@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv1491c: (2016-05-02 )
MTAPAICNTTETVHGIATSLGAVARQASLPRIVGTVVGITVLVVVALLVPVPTAVELRDWAKSLGAWFPLAFLLVHTVVTVPPFPRTAFTLAAGLLFGSVVGVFIAVVGSTASAVIAMLLVRATGWQLNSLVRRRAINRLDERLRERGWLAILSLRLIPVVPFAAINYAAGASGVRILSFAWATLAGLLPGTAAVVILGDAFAGSGSPLLILVSVCTGALGLTGLVYEIRNYRRQHRRMPGYDDPVREPALI
Atome Classification :
(18 SA)
-----------------------------------------.......--..10.......-.20-------.......-.-.30........40----........----.50--........60.......----.70..--------......80---.....-...90.....-------...100..--------------------.....110...--------....120...--......130-..--------.--..--...140....------------...150..-...----..160.......170----.........-----------180-.---------.......190......----.200-.......210.....----..220...-....230.......240.......250----------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-----------------------------------------MTAPAIC--NT
T
E
T
V
H
G
I
A
T
-
S
L
--------
G
A
V
A
R
QA-S-
L
P
R
I
V
G
T
V
V
G
I
T
-----
V
L
V
V
V
A
L
L----VPV--P
T
A
V
E
L
R
D
W
A
K
S
L
G
A
W
F
----
P
L
A
F
L
--------
L
V
H
T
V
VTV---PPFP
R
-
T
A
F
T
L
A
A
G
L
L
-------
F
G
S
V
V
G
V
F
--------------------
I
A
V
VG
S
T
A
S
A
V
--------
I
A
M
L
L
--
V
RA--TG
W
Q
L
N
S
L
--
V
R
--------
R
--
R
A
--
I
N
R
L
D
E
R
L
R
E------------RG
W
L
A
I
L
S
-
L
R
L----IPVVP
F
A
A
I
NYAA------GAS
G
V
R
I
L
S
-----------
F
A
--
W
---------
A
T
L
A
G
LLPG
T
A
A
V
V
I
L
----GDAF-AGSG
S
P
L
L
I
L
V
S
V
CT----GAL
G
L
T
G
L
-
V
Y
E
I
R
N
Y
R
R
Q
HRRMPGYDDPVREPALI----------------------------------------------------
18
Fugue
89.54
15%
-140
- C2 -
2XM5
10
CLOQ_STRRC
A:
[8-318]
PIDQEFD
C
E
R
F
R
A
D
IRA
T
A
A
A
I
G
A
P
I
A
H
R
L
T
D
T
V
L
E
A
F
R
D
N
F
A
Q
G
A
T
L
--
W
K
T
T
S
Q
P
G
D
Q
L
-
S
Y
--------
R
F
F
S
R
L
K
-
M
-
D
T
V
S
R
A
I
D
A
G
L
L
DAAHP
T
L
A
V
V
D
A
W
----
S
S
L
YG
G
A
P
V
Q
S
G
D
F
D
A
G
R
G
M
A
K
----
T
W
L
Y
F
GGLR----
P
A
E
D
I
L
T
V
---
P
A
L
P
A
-
S
V
Q
A
R
L
K
D
F
L
-------
A
L
G
L
A
H
V
R
--------------------
F
A
A
V
D
W
R
H
H
S
A
--------
N
V
Y
F
R
--
G
K
G
PL
D
T
V
Q
F
A
R
I
--
H
A
L
S
GSTPPA
A
--
H
V
--
V
E
E
V
L
A
Y
M
-
P
------------
E
D
Y
S
V
A
I
T
-
L
D
L
HSGD
I
E
R
V
C
F
Y
A
L
K
V
P
K
------
N
A
L
P
R
I
P
T
R
-----------
I
A
--
R
---------
F
L
E
V
A
P
S
H
D
V
E
E
C
N
V
I
----
G
W
S
F
-
G
R
S
G
-
D
Y
V
K
A
E
R
S
Y
T
----
G
-----
N
M
-
A
E
I
L
A
G
W
N
C
F
F
H
G
E
E
G
R
D
H
D
L
R
A
L
H
Q
H
----------------------------------------------------
17
Fugue
83.18
17%
-114
* C2 *
1QD1
2
FTCD_PIG
A:
[1-325]
-------------------------------------S
Q
L
V
E
C
V
P
N
F
S
EG
K
N
Q
E
V
I
D
A
I
S
R
-
A
V
A
Q
TPGCVL
L
D
V
D
S
G
P
-
S
-
T
N
R
T
V
Y
T
F
V
G
R
P
-----
E
D
V
V
E
G
A
L
----
N
A
A
--
R
A
A
Y
Q
L
I
D
M
S
R
H
H
G
E
H
P
----
R
M
G
A
L
--------
D
V
C
P
F
I
P
V
R
GV
T
M
D
E
C
-
V
R
C
A
Q
A
F
G
Q
R
-------
L
A
E
E
L
G
V
P
--------------------
V
Y
L
Y
G
E
A
A
R
T
A
--------
G
R
Q
S
L
--
P
A
L
--
R
A
G
E
Y
E
A
L
--
P
E
--------
K
L
K
Q
A
--
E
W
A
P
D
F
G
P
S
A
FVPSWG
A
T
V
A
G
A
R
K
F
L
L
A
F
N
-
I
N
L
----
L
S
T
R
E
Q
A
H
R
I
A
L
D
L
REQGG
R
L
K
K
V
Q
A
I
G
-----------
W
Y
--
L
DEKNLAQVS
T
N
L
L
D
F
E
V
T
G
L
H
T
V
F
E
----
E
T
C
R
-
E
A
Q
E
L
S
L
P
V
V
G
S
Q
L
V
----
G
L
V
P
L
K
A
L
-
L
D
A
A
A
F
Y
C
E
K
E
N
L
F
L
L
Q
D
E
H
R
I
R
L
V
V
N
R
L
GLDSL
A
P
F
K
PKERIIEYLV-------------------------------
20
Fugue
79.38
15%
-106
- C2 -
3B21
-
?
