@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : spr1234: (2018-01-07 )
MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEIEASDLVETVANIRRYQMFGINLSMPYKEQVIPYLDKLSDEARLIGAVNTVVNENGNLIGYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEKTRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVLPETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIWQSLTEKYQ
Atome Classification :
(47 SA)
.........10........20........30.....----...40........50........60........70........80........90.....-...100.......110...--.--..--.--120.......130.......140.......150...----..---..-160.......170.....-..180.......190.......200...---.--...-210.-.-...---..220.......230.......240....-.-..250.......260.......270.......280..
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MKLD
G
Y
T
R
L
A
A
V
V
A
N
P
I
K
H
S
I
S
P
F
I
HNRAFEATATN----
G
A
Y
V
A
W
E
I
E
A
S
D
L
V
E
T
V
A
N
I
R
R
Y
Q
M
F
G
I
NLSMP
Y
K
E
Q
V
I
P
Y
L
D
KLSD
E
A
R
L
I
G
A
V
N
T
V
VN-ENG
N
L
I
G
YNTDG
K
G
F
F
K
CL--P--SF--T--ISG
K
K
M
T
L
L
GAG
G
A
A
K
S
I
L
A
Q
A
I
L
D
G
V
S
Q
I
S
V
F
V
R
S
----VS---ME-KT
R
P
Y
L
D
K
L
Q
E
QTG
F
K
V
D
-
L
C
A
L
E
Y
V
S
E
L
Q
A
R
IAES
D
L
L
V
N
A
T
SVGM---D--GQS-SPVP-E-NIV---L
P
E
T
L
L
V
A
D
I
I
YQPFE
T
P
F
L
K
W
A
RSQGNP-
A
-
V
N
G
L
G
M
L
L
Y
Q
A
A
E
A
F
Q
LWTGKEM
P
T
E
E
I
W
Q
S
L
T
E
KYQ
26
PsiBlast_CBE
86.60
42%
-32
- C5 -
-
3TOZ
1
AROE_LISMO
C:
[32-314]
-
R
I
T
G
H
T
E
L
I
G
L
I
A
T
P
I
R
H
S
L
S
P
T
M
H
N
E
A
F
A
K
L
G
L
D
----
Y
V
Y
L
A
F
E
V
G
D
K
E
L
K
D
V
V
Q
G
F
R
A
M
N
L
R
G
W
N
V
S
M
P
N
K
T
N
I
H
K
Y
L
D
K
L
S
P
A
A
E
L
V
G
A
V
N
T
V
V
N
-
D
D
G
V
L
T
G
H
I
T
D
G
T
G
Y
M
R
A
L
--
K
E
A
G
H
--
D
--
I
I
G
K
K
M
T
I
C
G
A
G
G
A
A
T
A
I
C
I
Q
A
A
L
D
G
V
K
E
I
S
I
F
N
R
K
DDF
Y
A
N
---
A
E
-
K
T
---
V
E
K
I
N
S
K
T
D
C
K
A
Q
-
L
F
D
I
E
D
H
E
Q
L
R
K
E
I
A
E
S
V
I
F
T
N
A
T
G
V
G
M
KPF
E
--
G
E
T
-
L
L
P
S
-
A
-
D
M
L
---
R
P
E
-
L
I
V
S
D
V
V
Y
K
P
T
K
T
R
L
L
E
I
A
E
E
Q
G
C
Q
-
T
-
L
N
G
L
G
M
M
L
W
Q
G
A
K
A
F
E
I
W
T
H
K
E
M
P
V
D
Y
I
K
E
I
L
-----
25
PsiBlast_CBE
86.19
42%
-32
- C5 -
-
3TOZ
1
AROE_LISMO
D:
