@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Wbm0790: (2015-12-04 )
MMLDKENPIIKEFEEAGAILHGHFVLSSGLHSDTYTQCAKIFENPSRAMKVCELLANKIKKELNSSIDLILSPAIGGIIVGYEIGRQLRMKTMFCERVNGKFELRRGFEIKRGEKILLVEDVITTGKSSLEAVKCAEDMGGKVVAEASLIKRNSETKLPFSIISLLELSIKNYSEAELPEELKKLPIIKPGSREYLSNCSK
Atome Classification :
(20 SA)
----------------------------------------------------------------------.........10........20---......----..30........40........50........60..-.-.....70........80.......------.90--------.......--.---.---------------------100------------.------------------.......--------------.--110.......120.......130.......140..-------------.....150-..------------..--.---------------.-------.-------..--160----------.........-170.-.......180.......190.......200
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----------------------------------------------------------------------MMLDKEN
P
I
I
K
E
F
E
EA
G
A
I
L
H
---
G
H
F
V
LS----SGLHS
D
T
Y
T
Q
C
A
K
I
FEN
P
S
R
A
M
K
V
C
E
L
L
A
N
K
I
K
K
E
L
-N-SSI
D
L
I
LSPAI
G
G
I
I
V
G
Y
E
I
G
R
Q
L
------
R
M
---------
K
T
M
F
C
E
R--V---N---------------------G--------------
K
------------------
F
E
L
RRGF--------------E--IKRG
E
K
I
L
L
V
E
D
V
I
TTGKS
S
L
E
A
V
K
C
A
E
DMG
G
K
V
V
-------------
A
E
A
S
L
I---KR------------NS--E---------------T-------K-------L
P
--
F
------------
S
I
I
S
L
L
E
L
S
-I-KN-Y
S
E
A
E
L
P
E
E
L
K
KLPIIKPG
S
R
E
Y
L
S
NCSK
65
Fugue
95.27
39%
-98
- C4 -
4PAW
3
PYRE_HELPY
A:
[22-218]
---------------------------------------------------------------------------
H
M
D
I
K
A
C
Y
Q
N
A
K
A
L
L
E
---
G
H
F
L
L
S
----
S
G
F
H
S
N
Y
Y
L
Q
S
A
K
V
L
E
D
P
K
L
A
E
Q
L
A
L
E
L
A
K
Q
I
Q
E
A
--
H
-
L
N
I
E
C
V
C
S
P
A
I
G
G
I
L
A
G
Y
E
L
A
R
A
L
------
G
V
---------
R
F
I
F
T
E
R
--
V
---
D
---------------------
N
--------------
T
------------------
M
A
L
R
R
G
F
--------------
E
--
V
K
K
N
E
K
I
L
V
C
E
D
I
I
T
T
G
K
S
A
M
E
C
A
K
V
L
E
E
K
G
A
Q
I
V
-------------
A
F
G
A
L
A
---
N
R
GI
C
K
R
A
HSH
L
K
A
Q
E
--
G
---------------
A
-------
C
-------
L
P
SH
L
------------
P
L
F
A
L
E
D
F
V
-
F
-
D
M
-
H
K
P
S
S
C
-
P
L
C
A
T
S
V
A
I
K
P
-----------
21
PsiBlast_CBE
85.04
47%
-116
- C4 -
4PAW
3
PYRE_HELPY
B:
[29-167]
----------------------------------------------------------------------------------
Y
Q
N
A
K
A
L
L
E
---
G
H
F
L
L
S
----
S
G
F
H
S
N
Y
Y
L
Q
S
A
K
V
L
E
D
P
K
L
A
E
Q
L
A
L
E
L
A
K
Q
I
Q
-
E
A
-
H
-
L
N
I
E
C
V
C
S
P
A
I
G
G
I
L
A
G
Y
E
L
A
R
A
L
------
G
V
---------
R
F
I
F
T
E
R
--
V
---
D
---------------------
N
--------------
T
------------------
