@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA4372: (2016-02-26 )
MFRPRLLLTSLAIALGACSPQDPQAVTSAALAQQVILPTYSRWVEADQALASSALAYCQGKEDLAKARDAFHAAQKAWAELQPLLIGPLAEGNRAWQVQFWPDKKDLVGRQVEQLLKNNPQVDAAALAKASVVVQGLSAYEYILFDSKIDLADAATKARYCPLLEAIGTHQQQLAQDILARWKNDGGMLTQMSKFPNDRYADAHEAIAELLRVQVTALDMLKKKLGTPLGRQSKGIPQPYQAEAWRSNASLASLDASLSGAQALWEGIDGKGLKTLLPAEQKDLAGKIDAAYADSHAKLAALEQKPLSELLASEDGRNQLNALYDSLNVVHRLHEGDLARALGVQLGFNANDGD
Atome Classification :
(20 SA)
----------------------------------------------------------------------------...-------......10....-------------....20..---..--....30...-----.--....40---.-....---...50..-.......----60-.--.------...--.---...70....-....80.......-------.90----.......----------.100---......---.110...----....120...----....----------------130........140----.-.....-...150---........-----------.160.---------......170--.---......180...----..---..190.-...------...200.....-..210--........-.220--.--...-.-....230..-..-...240.....----..-250.......260.----------.....---.-----270...-....280.-.......290..---------....----..--------.300.--...------...----310.--------------..--....320.----....-----..330..-.-....340.......350..---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----------------------------------------------------------------------------MFR-------
P
R
L
L
L
T
S
L
A
I
A
L-------------GACSPQ
D
P
---
Q
A
--
V
T
S
A
A
L
A
Q
Q
-----
V
--
I
L
P
T
Y
S
---
R
-
W
V
E
A
---
D
Q
A
L
-
A
S
-
S
A
L
A
Y
CQ----
G
--
K
--
E
------
D
L
A
--
K
---
A
R
D
A
F
H
A
A
Q
-
K
A
W
A
ELQ
P
L
L
I
G
P-------LAE----G
N
R
A
W
Q
V
----------
Q
FWP---
D
K
K
D
L
V
---
G
R
Q
V
E
Q
L
----
L
KNNPQV
D
A
A
----
A
L
A
K
----------------
A
-
S
V
V
V
Q
G
L
S
A
Y
------
E
-
Y
I
L
FD-SKID-----LADAATKA-----------RY
C
P
L
---------
L
E
A
IG
T
H
Q
Q
--
Q
---
L
A
Q
D
I
L
A
R
WKND----G
G
---
M
L
T
Q
M
S
-KFP------NDRYA
D
A
H
E
A
I
-
A
E
L
----
L
R
V
Q
V
T
A
L
-
D
M
----
L
--
K
K
K
-L-GTPLGRQSK-GI-PQPY
Q
A
E
A
WRS----NA-S
L
A
S
L
D
ASL
S
G
A
Q
A
----------
L
W
EGI---D-----GKG
L
K
T
-LLPA
E
-
Q
K
-
D
LAGKI
D
A
--AY---------ADSH----
A
K
--------
L
A
A
L
E
--QK
P
------
L
S
E
----
L
L
AS--------------ED--G
R
N
Q
L
N
A
L
----
Y
D
S
L
-----
N
V
V
H
R
LH-E-
G
D
L
A
R
A
L
G
V
Q
LGFNANDGD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
73.92
15%
-70
- C6 -
3WSC
-
?
