@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv0093c: (2016-04-19 )
MLAQATTAGSFNHHASTVLQGCRGVPAAMWSEPAGAIRRHCATIDGMDCEVAREALSARLDGERAPVPSARVDEHLGECSACRAWFTQVASQAGDLRRLAESRPVVPPVGRLGIRRAPRRQHSPMTWRRWALLCVGIAQIALGTVQGFGLDVGLTHQHPTGAGTHLLNESTSWSIALGVIMVGAALWPSAAAGLAGVLTAFVAILTGYVIVDALSGAVSTTRILTHLPVVIGAVLAIMVWRSASGPRPRPDAVAAEPDIVLPDNASRGRRRGHLWPTDGSAA
Atome Classification :
(20 SA)
---------------------.........10........20........30--------........40..--......50--.........60........70........80.....----------...-------90........100-.-----------------.......-110----........120---......--.130........140-.........150.......160..-.....170-........-.180.....--------..190....----...200-....-..-----...210...-----------....-----220--.........230------------.......240........250..-----.-....260----.......270.......280-----------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---------------------MLAQATTAGSFN
H
H
A
S
T
V
L
Q
GCRGV
P
A
A
M
WS--------E
P
A
G
A
I
R
R
H
C
AT--IDGM
D
C
E
---
V
A
R
E
A
L
S
A
RLDGERAPVP
S
A
R
V
D
E
H
L
G
E
C
S
A
C
R
A
W
F
----------
T
Q
V
-------
A
S
Q
A
G
D
L
R
R
L
A
E--S-----------------RPVVPPV-
G
R
-----LGIRRAPRRQH---SP
M
T
W
R
--
R
W
-
A
L
L
C
V
G
I
A
Q
I
---
A
L
G
TVQGFGLDVGLTHQHPTGAGT-HLLNES---TS
W
S
I
A
L
G
-
V
I
M
V
G
A
ALW--------
P
S
A
A
A
G
L
A
G
----
V
L
T
A
---
F
V
A
I
-
L
T
-----
G
Y
V
I
V
D
A
LS-----------G
A
V
S
-----
T
----
T
R
I
L
T
H
L
P
V
V
I
G
------------
A
V
L
A
I
M
V
WR-SASGPRPRPDAVA-----A-EP
D
I
VLP----DNASRGRRRGHLWPTDGSAA-----------------
37
Fugue
75.99
23%
-84
* C4 *
4RGL
1
?
A:
[8-335]
---------------------
Y
Q
P
P
Y
T
I
T
P
A
I
V
N
L
V
A
E
I
G
E
I
I
G
R
Y
T
V
L
A
E
Q
--------
N
L
T
P
R
L
R
R
E
-
N
R
--
I
R
T
I
Q
A
S
---
L
A
I
E
N
N
T
L
T
L
E
Q
V
T
A
V
I
D
G
K
R
V
L
G
H
P
R
E
I
Q
E
V
R
N
A
F
----------
A
T
Y
E
A
MEDWD
A
S
V
E
G
D
L
L
A
A
H
E
--
L
L
M
---------------
R
G
L
V
D
E
T
-
G
R
YRS
G
G
V
G
I
F
R
G
E
Q
L
V
H
M
--
A
P
P
A
D
R
V
P
K
L
M
A
D
L
L
D
W
L
E
N
T
NEH
P
L
V
A
S
C
I
F
H
Y
E
F
E
F
I
H
P
F
A
D
G
N
G
R
M
G
R
L
W
Q
T
L
I
L
R
N
W
K
P
L
L
A
-
Y
L
P
V
E
T
V
I
R
D
R
Q
E
D
Y
Y
R
V
L
A
V
A
D
S
Q
A
----
D
A
T
P
---
F
V
E
F
M
L
-------
G
A
L
R
D
A
V
R
-----------
E
A
V
S
-----
T
D
HQV
T
D
Q
V
A
A
L
I
R
A
I
G
------------
G
G
E
L
S
S
N
D
L
M
Q
A
L
G
L
S
H
R
P
T
F
R
N
NY
L
N
P
A
M
E
D
E
W
I
E
R
----
T
Q
P
D
S
P
R
S
P
T
Q
R
Y
R
L
T
G
K
G
Q
R----------------
38
Fugue
65.84
20%
-84
- C4 -
1YAR
-
?