M
A
L
R
R
G
F
--------------
E
--
V
K
K
N
E
K
I
L
V
C
E
D
I
I
T
T
G
K
S
A
M
E
C
A
K
V
L
E
E
K
G
A
Q
I
V
-------------
A
F
G
A
L
A
---
N
R
------------
G
I
--
C
---------------
K
-------
R
-------
A
H
--
S
------------
H
L
K
A
Q
E
G
A
C
-
L
-
P
S
-
H
L
P
L
F
A
L
E
D
F
V
F
D
M
H
K
P
S
S
C
P
L
C
A
T
S
V
A
I
1
PsiBlast_PDB
83.40
47%
-115
- C4 -
4PAW
3
PYRE_HELPY
A:
[29-167]
----------------------------------------------------------------------------------
Y
Q
N
A
K
A
L
L
E
---
G
H
F
L
L
S
----
S
G
F
H
S
N
Y
Y
L
Q
S
A
K
V
L
E
D
P
K
L
A
E
Q
L
A
L
E
L
A
K
Q
I
Q
-
E
A
-
H
-
L
N
I
E
C
V
C
S
P
A
I
G
G
I
L
A
G
Y
E
L
A
R
A
L
------
G
V
---------
R
F
I
F
T
E
R
--
V
---
D
---------------------
N
--------------
T
------------------
M
A
L
R
R
G
F
--------------
E
--
V
K
K
N
E
K
I
L
V
C
E
D
I
I
T
T
G
K
S
A
M
E
C
A
K
V
L
E
E
K
G
A
Q
I
V
-------------
A
F
G
A
L
A
---
N
R
------------
G
I
--
C
---------------
K
-------
R
-------
A
H
--
S
------------
H
L
K
A
Q
E
G
A
C
-
L
-
P
S
-
H
L
P
L
F
A
L
E
D
F
V
F
D
M
H
K
P
S
S
C
P
L
C
A
T
S
V
A
I
46
HHSearch
74.11
24%
-76
- C4 -
2PS1
4
PYRE_YEAST
A:
[4-204]
----------------------------------------------------------------------
M
L
E
D
Y
Q
K
N
F
L
E
L
A
I
E
C
Q
A
L
R
F
---
G
S
F
K
L
K
----
S
G
R
E
S
P
Y
F
F
N
L
G
L
-
F
N
T
G
K
L
L
S
N
L
A
T
A
Y
A
I
A
I
I
Q
S
--
D
-
L
K
F
D
V
I
F
G
P
A
Y
K
G
I
P
L
A
A
I
V
C
V
K
L
------
A
E
IGGSKFQN
I
Q
Y
A
F
N
R
K
EA
K
D--
H
---------------------
G
--------------
E
------------------
G
G
I
I
V
G
S
-----------------
A
L
E
N
K
R
I
L
I
I
D
D
V
M
T
A
G
T
A
I
N
E
A
F
E
I
I
S
N
A
K
G
Q
V
V
-------------
G
S
I
I
A
L
---
D
R
------------
Q
E
--
V
VSTDDKEGLS
A
T
Q
T
V
S
-------
K
K
------
Y
G
--
I
------------
P
V
L
S
I
V
S
L
I
H
I
-
I
T
-
Y
L
E
G
R
I
T
A
E
E
K
S
K
I
E
Q
Y
L
Q
T
Y
G
A
S
A
----
49
HHSearch
72.85
21%
-85
- C4 -
2AEE
4
PYRE_STRP1
A:
[3-184]
------------------------------------------------------------------------
M
T
L
A
S
Q
I
A
T
Q
L
L
D
I
K
A
V
Y
L
KPE
D
P
F
T
W
A
----
S
G
I
K
S
P
I
Y
T
D
N
R
V
T
L
S
Y
P
K
T
R
D
L
I
E
N
G
F
V
E
T
I
K
A
H
--
F
-
P
E
V
E
V
I
A
G
T
A
T
A
G
I
P
H
G
A
I
I
A
D
K
M
------
T
L
---------
P
F
A
Y
I
R
S
--
K
PK---------------------------------------------------------
G
N
Q
I
E
G
---------------
R
--
V
L
K
G
Q
K
M
V
I
I
E
D
L
I
S
T
G
G
S
V
L
D
A
A
A
A
A
S
R
E
G
A
D
V
L
-------------
G
V
V
A
I
F
---
T
Y
------------
E
L
--
P
K
A
S
Q
N
----------
F
-------
K
E
------
A
G
--
I
------------
K
L
I
T
L
S
N
Y
T
E
L
-
I
A
-
V
A
K
L
Q
G
Y
I
T
N
D
G
L
H
L
L
K
K
F
K
E
D
Q
V
N
W
Q
--
54
HHSearch
72.14
19%
-82
- C4 -
1QB7
3
?
