@TOME V2.3
(Nov 2016)
Ref.
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SA0194: (2016-03-13 )
MLKLHKKIAWTGIKGSAITTFITALYNGSSVWNALAVAGIAFGGGAGTAVAALGRATVMRFIKRWGVRKTAAW
Atome Classification :
(16 SA)
---------------------------------......-.-..10-....-....20........30..---.-......40...-......50....----....60----........70..----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---------------------------------MLKLHK-K-IAWT-GIKG-SAITTFITALYNGSS-VW---N-ALAVAGI-AFG-GGAGTAVAALGR----ATVMRF----IKRWGVRKTAAW----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
Fugue
85.36
26%
-114
- C4 -
4M59
3
?
A:
[6-714]
PD
A
Q
V
L
V
L
A
I
S
S
HPLPT
L
A
A
F
L
A
S
R
R
D
E
L
L
R
AD
I
T
S
L
L
K
-
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G
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E
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---
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----
E
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L
P
P
----
G
S
R
L
D
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R
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T
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L
H
A
L
S
R
A
GR
Y
E
R
A
L
E
L
F
A
E
L
R
R
Q
G
V
A
P
T
L
V
T
Y
N
V
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D
V
Y
G
R
M
GRS
W
P
R
I
V
A
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V
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G
F
T
A
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T
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I
A
A
C
S
R
D
GL
V
D
E
A
V
A
F
F
E
D
L
K
A
R
GHAPS
V
V
T
Y
N
A
L
L
Q
V
F
G
KAGN
Y
T
E
A
L
R
V
L
G
E
M
E
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N
G
C
Q
P
D
A
V
T
Y
N
E
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A
G
TE
E
A
A
R
C
L
D
T
M
A
SPN
A
F
T
Y
N
T
V
M
T
A
Y
G
N
V
GKV
D
E
A
L
A
L
F
D
Q
M
KKT
G
F
V
P
N
V
N
T
Y
N
L
V
L
G
M
L
G
K
K
SR
F
T
V
M
L
E
M
L
G
E
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S
R
S
G
C
T
P
N
R
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N
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M
L
AVSGKRG
M
E
D
Y
V
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G
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E
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S
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T
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T
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A
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GS
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M
Y
N
E
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C
I
T
T
Y
N
A
L
L
N
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GD
W
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A
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GN
V
A
G
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A
A
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E
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GSGAVFPS
W
V
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I
A
N
F
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C
RR
L
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M
E
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A
F
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K
A
RG
Y
N
P
D
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M
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Y
A
K
N
GM
Y
S
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D
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M
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A
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C
SE
S
W
E
A
E
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K
C
SQTMKPD
V
V
S
Y
N
T
V
I
N
G
F
C
K
QGL
V
K
E
A
Q
R
V
L
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M
V
A
D
G
M
A
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C
A
V
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T
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V
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G
Y
S
S
LEMF
S
E
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M
V
QHGLKPMEL
T
Y
R
R
V
V
E
S
Y
C
R
AF
E
E
A
R
G
F
L
S
EVKAL
E
A
Y
I
E
D
A
12
Fugue
83.29
31%
-150
- C4 -
1E68
-
?
A:
[1-70]
---------------------------------
M
A
K
E
F
---------
G
I
P
A
-
A
V
A
G
T
V
L
N
V
V
E
A
G
G
W
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V
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---
T
-
I
V
S
I
L
T
--
A
V
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S
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L
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R
ES
I
K
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L
K
K
E
----
I
K
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K
G
K
R
A
V
I
A
W
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
Fugue
71.98
15%
-122
- C4 -
4G3A
-
CLASP_DROME
A:
[5-231]
-----------------------------KPSD
L
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V
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S
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VCT
D
M
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M
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W
L
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T
G
S
H
F
K
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A
Q
K
S
L
----
E
A
F
S
E
L
----
I
K
R
L
G
S
D
F
N
A
Y
T
ATV
L
P
H
V
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R
L
G
DSR
D
T
V
R
E
K
A
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L
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M
E
H
RVLP
P
Q
A
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A
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S
C
F
KHKN
A
K
V
R
E
E
F
L
Q
T
I
V
N
A
L
H
E
YGTQQLSVRVY
I
P
P
V
C
A
L
LGDPT
V
N
V
R
E
A
A
I
Q
T
L
V
E
I
Y
K
H
VGD
R
L
R
P
D
L
R
R
MDDVP
A
S
K
L
A
M
L
E
Q
K
F
D
Q
V
K
L
E-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
Fugue
49.48
14%
-79
- C4 -
4WLP
-
NFRKB_HUMAN
B:
[1-114]
---EDLLED
P
E
I
F
F
D
V
V
S
L
S
T
W
Q
E
V
LSDSQ
R
E
H
L
Q
Q
F
L
P
-
Q
---
F
P
-
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D
S
A
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E
Q
Q
N
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L
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FG-
N
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R
----
Q
L
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F
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----
Q
Y
K
R
Y
L
N
S
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Q
Q
Y
F
H
R
L
L
K
Q
I
L
A
S-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
Fugue
46.40
13%
-32
- C4 -
3C4R
-
?
