L
A
K
L
A
L
D
Q
V
D
L
Y
L
V
H
--
W
P
---
T
PAA
D
---------------------
N
Y
---
V
-
H
--------
A
W
E
K
M
I
E
L
R
A
A
G
L
T
R
S
I
G
V
S
N
H
L
V
P
H
L
E
R
I
V
A
A
T
---
G
V
V
P
A
V
N
Q
I
E
L
H
P
A
Y
Q
Q
R
E
I
T
D
W
A
A
A
H
D
V
K
I
E
S
W
G
P
L
-----
G
Q
G
-----
K
-
Y
-----
D
---------
L
F
G
A
E
P
V
T
A
A
A
A
A
H
G
K
T
P
A
Q
A
V
L
R
W
H
L
Q
K
G
F
V
V
F
P
G
S
V
R
R
E
H
L
E
E
N
L
D
V
F
D
F
D
L
T
D
T
E
I
A
A
I
D
A
M
--------
D
P
G
D
G
S
-
G
R
V
S
G
H
P
D
E
V
----------
23
PsiBlast_CBE
84.89
44%
-94
- C7 -
4G5D
1
PGFS_LEIMA
B:
[13-288]
---
V
T
L
S
-
N
G
V
K
M
P
Q
F
G
L
G
V
W
Q
S
P
A
G
--
E
V
T
E
N
A
V
K
W
A
L
C
A
G
Y
R
H
I
D
T
A
A
I
Y
K
N
E
E
S
V
G
----
A
G
L
----
R
A
S
----
G
----
V
P
R
E
D
V
F
I
T
T
K
L
W
N
T
E
Q
G
Y
E
S
T
L
A
A
F
E
E
S
R
Q
K
L
G
V
D
Y
I
D
L
Y
L
I
H
--
W
P
---
R
---
G
K
--------------------
D
I
---
L
-
S
K
EGKK
Y
L
D
S
W
R
A
F
E
Q
L
Y
K
E
K
K
V
R
A
I
G
V
S
N
F
H
I
H
H
L
E
D
V
L
A
M
C
---
T
V
T
P
M
V
N
Q
V
E
L
H
P
L
N
N
Q
A
D
L
R
A
F
C
D
A
K
Q
I
K
V
E
A
W
S
P
L
-----
G
Q
G
-----
K
-----------------
L
L
S
N
P
I
L
S
A
I
G
A
K
Y
N
K
T
A
A
Q
V
I
L
R
W
N
I
Q
K
N
L
I
T
I
P
K
S
V
H
R
E
R
I
E
E
N
A
D
I
F
D
F
E
L
G
A
E
D
V
M
S
I
D
A
L
NTNSRYGP
D
P
D
E
A
Q
-
F
-------------------
30
PsiBlast_CBE
84.76
41%
-95
- C7 -
4FZI
2
PGFS_TRYCC
B:
[15-273]
--
C
V
T
L
H
-
N
S
V
R
M
P
Q
L
G
L
G
V
W
R
A
Q
D
G
--
A
E
T
A
N
A
V
R
W
A
I
E
A
G
Y
R
H
I
D
T
A
Y
I
Y
S
N
E
R
G
V
G
----
Q
G
I
----
R
E
S
----
G
----
V
P
R
E
E
V
W
V
T
T
K
V
W
N
S
D
Q
G
Y
E
K
T
L
A
A
F
E
R
S
R
E
L
L
G
L
E
Y
I
D
L
Y
L
I
H
--
W
P
---
G
---
K
---------------------
K
K
---
F
V
D
--------
T
W
K
A
L
E
K
L
Y
E
E
K
K
V
R
A
I
G
V
S
N
F
E
P
H
H
L
T
E
L
F
K
S
C
---
K
I
R
P
M
V
N
Q
V
E
L
H
P
L
F
Q
Q
R
T
L
R
E
F
C
K
Q
H
N
I
A
I
T
A
W
S
P
L
-----
G
S
------------------------
I
L
K
N
H
V
L
G
E
I
A
K
K
H
N
K
S
P
A
Q
V
V
I
R
W
D
I
Q
H
G
I
V
T
I
P
K
S
T
N
K
G
R
I
Q
E
N
F
N
V
W
D
F
K
L
T
E
E
E
M
R
Q
I
D
E
L
--------
N
E
-------------------------
99
PsiBlast_CBE
84.66
32%
-93
- C7 -
4L1X
3
AK1C2_HUMAN
B:
[8-304]
-
Q
C
V
K
L
N
-
D
G
H
F
M
P
V
L
G
F
G
T
Y
A
P
A
E
V
PK
S
K
A
L
E
A
V
K
L
A
I
E
A
G
F
H
H
I
D
S
A
H
L
Y
N
N
E
E
Q
V
G
----
L
A
I
RSKI
A
D
G
----
S
----
V
K
R
E
D
I
F
Y
T
S
K
L
W
S
N
S
H
R
P
E
L
V
R
P
A
L
E
R
S
L
K
N
L
Q
L
D
Y
V
D
L
Y
L
I
H
--
F
P
---
V
---
S
VKPGEEVIPKDENGKILFDTV
D
L
---
C
-
A
--------
T
W
E
A
M
E
K
C
K
D
A
G
L
A
K
S
I
G
V
S
N
F
N
-
H
R
L
L
E
M
I
L
N
K
PGL
K
Y
K
P
V
C
N
Q
V
E
C
H
P
Y
F
N
Q
R
K
L
L
D
F
C
K
S
K
D
I
V
L
V
A
Y
S
A
L
-----
G
S
H
-----
R
-
E
-----
E
PWVDPNSPV
L
L
E
D
P
V
L
C
A
L
A
K
K
H
K
R
T
P
A
L
I
A
L
R
Y
Q
L
Q
R
G
V
V
V
L
A
K
S
Y
N
E
Q
R
I
R
Q
N
V
Q
V
F
E
F
Q
L
T
S
E
E
M
K
A
I
D
G
L
--------
N
R
N
------------------------
87
PsiBlast_CBE
84.52
32%
-96
- C7 -
4JTQ
9
AK1C2_HUMAN
B:
[6-302]
-
Q
C
V
K
L
N
-
D
G
H
F
M
P
V
L
G
F