A:
[21-234]
----------------------------------------------------------------------------------------
L
L
K
---
K
S
Y
R
W
Y
S
PVF
S
P
R
N
V
P
R
F
A
D
V
S
S
I
T
E
S
P
E
T
L
K
A
I
R
D
F
L
V
Q
R
Y
R
A
M
--
S
-
P
A
P
T
H
I
L
G
F
D
A
R
G
F
L
F
G
P
M
I
A
V
E
L
------
E
I
---------
P
F
V
L
M
R
K
--
A
DKN
A
---------------------
G
--------------
L
L
I
R
S
E
P
Y
E
KEYKEAAPEV
M
T
I
R
Y
G
---------------
S
--
I
G
K
G
S
R
V
V
L
I
D
D
V
L
A
T
G
G
T
A
L
S
G
L
Q
L
V
E
A
S
D
A
V
V
V
-------------
E
M
V
S
I
L
---
S
I
------------
P
F
LK
A
A
E
K
------------
I
-------
H
S
TANSRY
K
D
--
I
------------
K
F
I
S
L
L
S
D
D
----
A
-
L
T
E
E
N
C
G
D
S
K
N
Y
T
G
P
R
V
L
S
C
G
D
V
L
A
E
H
P
H
61
HHSearch
71.92
23%
-112
- C4 -
1O57
5
PURR_BACSU
A:
[101-254]
--------------------------------------------------------------------------------------------------------------
G
Y
V
Y
L
T
D
I
L
G
K
P
S
V
L
S
K
V
G
K
L
F
A
S
V
F
A
E
-----
R
E
I
D
V
V
M
T
V
A
T
K
G
I
P
L
A
Y
A
A
A
S
Y
L
------
N
V
---------
P
V
V
I
V
R
K
D---------------------------
G
--------------
S
T
V
S
I
N
Y
V
S
GSSN
R
I
Q
T
--
M
S
L
A
K
R
---------------
S
--
M
K
T
G
S
N
V
L
I
I
D
D
F
M
K
A
G
G
T
I
N
G
M
I
N
L
L
D
E
F
N
A
N
V
A
-------------
G
I
G
V
L
V
---
E
A
------------
E
G
--
V
---------------
D
E------
R
-------
L
V
--
D
------------
E
Y
M
S
L
L
T
L
S
-
T
-
I
N
-
M
K
E
K
S
I
E
I
Q
N
G
N
F
L
R
F
F
K
D
N
---------
67
Fugue
70.25
17%
-78
- C4 -
1QB7
3
?
