@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu00430: (2016-06-01 )
MQFQIGDMVARKSYQMDVLFRIIGIEQTSKGNSIAILHGDEVRLIADSDFSDLVAVKKDEQMMRKKKDESRMNESLELLRQDYKLLREKQEYYATSQYQHQEHYFHMPGKVLHLDGDEAYLKKCLNVYKKIGVPVYGIHCHEKKMSASIEVLLDKYRPDILVITGHDAYSKQKGGIDDLNAYRHSKHFVETVQTARKKIPHLDQLVIFAGACQSHFESLIRAGANFASSPSRVNIHALDPVYIVAKISFTPFMERINVWEVLRNTLTREKGLGGIETRGVLRIGMPYKSN
Atome Classification :
(20 SA)
---------------------------...-----------......10---.........20........30......---..40.......--.50........60........70...-----.....80.......----.90..----......100......-.110...---.--...----120--.....----....130---........140.....----.-----.150.....--.-------.160....-.----.-------.170.-.......-.180----.--------......190--.......--.-200.......210.--.--.------...-.-.220.........230.......240.........250..-------------------------.....260.......270.......280.-......290--
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---------------------------MQF-----------Q
I
G
D
M
V
A
----
R
K
S
Y
Q
M
D
V
L
F
R
I
I
G
I
E
QTSKG
N
S
I
A
I
L
---HGD
E
V
R
L
I
ADS--D
F
S
D
L
V
AVK
K
D
E
Q
M
M
R
K
KK
D
E
S
R
M
N
E
-----
S
L
E
L
L
R
Q
D
Y
K
L
L
R
E
----
K
Q
E
Y
Y----ATSQYQHQE
H
Y
FHMP-
G
K
V
L
H
LD---G--
D
E
A
----
Y
----
L
K
K
C
L
----
N
V
Y
K
KI----GV
P
V
Y
G
I
H
C
H
E
K
K
M
S
A
----
S
-----
I
E
V
L
L
D
KYR--P-------
D
I
L
V
I
TGH-D----A-------YS--K-QKGGI
D
D
-
L
N
A
Y
----
R
--------
H
S
K
H
F
V
E
T
---
V
Q
T
A
R
K
K--I-P
H
L
D
Q
L
V
I
F
A
G
A
-
C
--
Q
--
S
------
H
F
E
-
S
-
L
I
--
R
AGANFASSP
S
R
V
N
I
H
ALD
P
--
V
Y
I
V
A
K
I
S
F
T
P
F
M
E
-------------------------
R
I
N
V
W
E
V
L
R
N
T
L
T
R
E
KGLGGIETR
G
V
L
R
I-GMPYKSN----
7
PsiBlast_PDB
68.98
24%
-36
- C2 -
3J16
-
DOM34_YEAST
A:
[35-271]
------------------------------------------------------------------------------------------------------
V
D
K
D
D
E
L
I
F
K
K
K
F
T
S
K
L
D
E
AGK
K
K
S
T
D
L
V
K
L
K
I
K
V
I
S
E
D
F
D
M
K
D
E
Y
L
K
Y
K
G
V
T
V
T
D
E
S
G
A
S
N
V
D
I
P
V
G
K
Y
L
S
F
T
---
L
--
D
Y
V
----
Y
P
F
T
I
I
K
Q
N
F
----
N
K
F
M
Q
-------
K
L
L
N
E
A
C
N
I
E
Y
K
S
D
----
T
-----
A
A
V
V
L
Q
E
G
I
--
A
-------
H
V
C
L
V
T
S
S
-
S
----
T
ILKQKIE
Y
S
MP
K
-
K
K
R
T
T
D
V
-
L
K
F
D
----
E
--------
K
T
E
K
F
Y
K
A
---
I
Y
S
A
M
K
K
--
D
-
L
N
F
D
K
L
K
T
I
I
-
L
-
C
--
S
--
P
------
G
F
Y
-
A
-
K
I
--
L
M
D
K
I
F
Q
Y
A
E
E
E
H
N
K
K
I
L
D
N
KG
M
F
F
I
A
H
C
S
-
T
G
Y
L
Q
-------------------------
G
I
N
--
E
V
L
K
N
P
L
Y
A
S
K
-------------------------
38
Fugue
64.40
18%
-30
- C3 -
4DO7
2
?
