@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : jhp_0923: (2015-12-19 )
MAKTETDNFNKQDKHKLDYRKINYESKEIDDGKFIRIGDEVNHIFIEKAKINRGYLQNPKHKRTWWSLWLYKKPSDDALDIKVLDVFDDGKYTYFRYDRDQAFSKFPYTYKVVDGYDNPINSRVVGNYIIAEDISKKWTLRSGKEYVCVRRDKRKYQKSRDFMRLKRLLEQDEAMKAKRNNMHLIEDTTPQPKNAISVTELLAQIKNQTPSKECRALNEEEVKTLEEVKNIIKTPKPLQKDLKKNAKKHTIKTQYCVPIPYIERLKTTDGLEKHQKGLNNTKKQIQANPIEEIKENKK
Atome Classification :
(20 SA)
------...-......10...-....---.20--------------.......-.30........40...----.....50.-......-.----60........70--.-.....-----.------.80........-90...-...-----..100.------------..-.....110-.--.-..--...120-----....---...130.....------------..140----.......150-.......160......--------.170.......-----------------------180.......190........200.....-..210.......220.-......230-----....-..--------.240.......250.......260.-......270-.......280......-.290---.....-..-
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
------MAK-TETDNFNK
Q
D
K
-HKLD---
Y
R
K--------------INYESKE-IDDG
K
F
I
R
IGDEV
N
H
I
----
F
I
E
K
AKIN-RGYLQN-P----KHK
R
T
W
W
S
L
W
L
Y
--K-KPSDD-----A------L
D
I
K
V
L
D
V
FDD-G
K
Y
T
Y
-
F
R
Y-----DRDQ-A------------FS-KF
P
Y
T
Y
K
V-V--D-GY--DNPINS-----
R
V
VG---
N
Y
I
I
A
E
DISK
K
------------
W
TLRS----GK
E
Y
V
C
V
R
R
D
-
K
R
K
Y
Q
K
S
R
D
F
M
R
L
K
R
L
--------
L
E
Q
D
E
A
M
K
AKR-----------------------NN
M
H
L
IEDTTP-QPKNA
I
S
V
T
E
L
L
A
Q
I
KN-QTP
S
K
E
C
RAL
N
E
E
E
V
K
-
T
L
E
E
V
K
N
I
I-----KT
P
K
-
P
L
--------
Q
K
D
L
K
KNAKKH
T
I
KTQYCVP
I
P
Y
I
E
-
R
LKTTD
G
L
E
-
K
H
Q
K
GLN
N
T
K
K
QIQAN-
P
I
E
----
E
I
KEN-KK-
18
Fugue
79.74
15%
18
- C5 -
1JFA
2
TRI5_FUSSP
A:
[1-354]
------
M
E
N
-
F
P
T
E
Y
F
L
N
T
T
V
-
R
L
L
E
Y
I
R
Y
R
D
--------------
S
N
Y
T
R
E
E
-
R
I
E
N
L
H
Y
A
Y
N
K
A
A
H
H
F
A
Q
P
R
Q
Q
Q
L
L
K
V
D
-
P
K
R
L
Q
A
-
S
----
L
Q
T
I
V
G
M
V
V
Y
S
W
--
A
-
K
V
S
K
E
C
M
A
D
L
S
------
I
H
Y
T
Y
T
L
V
L
D
D
-
S
K
D
D
P
-
Y
P
T
MVN
Y
F
D
D
L
Q
-
A
GREQAH
P
W
W
A
L
V
N
E
-
H
F
P
N
V
L
R
H
-
F
--
G
-
P
F
--
C
S
L
N
L
I
-----
R
S
T
L
---
D
F
F
E
G
C
W
I
E
Q
Y
NFGGFPGSHD
Y
P
Q
F
L
R
R
M
N
GL
G
H
C
V
G
A
S
L
W
P
-
K
E
Q
F
N
E
R
S
L
F
L
E
I
T
S
A
--------
I
A
Q
M
E
N
W
M
V
W
V
-----------------------
N
D
L
M
S
F
Y
K
E
F
D
-
D
E
R
D
Q
I
S
L
V
K
N
Y
V
V
S
D
E
-
I
S
L
H
E
A
L
E
K
L
T
Q
D
T
L
H
-
S
S
K
Q
M
V
A
V
F
SDKD
P
Q
V
M
D
-
T
I
--------
E
C
F
M
H
G
Y
V
T
W
H
L
C
D
R
R
Y
R
L
S
E
I
Y
E
K
V
K
E
E
K
T
E
D
A
Q
-
K
F
C
K
F
Y
E
Q
A
A
N
V
G
A
V
S
-
P
S
E
WAYP
P
V
A
Q
L
-
A
N
V
3
PsiBlast_PDB
76.58
20%
-19
- C9 -
3L8C
-
DLTA_STRP6
A:
[333-506]
-------------------------------------------------------
E
D
G
K
E
L
S
S
G
E
Q
-
G
E
I
----
I
V
T
