@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv1761c: (2016-05-04 )
MSDFDTERVSRAVAAALVGPGGVALVVKVFAGLPGVIHTPARRGFFRSNPERIQIGDWRYEVAHDGRLLAAHMVNGIVIAEDALIAEAVGPHLARALGQIVSRYGATVIPNINAAIEVLGTGTDYRF
Atome Classification :
(20 SA)
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10.......---.20.......-------..------30..--.----.---....40.......----.-50...----..-----...---------60....---....----------70..---..-...-.80...---------.....------90....-------..-.-------.-------100.......---110-.-.-------.....-..120.....---------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSD
F
D
T
E
R
V
S
R
A
V
A
A
A
LV---GP-
G
G
V
A
L
V
V
-------
K
V
------
F
AGL--P----G---VIH
T
P
A
RRGFFRS----N-P
E
R
I
Q
----IG-----
D
W
R
---------
Y
E
VAHD---
G
R
L
L
----------
A
A
H
M---VN-
G
I
V
-
I
AE
D
A
L
---------
I
A
E
A
V
------
G
P
H
L
A
R
-------
A
L
-
G
-------
Q
-------
I
V
S
RYG
A
T
VI---P---N-I-------N
A
A
I
E
-
V
L
GTGTDYRF---------------------------------------------------------
9
HHSearch
86.19
98%
-66
- C6 -
2K3M
3
?
A:
[25-151]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
S
D
F
D
T
E
R
V
S
R
A
V
A
A
A
L
V
---
G
P
-
G
G
V
A
L
V
V
-------
K
V
------
C
A
G
L
--
P
----
G
---
V
I
H
T
P
A
R
R
G
F
F
R
C
----
N
-
P
E
R
I
Q
----
I
G
-----
D
W
R
---------
Y
E
V
A
H
D
---
G
R
L
L
----------
A
A
H
M
---
V
N
-
G
I
V
-
I
A
E
D
A
L
---------
I
A
E
A
V
------
G
P
H
L
A
R
-------
A
L
-
G
-------
Q
-------
I
V
C
R
Y
G
A
T
V
I
---
P
---
N
-
I
-------
N
A
A
I
E
-
V
L
G
T
G
T
D
Y
R
F
---------------------------------------------------------
29
Fugue
85.97
97%
-66
- C6 -
2K3M
3
?
A:
[25-151]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
S
D
F
D
T
E
R
V
S
R
A
V
A
A
A
L
V
---
G
P
-
G
G
V
A
L
V
V
-------
K
V
------
C
A
G
L
--
P
----
G
---
V
I
H
T
P
A
R
R
G
F
F
R
C
----
N
-
P
E
R
I
Q
----
I
G
-----
D
W
R
---------
Y
E
V
A
H
D
---
G
R
L
L
----------
A
A
H
M
---
V
N
-
G
I
V
-
I
A
E
D
A
L
---------
I
A
E
A
V
------
G
P
H
L
A
R
-------
A
L
-
G
-------
Q
-------
I
V
C
R
Y
G
A
T
V
I
---
P
---
N
-
I
-------
N
A
A
I
E
-
V
L
G
T
G
T
D
Y
R
F
---------------------------------------------------------
1
PsiBlast_PDB
85.97
97%
-66
- C6 -
2K3M
3
?
