@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SA2266: (2016-04-02 )
MTVLTDKIAVVTGAGSGIGEAIATLLHEEGAKVVLAGRNKDKLQNVANQLAQDSVKVVPTDVTNKEEVDELMKIAQQTFGGLDIVINSAGQMLSSKITDYQVDEWDSMIDVNIKGTLYTAQAALPTMLEQSSGHLINIASISGFEVTKSSTIYSATKAAVHTITQGLEKELAKTGVKVTSISPGMVDTAITAAYNPSDRKKLDPQDIAEAVLYALTQPKHVNVNEITVRPV
Atome Classification :
(24 SA)
.........10........20........30........40...--.....50-.----..---...--...--60........70........80........90....--....100........110.......120.......130.--........140.....--..-150--........160.......170-.--.......180....-.---------..190------------..-.--.-----------.-..----------200---------..-------------....-..210.......220.......230
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MTV
L
T
D
K
I
A
V
V
TGAGS
G
I
G
E
A
I
A
T
L
L
H
EEG
A
K
V
V
L
AGR
N
K
D
K
L
Q
--
N
V
A
N
Q
L
--
A
----QD---S
V
K
--
V
VP--TDVT
N
K
E
E
V
D
E
L
M
K
I
A
Q
Q
TFGG
L
D
I
V
INSA
G
Q
M
L
S
S
--KITDY-QVDEWD
S
M
I
D
V
N
I
K
G
T
L
Y
T
A
Q
A
A
L
P
T
M
L
E
Q--S--SG
H
L
I
N
I
A
S
IS
G
F
E
VT--KS-S-
T
--
I
Y
S
A
T
K
A
A
V
H
T
I
T
Q
G
L
E
K
E
L
--
A
--KTG
V
K
V
TSISPGM
V
-
D
---------
T
A
I
T
A------------AY-N--P-----------S-DR----------KK----------L
D
-------------
P
Q
D
I
-
A
E
A
V
L
Y
A
LTQPKHVNV
N
E
I
T
VRPV
36
PsiBlast_CBE
88.69
33%
-96
- C1 -
1XG5
2
DHR11_HUMAN
C:
[27-276]
M
E
R
W
R
D
R
L
A
L
V
T
G
A
S
G
G
I
G
A
A
V
A
R
A
L
V
Q
Q
G
L
K
V
V
G
C
A
R
T
V
G
N
I
E
--
E
L
A
A
E
C
--
K
----
S
A
---
G
Y
P
GT
L
I
P
YR
C
D
L
S
N
E
E
D
I
L
S
M
F
S
A
I
R
S
Q
H
S
G
V
D
I
C
I
N
N
A
G
L
A
R
P
D
--
T
L
L
S
G
-
S
T
S
G
W
K
D
M
F
N
V
N
V
L
A
L
S
I
C
T
R
E
A
Y
Q
S
M
K
E
R
--
N
VD
D
G
H
I
I
N
I
N
S
M
S
G
H
R
V
L
--
P
L
-
S
-
V
TH
F
Y
S
A
T
K
Y
A
V
T
A
L
T
E
G
L
R
Q
E
L
RE
A
--
Q
T
H
I
R
A
T
C
I
S
P
G
V
V
-
E
---------
T
Q
F
A
F
------------
K
L
-
H
--
D
-----------
K
-
D
P
----------
E
K
AAATYEQMKC
L
K
-------------
P
E
D
V
-
A
E
A
V
I
Y
V
L
S
T
P
A
H
I
Q
I
G
D
I
Q
M
R
P
-
8
PsiBlast_PDB
87.08
33%
-96
- C1 -
1XG5
2
DHR11_HUMAN
A:
[27-276]
M
E
R
W
R
D
R
L
A
L
V
T
G
A
S
G
G
I
G
A
A
V
A
R
A
L
V
Q
Q
G
L
K
V
V
G
C
A
R
T
V
G
N
I
E
--
E
L
A
A
E
C
--
K
----
S
A
---
G
Y
P
G
T
L
I
P
Y
R
C
D
L
S
N
E
E
D
I
L
S
M
F
S
A
I
R
S
Q
H
S
G
V
D
I
C
I
N
N
A
G
L
A
R
P
D
--
T
L
L
S
G
-
S
T
S
G
W
K
D
M
F
N
V
N
V
L
A
L
S
I
C
T
R
E
A
Y
Q
S
M
K
E
R
--
N
VD
D
G
H
I
I
N
I
N
S
M
S
G
H
R
V
L
--
P
L
-
S
-
V
T
H
F
Y
S
A
T
K
Y
A
V
T
A
L
T
E
G
L
R
Q
E
L
R
E
A
--
Q
T
H
I
R
A
T
C
I
S
P
G
V
V
-
E
---------
T
Q
F
A
F
------------
K
L
-
H
--
D
-----------
K
-
D
P
----------
E
K
A
A
A
T
Y
EC---
L
K
-------------
P
E
D
V
-
A
E
A
V
I
Y
V
L
S
T
P
A
H
I
Q
I
G
D
I
Q
M
R
P
-
3
PsiBlast_PDB
86.53
38%
-90
- C1 -
2JAP
2
?