G
P
A
V
S
-
K
G
Y
L
N
N
-
P
------
E
K
T
A
E
A
F
F
T
F
--
K
G
Q
P
A
Y
H
-----
T
------
G
D
I
G
S
L
T
--
E
D
-
N
I
L
L
Y
G
G
R
L
-----
D
F
Q
I
-
K
--------------------
I
E
L
-
E
--
D
-
V
S
--
Q
Q
L
N
Q
S
-----
P
M
V
A
---
S
A
V
A
V
P
R
Y
N
K
E
------------
H
K
-------
L
L
A
Y
I
V
V
K
D
G
V
K
E
R
F
D
R
E
L
E
L
T
K
A
I
K
A
--------
S
V
K
D
H
M
M
S
Y
M
M
-----------------------
P
S
K
F
L
Y
R
D
S
L
P
L
T
P
N
G
K
I
D
I
K
T
L
I
N
E
V
N
---------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
72.08
20%
-17
- C9 -
3LGX
1
DLTA_STRP1
A:
[338-511]
-------------------------------------------------------
E
D
G
K
E
L
S
S
G
E
Q
-
G
E
I
----
I
V
T
G
P
A
V
S
-
K
G
Y
L
N
N
-
P
------
E
K
T
A
E
A
F
F
T
F
--
K
G
Q
P
A
Y
H
-----
T
------
G
D
I
G
S
L
T
--
E
D
-
N
I
L
L
Y
G
G
R
L
-----
D
F
Q
I
-
K
------------
Y
A
-
G
--
Y
R
I
E
L
-
E
--
D
-
V
S
--
Q
Q
L
N
Q
S
-----
P
M
V
A
---
S
A
V
A
V
P
R
Y
N
K
E
------------
H
K
V
Q
N
----
L
L
A
Y
I
V
V
K
D
G
V
K
E
R
F
D
R
E
L
E
L
T
K
A
I
K
A
--------
S
V
K
D
H
M
M
S
Y
M
M
-----------------------
P
S
K
F
L
Y
R
D
S
L
P
L
T
P
N
G
K
I
D
I
K
T
L
I
N
E
V
N
---------------------------------------------------------------------------------------------------------------------
5
HHSearch
71.46
23%
-32
- C10 -
3JQO
-
?
B:
[4-118]
----------------------------------------------------------------------------
D
K
K
R
I
T
-
Q
K
L
K
Q
T
-
A
----
F
A
G
A
K
N
Y
Q
Y
V
M
S
--
E
-
Q
--
P
E
-----
M
------
R
S
I
Q
P
V
H
V
W
D
N
-
Y
R
F
T
R
-
F
E
F
-----
P
A
----------------
N
A
-
E
L
P
Q
V
Y
M
I
S
A
--
S
-
G
K
--
E
T
L
P
N
S
-----
H
V
V
G
ENR
N
I
I
E
V
E
T
V
A
K
E
------------
W
R
I
R
L
----
G
D
K
V
V
G
V
R
N
N
-
N
F
A
P
G
R
G
A
V
A
T
G
T
A
S
P
--------
D
V
R
R
V
Q
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
Fugue
71.45
12%
45
- C4 -
1SLQ
-
VP4_ROTRH
A:
[253-522]
-----D
I
V
V
-
S
K
T
S
L
W
K
E
M
Q
Y
-
N
R
D
I
---
T
I
R
--------------
F
K
F
A
S
S
I
-
V
K
S
G
G
L
---
G
Y
K
W
S
E
I
----
S
F
K
P
A
N
Y
Q
-
Y
T
Y
T
R
D
-
G
----
E
E
V
T
A
H
T
T
C
S
V
N
G
M
N
-
D
F
N
F
N
-----
G
GSLPT
D
F
V
I
S
R
Y
E
V
I
K
E
-
N
S
Y
V
Y
-
V
D
Y
W
----
D
D
S
Q
-
A
------------
F
R
-
N
M
V
Y
V
R
S
L
-
A
--
A
-
N
L
--
N
S
V
I
C
T
-------
G
G
---
D
Y
S
F
A
L
P
V
G
Q
W
------------
P
V
M
T
G
----
G
A
V
S
L
H
S
A
G
V
-
T
L
S
T
Q
F
T
-------------------
D
F
V
S
L
N
S
L
R
-----------------------
F
R
F
R
L
T
V
E
E
P
S
-
F
S
I
T
R
T
R
V
S
R
L
Y
G
L
P
A
A
-
N
P
N
N
G
K
E
Y
Y
E
V
A
G
R
F
S
-
L
I
S
L
V
P
S
N
D
-----
D
Y
Q
T
-
P
I
--------
T
N
S
V
T
V
--------------------
R
Q
D
L
E
R
Q
L
G
-
E
L
R
E
E
F
N
A
L
S
Q
E
I
A
M
S
-
Q
L
I
----
D
L
A
L
-----
16
Fugue
70.14
25%
-36
- C10 -
2OFQ
1
?