O:
[10-237]
---------------------
K
R
A
A
L
I
Q
N
L
R
D
S
Y
T
E
T
S
S
F
A
V
I
E
E
W
A
A
G
T
L
Q
--------
E
I
E
G
-
I
A
K
A
A
A
E
--
A
H
G
-------
V
I
R
N
S
T
Y
G
R
A
Q
A
E
K
S
P
------
E
Q
L
L
G
V
L
Q
R
Y
Q
D
L
C
----------
H
N
V
-------
Y
C
Q
A
E
T
I
R
T
V
I
A
-------------------------------------
I
R
I
P
E
H
K
E
E
---
D
N
L
G
V
A
--
V
Q
-
H
A
V
L
K
I
I
D
E
L
---
E
I
K
T
L
-
G
S
G
E
K
S
G
-
S
G
G
A
P
T
P
I
G
M
-
Y
A
L
R
E
Y
---
L
S
A
R
S
T
V
E
-
D
K
L
L
G
G
G
S
Q
--------
S
--------------
P
S
---
L
L
L
E
-
L
R
-----
Q
I
D
A
D
F
M
L
K
-----------
V
E
L
A
-----
T
----
T
H
L
S
T
M
V
R
A
V
I
N
------------
A
Y
L
--
L
N
W
K
-
K
L
I
Q
P
R
T
G
S
D
H
M
V
-----
S
-------------------------------------------------
36
Fugue
48.29
14%
-85
* C5 *
1EZ1
7
PURT_ECOLI
A:
[2-392]
T
L
L
G
T
ALRPAAT
R
V
M
L
LGSG
E
L
G
K
E
V
A
I
E
C
Q
R
L
G
V
E
V
I
A
V
D
R
Y
A
D
A
P
A
M
H
V
A
H
R
S
H
V
I
NM
L
D
G
D
A
L
R
R
V
V
E
L
E
K
P
H
Y
I
V
P
E
IEA
I
A
T
D
M
L
I
Q
L
E
E
E
G
L
N
V
V
P
C
A
R
A
T
K
L
T
M
N
R
E
G
I
R
R
L
A
A
EELQLPT
S
T
Y
R
F
-------
A
D
S
E
S
L
F
R
E
A
V
A
--
D
I
GYP
C
I
V
K
P
VMSSSGKG
Q
T
F
I
R
S
A
-
E
Q
-----
L
A
Q
A
W
K
Y
A
Q
Q
G
GRA
G
R
V
I
V
E
--
G
V
-
V
K
F
D
F
E
I
T
L
L
---
T
V
S
A
V
D
G
V
H
F
C
A
P
V
G
H
R
Q
E
D
G
-
D
Y
-
R
E
S
W
Q
P
---
Q
Q
M
S
P
L
A
L
-
E
R
A
Q
E
I
A
R
K
--------
V
V
L
A
L
G
G
Y
G
----
L
F
G
V
---
E
L
F
V
-
C
G
-----
D
E
V
I
F
S
E
V
S
PRPHDTGMVTL
I
S
Q
D
-----
L
----
S
E
F
A
L
H
V
R
A
F
L
G
LPVG
G
I
R
Q
Y
G
P
A
A
S
A
V
I
L
P
Q
L
-
T
S
Q
N
V
T
F
D
N
V
Q
N
A
-----
V
-
G
A
D
L
Q
I
R
L
FGK
P
E
I
D
G
S
R
R
L
G
V
A
L
A
T
A
E
S
V
V
D
A
I
E
R
A
K
H
A
A
G
Q
VKVQG
26
HHSearch
43.68
22%
-32
* C3 *
2Q1Z
1
CHRR_RHOS4
B:
[2-76]
----------------------------------------------------------------------------
T
I
R
H
H
---
V
S
D
A
L
L
T
A
Y
A
A
G
T
L
S
E
A
F
S
L
V
V
A
T
H
L
S
L
C
D
E
C
R
A
R
A
----------
G
A
L
-------
D
A
V
G
G
S
L
M
E
E
T
A
P
V
A
-----------------
L
S
--
E
G
S
-
L
A
-----
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
42.43
32%
-147
- C3 -
4AIN
-
BETP_CORGL
A:
[210-286]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
A
C
S
L
G
L
G
-
A
L
Q
I
G
A
G
L
----------
S
A
A
N
--
E
D
PSD
W
T
I
V
G
---
I
V
S
V
-
L
T
-----
L
A
F
I
F
S
A
I
S
--------------
K
-----
G
----
I
Q
Y
L
S
N
A
N
M
V
L
A
------------
A
L
L
A
I
F
V
F
----------------------------------------------------------------------
23
PsiBlast_CBE
41.93
32%
-138
- C3 -
4AIN
1
BETP_CORGL
B:
[210-281]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
A
C
S
L
G
L
G
-
A
L
Q
I
G
A
G
L
----------
S
A
A
N
I
I
E
D
PS
D
W
T
I
V
G
---
I
V
S
V
-
L
T
-----
L
A
F
I
F
S
A
I
S
-----------
G
V
G
K
-----
G
----
I
Q
Y
L
S
N
A
N
M
V
L
A
------------
A
L
L
A
I
F
V
F
----------------------------------------------------------------------
16
PsiBlast_CBE
41.76
32%
-148
- C3 -
4LLH
1
BETP_CORGL
C:
[221-292]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
A
C
S
L
G
L
G
-
A
L
Q
I
G
A
G
L
----------
S
A
A
N
I
---PS
D
W
T
I
V
G
---
I
V
S
V
-
L
T
-----
L
A
F
I
F
S
A
I
S
--------------------
G
----
I
Q
Y
L
S
N
A
N
M
V
L
A
------------
A
L
L
A
I
F
V
F
----------------------------------------------------------------------
12
PsiBlast_PDB
41.11
32%
-125
- C3 -
4C7R
-
BETP_CORGL
A:
[221-292]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
A
C
S
L
G
L
G
-
A
L
Q
I
G
A
G
L
----------
S
A
A
N
I
I
E
D
PS
D
W
T
I
V
G
---
I
V
S
V
-
L
T
-----
L
A
F
I
F
S
A
I
S
-----------
G
V
G
K
-----
G
----
I
Q
Y
L
S
N
A
N
M
V
L
A
------------
A
L
L
A
I
F
V
F
----------------------------------------------------------------------
43
Fugue
40.94
13%
-92
- C4 -
1GUX
-
?