G
T
Y
A
P
A
E
V
PK
S
K
A
L
E
A
V
K
L
A
I
E
A
G
F
H
H
I
D
S
A
H
V
Y
N
N
E
E
Q
V
G
----
L
A
I
R
S
K
I
A
D
G
----
S
----
V
K
R
E
D
I
F
Y
T
S
K
L
W
S
N
S
H
R
P
E
L
V
R
P
A
L
E
R
S
L
K
N
L
Q
L
D
Y
V
D
L
Y
L
I
H
--
F
P
---
V
---
S
VKPGEEV
I
P
K
D
ENGKIL
F
D
T
V
D
L
---
C
-
A
--------
T
W
E
A
M
E
K
C
K
D
A
G
L
A
K
S
I
G
V
S
N
F
N
-
H
R
L
L
E
M
I
L
N
K
PGL
K
Y
K
P
V
C
N
Q
V
E
C
H
P
Y
F
N
Q
R
K
L
L
D
F
C
K
S
K
D
I
V
L
V
A
Y
S
A
L
-----
G
S
H
-----
R
-
E
-----
E
PWVDPNSPV
L
L
E
D
P
V
L
C
A
L
A
K
K
H
K
R
T
P
A
L
I
A
L
R
Y
Q
L
Q
R
G
V
V
V
L
A
K
S
Y
N
E
Q
R
I
R
Q
N
V
Q
V
F
E
F
Q
L
T
S
E
E
M
K
A
I
D
G
L
--------
N
R
N
------------------------
83
PsiBlast_CBE
84.40
32%
-95
- C7 -
1J96
3
AK1C2_HUMAN
B:
[6-302]
-
Q
C
V
K
L
N
-
D
G
H
F
M
P
V
L
G
F
G
T
Y
A
P
A
E
V
PK
S
K
A
L
E
A
V
K
L
A
I
E
A
G
F
H
H
I
D
S
A
H
V
Y
N
N
E
E
Q
V
G
----
L
A
I
R
S
K
I
A
D
G
----
S
----
V
K
R
E
D
I
F
Y
T
S
K
L
W
S
N
S
H
R
P
E
L
V
R
P
A
L
E
R
S
L
K
N
L
Q
L
D
Y
V
D
L
Y
L
I
H
--
F
P
---
V
---
S
V
K
PGEEVIPKI
L
F
D
T
V
-----
D
L
---
C
-
A
--------
T
W
E
A
M
E
K
C
K
D
A
G
L
A
K
S
I
G
V
S
N
F
N
-
H
R
L
L
E
M
I
L
N
K
PGL
K
Y
K
P
V
C
N
Q
V
E
C
H
P
Y
F
N
Q
R
K
L
L
D
F
C
K
S
K
D
I
V
L
V
A
Y
S
A
L
-----
G
S
H
-----
R
-
E
-----
E
PWVDPNSPV
L
L
E
D
P
V
L
C
A
L
A
K
K
H
K
R
T
P
A
L
I
A
L
R
Y
Q
L
Q
R
G
V
V
V
L
A
K
S
Y
N
E
Q
R
I
R
Q
N
V
Q
V
F
E
F
Q
L
T
S
E
E
M
K
A
I
D
G
L
--------
N
R
N
------------------------
84
PsiBlast_CBE
84.38
32%
-97
- C7 -
1J96
3
AK1C2_HUMAN
A:
[6-302]
-
Q
C
V
K
L
N
-
D
G
H
F
M
P
V
L
G
F
G
T
Y
A
P
A
E
V
P
K
S
K
A
L
E
A
V
K
L
A
I
E
A
G
F
H
H
I
D
S
A
H
V
Y
N
N
E
E
Q
V
G
----
L
A
I
R
S
K
I
A
D
G
----
S
----
V
K
R
E
D
I
F
Y
T
S
K
L
W
S
N
S
H
R
P
E
L
V
R
P
A
L
E
R
S
L
K
N
L
Q
L
D
Y
V
D
L
Y
L
I
H
--
F
P
---
V
---
S
V
K
PGEEVIPKDENGKI
L
F
D
T
V
D
L
---
C
-
A
--------
T
W
E
A
M
E
K
C
K
D
A
G
L
A
K
S
I
G
V
S
N
F
N
-
H
R
L
L
E
M
I
L
N
K
PGL
K
Y
K
P
V
C
N
Q
V
E
C
H
P
Y
F
N
Q
R
K
L
L
D
F
C
K
S
K
D
I
V
L
V
A
Y
S
A
L
-----
G
S
H
-----
R
-
E
-----
E
PWVDPNSPV
L
L
E
D
P
V
L
C
A
L
A
K
K
H
K
R
T
P
A
L
I
A
L
R
Y
Q
L
Q
R
G
V
V
V
L
A
K
S
Y
N
E
Q
R
I
R
Q
N
V
Q
V
F
E
F
Q
L
T
S
E
E
M
K
A
I
D
G
L
--------
N
R
N
------------------------
85
PsiBlast_CBE
83.84
32%
-96
- C7 -
4JTR
7
AK1C2_HUMAN
B:
[6-302]
-
Q
C
V
K
L
N
-
D
G
H
F
M
P
V
L
G
F
G
T
Y
A
P
A
E
V
P
K
S
K
A
L
E
A
V
K
L
A
I
E
A
G
F
H
H
I
D
S
A
H
V
Y
N
N
E
E
Q
V
G
----
L
A
I
R
S
K
I
A
D
G
----
S
----
V
K
R
E
D
I
F
Y
T
S
K
L
W
S
N
S
H
R
P
E
L
V
R
P
A
L
E
R
S
L
K
N
L
Q
L
D
Y
V
D
L
Y
L
I
H
--
F
P
---
V
---
S
VKPGEEVIPKDENGKIL
F
D
T
V
D
L
---
C
-
A
--------
T
W
E
A
M
E
K
C
K
D
A
G
L
A
K
S
I
G
V
S
N
F
N
-
H
R
L
L
E
M
I
L
N
K
PGL
K
Y
K
P
V
C
N
Q
V
E
C
H
P
Y
F
N
Q
R
K
L
L
D
F
C
K
S
K
D
I
V
L
V
A
Y
S
A
L
-----
G
S
H
-----
R
-
E
-----
E
PWVDPNSPV
L
L
E
D
P
V
L
C
A
L
A
K
K
H
K
R
T
P
A
L
I
A
L
R
Y
Q
L
Q
R
G
V
V
V
L