A:
[3-289]
--------------------ALRIDS
H
Q
H
F
W
RYRAADYPWI
G
A
G
M
G
V
L
----
A
R
D
Y
L
P
D
A
L
H
P
L
M
H
A
Q
--
A
L
G
A
S
I
A
V
Q
ARA
G
R
D
E
T
A
F
L
L
E
L
A
C
D
E
A
R
I
A
A
V
V
G
W
E
D
L
-
R
A
P
Q
L
A
E
R
V
A
E
WRGT-
K
L
R
G
F
R
H
Q
L
Q
D
E
A
D
----
V
R
A
F
V
----
D
D
A
D
F
A
R
G
V
A
W
L
Q
A
N
-
D
Y
V
Y
D
V
L
---
V
--
F
E
R
----
Q
----
L
P
D
V
Q
----
A
F
C
A
R
H
----
D
A
H
W
L
V
L
D
H
A
G
K
P
A
L
A
----
E
-----
F
D
T
A
L
A
R
W
R
--
A
-------
A
L
R
E
L
A
A
L
P
H
----
V
-------
V
C
--
K
-
L
S
G
L
V
T
E
-
A
D
W
R
----
R
--------
G
L
R
-----------------------------
A
S
-
D
--
L
--
R
------
H
I
E
-
Q
-
C
L
--
D
A
A
L
D
A
F
G
-
P
Q
R
L
M
F
G
S
D
W
P
--
V
C
L
L
A
A
-
S
Y
D
E
V
A
S
-------------------------
L
V
E
R
W
A
E
S
R
L
S
A
A
E
R
S
A
L
W
G
---
G
T
A
A
R
C
Y
A
L
P
--------
35
Fugue
64.34
18%
-58
* C3 *
4OJV
4
PDE1_YEAST
A:
[1-369]
MVV
F
E
I
T
ILGANGGPTEYG
T
Q
C
F
I
L
K
P
A
R
T
-----------
E
D
P
E
L
I
A
VDGG
A
G
M
Y
Q
L
R
E
M
L
V
Q
G
D
D
E
L
V
P
---
S
F
Y
E
H
---
D
R
E
P
I
E
F
F
I
D
S
--
K
L
N
--
I
Q
K
G
L
S
K
S
L
L
Q
S
L
K
R
Q
G
E
H
F
E
-----
S
A
N
T
M
K
K
T
Y
E
V
F
Q
G
----
I
T
D
Y
Y
----
I
T
--
H
P
H
L
D
H
I
S
G
L
V
-
V
N
S
P
S
I
Y
---
E
--
Q
E
N
----
S
----
K
K
K
T
I
W
G
L
P
H
T
I
D
V
L
----
Q
K
H
V
F
N
D
L
I
W
P
D
L
T
A
E
----
R
SRK
L
K
L
K
C
L
N
P
K
E
V
--
Q
KCTIFP
W
D
V
I
P
F
K
V
H
-
H
----
G
-------
I
G
--
V
-
K
T
G
A
P
V
Y
-
S
T
F
Y
I
F
R
D
R
--------
K
S
K
D
C
I
I
V
C
G
D
V
E
Q
D
R
R
E
SE
E
-
S
L
L
E
E
F
W
S
Y
V
A
E
-
N
IP
L
--
V
------
H
L
K
G
I
-
L
V
--
E
C
S
C
P
L
S
S
K
P
E
Q
L
Y
G
H
-
L
S
P
--
I
Y
L
I
N
E
L
S
N
L
N
T
L
Y
NSSKGLSG
L
N
V
I
V
T
H
V
K
S
T
PAKRD
P
R
L
T
I
L
E
E
L
R
-
F
L
A
E
E
R
N
L
G
D
------
L
R
I
-
S
I
A
L
E
G
H
T
L
F
L
2
PsiBlast_PDB
62.56
28%
-76
- C2 -
1MXS
1
ALKD_PSEPU
A:
[16-106]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
A
----
R
-----
I
D
A
I
C
E
K
A
R
IL
P
-------
V
I
T
I
A
R
E
E
-
D
I
L
P
L
A
-------
D
A
--
L
-
A
A
G
G
I
R
T
-
L
E
V
T
----
L
--------
R
S
Q
H
G
L
K
A
---
I
Q
V
L
R
E
Q
--
R
-
P
---
E
L
C
V
G
A
G
T
-
V
LD
R
--
S
------
M
F
A
-
A
-
V
E
--
A
A
G
A
Q
F
V
V
T
P
G
-------------------------------------------------------------------------------------------
25
HHSearch
59.31
16%
-73
- C2 -
3BO9
5
?
