@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo0222: (2016-03-13 )
MSDYLVKALAYDGMARVYAAVTTETIKEAQRRHDTWSVSSAALGRTMTGTLFLGAMQKEDQKITVKIEGDGPIGPIVADSNAQGQIRGYVTNPHVHFSELNEAGKLDVRRGVGTSGMLSVVKDLGFGENFTGQTPIVSGEIGEDFTYYLATSEQINSSVGVGVLVNPDDTIEAAGGFMLQLLPGATDEIIDEIEKNLMALPTVSRMIEAGETPESILAKLAGGEDKLQILEKIPVSFECNCSKERFGSAIISLGKEEIRSMIEEDHGAEAECHFCRNTYDFSEEELKTLYEEAK
Atome Classification :
(20 SA)
---------------------------------------------------------------------------------------------------------------------------------------------------------------.........10---........20...-----.....30..----------...-...40.....--...50.......----.60........70.-.......80..--....-..---.90..---------------......100.....-..110.......120.......130.......140-.-----..--------.....150.------......-.160...-....------------------170....-..-----------.180....-..-..190........200----.-.......210----........220.--......230.......-240.......250.......260.......270.......280.-......290..-----------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---------------------------------------------------------------------------------------------------------------------------------------------------------------MS
D
Y
L
V
K
A
L
A
Y---D
G
M
A
R
V
Y
A
A
V
T
T
E
-----
T
I
K
E
A
Q
R
RH----------DTW-SV
S
S
A
ALGRT--
M
T
G
T
L
F
L
GAMQK----ED
Q
K
I
T
V
K
I
EGDGP-IG
P
I
VADS-NA--Q
G
Q
I
-
R
G
---
Y
VTNP---------------
H
V
H
F
S
E
LNEAGK
L
D
-
V
RRGVG
T
S
G
M
L
S
V
V
K
D
LGFGENFTGQTPIVSGEI--G-----E
D
--------
F
T
Y
Y
L
A-
T
S
------
E
QINSS-V
G
V
G
V
L
V-NPDD------------------
T
I
E
AAG
G
-
F
M
-----------
L
Q
-LLPGA-
T
D
-
E
I
I
-
D
E
I
E
K
N
L
M
A
L
P
-----
T
-
V
S
R
M
I
EAG-E----
T
P
E
S
I
L
A
K
LAG
G
--
E
D
K
L
Q
I
L
E
KIP
V
S
F
EC-NC
S
K
E
R
F
G
S
A
I
I
S
L
G
K
E
E
I
R
S
M
I
E
EDHGAE
A
E
C
H
F
CRNTYDF
S
E
-
E
E
L
K
T
L
Y
E
EAK-----------------------------------------------------------------------------------------
8
HHSearch
99.81
64%
-91
- C3 -
1VZY
5
HSLO_BACSU
A:
[1-289]
----------------------------------------------------------------------------------------------------------------------------------------------------------------
M
D
Y
L
V
K
A
L
A
Y
---
D
G
K
V
R
A
Y
A
A
R
T
T
D
-----
M
V
N
E
G
Q
R