A:
[3-243]
-
S
A
L
Q
G
K
V
A
L
I
T
G
A
S
S
G
I
G
E
A
T
A
R
A
L
A
A
E
G
A
A
V
A
I
A
A
R
R
V
E
K
L
R
--
A
L
G
D
E
L
T
A
A
----
G
A
---
K
V
H
--
V
L
E
--
L
D
V
A
D
R
Q
G
V
D
A
A
V
A
S
T
V
E
A
L
G
G
L
D
I
L
V
N
N
A
G
I
M
L
L
G
--
P
V
E
D
A
-
D
T
T
D
W
T
R
M
I
D
T
N
L
L
G
L
M
Y
M
T
R
A
A
L
P
H
L
L
-
R
--
S
--
K
G
T
V
V
Q
M
S
S
I
A
G
R
V
N
V
--
R
N
-
A
-
A
--
V
Y
Q
A
T
K
F
G
V
N
A
F
S
E
T
L
R
Q
E
V
--
T
--
E
R
G
V
R
V
V
V
I
E
P
G
T
T
-
D
---------
T
E
L
R
G
------------
H
I
-
T
--
H
T
A
T
K
E
M
Y
E
Q
R
I
S
-
Q
I
----------
R
K
----------
L
Q
-------------
A
Q
D
I
-
A
E
A
V
R
Y
A
V
T
A
P
H
H
A
T
V
H
E
I
F
I
R
P
-
124
HHSearch
86.36
35%
-84
- C1 -
1XG5
2
DHR11_HUMAN
A:
[28-276]
-
E
R
W
R
D
R
L
A
L
V
T
G
A
S
G
G
I
G
A
A
V
A
R
A
L
V
Q
Q
G
L
K
V
V
G
C
A
R
T
V
G
N
I
E
--
E
L
A
A
E
C
--
K
S
A
GY
P
G
---
T
L
I
--
P
Y
R
--
C
D
L
S
N
E
E
D
I
L
S
M
F
S
A
I
R
S
Q
H
S
G
V
D
I
C
I
N
N
A
G
L
A
R
P
D
--
T
L
L
S
G
-
S
T
S
G
W
K
D
M
F
N
V
N
V
L
A
L
S
I
C
T
R
E
A
Y
Q
S
M
K
E
R
NV
D
--
D
G
H
I
I
N
I
N
S
M
S
G
H
R
V
L
PL
S
V
-
T
-
H
--
F
Y
S
A
T
K
Y
A
V
T
A
L
T
E
G
L
R
Q
E
L
--
R
E
A
Q
T
H
I
R
A
T
C
I
S
P
G
V
V
-
E
---------
T
Q
F
A
F
------------
K
L
H
D
KD
P
E
K
A
A
A
T
Y
----
E
--------------
C
----------
L
K
-------------
P
E
D
V
-
A
E
A
V
I
Y
V
L
S
T
P
A
H
I
Q
I
G
D
I
Q
M
R
P
-
30
PsiBlast_CBE
86.10
38%
-89
- C1 -
2JAP
2
?