A
K
S
Y
N
E
Q
R
I
R
Q
N
V
Q
V
F
E
F
Q
L
T
S
E
E
M
K
A
I
D
G
L
--------
N
R
N
------------------------
89
PsiBlast_CBE
83.83
32%
-95
- C7 -
4JQA
7
AK1C2_HUMAN
B:
[6-302]
-
Q
C
V
K
L
N
-
D
G
H
F
M
P
V
L
G
F
G
T
Y
A
P
A
E
V
P
K
S
K
A
L
E
A
V
K
L
A
I
E
A
G
F
H
H
I
D
S
A
H
V
Y
N
N
E
E
Q
V
G
----
L
A
I
R
S
K
I
A
D
G
----
S
----
V
K
R
E
D
I
F
Y
T
S
K
L
W
S
N
S
H
R
P
E
L
V
R
P
A
L
E
R
S
L
K
N
L
Q
L
D
Y
V
D
L
Y
L
I
H
--
F
P
---
V
---
S
VKPGEEVIPKDENGKIL
F
D
T
V
D
L
---
C
-
A
--------
T
W
E
A
M
E
K
C
K
D
A
G
L
A
K
S
I
G
V
S
N
F
N
-
H
R
L
L
E
M
I
L
N
K
PGL
K
Y
K
P
V
C
N
Q
V
E
C
H
P
Y
F
N
Q
R
K
L
L
D
F
C
K
S
K
D
I
V
L
V
A
Y
S
A
L
-----
G
S
H
-----
R
-
E
-----
E
PWVDPNSPV
L
L
E
D
P
V
L
C
A
L
A
K
K
H
K
R
T
P
A
L
I
A
L
R
Y
Q
L
Q
R
G
V
V
V
L
A
K
S
Y
N
E
Q
R
I
R
Q
N
V
Q
V
F
E
F
Q
L
T
S
E
E
M
K
A
I
D
G
L
--------
N
R
N
------------------------
117
HHSearch
83.70
40%
-88
- C7 -
3H7U
2
AKRC9_ARATH
A:
[26-308]
-
T
F
F
K
L
N
-
T
G
A
K
F
P
S
V
G
L
G
T
W
Q
A
S
P
---
G
L
V
G
D
A
V
A
A
A
V
K
I
G
Y
R
H
I
D
C
A
Q
I
Y
G
N
E
K
E
I
G
----
A
V
L
----
K
K
L
F
E
D
R
V
----
V
K
R
E
D
L
F
I
T
S
K
L
W
C
T
D
H
D
P
Q
D
V
P
E
A
L
N
R
T
L
K
D
L
Q
L
E
Y
V
D
L
Y
L
I
H
--
W
P
---
A
---
R
I
K
K
GSVGIKPENLLPV-----
D
I
---
P
-
S
--------
T
W
K
A
M
E
A
L
Y
D
S
G
K
A
R
A
I
G
V
S
N
F
S
T
K
K
L
A
D
L
L
E
L
A
---
R
V
P
P
A
V
N
Q
V
E
C
H
P
S
W
R
Q
T
K
L
Q
E
F
C
K
S
K
G
V
H
L
S
A
Y
S
P
L
-----
G
S
P
-----
G
-
T
TWLKS
D
---------
V
L
K
N
P
I
L
N
M
V
A
E
K
L
G
K
S
P
A
Q
V
A
L
R
W
G
L
Q
M
G
H
S
V
L
P
K
S
T
N
E
G
R
I
K
E
N
F
N
V
F
D
W
S
I
P
D
Y
M
F
A
K
F
A
E
I
--------
E
Q
A
------------------------
80
PsiBlast_CBE
83.65
32%
-95
- C7 -
2HDJ
5
AK1C2_HUMAN
A:
[6-302]
-
Q
C
V
K
L
N
-
D
G
H
F
M
P
V
L
G
F
G
T
Y
A
P
A
E
V
PK
S
K
A
L
E
A
V
K
L
A
I
E
A
G
F
H
H
I
D
S
A
H
V
Y
N
N
E
E
Q
V
G
----
L
A
I
R
S
K
I
A
D
G
----
S
----
V
K
R
E
D
I
F
Y
T
S
K
L
W
S
N
S
H
R
P
E
L
V
R
P
A
L
E
R
S
L
K
N
L
Q
L
D
Y
V
D
L
Y
L
I
H
--
F
P
---
V
---
S
V
K
P
G
EEV
I
P
K
D
ENGKIL
F
D
T
V
D
L
---
C
-
A
--------
T
W
E
A
M
E
K
C
K
D
A
G
L
A
K
S
I
G
V
S
N
F
N
-
H
R
L
L
E
M
I
L
N
K
PGL
K
Y
K
P
V
C
N
Q
V
E
C
H
P
Y
F
N
Q
R
K
L
L
D
F
C
K
S
K
D
I
V
L
V
A
Y
S
A
L
-----
G
S
H
-----
R
-
E
-----
E
PWVDPNSPV
L
L
E
D
P
V
L
C
A
L
A
K
K
H
K
R
T
P
A
L
I
A
L
R
Y
Q
L
Q
R
G
V
V
V
L
A
K
S
Y
N
E
Q
R
I
R
Q
N
V
Q
V
F
E
F
Q
L
T
S
E
E
M
K
A
I
D
G
L
--------
N
R
N
------------------------
79
PsiBlast_CBE
83.64
32%
-96
- C7 -
2HDJ
7
AK1C2_HUMAN
B:
[6-302]
-
Q
C
V
K
L
N
-
D
G
H
F
M
P
V
L
G
F
G
T
Y
A
P
A
E
V
PK
S
K
A
L
E
A
V
K
L
A
I
E
A
G
F
H
H
I
D
S
A
H
V
Y
N
N
E
E
Q
V
G
----
L
A
I
RSKI
A
D
G
----
S
----
V
K
R
E
D
I
F
Y
T
S
K
L
W
S
N
S
H
R
P
E
L
V
R
P
A
L
E
R
S
L
K
N
L
Q
L
D
Y
V
D
L
Y
L
I
H
--
F
P
---
V
---
S
VKPGEEVIPKDENGKILFDTV
D
L
---
C
-
A
--------
T
W
E
A
M
E
K
C
K
D
A
G
L
A
K
S
I
G
V
S
N
F
N
-
H
R
L
L
E
M
I
L
N