[32-314]
-
R
I
T
G
H
T
E
L
I
G
L
I
A
T
P
I
R
H
S
L
S
P
T
M
H
N
E
A
F
A
K
L
G
L
D
----
Y
V
Y
L
A
F
E
V
G
D
K
E
L
K
D
V
V
Q
G
F
R
A
M
N
L
R
G
W
N
V
S
M
P
N
K
T
N
I
H
K
Y
L
D
K
L
S
P
A
A
E
L
V
G
A
V
N
T
V
V
N
-
D
D
G
V
L
T
G
H
I
T
D
G
T
G
Y
M
R
A
L
--
K
EA
G
H
--
D
--
I
I
G
K
K
M
T
I
C
G
A
G
G
A
A
T
A
I
C
I
Q
A
A
L
D
G
V
K
E
I
S
I
F
N
R
K
DDFY
A
N
---
A
E
-
K
T
---
V
E
K
I
N
S
K
T
D
C
K
A
Q
-
L
F
D
I
E
D
H
E
Q
L
R
K
E
I
A
E
S
V
I
F
T
N
A
T
G
V
G
M
KPF
E
--
G
E
T
-
L
L
P
S
-
A
-
D
M
L
---
R
P
E
-
L
I
V
S
D
V
V
Y
K
P
T
K
T
R
L
L
E
I
A
E
E
Q
G
C
Q
-
T
-
L
N
G
L
G
M
M
L
W
Q
G
A
K
A
F
E
I
W
T
H
K
E
M
P
V
D
Y
I
K
E
I
L
-----
1
PsiBlast_PDB
86.16
42%
-32
- C5 -
-
3TOZ
2
AROE_LISMO
A:
[32-314]
-
R
I
T
G
H
T
E
L
I
G
L
I
A
T
P
I
R
H
S
L
S
P
T
M
H
N
E
A
F
A
K
L
G
L
D
----
Y
V
Y
L
A
F
E
V
G
D
K
E
L
K
D
V
V
Q
G
F
R
A
M
N
L
R
G
W
N
V
S
M
P
N
K
T
N
I
H
K
Y
L
D
K
L
S
P
A
A
E
L
V
G
A
V
N
T
V
V
N
-
D
D
G
V
L
T
G
H
I
T
D
G
T
G
Y
M
R
A
L
--
K
E
A
G
H
--
D
--
I
I
G
K
K
M
T
I
C
G
A
G
G
A
A
T
A
I
C
I
Q
A
A
L
D
G
V
K
E
I
S
I
F
N
R
K
DDF
Y
A
N
---
A
E
-
K
T
---
V
E
K
I
N
S
K
T
D
C
K
A
Q
-
L
F
D
I
E
D
H
E
Q
L
R
K
E
I
A
E
S
V
I
F
T
N
A
T
G
V
G
M
KPF
E
--
G
E
T
-
L
L
P
S
-
A
-
D
M
L
---
R
P
E
-
L
I
V
S
D
V
V
Y
K
P
T
K
T
R
L
L
E
I
A
E
E
Q
G
C
Q
-
T
-
L
N
G
L
G
M
M
L
W
Q
G
A
K
A
F
E
I
W
T
H
K
E
M
P
V
D
Y
I
K
E
I
L
-----
2
PsiBlast_PDB
86.14
42%
-32
- C5 -
-
3TNL
2
AROE_LISMO
A:
[32-314]
-
R
I
T
G
H
T
E
L
I
G
L
I
A
T
P
I
R
H
S
L
S
P
T
M
H
N
E
A
F
A
K
L
G
L
D
----
Y
V
Y
L
A
F
E
V
G
D
K
E
L
K
D
V
V
Q
G
F
R
A
M
N
L
R
G
W
N
V
S
M
P
N
K
T
N
I
H
K
Y
L
D
K
L
S
P
A
A
E
L
V
G
A
V
N
T
V
V
N
-
D
D
G
V
L
T
G
H
I
T
D
G
T
G
Y
M
R
A
L
--
K
E
A
G
H
--
D
--
I
I
G
K
K
M
T
I
C
G
A
G
G
A
A
T
A
I
C
I
Q
A
A
L
D
G
V
K
E
I
S
I
F
N
R
K
DDF
Y
A
N
---
A
E
-
K
T
---
V
E
K
I
N
S
K
T
D
C
K
A
Q
-
L
F
D
I
E
D
H
E
Q
L
R
K
E
I
A
E
S
V
I
F
T
N
A
T
G
V
G
M
KPF
E
--
G
E
T
-
L
L
P
S
-
A
-
D
M
L
---
R
P
E
-
L
I
V
S
D
V
V
Y
K
P
T
K
T
R
L
L
E
I
A
E
E
Q
G
C
Q
-
T
-
L
N
G
L
G
M
M
L
W
Q
G
A
K
A
F
E
I
W
T
H
K
E
M
P
V
D
Y
I
K
E
I
L
-----
29
PsiBlast_CBE
86.09
42%
-33
- C5 -
-
3TNL
2
AROE_LISMO