B:
[3-243]
-
S
A
L
Q
G
K
V
A
L
I
T
G
A
S
S
G
I
G
E
A
T
A
R
A
L
A
A
E
G
A
A
V
A
I
A
A
R
R
V
E
K
L
R
--
A
L
G
D
E
L
T
A
A
----
G
A
---
K
V
H
--
V
L
E
--
L
D
V
A
D
R
Q
G
V
D
A
A
V
A
S
T
V
E
A
L
G
G
L
D
I
L
V
N
N
A
G
I
M
L
L
G
--
P
V
E
D
A
-
D
T
T
D
W
T
R
M
I
D
T
N
L
L
G
L
M
Y
M
T
R
A
A
L
P
H
L
L
-
R
--
S
--
K
G
T
V
V
Q
M
S
S
I
A
G
R
V
N
V
--
R
N
-
A
-
A
--
V
Y
Q
A
T
K
F
G
V
N
A
F
S
E
T
L
R
Q
E
V
--
T
--
E
R
G
V
R
V
V
V
I
E
P
G
T
T
-
D
---------
T
E
L
R
G
------------
H
I
-
T
--
H
T
A
T
K
E
M
Y
E
Q
R
I
S
-
Q
I
----------
R
K
----------
L
Q
-------------
A
Q
D
I
-
A
E
A
V
R
Y
A
V
T
A
P
H
H
A
T
V
H
E
I
F
I
R
P
-
35
PsiBlast_CBE
86.01
33%
-94
- C1 -
1XG5
2
DHR11_HUMAN
D:
[27-276]
M
E
R
W
R
D
R
L
A
L
V
T
G
A
S
G
G
I
G
A
A
V
A
R
A
L
V
Q
Q
G
L
K
V
V
G
C
A
R
T
V
G
N
I
E
--
E
L
A
A
E
C
--
K
----
S
A
---
G
Y
P
GT
L
I
P
YR
C
D
L
S
N
E
E
D
I
L
S
M
F
S
A
I
R
S
Q
H
S
G
V
D
I
C
I
N
N
A
G
L
A
R
P
D
--
T
L
L
S
G
-
S
T
S
G
W
K
D
M
F
N
V
N
V
L
A
L
S
I
C
T
R
E
A
Y
Q
S
M
K
E
R
--
N
VD
D
G
H
I
I
N
I
N
S
M
S
G
H
R
V
L
--
P
L
-
S
-
V
TH
F
Y
S
A
T
K
Y
A
V
T
A
L
T
E
G
L
R
Q
E
L
RE
A
--
Q
T
H
I
R
A
T
C
I
S
P
G
V
V
-
E
---------
T
Q
F
A
F
------------
K
L
-
H
--
D
-----------
K
-
D
P
----------
E
K
AAATYEQMKC
L
K
-------------
P
E
D
V
-
A
E
A
V
I
Y
V
L
S
T
P
A
H
I
Q
I
G
D
I
Q
M
R
P
-
28
PsiBlast_CBE
85.87
38%
-89
- C1 -
2JAP
2
?
D:
[3-243]
-
S
A
L
Q
G
K
V
A
L
I
T
G
A
S
S
G
I
G
E
A
T
A
R
A
L
A
A
E
G
A
A
V
A
I
A
A
R
R
V
E
K
L
R
--
A
L
G
D
E
L
TA
A
----
G
A
---
K
V
H
--
V
L
E
--
L
D
V
A
D
R
Q
G
V
D
A
A
V
A
S
T
V
E
A
L
G
G
L
D
I
L
V
N
N
A
G
I
M
L
L
G
--
P
V
E
D
A
-
D
T
T
D
W
T
R
M
I
D
T
N
L
L
G
L
M
Y
M
T
R
A
A
L
P
H
L
L
-
R
--
S
--
K
G
T
V
V
Q
M
S
S
I
A
G
R
V
N
V
--
R
N
-
A
-
A
--
V
Y
Q
A
T
K
F
G
V
N
A
F
S
E
T
L
R
Q
E
V
--
T
--
E
R
G
V
R
V
V
V
I
E
P
G
T
T
-
D
---------
T
E
L
R
G
------------
H
I
-
T
--
H
TATKEMYEQRI
S
-
Q
I
----------
R
K
----------
L
Q
-------------
A
Q
D
I
-
A
E
A
V
R
Y
A
V
T
A
P
H
H
A
T
V
H
E
I
F
I
R
P
-
6
PsiBlast_PDB
85.66
38%
-90
- C1 -
2JAH
1
?