A:
[25-151]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
S
D
F
D
T
E
R
V
S
R
A
V
A
A
A
L
V
---
G
P
-
G
G
V
A
L
V
V
-------
K
V
------
C
A
G
L
--
P
----
G
---
V
I
H
T
P
A
R
R
G
F
F
R
C
----
N
-
P
E
R
I
Q
----
I
G
-----
D
W
R
---------
Y
E
V
A
H
D
---
G
R
L
L
----------
A
A
H
M
---
V
N
-
G
I
V
-
I
A
E
D
A
L
---------
I
A
E
A
V
------
G
P
H
L
A
R
-------
A
L
-
G
-------
Q
-------
I
V
C
R
Y
G
A
T
V
I
---
P
---
N
-
I
-------
N
A
A
I
E
-
V
L
G
T
G
T
D
Y
R
F
---------------------------------------------------------
33
Fugue
61.40
13%
-73
* C6 *
1ASH
2
GLB_ASCSU
A:
[1-147]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
N
K
T
R
E
L
C
M
K
S
L
E
H
A
K
V
---
D
T
-
S
N
E
A
R
Q
D
-------
G
I
------
D
L
Y
K
--
H
----
M
---
F
E
N
Y
P
P
L
R
K
Y
F
K
S
REEY
T
-
A
E
D
V
Q
N
DP
F
F
A
-----
K
Q
G
---------
Q
K
I
L
L
A
---
C
H
V
L
----------
C
A
T
Y
DD-
R
E
-
T
F
N
-
A
Y
T
R
E
L
---------
L
D
R
H
A
R
D
HVHM
P
P
E
V
W
T
-------
D
F
-
W
-------
K
-------
L
F
E
E
Y
L
G
K
K
T
TLD
E
---
P
-
T
-------
K
Q
A
W
H
-
E
I
G
R
E
F
A
K
E
I
N
K-------------------------------------------------------
37
Fugue
58.48
16%
-43
- C6 -
2KCK
-
?
A:
[1-112]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
V
D
Q
N
P
E
E
Y
Y
L
E
G
V
L
Q
Y
----
D
A
-
G
N
Y
T
E
S
I
-------
D
L
------
F
E
K
A
--
I
----
Q
---
L
--
D
P
E
E
S
K
Y
W
L
M
----
K
-
G
K
A
L
Y
----
N
L
-----
E
-
R
---------
Y
E
E
A
V
D
---
C
Y
N
Y
----------
V
I
N
V
---
I
E
-
D
--------
E
---------
Y
N
K
D
V
------
W
A
A
K
A
D
-------
A
L
-
R
-------
Y
-------
I
E
G
K
E
V
E
A
E
I
---
A
---
E
-
A
-------
R
A
K
L
E
-----
H
H
H
H
H
H
---------------------------------------------------------
35
Fugue
55.11
14%
-103
* C5 *
4MCJ
1
?
A:
[1-153]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GAQ
S
E
V
V
V
L
Y
PDT
E
N
K
D
L
D
E
A
V
Y
Q
K
I
F
L
A
G
T
---
I
D
M
D
W
Q
K
A
T
C
-------
D
W
------
F
R
A
L
--
P
----
E
G
R
Y
L
L
F
N
P
R
R
D
K
G
L
S
G
----
E
M
S
D
F
E
H
----
Q
V
-----
N
W
E
---------
L
E
H
L
E
K
---
A
D
L
I
I
M
N
I
L
ASSKS
P
I
T
L
---
L
E
M
G
L
F
M
R
S
G
K
L
R
---------
V
I
C
E
P
------
G
F
Y
R
Y
D
-------
N
V
-
R
-------
L
-------
T
C
A
R
Y
G
V
P
L
Y
---
Q
---
N
M
D
-------
D
F
L
K
T
M
R
------------------------------------------------------------------
25
HHSearch
53.54
33%
-74
- C7 -
4UQF
-
GCH1_LISMO
A:
[120-177]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
E
R
I
T
T
T
V
A
E
I
M
M
E
K
L
K
P
-
L
G
V
M
V
I
M
-------
E
A
E
H
MCMT
I
R
G
V
NK
P
----
G
T
--
K
T
I
T
S
A
V
R
G
A
F
K
N
----
D
-
D
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
52.49
26%
-61
- C7 -
1A8R
1
GCH1_ECOLI
A:
[151-208]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
