@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo0529: (2016-03-16 )
MVVADYLALFAVICIWGLLLINIVLIVAGYVYYLKNEARKVPEIPVEVPFVSVMVPAHNEGKVIVKTVESLLAFDYPVDRYEIIVINDNSSDNSAELLAAIQAKNPTRFLKIINTDNITGGKGKSNALNIGFAESRGELVAIYDADNTPERQALRILVGEITNDAKLGAVIGKFRTRNRNASWLTRFINIETLSFQWMAQAGRWALFKLCTIPGTNFIVRRSLLEEIGGWDVKAVAEDTEISFRIYMMGYRIKFQAKAVTWEQEPQTLPVWFKQRSRWAKGNIYVILKNVPLLFKREGRRVRFDILYFLSIYFLLLTSLIVSDVLLVLYALGLVHTTLAGLSGALWLLAILLFVAGTFITLTTEKGEISFSNLLFIMLMYVTYCQLWMVVAAYGFFIFLKDTVLKRETKWYKTERF
Atome Classification :
(20 SA)
------------------------------------------------------------------------------------.........10.......-.20........30.....-------------...40........50........60.-.-.......70........80........90-.-.-----.-.-----....100....-----...110...----....120.......130.......140.......-150.......160.......170......-----.180.....-----..-190----------------.-----.-----.-------..-------.---------..200-------.-...------------..-----------.210.------------------......220.......230.---.---.---.---...240....-...--------250.------------------..----....-.260.......270-.......280.......290---........300-----.---......------310......---------.320...-----....330-----.......340.......350.......360.......370.....-----------.-----.380..------.....390....----------------.-------------------..400.......410....----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
------------------------------------------------------------------------------------M
V
V
A
D
Y
L
A
L
F
A
V
I
C
I
W
G
L
-
L
L
I
N
I
V
L
I
V
A
G
Y
V
Y
Y
L
KN-------------
E
A
RKVPEIPVEV
P
F
V
S
V
M
VPAHNE-
G
-
K
-
V
I
V
K
T
V
E
S
L
L
AFDYPV
D
R
Y
E
I
I
V
I
NDNSS-D-
N
-----
S
-
A
-----
E
L
L
A
A
I
QAKNP-----
T
R
F
L
K
I
I
NT----DNITGGKGKSN
A
L
N
I
G
FAESRG
E
L
V
A
I
Y
DADNT
P
-
E
R
Q
A
L
R
I
L
V
G
EITND
A
K
L
G
A
V
I
G
K
F
RTRN-----R
N
A
S
W
L
T
R
F
-----
I
N
-
I
E
-----------------T-----
L
-----
S
-------
F
Q
-------
W
---------
M
A
QAG-------
R
-
W
A
L
------------
F
K
-----------
L
C
TIP------------------G
T
N
F
I
V
R
R
S
L
L
E
E
IGGW
D
V
K
---
A
---V---A---EDT
E
I
S
F
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I
Y
-
M
M
G
--------
Y
R
-
I
------------------
K
F
----
Q
A
K
A
-
V
T
WEQEPQT
L
P
V
W
F
-
K
QRSRWAKG
N
I
Y
V
I
LKNV
P
----
L
L
F
KREG
R
R
V
R
-----
F
---
D
I
L
Y
F
L
------
S
I
Y
F
L
L
L
T
S
---------
L
I
V
S
D
V
L
-----
L
V
L
Y
A
L
G
-----
L
V
H
T
T
L
A
G
L
S
G
A
L
W
L
L
A
I
L
L
F
VAG
T
F
I
T
L
T
TEKGE
I
S
F
S
N
L
L
F
I
M
-----------
L
-----
M
Y
V
T
Y
C
------
Q
L
W
M
V
V
A
A
Y
G
F
F
----------------
I
-------------------
F
L
K
D
T
V
L
KRET
K
W
YKTERF----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
Fugue
84.12
20%
-89
- C2 -
4HG6
4
?