A:
[120-207]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
K
E
N
----
G
T
K
V
I
P
V
V
A
S
----
D
S
----
L
-----
A
-
R
M
V
E
R
A
G
--
A
-------
D
A
V
I
A
E
G
M
-
E
----
S
-------
G
G
--
H
-
I
-
G
E
-----------------------
V
T
T
F
V
L
---
V
N
K
V
S
R
S
------
V
N
I
P
V
I
A
A
G
G
-
I
--
A
--
D
G
R
----
G
M
A
-
A
-
A
F
--
A
L
G
A
E
A
V
Q
M
G
T
R
------------------------------------------------------------------------------------------
21
HHSearch
55.62
15%
-83
- C2 -
4HH3
-
?
C:
[290-395]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
A
L
A
A
----
E
M
L
R
A
V
----
G
W
S
T
S
V
V
H
P
---
E
S
V
A
----
A
-----
L
A
A
R
L
K
T
S
R
--
T
-------
S
T
L
V
V
A
P
S
-
L
----
L
-------
E
G
--
T
-
E
------------------------
Q
E
A
D
T
L
R
F
---
V
S
A
L
R
A
R
--
T
-
D
L
P
G
L
S
I
L
V
G
G
R
-
L
--
A
--
Q
------
L
P
P
-
S
K
L
K
--
D
S
G
A
D
A
G
F
A
H
L
A
L
L
P
A
A
L
A
-----------------------------------------------------------------------------------
23
HHSearch
55.48
16%
-86
- C2 -
4Z0G
4
?
A:
[163-301]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
V
V
V
L
D
SSQ
G
--
N
S
V
----
F
----
Q
I
N
M
I
----
K
W
I
K
E
T
FP--
D
L
Q
V
I
A
G
N
V
V
T
R
---
E
----
Q
-----
A
-
A
S
L
I
H
A
G
--
A
-------
D
G
L
R
I
G
M
G
-
S
----
G
-------
S
I
--
C
-
I
T
Q
E
V
M
A
-
C
-----------------
G
R
P
Q
G
T
A
---
V
Y
N
V
T
Q
F
--
A
-
N
Q
F
G
V
P
C
I
A
D
G
G
-
V
--
Q
N
I
G
------
H
I
T
-
K
-
A
I
--
A
L
G
A
S
T
V
M
M
G
G
-------------------------------------------------------------------------------------------
32
HHSearch
55.08
11%
-123
- C2 -
3FFS
-
IMDH_CRYPV
A:
[157-313]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
D
V
I
V
L
D
---
S
--
A
H
G
HS
L
N
I
----
I
R
T
L
K
----
E
I
K
S
K
M
----
N
I
D
V
I
V
G
N
V
V
---
T
E
E
----------
A
T
K
E
L
I
E
N
G
--
A
-------
D
G
I
K
V
G
I
-----------------------------
I
V
A
G
----
V
---------
G
V
P
Q
I
T
A
---
I
E
K
C
S
S
V
--
A
-
S
K
F
G
I
P
I
I
A
D
G
G
-
I
--
R
Y
S
G
------
D
I
G
-
K
-
A
L
--
A
V
G
A
S
S
V
M
I
G
S
I
L
-----------------------------------------------------------------------------------------
15
HHSearch
54.35
15%
-63
- C2 -
3F4W
1
?
A:
[79-198]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
-
Y
V
T
V
L
G
V
---
T
--
D
V
L
----
T
----
I
Q
S
C
I
----
R
A
A
K
E
A
----
G
K
Q
V
V
V
D
M
I
C
V
D
-
D
L
P
----
A
-----
R
V
R
L
L
E
E
A
G
--
A
-------
D
M
L
A
V
H
T
G
--------------
T
D
--
Q
-
Q
A
---
A
G
-
R
------------------
K
P
I
D
D
L
---
I
T
M
L
K
V
---
R
-
R
--
K
A
R
I
A
V
A
G
G
-
I
S-
S
--
Q
------
T
V
K
-
D
-
Y
A
--
L
L
G
P
D
V
V
I
V
G
-
S
A
I
T
H
A
A
D
P
--
A
G
------------------------------------------------------------------------------
31
HHSearch
52.98
17%
-74
- C2 -
4Z87
2
?