A:
[9-206]
---------------------------------------------------------------------------------------------------------------------------------------------
N
T
I
Q
Q
L
M
M
I
L
N
--
S
-----------------
A
S
D
Q
P
S
E
-
N
L
-----
I
S
Y
F
N
N
C
T
V
N
P
---
K
E
S
I
L
K
--
R
V
-
K
D
I
G
Y
I
F
K
E
K
---
F
A
K
A
V
G
Q
G
C
V
E
I
G
S
Q
R
Y
K
L
G
V
R
L
Y
-
Y
R
V
M
E
S
---
M
L
K
S
E
N
F
S
-
K
L
L
N
D
N
I
F
H
--------
M
S
L
L
A
C
A
L
E
----
V
V
M
A
T
Y
S
F
P
W
I
-
L
N
V
L
NLK
A
F
D
F
Y
K
V
I
E
-----------
S
F
I
K
A
E
GNL
T
----
R
E
M
I
K
H
L
E
R
C
E
H
------------
R
I
M
E
S
L
A
W
L
-
S
D
S
P
L
F
D
L
I
K
Q
S
K
-------------------------------------------------------
29
HHSearch
40.49
16%
-42
- C3 -
1OR7
-
RSEA_ECOLI
C:
[2-58]
-------------------------------------------------------------------------------------
Q
K
E
Q
L
S
A
L
M
D
G
E
T
L
D
S
E
---
L
L
N
E
L
A
H
N
P
E
M
Q
K
T
W
----------
E
S
Y
-------
H
L
I
R
D
S
M
R
G
D
T
P
E-
V
-----------------
L
H
--
F
D
I
-
S
S
-----
R
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_CBE
40.26
32%
-122
- C3 -
4C7R
1
BETP_CORGL
C:
[221-292]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
A
C
S
L
G
L
G
-
A
L
Q
I
G
A
G
L
----------
S
A
A
N
I
I
E
D
PSDW
T
I
V
G
---
I
V
S
V
-
L
T
-----
L
A
F
I
F
S
A
I
S
-----------
G
V
G
K
-----
G
----
I
Q
Y
L
S
N
A
N
M
V
L
A
------------
A
L
L
A
I
F
V
F
----------------------------------------------------------------------
21
PsiBlast_CBE
39.64
32%
-133
- C3 -
4C7R
1
BETP_CORGL
B:
[221-292]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
A
C
S
L
G
L
G
-
A
L
Q
I
G
A
G
L
----------
S
A
A
N
I
I
E
D
PSDW
T
I
V
G
---
I
V
S
V
-
L
T
-----
L
A
F
I
F
S
A
I
S
-----------
G
V
G
K
-----
G
----
I
Q
Y
L
S
N
A
N
M
V
L
A
------------
A
L
L
A
I
F
V
F
----------------------------------------------------------------------
10
PsiBlast_PDB
39.02
32%
-138
- C3 -
4DOJ
-
BETP_CORGL
A:
[221-292]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
A
C
S
L
G
L
G
-
A
L
Q
I
G
A
G
L
----------
S
A
A
N
-
I
E
D
PSDW
T
I
V
G
---
I
V
S
V
-
L
T
-----
L
A
F
I
F
S
A
I
S
-----------
G
V
G
K
-----
G
----
I
Q
Y
L
S
N
A
N
M
V
L
A
------------
A
L
L
A
I
F
V
F
----------------------------------------------------------------------
40
Fugue
38.28
11%
-91
- C1 -
2WLG
10
OATWY_NEIME
A:
[5-215]
----------------------------
M
Y
S
E
Q
G
I
N
N
T
I
N
I
S
----------------------------
T
T
--
S
L
T
N
A
T
Q
---
L
T
V
I
G
N
N
N
S
V
Y
I
G
N
--
N
C
K
I
V
S
S
N
I
R
L
K
G
N
N
I
T
L
F
I
----------
A
D
D
-------
V
----------
E
--
I
-----------------
M
G
L
V
C
S
L
H
S
D
-----
C
S
L
Q
I
Q
A
K
T
T
M
---
G
N
---
G