A:
[3-243]
-
S
A
L
Q
G
K
V
A
L
I
T
G
A
S
S
G
I
G
E
A
T
A
R
A
L
A
A
E
G
A
A
V
A
I
A
A
R
R
V
E
K
L
R
--
A
L
G
D
E
L
T
A
A
----
G
A
---
K
V
H
--
V
L
E
--
L
D
V
A
D
R
Q
G
V
D
A
A
V
A
S
T
V
E
A
L
G
G
L
D
I
L
V
N
N
A
G
I
M
L
L
G
--
P
V
E
D
A
-
D
T
T
D
W
T
R
M
I
D
T
N
L
L
G
L
M
Y
M
T
R
A
A
L
P
H
L
L
-
R
--
S
--
K
G
T
V
V
Q
M
S
S
I
A
G
R
V
N
V
--
R
N
-
A
-
A
--
V
Y
Q
A
T
K
F
G
V
N
A
F
S
E
T
L
R
Q
E
V
--
T
--
E
R
G
V
R
V
V
V
I
E
P
G
T
T
-
D
TELRGHITH
T
A
T
K
E
------------
M
Y
-
E
--
Q
R
I
---------
S
-
Q
I
----------
R
K
----------
L
Q
-------------
A
Q
D
I
-
A
E
A
V
R
Y
A
V
T
A
P
H
H
A
T
V
H
E
I
F
I
R
P
-
37
PsiBlast_CBE
85.14
33%
-100
- C1 -
1XG5
1
DHR11_HUMAN
B:
[27-276]
M
E
R
W
R
D
R
L
A
L
V
T
G
A
S
G
G
I
G
A
A
V
A
R
A
L
V
Q
Q
G
L
K
V
V
G
C
A
R
T
V
G
N
I
E
--
E
L
A
A
E
C
--
K
----
S
A
---
G
Y
P
GT
L
I
P
YR
C
D
L
S
N
E
E
D
I
L
S
M
F
S
A
I
R
S
Q
H
S
G
V
D
I
C
I
N
N
A
G
L
A
R
P
D
--
T
L
L
S
G
-
S
T
S
G
W
K
D
M
F
N
V
N
V
L
A
L
S
I
C
T
R
E
A
Y
Q
S
M
K
E
R
--
N
VD
D
G
H
I
I
N
I
N
S
M
S
G
H
R
V
L
--
P
L
-
S
-
V
TH
F
Y
S
A
T
K
Y
A
V
T
A
L
T
E
G
L
R
Q
E
L
RE
A
--
Q
T
H
I
R
A
T
C
I
S
P
G
V
V
-
E
---------
T
Q
F
A
F
------------
K
L
-
H
------------------------------MKC-------
L
K
-------------
P
E
D
V
-
A
E
A
V
I
Y
V
L
S
T
P
A
H
I
Q
I
G
D
I
Q
M
R
P
-
29
PsiBlast_CBE
85.06
38%
-89
- C1 -
2JAP
2
?
C:
[3-243]
-
S
A
L
Q
G
K
V
A
L
I
T
G
A
S
S
G
I
G
E
A
T
A
R
A
L
A
A
E
G
A
A
V
A
I
A
A
R
R
V
E
K
L
R
--
A
L
G
D
E
L
TA
A
----
G
A
---
K
V
H
--
V
L
E
--
L
D
V
A
D
R
Q
G
V
D
A
A
V
A
S
T
V
E
A
L
G
G
L
D
I
L
V
N
N
A
G
I
M
L
L
G
--
P
V
E
D
A
-
D
T
T
D
W
T
R
M
I
D
T
N
L
L
G
L
M
Y
M
T
R
A
A
L
P
H
L
L
-
R
--
S
--
K
G
T
V
V
Q
M
S
S
I
A
G
R
V
N
V
--
R
N
-
A
-
A
--
V
Y
Q
A
T
K
F
G
V
N
A
F
S
E
T
L
R
Q
E
V
--
T
--
E
R
G
V
R
V
V
V
I
E
P
G
T
T
-
D
---------
T
E
L
R
G
------------
H
I
-
T
--
H
TATKEMYEQRI
S
-
Q
I
----------
R
K
----------
L
Q
-------------
A
Q
D
I
-
A
E
A
V
R
Y
A
V
T
A
P
H
H
A
T
V
H
E
I
F
I
R
P
-
23
PsiBlast_CBE
83.75
34%
-93
- C1 -
3ASV
2
?
F:
[2-236]
-------
I
V
L
V
T
G
A
T
A
G
F
G
E
C
I
T
R
R
F
I
Q
Q
G
H
K
V
I
A
T
G
R
R
Q
E
R
L
Q
--
E
L
K
D
E
L
--
G
-----
D
---
N
L
Y
--
I
A
Q
--
L
D
V
R
N
R
A
A
I
E
E
M
L
A
S
L
P
A
E
W
C
N
I
D
I
L
V
N
N
A
G
L
A
L
G
M
--
E
P
A
H
K
A
S
V
E
D
W
E
T
M
I
D
T
N
N
K
G
L
V
Y
M
T
R
A
V
L
P
G
M
V
E
R
--
N
--
H
G
H
I
I
N
I
G
S
T
A
G
S
W
P
Y
--
A
G
-
G
-
N
--
V
Y
G
A
T
K
A
F
V
R
Q
F
S
L
N
L
R
T
D
L
--
H
--
G
T
A
V
R
V
T
D
I
E
P
G
L
V
G
G
---------
T
E
F
S
N
------------
V
R
-
F
--
K
-----------
G
-
D
D
----------
G
K
AEKTYQNTVA
L
T
-------------
P
E
D
V
-
S
E
A
V
W
W
V
S
T
L
P
A
H
V
N
I
N
T
L
E
M
M
P
V
25
PsiBlast_CBE
81.06
34%
-90
- C1 -
3ASV
2
?