A:
[26-276]
-----------------------------------------------------------------------------------------------------------------------VAP
L
D
L
V
Q
P
I
S
D
Y
K
-
I
-----
Y
--
V
S
E
N
L
Q
---
T
-
L
V
R
D
---
T
R
E
F
-
T
N
-
A
V
K
A
-------------
G
------
D
V
A
--
K
---
A
K
K
L
F
A
S
T
R
-
M
S
Y
E
R
I
E
P
I
A
-
E
L
-------
F
S
------
D
L
D
A
S
I
----------
D
S
R
A
---
D
D
H
E
K
A
---
E
--------------------------------------------
K
-
D
P
A
F
F
G
F
H
R
I
------
E
-
Y
G
L
F
A
-
Q
N
S
A
---------------------------
K
G
---------
L
A
P
V
A
D
K
L
M
--
A
---
D
V
L
E
L
Q
K
R
I
R
G
L
---------
T
-----------------------
F
P
P
-
E
K
V
----
V
G
G
A
A
V
L
M
-
E
E
----
V
A
-
A
T
K
-
I
-
S
----------------
G
E
E
D
R
Y
S
----
H
T
-
D
L
W
D
F
Q
A
N
F
E
G
A
K
K
----------
I
V
D
L
-------------
F
R
P
-
L
V
V
K
D
-
N
R
-
A
F
A
D
K
V
D
A
--
N
F
---------
D
T
V
F
----
K
T
--------
L
A
K
Y
R
---
T
A
DGGFEL
Y
G
K
----
L
-
S
--------------------
E
R
D
R
K
V
L
----
A
G
R
V
-----
N
T
L
A
E
D
L
-
S
-
K
-
M
R
G
L
L
G
L
D
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
70.29
27%
15
- C6 -
3PF0
-
?
A:
[83-383]
-----------------------------------------------------------------------------------------------------------------------------------
V
A
N
D
-----
M
--
V
I
P
A
Y
A
---
D
-
A
A
K
Q
---
S
D
L
L
-
H
D
-
L
A
Q
K
H
C
Q
K
APV
S
--
G
--
D
------
E
L
Q
--
A
---
L
R
D
Q
W
L
V
L
A
-
Q
A
W
A
S
A
E
M
V
N
F
G
P
-------
A
T
A
----
S
M
S
N
L
Y
I
----------
N
Y
Y
P
---
D
E
R
G
L
V
---
H
G
G
V
A
D
L
----
I
T
A
N
P
A
L
T
A
E
----
Q
L
A
N
----------------
E
-
S
A
V
V
Q
G
I
P
G
L
------
E
-
E
A
L
Y
A
-
N
--
D
-----
S
L
D
A
G
Q
C
A
-----------
Y
V
M
S
A
---------
S
S
A
L
G
T
R
---------
L
K
D
I
E
K
N
W
Q
Q
N
----
A
I
---
K
L
L
A
I
------------
D
K
T
A
E
S
D
Q
G
L
-
N
Q
W
----
F
N
S
L
L
S
L
V
-
E
T
----
M
--
K
S
N
A
I
-
E
Q
P
L
G
L
S
G
K
-
A
K
-
G
H
L
P
A
A
T
A
G
Q
S
R
A
I
I
N
A
-
K
L
A
T
L
N
K
A
M
T
--
D
P
----------
V
L
T
A
I
---
L
-----
G
S
N
--------
N
-
E
N
-
T
V
A
D
T
L
S
T
--
A
L
---------
A
D
T
T
----
A
L
--------
L
A
-----
Q
M
P
--------
E
----
D
L
A
T
--------------
A
D
--
K
A
T
Q
-
Q
E
L
----
Y
D
H
L
-----
T
N
I
T
R
L
I
-
K
-
S
Q
L
I
P
T
L
G
I
R
V
G
F
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
68.73
24%
3
* C6 *
3PF0
-
?
