@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv3674c: (2016-05-22 )
MPGRWSAETRLALVRRARRMNRALAQAFPHVYCELDFTTPLELAVATILSAQSTDKRVNLTTPALFARYRTARDYAQADRTELESLIRPTGFYRNKAASLIGLGQALVERFGGEVPATMDKLVTLPGVGRKTANVILGNAFGIPGITVDTHFGRLVRRWRWTTAEDPVKVEQAVGELIERKEWTLLSHRVIFHGRRVCHARRPACGVCVLAKDCPSFGLGPTEPLLAAPLVQGPETDHLLALAGL
Atome Classification :
(20 SA)
.........10........20........30.----..-.--------..---..40........50........60........70........80........90-.........100.......110.--------------......120..-.....130.......140.......150.......160---.....-----...-.------170.......180-.--.......190.......200.......210.......-220.......230.......240...----------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MPGRWS
A
E
T
R
L
A
L
V
R
R
A
R
R
M
N
R
A
L
A
Q
AFP
H
V
Y
----
C
E
-L--------DF---TT
P
L
E
L
A
V
A
T
I
L
SAQSTD
K
R
V
NLT
T
P
A
L
F
A
R
Y
R
T
A
R
D
Y
A
Q
A
D
R
T
E
L
E
S
L
IRPT--GFY
R
N
K
A
A
S
L
I
G
L
G
Q
A
L
V
E
R
FGG--------------EVP
A
T
M
D
K
L
VT-LPGVGR
K
T
A
N
V
I
L
GNAFGIP
G
I
T
V
D
T
H
F
G
R
L
V
R
R
WR-----WTTAE-----DP
V
-
K
------
V
E
Q
A
V
G
E
L
I
E
RK--
E
--
W
T
L
L
S
H
R
V
I
FHGRRVCHARRPAC
G
V
C
V
LAKDCPSFGL-GPTEPLLAAPLVQGPETD
H
L
L
ALAGL----------------------------------------------------------------------------------------------------------
79
HHSearch
98.12
40%
-105
- C6 -
1ORN
5
?
A:
[5-217]
-----------
L
T
K
Q
Q
I
R
Y
C
L
D
E
M
A
K
M
F
P
D
A
H
----
C
E
-
L
--------
V
H
---
R
N
P
F
E
L
L
I
A
V
V
L
S
A
Q
C
T
D
A
L
V
N
K
V
T
K
R
L
F
E
K
Y
R
T
P
H
D
Y
I
A
V
P
L
E
E
L
E
Q
D
I
R
S
I
--
G
L
Y
R
N
K
A
R
N
I
Q
K
L
C
A
M
L
I
D
K
Y
N
G
--------------
E
V
P
R
D
R
D
E
L
M
K
-
L
P
G
V
G
R
K
T
A
N
V
V
V
S
V
A
F
G
V
P
A
I
A
V
D
T
H
V
E
R
V
S
K
R
L
G
-----
F
C
R
W
D
D----
S
V
L
-
E
------
V
E
K
T
L
M
K
I
I
P
K
E
--
E
--
W
S
I
T
H
H
R
M
I
F
F
G
R
Y
H
C
K
A
Q
S
P
Q
C
P
S
C
P
L
L
H
L
C
R
E
G
K
K
-
R
M
R
K
--------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
94.29
45%
-110
- C6 -
1P59
4
?
A:
[17-208]
-----------------------
M
A
K
M
F
P
D
A
H
----
C
E
-
L
--------
V
H
---
R
N
P
F
E
L
L
I
A
V
V
L
S
A
Q
C
T
D
A
L
V
N
K
V
T
K
R
L
F
E
K
Y
R
T
P
H
D
Y
I
A
V
P
L
E
E
L
E
Q
D
I
R
S
I
--
G
L
Y
R
N
K
A
R
N
I
Q
K
L
C
A
M
L
I
D
K
Y
N
G
--------------
E
V
P
R
D
R
D
E
L
M
K
-
L
P
G
V
G
R
K
T
A
N
V
V
V
S
T
A
F
G
V
P
A
I
A
V
D
T
H
V
E
R
V
S
K
R
L
G
-----
F
C
R
W
D
-----
D
S
V
L
E
------
V
E
K
T
L
M
K
I
I
P
K
E
--
E
--
W
S
I
T
H
H
R
M
I
F
F
G
R
Y
H
C
K
A
Q
S
P
Q
C
P
S
C
P
L
L
H
L
C
------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
94.28
45%
-115
- C6 -
1ORP
4
?