D:
[2-236]
-------
I
V
L
V
T
G
A
T
A
G
F
G
E
C
I
T
R
R
F
I
Q
Q
G
H
K
V
I
A
T
G
R
R
Q
E
R
L
Q
--
E
L
K
D
E
L
--
G
-----
D
---
N
L
Y
--
I
A
Q
--
L
D
V
R
N
R
A
A
I
E
E
M
L
A
S
L
P
A
E
W
C
N
I
D
I
L
V
N
N
A
G
L
A
L
G
M
--
E
P
A
H
K
A
S
V
E
D
W
E
T
M
I
D
T
N
N
K
G
L
V
Y
M
T
R
A
V
L
P
G
M
V
E
R
--
N
--
H
G
H
I
I
N
I
G
S
T
A
G
S
W
P
Y
--
A
G
-
G
-
N
--
V
Y
G
A
T
K
A
F
V
R
Q
F
S
L
N
L
R
T
D
L
--
H
--
G
T
A
V
R
V
T
D
I
E
P
G
L
V
G
G
---------
T
E
F
S
N
------------
V
R
-
F
--
K
-----------
G
-
D
D
----------
G
K
AEKTYQNTVA
L
T
-------------
P
E
D
V
-
S
E
A
V
W
W
V
S
T
L
P
A
H
V
N
I
N
T
L
E
M
M
P
V
112
HHSearch
80.50
32%
-87
- C1 -
2BGK
-
SILD_PODPE
A:
[11-248]
T
N
R
L
Q
D
K
V
A
I
I
T
G
G
A
G
G
I
G
E
T
T
A
K
L
F
V
R
Y
G
A
K
V
V
I
A
D
I
A
D
D
H
G
Q
--
K
V
C
N
N
I
--
G
S---
P
D
---
V
I
S
--
F
V
H
--
C
D
V
T
K
D
E
D
V
R
N
L
V
D
T
T
I
A
K
H
G
K
L
D
I
M
F
G
N
V
G
V
L
S
T
T
PY
S
I
L
E
A
-
G
N
E
D
F
K
R
V
M
D
I
N
V
Y
G
A
F
L
V
A
K
H
A
A
R
V
M
I
P
A
--
K
--
K
G
S
I
V
F
T
A
S
I
S
S
F
T
A
G
--
E
G
V
S
-
H
--
V
Y
T
A
T
K
H
A
V
L
G
L
T
T
S
L
C
T
E
L
--
G
--
E
Y
G
I
R
V
N
C
V
S
P
Y
I
V
-
A
---------
S
P
L
L
T
------------
D
V
F
G
VD
S
S
R
V
E
E
L
A
H
Q
A
A
N
L
K
G
----------
T
L
----------
L
R
-------------
A
E
D
V
-
A
D
A
V
A
Y
L
A
G
D
E
S
------------
2
PsiBlast_PDB
80.39
34%
-89
- C1 -
3ASV
2
?
A:
[2-236]
-------
I
V
L
V
T
G
A
T
A
G
F
G
E
C
I
T
R
R
F
I
Q
Q
G
H
K
V
I
A
T
G
R
R
Q
E
R
L
Q
--
E
L
K
D
E
L
--
G
-----
D
---
N
L
Y
--
I
A
Q
--
L
D
V
R
N
R
A
A
I
E
E
M
L
A
S
L
P
A
E
W
C
N
I
D
I
L
V
N
N
A
G
L
A
L
G
M
--
E
P
A
H
K
A
S
V
E
D
W
E
T
M
I
D
T
N
N
K
G
L
V
Y
M
T
R
A
V
L
P
G
M
V
E
R
--
N
--
H
G
H
I
I
N
I
G
S
T
A
G
S
W
P
Y
--
A
G
-
G
-
N
--
V
Y
G
A
T
K
A
F
V
R
Q
F
S
L
N
L
R
T
D
L
--
H
--
G
T
A
V
R
V
T
D
I
E
P
G
L
V
G
G
---------
T
E
F
S
N
------------
V
R
-
F
--
K
-----------
G
-
D
D
----------
G
K
A
E
K
T
YQNTVA
L
T
-------------
P
E
D
V
-
S
E
A
V
W
W
V
S
T
L
P
A
H
V
N
I
N
T
L
E
M
M
P
V
32
PsiBlast_CBE
80.37
35%
-87
- C1 -
3P19
1
?
