@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo2769: (2016-04-07 )
MKIRNLTKKMDDNLVLKDVSFDLKAGEITALIGRNGVGKTTLFSTMTGIYLPDEGDVFLDEESIFKHPEVKQQLFFLEDNMNHFNTYSVQTVVKIYRQIYTTFDEAFFNELMQQFELPMKAKLMSFSKGRKALFFIILAFSLNVRFLLLDEPLDGLDIIIKKQILATIKDTVKKRGTSVVIASHRLEELEAIADRVIVLKGASVELDYYLEDMRTDAVKIQVAFKTKKIPGFVKNNAQLLYRNGRIYTLLVTENASSFLAELRLEEPVLLEEMSISIEDIFTVHLANDKIDYYEI
Atome Classification :
(23 SA)
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.......---..10-.-.----.----......20........30........40........50.....--...60...-----..----.---------------..70...---......80.-.......----90..---------..-------....100---.----.-------------...---..110..----...-----..--120-....-----.-----....130.......140.......150.....---..160.......170.......180.......190....-...200-----.....-----....210.......220.......230.......240..--.....250.....--..260.......270.......280-----.........290...-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M
K
I
R
N
L
T
---
K
KM--D-D----
N
----
L
V
L
K
DV
S
F
D
LKA
G
E
I
T
A
L
IGRNGVGKT
T
L
F
S
T
M
T
G
I
Y
LPDEG
D
--
V
F
L
D
E
E
S
I-----FK----H---------------P
E
V
-
K
Q
Q
---
L
F
F
L
EDNMN-HF
N
T
Y
S
V
----
Q
T
V
V
---------
K
I
-------
Y
R
Q
I
Y
T
T
---
F
----
D
-------------
E
A
F
---
F
N
E
L
M
Q
Q
----FEL-----
P
M
--
K
---
A
K
L
M
-----
S
-----FSKG
R
K
A
L
F
F
I
I
L
A
FSL
N
V
R
F
L
L
LDEPLD
G
L
D
---
I
I
I
K
K
Q
I
L
A
T
I
K
D
T
V
K
KRG
T
S
V
V
I
A
S
H
R
L
E
E
L
E
A
I
AD
R
V
-
I
V
L
K-------GA
S
V
E
-----
L
D
Y
Y
L
E
DMRT
D
A
V
K
I
Q
V
A
F
KTKKIP
G
F
VKNN
A
Q
L
L
Y
RN
G
--
R
I
Y
T
L
L
VTEN
A
S
S
--
F
L
A
E
LRLEEP
V
L
L
E
E
MS
I
S
I
E
D
I
-------
F
T
V
H
LANDKIDYYEI-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
91.32
31%
-124
- C1 -
4WBS
1
?
B:
[42-256]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
R
N
L
K
---
K
R
Y
--
G
-
S
----
R
----
T
V
V
K
D
V
S
L
D
V
K
S
G
E
V
V
G
L
L
G
P
N
G
A
G
K
T
T
S
F
Y
M
I
V
G
L
V
P
L
D
A
G
E
--
I
D
L
D
G
K
S
I
-----
S
L
----
L
---------------
P
I
H
-
K
R
A
S
L
G
L
S
Y
L
P
Q
E
A
S
-
V
F
R
K
L
S
V
----
E
E
N
I
---------
R
A
-------
V
L
E
L
Q
V
G
---------GKRLS
K
D
A
I
A
S
R
T
E
A
L
---
L
D
E
L
--
Q
----
I
S
H
-----
L
R
--
E
---
N
P
A
L
-----
S
-----
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
T
N
P
S
F
I
L
L
D
E
P
F
A
G
V
D
---
P
I
A
V
L
E
I
Q
K
I
V
K
-
F
L
K
Q
R
N
I
G
V
L
I
T
D
H
N
V
R
E
T
L
G
I
C
D
H
A
-
Y
I
I
S
-------
D
G
S
V
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
87.74
31%
-125
- C1 -
4WBS
1
?