K
PGL
K
Y
K
P
V
C
N
Q
V
E
C
H
P
Y
F
N
Q
R
K
L
L
D
F
C
K
S
K
D
I
V
L
V
A
Y
S
A
L
-----
G
S
H
-----
R
-
E
-----
E
PWVDPNSPV
L
L
E
D
P
V
L
C
A
L
A
K
K
H
K
R
T
P
A
L
I
A
L
R
Y
Q
L
Q
R
G
V
V
V
L
A
K
S
Y
N
E
Q
R
I
R
Q
N
V
Q
V
F
E
F
Q
L
T
S
E
E
M
K
A
I
D
G
L
--------
N
R
N
------------------------
98
PsiBlast_CBE
83.62
32%
-94
* C7 *
4JQ1
4
AK1C2_HUMAN
A:
[6-302]
-
Q
C
V
K
L
N
-
D
G
H
F
M
P
V
L
G
F
G
T
Y
A
P
A
E
V
P
K
S
K
A
L
E
A
V
K
L
A
I
E
A
G
F
H
H
I
D
S
A
H
V
Y
N
N
E
E
Q
V
G
----
L
A
I
R
S
K
I
A
D
G
----
S
----
V
K
R
E
D
I
F
Y
T
S
K
L
W
S
N
S
H
R
P
E
L
V
R
P
A
L
E
R
S
L
K
N
L
Q
L
D
Y
V
D
L
Y
L
I
H
--
F
P
---
V
---
S
VKPGEEVIPKDENGKI
L
F
D
T
V
D
L
---
C
-
A
--------
T
W
E
A
M
E
K
C
K
D
A
G
L
A
K
S
I
G
V
S
N
F
N
-
H
R
L
L
E
M
I
L
N
K
PGL
K
Y
K
P
V
C
N
Q
V
E
C
H
P
Y
F
N
Q
R
K
L
L
D
F
C
K
S
K
D
I
V
L
V
A
Y
S
A
L
-----
G
S
H
-----
R
-
E
-----
E
PWVDPNSPV
L
L
E
D
P
V
L
C
A
L
A
K
K
H
K
R
T
P
A
L
I
A
L
R
Y
Q
L
Q
R
G
V
V
V
L
A
K
S
Y
N
E
Q
R
I
R
Q
N
V
Q
V
F
E
F
Q
L
T
S
E
E
M
K
A
I
D
G
L
--------
N
R
N
------------------------
95
PsiBlast_CBE
83.59
32%
-94
- C7 -
4JQ2
7
AK1C2_HUMAN
B:
[6-302]
-
Q
C
V
K
L
N
-
D
G
H
F
M
P
V
L
G
F
G
T
Y
A
P
A
E
V
P
K
S
K
A
L
E
A
V
K
L
A
I
E
A
G
F
H
H
I
D
S
A
H
V
Y
N
N
E
E
Q
V
G
----
L
A
I
R
S
K
I
A
D
G
----
S
----
V
K
R
E
D
I
F
Y
T
S
K
L
W
S
N
S
H
R
P
E
L
V
R
P
A
L
E
R
S
L
K
N
L
Q
L
D
Y
V
D
L
Y
L
I
H
--
F
P
---
V
---
S
VKPGEEV
I
P
K
D
ENGKIL
F
D
T
V
D
L
---
C
-
A
--------
T
W
E
A
M
E
K
C
K
D
A
G
L
A
K
S
I
G
V
S
N
F
N
-
H
R
L
L
E
M
I
L
N
K
PGL
K
Y
K
P
V
C
N
Q
V
E
C
H
P
Y
F
N
Q
R
K
L
L
D
F
C
K
S
K
D
I
V
L
V
A
Y
S
A
L
-----
G
S
H
-----
R
-
E
-----
E
PWVDPNSPV
L
L
E
D
P
V
L
C
A
L
A
K
K
H
K
R
T
P
A
L
I
A
L
R
Y
Q
L
Q
R
G
V
V
V
L
A
K
S
Y
N
E
Q
R
I
R
Q
N
V
Q
V
F
E
F
Q
L
T
S
E
E
M
K
A
I
D
G
L
--------
N
R
N
------------------------
97
PsiBlast_CBE
83.49
32%
-95
- C7 -
4JQ1
5
AK1C2_HUMAN
B:
[6-302]
-
Q
C
V
K
L
N
-
D
G
H
F
M
P
V
L
G
F
G
T
Y
A
P
A
E
V
PK
S
K
A
L
E
A
V
K
L
A
I
E
A
G
F
H
H
I
D
S
A
H
V
Y
N
N
E
E
Q
V
G
----
L
A
I
RSKI
A
D
G
----
S
----
V
K
R
E
D
I
F
Y
T
S
K
L
W
S
N
S
H
R
P
E
L
V
R
P
A
L
E
R
S
L
K
N
L
Q
L
D
Y
V
D
L
Y
L
I
H
--
F
P
---
V
---
S
VKPGEEVIPKDENGKILFDTV
D
L
---
C
-
A
--------
T
W
E
A
M
E
K
C
K
D
A
G
L
A
K
S
I
G
V
S
N
F
N
-
H
R
L
L
E
M
I
L
N
K
PGL
K
Y
K
P
V
C
N
Q
V
E
C
H
P
Y
F
N
Q
R
K
L
L
D
F
C
K
S
K
D
I
V
L
V
A
Y
S
A
L
-----
G
S
H
-----
R
-
E
-----
E
PWVDPNSPV
L
L
E
D
P
V
L
C
A
L
A
K
K
H
K
R
T
P
A
L
I
A
L
R
Y
Q
L
Q
R
G
V
V
V
L
A
K
S
Y
N
E
Q
R
I
R
Q
N
V
Q
V
F
E
F
Q
L
T
S
E
E
M
K
A
I
D
G
L
--------
N
R
N
------------------------
110
HHSearch
83.40
35%
-94
- C7 -
1S1P
3
AK1C3_HUMAN
A:
[6-308]
-
Q
C
V
K
L
N
-
D
G
H
F
M
P
V
L
G
F
G
T
Y
A
P
P
E
V
P
R
S
K
A
L
E
V
T
K
L
A
I
E
A
G
F
R
H
I
D
S
A
H
L
Y
N
N
E
E
Q
V
G
----
L
A
I
----
R
S
K
I
A
D
G
S
----
V
K
R
E
D
I
F
Y
T
S
K
L
W
S
T
F