A:
[276-415]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
V
V
L
D
SSQ
G
--
N
S
V
----
F
----
Q
I
N
M
I
----
K
W
I
K
E
T
FP--
D
L
Q
V
I
A
G
N
V
V
T
---
R
-----
E
-----
Q
A
A
S
L
I
H
A
G
--
A
-------
D
G
L
R
I
G
M
G
-
S
----
G
-------
S
I
--
C
-
I
T
Q
E
V
M
A
---
C
G
----
R
--------
P
Q
---
G
T
A
---
V
Y
N
V
T
Q
F
--
A
-
N
Q
F
G
V
P
C
I
A
D
G
G
-
V
--
Q
N
I
G
------
H
I
T
-
K
-
A
I
--
A
L
G
A
S
T
V
M
M
G
--------------------------------------------------------------------------------------------
19
HHSearch
52.02
11%
-82
- C2 -
3VE9
1
?
A:
[80-196]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
I
A
H
A
F
---
V
--
G
V
E
----
G
----
S
L
A
S
L
----
S
--
Q
R
V
----
D
L
F
L
V
L
S
M
S
H
-
P
G
W
N
D
AF
Y
P
Y
-----
L
R
E
V
A
R
R
V
N
--
P
-------
K
G
F
V
A
-------------------------------------------------
P
A
T
R
P
S
M
---
I
S
R
V
K
G
D
--
F
-
P
---
D
K
L
V
I
S
P
G
-
V
--
G
--
T
QGA---
K
P
G
-
I
-
A
L
--
C
H
G
A
D
Y
E
I
V
G
R
S
-
V
Y
Q
S
A
D
P
--
V
R
K
L
E
E
I
-------------------------------------------------------------------------
28
HHSearch
48.54
15%
-42
- C2 -
1I4N
1
TRPC_THEMA
A:
[136-243]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
E
----
Q
----
I
K
E
I
Y
----
E
A
A
E
E
L
----
G
M
D
S
L
V
----
E
V
H
S
R
E
----
D
-----
L
E
K
V
F
S
V
I
R
--
P
-------
K
I
I
G
I
N
T
R
-
D
----
L
-------
D
T
--
F
-
E
----
I
K
-----------------------
K
N
V
---
L
W
E
L
L
P
L
--
V
-
P
-
D
D
T
V
V
V
A
E
S
G
-
I
--
K
DP
R
------
E
L
K
-
D
-
L
R
---
G
K
V
N
A
V
L
V
G
T
S
I
-
M
K
A
E
N
P
--
R
R
F
L
----------------------------------------------------------------------------
26
HHSearch
47.52
15%
-51
- C2 -
1P0K
1
IDI2_BACSU
A:
[177-285]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
----
S
V
P
V
I
V
K
E
V
G
F
G
M
S
K
-----
A
-----
S
A
G
K
L
Y
E
A
G
--
A
-------
A
A
V
D
I
G
G
--------------------------------------R
Q
I
S
F
F
NS
W
G
I
S
T
A
A
S
---
L
A
E
I
R
S
E
--
F
-
P
--
A
S
T
M
I
A
S
G
G
-
L
--
Q
--
D
A
L
----
D
V
A
-
K
-
A
I
--
A
L
G
A
S
C
T
G
M
A
G
H
F
L
K
---------------------------------------------------------------------------------------
12
HHSearch
46.28
9%
-64
- C2 -
1CCW
1
GMSS_CLOCO
A:
[27-118]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
T
N
A
----
G
F
N
V
V
N
I
G
V
--
L
S
P
Q
E
----
L
-----
F
I
K
A
A
I
E
T
K
--
A
-------
D
A
I
L
V
S
S
L
-
Y
----
G
-------
Q
G
--
E
----------------------------
I
D
C
K
G
L
---
R
Q
K
C
D
E
A
--
G
-
L
E
-
G
I
L
L
Y
V
G
G
N
I
V
--
V
--
G
KQH
W
P
D
V
E
K
-
R
-
F
K
--
D
M
G
Y
D
R
V
Y
A
---------------------------------------------------------------------------------------------
16
HHSearch
46.08
16%
-52
- C2 -
4R3U
1
?