R
H
----------
G
T
W
-
P
T
A
S
A
A
L
G
R
T
--
M
T
A
S
L
M
L
G
A
M
L
K
----
G
D
D
K
L
T
V
K
I
E
G
G
G
P
-
I
G
A
I
V
A
D
A
-
N
A
--
K
G
E
V
-
R
A
---
Y
V
S
N
P
---------------
Q
V
H
F
-
D
L
N
A
A
G
K
L
D
-
V
R
R
A
V
G
T
N
G
T
L
S
V
V
K
D
L
G
L
R
E
F
F
T
G
Q
V
E
I
V
S
G
E
L
--
G
-----
D
D
--------
F
T
Y
Y
L
V
-
S
S
------
E
Q
V
P
S
S
-
V
G
V
G
V
L
V
-
N
P
D
N
------------------
T
I
L
A
A
G
G
-
F
I
-----------
I
Q
-
L
M
P
G
T
-
D
D
-
E
T
I
-
T
K
I
E
Q
R
L
S
Q
V
E
-----
P
-
I
S
K
L
I
Q
K
G
-
L
----
T
P
E
E
I
L
E
E
V
L
G
---
E
-
K
P
E
I
L
E
T
M
P
V
R
F
H
C
-
P
C
S
K
E
R
F
E
T
A
I
L
G
L
G
K
K
E
I
Q
D
M
I
E
E
D
G
Q
A
E
A
V
C
H
F
C
N
E
K
Y
L
F
T
K
-
E
E
L
E
G
L
R
D
Q
T
------------------------------------------------------------------------------------------
1
PsiBlast_PDB
98.99
63%
-92
* C3 *
1VZY
5
HSLO_BACSU
A:
[2-288]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
D
Y
L
V
K
A
L
A
Y
---
D
G
K
V
R
A
Y
A
A
R
T
T
D
-----
M
V
N
E
G
Q
R
R
H
----------
G
T
W
-
P
T
A
S
A
A
L
G
R
T
--
M
T
A
S
L
M
L
G
A
M
L
K
----
G
D
D
K
L
T
V
K
I
E
G
G
G
P
-
I
G
A
I
V
A
D
A
-
N
A
--
K
G
E
V
-
R
A
---
Y
V
S
N
P
---------------
Q
V
H
F
-
D
L
N
A
A
G
K
L
D
-
V
R
R
A
V
G
T
N
G
T
L
S
V
V
K
D
L
G
L
R
E
F
F
T
G
Q
V
E
I
V
S
G
E
L
--
G
-----
D
D
--------
F
T
Y
Y
L
V
-
S
S
------
E
Q
V
P
S
S
-
V
G
V
G
V
L
V
-
N
P
D
N
------------------
T
I
L
A
A
G
G
-
F
I
-----------
I
Q
-
L
M
P
G
T
-
D
D
-
E
T
I
-
T
K
I
E
Q
R
L
S
Q
V
E
-----
P
-
I
S
K
L
I
Q
K
G
-
L
----
T
P
E
E
I
L
E
E
V
L
G
----
E
K
P
E
I
L
E
T
M
P
V
R
F
H
C
-
P
C
S
K
E
R
F
E
T
A
I
L
G
L
G
K
K
E
I
Q
D
M
I
E
E
D
G
Q
A
E
A
V
C
H
F
C
N
E
K
Y
L
F
T
K
-
E
E
L
E
G
L
R
D
Q
-------------------------------------------------------------------------------------------
6
PsiBlast_CBE
97.34
63%
-90
- C3 -
1VZY
3
HSLO_BACSU
B:
[2-286]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
D
Y
L
V
K
A
L
A
Y
---
D
G
K
V
R
A
Y
A
A
R
T
T
D
-----
M
V
N
E
G
Q
R
R
H
----------
G
T
W
-
P
T
A
S
A
A
L
G
R
T
--
M
T
A
S
L
M
L
G
A
M
L
K
----
G
D
D
K
L
T
V
K
I
E
G
G
G
P
-
I
G
A
I
V
A
D
A
-
N
A
--
K
G
E
V
-
R
A
---
Y
V
S
N
P
---------------
Q
V
H
F
-
D
L
N
A
A
G
K
L
D
-
V
R
R
A
V
G
T
N
G
T
L
S
V
V
K
D
L
G
L
R
E
F
F
T
G
Q
V
E
I
V
S
G
E
L
--
G
-----
D
D
--------
F
T
Y
Y
L
V
-
S
S