A:
[13-759]
V
V
P
V
L
L
F
L
L
W
V
A
L
L
V
P
F
G
L
L
A
A
A
P
V
A
P
S
A
Q
G
L
I
A
L
S
A
V
V
L
V
A
L
L
K
PFADK
M
V
P
R
F
L
L
L
S
A
A
S
M
L
V
M
R
Y
W
F
W
R
L
F
ETLPPPALD
A
S
F
L
F
A
L
L
L
F
A
V
E
T
F
S
I
S
I
-
F
F
L
N
G
F
L
-----
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D
P
T
D
-------------
R
P
F
P
R
P
L
Q
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N
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D
D
G
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-
Q
-----
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-
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MSPD
P
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----
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PD
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-----
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N
-----------------
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---------
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R
W
G
G
------------
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F
-----------
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---------------------
G
S
A
A
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L
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R
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---
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--------
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K
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L
Y
----
I
D
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A
-
M
I
A
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L
Q
P
E
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F
I
-
Q
Q
R
G
R
W
A
T
G
M
M
Q
M
L
L
L
K
N
P
----
L
F
R
R
G
L
G
I
A
Q
R
-----
L
---
C
Y
L
N
S
M
------
S
F
W
F
F
P
L
V
R
---------
M
M
F
L
V
A
P
-----
L
I
Y
L
F
F
G
--------
I
E
I
F
V
A
T
F
E
E
V
L
A
Y
M
P
G
Y
L
A
V
S
F
L
V
Q
N
A
L
F
A
R
Q
R
W
P
---
L
V
S
-----------
E
-----
V
Y
E
V
A
Q
------
A
P
Y
L
A
R
A
I
V
T
T
L
----------------
L
-------------------
R
P
R
S
A
R
F
A
V
T
A
K
D
E
T
L
S
E
N
YISPIY
R
P
L
L
F
T
F
L
L
C
L
S
G
V
L
A
T
L
V
R
W
V
A
F
PGD
R
S
V
L
L
V
V
G
G
W
A
V
L
N
V
L
L
V
G
F
A
L
R
AVAEKQQRRA
A
P
R
V
Q
M
E
V
P
A
E
A
Q
I
PAFGNRS
L
T
A
T
V
L
D
ASTS
G
V
R
L
L
V
R
L
PGVGDPHPALEAG
G
L
I
Q
F
Q
P
KFPDAPQLE
R
M
V
R
G
R
I
R
S
A
R
R
E
GG
T
V
M
V
G
V
I
F
EAGQP
I
A
V
R
E
T
V
A
Y
L
I
FGES
A
H
W
R
T
M
R
E
A
T
MRPIG
L
L
H
G
M
A
R
I
L
W
M
A
A
A
S
L
P
K
T
A
R
D
F
M
D
E
P
A
R
R
R
R
R
H
E
EPKEKQAHLLAFGTDF
2
PsiBlast_PDB
74.83
25%
-69
- C2 -
4P00
3
?
A:
[134-426]
-------------------------------------------------------------------------------------------------------------------------------------------
P
L
Q
P
E
E
L
P
T
V
D
I
L
V
P
S
Y
N
E
P
A
-
D
-
M
L
S
V
T
L
A
A
A
K
N
M
I
Y
P
A
R
L
R
T
V
V
L
C
D
D
G
G
T
-
D
-
Q
R
C
M
SP
D
-
P
-----
E
L
A
Q
K
A
Q
E
R
R
R
E
L
Q
Q
L
C
R
E
L
G
V
V
Y
S
----
T
R
E
R
N
E
H
A
K
A
G
N
M
S
A
A
L
E
R
L
K
G
E
L
V
V
V
F
D
A
D
H
V
P
-
S
R
D
F
L
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V
G
Y
F
V
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D
P
D
L
F
L
V
Q
T
P
H
F
F
I
N
PD
P
I
Q
R
N
L
A
L
G
D
R
------
C
P
-
P
E
-----------------
