@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SA1197: (2016-03-23 )
MTTVLFVGLGLIGGSLASNIKYHNPNTNIIAYDADTSQLDKAKSIGIINEKCLNYSEAIKKADVIIYATPVAITNKYLSELIDMPTKPGVIVSDTGSTKAMIQQHESNLLKHNIHLVSGHPMAGSHKSGVLNAKKHLFENAYYILVYNEPRNEQAANTLKELLSPTLAKFIVTTAEEHDYVTSVVSHLPHIVASSLVHVSQKNGQEHHLVNKLAAGGFRDITRIASSNAQMWKDITLSNKTYILEMIRQLKSQFQDLERLIESNDSEKLLSFFAQAKSYRDALPAKQLGGLNTAYDLYVDIPDESGMISKVTYIMSLHNISISNLRILEVREDIYGALKISFKNPTDRERGMQALSDFDCYIQ
Atome Classification :
(20 SA)
---------.........10........20.....----.----..30......--..40...-----------....------------.50------------......-..60.........--70.-..-..--.-..---.80--.-----....-....90...-----....-..-100...-....110--........120..-.....-.130........140.....-..150.-------....--------...160.......170-.......--.180........190..---.....200-........210.......220---....---.---...230....-...240.......250.......260.......270.......280--------------------------------........290.......300.......310.......320.......330.......340.......350.......360.
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---------M
T
T
V
L
F
V
G
L
G
LI
G
G
S
L
ASN
I
K
YHNPN----T----
N
I
I
A
YDAD
T
S
--
Q
L
DKAKS-----------IG
I
I
------------
N
E
K
------------CL
N
Y
S
E
-
A
IK-KA
D
V
I
I
Y
AT--
P
-
V
-
A
I
-
T
N
--
K
-
Y
L
---
S
E
---
L
-----IDMP-TKP
G
V
-
I
V
S-----DTG
S
-
T
K
-
A
M
I
Q
Q
H
-
E
S
N
L
L
K
---H
N
I
H
L
VSGHP-MA-GSHKS-G
V
L
-
N
A
K
K
H
L
FEN
A
Y
Y
I
L
V
Y-NEP-R
N
-------
E
Q
A
A
--------
N
T
L
K
E
L
L
S
P
T
L
A
K
F
-
I
-
V
TTAEE
H
--
D
Y
V
-
T
S
V
V
S
H
L
P
H
I
V
A
S
---
S
L
V
H
V
SQ--KNG
Q
E
H
H
L
V
N
K
L
AAG
G
F
R
D
I
----
T
R
I
A
---S---SNA
Q
M
W
K
D
IT-LS
N
K
T
Y
I
L
E
M
I
R
Q
L
K
S
Q
F
Q
D
L
E
R
L
I
ESN
D
S
E
K
L
L
S
F
F
A
Q
A
K
S
Y
R
D---------------------------------AL
P
A
K
QLGGLNT
A
Y
D
L
Y
V
DIPDESG
M
I
S
K
V
T
Y
I
M
S
L
HNISIS
N
L
R
I
L
E
V
R
E
DI
Y
G
A
L
K
I
S
FKNP
T
D
R
E
R
G
M
Q
A
L
SDFDCYIQ
23
HHSearch
91.15
39%
-87
- C2 -
3B1F
1
?
A:
[6-289]
---------
E
K
T
I
Y
I
A
G
L
G
L
I
G
A
S
L
A
L
G
I
K
R
D
H
P
H
----
Y
----
K
I
V
G
Y
N
R
S
D
R
--
S
R
D
I
A
L
E
-----------
R
G
I
V
------------
D
E
A
------------
T
A
D
F
K
V
-
F
A
A
-
L
A
D
V
I
I
L
A
V
--
P
-
I
-
K
K
-
T
I
--
D
-
F
I
---
K
I
---
L
-----
A
D
-
L
D
L
K
E
D
V
-
I
I
T
-----
D
A
G
S
-
T
K
-
Y
E
I
V
R
A
-
A
E
Y
Y
L
K
D--
K
P
V
Q
F
V
G
S
H
P
-
M
A
-----
S
-
G
A
V
-
A
A
N
V
N
L
F
E
N
A
Y
Y
I
F
S
P
-
S
C
L
T
K
P
--------
N
T
I
--------
P
A
L
Q
D
L
L
S
G
L
H
A
R
Y
-
V
-
E
I
D
A
A
E
H
--
D
C
V
-
T
S
Q
I
S
H
F
P
H
I
I
A
S
---
S
L
M
K
Q
A
G
--
D
F
S
E
S
H
E
M
T
K
H
F
A
A
G
G
F
R
D
M
----
T
R
I
A
---
E
---
S
E
P
G
M
W
T
S
I
L
-
L
T
N
Q
E
A
V
L
D
R
I
E
N
F
K
Q
R
L
D
E
V
S
N
L
I
K
A
R
D
E
N
A
I
W
A
F
F
N
Q
S
R
Q
I
R
K
---------------------------------
N
M
--------------------------------------------------------------------------------
2
PsiBlast_PDB
90.97
38%
-90
- C2 -
3B1F
1
?