A:
[78-383]
------------------------------------------------------------------------------------------------------------------------------
T
Y
L
T
H
V
A
N
D
-----
M
--
V
I
P
A
Y
A
---
D
-
A
A
K
Q
---
S
D
L
L
-
H
D
-
L
A
Q
K
H
C
Q
----
K
--
A
PV
S
G
D
----
E
L
Q
--
A
---
L
R
D
Q
W
L
V
L
A
-
Q
A
W
A
S
A
E
M
V
N
F
G
P
-------
A
T
A
----
S
M
S
N
L
Y
I
----------
N
Y
Y
P
---
D
E
R
G
L
V
---
H
G
G
V
A
D
L
----
I
T
A
N
P
A
L
T
A
E
----
Q
L
A
N
----------------
E
-
S
A
V
V
Q
G
I
P
G
L
------
E
-
E
A
L
Y
A
-
N
D
S
L
-----------
D
A
-----------
G
Q
C
A
Y
---------
V
M
S
A
S
S
A
L
G
--
T
---
R
L
K
D
I
E
K
N
W
Q
Q
N
---------
A
I
K
-
L
L
-
A
I
--------
D
K
T
A
E
S
D
Q
G
L
-
N
Q
W
----
F
N
S
L
L
S
L
V
-
E
T
----
M
K
-
S
N
A
-
I
-
E
Q
P
L
G
L
S
G
K
-----
A
K
G
H
L
P
A
A
T
A
----
G
Q
-
S
R
A
I
I
N
A
K
L
A
T
L
N
K
----------
A
M
T
D
P
-----------
V
L
T
A
-
I
L
G
S
N
-
N
E
N
T
V
A
D
T
L
S
T
--
A
L
---------
A
D
T
T
----
A
L
--------
L
A
Q
M
P
---
E
D
------
L
A
T
----
A
---------------------
D
K
A
T
Q
Q
E
L
----
Y
D
H
L
-----
T
N
I
T
R
L
I
-
K
-
S
Q
L
I
P
T
L
G
I
R
V
G
F
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
Fugue
66.34
15%
-40
- C6 -
3AT7
-
?
A:
[25-275]
-------------------------------------------------------------------------------------------------------------------
V
A
P
L
---
D
L
--
V
Q
P
I
S
D
Y
K
I
-----
Y
--
V
S
E
N
L
Q
---
T
-
L
V
R
D
---
T
R
E
F
-
T
N
-
A
V
K
A
-------------
G
------
D
V
A
--
K
---
A
K
K
L
F
A
S
T
R
-
M
S
Y
E
R
I
E
P
I
A
----------------------------------
E
L
F
S
---
D
L
D
A
S
I
---
D
S
R
A
D
D
H
----
E
K
A
E
K
D
P
A
-------------------------------
F
F
G
F
H
R
I
------
E
-
Y
G
L
F
A
-
Q
N
S
A
-------------------------------------------
K
G
L
A
--
P
---
V
A
D
K
L
M
A
D
V
L
E
L
----
Q
K
---
R
I
R
G
L
T
-
F
P
P
------
E
K
V
V
G
G
A
A
V
L
M
-
E
E
V
----
A
A
T
K
I
S
G
-----------------------------------
E
E
D
R
Y
S
----
H
T
-
D
L
W
D
F
Q
A
N
F
E
G
A
K
K
----------
I
V
D
L
-------------
F
R
P
-
L
V
V
K
D
-
N
R
-
A
F
A
D
K
V
D
A
--
N
F
---------
D
T
V
F
----
K
T
--------
L
A
K
Y
R
--
T
A
D
------
G
G
F
----
E
L
Y
G
--------------
K
L
--
S
E
R
D
R
K
V
L
----
A
G
R
V
-----
N
T
L
A
E
D
L
-
S
--
K
M
R
G
L
L
G
L
D
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
Fugue
62.29
18%
-37
- C2 -
4IUW
16
?
A:
[4-633]
LPRIQDD
L
Y
L
A
V
N
G
E
W
Q
A
K
TPIPPDKSVVS
A
D
S
N
L
T
D
D
I
R
Q
K
L
V
A
D
L
S
T
M
T
KTAKT
L
P
L
Q
Y
A
A
R
L
F
A
K
A
N
D
Q
T
R
R
Q
Q
L
G
-------
I
E
P
V
R
D
R
I
S
F
L
M
-------------
A
L
T
T
L
D
Q
F
---
R
S
--
A
M
P
K
L
V
A
D
Q
-----
Y
--
V
L
P
-