------
E
Q
V
P
S
S
-
V
G
V
G
V
L
V
-
N
P
D
N
------------------
T
I
L
A
A
G
G
-
F
I
-----------
I
Q
-
L
M
P
G
T
-
D
D
-
E
T
I
-
T
K
I
E
Q
R
L
S
Q
V
E
-----
P
-
I
S
K
L
I
Q
K
G
-
L
----
T
P
E
E
I
L
E
E
V
L
G
----
E
K
P
E
I
L
E
T
M
P
V
R
F
H
C
-
P
C
S
K
E
R
F
E
T
A
I
L
G
L
G
K
K
E
I
Q
D
M
I
E
E
D
G
Q
A
E
A
V
C
H
F
C
N
E
K
Y
L
F
T
K
-
E
E
L
E
G
L
R
---------------------------------------------------------------------------------------------
9
HHSearch
85.52
37%
-97
- C3 -
1VQ0
5
HSLO_THEMA
A:
[13-297]
------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
I
Y
Y
G
T
M
F
---
D
H
K
V
R
F
S
I
V
R
M
R
E
-----
V
V
E
E
A
R
N
R
H
----------
A
L
S
-
Y
L
A
T
V
V
L
G
R
A
--
L
I
G
A
A
L
V
T
P
W
L
A
----
E
K
E
R
W
T
L
D
I
E
G
N
G
P
-
I
R
R
V
V
A
Q
S
-
T
S
--
E
F
T
V
-
R
G
---
Y
V
A
N
P
---------------
K
V
E
L
-
P
L
N
E
K
G
K
F
D
-
V
A
G
A
I
G
Q
-
G
V
L
R
V
V
R
D
L
G
L
K
T
P
F
V
S
Q
V
P
L
V
S
G
E
I
--
A
-----
E
D
--------
L
A
Y
Y
F
A
-
V
S
------
E
Q
I
P
S
A
-
F
S
I
G
V
L
V
-
D
S
D
-------------------
G
V
K
I
A
G
G
-
F
A
-----------
V
Q
-
I
I
D
R
T
L
E
Q
-
E
K
V
-
E
M
I
E
K
N
I
K
N
L
P
-----
S
-
I
S
K
L
F
Q
-
E
-
A
----
E
P
L
D
V
L
E
R
I
F
G
---
E
-
K
V
G
F
V
E
T
A
E
I
K
Y
K
C
-
D
C
N
R
E
K
A
K
N
A
L
L
V
L
D
K
K
E
L
E
D
M
R
-
K
E
G
K
G
E
V
V
C
K
W
C
N
T
R
Y
V
F
S
E
-
E
E
L
E
E
L
L
K
F
K
V
-----------------------------------------------------------------------------------------
2
PsiBlast_PDB
82.11
37%
-91
- C3 -
1VQ0
5
HSLO_THEMA
A:
[20-285]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
---
D
H
K
V
R
F
S
I
V
R
M
R
E
-----
V
V
E
E
A
R
N
R
H
----------
A
L
S
-
Y
L
A
T
V
V
L
G
R
A
--
L
I
G
A
A
L
V
T
P
W
L
A
----
E
K
E
R
W
T
L
D
I
E
G
N
G
P
-
I
R
R
V
V
A
Q
S
-
T
S
--
E
F
T
V
-
R
G
---
Y
V
A
N
P
---------------
K
V
E
L
P
-
L
N
E
K
G
K
F
D
-
V
A
G
A
I
G
-
Q
G
V
L
R
V
V
R
D
L
G
L
K
T
P
F
V
S
Q
V
P
L
V
S
G
E
I
--
A
-----
E
D
--------
L
A
Y
Y
F
A
-
V
S
------
E
Q
I
P
S
A
-
F
S
I
G
V
L
V
-
D
-
S
D
------------------
G
V
K
I
A
G
G
-
F
A
-----------
V
Q
-
I
I
D
R
T
-
L
E
Q
E
K
V
-
E
M
I
E
K
N
I
K
N
L
P
-----
S
-
I
S
K
L
F
Q
E
A
-
E
-----
P
L
D
V
L
E
R
I
F
G
----
E
K
V
G
F
V
E
T
A
E
I
K
Y
K
C
-
D
C
N
R
E
K
A
K
N
A
L
L
V
L
D
K
K
E
L
E
D
M
R
K
E
G
K
G
-
E
V
V
C
K
W
C
N
T
R
Y
V
F
S