A:
[17-208]
-----------------------
M
A
K
M
F
P
D
A
H
----
C
E
-
L
--------
V
H
---
R
N
P
F
E
L
L
I
A
V
V
L
S
A
Q
C
T
D
A
L
V
N
K
V
T
K
R
L
F
E
K
Y
R
T
P
H
D
Y
I
A
V
P
L
E
E
L
E
Q
D
I
R
S
I
--
G
L
Y
R
N
K
A
R
N
I
Q
K
L
C
A
M
L
I
D
K
Y
N
G
--------------
E
V
P
R
D
R
D
E
L
M
K
-
L
P
G
V
G
R
K
T
A
N
V
V
V
S
V
A
F
G
V
P
A
I
A
V
D
T
H
V
E
R
V
S
K
R
L
G
-----
F
C
R
W
D
-----
D
S
V
L
E
------
V
E
K
T
L
M
K
I
I
P
K
E
--
E
--
W
S
I
T
H
H
R
M
I
F
F
G
R
Y
H
C
K
A
Q
S
P
Q
C
P
S
C
P
L
L
H
L
C
------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
94.07
45%
-111
- C6 -
1ORN
5
?
A:
[17-208]
-----------------------
M
A
K
M
F
P
D
A
H
----
C
E
-
L
--------
V
H
---
R
N
P
F
E
L
L
I
A
V
V
L
S
A
Q
C
T
D
A
L
V
N
K
V
T
K
R
L
F
E
K
Y
R
T
P
H
D
Y
I
A
V
P
L
E
E
L
E
Q
D
I
R
S
I
--
G
L
Y
R
N
K
A
R
N
I
Q
K
L
C
A
M
L
I
D
K
Y
N
G
--------------
E
V
P
R
D
R
D
E
L
M
K
-
L
P
G
V
G
R
K
T
A
N
V
V
V
S
V
A
F
G
V
P
A
I
A
V
D
T
H
V
E
R
V
S
K
R
L
G
-----
F
C
R
W
D
-----
D
S
V
L
E
------
V
E
K
T
L
M
K
I
I
P
K
E
--
E
--
W
S
I
T
H
H
R
M
I
F
F
G
R
Y
H
C
K
A
Q
S
P
Q
C
P
S
C
P
L
L
H
L
C
------------------------------------------------------------------------------------------------------------------------------------------
78
HHSearch
90.48
35%
-113
- C6 -
2ABK
1
END3_ECOLI
A:
[4-209]
--------------
A
K
R
L
E
I
L
T
R
L
R
E
N
N
P
H
P
T
----
T
E
-
L
--------
N
F
---
S
S
P
F
E
L
L
I
A
V
L
L
S
A
Q
A
T
D
V
S
V
N
K
A
T
A
K
L
Y
P
V
A
N
T
P
A
A
M
L
E
L
G
V
E
G
V
K
T
Y
I
K
T
I
--
G
L
Y
N
S
K
A
E
N
I
I
K
T
C
R
I
L
L
E
Q
H
N
G
--------------
E
V
P
E
D
R
A
A
L
E
A
-
L
P
G
V
G
R
K
T
A
N
V
V
L
N
T
A
F
G
W
P
T
I
A
V
D
T
H
I
F
R
V
C
N
R
T
Q
-----
F
A
P
G
K
-----
N
V
E
-
Q
------
V
E
E
K
L
L
K
V
V
P
A
E
--
F
--
K
V
D
C
H
H
W
L
I
L
H
G
R
Y
T
C
I
A
R
K
P
R
C
G
S
C
I
I
E
D
L
C
E
Y
K
E
K
-
V
-----------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
90.05
37%
-111
- C6 -
2ABK
1
END3_ECOLI
A:
[6-203]
---------
R
L
E
I
L
T
R
L
R
E
N
N
-------
P
H
P
T
----
T
E