A:
[8-286]
-----------
T
I
Y
I
A
G
L
G
L
I
G
A
S
L
A
L
G
I
K
R
D
H
P
H
----
Y
----
K
I
V
G
Y
N
R
S
D
R
--
S
R
D
I
A
L
E
-----------
R
G
I
V
------------
D
E
A
------------
T
A
D
F
K
V
-
F
A
A
-
L
A
D
V
I
I
L
A
V
--
P
-
I
-
K
K
-
T
I
--
D
-
F
I
---
K
I
---
L
-----
A
D
L
D
-
L
K
E
D
V
-
I
I
T
-----
D
A
G
S
-
T
K
Y
E
I
V
R
A
A
-
E
Y
Y
L
K
D
---
K
P
V
Q
F
V
G
S
H
P
-
M
A
-----
S
-
G
A
V
-
A
A
N
V
N
L
F
E
N
A
Y
Y
I
F
S
P
-
S
C
L
-
T
K
-------
P
N
T
I
--------
P
A
L
Q
D
L
L
S
G
L
H
A
R
Y
-
V
-
E
I
D
A
A
E
H
--
D
C
V
-
T
S
Q
I
S
H
F
P
H
I
I
A
S
---
S
L
M
K
Q
A
G
--
D
F
S
E
S
H
E
M
T
K
H
F
A
A
G
G
F
R
D
M
----
T
R
I
A
---
E
---
S
E
P
G
M
W
T
S
I
L
-
L
T
N
Q
E
A
V
L
D
R
I
E
N
F
K
Q
R
L
D
E
V
S
N
L
I
K
A
R
D
E
N
A
I
W
A
F
F
N
Q
S
R
Q
I
R
--------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
86.17
30%
-80
- C2 -
3GGG
2
?
D:
[33-310]
---------
M
Q
N
V
L
I
V
G
V
G
F
M
G
G
S
F
A
K
S
L
R
R
S
G
F
K
----
G
----
K
I
Y
G
Y
D
I
N
P
E
--
S
I
S
K
A
V
D
-----------
L
G
I
I
------------
D
E
G
------------
T
T
S
I
A
K
-
V
E
D
F
S
P
D
F
V
M
L
S
S
--
P
-
V
-
R
--
T
F
--
R
-
E
I
---
A
K
---
K
-----
L
S
Y
I
-
L
S
E
D
A
-
T
V
T
-----
D
Q
G
S
-
V
K
-
G
K
L
V
Y
D
-
L
E
N
I
L
G
---
K
--
R
F
V
G
G
H
P
-
I
A
-
G
T
E
K
S
-
G
V
E
-
Y
S
L
D
N
L
Y
E
G
K
K
V
I
L
T
P
-
T
K
K
-
T
D
-------
K
K
R
L
--------
K
L
V
K
R
V
W
E
D
V
G
G
V
V
-
E
-
Y
M
S
P
E
L
H
--
D
Y
V
-
F
G
V
V
S
H
L
P
H
A
V
A
F
---
A
L
V
D
T
L
I
--
H
M
S
T
P
E
V
D
L
F
K
Y
P
G
G
G
F
K
D
F
----
T
R
I
A
---
K
---
S
D
P
I
M
W
R
D
I
F
-
L
E
N
K
E
N
V
M
K
A
I
E
G
F
E
K
S
L
N
H
L
K
E
L
I
V
R
E
A
E
E
E
L
V
E
Y
L
K
E
V
K
I
K
R
--------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
84.81
30%
-78
- C2 -
3GGP
3
?