------------------------------------------------------------------------------------------------------
7
PsiBlast_CBE
81.66
37%
-90
- C3 -
1VQ0
5
HSLO_THEMA
B:
[20-285]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
---
D
H
K
V
R
F
S
I
V
R
M
R
E
-----
V
V
E
E
A
R
N
R
H
----------
A
L
S
-
Y
L
A
T
V
V
L
G
R
A
--
L
I
G
A
A
L
V
T
P
W
L
A
----
E
K
E
R
W
T
L
D
I
E
G
N
G
P
-
I
R
R
V
V
A
Q
S
-
T
S
--
E
F
T
V
-
R
G
---
Y
V
A
N
P
---------------
K
V
E
L
P
-
L
N
E
K
G
K
F
D
-
V
A
G
A
I
G
-
Q
G
V
L
R
V
V
R
D
L
G
L
K
T
P
F
V
S
Q
V
P
L
V
S
G
E
I
--
A
-----
E
D
--------
L
A
Y
Y
F
A
-
V
S
------
E
Q
I
P
S
A
-
F
S
I
G
V
L
V
-
D
-
S
D
------------------
G
V
K
I
A
G
G
-
F
A
-----------
V
Q
-
I
I
D
R
T
-
L
E
Q
E
K
V
-
E
M
I
E
K
N
I
K
N
L
P
-----
S
-
I
S
K
L
F
Q
E
A
-
E
-----
P
L
D
V
L
E
R
I
F
G
----
E
K
V
G
F
V
E
T
A
E
I
K
Y
K
C
-
D
C
N
R
E
K
A
K
N
A
L
L
V
L
D
K
K
E
L
E
D
M
R
K
E
G
K
G
-
E
V
V
C
K
W
C
N
T
R
Y
V
F
S
------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
68.24
24%
-61
- C3 -
3M7M
-
HSLO_ECOLI
X:
[7-232]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
D
Q
L
H
R
Y
L
F
E
---
N
F
A
V
R
G
E
L
V
T
V
S
E
-----
T
L
Q
Q
I
L
E
N
H
----------
D
Y
P
-
Q
P
V
K
N
V
L
A
E
L
--
L
V
A
T
S
L
L
T
A
T
L
K
----
F
D
G
D
I
T
V
Q
L
Q
G
D
G
P
-
M
N
L
A
V
I
N
G
-
N
N
--
N
Q
Q
M
-
R
G
---
V
A
R
V
Q
-------------------
G
E
I
P
E
N
A
--
D
-
L
K
T
L
V
G
-
N
G
Y
V
V
I
T
I
T
P
S
E
G
E
R
Y
Q
G
V
V
G
L
E
G
D
T
L
--
A
-----
A
D
--------
L
E
D
Y
F
M
-
R
S
------
E
E
L
P
T
R
-
L
F
I
R
--
T
-
G
D
V
D
------------------
G
K
P
A
A
G
G
-
M
L
-----------
L
Q
-
V
M
P
A
Q
-
N
A
-
Q
------
Q
D
D
F
D
H
L
A
-----
T
-
L
T
E
T
I
K
T
E
-
E
LLTL
P
A
N
E
V
L
W
R
L
Y
-
H
--
E
E
E
V
T
V
Y
D
P
Q
D
V
E
F
K
C
--------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
64.39
25%
-60
- C3 -
1HW7
6
HSLO_ECOLI
A:
[6-234]
----------------------------------------------------------------------------------------------------------------------------------------------------------------
H
D
Q
L
H
R
Y
L
F
E
---
N
F
A
V
R
G
E
L
V
T
V
S
E
-----
T
L
Q
Q
I
L
E
N
H
----------
D
Y
P
-
Q
P
V
K
N
V
L
A
E
L
--
L
V
A
T
S
L
L
T
A
T
L
K
----
F
D
G
D
I
T
V
Q
L
Q
G
D
G
P
-
M
N
L
A
V
I
N
G
-
N
N
--
N
Q
Q
M
-
R
G
---
V
A
R
V
Q
---------------