-
L
--------
N
F
---
S
S
P
F
E
L
L
I
A
V
L
L
S
A
Q
A
T
D
V
S
V
N
K
A
T
A
K
L
Y
P
V
A
N
T
P
A
A
M
L
E
L
G
V
E
G
V
K
T
Y
I
K
T
I
--
G
L
Y
N
S
K
A
E
N
I
I
K
T
C
R
I
L
L
E
Q
H
N
G
--------------
E
V
P
E
D
R
A
A
L
E
A
-
L
P
G
V
G
R
K
T
A
N
V
V
L
N
T
A
F
G
W
P
T
I
A
V
D
T
H
I
F
R
V
C
N
R
T
Q
-----
F
A
P
G
K
-----
N
V
E
-
Q
------
V
E
E
K
L
L
K
V
V
P
A
E
--
F
--
K
V
D
C
H
H
W
L
I
L
H
G
R
Y
T
C
I
A
R
K
P
R
C
G
S
C
I
I
E
D
L
C
------------------------------------------------------------------------------------------------------------------------------------------
84
HHSearch
85.88
26%
-106
- C6 -
4UOB
8
?
A:
[37-265]
-------------
P
V
W
F
G
E
Y
L
S
R
L
R
D
T
Y
A
P
E
L
----
P
P
P
R
--------
Q
F
---
P
D
P
L
G
G
L
I
R
T
I
L
S
Q
Q
N
T
R
R
V
A
Q
R
Q
W
E
V
L
T
A
T
Y
P
Q
W
E
A
A
L
L
D
G
P
D
G
I
E
A
T
L
K
S
A
GG
G
L
S
R
M
K
A
D
Y
I
Y
G
I
L
A
H
L
Q
E
H
H
G
G
LSL
R
F
L
R
E
FPHT
P
E
G
H
E
Q
A
R
Q
A
L
A
A
-
L
P
G
V
G
H
K
T
V
A
L
V
L
L
F
D
L
R
R
P
A
M
P
V
D
G
N
M
E
R
A
A
K
R
L
E
-----
L
V
P
A
A
W----
N
S
H
-
K
------
V
E
R
W
Y
A
E
V
M
P
A
D
--
W
E
T
R
F
A
L
H
I
S
G
V
R
H
G
R
D
T
C
R
S
K
H
P
L
C
P
Q
C
P
L
R
E
F
C
P
S
A
S
I
-
F
E
L
---------------------------------------------------------------------------------------------------------------------------------
71
Fugue
83.89
25%
-97
- C6 -
1RRQ
4
MUTY_GEOSE
A:
[12-362]
---------------
P
A
R
E
F
Q
R
D
L
L
D
W
F
A
R
E
R
----
R
D
-
L
--------
P
W
RKD
R
D
P
Y
K
V
W
V
S
E
V
M
L
Q
Q
T
R
V
E
T
V
I
P
Y
F
E
Q
F
I
D
R
F
P
T
L
E
A
L
A
D
A
D
E
D
E
V
L
K
A
W
E
G
L
--
G
Y
Y
-
S
R
V
R
N
L
H
A
A
V
K
E
V
K
T
R
Y
G
G
--------------
K
V
P
D
D
P
D
E
F
S
R
-
L
K
G
V
G
P
Y
T
V
G
A
V
L
S
L
A
Y
G
V
P
E
P
A
V
N
G
N
V
M
R
V
L
S
R
L
F
LVTDD
I
A
K
C
S
-----
T
R
K
-
R
------
F
E
Q
I
V
R
E
I
M
A
Y
E
--
N
--
P
G
A
F
N
E
A
L
I
E
L
G
A
L
V
C
T
P
R
R
P
S
C
L
L
C
P
V
Q
A
Y
C
Q
A
F
A
E
-
G
V
A
E
E
L
P
V
K
M
V
K
Q
V
P
L
A
V
A
V
L
A
D
D
E
G
R
V
L
I
R
K
R
D
STGLLAN
L
W
E
F
PSCETDGADG
K
E
K
L
E
Q
M
VGL
Q
V
E
L
T
E