--
E
I
-
T
I
A
E
K
G
K
I
S
I
---
G
K
D
C
M
L
A
H
G
Y
E
I
R
N
T
D
M
H
P
I
Y
S
L
E
-
N
G
E
R
I
N
---
H
G
K
D
V
I
I
G
N
H
V
W
L
G
R
N
V
----------------------
T
I
L
K
---
G
V
C
I
-
P
N
-----
N
V
V
V
G
---
S
-----------
H
T
V
L
-----
Y
----
K
S
F
K
E
P
N
C
V
I
A
G
------------
S
P
A
K
I
V
K
E
N
-
I
V
W
G
R
K
M
Y
H
S
T
M
Y
-----
D
-
D
P
T
L
N
E
F
----
Y
K
-----------------------------------
8
PsiBlast_PDB
37.75
32%
-128
- C3 -
3P03
-
BETP_CORGL
A:
[221-309]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
A
C
S
L
G
L
G
-
A
L
Q
I
G
A
G
L
----------
S
A
A
N
----DW--
T
I
V
G
---
I
V
S
V
-
L
T
-----
L
A
F
I
F
S
A
I
S
-----------
G
V
G
K
-----
G
----
I
Q
Y
L
S
N
A
N
M
V
L
A
------------
A
L
L
A
I
F
V
F
----------------------------------------------------------------------
41
Fugue
37.13
13%
-123
- C5 -
3HZQ
-
MSCL_STAAW
A:
[1-94]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
L
K
E
F
K
-
E
F
A
L
K
G
---
N
V
L
D
L
A
I
A
-
V
V
M
-
G
A
A
F
N
--------
K
I
I
C
S
L
V
E
N
----
I
I
M
P
---
L
I
G
K
-
I
F
-----
G
S
V
D
F
A
K
E
W
-----------
S
F
W
G
-----
I
KYG-
L
F
I
Q
S
V
I
D
F
I
I
I
------------
A
F
A
L
F
I
F
V
K
-
I
A
N
T
L
M
K
K
E
-----------------------------------------------------------
27
HHSearch
36.07
18%
-15
- C3 -
3HUG
1
RSLA_MYCTU
B:
[25-74]
--------------------------------------------------------------------------------
H
---
H
Y
A
M
W
D
A
A
Y
V
L
G
A
L
S
A
A
D
R
R
E
F
E
A
H
L
A
G
C
P
E
C
R
G
A
V
----------
T
E
L
-------
C
G
V
P
A
L
L
S
Q
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
35.86
32%
-120
- C3 -
4LLH
-
BETP_CORGL
A:
[221-292]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
A
C
S
L
G
L
G
-
A
L
Q
I
G
A
G
L
----------
S
A
A
---
E
D
P
S
D
W
T
I
V
G
---
I
V
S
V
-
L
T
-----
L
A
F
I
F
S
A
I
S
-----------
G
V
G
K
-----
G
----
I
Q
Y
L
S
N
A
N
M
V
L
A
------------
A
L
L
A
I
F
V
F
----------------------------------------------------------------------
31
HHSearch
35.73
12%
-13
- C3 -
5COS
-
?
A:
[15-64]
--------------------------------------------------------------------------------
E
---
Q
A
M
H
W
H
L
E
L
Q
E
P
A
V
S
A
A
T
L
A
A
C
M
S
W
R
Q
A
H
P
L
H
E
H
A
W
----------
Q
R
T
-------
Q
V
F
A
Q
R
L
R
E
M
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
35.60
30%
-14
- C3 -
1GVY
3
MANA_CELJU
A:
[245-289]
-----------------------------------------------------------------------------------------------------------
D
T
Y
G
P
V
A
D
N
A
D
W
F
----------
R
N
V
-------
V
A
N
A
A
L
V
A
R
M
A
E
--
A
-----------------
R
G
K
I
P
V
I
-
S
E
-----
I
G
I
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------