A:
[33-310]
---------
M
Q
N
V
L
I
V
G
V
G
F
M
G
G
S
F
A
K
S
L
R
R
S
G
F
K
----
G
----
K
I
Y
G
Y
D
I
N
P
E
--
S
I
S
K
A
V
D
-----------
L
G
I
I
------------
D
E
G
------------
T
T
S
I
A
K
-
V
E
D
F
S
P
D
F
V
M
L
S
S
--
P
-
V
-
R
--
T
F
--
R
-
E
I
---
A
K
---
K
-----
L
S
Y
I
-
L
S
E
D
A
-
T
V
T
-----
D
Q
G
S
-
V
K
-
G
K
L
V
Y
D
-
L
E
N
I
L
G
---
K
--
R
F
V
G
G
H
P
-
I
A
-
G
T
E
K
S
-
G
V
E
-
Y
S
L
D
N
L
Y
E
G
K
K
V
I
L
T
P
-
T
K
K
-
T
D
-------
K
K
R
L
--------
K
L
V
K
R
V
W
E
D
V
G
G
V
V
-
E
-
Y
M
S
P
E
L
H
--
D
Y
V
-
F
G
V
V
S
H
L
P
H
A
V
A
F
---
A
L
V
D
T
L
I
--
H
M
S
T
P
E
V
D
L
F
K
Y
P
G
G
G
F
K
D
F
----
T
R
I
A
---
K
---
S
D
P
I
M
W
R
D
I
F
-
L
E
N
K
E
N
V
M
K
A
I
E
G
F
E
K
S
L
N
H
L
K
E
L
I
V
R
E
A
E
E
E
L
V
E
Y
L
K
E
V
K
I
K
R
--------------------------------------------------------------------------------------------------------------------
21
HHSearch
84.67
31%
-81
- C2 -
2G5C
1
?
A:
[1-281]
---------
M
Q
N
V
L
I
V
G
V
G
F
M
G
G
S
F
A
K
S
L
R
R
S
--
G
----
F
K
G
--
K
I
Y
G
Y
D
I
N
P
E
--
S
I
S
K
A
V
D
-----------
L
G
I
I
------------
D
E
G
------------
T
T
S
I
A
K
V
E
D
F
-
S
P
D
F
V
M
L
S
S
--
P
-
V
-
R
T
-
F
R
--
E
-
I
A
---
K
K
---
L
-----
S
Y
-
I
-
L
S
E
D
A
-
T
V
T
-----
D
Q
G
S
-
V
K
-
G
K
L
V
Y
D
-
L
E
N
I
L
-----
G
K
R
F
V
G
G
H
P
-
I
A
-
G
T
E
K
S
-
G
V
E
-
Y
S
L
D
N
L
Y
E
G
K
K
V
I
L
T
P
-
T
K
K
T
D
K
--------
K
R
L
--------
K
L
V
K
R
V
W
E
D
V
G
G
V
V
-
E
-
Y
M
S
P
E
L
H
--
D
Y
V
-
F
G
V
V
S
H
L
P
H
A
V
A
F
---
A
L
V
D
T
L
I
--
H
M
S
T
P
E
V
D
L
F
K
Y
P
G
G
G
F
K
D
F
-------
A
---
K
---
S
D
P
I
M
W
R
D
I
F
-
L
E
N
K
E
N
V
M
K
A
I
E
G
F
E
K
S
L
N
H
L
K
E
L
I
V
R
E
A
E
E
E
L
V
E
Y
L
K
E
V
K
I
K
R
M
---------------------------------
E
I
--------------------------------------------------------------------------------
5
PsiBlast_PDB
83.37
30%
-77
- C2 -
3GGO
2
?
A:
[33-310]
---------
M
Q
N
V
L
I
V
G
V
G
F
M
G
G
S
F
A
K
S
L
R
R
S
G
F
K
----
G
----
K
I
Y
G
Y
D
I
N
P
E
--
S
I
S
K
A
V
D
-----------
L
G
I
I
------------
D
E
G
------------
T
T
S
I
A
K
-
V
E
D
F
S
P
D
F
V
M
L
S
S
--
P
-
V
-
R
--
T
F
--
R
-
E
I
---
A
K
---
K
-----
L
S
Y
I
-
L
S
E
D
A
-
T
V
T
-----
D
Q
G
S
-
V
K
-
G
K
L
V
Y
D
-
L
E
N
I
L
G
---
K
--
R
F
V
G
G
H
P
-
I
A
-
G
T
E
K
S
-
G
V
E
-
Y
S
L
D
N
L
Y
E
G
K
K
V
I
L
T
P
-
T
K
K
-
T
D
-------
K
K
R
L
--------
K
L
V
K
R
V
W
E
D
V
G
G
V
V
-
E
-
Y
M
S
P
E
L
H
--
D
Y
V
-
F
G
V
V
S
H
L
P
H
A
V
A
F
---
A
L
V
D
T
L
I
--
H
M
S
T
P
E
V
D
L
F
K
Y
P
G
G
G
F
K
D
F
----
T
R
I
A
---
K
---
S
D
P
I
M
W
R
D
I
F
-
L
E
N
K
E
N
V
M
K
A
I
E
G
F
E
K
S
L
N
H
L
K
E
L
I
V
R
E
A
E
E
E
L
V
E
Y
L
K
E
V
K
I
K
R
--------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
81.48
30%
-76
- C2 -
2G5C
1
?