A:
[1-95]
--------------------------------------------------------------------------------------------------
A
G
A
K
N
Y
Q
Y
V
--
M
-
S
E
Q
P
E
-----
M
------
R
S
I
Q
P
V
H
V
W
D
N
-
Y
R
F
T
R
-
F
E
F
-----
P
A
N
A
-----------------
E
L
P
Q
V
Y
M
I
-
S
A-
S
-
G
K
--
E
T
L
P
N
S
-----
H
V
V
G
ENR
N
I
I
E
V
E
T
V
A
K
E
------------
W
R
I
R
L
----
G
D
K
V
V
G
V
R
N
N
-
N
F
A
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
HHSearch
69.46
24%
-49
- C10 -
2N01
-
?
B:
[12-105]
-----------------------------------------------------------------------------------------------
R
R
Y
Y
Y
D
Y
D
Y
A
T
R
--
T
-----
K
-----
K
------
S
W
L
I
P
S
R
V
Y
D
D
-
G
K
F
T
Y
-
I
N
M
-----
D
L
T
R
-
F
P-----------
T
G
-
N
F
P
A
V
F
A
R
-
E
K-
E
H
A
E
--
D
F
L
V
N
T
-----
T
V
E
G
---
N
T
L
I
V
H
G
T
Y
P
F
------------
L
V
V
R
H
----
G
D
N
V
V
G
L
R
R
N
-
K
Q
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
Fugue
68.56
23%
-26
* C10 *
2N01
-
?
B:
[1-106]
-----------------------------------------------------------------------------------
G
S
H
M
N
A
-
K
----
I
L
K
D
R
R
Y
Y
Y
D
Y
D
--
Y
-
A
T
R
T
K
-----
K
------
S
W
L
I
P
S
R
V
Y
D
D
-
G
K
F
T
Y
-
I
N
M
-----
D
L
T
R
-
F
------------
P
T
G
N
F
P
A
V
F
A
R
-
E
KE
H
-
A
E
--
D
F
L
V
N
T
-----
T
V
E
G
---
N
T
L
I
V
H
G
T
Y
P
F
------------
L
V
V
R
H
----
G
D
N
V
V
G
L
R
R
N
-
K
Q
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
60.21
31%
-43
- C10 -
2N01
-
?