H
R
P
E
L
V
R
P
A
L
E
N
S
L
K
K
A
Q
L
D
Y
V
D
L
Y
L
I
H
--
S
P
---
M
---
S
LKPGEEL
S
P
T
D
ENGKVI
F
D
I
V
D
L
---
C
-
T
--------
T
W
E
A
M
E
K
C
K
D
A
G
L
A
K
S
I
G
V
S
N
F
N
R
R
Q
L
E
M
I
L
N
K
P
GL-
K
Y
K
P
V
C
N
Q
V
E
C
H
P
Y
F
N
R
S
K
L
L
D
F
C
K
S
K
D
I
V
L
V
A
Y
S
A
L
-----
G
S
Q
-----
R
-
D
-----
K
RWVDPNSPV
L
L
E
D
P
V
L
C
A
L
A
K
K
H
K
R
T
P
A
L
I
A
L
R
Y
Q
L
Q
R
G
V
V
V
L
A
K
S
Y
N
E
Q
R
I
R
Q
N
V
Q
V
F
E
F
Q
L
T
A
E
D
M
K
A
I
D
G
L
--------
D
R
N
-
L
H
-
Y
F
N
S
----------------
92
PsiBlast_CBE
83.36
32%
-98
- C7 -
4JQ4
5
AK1C2_HUMAN
A:
[6-302]
-
Q
C
V
K
L
N
-
D
G
H
F
M
P
V
L
G
F
G
T
Y
A
P
A
E
V
P
K
S
K
A
L
E
A
V
K
L
A
I
E
A
G
F
H
H
I
D
S
A
H
V
Y
N
N
E
E
Q
V
G
----
L
A
I
R
S
K
I
A
D
G
----
S
----
V
K
R
E
D
I
F
Y
T
S
K
L
W
S
N
S
H
R
P
E
L
V
R
P
A
L
E
R
S
L
K
N
L
Q
L
D
Y
V
D
L
Y
L
I
H
--
F
P
---
V
---
S
VKPGEEVIPKDENGKIL
F
D
T
V
D
L
---
C
-
A
--------
T
W
E
A
M
E
K
C
K
D
A
G
L
A
K
S
I
G
V
S
N
F
N
-
H
R
L
L
E
M
I
L
N
K
PGL
K
Y
K
P
V
C
N
Q
V
E
C
H
P
Y
F
N
Q
R
K
L
L
D
F
C
K
S
K
D
I
V
L
V
A
Y
S
A
L
-----
G
S
H
-----
R
-
E
-----
E
PWVDPNSPV
L
L
E
D
P
V
L
C
A
L
A
K
K
H
K
R
T
P
A
L
I
A
L
R
Y
Q
L
Q
R
G
V
V
V
L
A
K
S
Y
N
E
Q
R
I
R
Q
N
V
Q
V
F
E
F
Q
L
T
S
E
E
M
K
A
I
D
G
L
--------
N
R
N
------------------------
90
PsiBlast_CBE
83.27
32%
-94
- C7 -
4JQA
5
AK1C2_HUMAN
A:
[6-302]
-
Q
C
V
K
L
N
-
D
G
H
F
M
P
V
L
G
F
G
T
Y
A
P
A
E
V
P
K
S
K
A
L
E
A
V
K
L
A
I
E
A
G
F
H
H
I
D
S
A
H
V
Y
N
N
E
E
Q
V
G
----
L
A
I
R
S
K
I
A
D
G
----
S
----
V
K
R
E
D
I
F
Y
T
S
K
L
W
S
N
S
H
R
P
E
L
V
R
P
A
L
E
R
S
L
K
N
L
Q
L
D
Y
V
D
L
Y
L
I
H
--
F
P
---
V
---
S
VKPGEEVIPKDENGKIL
F
D
T
V
D
L
---
C
-
A
--------
T
W
E
A
M
E
K
C
K
D
A
G
L
A
K
S
I
G
V
S
N
F
N
-
H
R
L
L
E
M
I
L
N
K
PGL
K
Y
K
P
V
C
N
Q
V
E
C
H
P
Y
F
N
Q
R
K
L
L
D
F
C
K
S
K
D
I
V
L
V
A
Y
S
A
L
-----
G
S
H
-----
R
-
E
-----
E
PWVDPNSPV
L
L
E
D
P
V
L
C
A
L
A
K
K
H
K
R
T
P
A
L
I
A
L
R
Y
Q
L
Q
R
G
V
V
V
L
A
K
S
Y
N
E
Q
R
I
R
Q
N
V
Q
V
F
E
F
Q
L
T
S
E
E
M
K
A
I
D
G
L
--------
N
R
N
------------------------
86
PsiBlast_CBE
83.22
32%
-94
- C7 -
4JTR
5
AK1C2_HUMAN
A:
[6-302]
-
Q
C
V
K
L
N
-
D
G
H
F
M
P
V
L
G
F
G
T
Y
A
P
A
E
V
PK
S
K
A
L
E
A
V
K
L
A
I
E
A
G
F
H
H
I
D
S
A
H
V
Y
N
N
E
E
Q
V
G
----
L
A
I
R
S
K
I
A
D
G
----
S
----
V
K
R
E
D
I
F
Y
T
S
K
L
W
S
N
S
H
R
P
E
L
V
R
P
A
L
E
R
S
L
K
N
L
Q
L
D
Y
V
D
L
Y
L
I
H
--
F
P
---
V
---
S
VKPGEEVIPKDENGKIL
F
D
T
V
D
L
---
C
-
A
--------
T
W
E
A
M
E
K
C
K
D
A
G
L
A
K
S
I
G
V
S
N
F
N
-
H
R
L
L
E
M
I
L
N
K
PGL
K
Y
K
P
V
C
N
Q
V
E
C
H
P
Y
F
N
Q
R
K
L
L
D
F
C
K
S
K
D
I
V
L
V
A
Y
S
A
L
-----
G
S
H
-----
R
-
E
-----
E
PWVDPNSPV
L
L
E
D
P
V
L
C
A
L
A
K
K
H
K
R
T
P
A
L
I
A
L
R
Y
Q
L
Q
R
G
V
V
V
L
A
K
S
Y
N
E
Q
R
I
R
Q
N
V
Q
V
F
E
F
Q
L
T
S
E
E
M
K
A
I
D
G
L
--------
N
R
N
------------------------
44
PsiBlast_CBE
83.21
34%
-88
- C7 -
3WBW
3
?