A:
[21-212]
----------------------------------------------
N
V
--
N
V
K
K
L
L
E
S
L
N
S
K
S
L
--------
G
D
M
D
K
D
S
-
E
-
L
A
A
T
L
Q
K
M
I
N
------------------------
P
S
G
G
D
----
G
N
C
S
G
C
A
L
----
H
A
C
M
A
--------
M
L
G
Y
G
V
R
E
---
A
P
V
P
N
-
E
I
S
E
Y
M
T
G
F
F
-------
H
R
H
-------------------------
L
E
Q
I
D
S
E
G
------------------
I
V
S
--
H
P
N
E
T
Y
S
K
--
F
R
--------
E
--
R
I
--
A
E
N
I
L
Q
N
-
T
S
------------
K
G
S
V
V
M
I
S
-
I
E
Q
--------------------------------------------
A
--
T
---------
H
W
I
A
G
F
N
D
G
E
K
I
M
F
L
------
D
V
Q
-
T
G
K
G
F
N
L
Y
D
P
V
E
K
S
P
----
D
A
F
V
D
E
N
S
-
S
V
Q
V
I
H
V
S
D
Q
E
F
D
H
Y
A
N
S
S
S
W
K
S
K
R
L
C
----------------------------------------------------
14
Fugue
74.92
21%
-128
- C1 -
1YT3
11
RND_ECOLI
A:
[1-375]
-----------------------------------------
M
N
Y
Q
M
I
---
T
T
D
D
A
L
A
S
L
C
E
-
A
V
--------
R
A
F
P
A
I
A
-
L
-
D
T
E
F
V
R
T
R
T
Y
Y
P
-----
Q
L
G
L
I
Q
L
F
DGE
H
L
A
L
--
I
D
P
L
G
I
T
D
W
-
S
P
L
K
A
I
L
R
DPS
I
T
K
F
L
H
AG
S
E
D
L
E
V
F
L
N
V
F
G
E
---
L
P
Q
P
L
-
I
D
T
Q
I
L
A
A
F
C
GRPMSWG
F
A
S
M
V
E
E
Y
SG
V
T
L
D
KSESRTDWLARPLT
E
R
Q
C
E
Y
A
A
A
D
V
W
Y
L
L
P
I
T
A
K
L
M
V
E
--
T
E
A
--
S
G
W
L
P
A
A
L
D
E
C
R
--------
L
--
M
Q
--
M
R
R
Q
E
V
V
A
P
E
------------
D
A
W
R
D
I
T
N
-
A
W
Q
----
L
R
T
R
Q
L
A
C
L
Q
L
L
A
------
D
W
R
L
R
K
A
R
E
R
DLAVNFVVR
E
E
H
--
L
---------
W
S
V
A
R
Y
M
P
G
S
L
G
E
L
D
S
L
GLS
G
S
E
I
-
R
F
H
G
K
T
L
L
A
L
V
E
K
A
Q
T
LPE
D
A
L
P
Q
P
M
L
N
L
M
D
M
P
G
Y
R
K
A
F
K
A
I
K
S
L
I
T
D
V
S
E
T
H
K
I
SAELLAS
R
R
Q
I
N
Q
L
L
N
W
H
W
KLKPQNNLPELISG
W
R
G
E
L
M
A
E
A
L
H
N
L
L
Q
EYPQ
3
PsiBlast_PDB
58.96
34%
-20
- C3 -
2QF7
3
?
A:
[375-441]
-------------------------------------------------------------------------------------------------------------------------------------------------------------
I
---
P
D
Y
G
R
I
T
A
Y
R
S
A
S
G
---------
F
G
I
R
L
D
G
G
--------------------
T
S
Y
S
G
A
I
I
T
R
Y
--------
Y
D
P
L
L
--
V
K
V
--
T
A
W
A
P
N
P
L
---------------
E
A
--
I
S
R
M
D
R
A
L
R
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
58.30
34%
-18
- C3 -
3TW7
-
?