N
-----
E
-----
M
-------
F
Y
-------
G
---------
K
I
H
R
G
L
D
-----
R
-
W
G
G
------------
A
F
-----------
F
C
---------------------
G
S
A
A
V
L
R
R
R
A
L
D
E
A
G
G
F
A
G
E
---
T
---
I
---
T
---
E
D
A
E
T
A
L
E
I
H
-
S
R
G
--------
W
K
-
S
------------------
L
Y
----
I
D
R
A
-
M
I
A
G
L
Q
P
E
T
F
A
S
F
I
-
Q
Q
R
G
R
W
A
T
G
M
M
Q
M
L
L
L
K
N
P
----
L
F
R
R
G
L
G
I
A
Q
R
-----
L
---
C
Y
L
N
S
M
------
S
F
W
F
F
P
L
V
R
---------
M
M
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
74.54
25%
-66
- C2 -
4P02
-
?
A:
[134-426]
-------------------------------------------------------------------------------------------------------------------------------------------
P
L
Q
P
E
E
L
P
T
V
D
I
L
V
P
S
Y
N
E
P
A
-
D
-
M
L
S
V
T
L
A
A
A
K
N
M
I
Y
P
A
R
L
R
T
V
V
L
C
D
D
G
G
T
-
D
-
Q
R
C
M
SP
D
-
P
-----
E
L
A
Q
K
A
Q
E
R
R
R
E
L
Q
Q
L
C
R
E
L
G
V
V
Y
S
----
T
R
E
R
N
E
H
A
K
A
G
N
M
S
A
A
L
E
R
L
K
G
E
L
V
V
V
F
D
A
D
H
V
P
-
S
R
D
F
L
A
R
T
V
G
Y
F
V
E
D
P
D
L
F
L
V
Q
T
P
H
F
F
I
N
PD
P
I
Q
R
N
L
A
L
G
D
R
------
C
P
-
P
E
-----------------
N
-----
E
-----
M
-------
F
Y
-------
G
---------
K
I
H
R
G
L
D
-----
R
-
W
G
G
------------
A
F
-----------
F
C
---------------------
G
S
A
A
V
L
R
R
R
A
L
D
E
A
G
G
F
A
G
E
---
T
---
I
---
T
---
E
D
A
E
T
A
L
E
I
H
-
S
R
G
--------
W
K
-
S
------------------
L
Y
----
I
D
R
A
-
M
I
A
G
L
Q
P
E
T
F
A
S
F
I
-
Q
Q
R
G
R
W
A
T
G
M
M
Q
M
L
L
L
K
N
P
----
L
F
R
R
G
L
G
I
A
Q
R
-----
L
---
C
Y
L
N
S
M
------
S
F
W
F
F
P
L
V
R
---------
M
M
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
Fugue
72.76
18%
-73
- C2 -
1XHB
4
GALT1_MOUSE
A:
[8-466]
----------------------------------------------------------------------------------------------------------------
N
R
S
L
P
D
V
R
L
-------------
E
G
C
K
T
K
V
Y
P
D
N
L
P
T
T
S
V
V
I
V
F
H
N
E
A
W
-
S
-
T
L
L
R
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H
S
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S
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M
I
E
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I
V
L
V
D
D
A
S
E
-
R
-
D
-----
F
-
L
-----
K
R
P
L
E
S
Y
V
K
K
L
-----
K
V
P
V
H
V
I
R
M
----
E
Q
---
R
S
G
L
I
R
A
R
L
K
G
A
A
V
S
R
G
Q
V
I
T
F
L
D
A
H
C
E
C
-
T
A
G
W
L
E
P
L
L
A
R
I
K
H
D
R
R
T
V
V
C
P
I
I
D
V
I
S
D
-----
D
T
F
E
Y
M
A
G
S
-----
D
M
-
T
Y
-----------------
G
-----
G
F
N
WKL
N
-------
F
R
-------
W
---------
Y
P
V
P
Q
-------
R
-
E
M
D
R
R
KGDRTLP---
V
R
-----------
T
P
T
M
A
------------------
G
G
L
F
S
I
D
R
D
Y
F
Q
E
I
G
T
Y
D
A
G
---
M
---
D
---
I
WGG
E
N
L
E
I
S
F
R
I
W
-
Q
C
G
G
T
L
E
IVTC
S
H
-
V
------------------
G
H
----
V
F
G
Q
-
I
I
N
K
N
N
R
R
L
A
E
V
W
M
-
D
E
F
K
N
F
F
Y
I
I
S
P
G
V
T
K
V
D
Y
G---
D
I
S
S
R
L
G
L
R
R
K
L
QCKP
F
---
S
W
Y
L
E
N
------
I
Y
P
D
S
Q
I
P
R
---------
H
Y
F
S
L
G
E
-----
I
R
N
V
E
T
N
-----
Q
C
L
D
N
M
A
R
K
E
N
E
K
V
G
I
F
N
C
H
G
M
G
G
N
Q
V
F
S
Y
T
A
N
K
E
I
R
T
D
D
L
C
L
D
V
-----------
S
K
LN
G
P
V
T
M
L
K
C
HHLKGN
Q
L
W
E
Y
D
P
V
K
L
T
L
----------------
Q
HVNSN
Q
C
L
D
K
A
TEEDSQ
V
P
S
I
R
D
C
T
G
S
R
S
Q
Q
W
L
L
R
N
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
70.63
25%
-56
- C2 -
4HG6
2
?
A:
[133-425]