B:
[17-282]
---
I
S
F
H
-
D
G
H
T
M
P
Q
I
G
L
G
V
W
E
-
T
P
P
--
D
E
T
A
E
V
V
K
E
A
V
K
L
G
Y
R
S
V
D
T
A
R
L
Y
K
N
E
E
G
V
G
----
K
G
L
----
E
------------
D
H
P
E
I
F
L
T
T
K
L
W
N
D
E
Q
G
Y
D
S
T
L
R
A
Y
E
E
S
A
R
L
L
R
R
P
V
L
D
L
Y
L
I
H
--
W
P
---
M
PAQ
G
---------------------
Q
Y
---
V
-
E
--------
T
W
K
A
L
V
E
L
K
K
S
G
R
V
K
S
I
G
V
S
N
F
E
S
E
H
L
E
R
I
M
D
A
T
---
G
V
V
P
V
V
N
Q
I
E
L
H
P
D
F
Q
Q
R
A
L
R
E
F
H
E
K
H
N
I
R
T
E
S
W
R
P
L
-----
G
K
G
-----
R
-----------------
V
L
S
D
E
R
I
G
K
I
A
E
K
H
S
R
T
P
A
Q
V
V
I
R
W
H
L
Q
N
G
L
I
V
I
P
K
S
V
N
P
K
R
L
A
E
N
L
D
V
F
G
F
V
L
D
A
D
D
M
Q
A
I
E
Q
M
--------
D
R
K
D
G
R
-
M
G
--
A
D
P
N
T
A
K
F
--------
88
PsiBlast_CBE
83.20
32%
-96
- C7 -
4JTQ
4
AK1C2_HUMAN
A:
[6-302]
-
Q
C
V
K
L
N
-
D
G
H
F
M
P
V
L
G
F
G
T
Y
A
P
A
E
V
P
K
S
K
A
L
E
A
V
K
L
A
I
E
A
G
F
H
H
I
D
S
A
H
V
Y
N
N
E
E
Q
V
G
----
L
A
I
R
S
K
I
A
D
G
----
S
----
V
K
R
E
D
I
F
Y
T
S
K
L
W
S
N
S
H
R
P
E
L
V
R
P
A
L
E
R
S
L
K
N
L
Q
L
D
Y
V
D
L
Y
L
I
H
--
F
P
---
V
---
S
V
K
P
G
EEVIPKDENGKIL
F
D
T
V
D
L
---
C
-
A
--------
T
W
E
A
M
E
K
C
K
D
A
G
L
A
K
S
I
G
V
S
N
F
N
-
H
R
L
L
E
M
I
L
N
K
PGL
K
Y
K
P
V
C
N
Q
V
E
C
H
P
Y
F
N
Q
R
K
L
L
D
F
C
K
S
K
D
I
V
L
V
A
Y
S
A
L
-----
G
S
H
-----
R
-
E
-----
E
PWVDPNSPV
L
L
E
D
P
V
L
C
A
L
A
K
K
H
K
R
T
P
A
L
I
A
L
R
Y
Q
L
Q
R
G
V
V
V
L
A
K
S
Y
N
E
Q
R
I
R
Q
N
V
Q
V
F
E
F
Q
L
T
S
E
E
M
K
A
I
D
G
L
--------
N
R
N
------------------------
96
PsiBlast_CBE
83.18
32%
-96
- C7 -
4JQ2
5
AK1C2_HUMAN
A:
[6-302]
-
Q
C
V
K
L
N
-
D
G
H
F
M
P
V
L
G
F
G
T
Y
A
P
A
E
V
PK
S
K
A
L
E
A
V
K
L
A
I
E
A
G
F
H
H
I
D
S
A
H
V
Y
N
N
E
E
Q
V
G
----
L
A
I
R
S
K
I
A
D
G
----
S
----
V
K
R
E
D
I
F
Y
T
S
K
L
W
S
N
S
H
R
P
E
L
V
R
P
A
L
E
R
S
L
K
N
L
Q
L
D
Y
V
D
L
Y
L
I
H
--
F
P
---
V
---
S
VKPGEEVIPKDENGKIL
F
D
T
V
D
L
---
C
-
A
--------
T
W
E
A
M
E
K
C
K
D
A
G
L
A
K
S
I
G
V
S
N
F
N
-
H
R
L
L
E
M
I
L
N
K
PGL
K
Y
K
P
V
C
N
Q
V
E
C
H
P
Y
F
N
Q
R
K
L
L
D
F
C
K
S
K
D
I
V
L
V
A
Y
S
A
L
-----
G
S
H
-----
R
-
E
-----
E
PWVDPNSPV
L
L
E
D
P
V
L
C
A
L
A
K
K
H
K
R
T
P
A
L
I
A
L
R
Y
Q
L
Q
R
G
V
V
V
L
A
K
S
Y
N
E
Q
R
I
R
Q
N
V
Q
V
F
E
F
Q
L
T
S
E
E
M
K
A
I
D
G
L
--------
N
R
N
------------------------
94
PsiBlast_CBE
83.10
32%
-92
- C7 -
4JQ3
4
AK1C2_HUMAN
A:
[6-302]
-
Q
C
V
K
L
N
-
D
G
H
F
M
P
V
L
G
F
G
T
Y
A
P
A
E
V
P
K
S
K
A
L
E
A
V
K
L
A
I
E
A
G
F
H
H
I
D
S
A
H
V
Y
N
N
E
E
Q
V
G
----
L
A
I
R
S
K
I
A
D
G
----
S
----
V
K
R
E
D
I
F
Y
T
S
K
L
W
S
N
S
H
R
P
E
L
V
R
P
A
L
E
R
S
L
K
N
L
Q
L
D
Y
V
D
L
Y
L
I
H
--
F
P
---
V
---
S
V
K
P
G
EEVIPKDENGKIL
F
D
T
V
D
L
---
C
-
A
--------
T
W
E
A
M
E
K
C
K
D
A
G
L
A
K
S
I
G
V
S
N
F
N
-
H
R
L
L
E
M
I
L
N
K
PGL
K
Y
K
P
V
C
N
Q
V
E
C
H
P
Y
F
N
Q
R
K
L
L
D
F
C
K
S
K
D
I
V
L
V
A
Y
S
A
L
-----
G
S
H
-----
R
-
E
-----
E
PWVDPNSPV
L
L
E
D
P
V
L
C
A
L
A
K
K
H
K
R
T
P
A
L
I
A
L
R
Y
Q
L
Q
R
G
V
V
V
L
A
K
S
Y
N
E
Q
R
I
R
Q
N
V
Q
V
F
E
F
Q
L
T
S
E
E
M
K
A
I
D
G
L
--------
N
R
N
------------------------
93
PsiBlast_CBE
83.08
32%