A:
[42-256]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
R
N
L
K
---
K
R
Y
--
G
-
S
----
R
----
T
V
V
K
D
V
S
L
D
V
K
S
G
E
V
V
G
L
L
G
P
N
G
A
G
K
T
T
S
F
Y
M
I
V
G
L
V
P
L
D
A
G
E
--
I
D
L
D
G
K
S
I
-----
S
L
----
L
---------------
P
I
H
-
K
R
A
S
L
G
L
S
Y
L
P
Q
E
A
S
-
V
F
R
K
L
S
V
----
E
E
N
I
---------
R
A
-------
V
L
E
L
Q
V
G
---
D
----
D
GKRLS
K
D
A
I
A
S
R
T
E
A
L
---
L
D
E
L
--
Q
----
I
S
H
-----
L
R
--
E
---
N
P
A
L
-----
S
-----
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
T
N
P
S
F
I
L
L
D
E
P
F
A
G
V
D
---
P
I
A
V
L
E
I
Q
K
I
V
K
-
F
L
K
Q
R
N
I
G
V
L
I
T
D
H
N
V
R
E
T
L
G
I
C
D
H
A
-
Y
I
I
S
-------
D
G
S
V
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
48
Fugue
82.78
26%
-118
- C1 -
3B60
2
MSBA_SALTY
A:
[10-581]
-----------------------------------------------------------------------------W
Q
T
F
R
R
L
W
P
T
I
A
PFK
A
G
L
I
V
A
G
I
A
L
I
L
N
A
A
S
D
T
F
M
L
S
L
LKPLLDDGFGKTDRSVLLW
M
P
L
V
V
I
G
L
M
I
L
R
G
I
T
S
Y
I
S
S
Y
C
I
S
W
V
S
G
K
V
V
M
T
M
R
R
R
L
F
G
H
M
M
G
MPVAFFDKQS
T
G
T
L
L
S
R
I
T
Y
D
S
E
Q
V
A
S
S
S
S
G
A
L
I
T
V
V
R
E
G
A
S
I
I
G
L
F
I
M
M
FYYS
W
Q
L
S
I
I
L
V
V
L
A
P
I
V
S
I
A
I
R
V
V
S
K
R
F
R
S
I
S
K
N
M
Q
N
T
M
G
Q
V
T
T
S
A
E
Q
M
L
K
G
H
KEVLIFGG
Q
E
V
E
T
K
R
F
D
K
V
S
N
K
M
R
L
Q
G
M
K
M
V
S
A
S
S
I
S
D
P
I
I
Q
L
I
A
S
L
A
L
A
F
V
L
Y
A
A
S
FPSVMDSLT
A
G
T
I
T
V
V
F
S
S
M
I
A
L
M
R
P
L
K
S
L
T
N
V
N
A
Q
F
Q
R
G
M
A
A
C
Q
T
L
F
A
I
L
D
SEQEK
D
E
G
K
RVIDRATGD
L
E
F
R
N
V
T
---
F
T
Y
PG
R
-
E
----
V
----
P
A
L
R
N
I
N
L
K
I
P
A
G
K
T
V
A
L
V
G
R
S
G
S
G
K
S
T
I
A
S
L
I
T
R
F
Y
D
I
D
E
G
H
--
I
L
M
D
G
H
D
L
RE---
Y
T
----
L
---------------
A
S
L
-
R
N
Q
---
V
A
L
V
S
Q
N
V
H
-
L
F
N
D
-
T
V
----
A
N
N
I
---------
A
Y
ARTEEYS
R
E
Q
I
E
E
A
---
A
----
R
-------------
M
A
Y
---
A
M
D
F
I
N
K
M
DNG
L
D
T
-----
I
I
--
G
---
E
N
G
V
-----
L
-----
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
L
R
D
S
P
I
L
I
L
D
E
A
T
S
A
L
D
---
T
E
S
E
R
A
I
Q
A
A
L
D
E
L
Q
K
N
R
-
T
S
L
V
I
A
-
H
R
L
S
T
I
E
Q
-
A
D
E
I
-
V
V
V
E
-------
D
G
I
I
V
-----
E
R
G
--------------------------
T
H
S
E
L
L
A
Q
H
G
--
V
Y
A
Q
L
H
K
M
Q
F
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
82.46
25%
-124
- C1 -
4RVC
-
?