A:
[4-278]
------------
V
L
I
V
G
V
G
F
M
G
G
S
F
A
K
S
L
R
R
S
G
F
K
----
G
----
K
I
Y
G
Y
D
I
N
P
E
--
S
I
S
K
A
V
D
-----------
L
G
I
I
------------
D
E
G
------------
T
T
S
I
A
K
-
V
E
D
F
S
P
D
F
V
M
L
S
S
--
P
-
V
-
R
--
T
F
--
R
-
E
I
---
A
K
---
K
-----
L
S
Y
I
-
L
S
E
D
A
-
T
V
T
-----
D
Q
G
S
-
V
K
-
G
K
L
V
Y
D
-
L
E
N
I
L
G
---
K
--
R
F
V
G
G
H
P
-
I
A
-
G
T
E
K
S
-
G
V
E
-
Y
S
L
D
N
L
Y
E
G
K
K
V
I
L
T
P
-
T
K
K
-
T
D
-------
K
K
R
L
--------
K
L
V
K
R
V
W
E
D
V
G
G
V
V
-
E
-
Y
M
S
P
E
L
H
--
D
Y
V
-
F
G
V
V
S
H
L
P
H
A
V
A
F
---
A
L
V
D
T
L
I
--
H
M
S
T
P
E
V
D
L
F
K
Y
P
G
G
G
F
K
D
F
-------
A
---
K
---
S
D
P
I
M
W
R
D
I
F
-
L
E
N
K
E
N
V
M
K
A
I
E
G
F
E
K
S
L
N
H
L
K
E
L
I
V
R
E
A
E
E
E
L
V
E
Y
L
K
E
V
K
I
K
R
--------------------------------------------------------------------------------------------------------------------
22
HHSearch
73.77
21%
-64
- C2 -
3KTD
2
?
A:
[8-339]
---------
S
R
P
V
C
I
L
G
L
G
L
I
G
G
S
L
L
R
D
L
H
A
A
--
N
----
H
----
S
V
F
G
Y
N
R
S
R
S
--
G
A
K
S
A
V
D
-----------
E
G
F
D
------------
V
S
A
D
L
----------
E
A
T
L
Q
R
-
A
A
A
-
E
D
A
L
I
V
L
A
V
--
P
-
M
-
T
A
-
I
D
--
S
-
L
L
---
D
A
---
V
-----
H
T
-
H
-
A
-
P
N
N
-
G
F
T
-----
D
V
V
S
-
V
K
-
T
A
V
Y
D
A
-
V
K
A
R
N
----
M
Q
H
R
Y
V
G
S
H
P
-
M
A
-
G
T
A
-
S
-
G
W
S
-
A
S
M
D
G
L
F
K
R
A
V
W
V
V
T
F
-
D
Q
L
F
D
G
TDIN
S
T
W
I
S
I
W
--------
K
D
V
V
Q
M
A
L
A
V
G
A
E
V
-
V
-
P
S
R
V
G
P
H
--
D
A
A
-
A
A
R
V
S
H
L
T
H
I
L
A
E
---
T
L
A
I
V
G
D
--
N
---
G
G
A
L
S
L
S
L
A
A
G
S
Y
R
D
S
----
T
R
V
A
---
G
---
T
D
P
G
L
V
R
A
M
C
-
E
S
N
A
G
P
L
V
K
A
L
D
E
A
L
A
I
L
H
E
A
R
E
G
L
T
A
E
Q
-
P
N
I
E
Q
L
A
D
N
G
Y
R
S
R
I
---------------------------------
R
Y
E
A
R
S
-
G
Q
--
S
S
R
P
V
L
R
L
H
P
G
T
P
N
W
E
K
Q
L
-
I
H
A
E
T
L
G
A
R
I
E
----------------------------------------
3
PsiBlast_PDB
72.91
32%
-54
- C2 -
4WJI
6
?
A:
[6-286]
-----------
T
I
A
L
I
G
I
G
L
I
G
S
S
I
A
R
D
I
R
E
K
Q
L
A
----
G
----
T
I
V
V
T
T
R
S
E
A
--
T
L
K
R
A
G
E
-----------
L
G
L
G
------------
D
R
Y
------------
T
L
S
A
A
E
-
A
V
E
-
G
A
D
L
V
V
V
S
V
--
P
-
V
-
G
A
-
S
G
--
A
-
V
A
---
A
E
---------
I
A
A
H
-
L
K
P
G
A
-
I
V
T
-----
D
V
G
S
-
T
K
-
G
S
V
I
A
Q
-
M
A
P
H
L
P
---
K
D
V
H
F
V
P
G
H
P
-
I
A
-
G
T
E
H
S
-
G
P
D
-
A
G
F
A
G
L
F
R
G
R
W
C
I
L
T
P
-
P
A
G
-
T
D
-------
E
E
A
V
--------
A
R
L
R
-
L
F
W
E
T
L
G
S
M
-
V
D
E
M
D
P
K
H
H
--
D
K
V
-
L
A
I
V
S
H
L
P
H
I
I
A
Y
---
N
I
V
G
T
A
D
D
L
E
T
V
T
E
S
E
V
I
-
K
Y
S
A
S
G
F
R
D
F
----
T
R
L
A
---
A
---
S
D
P
T
M
W
R
D
V
C
-
L
H
N
K
D
A
I
L
E
M
L
A
R
F
S
E
D
L
A
S
L
Q
R
A
I
R
W
G
D
G
D
K
L
F
D
L
F
T
R
T
R
A
I
R
R
---------------------------------
S
I
--------------------------------------------------------------------------------
1
PsiBlast_PDB
63.22
38%
-11
- C2 -
3DZB
-
?