I
S
---
P
-
Y
V
D
A
---
D
M
H
D
-
A
E
-
H
N
I
L
N
L
G
----
G
--
P
--
D
T
ILPD
A
A
M
Y
--
N
---
Q
E
D
A
E
N
A
A
D
L
A
A
W
S
Q
M
A
A
A
M
L
A
A
-------
V
------
G
F
S
Q
T
D
Q
----------
T
A
Y
V
---
E
A
A
K
R
F
---
D
R
R
L
A
D
Y
----
V
P
A
N
V
D
L
A
V
D
----
S
T
Y
-----------------------------------------
D
-
N
P
L
S
-----
W
Q
A
F
E
D
A
A
-----------
G
Y
L
G
I
---------
P
Q
A
F
A
T
Y
M
P
--
Q
---
T
P
A
K
V
N
A
V
V
P
A
Y
----
L
P
---
H
L
S
K
L
L
-
T
P
D
------
N
Y
S
E
W
H
A
W
M
V
I
-
N
E
L
----
L
T
C
A
-
T
Y
L
-
S
D
----
D
--
L
R
Q
-
L
-
A
G
Q
Y
D
R
F
L
A
-
G
Q
-
P
E
---
A
S
S
W
T
K
----
H
A
F
G
I
A
N
E
Y
F
D
D
V
I
G
Q
Y
----------
Y
G
Q
T
Y
---
F
-----
G
A
D
A
K
A
-
D
V
T
A
M
-
V
K
-
Q
I
L
A
Q
Y
R
V
--
Q
L
---------
E
N
N
T
WLS-
P
A
--------
T
K
Q
K
A
--
M
R
K
------
L
A
T
----
M
Q
V
K
--------------
M
G
--
Y
P
A
R
L
F
S
L
----
Y
D
H
L
-----
S
V
D
V
----
D
-
D
D
L
L
T
A
I
---
L
K
L
S
A
Q
T
Q
A
F
W
F
K
Q
L
GQTVDRNQWNMPGHLV
N
A
S
Y
D
PLKN
D
I
T
F
P
AGILQPPYYSLKWT
R
A
E
N
L
G
G
T
G
A
T
I
G
H
E
I
S
H
S
F
D
N
N
G
A
L
Y
DEYGNLHNWWT
P
A
D
K
Q
A
F
D
Q
L
V
K
A
M
A
A
Q
F
DGRDYEG
V
K
V
N
GTLT
V
S
E
N
M
A
D
N
A
G
M
D
V
A
L
A
L
L
GDQPD
V
K
D
L
Q
A
F
F
I
T
Y
A
R
S
W
A
T
K
M
R
P
E
R
A
K
T
V
L
R
QDVHAP
A
T
L
R
V
N
V
P
V
Q
N
F
P
A
W
Y
Q
A
F
NVQPQDGMYRQPQK
R
L
T
I
WHQ
35
Fugue
57.17
20%
-41
* C5 *
4QT9
2
?
A:
[19-432]
--------------------------------------------------------------------LS
D
D
A
L
M
D
T
V
Q
-------
R
R
T
F
L
Y
F
W
E
G
A
E
PNSGLAPERYHVD
G
V
Y
P
Q
N
D
A
---
N
V
--
V
T
S
G
G
S
G
F
G
-----
I
M
A
I
L
A
G
I
D
---
R
G
Y
V
T
R
---
E
E
G
L
-
A
R
M
E
R
I
V
-------------
S
------
F
L
E
--
K
---
A
-
D
R
F
H
G
A
Y
-
P
H
W
W
Y
G
D
T
G
K
V
K
P
-------
F
G
Q
KDNG
G
D
L
V
E
T
A
F
L
M
Q
G
L
L
A
V
H
Q
Y
Y
A
NGN
D
K
E
K
A
I
---
A
Q
R
I
D
R
L
----
W
R
E
---
V
D
W
D
----
W
Y
R
K
GGQNVLYWHWSPTYGW
E
M
D
F
P
I
H
G
Y
N
E
C
M
-----
I
M
Y
I
L
A
A
A
S
P
T
H
-----
G
V
P
A
A
V
Y
H
-----------
D
G
W
A
Q
---------
N
G
A
I
V
S
P
H
K
--
V
---
E
G
I
E
L
H
L
R
Y
Q
G
T
----
E
A
GP
L
F
W
A
Q
Y
S
-
F
L
G
LDPVGL
K
D
E
Y
C
P
S
Y
F
H
E
M
R
N
L
----
T
L
V
N
R
A
Y
C
-
I
R
----
N
--
P
K
H
-
Y
--
K
G
F
G
P
D
C
W
-
G
L
-
T
A
S
Y
S
V
D
G
Y
A
A
----
H
S
-
P
N
E
Q
D
D
K
G
V
I
S
P
T
A
----------
A
L
S
S
I
VYT
P
-----
E
Y
S
L
Q
V
M
R
H
L
Y
N
M
G
D
-
K
V
F
G
P
F
G
F
YD
A
F
---------
S
E
T
D
NWYP
Q
R
--------
Y
L
A
I
D
--
Q
G
P
------
I
A
V
M
---
I
E
N
Y
--------------
R
T
--
G
---------------------
L
L
W
K
L
F
M
S
-
H
P
D
V
Q
A
G
L
T
K
L
G
F
N
T
N
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
55.22
26%
-53
- C6 -
3N8U
3
?