A:
[4-222]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
E
V
K
D
L
S
---
G
G
Y
--
T
-
A
----
Q
----
N
V
L
E
D
V
T
F
V
V
D
R
G
E
M
V
A
L
I
G
L
N
G
A
G
K
S
T
T
I
K
H
I
I
G
L
M
E
P
R
R
G
A
--
I
S
I
N
G
Y
R
L
-----
A
D
----
G
---------------
P
E
T
Y
R
R
Q
---
F
A
Y
I
P
E
T
P
V
-
L
Y
E
E
L
T
L
----
E
E
H
L
---------
R
L
-------
A
A
M
A
Y
G
L
---
S
----
E
-------------
A
E
Y
E
R
R
L
P
P
L
L
R
E
----
F
R
L
---------
E
---
R
R
L
S
-----
S
FPAH-
F
S
K
G
M
K
Q
K
V
M
I
V
C
A
F
L
L
E
P
P
L
Y
I
I
D
E
P
F
L
G
L
D
---
P
L
A
I
H
A
L
L
E
R
M
N
E
Q
-
K
A
K
G
A
G
I
L
L
S
T
H
I
L
A
T
A
E
R
Y
C
D
S
F
-
V
I
L
H
-------
N
G
R
V
K
-----
A
K
G
T
L
D
D
I
R
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
HHSearch
82.12
25%
-117
- C1 -
3FVQ
3
FBPC_NEIG1
A:
[5-235]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
H
I
G
H
L
S
---
K
S
F
--
Q
-
N
----
T
----
P
V
L
N
D
I
S
L
S
L
D
P
G
E
I
L
F
I
I
G
A
S
G
C
G
K
T
T
L
L
R
C
L
A
G
F
E
Q
P
D
S
G
E
--
I
S
L
S
G
K
T
I
-----
F
S
----
K
N
T
N
L
-----------
P
V
R
-
E
R
R
---
L
G
Y
L
V
Q
E
G
V
-
L
F
P
H
L
T
V
----
Y
R
N
I
---------
A
Y
-------
G
L
G
N
G
K
G
RT
A
Q
----
E
-------------
R
Q
R
---
I
E
A
M
L
E
L
----
T
G
I
-----
S
E
--
L
AG-
R
Y
P
H
-----
E
-----
L
S
G
G
Q
Q
Q
R
A
A
L
A
R
A
L
A
P
D
P
E
L
I
L
L
D
E
P
F
S
A
L
D
---
E
Q
L
R
R
Q
I
R
E
D
M
I
A
A
L
R
A
N
G
K
S
A
V
F
V
S
H
D
R
E
E
A
L
Q
Y
A
D
R
I
-
A
V
M
K
-------
Q
G
R
I
L
-----
Q
T
A
S
P
H
E
L
Y
R
Q
P
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
HHSearch
81.97
24%
-122
- C1 -
3TUI
1
METN_ECOLI
C:
[25-254]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
K
L
S
N
I
T
---
K
V
F
--
H
-
Q
GTRT
I
----
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
--
V
L
V
D
G
Q
E
L
-----
T
T
----
L
SESEL----------
T
K
A
-
R
R
Q
---
I
G
M
I
F
Q
H
F
N
-
L
L
S
S
R
T
V
----
F
G
N
V
---------
A
L
-------
P
L
E
L
D
N
T
---
P
----
K
DEV----------
K
R
R
---
V
T
E
L
L
S
L
----
V
G
L
-----
G
D
--
K
HD-
S
Y
P
S
-----
N
-----
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
---
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
-
A
V
I
S
-------
N
G
E
L
I
-----
E
Q
D
T
V
S
E
V
F
S
H
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
HHSearch
81.77
24%
-115
- C1 -
1Z47
1
?
A:
[15-237]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
E
F
V
G
V
E
---
K
I
Y
--
P
G
G
----
A
----
R
S
V
R
G
V
S
F
Q
I
R
E
G
E
M
V
G
L
L
G
P
S
G
S
G
K
T
T
I
L
R
L
I
A
G
L
E
R
P
T
K
G
D
--
V
W
I
G
G
K
R
V
-----
T
D
----
L
---------------
P
P
Q
-
K
R
N
---
V
G
L
V
F
Q
N
Y
A
-
L
F
Q
H
M
T
V
----
Y
D
N
V
---------
S
F
-------
G
L
R
E
K
R
V
---
P
K
D
E
-
M
-------------
D
A
R
---
V
R
E
L
L
R
F
----
M
R
L
-----
E
S
--
Y
AN-
R
F
P
H
-----
E
-----
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
A
P
R
P
Q
V
L
L
F
D
E
P
F
A
A
I
D
---
T
Q
I
R
R
E
L
R
T
F
V
R
Q
V