-------------------------------------------------------------------------------------------------------------------------------------------
P
L
Q
P
E
E
L
P
T
V
D
I
L
V
P
S
Y
N
E
P
A
-
D
-
M
L
S
V
T
L
A
A
A
K
N
M
I
Y
P
A
R
L
R
T
V
V
L
C
D
D
G
G
T
-
D
-
Q
R
C
MSP
D
-
P
-----
E
L
A
Q
K
A
Q
E
R
R
R
E
L
Q
Q
L
C
R
E
L
G
V
V
Y
S
----
T
R
E
R
N
E
H
A
K
A
G
N
M
S
A
A
L
E
R
L
K
G
E
L
V
V
V
F
D
A
D
H
V
P
-
S
R
D
F
L
A
R
T
V
G
Y
F
V
E
D
P
D
L
F
L
V
Q
T
P
H
F
F
I
N
PD
P
I
Q
R
N
L
A
L
G
D
R
------
C
P
-
P
E
-----------------
N
-----
E
-----
M
-------
F
Y
-------
G
---------
K
I
H
R
G
L
D
-----
R
-
W
G
G
------------
A
F
-----------
F
C
---------------------
G
S
A
A
V
L
R
R
R
A
L
D
E
A
G
G
F
A
G
E
---
T
---
I
---
T
---
E
D
A
E
T
A
L
E
I
H
-
S
R
G
--------
W
K
-
S
------------------
L
Y
----
I
D
R
A
-
M
I
A
G
L
Q
P
E
T
F
A
S
F
I
-
Q
Q
R
G
R
W
A
T
G
M
M
Q
M
L
L
L
K
N
P
----
L
F
R
R
G
L
G
I
A
Q
R
-----
L
---
C
Y
L
N
S
M
------
S
F
W
F
F
P
L
V
R
---------
M
M
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
Fugue
70.21
16%
-85
- C2 -
2D7I
6
GLT10_HUMAN
A:
[35-570]
--------------------------------------------------------GQKLKDWHD
K
E
A
I
R
R
D
A
Q
RVGNGEQGRP
Y
P
M
T
D
A
E
R
V
D
Q
A
Y
R
E
N
G
F
N
I
Y
V
S
D
K
I
S
L
N
R
S
L
P
D
I
R
H
-------------
P
N
C
N
S
K
R
Y
L
E
T
L
P
N
T
S
I
I
I
P
F
H
N
E
G
W
-
S
-
S
L
L
R
T
V
H
S
V
L
N
R
S
P
P
E
L
V
A
E
I
V
L
V
D
D
F
S
D
-
R
-
E
-----
H
-
L
-----
K
K
P
L
E
D
Y
M
A
L
F
-----
P
S
V
R
I
L
R
T
K
----
K
R
----
E
G
L
I
R
T
R
M
L
G
A
S
V
A
T
G
D
V
I
T
F
L
D
S
H
C
E
A
-
N
V
N
W
L
P
P
L
L
D
R
I
A
R
N
R
K
T
I
V
C
P
M
I
D
V
I
D
H
-----
D
D
F
R
Y
E
T
Q
A
-----
G
D
-
A
M
-----------------
R
-----
G
-----
A
-------
F
D
-------
W
---------
E
M
Y
Y
K
-------
R
-
I
P
I
PPELQKADPS
D
P
F
E
-----------
S
P
V
M
A
------------------
G
G
L
F
A
V
D
R
K
W
F
W
E
L
G
G
Y
D
P
G
---
L
---
E
---
I
WGG
E
Q
Y
E
I
S
F
K
V
W
-
M
C
G
--------
G
R
-
M
E
D
I
PC
S
R
V
G
H
I
Y
R
KYVP
Y
K
V
----
P
A
G
V
-
S
L
A
R
N
L
K
R
V
A
E
V
W
M
D
E
Y
A
E
Y
I
Y
Q
R
R
P
E
Y
R
H
L
S
A
G
----
D
V
A
V
Q
K
K
L
R
S
S
-----
L
NCK
S
F
K
W
F
M
------
T
K
I
A
W
D
L
P
K
FYPPVEPPA
A
A
W
G
E
I
R
N
VGTG
L
C
A
D
T
K
H
-----
G
A
L
G
S
P
L
R
L
E
G
C
V
R
G
R
G
E
A
A
W
N
N
M
Q
V
F
T
F
T
-
W
R
E
D
I
R
P
G
D
P
Q
H
T
K
KFCFDAISHT
S
P
-----
V
T
L
Y
D
C
HSMKGN
Q
L
W
K
Y
R
K
D
K
T
L
Y
HPVSG
S
C
M
D
C
S
ESD
H
R
I
-------------------
F
M
N
T
C
N
P
S
S
L
T
Q
Q
W
L
F
E
H
T
N
S
T
V
L
E
KFNRN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
66.41
22%
-61
- C2 -
5AJN
13
GALT2_HUMAN
A:
[133-370]
-----------------------------------------------------------------------------------------------------------------------------------------------
V
D
L
P
A
T
S
V
V
I
T
F
H
N
E
-
A
-
R
S
A
L
L
R
T
V
V
S
V
L
K
K
S
P
P
H
L
I
K
E
I
I
L
V
D
D
Y
S
N
-
D
P
E
-----
D
-
G
-----
A
L
L
G
K
I
E
K
-----------
V
R
V
L
R
N
----
D
R
R
---
E
G
L
M
R
S
R
V
R
G
A
D
A
A
Q
A
K
V
L
T
F
L
D
S
H
C
E
C
-
N
E
H
W
L
E
P
L
L
E
R
V
A
E
D
------------
R
T
-----
R
V
V
S
P
I
I
D
V
-----
I
N
-
M
D
NF
Q
Y
V
G
A
SAD
L
K
G
G
F
D
W
N
-----
L
-----
V
-------
F
K
-------
W
D
Y
M
T
P
E
Q
R
R
S
R
Q
G
N
-------
P
-
V
A
P
------------
I
K
-----------
T
P
M
I
A
------------------
G
G
L
F
V
M
D
K
F
Y
F
E
E
L
G
K
Y
D
M
M
---
M
---