A:
[375-449]
-------------------------------------------------------------------------------------------------------------------------------------------------------------
I
---
P
D
Y
G
R
I
T
A
Y
R
S
A
S
G
---------
F
G
I
R
L
D
G
G
--------------------
T
S
Y
S
G
A
I
I
T
R
Y
--------
Y
D
P
L
L
--
V
K
V
--
T
A
W
A
P
N
P
L
---------------
E
A
--
I
S
R
M
D
R
A
L
R
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
Fugue
56.32
11%
-49
- C2 -
3ES2
-
?
A:
[145-392]
---------------------------------------------------
L
Q
A
S
L
N
L
L
Q
E
-
D
Q
--------
N
A
G
R
Q
V
Q
M
N
M
L
P
V
T
P
W
S
I
E
G
L
E
-----
F
S
H
R
I
I
P
-------------------
S
L
Y
L
S
G
----------------------
D
F
V
D
Y
---
F
R
V
D
E
-
R
R
V
A
F
Y
L
A
D
V
-------
S
G
H
-----------------------------
G
A
S
S
A
F
V
--------
T
V
L
L
K
F
M
T
T
R
--
L
L
Y
E
S
R
R
F
--
K
P
--------
S
--
E
V
--
L
A
H
I
N
R
G
L
I
N
------------
T
K
L
G
K
H
V
T
M
L
G
G
----
V
I
D
L
E
K
N
S
L
T
Y
S
I
------
G
G
H
L
P
L
P
V
L
-----------
F
V
EG
Q
---------
A
G
Y
L
E
G
R
V
G
L
F
D
D
A
T
Y
----
D
D
R
V
M
E
L
P
P
S
L
S
L
F
S
D
G
I
L
D
----
V
G
A
T
L
K
E
K
-
E
A
S
L
P
E
Q
V
A
A
A
G
G
T
L
D
G
L
R
Q
V
D
D
I
A
L
L
V
L
S
R
N-----------------------------------------------
2
PsiBlast_PDB
54.59
34%
-26
- C3 -
3TW6
-
?
A:
[375-434]
-------------------------------------------------------------------------------------------------------------------------------------------------------------
I
---
P
D
Y
G
R
I
T
A
Y
R
S
A
S
G
---------
F
G
I
R
L
D
G
G
--------------------
T
S
Y
S
G
A
I
I
T
R
Y
--------
Y
D
P
L
L
--
V
K
V
--
T
A
W
A
P
N
P
L
---------------
E
A
--
I
S
R
M
D
R
A
L
R
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
41.21
36%
34
- C3 -
3L0Q
1
?
A:
[235-281]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
-----------
Q
R
--
A
---------
A
S
E
M
G
L
I
P
G
T
A
V
S
V
S
I
----
I
D
A
H
-
A
G
T
-----------
I
----
G
I
L
G
A
S
G
V
-
T
G
E
N
A
N
F
D
R
R
---------------------------------------------------------------------
4
PsiBlast_PDB
40.27
36%
27
- C3 -
3GG4
-
?
A:
[235-281]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
-----------
Q
R
--
A
---------
A
S
E
M
G
L
I
P
G
T
A
V
S
V
S
I
----
I
D
A
H
-
A
G
T
-----------
I
----
G
I
L
G
A
S
G
V
---
E
N
A
N
F
D
R
R
---------------------------------------------------------------------
11
HHSearch
38.87
13%
24
- C3 -
4Z7F
1
?
A:
[60-94]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
-
F
I
P
E
S
L
I
G
M
I
-------
F
G
P
F
W
A
G
I
--------------------
G
T
A
V
A
D
V
V
G
M
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
37.55
16%
29
- C3 -
4HUQ
-
?
S:
[42-72]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
-
F
L
I
V
A
L
I
A
K
W
-------
F
G
P
W
W
G
M
L
--------------------
T
A
A
V
V
D
V
I
G
T
L
--------
M
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
Fugue
37.00
29%
170
* C3 *
2DOH
-
C:
[4-28]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
--
T
A
--------
D
--
A
E
--
L
Q
R
L
K
N
E
R
H
E
------------
E
A
E
L
E
R
L
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
Fugue
35.84
10%
105
- C3 -
5CMZ
-
?
B:
[2-33]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
T
--
W
E
E
--
W
D
K
K
I
E
E
L
--
I
K
--------
K
--
S
E
E
L
I
K
K
I
E
E
Q
I
K
K
------------
Q
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
HHSearch
22.36
9%
59
- C3 -
3QNQ
1
?
A:
[230-251]
---------------------------------------------------------------------------------------------------------------------------------
S
L
W
G
----
A
V
I
A
V
--------
I
L
V
H
V
L
W
A
---
C
G
I
H
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
21.97
5%
272
- C3 -
3RKO
-
?
J:
[147-165]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
L
----
L
A
G
L
V
V
A
F
-
H
V
G
R
E
E
R
A
G
----------------------------------------------------------------------
8
HHSearch
16.81
16%
250
- C4 -
4MA7
1
A:
[3-20]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
A
V
V
G
G
L
--------
G
G
Y
M
L
--
G
S
A
--
M
S
R
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
0.58
19%
599
* C4 *
1TPX
-
PRIO_SHEEP
A:
[127-139]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
L
--------
G
G
Y
M
L
--
G
S
A
--
M
S
R
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------