PI
V
S
F
E
H
A
F
SHLVWQ
L
T
V
F
P
G
R
L
V
H
G
G
P
V
E
E
P
Y
R
L
A
P
EDELKA
Y
A
F
P
V
S
H
Q
R
V
W
R
E
Y
K
E
W
A
85
HHSearch
81.34
26%
-93
- C6 -
3FSP
4
MUTY_GEOSE
A:
[11-225]
--------------
F
P
A
R
E
F
Q
R
D
L
L
D
W
F
A
R
E
R
RDL-
P
W
-
R
--------
K
D
---
R
D
P
Y
K
V
W
V
S
E
V
M
L
Q
Q
T
R
V
E
T
V
I
P
Y
F
E
Q
F
I
D
R
F
P
T
L
E
A
L
A
D
A
D
E
D
E
V
L
K
A
W
E
G
L
--
G
Y
Y
S
-
R
V
R
N
L
H
A
A
V
K
E
V
K
T
R
Y
G
G
--------------
K
V
P
D
D
P
D
E
F
S
R
-
L
K
G
V
G
P
Y
T
V
G
A
V
L
S
L
A
Y
G
V
P
E
P
A
V
D
G
N
V
M
R
V
L
S
R
L
F
-----
L
V
T
D
D
IAK
P
S
T
R
K
-
R
------
F
E
Q
I
V
R
E
I
M
A
Y
E
--
N
--
P
G
A
F
N
E
A
L
I
E
L
G
A
L
V
C
T
P
R
R
P
S
C
L
L
C
P
V
Q
A
Y
C
Q
A
F
A
E
-
G
V
A
---------------------------------------------------------------------------------------------------------------------------------
80
HHSearch
81.17
24%
-103
- C6 -
4UNF
5
?
A:
[33-253]
----------------
L
A
W
V
K
E
R
L
H
E
E
Y
G
D
Q
D
----
P
--
T
--------
P
R
---
R
D
P
M
H
E
L
I
S
T
I
L
S
Q
R
T
T
H
A
D
E
E
A
A
Y
Q
E
L
R
-
T
L
G
D
W
D
A
I
T
L
A
P
T
D
A
V
A
H
A
I
R
R
S
--
N
Y
P
E
S
K
A
P
R
I
Q
E
T
L
R
R
I
K
A
A
P
G
G
YDLDFLRDL-----
P
V
K
D
A
L
K
W
L
T
D
-
L
P
G
V
G
V
K
T
A
S
L
V
L
L
F
N
Y
A
R
P
V
F
P
V
D
T
H
V
H
R
V
S
T
R
V
G
-----
V
I
P
R
M
-----
G
E
Q
-
A
------
A
H
R
A
L
L
A
L
L
P
P
D
P
P
Y
--
L
Y
E
L
H
I
N
F
L
S
H
G
R
Q
V
C
T
W
T
R
P
K
C
G
K
C
I
L
R
E
R
C
D
A
Y
A
L
Y
G
D
K
V
P
S
F
S
----------------------------------------------------------------------------------------------------------------------------
82
HHSearch
79.91
23%
-97
- C6 -
3N5N
1
MUTYH_HUMAN
X:
[13-244]
--------------
A
E
V
T
A
F
R
G
S
L
L
S
W
Y
D
Q
E
K
RDL-
P
W
-
R
RRAEDEMD
L
D
---
R
R
A
Y
A
V
W
V
S
E
V
M
L
Q
Q
T
Q
V
A
T
V
I
N
Y
Y
T
G
W
M
Q
K
W
P
T
L
Q
D
L
A
S
A
S
L
E
E
V
N
Q
L
W
A
G
L
--
G
Y
Y
S
-
R
G
R
R
L
Q
E
G
A
R
K
V
V
E
E
L
G
G
--------------
H
M
P
R
T
A
E
T
L
Q
Q
L
L
P
G
V
G
R
Y
T
A
G
A
I
A
S
I
A
F
G
Q
A
T
G
V
V
D
G
N
V
A
R
V
L
C
R
V
R
-----
A
I
G
A
D
PSSTL
V
S
Q