G
E
I
P
------
E
N
A
D
-
L
K
T
L
V
G
N
-
G
Y
V
V
I
T
I
T
P
S
E
G
E
R
Y
Q
G
V
V
G
L
E
G
D
T
L
--
A
-----
A
C
--------
L
E
D
Y
F
M
-
R
S
------
E
Q
L
P
T
R
-
L
F
I
R
T
---
G
D
V
D
------------------
G
K
P
A
A
G
G
-
M
L
-----------
L
Q
-
V
M
P
A
Q
-
N
--
A
Q
Q
-
D
D
F
D
H
-
L
A
T
L
T
-----
E
T
I
K
T
E
E
L
L
T
-
L
----
P
A
N
E
V
L
W
R
L
Y
H
---
E
E
E
V
T
V
Y
D
P
Q
D
V
E
F
K
C
-
T
C
-----------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
64.17
25%
-64
- C3 -
1HW7
6
HSLO_ECOLI
A:
[7-234]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
D
Q
L
H
R
Y
L
F
E
---
N
F
A
V
R
G
E
L
V
T
V
S
E
-----
T
L
Q
Q
I
L
E
N
H
----------
D
Y
P
-
Q
P
V
K
N
V
L
A
E
L
--
L
V
A
T
S
L
L
T
A
T
L
K
----
F
D
G
D
I
T
V
Q
L
Q
G
D
G
P
-
M
N
L
A
V
I
N
G
-
N
N
--
N
Q
Q
M
-
R
G
---
V
A
------------------
R
V
Q
-
G
E
I
P
E
N
A
--
D
-
L
K
T
L
V
G
-
N
G
Y
V
V
I
T
I
T
P
S
E
G
E
R
Y
Q
G
V
V
G
L
E
G
D
T
L
--
A
-----
A
C
--------
L
E
D
Y
F
M
-
R
S
------
E
Q
L
P
T
R
-
L
F
I
R
--
T
-
G
D
V
D
------------------
G
K
P
A
A
G
G
-
M
L
-----------
L
Q
-
V
M
P
A
Q
-
N
A
-
Q
------
Q
D
D
F
D
H
L
A
-----
T
-
L
T
E
T
I
K
T
E
-
E
L
L
TL
P
A
N
E
V
L
W
R
L
Y
-
H
--
E
E
E
V
T
V
Y
D
P
Q
D
V
E
F
K
C
-
T
C
-----------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
63.96
26%
-53
- C3 -
1I7F
3
HSLO_ECOLI
A:
[5-231]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
D
Q
L
H
R
Y
L
F
E
---
N
F
A
V
R
G
E
L
V
T
V
S
E
-----
T
L
Q
Q
I
L
E
N
H
----------
D
Y
P
-
Q
P
V
K
N
V
L
A
E
L
--
L
V
A
T
S
L
L
T
A
T
L
K
----
F
D
G
D
I
T
V
Q
L
Q
G
D
G
P
-
M
N
L
A
V
I
N
G
-
N
N
--
N
Q
Q
M
-
R
G
---
V
A
R
V
Q
-------------------
G
E
I
P
E
N
A
--
D
-
L
K
T
L
V
G
-
N
G
Y
V
V
I
T
I
T
P
S
E
G
E
R
Y
Q
G
V
V
G
L
E
G
D
T
L
--
A
-----
A
D
--------
L
E
D
Y
F
M
-
R
S
------
E
Q
L
P
T
R
-
L
F
I
R
T
---
G
D
V
D
------------------
G
K
P
A
A
G
G
-
M
L
-----------
L
Q
-
V
M
P
A
Q
-
N
A
-
Q
------
Q
D
D
F
D
H
L
A
-----
T
-
L
T
E
T
I
K
T
E
-
E
L
L
T
L
P
A
N
E
V
L
W
R
L
Y
H
---
E
E
E
V
T
V
Y
D
P
Q
D
V
E
F
K
C
-
T
------------------------------------------------------------------------------------------------------------------------------------------------
34
Fugue
59.89
22%
-44
- C3 -
1I7F
3
HSLO_ECOLI
A:
[4-231]