H
D
E
M
G
V
T
S
V
F
V
T
H
D
Q
E
E
A
L
E
V
A
D
R
V
-
L
V
L
H
-------
E
G
N
V
E
-----
Q
F
G
T
P
E
E
V
Y
E
K
P
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
54
Fugue
81.63
20%
-107
- C1 -
4F4C
3
PGP1_CAEEL
A:
[4-1306]
N
G
S
L
R
Q
S
L
R
T
L
D
S
F
SLA
P
E
D
V
L
K
T
A
I
K
T
V
E
D
Y
EGDNIDSNG
E
I
K
I
TRDEVV
N
K
V
S
I
P
Q
L
Y
RYTT
T
L
E
K
L
L
L
F
I
G
T
L
V
A
V
I
T
G
A
G
L
P
L
M
S
I
L
Q
G
K
V
S
Q
A
F
I
N
E
Q
I
V
I
N
N
N
G
S
T
F
LPTGQNYT
K
T
D
F
E
H
D
V
M
N
V
V
W
S
Y
A
A
M
T
V
G
M
W
A
A
G
Q
I
T
V
T
C
Y
L
Y
V
A
E
Q
M
N
N
R
L
R
R
E
F
V
K
S
I
L
R
QE
I
S
W
F
D
T
N
HSGT
L
A
T
K
L
F
D
N
L
E
R
V
K
E
G
T
GD
K
I
G
M
A
F
Q
Y
L
S
Q
F
I
T
G
F
I
V
A
F
T
H
S
W
Q
L
T
L
V
M
L
A
V
T
P
I
Q
A
L
C
G
F
A
I
A
K
S
M
S
T
F
A
I
R
E
T
L
R
Y
A
K
A
G
K
V
V
E
E
T
I
S
S
I
R
T
V
V
S
L
NG
L
R
Y
E
L
E
R
Y
S
T
A
V
E
E
A
K
K
A
G
V
L
K
G
L
F
L
G
I
S
F
G
A
M
Q
A
S
N
F
I
S
F
A
L
A
F
Y
I
G
V
G
W
V
H
D
GSLN
F
G
D
M
L
T
T
F
S
S
V
M
M
G
S
M
A
L
G
L
A
G
P
Q
L
A
V
L
G
T
A
Q
G
A
A
S
G
I
Y
E
V
LDRKPVIDSS
S
K
A
G
R
KDMKIK
G
D
I
T
V
E
N
V
H
F
T
Y
P
S
R
--
P
-
D
----
V
----
P
I
L
R
G
M
N
L
R
V
N
A
G
Q
T
V
A
L
V
G
S
S
G
C
G
K
S
T
I
I
S
L
L
L
R
Y
Y
D
V
L
K
G
K
--
I
T
I
D
G
V
D
V
RD---
I
N
----
L
---------------
E
F
L
-
R
K
N
---
V
A
V
V
S
Q
E
P
A
-
L
F
N
C
T
I
E
----
E
N
I
S
L
G
KEGIT
R
E
E
M
-------
V
A
A
C
K
M
A
---
N
----
A
-------------
E
K
F
---
I
K
T
L
P
N
G
----
Y
N
T
-----
L
V
--
G
---
D
R
G
T
-----
Q
-----
L
S
G
G
Q
K
Q
R
I
A
I
A
R
A
L
V
R
N
P
K
I
L
L
L
D
E
A
T
S
A
L
D
---
A
E
S
E
G
I
V
Q
Q
A
L
D
K
A
A
K
G
R
--
T
T
I
I
I
A
H
R
L
S
T
I
R
N
-
A
D
L
I
-
I
S
C
K
-------
N
G
Q
V
V
-----
E
V
---------------------------
G
D
H
R
A
L
M
A
Q
Q
--
G
L
Y
Y
D
L
V
T
A
Q
T
F
T
--
D
A
V
D
S
A
A
E
G
E
R
I
G
K
D
A
L
S
R
L
K
Q
E
-------
L
E
E
N
N
A
Q
-
K
T
N
L
F
E
I
L
Y
H
A
RPH
A
L
S
L
F
I
G
M
S
T
A
T
I
G
G
F
I
Y
P
T
Y
S
V
F
F
T
S
F
M
N
V
F
AGNPADFL
S
Q
G
H
F
W
A
L
M
F
L
V
L
A
A
A
Q
G
I
C
S
F
L
M
T
F
F
M
G
I
A
S
E
S
L
T
R
D
L
R
N
K
L
F
R
N
V
L
S
QHIGFFDSPQNA
S
G
K
I
S
T
R
L
A
T
D
V
P
N
L
R
T
A
I
D
F
R
F
S
T
V
I
T
T
L
V
S
M
V
A
G
I
G
L
A
F
F
Y
G
W
Q
M
A
L
L
I
I
A
I
L
P
I
V
A
F
G
Q
Y
L
R
G
RRFTGKNVKSA
S
E
F
A
D
S
G
K
I
A
I
E
A
I
E
N
V
R
T
V
Q
A
L
AR
E
D
T
F
Y
E
N
F
C
E
K
L
D
I
P
H
K
E
A
I
K
E
A
F
I
Q
G
L
S
Y
G
C
A
S
S
V
L
Y
L
L
N
T
C
A
Y
R
M
G
L
A
L
I
I
TDPPTMQ
P
M
R
V
L
R
V
M
Y
A
I
T
I
S
T
S
TLGFAT
S
Y
F
P
E
Y
A
K
A
T
F
A
G
G
I
I
F
G
M
L
R
KISKIDSLSLAGEKKKLYGK
V
I
F
K
N
V
R
F
A
Y
PERPEIEILK
G
L
S
F
S
V
E
PG
Q
T
L
A
L
V
G
P
S
GCGKST
V
V
A
L
L
E
RFYDTL
G
G
E
I
F
I
DGSEIKTLN
P
E
H
T
R
S
Q
I
A
I
V
S
Q
E
P
T
L
F
DCS
I
A
E
N
I
I
YGLDPSSVT
M
A
Q
V
E
E
A
A
R
L
A
NI
H
N
F
I
A
E
LPEGFETRVGDRGTQLS
G
G
Q
K
Q
R
I
A
I
A
R
A
L
V
R
NPK
I
L
L
L
D
EATSALDT
E
S
E
K
V
V
Q
E
A
L
D
R
A
R
EG
R
T
C
I
V
I
A
HRLNTVMNAD
C
I
A
V
V
S
NGTII
E
K
G
T
H
T
Q
L
M
S
E
K
29
HHSearch
80.95
25%
-111
- C1 -
2IT1
-
?