C:
[17-248]
------
K
L
V
V
I
T
G
A
S
S
G
I
G
E
A
I
A
R
R
F
S
E
E
G
H
P
L
L
L
L
A
R
R
V
E
R
L
K
AL
N
L
P
N
T
L
--
C
----
A
Q
-------------
V
D
V
T
D
K
Y
T
F
D
T
A
I
T
R
A
E
K
I
Y
G
P
A
D
A
I
V
N
N
A
G
M
M
L
L
G
--
Q
I
D
T
Q
-
E
A
N
E
W
Q
R
M
F
D
V
N
V
L
G
L
L
N
G
M
Q
A
V
L
A
P
M
K
A
R
--
N
--
C
G
T
I
I
N
I
S
S
I
A
G
K
K
T
F
--
P
D
-
H
-
A
--
A
Y
C
G
T
K
F
A
V
H
A
I
S
E
N
V
R
E
E
V
--
A
--
A
S
N
V
R
V
M
T
I
A
P
S
A
V
-
K
---------
T
E
L
L
S
---------------------------------
G
----------
G
V
----------
L
A
-------------
A
D
D
V
-
A
R
A
V
L
F
A
Y
Q
Q
P
Q
N
V
C
I
R
E
I
A
L
A
P
-
26
PsiBlast_CBE
80.32
34%
-90
- C1 -
3ASV
2
?
C:
[2-236]
-------
I
V
L
V
T
G
A
T
A
G
F
G
E
C
I
T
R
R
F
I
Q
Q
G
H
K
V
I
A
T
G
R
R
Q
E
R
L
Q
--
E
L
K
D
E
L
--
G
-----
D
---
N
L
Y
--
I
A
Q
--
L
D
V
R
N
R
A
A
I
E
E
M
L
A
S
L
P
A
E
W
C
N
I
D
I
L
V
N
N
A
G
L
A
L
G
M
--
E
P
A
H
K
A
S
V
E
D
W
E
T
M
I
D
T
N
N
K
G
L
V
Y
M
T
R
A
V
L
P
G
M
V
E
R
--
N
--
H
G
H
I
I
N
I
G
S
T
A
G
S
W
P
Y
--
A
G
-
G
-
N
--
V
Y
G
A
T
K
A
F
V
R
Q
F
S
L
N
L
R
T
D
L
--
H
--
G
T
A
V
R
V
T
D
I
E
P
G
L
V
G
G
---------
T
E
F
S
N
------------
V
R
-
F
--
K
-----------
G
-
D
D
----------
G
K
AEKTYQNTVA
L
T
-------------
P
E
D
V
-
S
E
A
V
W
W
V
S
T
L
P
A
H
V
N
I
N
T
L
E
M
M
P
V
19
PsiBlast_PDB
80.26
33%
-86
- C1 -
1VL8
2
?
A:
[19-253]
---
L
R
G
R
V
A
L
V
T
G
G
S
R
G
L
G
F
G
I
A
Q
G
L
A
E
A
G
C
S
V
V
V
A
S
R
N
L
E
E
A
S
--
E
A
A
Q
K
L
--
T
----
E
K
YG
V
E
T
M
--
A
F
R
--
C
D
V
S
N
Y
E
E
V
K
K
L
L
E
A
V
K
E
K
F
G
K
L
D
T
V
V
N
A
A
G
I
N
R
R
H
--
P
A
E
E
F
-
P
L
D
E
F
R
Q
V
I
E
V
N
L
F
G
T
Y
Y
V
C
R
E
A
F
S
L
L
R
E
S
--
D
--
N
P
S
I
I
N
I
G
S
L
T
V
E
E
V
T
--
M
P
-
N
I
S
--
A
Y
A
A
S
K
G
G
V
A
S
L
T
K
A
L
A
K
E
W
--
G
--
R
Y
G
I
R
V
N
V
I
A
P
G
W
Y
-
R
---------
T
K
M
T
E
------------
A
V
-
F
--------------
S
-
D
P
----------
E
K
----------
L
D
Y
M
L
K
R
IPLG
R
T
G
V
P
E
D
L
K
G
V
A
V
F
L
A
S
E
E
A
K
Y
V
----------
59
PsiBlast_CBE
80.03
33%
-85
- C1 -
1VL8
3
?