D
VWG
G
---
E
N
L
E
I
S
F
R
V
W
-
Q
C
G
--------
G
S
-
L
------------------
E
I
I
PC
S
R
V
G
H
-
V
F
R
K
Q
H
P
Y
T
F
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
66.02
22%
-61
- C2 -
4D0Z
11
GALT2_HUMAN
A:
[133-370]
-----------------------------------------------------------------------------------------------------------------------------------------------
V
D
L
P
A
T
S
V
V
I
T
F
H
N
E
-
A
-
R
S
A
L
L
R
T
V
V
S
V
L
K
K
S
P
P
H
L
I
K
E
I
I
L
V
D
D
Y
S
N
-
D
P
E
-----
D
-
G
-----
A
L
L
G
K
I
E
K
-----------
V
R
V
L
R
N
----
D
R
R
---
E
G
L
M
R
S
R
V
R
G
A
D
A
A
Q
A
K
V
L
T
F
L
D
S
H
C
E
C
-
N
E
H
W
L
E
P
L
L
E
R
V
A
E
D
------------
R
T
-----
R
V
V
S
P
I
I
D
V
-----
I
N
-
M
D
NF
Q
Y
V
G
A
S
ADLKGGFDW
N
-----
L
-----
V
-------
F
K
-------
W
D
Y
M
T
P
E
Q
R
R
S
R
Q
G
N
-------
P
-
V
A
P
------------
I
K
-----------
T
P
M
I
A
------------------
G
G
L
F
V
M
D
K
F
Y
F
E
E
L
G
K
Y
D
M
M
---
M
---
D
VWG
G
---
E
N
L
E
I
S
F
R
V
W
-
Q
C
G
--------
G
S
-
L
------------------
E
I
I
PC
S
R
V
G
H
-
V
F
R
K
Q
H
P
Y
T
F
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
65.90
22%
-63
- C2 -
4D0T
4
GALT2_HUMAN
A:
[133-370]
-----------------------------------------------------------------------------------------------------------------------------------------------
V
D
L
P
A
T
S
V
V
I
T
F
H
N
E
-
A
-
R
S
A
L
L
R
T
V
V
S
V
L
K
K
S
P
P
H
L
I
K
E
I
I
L
V
D
D
Y
S
N
-
D
P
E
-----
D
-
G
-----
A
L
L
G
K
I
E
K
-----------
V
R
V
L
R
N
----
D
R
R
---
E
G
L
M
R
S
R
V
R
G
A
D
A
A
Q
A
K
V
L
T
F
L
D
S
H
C
E
C
-
N
E
H
W
L
E
P
L
L
E
R
V
A
E
D
------------
R
T
-----
R
V
V
S
P
I
I
D
V
-----
I
N
-
M
D
NF
Q
Y
V
G
A
S
AD
L
K
G
G
F
D
W
N
-----
L
-----
V
-------
F
K
-------
W
D
Y
MT
P
E
Q
R
R
S
R
Q
G
N
-------
P
-
V
A
P
------------
I
K
-----------
T
P
M
I
A
------------------
G
G
L
F
V
M
D
K
F
Y
F
E
E
L
G
K
Y
D
M
M
---
M
---
D
VWG
G
---
E
N
L
E
I
S
F
R
V
W
-
Q
C
G
--------
G
S
-
L
------------------
E
I
I
PC
S
R
V
G
H
-
V
F
R
K
Q
H
P
Y
T
F
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
65.22
22%
-65
- C2 -
5AJP
11
GALT2_HUMAN
A:
[133-370]
-----------------------------------------------------------------------------------------------------------------------------------------------
V
D
L
P
A
T
S
V
V
I
T
F
H
N
E
-
A
-
R
S
A
L
L
R
T
V
V
S
V
L
K
K
S
P
P
H
L
I
K
E
I
I
L
V
D
D
Y
S
N
-
D
P
E
-----
D
-
G
-----
A
L
L
G
K
I
E
K
-----------
V
R
V
L
R
N
----
D
R
R
---
E
G
L
M
R
S
R
V
R
G
A
D
A
A
Q
A
K
V
L
T
F
L
D
S
H
C
E
C
-
N
E
H
W
L
E
P
L
L
E
R
V
A
E
D
------------
R
T
-----
R
V
V
S
P
I
I
D
V
-----
I
N
-
M
D
NF
Q
Y
V
G
A
S
AD
L
K
G
G
F
D
W
N
-----
L
-----
V
-------
F
K
-------
W
D
Y
M
T
P
E
Q
R
R
S
R
Q
G
N
-------
P
-
V
A
P
------------
I
K
-----------
T
P
M
I
A
------------------
G
G
L
F
V
M
D
K
F
Y
F
E
E
L
G
K
Y
D
M
M
---
M
---
D
VWG
G
---
E
N
L
E
I
S
F
R
V
W
-
Q
C
G
--------
G
S
-
L
------------------
E
I
I
PC
S
R
V
G
H
-
V
F
R
K
Q
H
P
Y
T
F
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
65.19
22%
-62
- C2 -
5AJO
11
GALT2_HUMAN
A:
[133-370]
-----------------------------------------------------------------------------------------------------------------------------------------------
V
D
L
P
A
T
S
V
V
I
T
F
H
N
E
-
A
-