-
Q
------
L
W
G
L
A
Q
Q
L
V
D
P
A
--
R
--
P
G
D
F
N
Q
A
A
M
E
L
G
A
T
V
C
T
P
Q
R
P
L
C
S
Q
C
P
V
E
S
L
C
R
A
R
Q
R
-
V
E
Q
E
Q
L
------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
79.35
27%
-104
- C6 -
1RRQ
4
MUTY_GEOSE
A:
[39-236]
-------------------------------------------------------
P
Y
K
V
W
V
S
E
V
M
L
Q
Q
T
R
V
E
T
V
I
P
Y
F
E
Q
F
I
D
R
F
P
T
L
E
A
L
A
D
A
D
E
D
E
V
L
K
A
W
E
G
L
--
G
Y
Y
-
S
R
V
R
N
L
H
A
A
V
K
E
V
K
T
R
Y
G
G
--------------
K
V
P
D
D
P
D
E
F
S
R
-
L
K
G
V
G
P
Y
T
V
G
A
V
L
S
L
A
Y
G
V
P
E
P
A
V
N
G
N
V
M
R
V
L
S
R
L
F
-----
L
V
T
-
D
-----
D
I
A
-
K
CS
T
R
K
R
F
E
Q
I
V
R
E
I
M
A
Y
E
--
N
--
P
G
A
F
N
E
A
L
I
E
L
G
A
L
V
C
T
P
R
R
P
S
C
L
L
C
P
V
Q
A
Y
C
Q
A
F
A
E
-
G
V
A
E
E
L
------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
78.34
27%
-102
- C6 -
4YOQ
5
MUTY_GEOSE
A:
[39-236]
-------------------------------------------------------
P
Y
K
V
W
V
S
E
V
M
L
Q
Q
T
R
V
E
T
V
I
P
Y
F
E
Q
F
I
D
R
F
P
T
L
E
A
L
A
D
A
D
E
D
E
V
L
K
A
W
E
G
L
--
G
Y
Y
-
S
R
V
R
N
L
H
A
A
V
K
E
V
K
T
R
Y
G
G
--------------
K
V
P
D
D
P
D
E
F
S
R
-
L
K
G
V
G
P
Y
T
V
G
A
V
L
S
L
A
Y
G
V
P
E
P
A
V
D
G
N
V
M
R
V
L
S
R
L
F
-----
L
V
T
-
D
-----
D
I
A
-
K
CS
T
R
K
R
F
E
Q
I
V
R
E
I
M
A
Y
E
--
N
--
P
G
A
F
N
E
A
L
I
E
L
G
A
L
V
C
T
P
R
R
P
S
C
L
L
C
P
V
Q
A
Y
C
Q
A
F
A
E
-
G
V
A
E
E
L
------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
78.09
27%
-103
- C6 -
1VRL
5
MUTY_GEOSE
A:
[39-234]
-------------------------------------------------------
P
Y
K
V
W
V
S
E
V
M
L
Q
Q
T
R
V
E
T
V
I
P
Y
F
E
Q
F
I
D
R
F
P
T
L
E
A
L
A
D
A
D
E
D
E
V
L
K
A
W
E
G
L
--
G
Y
Y
-
S
R
V
R
N
L
H
A
A
V
K
E
V
K
T
R
Y
G
G
--------------
K
V
P
D
D
P
D
E
F
S
R
-
L
K
G
V
G
P
Y
T
V
G
A
V
L
S
L
A
Y
G
V
P
E
P
A
V
N
G
N
V
M
R
V
L
S
R
L
F
-----
L
V
T
-
D
-----
D
I
A
-
K
P
S
T
R
K
R
F
E
Q
I
V
R
E
I
M
A
Y
E
--
N
--
P
G
A
F
N
E
A
L
I
E
L
G
A
L
V
C
T
P
R
R
P
S
C
L
L
C
P
V
Q
A
Y
C
Q
A
F
A
E
-
G
V
A
E
E
L