A:
[237-352]
--------------------------------------------------------------------------------------------------------------------------------------------
V
--
V
V
P
T
Y
K
---
S
-
L
K
E
K
---
N
D
A
L
-
Y
N
-
A
V
I
V
L
A
D
----
N
--
P
--
S
------
N
S
A
F
E
T
---
A
C
D
A
W
I
T
A
R
-
E
P
W
E
K
S
E
A
F
L
F
G
P
-------
V
D
E
----
M
G
L
D
P
N
M
----------
D
S
W
P
L--
D
Q
N
A
I
V
Q
I
L
N
S
Q
S
W
S
D
----
L
E
W
S
E
G
D
D
E
A
----
A
V
E
S
----------------
A
-
Q
-
N
V
R
G
F
H
T
L
------
E
-
F
L
L
Y
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
HHSearch
53.14
14%
-56
- C6 -
3OYV
3
?
A:
[20-218]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
A
S
-----------
S
W
H
N
Y
---------
M
R
N
V
A
A
L
L
K
--
T
---
D
A
T
N
L
Y
N
A
W
N
S
S
YKGG
E
S
---
Y
A
S
L
F
K
-
A
H
S
------
G
S
P
Y
A
S
A
L
S
C
V
-
E
E
I
----
V
D
K
C
A
E
I
A
-
N
E
----
V
G
-
T
A
K
-
I
-
G
D
P
Y
N
L
Y
K
A
G
N
T
E
E
A
L
Y
A
V
E
S
W
Y
S
----
W
H
-
S
R
D
D
Y
T
N
N
I
Y
S
I
R
N
----------
A
Y
Y
G
S
---
L
DGNIN
A
N
S
L
S
T
-
V
I
A
G
A
-
N
S
-
S
L
D
T
K
I
K
N
--
A
I
---------
Q
K
A
A
----
K
A
--------
I
Q
D
I
P
---
Q
P
------
F
R
N
----
H
I
P
S
--------------
N
------
E
T
V
A
A
----
M
D
A
C
-----
A
E
L
E
S
I
L
-
K
-
N
D
L
K
S
Y
I
A
N
N
S
N
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
51.46
26%
-35
- C6 -
3OYV
2
?
A:
[237-352]
--------------------------------------------------------------------------------------------------------------------------------------------
V
--
V
V
P
T
Y
K
---
S
-
L
K
E
K
---
N
D
A
L
-
Y
N
-
A
V
I
V
L
A
D
----
N
--
P
--
S
------
N
S
A
F
E
T
---
A
C
D
A
W
I
T
A
R
-
E
P
W
E
K
S
E
A
F
L
F
G
P
-------
V
D
E
----
M
G
L
D
P
N
M
----------
D
S
W
P
L--
D
Q
N
A
I
V
Q
I
L
N
S
Q
S
W
S
D
----
L
E
W
S
E
G
D
D
E
A
----
A
V
E
S
----------------
A
-
Q
-
N
V
R
G
F
H
T
L
------
E
-
F
L
L
Y
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
48.76
20%
-43
- C6 -
3OYV
2
?
A:
[228-358]
------------------------------------------------------------------------------------------------------------------------------
P
V
V
T
Q
Y
V
D
A
-----
V
--
V
V
P
T
Y
K
---
S
-
L
K
E
K
---
N
D
A
L
-
Y
N
-
A
V
I
V
L
A
D
----
N
--
P
--
S
N
S
----
A
F
E
--
T
---
A
C
D
A
W
I
T
A
R
-
E
P
W
E
K
S
E
A
F
L
F
G
P
-------
V
D
E
----
M
G
L
D
P
N
M
----------
D
S
W
P
---
L
D
Q
N
A
I
---
V
Q
I
L
N
S
Q
S
W
S
D
L
E
-
W
S
E
G
D
D
E
----
A
A
V
E
----------------
S
-
A
Q
N
V
R
G
F
H
T
L
------
E
-
F
L
L
Y
K
-
N
G
E
P
-----
R
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
39
Fugue
45.45
21%
-34
- C4 -
4Q6O
8
?
