@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv0123: (2016-04-19 )
MTKKPRNPADYVIGDDVEVSDVDLKQEEVYVDGERLTDERVEQMASESLRLAREREANLIPGGKSLSGGSAHSPAVQVVVSKATHAKLKELARSRKMSVSKLLRPVLDEFVQRETGRILPRR
Atome Classification :
(20 SA)
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10........20..--......30--......-----------...40........50........-------60----.........70.......-.80.......-------.90......-..100--------------------.........110.......120---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTKKPRNPA
D
Y
VIGDDVEVSDVD--LKQ
E
E
V
Y
---VD
G
E
RL-----------
T
D
E
R
V
E
Q
M
A
S
E
S
L
R
L
A
R
EREANL-------I-----PGGKSLSGGSAHS
P
A
V
Q
V
-
V
VSKA
T
H
A
K
L
-------
K
E
L
A
R
SRK
M
-
S
V
S
----------------------
K
L
L
R
P
V
L
D
E
F
V
Q
R
E
TGRILPRR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
65.34
30%
-45
- C5 -
1E4F
-
?
T:
[270-345]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
--
L
K
E
E
E
I
Q
YRG
L
D
G
N
T
I
KTTTAKKLSVI
I
H
A
R
L
R
E
I
M
S
K
S
K
K
F
F
R
E
V
E
A
K
-IG-----
I
-----
P
G
G
V
V
L
T
G
G
G
A
K
I
P
R
I
N
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
64.55
30%
-48
- C5 -
4A2B
1
?
A:
[270-345]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
--
L
K
E
E
E
I
Q
Y
R
G
L
D
G
N
T
I
K
T
T
T
A
K
K
L
S
V
I
I
H
A
R
L
R
E
I
M
S
K
S
K
K
F
F
R
E
V
E
A
K
I
V
E
E
GEIG
I
-----
P
G
G
V
V
L
T
G
G
G
A
K
I
P
R
I
N
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
63.17
30%
-35
- C5 -
4A2A
2
?
A:
[270-345]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
--
L
K
E
E
E
I
Q
Y
R
G
L
D
G
N
T
I
K
T
T
T
A
K
K
L
S
V
I
I
H
A
R
L
R
E
I
M
S
K
S
K
K
F
F
R
E
V
E
A
K
--------
I
-----
P
G
G
V
V
L
T
G
G
G
A
K
I
P
R
I
N
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
62.56
30%
-45
- C5 -
1E4G
1
?
T:
[270-345]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
--
L
K
E
E
E
I
Q
YRG
L
D
G
N
T
I
KTTTAKKLSVI
I
H
A
R
L
R
E
I
M
S
K
S
K
K
F
F
R
E
V
E
A
K
-G------
I
-----
P
G
G
V
V
L
T
G
G
G
A
K
I
P
R
I
N
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
HHSearch
61.40
18%
-97
- C5 -
3H87
4
VAPB2_MYCTU
C:
[2-45]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
D
V
L
I
R
D
I
P
D
D
V
L
A
S
L
-------
D
A
I
A
A
R
L
G
L
-
S
R
T
----------------------
E
Y
I
R
R
R
L
A
Q
D
A
Q
T
A
R
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
60.87
17%
-85
- C5 -
2K9I
-
?
A:
[2-54]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
R
P
Y
K
L
---
L
N
G
I
K
L
G
V
-
Y
I
P
Q
E
W
H
D
R
L
-------
M
E
I
A
K
E
K
N
L
-
T
L
S
----------------------
D
V
C
R
L
A
I
K
E
Y
L
D
N
H
D
K
Q
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
57.60
15%
-84
- C5 -
1BAZ
-
RARC_BPP22
A:
[5-50]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
K
M
P
Q
V
N
L
-
R
W
P
R
E
V
L
D
L
V
-------
R
K
V
A
E
E
N
G
R
-
S
V
N
----------------------
S
E
I
Y
Q
R
V
M
E
S
F
K
K
E
G
R
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
41
Fugue
56.68
17%
-100
- C5 -
3FT7
1
?
A:
[7-51]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
N
G
I
K
L
G
V
-
Y
I
P
Q
E
W
H
D
R
L
-------
M
E
I
A
K
E
K
N
L
-
T
L
S
----------------------
D
V
C
R
L
A
I
K
E
Y
L
D
N
H
D
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
HHSearch
56.09
19%
-84
- C5 -
3QOQ
2
?
A:
[16-62]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
R
T
A
D
K
F
V
V
-
R
L
P
E
G
M
R
E
Q
I
-------
A
E
V
A
R
S
H
H
R
-
S
M
N
----------------------
S
E
I
I
A
R
L
E
Q
S
L
L
Q
E
G
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
HHSearch
55.53
16%
-80
- C5 -
1P94
-
?