A:
[4-224]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
K
L
E
N
I
V
---
K
K
F
--
G
-
N
----
F
----
T
A
L
N
N
I
N
L
K
I
K
D
G
E
F
M
A
L
L
G
P
S
G
S
G
K
S
T
L
L
Y
T
I
A
G
I
Y
K
P
T
S
G
K
--
I
Y
F
D
E
K
D
V
-----
T
E
----
L
---------------
P
P
K
-
D
R
N
---
V
G
L
V
F
Q
N
W
A
-
L
Y
P
H
M
T
V
----
Y
K
N
I
---------
A
F
-------
P
L
E
L
R
K
A
---
P
R
E
E
-
I
-------------
D
K
K
---
V
R
E
V
A
K
M
----
L
H
I
-----
D
K
--
L
LN-
R
Y
P
W
-----
Q
-----
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
V
K
E
P
E
V
L
L
L
D
E
P
L
S
N
L
D
---
A
L
L
R
L
E
V
R
A
E
L
K
R
L
Q
K
E
L
G
I
T
T
V
Y
V
T
H
D
Q
A
E
A
L
A
M
A
D
R
I
-
A
V
I
R
-------
E
G
E
I
L
-----
Q
V
G
T
P
D
E
V
Y
Y
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
41
HHSearch
79.85
24%
-126
- C1 -
3GFO
1
ECFA3_CLOP1
A:
[8-236]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
K
V
E
E
L
N
---
Y
N
Y
--
S
-
D
G---
T
----
H
A
L
K
G
I
N
M
N
I
K
R
G
E
V
T
A
I
L
G
G
N
G
V
G
K
S
T
L
F
Q
N
F
N
G
I
L
K
P
S
S
G
R
--
I
L
F
D
N
K
P
I
-----
D
Y
----
S
R
K
G
I
-----------
M
K
L
-
R
E
S
---
I
G
I
V
F
Q
D
P
D
N
Q
L
F
S
A
S
V
----
Y
Q
D
V
---------
S
F
-------
G
A
V
N
M
K
L
---
P
E
D
E
-
I
-------------
R
K
R
---
V
D
N
A
L
K
R
----
T
G
I
-----
E
H
LK
D
---
K
P
T
H
-----
C
-----
L
S
F
G
Q
K
K
R
V
A
I
A
G
V
L
V
M
E
P
K
V
L
I
L
D
E
P
T
A
G
L
D
---
P
M
G
V
S
E
I
M
K
L
L
V
E
M
Q
K
E
L
G
I
T
I
I
I
A
T
H
D
I
D
I
V
P
L
Y
C
D
N
V
-
F
V
M
K
-------
E
G
R
V
I
-----
L
Q
G
N
P
K
E
V
F
A
E
K
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
43
HHSearch
79.76
23%
-115
* C1 *
2OLJ
4
?