----------------------------------------------------------------------------------------------------------------------------------------------------------------
H
D
Q
L
H
R
Y
L
F
E
---
N
F
A
V
R
G
E
L
V
T
V
S
E
-----
T
L
Q
Q
I
L
E
N
H
----------
D
Y
P
-
Q
P
V
K
N
V
L
A
E
L
--
L
V
A
T
S
L
L
T
A
T
L
K
----
F
D
G
D
I
T
V
Q
L
Q
G
D
G
P
M
N
L
A
V
I
N
G
N
-
N
----
N
Q
Q
M
R
G
---
V
A
R
V
Q
---------------
G
------
E
I
P
E
N
A
D
-
L
K
T
L
V
G
-
N
G
Y
V
V
I
T
I
T
P
S
E
G
E
R
Y
Q
G
V
V
G
L
E
G
D
T
L
--
A
-----
A
D
--------
L
E
D
Y
F
-
M
R
S
------
E
Q
L
P
T
R
-
L
F
I
--
R
T
-
G
D
V
D
------------------
G
K
P
A
A
G
G
M
L
L
-----------
Q
V
M
P
A
Q
N
A
-
Q
Q
-
D
D
F
-
D
H
L
A
T
L
T
---
E
-----
T
-
I
K
T
E
E
L
L
T
-
L
----
P
A
N
E
V
L
W
R
L
Y
H
---
E
E
E
V
T
V
Y
D
P
Q
D
V
E
F
K
C
-
T
------------------------------------------------------------------------------------------------------------------------------------------------
39
Fugue
53.32
22%
-40
- C4 -
4A1N
4
EXOG_HUMAN
A:
[19-311]
------------------------------------------------------------------------------------------------------------------------------------------------KAVLEQFGFPLTGT
E
A
R
C
Y
T
N
H
A
L
S
Y
---
D
Q
A
K
R
V
P
R
W
V
L
E
H
I
S
KSK
I
M
G
D
A
D
R
K
H
C
K
F
K
P
DPNIP
P
T
F
-
S
A
F
N
E
D
Y
V
G
S
GW
S
R
G
H
M
A
P
A
G
N
N
K
----
F
S
S
K
A
M
A
E
T
F
Y
L
S
N
-
I
V
P
Q
D
F
D
N
-
N
S
--------
G
---
Y
W
N
R
I
---------------
E
M
Y
C
R
E
L
T
E
R
F
E
-
D
-
V
W
V
V
S
G
P
L
T
L
P
Q
T
R
G
D
--------
G
K
K
I
V
S
Y
Q
V
I
--
G
-----
E
D
NVAVPS
H
L
Y
K
V
I
L
A
-
R
R
------
S
S
V
S
T
E
P
L
A
L
G
A
F
V
-
V
P
N
E
------------------
A
I
----
G
-
F
Q
-----------
P
Q
------------
L
-
T
E
F
Q
V
S
L
Q
D
L
E
-----
K
-
L
S
G
L
V
F
F
P
-
H
----
L
D
R
T
S
D
I
R
N
I
C
S
--
V
D
T
C
K
L
L
D
--
F
Q
E
F
T
L
-
Y
L
S
T
R
K
I
E
G
S
V
--
L
R
L
E
K
I
M
V
N
L
K
N
E
I
E
--------------
P
D
-
D
Y
F
M
S
R
Y
E
K
K
L
-----------------------------------------------------------------------------------------
40
Fugue
44.43
18%
-41
- C1 -
1QM4
9
METK1_RAT
A:
[17-396]
------------------------------------------------------------------------------------------------------------------------------------------G
A
F
M
F
T
S
E
S
V
G
EGH
P
D
K
I
C
D
Q
I
S
D
A
V
L
D
A
H
L
K
Q
DP
N
A
K
V
A
C
E
T
V
C
K
T
G
-----