A:
[25-75]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
T
A
P
V
-
S
--
S
G
K
I
K
R
V
N
V
-
N
F
D
E
E
K
H
T
R
F
-------
K
A
A
C
A
R
K
G
T
-
S
I
T
----------------------
D
V
V
N
Q
L
V
D
N
W
L
K
E
N
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
49
Fugue
53.84
13%
-20
- C1 -
2B3W
-
RIBX_ECOLI
A:
[1-168]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPVRAQRIQHVMQDTIINFY
S
T
S
D
D
Y
G
D
F
S
N
F
A
A
W
P
I
K
V
D
G
K
T
--
W
P
T
S
E
H
Y
---
F
Q
A
Q
K
F
-----------
L
D
E
K
Y
R
E
E
I
R
R
V
---
S
S
P
M
V
A
A
R
-------
M
-----
G
R
D
R
S
K
P
L
R
K
N
W
E
S
V
K
E
Q
-
V
M
R
K
A
L
R
A
K
F
E
Q
H
A
E
L
R
A
L
L
L
A
T
A
P
A
-
K
L
V
E
H
T
ENDAYWGDGGHGKGKN
R
L
G
Y
L
L
M
E
L
R
E
Q
L
A
I
E
K
L
E
H
H
H
H
H
H
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
45
Fugue
53.84
22%
-3
- C3 -
4TZ4
-
DDB1_HUMAN
A:
[1-1146]
S
Y
N
Y
V
V
T
AQKPTAVN
G
C
V
T
G
HFTSAE
D
L
N
L
L
I
A
KNT
R
L
E
I
Y
V
V
T
ALRPV
K
E
V
G
M
YGKIA
V
M
E
L
F
R
P
K
GES
K
D
L
L
F
I
L
T
AKY
N
A
C
I
L
E
Y
K
QS
I
D
I
I
T
R
A
H
G
N
VQDRIGRPSET
G
I
I
G
I
I
D
PECR
M
I
G
L
R
LYDG
L
F
K
V
I
P
LDRDNKEL
K
A
F
N
I
R
L
EELHVI
D
V
K
F
L
Y
GCQ
A
P
T
I
C
F
V
Y
Q
D
PQ
G
R
H
V
K
T
Y
E
V
S
LREKEFNKGPWKQNVEAEAS
M
V
I
A
V
P
EPF
G
G
A
I
I
I
G
QE
S
I
T
Y
H
N
GD
K
Y
L
A
I
A
P
PIIKQ
S
T
I
V
C
HNRVDPNGS
R
Y
L
L
G
D
ME
G
R
L
F
M
L
L
L
E
KTLK
D
L
R
V
E
L
LGETSIAE
C
L
T
Y
L
D
NG
V
V
F
V
G
S
RL
G
D
S
Q
L
V
K
L
NEQ
G
S
Y
V
V
A
M
E
T
F
T
N
LGPIV
D
M
C
V
V
DLEQ
G
Q
L
V
T
CSGAFKE
G
S
L
R
I
I
R
N
G
I
G
I
H
E
H
A
S
I
D
L
P
GIK
G
L
W
P
L
R
SDPETDD
T
L
V
L
S
F
V
G
Q
T
R
V
L
M
L
N
G
E
E
V
E
E
T
E
L
M
GF
V
D
D
Q
Q
T
F
---
F
C
G
-
N
V
-----------
A
H
Q
Q
L
I
Q
I
T
S
A
S
V
R
L
V
S
Q
E
P
K
A
L
-------
V
S
E
W
K
E
P
Q
A
K
N
I
S
V
A
S
C
N
S
S
Q
V
V
V
-
A
V
G
R
A
L
Y
Y
L
Q
-------
I
H
P
Q
E
L
R
Q
I
-
S
H
T
----------------------
E
M
E
V
A
C
L
D
---------
I
T
P
L
G
LSP
L
C
A
I
G
LTDISA
R
I
L
K
L
PSFELHKEMLGGIIPR
S
I
L
M
T
T
F
ES
S
H
Y
L
L
C
A
L
GDG
A
L
F
Y
F
G
L
N
IETGLLSDK
K
V
T
L
G
TQ
P
T
V
L
R
T
F
R
SS
T
T
N
V
F
A
C
S
D
R
P
T
V
I
Y
SNH
K
L
V
F
S
N
V
NLKEVN
Y
M
C
P
L
N
S
DGYPD
S
L
A
L
A
N
NS
T
L
T
I
G
T
I
D
E
I
Q
K
L
H
I
R
T
V
P
LY
E
S
P
R
K
I
C
Y
Q
EVSQ
C
F
G
V
L
S
S
R
I
E
V
Q
DTTALRPSASTQAL
S
S
S
V
SSE
E
V
E
V
H
N
L
L
I
I
D
QHTFEVL
H
A
H
Q
F
L
QN
E
Y
A
L
S
L
V
S
C
K
L
GKDP
N
T
Y
F
I
V
G
T
A
M
V
Y
PEEAEPK
Q
G
R
I
V
V
F
Q
Y
S
DGKLQTV
A
E
K
E
V
KGAVY
S
M
V
E
F
NG
K
L
L
A
S
I
NS
T
V
R
L
Y
E
W
T
TEK
E
L
R
T
E
C
N
H
Y
N
NIMAL
Y
L
K
T
K
GD
F
I
L
V
G
D
LMR
S
V
L
L
L
A
Y
K
PMEG
N
F
E
E
I
A
R
D
F
N
P
N
WMS
A
V
E
I
LDDD
N
F
L
G
A
E
N
AF
N
L
F
V
C
Q
KDEERQHLQEV
G
L
F