A:
[25-250]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
D
V
H
Q
L
K
---
K
S
F
--
G
-
S
----
L
----
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
--
I
I
I
D
G
I
N
L
-----
K
A
KDTN
L
---------------
N
K
V
-
R
E
E
---
V
G
M
V
F
Q
R
F
N
-
L
F
P
H
M
T
V
----
L
N
N
I
---------
T
L
-------
A
P
M
K
V
R
K
---
W
P
R
E
K
A
-------------
E
A
K
---
A
M
E
L
L
D
K
----
V
G
L
-----
K
D
--
K
AH-
A
Y
P
D
-----
S
-----
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
---
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
-
N
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
-
L
F
M
D
-------
G
G
Y
I
I
-----
E
E
G
K
P
E
D
L
F
D
R
P
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
78.66
31%
-111
- C1 -
4P32
2
LPTB_ECOLI
A:
[3-212]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
T
A
K
N
L
A
---
K
A
Y
--
K
-
G
----
R
----
R
V
V
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
I
I
I
D
D
D
D
I
S
L
-----
L
P
L
---
H
---------------
A
R
A
-
R
R
G
---
I
G
Y
L
P
Q
E
A
S
-
I
F
R
R
L
S
V
Y
D
N
L
M
A
V
L
---------
Q
I
-------
R
D
D
L
S
A
E
---
Q
----
R
-------------
E
D
R
---
A
N
E
L
M
E
E
----
F
H
I
-----
E
H
--
L
---
R
D
S
M
GQ---
S
-----
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
A
N
P
K
F
I
L
L
D
E
P
F
A
G
V
D
P
I
S
V
I
D
I
K
R
I
I
E
H
L
R
D
S
----
G
L
G
V
L
I
T
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
-------
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
78.48
24%
-115
- C1 -
3PUV
5
MALK_ECOLI
A:
[4-227]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
Q
L
Q
N
V
T
---
K
A
W
--
G
-
E
----
V
----
V
V
S
K
D
I
N
L
D
I
H
E
G
E
F
V
V
F
V
G
P
S
G
C
G
K
S
T
L
L
R
M
I
A
G
L
E
T
I
T
S
G
D
--
L
F
I
G
E
K
R
M
-----
N
D
----
T
---------------
P
P
A
-
E
R
G
---
V
G
M
V
F
Q
S
Y
A
-
L
Y
P
H
L
S
V
----
A
E
N
M
---------
S
F
-------
G
L
K
L
A
G
A
---
K
----
K
-------------
E
V
I
---
N
Q
R
V
N
Q
V
----
A
E
V
-----
L
Q
--
L
---
A
H
L
L
DRKPK
A
-----
L
S
G
G
Q
R
Q
R
V
A
I
G
R
T
L
V
A
E
P
S
V
F
L
L
D
E
P
L
S
N
L
D
---
A
A
L
R
V
Q
M
R
I
E
I
S
R
L
H
K
R
L
G
R
T
M
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
K
I
-
V
V
L
D
AGRVA
Q
V
G
K
P
L
E
-----
L
Y
H
Y
P
A
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
78.19
26%
-112
- C1 -
2IT1
-
?
A:
[4-212]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
K
L
E
N
I
V
---
K
K
F
--
G
-
N
----
F
----
T
A
L
N
N
I
N
L
K
I
K
D
G
E
F
M
A
L
L
G
P
S
G
S
G
K
S
T
L
L
Y
T
I
A
G
I
Y
K
P
T
S
G
K
--
I
Y
F
D
E
K
D
V
-----
T
E
----
L
---------------
P
P
K
-
D
R
N
---
V
G
L
V
F
Q
N
W
A
-
L
Y
P
H
M
T
V
----
Y
K
N
I
---------
A
F
-------
P
L
E
L
R
K
A
---
P
----
R
-------------
E
E
I
---
D
K
K
V
R
E
V
----
A
K
M
-----
L
H
--
I
---
D
K
L
L
-----
N
RYPWQ
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
V
K
E
P
E
V
L
L
L
D
E
P
L
S
N
L
D
---
A
L
L
R
L
E
V
R
A
E
L
K
R
L
Q
K
E
L
G
I
T
T
V
Y
V
T
H
D
Q
A
E
A
L
A
M
A
D
R
I
-
A
V
I
R
-------
E
G
E
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
44
HHSearch
78.12
20%
-116
- C1 -
1B0U
4
HISP_SALTY
A:
[7-244]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
H
V
I
D
L
H
---
K
R
Y
--
G
-
G
----