R
S
A
L
L
R
T
V
V
S
V
L
K
K
S
P
P
H
L
I
K
E
I
I
L
V
D
D
Y
S
N
-
D
P
E
-----
D
-
G
-----
A
L
L
G
K
I
E
K
-----------
V
R
V
L
R
N
----
D
R
R
---
E
G
L
M
R
S
R
V
R
G
A
D
A
A
Q
A
K
V
L
T
F
L
D
S
H
C
E
C
-
N
E
H
W
L
E
P
L
L
E
R
V
A
E
D
------------
R
T
-----
R
V
V
S
P
I
I
D
V
-----
I
N
-
M
D
NF
Q
Y
V
G
A
SAD
L
K
G
G
F
D
W
N
-----
L
-----
V
-------
F
K
-------
W
D
Y
M
T
P
E
Q
R
R
S
R
Q
G
N
-------
P
-
V
A
P
------------
I
K
-----------
T
P
M
I
A
------------------
G
G
L
F
V
M
D
K
F
Y
F
E
E
L
G
K
Y
D
M
M
---
M
---
D
VWG
G
---
E
N
L
E
I
S
F
R
V
W
-
Q
C
G
--------
G
S
-
L
------------------
E
I
I
PC
S
R
V
G
H
-
V
F
R
K
Q
H
P
Y
T
F
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
65.17
22%
-62
- C2 -
2FFU
3
GALT2_HUMAN
A:
[63-300]
-----------------------------------------------------------------------------------------------------------------------------------------------
V
D
L
P
A
T
S
V
V
I
T
F
H
N
E
-
A
-
R
S
A
L
L
R
T
V
V
S
V
L
K
K
S
P
P
H
L
I
K
E
I
I
L
V
D
D
Y
S
N
-
D
P
E
-----
D
-
G
-----
A
L
L
G
K
I
E
K
-----------
V
R
V
L
R
N
----
D
R
R
---
E
G
L
M
R
S
R
V
R
G
A
D
A
A
Q
A
K
V
L
T
F
L
D
S
H
C
E
C
-
N
E
H
W
L
E
P
L
L
E
R
V
A
E
D
------------
R
T
-----
R
V
V
S
P
I
I
D
V
-----
I
N
-
M
D
NF
Q
Y
V
G
A
SAD
L
K
G
G
F
D
W
N
-----
L
-----
V
-------
F
K
-------
W
D
Y
M
T
P
E
Q
R
R
S
R
Q
G
N
-------
P
-
V
A
P
------------
I
K
-----------
T
P
M
I
A
------------------
G
G
L
F
V
M
D
K
F
Y
F
E
E
L
G
K
Y
D
M
M
---
M
---
D
VWG
G
---
E
N
L
E
I
S
F
R
V
W
-
Q
C
G
--------
G
S
-
L
------------------
E
I
I
PC
S
R
V
G
H
-
V
F
R
K
Q
H
P
Y
T
F
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
Fugue
63.91
13%
-85
- C2 -
2Z86
4
CHS_ECOLX
A:
[4-625]
---------------------------------------------------------------IDID
A
A
T
K
I
M
C
S
N
A
KA
I
S
L
N
E
V
E
K
N
E
I
I
S
K
Y
R
E
I
T
A
K
K
S
-
E
R
A
E
L
K
E
V
E
P
I
P
L
D
W
P
S
D
LTLPPLPESTND
Y
V
W
A
G
K
R
K
E
L
L
I
I
D
G
L
S
I
V
I
P
T
Y
N
R
-
A
-
K
-
I
L
A
I
T
L
A
C
L
C
N
Q
K
T
I
-
Y
D
Y
E
V
I
V
A
D
D
G
S
K
-
E
-
N
-----
I
-
E
-----
E
I
V
R
E
F
E
S
L
L
----------
N
I
K
Y
V
----
R
Q
K
D
Y
G
Y
Q
L
C
A
V
R
N
L
G
L
R
A
A
K
Y
N
Y
V
A
I
L
D
C
D
M
A
P
-
N
P
L
W
V
Q
S
Y
M
E
L
L
A
V
D
D
N
V
A
L
I
G
P
R
K
Y
I
D
T
-----
S
K
H
T
Y
L
D
F
L
-----
S
Q
-
K
S
-----------------
L
-----
I
-----
N
-------
E
I
-------
P
---------
E
S
V
D
W
-------
R
-
I
E
H
------------
F
K
N
T
D
NLRLCNTP
F
R
F
F
S
------------------
G
G
N
V
A
F
A
K
K
W
L
F
R
A
G
W
F
D
E
E
FTH
W
---
G
---
G
---
E
D
N
E
F
G
Y
R
L
Y
-
R
E
G
--------
C
Y
-
F
------------------
R
S
----
V
E
G
A
M
A
Y
H
Q
E
P
P
Q
L
L
Q
Q
K
V
-
P
Y
F
Y
R
K
K
E
K
I
E
S
A
T
L
K
R
V
P
L
V
S
I
Y
I
P
A
Y
N
C
S
K
Y
I
-----
V
---
R
C
V
E
S
A
L
N
QTIT
D
L
E
V
C
I
C
D
D
---------
G
S
T
D
D
T
L
-----
R
I
L
Q
E
H
Y
ANHPR
V
R
F
I
S
Q
K
N
K
G
I
G
S
A
S
N
T
A
V
R
L
C
R
G
F
Y
I
G
Q
L
D
S
D
D
F
L
E
P
D
A
V
E
L
C
L
-----------
D
-----
E
F
R
K
D
L
------
S
L
A
C
V
Y
T
T
N
R
N
I
----------------
D
-------------------
R
E
G
N
L
I
S
N
G
Y
N
W
P
I
Y
S
R
E
K
L
T
S
AMICHHF
R
M
F
T
A
R
A
W
N
L
T
EGFNESISNA
V
D
Y
D
M
Y
L
K
L
S
E
V
G
P
F
K
H
I
NKIC
Y
N
R
V
L
HSI
K
K
L
D
I
Q
K
E
N
H
F
K
V
V
N
E
S
LSRLGIKKYKYSPLTNLNECR
K
Y
T
W
E
K
I------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