B:
[19-253]
---
L
R
G
R
V
A
L
V
T
G
G
S
R
G
L
G
F
G
I
A
Q
G
L
A
E
A
G
C
S
V
V
V
A
S
R
N
L
E
E
A
S
--
E
A
A
Q
K
L
--
T
----
E
K
YG
V
E
T
M
--
A
F
R
--
C
D
V
S
N
Y
E
E
V
K
K
L
L
E
A
V
K
E
K
F
G
K
L
D
T
V
V
N
A
A
G
I
N
R
R
H
--
P
A
E
E
F
-
P
L
D
E
F
R
Q
V
I
E
V
N
L
F
G
T
Y
Y
V
C
R
E
A
F
S
L
L
R
E
S
--
D
--
N
P
S
I
I
N
I
G
S
L
T
V
E
E
V
T
--
M
P
-
N
I
S
--
A
Y
A
A
S
K
G
G
V
A
S
L
T
K
A
L
A
K
E
W
--
G
--
R
Y
G
I
R
V
N
V
I
A
P
G
W
Y
-
R
---------
T
K
M
T
E
------------
A
V
-
F
--------------
S
-
D
P
----------
E
K
----------
L
D
Y
M
L
K
R
IPLG
R
T
G
V
P
E
D
L
K
G
V
A
V
F
L
A
S
E
E
A
K
Y
V
----------
33
PsiBlast_CBE
79.60
35%
-88
- C1 -
3P19
1
?
B:
[17-248]
------
K
L
V
V
I
T
G
A
S
S
G
I
G
E
A
I
A
R
R
F
S
E
E
G
H
P
L
L
L
L
A
R
R
V
E
R
L
K
A
L
N
L
P
N
T
L
--
C
----
A
Q
-------------
V
D
V
T
D
K
Y
T
F
D
T
A
I
T
R
A
E
K
I
Y
G
P
A
D
A
I
V
N
N
A
G
M
M
L
L
G
--
Q
I
D
T
Q
-
E
A
N
E
W
Q
R
M
F
D
V
N
V
L
G
L
L
N
G
M
Q
A
V
L
A
P
M
K
A
R
--
N
--
C
G
T
I
I
N
I
S
S
I
A
G
K
K
T
F
--
P
D
-
H
-
A
--
A
Y
C
G
T
K
F
A
V
H
A
I
S
E
N
V
R
E
E
V
--
A
--
A
S
N
V
R
V
M
T
I
A
P
S
A
V
-
K
---------
T
E
L
L
S
---------------------------------
G
----------
G
V
----------
L
A
-------------
A
D
D
V
-
A
R
A
V
L
F
A
Y
Q
Q
P
Q
N
V
C
I
R
E
I
A
L
A
P
-
24
PsiBlast_CBE
79.46
34%
-87
- C1 -
3ASV
2
?
E:
[2-236]
-------
I
V
L
V
T
G
A
T
A
G
F
G
E
C
I
T
R
R
F
I
Q
Q
G
H
K
V
I
A
T
G
R
R
Q
E
R
L
Q
--
E
L
K
D
E
L
--
G
-----
D
---
N
L
Y
--
I
A
Q
--
L
D
V
R
N
R
A
A
I
E
E
M
L
A
S
L
P
A
E
W
C
N
I
D
I
L
V
N
N
A
G
L
A
L
G
M
--
E
P
A
H
K
A
S
V
E
D
W
E
T
M
I
D
T
N
N
K
G
L
V
Y
M
T
R
A
V
L
P
G
M
V
E
R
--
N
--
H
G
H
I
I
N
I
G
S
T
A
G
S
W
P
Y
--
A
G
-
G
-
N
--
V
Y
G
A
T
K
A
F
V
R
Q
F
S
L
N
L
R
T
D
L
--
H
--
G
T
A
V
R
V
T
D
I
E
P
G
L
V
G
G
---------
T
E
F
S
N
------------
V
R
-
F
--
K
-----------
G
-
D
D
----------
G
K
AEKTYQNTVA
L
T
-------------
P
E
D
V
-
S
E
A
V
W
W
V
S
T
L
P
A
H
V
N
I
N
T
L
E
M
M
P
V
31
PsiBlast_CBE
78.50
35%
-85
- C1 -
3P19
1
?
D:
[17-248]
------
K
L
V
V
I
T
G
A
S
S
G
I
G
E
A
I
A
R
R
F
S
E
E
G
H
P
L
L
L
L
A
R
R
V
E
R
L
K
AL
N
L
P
N
T
L
--
C
----
A
Q
-------------
V
D
V
T
D
K
Y
T
F
D
T
A
I
T
R
A
E
K
I
Y
G
P
A
D
A
I
V
N
N
A
G
M
M
L
L
G
--
Q
I
D
T
Q
-
E
A
N
E
W
Q
R
M
F
D
V
N
V
L
G
L
L
N
G
M
Q
A
V
L
A
P
M
K
A
R
--
N
--
C
G
T
I
I
N
I
S
S
I
A
G
K
K
T
F
--
P
D
-
H
-
A
--
A
Y
C
G
T
K
F
A
V
H
A
I
S
E
N
V
R
E
E
V
--
A
--
A
S
N
V
R
V
M
T
I
A
P
S
A
V
-
K
---------
T
E
L
L
S
HTTSQQIKDGYD
A
W
-
R
--
V
-----------
D
-
M
G
----------
G
V
----------
L
A
-------------
A
D
D
V
-
A
R
A
V
L
F
A
Y
Q
Q
P
Q
N
V
C
I
R
E
I
A
L
A
P
-
4
PsiBlast_PDB
77.03
35%
-85
- C1 -
3P19
1
?