H
----
E
V
L
K
G
V
S
L
Q
A
R
A
G
D
V
I
S
I
I
G
S
S
G
S
G
K
S
T
F
L
R
C
I
N
F
L
E
K
P
S
E
G
A
--
I
I
V
N
G
Q
N
I
-----
N
L
----
V
R
D
KDGQLKVAD
K
N
Q
L
R
L
L
-
R
T
R
---
L
T
M
V
F
Q
H
F
N
-
L
W
S
H
M
T
V
----
L
E
N
V
---------
M
E
-------
A
P
I
Q
V
L
G
---
L
S
K
H
D
A
-------------
R
E
R
---
A
L
K
Y
L
A
K
----
V
G
I
-----
D
E
--
R
AQG
K
Y
P
V
-----
H
-----
L
S
G
G
Q
Q
Q
R
V
S
I
A
R
A
L
A
M
E
P
D
V
L
L
F
D
E
P
T
S
A
L
D
---
P
E
L
V
G
E
V
L
R
I
M
Q
Q
L
A
-
E
E
G
K
T
M
V
V
V
T
H
E
M
G
F
A
R
H
V
S
S
H
V
-
I
F
L
H
-------
Q
G
K
I
E
-----
E
E
G
D
P
E
Q
V
F
G
N
P
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
50
Fugue
77.68
20%
-112
- C1 -
3TUZ
3
METN_ECOLI
H:
[23-362]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HM
I
K
L
S
N
I
T
---
K
V
F
--
H
-
Q
----
G
TRTI
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
--
V
L
V
D
G
Q
E
L
TTLSE
S
E
----
L
---------------
T
K
A
-
R
R
Q
---
I
G
M
I
F
Q
H
F
N
-
L
L
S
S
R
T
V
----
F
G
N
V
---------
A
L
-------
P
L
E
L
D
N
T
---
P
----
K
-------------
D
E
V
---
K
R
R
V
T
E
L
----
L
S
L
VGLGD
K
H
--
D
---
S
Y
P
S
-----
N
-----
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
---
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
-
A
V
I
S
-------
N
G
E
L
I
EQDTV
S
E
V
F
S
H
P
K
T
P
L
A
Q
K
F
I
Q
S
T
L
H
L
D
I
P
E
D
Y
Q
E
R
L
Q
A
E
P
F
T
D
CV
P
M
L
R
L
E
F
T
G
Q
S
V
D
AP
L
L
S
E
T
A
R
R
F
N
V
N
N
N
I
I
S
A
Q
M
D
Y
A
GGVKFGI
M
L
T
E
M
H
G
T
Q
Q
D
T
Q
A
A
IAWLQEHHVKVEV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
77.62
24%
-114
- C1 -
3PUY
3
MALK_ECOLI
A:
[4-227]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
Q
L
Q
N
V
T
---
K
A
W
--
G
-
E
----
V
----
V
V
S
K
D
I
N
L
D
I
H
E
G
E
F
V
V
F
V
G
P
S
G
C
G
K
S
T
L
L
R
M
I
A
G
L
E
T
I
T
S
G
D
--
L
F
I
G
E
K
R
M
-----
N
D
----
T
---------------
P
P
A
-
E
R
G
---
V
G
M
V
F
Q
S
Y
A
-
L
Y
P
H
L
S
V
----
A
E
N
M
---------
S
F
-------
G
L
K
L
A
G
A
---
K
----
K
-------------
E
V
I
---
N
Q
R
V
N
Q
V
----
A
E
V
-----
L
Q
--
L
---
A
H
L
L
DRKPK
A
-----
L
S
G
G
Q
R
Q
R
V
A
I
G
R
T
L
V
A
E
P
S
V
F
L
L
D
E
P
L
S
N
L
D
---
A
A
L
R
V
Q
M
R
I
E
I
S
R
L
H
K
R
L
G
R
T
M
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
K
I
-
V
V
L
D
AGRVA
Q
V
G
K
P
L
E
-----
L
Y
H
Y
P
A
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
HHSearch
77.60
22%
-120
- C1 -
3RLF
3
MALK_ECOLI
A:
[4-225]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
Q
L
Q
N
V
T
---
K
A
W
--
G
-
E
----
V
----
V
V
S
K
D
I
N
L
D
I
H
E
G
E
F
V
V
F
V
G
P
S
G
C
G
K
S
T
L
L
R
M
I
A
G
L
E
T
I
T
S
G
D
--
L
F
I
G
E
K
R
M
-----
N
D
----
T
---------------
P
P
A
-
E
R
G
---
V
G
M
V
F
Q
S
Y
A
-
L
Y
P
H
L
S
V
----
A
E
N
M
---------
S
F
-------
G
L
K
L
A
G
A
---
K
K
E
V
-
I
-------------
N
Q
R
---
V
N
Q
V
A
E
V
----
L
Q
L
-----
A
H
--
L
LD-
R
K
P
K
-----
A
-----
L
S
G
G
Q
R
Q
R
V
A
I
G
R
T
L
V
A
E
P
S
V
F
L
L
D
E
P
L
S
N
L
D
---
A
A
L
R
V
Q
M
R
I
E
I
S
R
L
H
K
R
L
G
R
T
M
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
K
I
-
V
V
L
D
-------
A
G
R
V
A
-----
Q
V
G
K
P
L
E
L
Y
H
Y
P
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
77.57
31%
-107
- C1 -
4QC2
2
?