A:
[1-236]
-------------------------------------------------------------PFKEVSPN
S
F
L
L
D
D
S
H
A
L
S
Q
L
L
K
K
S
Y
R
W
Y
S
---
P
V
F
S
P
R
----
N
V
P
---
R
F
A
D
V
S
S
I
T
E
S
P
E
T
L
K
A
I
R
D
F
L
V
Q
R
Y
R
A
-
M
-
S
-
P
A
P
T
H
I
L
G
F
D
A
R
G
F
L
F
G
P
M
I
A
V
E
L
------
E
I
---------
P
F
V
L
M
R
K
--
A
---
D
KNA
G
L
L
I
R
S
E
P
Y
E
KEYKEAAP
E
--------------
V
------------------
M
T
I
R
Y
G
---------------
S
--
I
G
K
G
S
R
V
V
L
I
D
D
V
L
A
T
G
G
T
A
L
S
G
L
Q
L
V
E
A
S
D
A
V
V
V
-------------
E
M
V
S
I
L
SIP
F
L
------------
K
A
--
A
---------------
E
-------
K
-------
I
H
--
S
TANSRYKD
I
K
F
I
S
L
L
S
D
D
A
L
T
-
E
-
E
N
-
C
G
D
S
K
N
Y
T
G
P
R
V
L
S
-----
C
G
D
V
L
A
E
H
P
H
56
HHSearch
69.86
19%
-116
* C4 *
1ZN8
1
APT_HUMAN
A:
[5-180]
------------------------------------------------------------------------------
E
L
Q
L
V
E
Q
R
-
I
R
S
F
---
P
D
F
P
T
P
-----
G
---
V
V
F
R
D
I
S
P
V
L
K
D
P
A
S
F
R
A
A
I
G
L
L
A
R
H
L
K
A
T
H
-
G
-
G
R
I
D
Y
I
A
G
L
D
S
R
G
F
L
F
G
P
S
L
A
Q
E
L
------
G
L
---------
G
C
V
L
I
R
K
RG
K
L--
P
---------------------
G
P
T
L
W
A
S
Y
S
L
EY
G
K
A
E
------------------
L
E
I
Q
K
D
A
-----------------
L
E
P
G
Q
R
V
V
V
V
D
D
L
L
A
T
G
G
T
M
N
A
A
C
E
L
L
G
R
L
Q
A
E
V
L
-------------
E
C
V
S
L
V
---
E
L
------------
T
S
--
L
K
G
-------------
R
-------
E
K
L
-----
A
P
--
V
------------
P
F
F
S
L
L
Q
Y
E
-----------------------------------
2
PsiBlast_PDB
69.25
25%
-102
- C4 -
2WNS
2
UMPS_HUMAN
A:
[4-150]
----------------------------------------------------------------------------
G
P
L
V
T
G
L
Y
D
V
Q
A
F
K
F
---
G
D
F
V
L
K
----
S
G
L
S
S
P
I
Y
I
D
L
R
G
I
V
S
R
P
R
L
L
S
Q
V
A
D
I
L
F
-
Q
T
A
Q
N
A
-
G
-
I
S
F
D
T
V
C
G
V
P
Y
T
A
L
P
L
A
T
V
I
C
S
T
N
------
Q
I
---------
P
M
L
I
R
R
K
--
E
---
T
---------------------
K
--------------
D
------------------
Y
G
T
K
R
L
V
--------------
E
GT
I
N
P
G
E
T
C
L
I
I
E
D
V
V
T
S
G
S
S
V
L
E
T
V
E
V
L
Q
K
E
G
L
K
V
T
-------------
D
A
I
V
L
L
---
D
R
------------
E
Q
--
G
---------------
G
-------
K
-------
D
K
--
L
------------
Q
A
H
G
I
R
L
H
S
-
V
-
C
T
-
L
S
K
M
L
E
I
L
E
Q
Q
K
K
V
D
A
E
T
V
G
R
V
K
R
F
I
Q
E
-
44
HHSearch
68.86
24%
-79
- C4 -
2WNS
2
UMPS_HUMAN
A:
[2-190]