C:
[32-314]
-
R
I
T
G
H
T
E
L
I
G
L
I
A
T
P
I
R
H
S
L
S
P
T
M
H
N
E
A
F
A
K
L
G
L
D
----
Y
V
Y
L
A
F
E
V
G
D
K
E
L
K
D
V
V
Q
G
F
R
A
M
N
L
R
G
W
N
V
S
M
P
N
K
T
N
I
H
K
Y
L
D
K
L
S
P
A
A
E
L
V
G
A
V
N
T
V
V
N
-
D
D
G
V
L
T
G
H
I
T
D
G
T
G
Y
M
R
A
L
--
K
EA
G
H
--
D
--
I
I
G
K
K
M
T
I
C
G
A
G
G
A
A
T
A
I
C
I
Q
A
A
L
D
G
V
K
E
I
S
I
F
N
R
K
DDFY
A
N
---
A
E
-
K
T
---
V
E
K
I
N
S
K
T
D
C
K
A
Q
-
L
F
D
I
E
D
H
E
Q
L
R
K
E
I
A
E
S
V
I
F
T
N
A
T
G
V
G
M
KPF
E
--
G
E
T
-
L
L
P
S
-
A
-
D
M
L
---
R
P
E
-
L
I
V
S
D
V
V
Y
K
P
T
K
T
R
L
L
E
I
A
E
E
Q
G
C
Q
-
T
-
L
N
G
L
G
M
M
L
W
Q
G
A
K
A
F
E
I
W
T
H
K
E
M
P
V
D
Y
I
K
E
I
L
-----
24
PsiBlast_CBE
85.76
42%
-32
- C5 -
-
3TOZ
1
AROE_LISMO
E:
[32-314]
-
R
I
T
G
H
T
E
L
I
G
L
I
A
T
P
I
R
H
S
L
S
P
T
M
H
N
E
A
F
A
K
L
G
L
D
----
Y
V
Y
L
A
F
E
V
G
D
K
E
L
K
D
V
V
Q
G
F
R
A
M
N
L
R
G
W
N
V
S
M
P
N
K
T
N
I
H
K
Y
L
D
K
L
S
P
A
A
E
L
V
G
A
V
N
T
V
V
N
-
D
D
G
V
L
T
G
H
I
T
D
G
T
G
Y
M
R
A
L
--
K
EA
G
H
--
D
--
I
I
G
K
K
M
T
I
C
G
A
G
G
A
A
T
A
I
C
I
Q
A
A
L
D
G
V
K
E
I
S
I
F
N
R
K
DDFY
A
N
---
A
E
-
K
T
---
V
E
K
I
N
S
K
T
D
C
K
A
Q
-
L
F
D
I
E
D
H
E
Q
L
R
K
E
I
A
E
S
V
I
F
T
N
A
T
G
V
G
M
KPF
E
--
G
E
T
-
L
L
P
S
-
A
-
D
M
L
---
R
P
E
-
L
I
V
S
D
V
V
Y
K
P
T
K
T
R
L
L
E
I
A
E
E
Q
G
C
Q
-
T
-
L
N
G
L
G
M
M
L
W
Q
G
A
K
A
F
E
I
W
T
H
K
E
M
P
V
D
Y
I
K
E
I
L
-----
23
PsiBlast_CBE
85.09
42%
-32
- C5 -
-
3TOZ
1
AROE_LISMO
F:
[32-314]
-
R
I
T
G
H
T
E
L
I
G
L
I
A
T
P
I
R
H
S
L
S
P
T
M
H
N
E
A
F
A
K
L
G
L
D
----
Y
V
Y
L
A
F
E
V
G
D
K
E
L
K
D
V
V
Q
G
F
R
A
M
N
L
R
G
W
N
V
S
M
P
N
K
T
N
I
H
K
Y
L
D
K
L
S
P
A
A
E
L
V
G
A
V
N
T
V
V
N
-
D
D
G
V
L
T
G
H
I
T
D
G
T
G
Y
M
R
A
L
--
K
EA
G
H
--
D
--
I
I
G
K
K
M
T
I
C
G
A
G
G
A
A
T
A
I
C
I
Q
A
A
L
D
G
V
K
E
I
S
I
F
N
R
K
DDFY
A
N
---
A
E
-
K
T
---
V
E
K
I
N
S
K
T
D
C
K
A
Q
-
L
F
D
I
E
D
H
E
Q
L
R
K
E
I
A
E
S
V
I
F
T
N
A
T
G
V
G
M
KPF
E
--
G
E
T
-
L
L
P
S
-
A
-
D
M
L
---
R
P
E
-
L
I
V
S
D
V
V
Y
K
P
T
K
T
R
L
L
E
I
A
E
E
Q
G
C
Q
-
T
-
L
N
G
L
G
M
M
L
W
Q
G
A
K
A
F
E
I
W
T
H
K
E
M
P
V
D
Y
I
K
E
I
L
-----
30
PsiBlast_CBE
84.82
42%
-30
- C5 -
-
3TNL
1
AROE_LISMO