HLGEFVN
V
F
C
H
G
S
LVT
Q
G
S
V
L
F
G
T
VNG
M
I
G
L
V
T
S
L
S
E
S
W
Y
N
L
L
L
D
M
Q
N
R
L
N
K
V
IKSVGKIE
H
S
F
W
R
SFHTKTEPATGFID
G
D
L
I
E
S
F
LDIS
R
P
K
M
Q
E
V
V
A
N
L
Q
Y
D
D
GKREAT
A
D
D
L
I
K
V
V
E
E
L
T
R
I
H
W
S
H
P
Q
FE
36
HHSearch
53.68
13%
-105
- C5 -
2WVF
3
NIKR_HELPY
A:
[9-56]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
I
I
R
F
S
V
-
S
L
Q
Q
N
L
L
D
E
L
-------
D
N
R
I
I
K
N
G
Y
S
S
R
S
----------------------
E
L
V
R
D
M
I
R
E
K
L
V
E
D
N
W
A
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
HHSearch
53.50
15%
-51
- C5 -
1MNT
-
RMNT_BPP22
A:
[3-48]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
D
P
H
F
N
F
-
R
M
P
M
E
V
R
E
K
L
-------
K
F
R
A
E
A
N
G
R
-
S
M
N
----------------------
S
E
L
L
Q
I
V
Q
D
A
L
S
K
P
S
P
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
HHSearch
53.15
13%
-93
- C5 -
2AY0
2
PUTA_ECOLI
A:
[3-45]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
T
T
M
G
V
-
M
L
D
D
A
T
R
E
R
I
-------
K
S
A
A
T
R
I
D
R
-
T
P
H
----------------------
W
L
I
K
Q
A
I
F
S
Y
L
E
Q
L
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
52.55
13%
-66
- C5 -
2BA3
-
?
A:
[3-50]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
A
V
R
K
K
S
E
V
R
Q
K
T
V
V
R
T
L
-
R
F
S
P
V
E
D
E
T
I
-------
R
K
K
A
E
D
S
G
L
-
T
V
S
----------------------
A
Y
I
R
N
A
A
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
42
Fugue
52.18
15%
-69
- C5 -
2JXG
-
?
A:
[1-45]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
A
T
T
T
L
G
V
-
K
L
D
D
P
T
R
E
R
L
-------
K
A
A
A
Q
S
I
D
R
-
T
P
H
----------------------
W
L
I
K
Q
A
I
F
N
Y
L
E
K
L
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
HHSearch
51.49
13%
-94
- C5 -
2GPE
1
PUTA_ECOLI
A:
[2-48]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
T
T
T
M
G
V
-
K
L
D
D
A
T
R
E
R
I
-------
K
S
A
A
T
R
I
D
R
-
T
P
H
----------------------
W
L
I
K
Q
A
I
F
S
Y
L
E
Q
L
E
N
S
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
HHSearch
51.05
13%
-53
- C5 -
1NLA
-
RARC_BPP22
A:
[5-51]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
K
M
P
Q
F
L
N
-
R
W
P
R
E
V
L
D
L
V
-------
R
K
V
A
E
E
N
G
R
-
S
V
N
----------------------
S
E
I
Y
Q
R
V
M
E
S
F
K
K
E
G
R
I
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
HHSearch
50.47
21%
-68
- C5 -
2K1O
-
?
A:
[22-69]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
N
F
S
V
T
F
-
Y
L
S
K
E
E
H
D
V
L
-------
R
R
L
A
D
E
E
V
E
-
S
V
N
----------------------
S
F
V
K
R
H
I
L
K
T
I
I
Y
K
K
G
T
N
Q
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------