A:
[5-298]
-----------
T
I
Y
I
A
G
L
G
L
I
G
G
S
L
A
L
G
I
K
R
D
H
P
D
----
Y
----
E
I
L
G
Y
N
R
S
D
Y
--
S
R
N
I
A
L
E
-----------
R
G
I
V
------------
D
R
A
------------
T
G
D
F
K
E
-
F
A
P
-
L
A
D
V
I
I
L
A
V
--
P
-
I
-
K
Q
-
T
M
--
A
-
Y
L
---
K
E
---
L
-----
A
D
L
D
-
L
K
D
N
V
-
I
I
T
-----
D
A
G
S
-
T
K
R
E
I
V
E
A
A
-
E
R
Y
L
T
G
---
K
N
V
Q
F
V
G
S
H
P
-
M
A
-
G
S
--------
A
A
D
V
T
L
F
E
N
A
Y
Y
I
F
T
P
-
T
S
L
-
T
K
-------
E
T
T
I
--------
P
E
L
K
D
I
L
S
G
L
K
S
R
Y
-
V
-
E
I
D
A
A
E
H
--
D
R
V
-
T
S
Q
I
S
H
F
P
H
L
L
A
S
---
G
L
M
E
Q
A
A
--
D
Y
A
Q
A
H
E
M
T
N
H
F
A
A
G
G
F
R
D
M
----
T
R
I
A
---
E
---
S
E
P
G
M
W
A
S
I
L
-
M
T
N
G
P
A
V
L
D
R
I
E
D
F
K
K
R
L
D
H
V
A
D
L
I
K
A
E
D
E
S
A
I
W
E
F
F
D
N
G
R
K
K
R
K
---------------------------------
E
M
E
I
H
K
K
G
G
V
E
S
A
F
--------------------------------------------------------------------
45
Fugue
61.00
20%
-71
- C2 -
2PV7
3
TYRA_HAEIN
A:
[13-292]
GFKTINSDI
H
K
I
V
I
V
G
G
Y
G
K
L
G
G
L
F
A
R
Y
L
R
--
A
S
G
----
Y
----
P
I
S
I
L
D
R
E
D
W
--
A
V
A
E
S
I
L
---------------------------------------------------
A
-
N
A
D
V
V
I
V
S
V
--
P
-
I
-
N
L
-
T
L
--
E
-
T
I
---
E
R
---
L
-----
K
P
Y
L
---
T
E
N
M
L
L
A
-----
D
L
T
S
-
V
K
-
R
E
P
L
A
K
M
L
E
---
V
---
H
T
G
A
V
L
G
L
H
P
M
F
G
-
A
D
I
A
S
M
A
-------------
K
Q
V
V
V
R
-
C
D
G
-
R
F
-------
P
E
R
Y
--------
E
W
L
L
E
Q
I
Q
I
W
G
A
K
I
-
Y
-
Q
T
N
A
T
E
H
--
D
H
N
M
T
Y
I
-
Q
A
L
R
H
F
S
T
F
---
A
N
G
L
H
L
S
--
K
Q
P
I
N
L
A
N
L
L
A
L
S
S
P
I
Y
R
L
E
L
A
M
I
G
R
L
F
---
A
---
Q
D
A
E
L
Y
A
D
I
I
M
N
------
L
A
V
I
E
T
L
K
Q
T
Y
D
E
A
L
T
F
F
E
N
N
D
R
Q
G
F
I
D
A
F
H
K
V
R
D
W
F
G
---------------------------------
D
Y
S
E
Q
F
L
K
E
S
R
Q
L
L
Q
Q
A
-----------------------------------------------------------------
41
HHSearch
57.75
16%
-83
* C2 *
3DOJ
1
GLYR1_ARATH
A:
[21-196]
---------