C:
[26-106]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
D
---
G
--
H
D
R
----
G
----
V
K
V
V
A
----
R
A
L
R
D
A
----
G
M
D
V
I
Y
S
G
L
--
H
R
T
P
E
----
E
-----
V
V
N
T
A
I
Q
E
D
--
V
-------
D
V
L
G
V
S
L
L
-
S
----
G
-------
V
Q
------------------------------
L
T
V
F
P
K
I
---
F
K
L
L
D
E
R
--
G
A
G
--
D
L
I
V
I
A
G
G
V
------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
45.38
12%
-46
- C2 -
4N6F
2
?
A:
[121-219]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
N
A
----
G
----
T
V
E
A
A
----
R
E
L
R
A
E
----
G
M
E
L
L
P
F
I
L
P
D
---
L
A
----------
T
A
R
A
L
E
E
A
G
--
C
-------
A
A
L
R
V
M
A
S
-
P
----
V
-------
A
S
--
G
-
R
------------------------
G
-
I
A
N
P
A
A
---
I
R
E
L
I
E
Q
------
I
G
I
P
V
V
V
E
G
G
-
I
--
G
S
A
R
------
H
V
A
-
E
-
A
M
--
E
L
G
A
S
A
T
L
V
N
T
A
------------------------------------------------------------------------------------------
24
HHSearch
45.21
12%
-65
- C2 -
4X3Z
3
?
A:
[149-266]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
L
E
I
I
G
G
N
V
A
T
---
A
E
----
G
-----
A
-
R
A
L
I
E
A
G
--
V
-------
S
A
V
K
V
G
I
G
-
P
----
G
-------
S
I
--
C
-
T
T
----
R
-
I
V
T
G
----
V
--------
G
V
-
P
Q
I
T
A
---
I
A
D
A
A
G
V
--
A
-
N
E
Y
G
I
P
V
I
A
D
G
G
-
I
--
R
F
S
G
------
D
I
S
-
K
-
A
I
--
A
A
G
A
S
C
V
M
V
G
S
M
F
A
G
T
E
E
A
P
----------------------------------------------------------------------------------
17
HHSearch
44.68
10%
-65
- C2 -
1REQ
-
MUTA_PROFR
B:
[527-618]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
G
F
S
S
----
P
V
W
H
I
A
----
G
I
D
T
P
Q
V
E
--
G
G
-
T
T
A
----
E
-----
I
V
E
A
F
K
K
S
G
--
A
-------
Q
V
A
D
L
C
S
S
-
A
----
K
-------
V
Y
--
A
-
Q
---------------------------
Q
G
L
E
V
---
A
K
A
L
K
A
A
--
G
---
A
-
K
A
L
Y
L
S
G
A
-
F
--
K
--
E
------
F
G
D
-
D
-
A
A
E
A
E
K
L
I
D
G
R
L
F
M
--------------------------------------------------------------------------------------------
8
PsiBlast_PDB
42.74
23%
-56
- C2 -
4J9V
2
?
A:
[90-185]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
N
T
P
-
N
R
V
A
R
I
R
---
S
--
P
E
-----
Y
----
L
A
E
K
E
----
A
L
F
K
S
G
----
A
I
P
V
D
H
L
I
A
P
E
E
L
V
T
S
----
Y
-----
I
E
R
L
I
-
Q
Y
P
--
G
-------
A
L
Q
V
V
S
----------------
F
A
--
E
-
Q
K
V
S
L
V
A
-
V
K
A
Y
----
Y
--------
G
G
P
L
V
G
N
A
---
L
S
A
L
R
E
H
--
M
-
P
H
I
D
T
R
V
-----------------------------------------------------------------------------------------------------------------------------------
18
HHSearch
42.30
9%
-25
- C2 -
3MVN
-
?
A:
[325-452]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
-
N
I
T
V
Y
D
D
---
F
AH
H
P
T
----
A
----
I
T
A
T
I
----
D
A
L
R
A
K
V
GQQ
R
I
L
A
V
L
E
P
R
-----
K
H
----
E
-----
L
A
T
S
L
Q
--
D
--
A
-------
D
S
V
F
I
Y
Q
P
------------------
W
Q
V
S
E
V
L
A
N
L
A
Q
P
A
----
I
--------
S
A
D
D
V
D
E
L
---
V
M
R
I
V
Q
Q
--
A
--
K
P
N
D
H
I
L
I
M
S
N
-
G
--
A
--
F
GG----
I
H
Q
-
K
-
L
L
--
T
A
L
A
--------------------------------------------------------------------------------------------------