-95
- C7 -
4JQ3
8
AK1C2_HUMAN
B:
[6-302]
-
Q
C
V
K
L
N
-
D
G
H
F
M
P
V
L
G
F
G
T
Y
A
P
A
E
V
P
K
S
K
A
L
E
A
V
K
L
A
I
E
A
G
F
H
H
I
D
S
A
H
V
Y
N
N
E
E
Q
V
G
----
L
A
I
R
S
K
I
A
D
G
----
S
----
V
K
R
E
D
I
F
Y
T
S
K
L
W
S
N
S
H
R
P
E
L
V
R
P
A
L
E
R
S
L
K
N
L
Q
L
D
Y
V
D
L
Y
L
I
H
--
F
P
---
V
---
S
VKPGEEV
I
P
K
D
ENGKIL
F
D
T
V
D
L
---
C
-
A
--------
T
W
E
A
M
E
K
C
K
D
A
G
L
A
K
S
I
G
V
S
N
F
N
-
H
R
L
L
E
M
I
L
N
K
PGL
K
Y
K
P
V
C
N
Q
V
E
C
H
P
Y
F
N
Q
R
K
L
L
D
F
C
K
S
K
D
I
V
L
V
A
Y
S
A
L
-----
G
S
H
-----
R
-
E
-----
E
PWVDPNSPV
L
L
E
D
P
V
L
C
A
L
A
K
K
H
K
R
T
P
A
L
I
A
L
R
Y
Q
L
Q
R
G
V
V
V
L
A
K
S
Y
N
E
Q
R
I
R
Q
N
V
Q
V
F
E
F
Q
L
T
S
E
E
M
K
A
I
D
G
L
--------
N
R
N
------------------------
100
PsiBlast_CBE
83.00
32%
-95
- C7 -
4L1X
4
AK1C2_HUMAN
A:
[8-304]
-
Q
C
V
K
L
N
-
D
G
H
F
M
P
V
L
G
F
G
T
Y
A
P
A
E
V
P
K
S
K
A
L
E
A
V
K
L
A
I
E
A
G
F
H
H
I
D
S
A
H
L
Y
N
N
E
E
Q
V
G
----
L
A
I
R
S
K
I
A
D
G
----
S
----
V
K
R
E
D
I
F
Y
T
S
K
L
W
S
N
S
H
R
P
E
L
V
R
P
A
L
E
R
S
L
K
N
L
Q
L
D
Y
V
D
L
Y
L
I
H
--
F
P
---
V
---
S
VKPGEEV
I
P
K
D
ENGKIL
F
D
T
V
D
L
---
C
-
A
--------
T
W
E
A
M
E
K
C
K
D
A
G
L
A
K
S
I
G
V
S
N
F
N
-
H
R
L
L
E
M
I
L
N
K
PGL
K
Y
K
P
V
C
N
Q
V
E
C
H
P
Y
F
N
Q
R
K
L
L
D
F
C
K
S
K
D
I
V
L
V
A
Y
S
A
L
-----
G
S
H
-----
R
-
E
-----
E
PWVDPNSPV
L
L
E
D
P
V
L
C
A
L
A
K
K
H
K
R
T
P
A
L
I
A
L
R
Y
Q
L
Q
R
G
V
V
V
L
A
K
S
Y
N
E
Q
R
I
R
Q
N
V
Q
V
F
E
F
Q
L
T
S
E
E
M
K
A
I
D
G
L
--------
N
R
N
------------------------
45
PsiBlast_CBE
82.54
34%
-90
- C7 -
3WBW
2
?
A:
[17-282]
---
I
S
F
H
-
D
G
H
T
M
P
Q
I
G
L
G
V
W
E
-
T
P
P
--
D
E
T
A
E
V
V
K
E
A
V
K
L
G
Y
R
S
V
D
T
A
R
L
Y
K
N
E
E
G
V
G
----
K
G
L
----
E
------------
D
H
P
E
I
F
L
T
T
K
L
W
N
D
E
Q
G
Y
D
S
T
L
R
A
Y
E
E
S
A
R
L
L
R
R
P
V
L
D
L
Y
L
I
H
--
W
P
---
M
PAQ
G
---------------------
Q
Y
---
V
-
E
--------
T
W
K
A
L
V
E
L
K
K
S
G
R
V
K
S
I
G
V
S
N
F
E
S
E
H
L
E
R
I
M
D
A
T
---
G
V
V
P
V
V
N
Q
I
E
L
H
P
D
F
Q
Q
R
A
L
R
E
F
H
E
K
H
N
I
R
T
E
S
W
R
P
L
-----
G
K
G
-----
R
-----------------
V
L
S
D
E
R
I
G
K
I
A
E
K
H
S
R
T
P
A
Q
V
V
I
R
W
H
L
Q
N
G
L
I
V
I
P
K
S
V
N
P
K
R
L
A
E
N
L
D
V
F
G
F
V
L
D
A
D
D
M
Q
A
I
E
Q
M
--------
D
R
K
D
G
R
-
M
G
--
A
D
P
N
T
A
K
F
--------
82
PsiBlast_CBE
82.37
32%
-93
- C7 -
1IHI
2
AK1C2_HUMAN
A:
[6-302]
-
Q
C
V
K
L
N
-
D
G
H
F
M
P
V
L
G
F
G
T
Y
A
P
A
E
V
P
K
S
K
A
L
E
A
V
K
L
A
I
E
A
G
F
H
H
I
D
S
A
H
V
Y
N
N
E
E
Q
V
G
----
L
A
I
R
S
K
I
A
D
G
----
S
----
V
K
R
E
D
I
F
Y
T
S
K
L
W
S
N
S
H
R
P
E
L
V
R
P
A
L
E
R
S
L
K
N
L
Q
L
D
Y
V
D
L
Y
L
I
H
--
F
P
---
V
---
S
VKPGEEV
I
P
K
D
ENGKIL
F
D
T
V
D
L
---
C
-
A
--------
T
W
E
A
M
E
K
C
K
D
A
G
L
A
K
S
I
G
V
S
N
F
N
-
H
R
L
L
E
M
I
L
N
K
PGL
K
Y
K
P
V
C
N
Q
V
E
C
H
P
Y
F
N
Q
R
K
L
L
D
F
C
K
S
K
D
I
V
L
V
A
Y
S
A
L
-----
G
S
H
-----
R
-
E
-----
E
PWVDPNSPV
L
L
E
D
P
V
L
C
A
L
A
K
K
H
K
R
T
P
A
L
I
A
L
R
Y
Q
L
Q
R
G
V
V
V
L
A
K
S
Y
N
E
Q
R
I
R
Q
N
V
Q
V
F
E
F
Q
L
T
S
E
E
M
K
A
I
D
G
L
--------
N
R
N
------------------------