--------------------------------------------------------------------------
A
L
G
P
L
V
T
G
L
Y
D
V
Q
A
F
K
F
---
G
D
F
V
L
K
----
S
G
L
S
S
P
I
Y
I
D
L
R
G
I
V
S
R
P
R
L
L
S
Q
V
A
D
I
L
F
Q
T
A
Q
N
A
--
G
-
I
S
F
D
T
V
C
G
V
P
Y
T
A
L
P
L
A
T
V
I
C
S
T
N
------
Q
I
---------
P
M
L
I
R
R
K
ET
K
D--
Y
---------------------
G
--------------
T
------------------
K
R
L
V
E
G
T
-----------------
I
N
P
G
E
T
C
L
I
I
E
D
V
V
T
S
G
S
S
V
L
E
T
V
E
V
L
Q
K
E
G
L
K
V
T
-------------
D
A
I
V
L
L
---
D
R
------------
E
Q
--
G
G
K
D
K
-----------
L
-------
Q
A
------
H
G
--
I
------------
R
L
H
S
V
C
T
L
S
K
M
-
L
E
-
I
L
E
Q
Q
K
K
V
D
A
E
T
V
G
R
V
K
R
F
I
Q
E
-------
52
HHSearch
68.67
21%
-86
- C4 -
3N2L
1
PYRE_VIBCH
A:
[26-219]
-----------------------------------------------------------------------
M
K
A
Y
Q
R
E
F
I
E
F
A
L
E
K
Q
V
L
K
F
---
G
E
F
T
L
K
----
S
G
R
K
S
P
Y
F
F
N
A
G
L
-
F
N
T
G
R
D
L
A
R
L
G
R
F
Y
A
A
A
L
V
D
S
--
G
-
I
E
F
D
V
L
F
G
P
A
Y
K
G
I
P
I
A
T
T
T
A
V
A
L
A
D
HHD
V
D
T
---------
P
Y
C
F
N
R
K
--
E
-------------------------------------------------------------
N
L
V
G
------------------
S
K
L
E
G
R
V
M
L
V
D
D
V
I
T
A
G
T
A
I
R
E
S
M
E
L
I
Q
A
N
K
A
D
L
A
-------------
G
V
L
V
A
I
---
D
R
------------
Q
E
--
K
GKGE-----------
L
S
A
I
Q
E
V
E
R
D
------
F
G
--
C
------------
A
V
I
S
I
V
S
L
T
D
L
-
I
T
-
Y
L
E
Q
Q
G
N
N
T
E
H
L
E
A
V
K
A
Y
R
A
Q
Y
G
I
-----
70
Fugue
67.88
17%
-78
- C4 -
1O57
6
PURR_BACSU
A:
[2-276]
KFR
R
S
G
R
L
V
D
L
T
N
Y
L
L
T
H
PH
E
L
I
P
L
T
F
F
S
E
R
Y
ESA
K
S
S
I
S
E
D
L
T
I
I
K
Q
T
F
E
Q
Q
GI
G
T
L
L
T
V
P
G
AA
G
G
V
K
Y
I
P
K
M
K
Q
A
E
A
E
E
F
V
Q
T
L
G
Q
S
L
A
---
N
P
E
R
I
L
----
P
G
G
Y
V
Y
L
----
T
D
I
L
G
K
P
S
V
L
S
K
V
G
K
L
F
A
S
V
F
A
----
E
-
R
E
I
D
V
V
M
T
V
A
T
K
G
I
P
L
A
Y
A
A
A
S
Y
L
------
N
V
---------
P
V
V
I
V
R
K
--
D
---
G
---------------------
S
--------------
T
------------------
V
S
I
N
Y
V
S
GSSN
R
I
Q
T
M
S
L
A
KR
S
--
M
K
T
G
S
N
V
L
I
I
D
D
F
M
K
A
G
G
T
I
N
G
M
I
N
L
L
D
E
F
N
A
N
V
A
-------------
G
I
G
V
L
V
---
E
A
E-----------
G
V
--
D
---------------
E
-------
R
-------
L
V
--
D
------------
E
Y
M
S
L
L
T
L
S
----------
T
I
N
M
K
E
K
S
I
E
I
Q
N
G
N
F
L
R
F
F
K
D
N
--
68
Fugue
67.88
19%
-61
- C4 -
4OHC
5
?