A:
[21-437]
----------------------------------------------------------------------------
M
I
E
KAPTNVE
D
R
D
K
A
P
H
L
L
L
L
A
-------------
G
I
Q
G
D
E
----------
P
G
G
F
N
A
T
N
-----
L
--
F
L
M
H
Y
S
VL
K
G
-
L
V
E
V
---
V
P
V
L
N
K
P
-
S
M
L
R
N
H
R
----
G
--
L
Y-
G
------
D
M
N
--
R
KFA
A
L
D
K
N
D
P
E
Y
-
P
T
I
Q
E
I
K
S
L
I
A
K
P
SID
A
V
L
H
L
H
D
----
G
G
G
Y
Y
R
-----------
P
V
Y
V
---
D
A
M
L
N
P
---
K
R
W
G
N
C
F
----
I
I
D
Q
D
E
V
K
G
A
KFPN
L
L
A
F
----------------
A
-
N
N
T
I
E
S
I
N
A
H
LLHPIE
E
-
Y
H
L
K
N
-
T
R
T
A
QGD
T
E
M
Q
K
A
L
T
F
Y
-----------
A
I
N
Q
K
---------
K
S
A
F
A
N
E
A
S
--
K
ELP
L
A
S
R
V
F
Y
H
L
Q
A
I
----
E
G
---
L
L
N
Q
L
N
I
P
F
K
------
R
D
F
D
L
N
P
N
S
V
H
-
A
L
I
N
DKN
L
W
A
K
I
S
S
L
P
K
M
PLFN
L
--
R
P
K
-
L
N
H
F
P
L
P
H
N
T
K
--
I
-
P
Q
I
----
P
I
E
S
----
N
A
-
Y
I
V
G
L
V
K
N
K
Q
E
V
F
L
----------
K
Y
------------
G
N
K
L
M
T
-
R
L
S
P
F
-
Y
I
-
E
F
D
P
S
L
E
E
--
V
K
---------
M
Q
I
D
----
N
K
--------
D
Q
M
V
K
--
I
G
S
------
V
V
E
V
K
E
S
F
Y
I
H
--------------
A
M
--
D
N
I
R
A
N
V
I
----
G
F
S
V
-----
S
N
E
N
K
P
N
-
E
A
G
Y
T
I
K
F
K
D
F
Q
K
R
F
S
L
D
K
Q
E
R
I
Y
R
I
E
F
Y
KNNAFS
G
M
I
L
V
K
F
V-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
Fugue
44.50
14%
-10
* C4 *
2YHG
12
?
A:
[27-437]
-----------------------------------------------------------------------------
G
R
-------
Y
R
V
I
H
T
T
D
M
G
A
-----------------
D
P
D
D
E
---
Q
S
--
L
V
R
Q
L
V
M
A
N
EYDLE
G
--
I
I
T
T
T
G
---
C
-
W
K
K
S
TSN
T
A
Y
V
-
D
R
-
I
L
N
A
Y
S
Q
----
A
--
Y
--
P
------
N
L
S
--
K
---
H
A
E
G
F
P
T
P
A
-
Y
L
D
S
I
N
V
M
---
G
Q
-------
R
G
Y
----
G
M
G
D
V
G
S
----------
G
K
D
S
---
A
G
S
N
L
I
---
I
A
A
V
D
K
------
D
D
P
R
P
V
W
A
T
----
C
W
G
G
----------------
C
-
N
T
I
A
Q
A
V
W
K
V
------
Q
-
N
T
--
R
-
S
Q
A
Q
-----
L
D
A
F
I
S
K
L
-----------
R
V
Y
D
I
LGQDN
A
G
T
W
L
A
K
N
F
P
N
L
I
--
Y
---
I
R
A
R
S
V
Y
S
W
Q
P
S
----
D
S
---
Y
L
D
N
H
I
-
Q
S
H
------
G
A
L
G
A
V
Y
P
N
R
R
-
Y
A
T
----
E
G
D
T
P
A
F
L
-
H
M
----
A
--
N
P
G
-
L
-
N
D
P
S
V
V
S
M
G
-
G
W
-
G
G
R
F
P
S
K
Q
A
G
V
----
R
G
-
M
S
C
M
S
G
E
D
A
V