E
R
L
T
Q
Q
I
L
I
A
L
Q
T
L
L
G
T
-
N
N
V
A
V
S
I
-------
D
A
V
H
YCVK
A
R
G
I
RD
A
----
T
S
--
A
T
T
T
T
S
L
G
G
L
F
K
S
----
S
-
Q
N
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
Fugue
50.57
19%
-52
- C5 -
1K3E
-
CEST_ECO57
A:
[1-146]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
S
S
-
R
S
E
L
L
L
E
K
F
A
E
K
I
----
G
I
-
G
S
I
S
F
N
E
-------
N
R
------
L
C
----
S
----
F
---
A
I
D
E
I
Y
Y
I
S
L
S
D
A
----
N
-
D
E
Y
M
M
----
I
Y
-----
G
V
C
---------
G
K
F
P
T
D
---
N
S
N
F
----------
A
L
E
I
---
L
N
-------
A
N
L
W
---------
F
A
E
N
G
------
G
P
Y
L
C
Y
EAGAQSL
L
L
-
A
-------
L
-------
R
F
P
L
D
D
A
T
P
E
---
K
---
L
-
E
-------
N
E
I
E
V
-
V
V
K
S
M
E
N
L
Y
L
V
L
H
N
Q
GITLK
I
E
E
I
S
S-----------------------------------------
13
HHSearch
50.46
30%
-74
- C7 -
1IS8
-
GCH1_RAT
A:
[162-220]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
E
R
L
T
K
Q
I
A
V
A
I
T
E
A
L
Q
P
-
A
G
V
G
V
V
I
-------
E
A
T
H
M
C
M
V
M
R
G
-K-
M
----
N
S
--
K
T
V
T
S
T
M
L
G
V
F
R
E
----
D
-
P
K
T
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
Fugue
50.13
25%
-88
- C4 -
4R6H
5
MSME_BACSU
A:
[28-421]
ADTA
K
K
T
L
T
I
Y
S
TMST
D
S
E
R
D
T
F
R
K
L
A
A
A
F
E
K
E
H
SD
I
H
V
S
L
H
FPGND
Y
E
N
M
M
R
V
R
M
A
A
NDLPD
L
F
D
THGWGKIRYGEYTADLRDMKWTQDLDPNLNSILKNKSGKVYAYPI
N
Q
A
K
D
G
L
AYN
R
N
I
L
D
R
Y
GIAPPET
M
D
D
F
I
K
A
L
R
T
I
K
E
K
S
K
GSIVPFWFAGYD
K
S
S
F
A
Q
Y
Y
D
Q
F
A
T
P
L
LITDPAHNE
K
K
Q
L
I
N
GTFQWSKF
T
Y
L
S
E
I
L
K
Q
M
Q
K
E
K
L
I
N
I
D
A
V
T
A
K
K
S
Q
L
I
E
L
M
---
A
Q
-
N
K
I
A
F
T
M
QGGT
L
G
Q
D
V
------
A
Q
I
N
--
P
N
V
K
V
G
---
I
I
P
T
P
A
----
I
H
P
----
G
-
D
D
P
I
W
----
I
G
-----
G
E
R
---------
Y
----------
T
L
----------
A
A
W
K
---
D
S
-
P
Q
L
-
K
E
A
K
D
F
---------
I
A
F
M
A
------
R
P
A
N
A
K
-------
Q
M
-
A
-------
E
-------
A
T
S
L
P
S
G
--
L
---
T
---
N
-
V
-------
K
A
D
I
F
-
Y
---
A
N
D
Y
E
Y
Y
QD
V
K
V
E
P
YFDRLYLPNG
M
W
D
V
L
G
T
V
G
Q
E
L
A
A
DILA
P
Q
D
I
S
Q
K
L
G
R
E
Y
K
R
L
R
E
Q
S
E
T
36
Fugue
49.09
13%
-59
- C3 -
2H1T
4
?
A:
[3-188]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SR
D
R
L
Y
T
W
A
G
L
W
R
S
P
S
S
S
W
E
A
L
R
L
E
D
D
Q
A
E
S
Q
L
R
A
P
D
E
R
---
S
G
-
L
P
Y
Q
L
D
Y
-------
R
L
------
R
W
D
A
--
D
----
W
---
H
L
R
E
A
V
F
H
V
E
S
E
T
----
G
-
V
R
K
L
H
----
L
L
A
DGRG
H
W
Q
D
GDGEALPA
F
D
G
C
L
D
---
I
D
I
W
----------
P
S
P
F
---
T
N
-
T
F
P
-
I
R
R
L
G
L
ADG
Q
R
A
E
I
R
A
L
Y
I
E
------
A
P
A
L
E
P
-------
R
S
M
R
-------
Q
-------
A
Y
T
R
L
D
A
S
H
Y
---
L
---
Y
-
E
N
LEGSA
F
K
A
V
L
L
-
V
D
E
Q
G
L
V
I
D
Y
PGLFQRL--------------------------------------------------
17
HHSearch
44.91
17%
-99
- C7 -
2K4V
-
?