A:
[10-230]
----------------------------------------------------------------TGYD
R
Q
S
I
S
D
T
T
A
K
I
L
L
E
V
Q
A
V
H
F
N
A
E
---
K
P
F
I
F
T
----
S
G
W
A
S
P
V
Y
I
D
C
R
K
L
I
S
Y
P
R
V
R
R
A
L
M
E
M
A
E
T
T
I
T
R
D
I
-
G
F
E
Q
I
D
A
V
A
G
G
E
T
A
G
I
P
F
A
A
W
I
A
D
R
M
------
M
V
---------
P
M
Q
Y
V
R
K
--
K
---
P
---------------------
K
--------------
G
------------------
F
G
R
N
A
Q
I
--------------
E
GH
L
E
E
G
S
R
V
L
L
V
E
D
L
T
T
D
S
R
S
K
I
N
F
V
N
A
L
R
T
A
G
A
T
V
N
H
C
F
V
LFHYNIFKE
S
V
S
V
L
K
---
D
I
------------
D
V
--
D
---------------
L
-------
H
-------
A
L
--
A
------------
T
W
W
D
V
L
R
V
A
-
K
-
A
S
G
Y
F
E
T
K
T
L
D
E
V
E
K
F
L
H
---
A
P
A
E
W
S
A
A
H
G
G
3
PsiBlast_PDB
67.75
20%
-102
- C4 -
3QW4
-
?
B:
[262-409]
------------------------------------------------------------------------------
L
A
K
A
L
V
D
S
H
C
V
R
F
---
G
N
F
T
L
K
----
S
G
K
S
S
P
I
Y
I
D
L
R
R
L
V
T
Y
P
A
----
I
M
R
L
V
A
R
E
Y
A
K
V
L
R
H
-
Y
K
F
D
R
I
A
G
L
P
Y
A
A
L
P
I
A
S
A
I
S
N
E
M
------
N
V
---------
P
L
I
Y
P
R
R
--
E
---------------------------------------------------------------
A
A
I
--------------
E
GE
Y
K
K
G
D
R
V
V
I
I
D
D
L
V
S
T
-
E
T
K
V
E
A
I
E
K
L
R
S
A
G
L
E
V
V
-------------
S
I
V
V
L
V
---
D
R
------------
D
M
--
G
---------------
A
-------
K
-------
A
F
--
L
------------
N
K
L
G
Y
D
F
E
A
-
V
-
V
G
-
L
H
Q
L
L
P
L
W
R
K
S
N
A
I
T
S
Q
Q
E
A
D
V
R
A
F
L
G
Q
W
45
HHSearch
67.43
22%
-78
- C4 -
2YZK
-
PYRE_AERPE
A:
[1-176]
-----------------------------------------------------------------------------
M
L
A
K
V
L
K
K
R
G
A
V
L
R
---
G
D
F
V
L
S
----
S
G
R
R
S
S
V
Y
I
D
M
R
R
L
L
G
D
E
S
S
Y
S
V
A
L
D
L
L
L
E
V
G
G
Q
D
--
L
-
A
R
S
S
A
V
I
G
V
A
T
G
G
L
P
W
A
A
M
L
A
L
R
L
------
S
K
---------
P
L
G
Y
V
R
P
E
R
K
G--
H
---------------------
G
--------------
T
------------------
L
S
Q
V
E
G
------------------
D
P
P
K
G
R
V
V
V
V
D
D
V
A
T
T
G
T
S
I
A
K
S
I
E
V
L
R
S
N
G
Y
T
V
G
-------------
T
A
L
V
L
V
---
D
R
------------
G
E
--
G
A
G
E
L
-----------
L
-------
A
R
------
M
G
--
V
------------
R
L
V
S
V
A
T
L
K
T
I
-
L
E
-
K
L
G
W
G
G
-----------------------
58
HHSearch
66.90
21%
-98
- C4 -
2DY0
-
APT_ECOLI
A:
[24-181]
-----------------------------------------------------------------------------------------------------------
P
G
I
L
F
R
D
V
T
S
L
L
E
D
P
K
A
Y
A
L
S
I
D
L
L
V
E
R
Y
K
N
-----
A
G
I
T
K
V
V
G
T
E
A
R
G
F
L
F
G
A
P
V
A
L
G
L
------
G
V
---------
G
F
V
P
V
R
K
P
G
K
---
L
P
R
E
T
I
S
E
T
Y