Y
D
T
Y
----------
Y
M
Y
T
E
---
N
-----
G
E
S
I
K
R
-
W
S
T
A
I
-
H
N
-
D
F
Q
A
R
M
D
W
--
A
I
---------
E
S
N
Y
----
S
A
A
N
H
H
P
V
P
V
V
N
N
D
A
--
N
E
A
------
V
M
Y
----
L
N
A
S
--------------
A
G
--
S
T
V
S
L
D
A
S
GSSD
P
D
G
D
-----
S
L
N
Y
S
W
S
-
H
-
Y
G
E
A
D
S
Y
S
G
S
V
S
I
S
N
S
S
S
A
S
A
N
V
Q
I
P
SNAGG
K
D
I
H
I
L
L
T
L
R
D
NGSP
N
L
Y
A
Y
R
R
V
V
I
N
V
Q-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
42.11
28%
2
- C3 -
4ECG
2
?
A:
[24-97]
---------------------------------------------------------------------------------------------------------------
G
A
K
P
T
E
D
Q
---
M
S
--
A
V
V
A
T
F
V
D
E
-----
V
--
A
L
P
T
Y
K
---
D
-
M
L
T
K
---
M
T
A
Y
-
K
N
-
A
V
D
K
F
I
A
----
S
GS
K
--
N
------
D
L
A
--
D
---
A
C
D
A
W
R
A
V
R
-
V
P
W
E
Q
S
E
A
F
L
F
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
Fugue
39.91
11%
-34
- C1 -
4XRP
4
?
C:
[1-435]
--------------------------------M
I
L
Q
I
H
S
QNPH
L
L
D
L
L
NKNPHTDLG
I
Y
A
K
S
L
RN
G
Q
L
I
G
N
AVSAY
Q
Y
D
-------
V
V
F
Q
D
T
R
Y
S
Y
L
P
-------------
E
E
S
N
Q
I
D
F
---
Q
S
--
Y
C
S
P
L
V
I
L
H
-----
I
--
C
N
E
F
F
K
---
E
-
L
L
Q
E
---
K
Q
T
Y
-
W
S
-
Q
Q
I
K
W
L
E
----
R
--
T
--
R
------
A
E
V
--
D
---
T
Y
P
C
T
I
E
V
K
-
N
L
Y
A
N
S
T
W
Y
S
K
G
H
-------
F
M
M
----
E
R
Y
F
K
N
I
----------
H
I
-------
T
P
I
V
---
G
N
N
L
S
L
R
----
V
E
G
K
S
V
F
E
A
M
----
N
L
L
S
----------------
F
-
I
A
V
T
T
H
I
T
N
T
------
Y
-
G
E
Y
T
Y
-
I
D
D
H
-----
F
A
Q
K
Y
A
R
I
LTNIPQVP
Y
F
V
F
Y
L
F
I
---------
K
R
A
I
K
S
E
R
Q
F
A
E
---
I
K
P
M
F
E
A
Y
F
K
E
E
----
G
L
---
D
I
D
F
Q
F
----------
T
D
T
H
G
S
R
M
D
F
I
-
V
K
E
----
L
G
M
E
Y
P
I
L
-
D
I
----
G
CG
E
L
K
-
Y
-
Y
R
R
F
M
R
R
N
Y
-
N
Y
-
S
H
P
Y
F
A
T
D
T
D
K
----
S
---------
V
G
D
Y
A
A
L
----------
L
K
E
R
M
---
E
-----
A
D
N
L
Y
F
-
F
S
D
W
T
-
D
Y
-
E
Y
K
N
P
V
N
I
--
I
L
TEVIEHNT
P
E
A
A
E
----
A
L
--------
V
K
H
C
L
--
S
L
N
------
F
H
K
----
M
I
I
T
T
P
N
SLFNKYYFHH
F
E
W
--
T
P
Q
E
F
Q
D
F
----
I
R
H
C
V
GDTS
L
E
V
T
Y
C
G
-
I
-
G
D
R
I
N
G
E
T
P
T
Q
A
V
V
I
T
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
37.29
32%
44
- C3 -
4PMY
3
?