M
V
L
L
C
G
E
I
T
----------
S
M
A
-
M
I
D
Y
Q
R
V
V
R
D
--
T
I
K
H
I
G
Y
D
D
S
A
K
GFDF
K
T
C
N
V
L
V
A
L
E
Q
Q
S
P
------
E
D
V
-
G
A
G
D
Q
G
L
M
-
F
G
---
Y
A
T
D
E
TEECMP
L
T
I
V
L
A
H
K
L
N
T
R
M
A
D
L
R
R
S
G
V
L
P
W
L
R
P
D
S
K
T
Q
V
T
V
Q
Y
V
Q
D
N
G
A
V
I
P
V
R
V
H
T
I
V
I
S
V
Q
H
--
N
EDIT
L
E
A
--------
M
R
E
A
L
K
-
E
Q
VIKAVV
P
A
K
Y
L
D
-
E
D
T
I
Y
H
L
-
Q
P
S
G
RFVIGGPQGD
A
G
V
T
GRKI
I
V
D
T
Y
G
G
-
W
G
AHG
G
G
A
F
S
GKD
Y
T
-
K
V
D
R
S
-
A
A
-
Y
A
A
-
R
W
V
A
K
S
L
V
K
A
G
LCR
R
V
L
-
V
Q
V
S
Y
A
I
G
V
A
----
E
P
L
S
I
S
I
F
T
Y
G
T
SK
K
T
E
R
E
L
L
E
V
V
N
K
N
F
D
L
------
R
P
G
V
I
V
R
D
L
D
L
K
K
P
I
Y
Q
K
T
A
C
Y
G
-----
H
F
G
R
S
E
F
P
W
E
V
P
K
K
L
V
F
-----------------------------------------------------------------------------------------------
38
Fugue
41.15
20%
-8
- C2 -
4NNB
2
?
A:
[4-527]
T
S
L
Y
I
T
A
A
P
I
GA
V
P
K
F
L
DPFEATFIP
S
F
L
L
E
GFFD
A
D
R
C
A
S
I
A
A
D
L
K
T
D
G
W
E
V
V
P
A
G
G
R
L
L
Q
V
GHAQPIAHFP
K
P
W
L
A
A
L
S
N
K
L
A
R
R
I
V
L
Q
L
T
T
Y
G
W
I
V
S
EQG
D
L
L
W
EHE
R
Q
H
H
Y
L
P
P
A
L
I
E
A
I
E
K
E
S
P
A
L
L
K
N
M
E
E
A
GW
I
A
C
A
A
GYWQAGKARSPYLP
I
T
P
E
A
I
T
E
E
T
I
---
R
S
M
R
A
G
A
A
V
V
H
L
H
-----
T
R
D
L
S
D
R
R
R
----------
I
E
I
-
P
----
G
L
G
V
V
--
T
V
G
S
--------------
Q
R
N
Q
I
V
L
D
D
Y
D
A
-
I
V
P
M
V
K
K
R
-
E
P
--
A
A
---------
I
L
N
L
---------------
S
T
S
V
R
G
D
R
H
G
A
R
S
K
-
L
R
R
A
-----------
H
L
K
F
Y
D
D
-
V
G
S
A
P
E
V
A
S
L
S
--
P
-----
A
A
--------
V
V
F
Q
-------------------
G
G
G
G
Y
D
-
N
A
P
D
------------------
F
L
D
A
Q
F
D
-
H
F
-----------
E
R
-
V
G
T
R
P
-
E
V
-
E
V
F
N
H
A
I
V
D
N
A
T
S
L
Y
-------
R
D
R
L
L
R
T
G
-
K
-------
P
V
L
F
M
L
V
A
G
--
V
D
---
Q
Y
R
R
D
P
I
T
------
G
E
V
E
D
D
S
L
I
A
R
V
V
R
E
E
I
S
S
L
L
A
D
E
S
---
A
D
S
H
--
R
R
A
V
E
L
A
I
-
G
Q
L
R
P
V
V
E
R
L
R
A
S
F
PV
S
K
I
S
I
L
L
P
GPMQNLL
V
D
V
A
L
G
L
GLD
G
I
R
V
G
LEDGL
T
V
N
D
ARVPGG
V
R
K
A
RG
T
W
E
Q
V
S
L
V
R
E
E
L
L
G
R
G
A
T
I
L
T
A
A
Q
V
R
D
M
F
GLGI
41
Fugue
37.30
14%
-15
- C4 -
1AGJ
-
ETA_STAAU
A:
[1-242]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
V
S
A
E
-----
E
I
K
K
H
E
E
K
W
----------
N
K
Y
Y
G
V
N
A
F
N
L
P
K
E
--
L
F
S
K
V
D
E
K
D
R
Q
K
----
Y
P
Y
N
T
I
G
N
V
F
V
K
G
Q
--------
T