A:
[26-83]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
I
R
---------
Y
E
V
R
Q
N
AES
G
A
Y
V
----------
H
F
D
M
D
G
E
I
D
-
G
K
P
-
F
S
D
S
F
E
---------
L
P
R
D
T
------
A
F
N
F
A
S
-------
D
A
-
T
-------
R
-------
V
A
Q
K
H
G
L
H
P
-------------------------------------------------------------------------------------------
11
HHSearch
44.16
17%
-89
- C7 -
2RHF
1
?
A:
[11-76]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
R
-----
E
L
R
---------
R
E
L
M
K
E
---
T
G
Y
S
----------
A
F
V
V
---
F
T
-
N
A
T
-
L
E
A
L
A
A
-------------
R
------
Q
P
R
T
L
A
-------
E
L
-
A
E
VPGLG
E
K
-------
R
I
E
A
Y
G
E
R
I
L
---
D
---
A
-
I
-------
N
T
V
L
D
--------------------------------------------------------------------
5
PsiBlast_PDB
43.53
34%
-82
- C11 -
2JKT
1
AP2A2_MOUSE
A:
[175-211]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Y
R
T
----
S
-
P
D
L
V
P
----
M
G
-----
D
W
T
---------
S
R
V
V
H
-----
L
L
N
----------
D
Q
H
L
------
G
V
V
-
T
A
A
T
S
L
---------
I
----------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
41.52
34%
-83
* C11 *
2XA7
-
AP2A2_RAT
A:
[175-211]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Y
R
T
----
S
-
P
D
L
V
P
----
M
G
-----
D
W
T
---------
S
R
V
V
H
-----
L
L
N
----------
D
Q
H
L
------
G
V
V
-
T
A
A
T
S
L
---------
I
----------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
41.51
34%
-86
- C11 -
4NEE
-
AP2A2_RAT
G:
[175-211]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Y
R
T
----
S
-
P
D
L
V
P
----
M
G
-----
D
W
T
---------
S
R
V
V
H
-----
L
L
N
----------
D
Q
H
L
------
G
V
V
-
T
A
A
T
S
L
---------
I
----------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
41.49
34%
-80
- C11 -
2JKR
1
AP2A2_MOUSE
A:
[175-211]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Y
R
T
----
S
-
P
D
L
V
P
----
M
G
-----
D
W
T
---------
S
R
V
V
H
-----
L
L
N
----------
D
Q
H
L
------
G
V
V
-
T
A
A
T
S
L
---------
I
----------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
41.15
31%
-99
* C9 *
3E18
3
?
A:
[161-228]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
-----
D
W
R
---------
H
L
K
A
H
G
---
G
G
M
V
LD
W
-------
G
V
H
L
---
L
D
-
Q
L
L
-
F
L
V
D
S
N
---------
V
-
K
S
V
------
S
A
N
L
S
F
-------
A
L
-
G
-------
D
-------
E
V
D
D
G
F
V
T
F
I
---
T
F
EN
G
-
I
-------
T
A
Q
I
E
-
V
------------------------------------------------------------------
14
HHSearch
40.95
18%
-78
- C7 -
1WUD
-
RECQ_ECOLI
A:
[539-606]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
R
-----
K
L
R
---------
K
S
I
A
D
E
---
S
N
V
P
----------
P
Y
V
V
---
F
N
-
D
A
T
-
L
I
E
M
A
E
-------------
Q
------
M
P
I
T
A
S
-------
E
M
-
L
-------
S
VNGVG
M
R
K
L
E
R
F
G
K
P
F
M
---
A
---
L
-
I
-------
R
A
H
V
D
-
G
D
-----------------------------------------------------------------