A:
[2-125]
-------------------------------KI
K
H
E
H
I
R
M
A
M
N
A
W
A
-
H
P
D
G
E
K
V
P
A
A
E
I
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R
A
Y
F
E
L
G
M
T
F
---
P
-
E
L
--------
Y
-
D
D
S
H
P
E
A
L
A
R
N
T
----
Q
K
I
F
R
W
----
V
E
K
D
T
P
D
A
V
E
K
I
Q
A
L
L
P
A
I
E
K
SMP
P
L
L
V
A
R
M
R
SHSS
A
Y
F
R
E
L
V
E
T
R
E
R
L
V
R
D
A
D
D
F
V
A
V
A
I
A
G
F------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
Fugue
34.30
40%
-2
* C4 *
4B1V
1
PHAR1_MOUSE
M:
[5-30]
---------------------------------------------------------------------------------------------
S
A
A
L
E
R
----
K
I
S
M
R
Q
SREE
L
I
K
R
G
V
L
K
E
I
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
Fugue
29.02
20%
-44
- C4 -
1ZRW
-
SPING_PSEUS
A:
[1-25]
-----------------------------------------------------------------------------------
H
V
D
-
K
K
V
A
D
K
V
L
L
L
K
Q
----
L
R
I
M
R
L
----
L
T
R
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
25.65
24%
-65
- C4 -
1JKO
2
C:
[33-46]
------------------------------------------------------------------------------------------------
I
G
V
----
S
T
L
Y
R
Y
----
F
P
A
S
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
24.12
36%
158
- C2 -
3X2D
-
VGP_MABVR
A:
[50-60]
------------------------------------------------------------------------------------------------------------
A
----
S
K
R
W
A
F
R
T
G
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
HHSearch
23.75
42%
146
- C1 -
3S88
-
VGP_EBOSU
I:
[66-108]
-----------------------------------------------------------------------------------------------------------
S
A
----
T
K
R
W
G
F
R
S
G
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
HHSearch
22.47
14%
-4
- C4 -
1Q90
3
M:
[4-25]
-----------------------------------------------------------
E
F
I
A
G
T
A
L
-
T
M
---
V
-
G
M
T
L
V
G
L
-
A
I
G
-
F
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
22.14
42%
158
- C3 -
3CSY
-
VGP_EBOZM
I:
[66-121]
-----------------------------------------------------------------------------------------------------------
S
A
----
T
K
R
W
G
F
R
S
G
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
HHSearch
19.01
32%
9
- C4 -
1AFO
-
GLPA_HUMAN
A:
[72-90]
-----------------------------------------------------------------------------
E
I
T
L
I
-
I
F
G
-
V
M
A
G
V
I
G
T
I
L
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
18.18
32%
49
- C4 -
3B9W
-
?
A:
[28-46]
-----------------------------------------------------------------------------------------------
L
V
G
F
----
G
F
L
M
V
F
----
V
R
R
Y
G
F
S
A
T
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
HHSearch
17.20
25%
40
- C4 -
3HD6
-
RHCG_HUMAN
A:
[75-116]
----------------------------------------------------------------------------------------------
V
F
V
G
F
----
G
F
L
M
T
F
----
L
Q
R
Y
G
F
S
A
V
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
13.33
33%
52
- C4 -
2K9Y
-
EPHA2_HUMAN
A:
[536-550]
-----------------------------------------------------------------------------
A
V
I
G
G
-
V
A
V
-
G
V
V
L
L
L
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------