A:
[42-136]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
A
V
R
D
----
Q
M
-
D
W
S
T
L
D
A
A
Y
R
F
A
Q
A
N
Q
M
P
F
Q
M
HVM
V
W
G
N
Q
---
Q
-----
P
E
W
I
K
T
-
L
R
P
A
E
-
Q
R
-
R
E
I
E
Q
W
F
A
--
A
V
---------
A
Q
R
Y
----
P
D
--------
I
A
L
L
E
VV
N
E
P
------
L
N
D
----
P
P
S
K
--------------
A
D
TG
G
G
N
Y
L
Q
A
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
36.58
32%
44
- C3 -
4PMZ
2
?
A:
[42-136]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
A
V
R
D
----
Q
M
-
D
W
S
T
L
D
A
A
Y
R
F
A
Q
A
N
Q
M
P
F
Q
M
HVM
V
W
G
N
Q
---
Q
-----
P
E
W
I
K
T
-
L
R
P
A
E
-
Q
R
-
R
E
I
E
Q
W
F
A
--
A
V
---------
A
Q
R
Y
----
P
D
--------
I
A
L
L
E
VV
N
E
P
------
L
N
D
----
P
P
S
K
--------------
A
D
TG
G
G
N
Y
L
Q
A
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
36.38
32%
49
- C3 -
4PN2
4
?
A:
[43-137]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
A
V
R
D
----
Q
M
-
D
W
S
T
L
D
A
A
Y
R
F
A
Q
A
N
Q
M
P
F
Q
M
HVM
V
W
G
N
Q
---
Q
-----
P
E
W
I
K
T
-
L
R
P
A
E
-
Q
R
-
R
E
I
E
Q
W
F
A
--
A
V
---------
A
Q
R
Y
----
P
D
--------
I
A
L
L
E
VV
N
E
P
------
L
N
D
----
P
P
S
K
--------------
A
D
TG
G
G
N
Y
L
Q
A
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_CBE
36.37
32%
46
- C3 -
4PN2
4
?
B:
[43-137]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
A
V
R
D
----
Q
M
-
D
W
S
T
L
D
A
A
Y
R
F
A
Q
A
NQMPFQMHVM
V
W
G
N
Q
---
Q
-----
P
E
W
I
K
T
-
L
R
P
A
E
-
Q
R
-
R
E
I
E
Q
W
F
A
--
A
V
---------
A
Q
R
Y
----
P
D
--------
I
A
L
L
E
VV
N
E
P
------
L
N
D
----
P
P
S
K
--------------
A
D
TG
G
G
N
Y
L
Q
A
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_CBE
35.48
32%
44
* C3 *
4PMY
3
?
B:
[42-136]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
A
V
R
D
----
Q
M
-
D
W
S
T
L
D
A
A
Y
R
F
A
Q
A
NQMPFQMHVM
V
W
G
N
Q
---
Q
-----
P
E
W
I
K
T
-
L
R
P
A
E
-
Q
R
-
R
E
I
E
Q
W
F
A
--
A
V
---------
A
Q
R
Y
----
P
D
--------
I
A
L
L
E
VV
N
E
P
------
L
N
D
----
P
P
S
K
--------------
A
D
TG
G
G
N
Y
L
Q
A
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
35.48
32%
46
- C3 -
4PMX
1
?
A:
[43-137]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
A
V
R
D
----
Q
M
-
D
W
S
T
L
D
A
A
Y
R
F
A
Q
A
N
Q
M
P
F
Q
M
HVM
V
W
G
N
Q
---
Q
-----
P
E
W
I
K
T
-
L
R
P
A
E
-
Q
R
-
R
E
I
E
Q
W
F
A
--
A
V
---------
A
Q
R
Y
----
P
D
--------
I
A
L
L
E
VV
N
E
P
------
L
N
D
----
P
P
S
K
--------------
A
D
TG
G
G
N
Y
L
Q
A
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------