B:
[34-106]
---------------------------------------------------------------------------------------------------------------------------------------
V
Y
D
D
-
G
K
F
T
Y
-
I
N
M
-----
D
L
T
R
F
P
------------
T
G
-
N
F
P
A
V
F
A
R
-
E
--
K
-
E
H
AE
D
F
L
V
N
T
-----
T
V
E
G
---
N
T
L
I
V
H
G
T
Y
P
F
------------
L
V
V
R
H
----
G
D
N
V
V
G
L
R
R
N
-
K
Q
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
Fugue
59.00
12%
52
- C7 -
1O9B
4
YDIB_ECOLI
A:
[7-286]
---Y
E
L
I
G
L
M
A
Y
P
I
R
H
S
L
S
P
E
M
Q
N
K
A
---
L
E
K
--------------
A
G
L
P
F
T
Y
M
A
F
E
V
D
N
D
S
F
P
G
A
I
E
G
L
----
K
A
L
----
K
M
R
G
T
G
V
S
M
P
-----
N
K
Q
L
A
C
E
Y
V
D
E
--
L
-
T
P
A
A
K
-----
L
------
V
G
A
I
N
T
I
V
N
D
D
-
G
Y
L
R
G
-
Y
N
T
-----
D
G
T
G
-
H
------------
I
R
-
A
I
K
E
S
G
F
D
-
I
--
K
-
G
-------
K
T
M
----
V
L
L
G
---
A
G
G
A
S
T
A
I
G
A
Q
------------
G
A
I
E
G
----
L
K
E
I
K
L
F
N
R
R
-
D
E
F
F
D
K
A
L
A
F
A
Q
R
V
N
E
--------
N
T
D
C
V
V
T
V
T
D
L
-----------------------
A
D
Q
Q
A
F
A
E
A
L
A
-
S
A
D
I
L
T
N
G
T
K
V
-----
G
M
K
P
L
E
N
E
S
L
V
N
D
I
S
L
L
H
-
P
G
L
L
V
T
E
C
V
-----
Y
N
P
H
M
T
-----------
K
L
L
Q
Q
A
Q
Q
A
---------------
G
C
K
T
I
D
G
Y
G
M
L
L
W
Q
G
A
E
Q
F
T
L
W
T
G
K
D
F
P
L
E
----
Y
V
K
Q
V
M
G
F
-
19
Fugue
58.64
13%
34
- C8 -
1W3B
-
OGT1_HUMAN
B:
[1-388]
GPMELA
H
R
E
-
Y
Q
A
G
D
F
E
A
A
E
R
-
H
C
M
Q
---
L
W
R
QEPDNTGVLLLLSS
I
H
F
Q
C
R
R
-
L
D
R
S
A
H
F
S
T
L
A
I
K
Q
N
P
----
L
L
A
E
A
Y
S
N
-
L
G
N
V
Y
K
-
E
RGQL
Q
E
A
I
E
H
Y
R
H
A
L
R
--
L
-
K
P
D
F
I
-----
D
------
G
Y
I
N
L
A
A
A
L
V
A
A
G
D
M
E
G
-
A
V
Q
-----
A
Y
V
S
-
A
------------
L
Q
-
Y
N
P
D
L
Y
C
V
-
R
--
S
-
D
L
--
G
N
L
L
K
A
LGRLE
E
A
K
A
---
C
Y
L
K
A
I
E
T
Q
P
N
------------
F
A
V
A
W
----
S
N
L
G
C
V
F
N
A
Q
-
G
E
I
W
L
A
I
H
H
F
E
K
A
V
T
L
DPNFLDAY
I
N
L
G
N
V
L
K
E
A
R
IFDRAVAAYLRALSLSPNHAVVH
G
N
L
A
C
V
Y
Y
E
Q
G
-
L
I
D
L
A
I
D
T
Y
R
R
A
I
E
L
Q
P
-
H
F
P
D
A
Y
C
N
L
A
N
A
L
K
E
K
G
S
V
A
E
A
E
D
C
Y
-----
N
T
A
L
-
R
L
CPTHADSY
R
K
A
L
E
V
F
P
E
F
A
A
A
H
S
N
L
A
S
V
L
Q
Q
Q
G
-
K
L
Q
E
A
L
M
H
Y
-
K
E
A
I
R
I
S
P
T
F
A
D
A
Y
S
N
-
M
G
N
----
T
L
K
E
M
-
Q
D
-
2
PsiBlast_PDB
51.18
30%
29
- C9 -
2VE7
-
NUF2_HUMAN (first)
C:
[149-208]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
Y
K
S
S
A
D
K
M
Q
Q
L
N
A
--------
A
H
Q
E
A
L
M
K
L
E
-------------------------------------
I
P
S
A
V
Y
V
A
Q
L
Y
H
Q
V
S
K
-
I
E
W
E
Y
E
C
E
P
G
M
V
K
G
I
H
-
Q
P
I
H
L
D
S
T
Q
-----
L
S
R
K
-
F
I
--------
S
D
Y
L
W
S
L
V
-------------------------------------------------------------
14
HHSearch
40.24
19%
65
* C9 *
1K8K
-
ARPC5_BOVIN
G:
[70-106]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
V
-
K
D
R
A
G
S
I
V
L
K
V
L
I
S
F
K
A
-
N
D
I
E
K
A
V
Q
S
L
D
K
N
G
V
D
-
L
L
M
K
Y
I
Y
K
G
-----
F
E
S
P
-
S
D
--------
N
S
S
A
V
L
L
Q
W
H
E
K
A
L
A
A
G
G
V
G
S
I
V
R
V
-
L
T
A
R
K
T
V
------------------------------------
8
HHSearch
39.85
29%
44
- C9 -
2Q97
1
?