------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
77.17
27%
-102
- C6 -
3FSP
4
MUTY_GEOSE
A:
[39-228]
-------------------------------------------------------
P
Y
K
V
W
V
S
E
V
M
L
Q
Q
T
R
V
E
T
V
I
P
Y
F
E
Q
F
I
D
R
F
P
T
L
E
A
L
A
D
A
D
E
D
E
V
L
K
A
W
E
G
L
--
G
Y
Y
-
S
R
V
R
N
L
H
A
A
V
K
E
V
K
T
R
Y
G
G
--------------
K
V
P
D
D
P
D
E
F
S
R
-
L
K
G
V
G
P
Y
T
V
G
A
V
L
S
L
A
Y
G
V
P
E
P
A
V
D
G
N
V
M
R
V
L
S
R
L
F
-----
L
V
T
-
D
-----
D
I
A
-
K
P
S
T
R
K
R
F
E
Q
I
V
R
E
I
M
A
Y
E
--
N
--
P
G
A
F
N
E
A
L
I
E
L
G
A
L
V
C
T
P
R
R
P
S
C
L
L
C
P
V
Q
A
Y
C
Q
A
F
A
E
-
G
V
A
E
E
L
------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
77.11
27%
-103
- C6 -
4YPH
4
MUTY_GEOSE
A:
[39-236]
-------------------------------------------------------
P
Y
K
V
W
V
S
E
V
M
L
Q
Q
T
R
V
E
T
V
I
P
Y
F
E
Q
F
I
D
R
F
P
T
L
E
A
L
A
D
A
D
E
D
E
V
L
K
A
W
E
G
L
--
G
Y
Y
-
S
R
V
R
N
L
H
A
A
V
K
E
V
K
T
R
Y
G
G
--------------
K
V
P
D
D
P
D
E
F
S
R
-
L
K
G
V
G
P
Y
T
V
G
A
V
L
S
L
A
Y
G
V
P
E
P
A
V
D
G
N
V
M
R
V
L
S
R
L
F
-----
L
V
T
-
D
-----
D
I
A
-
K
C
S
T
R
K
R
F
E
Q
I
V
R
E
I
M
A
Y
E
--
N
--
P
G
A
F
N
E
A
L
I
E
L
G
A
L
V
C
T
P
R
R
P
S
C
L
L
C
P
V
Q
A
Y
C
Q
A
F
A
E
-
G
V
A
E
E
L
------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
76.69
27%
-100
- C6 -
1RRS
4
MUTY_GEOSE
A:
[39-235]
-------------------------------------------------------
P
Y
K
V
W
V
S
E
V
M
L
Q
Q
T
R
V
E
T
V
I
P
Y
F
E
Q
F
I
D
R
F
P
T
L
E
A
L
A
D
A
D
E
D
E
V
L
K
A
W
E
G
L
--
G
Y
Y
-
S
R
V
R
N
L
H
A
A
V
K
E
V
K
T
R
Y
G
G
--------------
K
V
P
D
D
P
D
E
F
S
R
-
L
K
G
V
G
P
Y
T
V
G
A
V
L
S
L
A
Y
G
V
P
E
P
A
V
N
G
N
V
M
R
V
L
S
R
L
F
-----
L
V
T
-
D
-----
D
I
A
-
K
P
S
T
R
K
R
F
E
Q
I
V
R
E
I
M
A
Y
E
--
N
--
P
G
A
F
N
E
A
L
I
E
L
G
A
L
V
C
T
P
R
R
P
S
C
L
L
C
P
V
Q
A
Y
C
Q
A
F
A
E
-
G
V
A
E
E
L
------------------------------------------------------------------------------------------------------------------------------
81
HHSearch
76.65
21%
-103
- C6 -
1KG2
6
MUTY_ECOLI