D
L
EY--------
G
T
D
------------
Q
------------------
L
E
I
H
V
D
---------------
A
--
I
K
P
G
D
K
V
L
V
V
D
D
L
L
A
T
G
G
T
I
E
A
T
V
K
L
I
R
R
L
G
G
E
V
A
-------------
D
A
A
F
I
I
---
N
L
------------
F
D
LG
G
E
Q
R
------------
L
-------
E
K
------
Q
G
--
I
------------
T
S
Y
S
L
V
P
F
P
-
G
-
H
-------------------------------
48
HHSearch
66.24
20%
-68
- C4 -
3DEZ
3
PYRE_STRMU
A:
[36-227]
-------------------------------------------------------------------------
T
L
A
K
D
I
A
R
D
L
L
D
I
K
A
V
Y
L
K
PE
E
P
F
T
W
-------
I
K
S
P
I
Y
T
D
N
R
I
T
L
S
Y
P
E
T
R
T
L
I
E
N
G
F
V
E
T
I
K
E
A
--
F
-
P
E
V
E
V
I
A
G
T
A
T
A
G
I
P
H
G
A
I
I
A
D
K
M
------
N
L
---------
P
L
A
Y
I
R
S
KP
K
------------------------------------------------------------
N
Q
I
E
G
---------------
R
--
V
T
K
G
Q
K
M
V
I
I
E
D
L
I
S
T
G
G
S
V
L
D
A
V
A
A
A
Q
R
E
G
A
D
V
L
-------------
G
V
V
A
I
F
---
T
Y
------------
E
L
--
P
K
A
T
A
N
----------
F
-------
E
K
------
A
S
--
V
------------
K
L
V
T
L
S
N
Y
S
-
E
L
I
K
-
V
A
K
V
Q
G
Y
I
D
A
D
G
L
T
L
L
K
K
F
K
E
N
Q
E
T
W
Q
D
-
7
PsiBlast_PDB
66.04
22%
-93
- C4 -
4RV4
3
PYRE_BACAN
A:
[47-199]
------------------------------------------------------------------------------------------------
F
T
W
S
----
S
G
M
K
S
P
I
Y
C
D
N
R
L
T
L
S
Y
P
K
V
R
Q
T
I
A
A
G
L
E
E
L
I
K
E
H
F
---
P
T
V
E
V
I
A
G
T
A
T
A
G
I
A
H
A
A
W
V
S
D
R
M
------
D
L
---------
P
M
C
Y
V
R
-----------------------------------------------------------------
Q
I
E
G
---------------
K
--
A
E
K
G
Q
K
V
V
V
V
E
D
L
I
S
T
G
G
S
A
I
T
C
V
E
A
L
R
E
A
G
C
E
V
L
-------------
G
I
V
S
I
F
---
T
Y
------------
E
L
--
E
---------------
A
G
------
K
-------
E
K
--
L
------------
E
A
A
N
V
A
S
Y
S
-
L
-
S
D
-
Y
S
A
L
T
E
V
A
A
E
K
G
I
I
G
Q
A
E
T
K
K
L
Q
E
W
R
K
N
P
59
HHSearch
65.89
17%
-99
- C4 -
1G2Q
-
APT1_YEAST
A:
[6-178]
--------------------------------------------------------------------------
Y
A
Q
E
L
K
L
A
L
H
Q
Y
P
N
F
P
S
---
E
G
-------------
I
L
F
E
D
F
L
P
I
F
R
N
P
G
L
F
Q
K
L
I
D
A
F
K
L
H
L
E
E
A
F
P
E
-
V
K
I
D
Y
I
V
G
L
E
S
R
G
F
L
F
G
P
T
L
A
L
A
L
------
G
V
---------
G
F
V
P
V
R
K
--
A
GKL
P
---------------------
G
--------------
E
C
F
K
A
T
Y
E
K
EY
G
S
D
L
----
F
E
I
Q
K
N
---------------
A
--
I
P
A
G
S
N
V
I
I
V
D
D
I
I
A
T
G
G
S
A
A
A
A
G
E
L
V
E
Q
L
E
A
N
L
L
-------------
E
Y
N
F
V
M
---
E
L
------------
D
F
LK
G
---------------
R
-------
S
K------
L
N
--
A
------------
P
V
F
T
L
L
--------------------------------------