81
PsiBlast_CBE
82.31
32%
-92
- C7 -
1IHI
2
AK1C2_HUMAN
B:
[6-302]
-
Q
C
V
K
L
N
-
D
G
H
F
M
P
V
L
G
F
G
T
Y
A
P
A
E
V
PK
S
K
A
L
E
A
V
K
L
A
I
E
A
G
F
H
H
I
D
S
A
H
V
Y
N
N
E
E
Q
V
G
----
L
A
I
RSKI
A
D
G
----
S
----
V
K
R
E
D
I
F
Y
T
S
K
L
W
S
N
S
H
R
P
E
L
V
R
P
A
L
E
R
S
L
K
N
L
Q
L
D
Y
V
D
L
Y
L
I
H
--
F
P
---
V
---
S
VKPGEEVIPKDENGKILFDTV
D
L
---
C
-
A
--------
T
W
E
A
M
E
K
C
K
D
A
G
L
A
K
S
I
G
V
S
N
F
N
-
H
R
L
L
E
M
I
L
N
K
PGL
K
Y
K
P
V
C
N
Q
V
E
C
H
P
Y
F
N
Q
R
K
L
L
D
F
C
K
S
K
D
I
V
L
V
A
Y
S
A
L
-----
G
S
H
-----
R
-
E
-----
E
PWVDPNSPV
L
L
E
D
P
V
L
C
A
L
A
K
K
H
K
R
T
P
A
L
I
A
L
R
Y
Q
L
Q
R
G
V
V
V
L
A
K
S
Y
N
E
Q
R
I
R
Q
N
V
Q
V
F
E
F
Q
L
T
S
E
E
M
K
A
I
D
G
L
--------
N
R
N
------------------------
91
PsiBlast_CBE
82.11
32%
-96
- C7 -
4JQ4
7
AK1C2_HUMAN
B:
[6-302]
-
Q
C
V
K
L
N
-
D
G
H
F
M
P
V
L
G
F
G
T
Y
A
P
A
E
V
P
K
S
K
A
L
E
A
V
K
L
A
I
E
A
G
F
H
H
I
D
S
A
H
V
Y
N
N
E
E
Q
V
G
----
L
A
I
R
S
K
I
A
D
G
----
S
----
V
K
R
E
D
I
F
Y
T
S
K
L
W
S
N
S
H
R
P
E
L
V
R
P
A
L
E
R
S
L
K
N
L
Q
L
D
Y
V
D
L
Y
L
I
H
--
F
P
---
V
---
S
VKPGEEV
I
P
K
D
ENGKIL
F
D
T
V
D
L
---
C
-
A
--------
T
W
E
A
M
E
K
C
K
D
A
G
L
A
K
S
I
G
V
S
N
F
N
-
H
R
L
L
E
M
I
L
N
K
PGL
K
Y
K
P
V
C
N
Q
V
E
C
H
P
Y
F
N
Q
R
K
L
L
D
F
C
K
S
K
D
I
V
L
V
A
Y
S
A
L
-----
G
S
H
--------------PWVDPNSPV
L
L
E
D
P
V
L
C
A
L
A
K
K
H
K
R
T
P
A
L
I
A
L
R
Y
Q
L
Q
R
G
V
V
V
L
A
K
S
Y
N
E
Q
R
I
R
Q
N
V
Q
V
F
E
F
Q
L
T
S
E
E
M
K
A
I
D
G
L
--------
N
R
N
------------------------
40
PsiBlast_CBE
80.68
36%
-101
- C7 -
3H7R
13
AKRC8_ARATH
A:
[25-292]
I
R
F
F
E
L
N
-
T
G
A
K
L
P
C
V
G
L
G
T
Y
A
M
V
A
T
--
A
-----
I
E
Q
A
I
K
I
G
Y
R
H
I
D
C
A
S
I
Y
G
N
E
K
E
I
G
G
V
L
K
K
L
I
----
G
D
G
----
F
----
V
K
R
E
E
L
F
I
T
S
K
L
W
S
N
D
H
L
P
E
D
V
P
K
A
L
E
K
T
L
Q
D
L
Q
I
D
Y
V
D
L
Y
L
I
H
--
W
P
---
A
---
S
LKKESLMPTPEMLTKP-----
D
I
---
T
-
S
--------
T
W
K
A
M
E
A
L
Y
D
S
G
K
A
R
A
I
G
V
S
N
F
S
S
K
K
L
T
D
L
L
N
V
A
---
R
V
T
P
A
V
N
Q
V
E
C
H
P
V
W
Q
Q
Q
G
L
H
E
L
C
K
S
K
G
V
H
L
S
G
Y
S
P
L
GSQSK
G
E
V
-----
R
-
L
-----
K
---------
V
L
Q
N
P
I
V
T
E
V
A
E
K
L
G
K
T
T
A
Q
V
A
L
R
W
G
L
Q
T
G
H
S
V
L
P
K
S
S
S
G
A
R
L
K
E
N
L
D
V
F
D
W
S
I
P
E
--------------------------------------------
41
PsiBlast_CBE
79.36
37%
-84
- C7 -
3H7U
2
AKRC9_ARATH
A:
[29-307]
----
K
L
N
-
T
G
A
K
F
P
S
V
G
L
G
T
W
Q
A
S
P
G
--
L
V
G
D
-
A
V
A
A
A
V
K
I
G
Y
R
H
I
D
C
A
Q
I
Y
G
N
E
K
E
I
G
A
V
L
K
K
L
F
----
E
D
R
----
V
----
V
K
R
E
D
L
F
I
T
S
K
L
W
C
T
D
H
D
P
Q
D
V
P
E
A
L
N
R
T
L
K
D
L
Q
L
E
Y
V
D
L
Y
L
I
H
--
W
P
---
A
---
R
I
K
K
GSVGIKPENLLPV-----
D
I
---
P
-
S
--------
T
W
K
A
M
E
A
L
Y
D
S
G
K
A
R
A
I
G
V
S
N
F
S
T
K
K
L
A
D
L
L
E
L
A
---
R
V
P
P
A
V
N
Q
V
E
C
H
P
S
W
R
Q
T
K
L
Q
E
F
C
K
S
K
G
V
H
L
S
A
Y
S
P
L
-----
G
S
P
GTTWL
K
-
S
-----
D
---------
V
L
K
N
P
I
L
N
M
V
A
E
K
L
G
K
S
P
A
Q
V
A
L
R
W
G
L
Q
M
G
H
S
V
L
P
K
S
T
N
E
G
R
I
K
E
N
F
N
V
F
D
W
S
I
P
D
Y
M
F
A
K
F
A
E
I
--------
E
Q
-------------------------