A:
[3-216]
----------------
A
S
Q
F
S
A
Q
V
L
D
W
Y
D
K
Y
G
RKTL
P
W
-
Q
--------
I
D
---
K
T
P
Y
K
V
W
L
S
E
V
M
L
Q
Q
T
Q
V
A
T
V
I
P
Y
F
E
R
F
M
A
R
F
P
T
V
T
D
L
A
N
A
P
L
D
E
V
L
H
L
W
T
G
L
--
G
Y
Y
-
A
R
A
R
N
L
H
K
A
A
Q
Q
V
A
T
L
H
G
G
--------------
K
F
P
E
T
F
E
E
V
A
A
-
L
P
G
V
G
R
S
T
A
G
A
I
L
S
L
S
L
G
K
H
F
P
I
L
D
G
N
V
K
R
V
L
A
R
C
Y
-----
A
V
S
G
W
P----
G
K
K
-
E
V
E
N
K
--
L
W
S
L
S
E
Q
V
T
P
A
V
--
G
--
V
E
R
F
N
Q
A
M
M
D
L
G
A
M
I
C
T
R
S
K
P
K
C
S
L
C
P
L
Q
N
G
C
I
A
A
A
N
-
N
S
W
---------------------------------------------------------------------------------------------------------------------------------
83
HHSearch
76.35
20%
-101
- C6 -
1KEA
8
GTMR_METTF
A:
[6-219]
-------------
N
K
K
R
K
V
F
V
S
T
I
L
T
F
W
N
T
D
R
R
D
F
-
P
W
-
R
--------
H
T
---
R
D
P
Y
V
I
L
I
T
E
I
L
L
R
R
T
T
A
G
H
V
K
K
I
Y
D
K
F
F
V
K
Y
K
C
F
E
D
I
L
K
T
P
K
S
E
I
A
K
D
I
K
E
I
--
G
L
S
N
Q
R
A
E
Q
L
K
E
L
A
R
V
V
I
N
D
Y
G
G
--------------
R
V
P
R
N
R
K
A
I
L
D
-
L
P
G
V
G
K
Y
T
C
A
A
V
M
C
L
A
F
G
K
K
A
A
M
V
D
A
N
F
V
R
V
I
N
R
Y
F
-----
G
G
S
Y
E
NLNY-
N
H
K
-
A
------
L
W
E
L
A
E
T
L
V
P
G
G
--
K
--
C
R
D
F
N
L
G
L
M
D
F
S
A
I
I
C
A
P
R
K
P
K
C
E
K
C
G
M
S
K
L
C
S
Y
Y
E
K
-
C
-----------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
75.89
27%
-95
- C6 -
4YPR
3
MUTY_GEOSE
A:
[39-228]
-------------------------------------------------------
P
Y
K
V
W
V
S
E
V
M
L
Q
Q
T
R
V
E
T
V
I
P
Y
F
E
Q
F
I
D
R
F
P
T
L
E
A
L
A
D
A
D
E
D
E
V
L
K
A
W
E
G
L
--
G
Y
Y
-
S
R
V
R
N
L
H
A
A
V
K
E
V
K
T
R
Y
G
G
--------------
K
V
P
D
D
P
D
E
F
S
R
-
L
K
G
V
G
P
Y
T
V
G
A
V
L
S
L
A
Y
G
V
P
E
P
A
V
N
G
N
V
M
R
V
L
S
R
L
F
-----
L
V
T
-
D
-----
D
I
A
-
K
C
S
T
R
K
R
F
E
Q
I
V
R
E
I
M
A
Y
E
--
N
--
P
G
A
F
N
E
A
L
I
E
L
G
A
L
V
C
T
P
R
R
P
S
C
L
L
C
P
V
Q
A
Y
C
Q
A
F
A
E
-
G
V
A
E
E
L
------------------------------------------------------------------------------------------------------------------------------