A:
[17-248]
------
K
L
V
V
I
T
G
A
S
S
G
I
G
E
A
I
A
R
R
F
S
E
E
G
H
P
L
L
L
L
A
R
R
V
E
R
L
K
A
L
N
L
P
N
T
L
--
C
----
A
Q
-------------
V
D
V
T
D
K
Y
T
F
D
T
A
I
T
R
A
E
K
I
Y
G
P
A
D
A
I
V
N
N
A
G
M
M
L
L
G
--
Q
I
D
T
Q
-
E
A
N
E
W
Q
R
M
F
D
V
N
V
L
G
L
L
N
G
M
Q
A
V
L
A
P
M
K
A
R
--
N
--
C
G
T
I
I
N
I
S
S
I
A
G
K
K
T
F
--
P
D
-
H
-
A
--
A
Y
C
G
T
K
F
A
V
H
A
I
S
E
N
V
R
E
E
V
--
A
--
A
S
N
V
R
V
M
T
I
A
P
S
A
V
-
K
---------
T
E
L
L
S
HTTS
Q
Q
I
K
D
G
Y
D
A
W
-
R
--
V
-----------
D
-
M
G
----------
G
V
----------
L
A
-------------
A
D
D
V
-
A
R
A
V
L
F
A
Y
Q
Q
P
Q
N
V
C
I
R
E
I
A
L
A
P
-
48
PsiBlast_CBE
71.21
32%
-86
- C1 -
3RRO
13
FABG_VIBCH
B:
[10-233]
---
L
E
G
K
V
A
L
V
T
G
A
S
R
G
I
G
K
A
I
A
E
L
L
A
E
R
G
A
K
V
I
G
T
A
T
S
E
S
G
A
Q
--
A
I
S
D
Y
L
--
G
-----
D
---
N
G
K
--
G
M
A
--
L
N
V
T
N
P
E
S
I
E
A
V
L
K
A
I
T
D
E
F
G
G
V
D
I
L
V
N
N
A
G
I
T
R
D
N
--
L
L
M
R
M
-
K
E
E
E
W
S
D
I
M
E
T
N
L
T
S
I
F
R
L
S
K
A
V
L
R
G
M
M
K
K
--
R
--
Q
G
R
I
I
N
V
G
S
V
V
G
T
M
G
N
--
A
G
-
Q
-
A
--
N
Y
A
A
A
K
A
G
V
I
G
F
T
K
S
M
A
R
E
V
--
A
--
S
R
G
V
T
V
N
T
V
A
P
G
F
I
-
E
---------
T
D
M
T
K
------------
A
L
-
N
--
D
-----------
E
-
Q
R
TATLAQVPAG
R
L
----------
G
D
-------------
P
R
E
I
-
A
S
A
V
A
F
-
L
A
S
P
E
------------
13
PsiBlast_PDB
70.66
32%
-83
- C1 -
3RRO
11
FABG_VIBCH
A:
[10-233]
---
L
E
G
K
V
A
L
V
T
G
A
S
R
G
I
G
K
A
I
A
E
L
L
A
E
R
G
A
K
V
I
G
T
A
T
S
E
S
G
A
Q
--
A
I
S
D
Y
L
--
G
-----
D
---
N
G
K
--
G
M
A
--
L
N
V
T
N
P
E
S
I
E
A
V
L
K
A
I
T
D
E
F
G
G
V
D
I
L
V
N
N
A
G
I
T
R
D
N
--
L
L
M
R
M
-
K
E
E
E
W
S
D
I
M
E
T
N
L
T
S
I
F
R
L
S
K
A
V
L
R
G
M
M
K
K
--
R
--
Q
G
R
I
I
N
V
G
S
V
V
G
T
M
G
N
--
A
G
-
Q
-
A
--
N
Y
A
A
A
K
A
G
V
I
G
F
T
K
S
M
A
R
E
V
--
A
--
S
R
G
V
T
V
N
T
V
A
P
G
F
I
-
E
---------
T
D
M
T
K
------------
A
L
-
N
--
D
-----------
E
-
Q
R
T
A
T
L
A
Q
VPAG
R
L
----------
G
D
-------------
P
R
E
I
-
A
S
A
V
A
F
-
L
A
S
P
E
------------