63.27
22%
-60
- C2 -
2FFV
2
GALT2_HUMAN
A:
[63-302]
-----------------------------------------------------------------------------------------------------------------------------------------------
V
D
L
P
A
T
S
V
V
I
T
F
H
N
E
-
A
-
R
S
A
L
L
R
T
V
V
S
V
L
K
K
S
P
P
H
L
I
K
E
I
I
L
V
D
D
Y
S
N
-
D
P
E
-----
D
-
G
-----
A
L
L
G
K
I
E
K
-----------
V
R
V
L
R
N
----
D
R
R
---
E
G
L
M
R
S
R
V
R
G
A
D
A
A
Q
A
K
V
L
T
F
L
D
S
H
C
E
C
-
N
E
H
W
L
E
P
L
L
E
R
V
A
E
D
------------
R
T
-----
R
V
V
S
P
I
I
D
V
-----
I
N
-
M
D
NFQ
Y
V
G
A
S
AD
L
K
G
G
F
D
W
N
-----
L
-----
V
-------
F
K
-------
W
D
Y
M
T
P
E
Q
R
R
S
R
Q
G
N
-------
P
-
V
A
P
------------
I
K
-----------
T
P
M
I
A
------------------
G
G
L
F
V
M
D
K
F
Y
F
E
E
L
G
K
Y
D
M
M
---
M
---
D
VWG
G
---
E
N
L
E
I
S
F
R
V
W
-
Q
C
G
--------
G
S
-
L
------------------
E
I
I
PC
S
R
V
G
H
-
V
F
R
K
Q
H
P
Y
T
F
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
42
HHSearch
62.96
23%
-79
* C2 *
2Z86
2
CHS_ECOLX
A:
[371-577]
----------------------------------------------------------------------------------------------------------------------------------------------
L
K
R
V
P
L
V
S
I
Y
I
P
A
Y
N
C
-
S
-
K
-
Y
I
V
R
C
V
E
S
A
L
N
Q
T
I
T
--
D
L
E
V
C
I
C
D
D
G
S
T
-
D
-
D
-----
T
-
L
-----
R
I
L
Q
E
H
Y
A
N
H
P
-----
R
--
V
R
F
I
--------
S
Q
K
N
K
G
I
G
S
A
S
N
T
A
V
R
L
C
R
G
F
Y
I
G
Q
L
D
S
D
D
F
L
-
E
P
D
A
V
E
L
C
L
D
E
F
R
K
D
L
S
L
A
C
V
Y
T
T
N
R
N
I
D
-----
R
E
G
N
L
I
S
N
G
-----
Y
N
-
W
P
-----------------
I
-----------------------------------------
Y
--------
S
-
R
E
K
------------
L
T
-----------
S
A
M
I
C
------------------
H
H
F
R
M
F
T
A
R
A
W
N
L
T
E
G
F
N
E
S
I--
S
---
N
---
A
---
V
D
Y
D
M
Y
L
K
L
S
-
E
V
G
---------
P
-
F
------------------
K
H
----
I
N
K
I
-
C
Y
N
R
V
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38
HHSearch
62.94
21%
-56
- C2 -
2D7I
5
GLT10_HUMAN
A:
[109-341]
-----------------------------------------------------------------------------------------------------------------------------------------------
E
T
L
P
N
T
S
I
I
I
P
F
H
N
E
-
G
W
S
-
S
L
L
R
T
V
H
S
V
L
N
R
S
P
P
E
L
V
A
E
I
V
L
V
D
D
F
S
D
-
R
-
E
-----
H
L
K
-----
K
P
L
E
D
Y
M
A
L
F
P
-----
S
--
V
R
I
L
-------
R
T
K
K
R
E
G
L
I
R
T
R
M
L
G
A
S
V
A
T
G
D
V
I
T
F
L
D
S
H
C
E
A
-
N
V
N
W
L
P
P
L
L
D
R
I
A
R
N
-
R
K
T
I
V
C
P
M
I
D
V
I
D
-----
H
D
D
F
R
Y
E
T
Q
AGD
A
M
R
G
A
F
D
-----------------
W
-----
E
-----
M
-------
Y
Y
K
R
I
P
IPP
E
---------
L
Q
K
A
D
-------
P
-
S
D
P
------------
F
E
-----------
S
P
V
M
A
------------------
G
G
L
F
A
V
D
R
K
W
F
W
E
L
G
G
Y
D
P
G
---
L
---
E
IWG
G
---
E
Q
Y
E
I
S
F
K
V
W
-
M
C
G
--------
G
R
-
M
------------------
E
D
----
I
P
C
S
-
R
V
G
H
I
Y
R
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
62.36
23%
-67
- C2 -
2D7R
5
GLT10_HUMAN
A:
[111-328]
-------------------------------------------------------------------------------------------------------------------------------------------------
L
P
N
T
S
I
I
I
P
F
H
N
E
-
G
W
S
-
S
L
L
R
T
V
H
S
V
L
N
R
S
P
P
E
L
V
A
E
I
V
L
V
D
D
F
S
D
R
E
-
H
-----
L
-
K
-----
K
P
L
E
D
Y
M
A
L
F
P
-----
S
--
V
R
I
L
R
T
----
K
K
R
---
E
G
L
I
R
T
R
M
L
G
A
S
V
A
T
G
D
V