-
S
A
--
T
G
V
L
-
I
G
KN
T
V
L
T
N
R
---------------
H
I
A
K
F
A
N
G
D
P
S
K
V
S
-
F
R
P
S
I
N
T
D
D
N
G
N
T
E
T
P
Y
G
-------------------------
E
--------
Y
E
V
K
E
I
-
L
Q
------
E
P
F
G
A
G
-
V
D
L
A
L
I
R
L
K
P
D
Q
------------------
N
G
V
S
L
G
D
-
K
I
-----------
S
P
-
A
K
I
G
T
-
S
N
-
D
L
K
-
D
G
D
K
L
E
L
I
G
Y
P
-----
F
-
D
H
K
V
N
Q
M
H
-
R
----
S
E
I
E
L
T
T
L
S
R
G
--------------
L
R
Y
Y
G
-
F
T
V
P
G
N
S
G
S
G
I
F
N
S
N
G
E
L
V
G
I
H
S
S
K
V
S
H
L
D
R
E
H
Q
I
N
Y
G
V
G
-
I
G
N
-
Y
V
K
R
I
I
N
E
K
N
E
-----------------------------------------------------------------------------------------
42
Fugue
36.20
20%
1
* C4 *
2R2C
-
?
A:
[36-180]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
S
Y
----------
K
T
W
-
D
V
P
I
A
--------
K
I
N
I
F
A
V
A
E
Y
T
----
D
T
Q
K
I
K
V
T
V
K
G
K
I
L
-
E
G
N
T
L
P
K
S
M
V
-----
Q
V
-
Y
L
---
L
E
D
K
N
---------------
H
V
L
R
G
A
V
N
G
I
W
G
E
E
-
F
V
N
L
K
D
Y
L
Y
T
Y
A
V
E
P
L
S
G
M
--
S
F
V
A
E
N
Y
S
I
V
A
F
V
Y
D
V
-----
Q
T
--------
F
E
V
Y
D
V
-
V
H
------
V
K
I
N
P
Q
-
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
HHSearch
33.00
12%
43
- C3 -
3NA7
1
?
A:
[206-237]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
R
L
N
D
K
I
Y
T
E
V
L
T
S
-
G
D
M
-
I
T
C
P
Y
C
G
R
I
L
Y
A
E
G
-
A
---------------------------------------------------------------------------------------------------
14
HHSearch
30.95
18%
45
- C3 -
1VQ8
-
RL37A_HALMA
Z:
[20-64]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
E
S
E
M
N
E
D
H
A
C
P
N
C
G
E
D
R
V
D
R
----------------
Q
G
T
G
I
W
Q
C
S
Y
C
D
Y
K
F
T
G
G
S
-
Y
K
P
E
T
-----------------------------------------------------------------------------------------------
37
Fugue
25.75
14%
99
- C3 -
3HE5
-
?
A:
[0-46]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
N
L
V
A
Q
L
E
N
E
V
A
S
L
E
N
E
N
E
T
L
K
K
K
N
L
H
K
K
D
L
I
A
Y
L
E
-
K
E
I
A
N
L
R
K
K
I
E
-----------------------------------------------------------------------------------------
36
Fugue
22.42
32%
131
- C3 -
2KDR
-
?
X:
[1-28]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
---
D
A
A
A
R
V
T
A
I
L
S
S
L
-----
T
V
T
Q
L
L
R
R
L
----------
H
Q
W
-
I
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------