M
M
E
V
G
F
L
G
L
G
I
M
G
K
A
M
S
M
N
L
L
K
N
--
G
----
F
----
K
V
T
V
W
N
R
T
L
S
--
K
C
D
E
L
V
E
-----------
H
G
A
S
--------------
V
------------
C
E
S
P
A
E
-
V
I
K
-
K
C
K
Y
T
I
A
M
L
--
S
D
P
-
C
A
-
A
L
--
S
-
V
V
---
F
D
KGG
V
-----
L
E
-
Q
-
I
C
E
G
K
-
G
Y
I
-----
D
M
S
T
-
V
D
-
A
E
T
S
L
K
-
I
N
E
A
I
T
G
--
K
G
G
R
F
V
E
G
-
P
-
V
S
-
G
S
K
K
P
-
A
---------
E
D
G
Q
L
I
I
L
A
A
-
G
D
---
K
--------
A
L
F
--------
E
E
S
I
P
A
F
D
V
L
G
K
R
S
-
F
-
Y
L
G
Q
V
G
N
--
G
A
K
-
M
K
L
I
V
N
M
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
HHSearch
56.76
21%
-85
- C2 -
3ADO
-
CRYL1_RABIT
A:
[7-188]
----------
G
D
V
L
I
V
G
S
G
L
V
G
R
S
W
A
M
L
F
A
S
G
--
G
----
F
----
R
V
K
L
Y
D
I
E
P
R
--
Q
I
T
G
A
L
E
N
I
R
K
E
M
K
S
L
Q
Q
S
G
S
L
KGSLS
A
E
E
Q
L
S
L
I
S
S
------------
C
T
N
L
A
E
-
A
V
E
-
G
V
V
H
I
Q
E
C
V
--
P
-
E
-
N
L
-
D
L
K
R
K
-
I
F
---
A
Q
---
L
-----
D
S
-
I
-
V
D
D
R
V
-
V
L
S
-----
S
S
S
S
C
L
L
-
P
S
K
----
L
F
T
G
L
A
---
H
V
K
Q
C
I
V
A
H
P
-
V
N
-
P
P
Y
Y
--------------
I
P
L
V
E
L
V
P
-
H
P
E
T
S
P
--------
A
T
V
--------
D
R
T
H
A
L
M
R
K
I
G
Q
S
P
-
V
-
R
V
L
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
HHSearch
55.54
17%
-81
- C2 -
3OBB
5
SERDH_PSEAE
A:
[3-180]
---------
M
K
Q
I
A
F
I
G
L
G
H
M
G
A
P
M
A
T
N
L
L
K
A
--
G
----
Y
----
L
L
N
V
F
D
L
V
Q
S
--
A
V
D
G
L
V
A
-----------
A
G
A
S
--------------
A
------------
A
R
S
A
R
D
-
A
V
Q
-
G
A
D
V
V
I
S
M
L
--
P
-
A
-
S
Q
-
H
V
--
E
G
L
Y
LDD
D
G
---
L
-----
L
A
-
H
-
I
A
P
-
T
-
L
V
L
-----
E
C
S
T
-
I
A
-
P
T
S
A
R
K
-
I
H
A
A
A
R
E
--
R
G
L
A
M
L
D
-
A
P
-
V
S
-
G
G
T
A
G
--
A
--------
A
A
G
T
L
T
F
M
V
G
-
G
D
---
A
--------
E
A
L
--------
E
K
A
R
P
L
F
E
A
M
G
R
N
I
-
F
-
H
A
G
P
D
G
A
--
G
Q
V
-
A
K
V
C
N
N
Q
L
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
55.01
17%
-95
- C2 -
2RCY
4
?