A:
[7-213]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
N
L
A
---
K
A
Y
--
K
-
G
----
R
----
R
V
V
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
I
I
I
D
D
D
D
I
S
L
-----
L
P
L
---
H
---------------
A
R
A
-
R
R
G
---
I
G
Y
L
P
Q
E
A
S
-
I
F
R
R
L
S
V
Y
D
N
L
M
A
V
L
---------
Q
I
-------
R
D
D
L
S
A
E
---
Q
----
R
-------------
E
D
R
---
A
N
E
L
M
E
E
----
F
H
I
-----
E
H
--
L
---
R
D
S
M
GQ---
S
-----
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
A
N
P
K
F
I
L
L
D
E
P
F
A
G
V
D
P
I
S
V
I
D
I
K
R
I
I
E
H
L
R
D
S
----
G
L
G
V
L
I
T
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
-------
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
77.56
31%
-110
- C1 -
4P32
2
LPTB_ECOLI
B:
[3-212]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
T
A
K
N
L
A
---
K
A
Y
--
K
-
G
----
R
----
R
V
V
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
II
I
D
D
D
D
I
S
L
-----
L
P
L---
H
---------------
A
R
A
-
R
R
G
---
I
G
Y
L
P
Q
E
A
S
-
I
F
R
R
L
S
V
YDNL
M
A
V
L
---------
Q
I
-------
R
D
D
L
S
A
E
---
Q
----
R
-------------
E
D
R
---
A
N
E
L
M
E
E
----
F
H
I
-----
E
H
--
L
---
R
D
S
M
GQ---
S
-----
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
A
N
P
K
F
I
L
L
D
E
P
F
A
G
V
D
PIS
V
I
D
I
K
R
I
I
E
H
L
R
D
S
----
G
L
G
V
L
I
T
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
-------
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
76.44
30%
-112
- C1 -
4P33
7
LPTB_ECOLI
A:
[3-212]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
T
A
K
N
L
A
---
K
A
Y
--
K
-
G
----
R
----
R
V
V
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
I
I
I
D
D
D
D
I
S
L
-----
L
P
L
---
H
---------------
A
R
A
-
R
R
G
---
I
G
Y
L
P
Q
E
A
S
-
I
F
R
R
L
S
V
Y
D
N
L
M
A
V
L
---------
Q
I
-------
R
D
D
L
S
A
E
---
Q
----
R
-------------
E
D
R
---
A
N
E
L
M
E
E
----
F
H
I
-----
E
H
--
L
---
R
D
S
M
GQ---
S
-----
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
A
N
P
K
F
I
L
L
D
Q
P
F
A
G
V
D
P
I
S
V
I
D
I
K
R
I
I
E
H
L
R
D
S
----
G
L
G
V
L
I
T
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
-------
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
76.22
31%
-103
- C1 -
4QC2
2
?
B:
[7-213]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
N
L
A
---
K
A
Y
--
K
-
G
----
R
----
R
V
V
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
II
I
D
D
D
D
I
S
L
-----
L
P
L---
H
---------------
A
R
A
-
R
R
G
---
I
G
Y
L
P
Q
E
A
S
-
I
F
R
R
L
S
V
YDNL
M
A
V
L
---------
Q
I
-------
R
D
D
L
S
A
E
---
Q
----
R
-------------
E
D
R
---
A
N
E
L
M
E
E
----
F
H
I
-----
E
H
--
L
---
R
D
S
M
GQ---
S
-----
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
A
N
P
K
F
I
L
L
D
E
P
F
A
G
V
D
PIS
V
I
D
I
K
R
I
I
E
H
L
R
D
S
----
G
L
G
V
L
I
T
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
-------
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
50.48
30%
-11
- C1 -
4P31
2
LPTB_ECOLI
A:
[3-212]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
T
A
K
N
L
A
---
K
A
Y
--
K
-
G
----
R
----
R
V
V
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
I
I
I
D
D
D
D
I
S
L
-----
L
P
L
---
H
---------------
A
R
A
-
R
R
G
---
I
G
Y
L
P
Q
E
A
S
-
I
F
R
R
L
S
V
Y
D
N
L
M
A
V
L
---------
Q
I
-------
R
D
D
L
S
A
E
---
Q
----
R
-------------
E
D
R
---
A
N
E
L
M
E
E
----
F
H
I
-----
E
H
LR
D
---
S
M
G
Q
-----
S
-----
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
A
N
P
K
F
I
L
L
D
E
P
F
A
G
V
D
PIS
V
I
D
I
K
R
I
I
E
H
L
R
D
S
----
G
L
G
V
L
I
T
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
-------
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------