T:
[41-88]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
A
A
L
L
D
E
I
L
R
A
T
Q
N
-
L
D
L
R
K
Y
-
E
N
L
N
T
E
Q
Q
K
-
A
Y
E
Q
V
Q
R
D
L
-----
S
Q
L
S
-
P
E
--------
T
K
A
L
L
I
E
N
Q
R
K
E
K
T
L
L
E
K
A
R
K
L
F
Q
R
--------------------------------------------
10
HHSearch
35.47
27%
-5
- C6 -
3FUY
1
?
A:
[32-57]
--------------------------------------------------------------------------------------------------------------------------------
P
S
L
V
T
I
R
D
F
D
N
-
G
Q
F
A
V
-
L
R
I
-----
G
R
T
------------------
G
F
P
A
D
K
G
D
-
I
--
D
-
L
C
--
L
D
K
M
K
G
-----
V
R
D
A
---
Q
Q
S
I
G
D
D
T
E
F
G
------------
F
K
G
P
H
----
I
R
I
R
C
V
D
I
D
D
-
K
H
T
Y
N
A
M
V
Y
V
D
L
I
V
G
T
--------
G
A
S
E
V
E
R
E
T
A
E
-----------------------
E
L
A
K
E
K
L
R
A
A
L
-
Q
V
D
I
A
D
E
H
S
C
V
T
Q
F
E
M
K
-
L
R
E
E
L
L
S
S
D
S
F
H
P
D
K
D
-
E
Y
Y
K
D
F
L
-------------------------------------------------------------------------------------------
9
HHSearch
28.53
23%
50
- C3 -
3FZ2
1
TTTP_LAMBD
A:
[23-49]
------------------------------------------------------------------------------------------------------------------------------------
G
A
T
F
F
-
D
-
G
R
P
A
V
-
F
D
------
E
A
-------------------
D
F
P
A
V
A
V
Y
L
T
--
G
-
A
E
--
Y
T
G
E
S
D
-----
T
W
Q
A
---
E
L
H
I
E
V
F
L
P
A
Q
------------
V
P
A
S
E
----
L
D
A
W
M
E
S
R
I
Y
-
P
V
M
S
D
I
P
A
L
S
D
L
I
T
S
M
--------
V
A
S
G
Y
D
Y
R
R
D
D
-----------------------
D
A
G
L
W
S
S
A
D
L
T
-
Y
V
I
T
Y
E
M
------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
28.33
45%
506
- C2 -
2JPP
-
?
A:
[8-18]
--------------------------------------------------------
V
G
E
S
I
N
I
G
D
D
I
T
I
T
----
I
L
G
V
S
G
Q
Q
-
V
R
I
G
I
N
-
A
----
P
K
D
V
A
V
H
R
E
E
I
Y
--
Q
-
R
I
Q
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
26.67
38%
118
- C9 -
3DLM
-
A:
[105-120]
-------------------------------------------------------------------------------------------------------------------------------------
L
I
F
F
D
D
-
G
Y
A
S
Y
-
V
T
Q
-----
S
E
L
Y
-
P
------------
I
C
-
R
P
L
K
K
T
W
E
-
D
--
I
-
E
D
--
I
S
C
R
D
F
-----
I
E
E
Y
---
V
T
A
Y
P
N
R
P
M
V
L
------------
L
K
S
G
Q
----
L
I
K
T
E
W
E
G
T
W
-
W
K
S
R
V
E
E
V
D
G
S
L
V
R
I
L
--------
F
L
D
D
K
R
C
E
W
I
Y
-----------------------
R
G
S
T
R
L
E
P
-----------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
21.80
36%
914
- C1 -
1VPZ
-
CSRA_PSEAE
A:
[8-18]
--------------------------------------------------------
V
G
E
T
L
M
V
G
D
D
V
T
V
T
----
V
L
G
V
K
G
N
Q
-
V
R
I
G
V
N
-
A
----
P
K
E
V
A
V
H
R
E
E
I
Y
--
Q
-
R
I
Q
K
E
-----
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
19.17
19%
129
- C9 -
2KJ1
-
?
A:
[77-103]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
M
-----
E
V
L
S
---
D
H
I
V
I
E
G
L
S
A
E
------------
E
I
I
K
M
----
G
E
T
V
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------