A:
[4-239]
---------
N
I
K
L
G
F
M
G
L
G
Q
M
G
S
A
L
A
H
G
I
A
N
A
--
N
----
I
IKKE
N
L
F
Y
Y
G
P
S
K
K
--
N
T
-----------------
T
L
N
--------------
Y
------------
M
S
S
N
E
E
-
L
A
R
-
H
C
D
I
I
V
C
A
V
--
K
-
P
-
D
I
-
A
G
--
S
-
V
L
---
N
N
---
I
-----
K
P
-
Y
-
L
S
-
S
K
-
L
L
I
-------
S
I
-
C
G
-
G
L
N
I
G
K
-
L
E
E
M
V
G
---
S
E
N
K
I
V
W
V
M
P
-
N
T
-
P
C
L
V
G
------------
E
G
S
-
F
I
Y
C
S
-
N
K
N
V
N
S
--------
T
D
K
--------
K
Y
V
N
D
I
F
N
S
C
G
I
-
I
-
H
-
E
I
K
E
K
D
M
--
D
I
A
-
T
A
I
S
G
C
G
P
A
Y
V
Y
L
F
I
E
S
L
I
D
A
G
V
--
K
N
G
L
S
R
E
L
S
K
N
L
V
L
Q
T
I
K
G
S
----
V
E
M
V
K
K
S
D
---
Q
P
V
Q
Q
L
K
D
N
I
-
V
S
P
G
G
I
T
A
V
G
L
Y
S
L
E
K
------------------------------------------------------------------------------------------------------------------------------------------------
30
HHSearch
54.12
16%
-63
- C2 -
1YGY
1
SERA_MYCTU
A:
[143-514]
----------
K
T
V
G
V
V
G
L
G
R
I
G
Q
L
V
A
Q
R
I
A
A
F
--
G
----
A
----
Y
V
V
A
Y
D
P
Y
V
S
--
P
A
R
-
A
A
Q
-----------
L
G
I
E
---------------------------
L
L
S
L
D
D
-
L
L
A
-
R
A
D
F
I
S
V
H
L
--
P
-
K
-
T
P
E
T
A
--
G
-
L
I
D--
K
E
---
A
-----
L
A
-
K
-
T
K
P
G
V
-
I
I
V
-----
N
A
A
R
-
G
G
-
L
V
D
E
A
A
-
L
A
D
---------
A
I
T
G
G
H
V
-
R
A
A
G
L
D
V
F
-
A
T
E
P
C
T
D
S
P
L
F
E
L
A
Q
V
V
V
T
P
-
H
L
G
A
S
T
-------
A
E
A
Q
D
R
A
G
T
D
V
A
E
S
V
R
L
A
L
A
--
G
E
F
V
P
D
-
A
V
N
V
G
G
G
VV
N
E
E
-
V
A
P
W
L
D
L
V
----
R
---
K
L
G
V
L
A
G
--
V
L
S
D
E
L
P
V
---
S
L
S
V
Q
V
--
R
----
G
E
L
A
---
A
---
E
E
V
E
V
L
R
L
S
A
-------
L
R
G
L
F
S
A
V
I
E
D
A
V
T
F
V
N
A
P
A
L
A
A
E
R
G
V
T
A
E
I
C
K
A
S
E
S
P
N
HR
S
V
V
D
V
R
A
V
G
ADG
S
V
V
T
V
S
G
T
L
Y
G
PQLSQKIV
Q
I
N
G
R
H
F
D
L
R
A
Q
G
I
N
L
I
I
H
Y
V
D
R
P
G
A
L
G
K
I
G
T
L
L
G
T
A
G
V
N
I
Q
A
A
Q
L
S
E
D
A
E
G
P
G
A
T
I
L
L
R
L
D
Q
D
V
P
D
D
-
V
R
T
A
I
--------
52
Fugue
53.36
11%
-72
- C2 -
1EVY
1
GPDA_LEIME
A:
[9-357]
---KD
E
L
L
Y
L
N
K
A
V
V
F
G
S
G
A
F
G
T
A
L
A
M
V
L
--
S
K
K
C
----
R
----
E
V
C
V
W
H
M
N
E
E
--
E
V
R
L
V
N
E
-----------
K
R
E
N
------------
V
L
F
LKGVQLASN
I
T
F
T
S
D
V
E
K
-
A
Y
N
-
G
A
E
I
I
L
F
V
I
--
P
-
T
-
Q
F
-
L
R
--
G
-
F
F
---
E
K
---
S
G
G
N
L
I
A
Y
A
K
-
E
K
Q
V
P
-
V
L
V
C
T
K
G
I
E
R
S
T
-
L
K
-
F
P
A
E
I
I
-
G
E
F
L
P
S
---
P
L
L
S
V
L
A
G
P
S
-
F
-------------
A
I
E
V
A
T
G
V
F
T
C
V
S
I
A
-
S
A
---
D
-------
I
N
V
A
--------
R
R
L
Q
R
I
M
S
T
G
D
R
S
F
-
V
-
C
W
A
T
T
----
D
T
V
-
G
C
E
V
A
S
A
V
K
N
V
L
A
---
I
G
S
G
V
A
N
--
G
L
G
M
G
L
N
A
R
A
A
L
I
M
R
G
L
L
E
I
----
R
D
L
T
---
A
---
A
L
G
--
G
D
G
S
A
-
V
F
G
L
-----------
A
G
L
G
D
L
Q
L
T
C
S
S
E
L
S
R
N
F
T
V
G
K
K
L
G
K
G
L
P
I