I
T
F
L
D
S
H
C
E
A
-
N
V
N
W
L
P
P
L
L
D
R
I
--------------
A
R
N
-----
R
K
T
I
V
C
P
M
I
-----
D
V
-
I
D
-----------------
H
-----
D
-----
D
-------
F
R
-------
Y
---------
E
T
Q
A
G
D
A
M
R
G
A
F
D
-
W
E
M
Y-----------
Y
K
-----------
R
I
P
I
P
PELQKADPS
D
P
F
E
S
PVMA
G
G
L
F
A
V
D
R
K
W
F
W
E
L
G
G
Y
D
P
G
---
L
---
E
IWG
G
---
E
Q
Y
E
I
S
F
K
V
W
-
M
C
G
--------
G
R
-
M
------------------
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
39
HHSearch
61.74
23%
-65
- C2 -
1XHB
1
GALT1_MOUSE
A:
[24-271]
---------------------------------------------------------------------------------------------------------------------------------------------
Y
P
D
N
L
P
T
T
S
V
V
I
V
F
H
N
E
-
A
W
S
-
T
L
L
R
T
V
H
S
V
I
N
R
S
P
R
H
M
I
E
E
I
V
L
V
D
D
A
S
E
-
R
-
D
-----
F
L
K
-----
R
P
L
E
S
Y
V
K
K
L
K
-----
V
P
-
V
H
V
I
-------
R
M
E
Q
R
S
G
L
I
R
A
R
L
K
G
A
A
V
S
R
G
Q
V
I
T
F
L
D
A
H
C
E
C
-
T
A
G
W
L
E
P
L
L
A
R
I
K
H
D
R
-
R
T
V
V
C
P
I
I
D
V
I
S
-----
D
D
T
F
E
Y
M
A
G
-----
S
D
-
M
T
-----------------
Y
G
G
F
N
W
K
-----
L
N
F
R
W
Y
P
V
P
Q
-------
R
E
M
D
------
R
R
K
G
D
-------
R
-
T
L
P
------------
V
R
-----------
T
P
T
M
A
------------------
G
G
L
F
S
I
D
R
D
Y
F
Q
E
I
G
T
Y
D
A
G
---
M
DIW
G
---
G
---
E
N
L
E
I
S
F
R
I
W
-
Q
C
G
--------
G
T
-
L
------------------
E
I
----
V
T
C
S
-
H
V
G
H
V
F
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
61.37
23%
-67
- C2 -
2D7I
5
GLT10_HUMAN
A:
[111-328]
-------------------------------------------------------------------------------------------------------------------------------------------------
L
P
N
T
S
I
I
I
P
F
H
N
E
-
G
W
S
-
S
L
L
R
T
V
H
S
V
L
N
R
S
P
P
E
L
V
A
E
I
V
L
V
D
D
F
S
D
R
E
-
H
-----
L
-
K
-----
K
P
L
E
D
Y
M
A
L
F
P
-----
S
--
V
R
I
L
R
T
----
K
K
R
---
E
G
L
I
R
T
R
M
L
G
A
S
V
A
T
G
D
V
I
T
F
L
D
S
H
C
E
A
-
N
V
N
W
L
P
P
L
L
D
R
I
--------------
A
R
N
-----
R
K
T
I
V
C
P
M
I
-----
D
V
-
I
D
-----------------
H
-----
D
-----
D
-------
F
R
-------
Y
---------
E
T
Q
A
G
D
A
M
R
G
A
F
D
-
W
E
M
Y-----------
Y
K
-----------
R
I
P
I
P
PELQKADPS
D
P
F
E
S
PVMA
G
G
L
F
A
V
D
R
K
W
F
W
E
L
G
G
Y
D
P
G
---
L
---
E
IWG
G
---
E
Q
Y
E
I
S
F
K
V
W
-
M
C
G
--------
G
R
-
M
------------------
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
43
HHSearch
61.29
19%
-80
- C2 -
3CKJ
5
GPGS_MYCPA
A:
[43-268]
---------------------------------------------------------------------------------------------------------------------------------------------
A
A
K
A
G
R
T
I
S
V
V
L
P
A
L
D
E
-
E
-
D
-
T
I
G
S
V
I
D
S
I
S
P
L
V
D
G
L
-
V
D
E
L
I
V
L
D
S
G
S
T
-
D
-
D
-----
T
-
E
-----
I
R
A
V
A
A
G
------------
A
R
V
V
S
R
EQAL
P
E
V
P
I
R
P
G
K
G
E
A
L
W
R
S
L
A
A
S
R
G
D
I
V
V
F
V
D
S
D
L
I
N
P
H
P
M
F
V
P
W
L
V
G
P
L
L
T
G
D
G
V
H
L
V
K
S
F
Y
R
R
P
--------------------
G
R
-
V
T
-----------------
E
-----
L
-----
V
-------
A
R
-------
P
---------
L
L
A
A
L
-------
R
-
P
E
L
------------
G
C
-----------
I
L
Q
P
L
------------------
G
G
E
Y
A
A
T
R
E
L
L
T
S
V
-
P
F
A
P
G
-------
Y
---
G
---
V
E
I
G
L
L
V
D
T
F
D
R
L
G
--------
L
D
A
I
------------------
A
Q
----
V
N
L
G
-
V
R
E
H
R
N
R
P
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------