---------------------------------
E
E
I
Q
R
A
V
A
E
G
V
A
T
A
D
P
L
M
R
L
A
K
Q
L
K
V
--
K
M
P
L
C
H
Q
I
Y
E
I
V
Y
K
K
K
N
P
R
D
A
L
A
D
L
L
S
C
--------
G
L
Q
D
E
G
L
P
P
L
F
K
------
31
HHSearch
52.21
17%
-74
- C2 -
2IZZ
5
P5CR1_HUMAN
A:
[22-267]
---------
S
M
S
V
G
F
I
G
A
G
Q
L
A
F
A
L
A
K
G
F
T
A
A
--
G
VLAA
H
----
K
I
M
A
S
S
P
D
M
D
L
A
T
V
S
A
L
R
K
-----------
M
G
V
K
------------
L
--------------
T
P
H
N
K
E
-
T
V
Q
-
H
S
D
V
L
F
L
A
V
--
K
-
P
-
H
I
-
I
P
--
F
-
I
L
---
D
E
---
I
-----
G
A
-
D
-
I
E
D
R
H
-
I
V
V
-----
S
C
A
A
-
G
V
-
T
--
I
S
S
-
I
E
K
K
L
S
A
F
R
P
A
P
R
V
I
R
C
M
T
-
N
T
-
P
V
V
V
R
------------
E
G
A
-
T
V
Y
A
T
-
G
T
H
A
Q
V
--------
E
D
G
--------
R
L
M
E
Q
L
L
S
S
V
G
F
-
C
-
T
-
E
V
E
E
D
L
I
--
D
A
V
-
T
G
L
S
G
S
G
P
A
Y
A
F
T
A
L
D
A
L
A
D
G
G
V
--
K
M
G
L
P
R
R
L
A
V
R
L
G
A
Q
A
L
L
G
A
----
A
K
M
L
---
L
H
SE
Q
H
P
G
Q
L
K
D
N
V
-
S
S
P
G
G
A
T
I
H
A
L
H
V
L
--------------------------------------------------------------------------------------------------------------------------------------------------
40
HHSearch
51.87
17%
-78
- C2 -
3QHA
-
?
A:
[11-185]
---------
Q
L
K
L
G
Y
I
G
L
G
N
M
G
A
P
M
A
T
R
M
T
E
W
--
P
----
G
----
G
V
T
V
Y
D
I
R
I
E
--
A
M
T
P
L
A
E
-----------
A
G
A
T
--------------
L
------------
A
D
S
V
A
D
--
V
A
-
A
A
D
L
I
H
I
T
V
--
L
-
D
D
A
Q
-
V
R
--
E
-
V
V
---
G
E
---
L
-----
A
G
-
H
-
A
K
P
G
T
-
V
I
A
-----
I
H
S
T
-
I
S
-
D
T
T
A
V
E
-
L
A
R
D
L
K
A--
R
D
I
H
I
V
D
A
-
P
-
V
S
-
G
G
A
A
A
------
A
----
A
R
G
E
L
A
T
M
V
G
-
A
D
---
R
--------
E
V
Y
--------
E
R
I
K
P
A
F
K
H
W
A
A
V
V
-
I
-
H
A
G
E
P
G
A
--
G
T
R
-
M
K
L
A
R
N
M
L
T
F
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
47
Fugue
51.84
14%
-67
- C2 -
3DOJ
1
GLYR1_ARATH
A:
[18-309]
------GSH
M
M
E
V
G
F
L
G
L
G
I
M
G
K
A
M
S
M
N
L
L
K
N
G
F
----------
K
V
T
V
W
N
R
T
L
S
--
K
C
D
E
L
V
E
-----------
H
G
A
--------------
S
V
------------
C
E
S
P
A
E
-
V
I
K
-
K
C
K
Y
T
I
A
M
L
SD
P
-
C
-
A
A
-
L
S
--
V
-
V
F
---
D
K
GG-
V
-----
L
E
Q
I
-
C
E
G
K
G
-
Y
I
D
-----
M
S
T
V
-
D
A
-
E
T
S
L
K
I
-
N
E
A
I
T
G
---
K
G
G
R
F
V
E
G
-
P
-
V
S
-
G
S
----------
K
K
P
A
E
D
G
Q
L
I
I
L
A
A
G
D
K
A
-
L
F
-------
E
E
S
I
--------
P
A
F
D
V
L
G
K
R
S
F
Y
L
G
-
Q
-
V
G
N
G
A
K
M
--
K
L
I
-
V
N
M
I
M
G
S
M
M
N
A
F
S
---
E
G
L
V
L
A
D
--
K
S
G
L
S
S
D
T
L
L
D
I
L
D
L
G
A
M
T
N
----
P
M
F
K
---
G
---
K
G
P
S
M
N
K
S
-
S
-
Y
P
P
A
F
P
L
K
H
Q
Q
K
D
M
R
L
A
L
A
L
G
D
E
N
---------------------------------------------------------
A
V
S
M
P
V
A
A
A
A
N
E
A
F
K
K
A
R
S
L
G
L
G
D
L
D
F
S
A
V
I
E
A
V
K
F
S
R
-----------------------------------------