B:
[32-314]
-
R
I
T
G
H
T
E
L
I
G
L
I
A
T
P
I
R
H
S
L
S
P
T
M
H
N
E
A
F
A
K
L
G
L
D
----
Y
V
Y
L
A
F
E
V
G
D
K
E
L
K
D
V
V
Q
G
F
R
A
M
N
L
R
G
W
N
V
S
M
P
N
K
T
N
I
H
K
Y
L
D
K
L
S
P
A
A
E
L
V
G
A
V
N
T
V
V
N
-
D
D
G
V
L
T
G
H
I
T
D
G
T
G
Y
M
R
A
L
--
K
E
A
G
H
--
D
--
I
I
G
K
K
M
T
I
C
G
A
G
G
A
A
T
A
I
C
I
Q
A
A
L
D
G
V
K
E
I
S
I
F
N
R
K
DDF
Y
A
N
---
A
E
-
K
T
---
V
E
K
I
N
S
K
T
D
C
K
A
Q
-
L
F
D
I
E
D
H
E
Q
L
R
K
E
I
A
E
S
V
I
F
T
N
A
T
G
V
G
M
KPF
E
--
G
E
T
-
L
L
P
S
-
A
-
D
M
L
---
R
P
E
-
L
I
V
S
D
V
V
Y
K
P
T
K
T
R
L
L
E
I
A
E
E
Q
G
C
Q
-
T
-
L
N
G
L
G
M
M
L
W
Q
G
A
K
A
F
E
I
W
T
H
K
E
M
P
V
D
Y
I
K
E
I
L
-----
21
PsiBlast_CBE
84.80
42%
-32
- C5 -
-
3TOZ
1
AROE_LISMO
H:
[32-314]
-
R
I
T
G
H
T
E
L
I
G
L
I
A
T
P
I
R
H
S
L
S
P
T
M
H
N
E
A
F
A
K
L
G
L
D
----
Y
V
Y
L
A
F
E
V
G
D
K
E
L
K
D
V
V
Q
G
F
R
A
M
N
L
R
G
W
N
V
S
M
P
N
K
T
N
I
H
K
Y
L
D
K
L
S
P
A
A
E
L
V
G
A
V
N
T
V
V
N
-
D
D
G
V
L
T
G
H
I
T
D
G
T
G
Y
M
R
A
L
--
K
EA
G
H
--
D
--
I
I
G
K
K
M
T
I
C
G
A
G
G
A
A
T
A
I
C
I
Q
A
A
L
D
G
V
K
E
I
S
I
F
N
R
K
DDFY
A
N
---
A
E
-
K
T
---
V
E
K
I
N
S
K
T
D
C
K
A
Q
-
L
F
D
I
E
D
H
E
Q
L
R
K
E
I
A
E
S
V
I
F
T
N
A
T
G
V
G
M
KPF
E
--
G
E
T
-
L
L
P
S
-
A
-
D
M
L
---
R
P
E
-
L
I
V
S
D
V
V
Y
K
P
T
K
T
R
L
L
E
I
A
E
E
Q
G
C
Q
-
T
-
L
N
G
L
G
M
M
L
W
Q
G
A
K
A
F
E
I
W
T
H
K
E
M
P
V
D
Y
I
K
E
I
L
-----
5
PsiBlast_PDB
84.77
34%
-48
- C5 -
-
1VI2
1
YDIB_ECOLI
A:
[10-284]
-------
E
L
I
G
L
M
A
Y
P
I
R
H
S
L
S
P
E
M
Q
N
K
A
L
E
K
A
G
L
P
----
F
T
Y
M
A
F
E
V
D
N
D
S
F
P
G
A
I
E
G
L
K
A
L
K
M
R
G
T
G
V
S
M
P
N
K
Q
L
A
C
E
Y
V
D
E
L
T
P
A
A
K
L
V
G
A
I
N
T
I
V
N
-
D
D
G
Y
L
R
G
Y
N
T
D
G
T
G
H
I
R
A
I
K
E
S
--
G
F
--
D
--
I
K
G
K
T
M
V
L
L
G
A
G
G
A
S
T
A
I
G
A
Q
G
A
I
E
G
L
K
E
I
K
L
F
N
R
R
----
D
E
F--
F
D
-
K
A
L
A
F
A
Q
R
V
N
E
N
T
D
C
V
V
T
-
V
T
D
L
A
D
Q
Q
A
F
A
E
A
L
A
S
A
D
I
L
T
N
G
T
K
V
G
M
---
K
PL
E
N
E
-
S
L
V
N
-
D
-
I
S
L
---
L
H
P
G
L
L
V
T
E
C
V
Y
N
P
H
M
T
K
L
L
Q
Q
A
Q
Q
A
G
C
K
-
T
-
I
D
G
Y
G
M
L
L
W
Q
G
A
E
Q
F
T
L
W
T
G
K
D
F
P
L
E
Y
V
K
Q
-------
28
PsiBlast_CBE
84.74
42%
-30
- C5 -
-
3TNL
1
AROE_LISMO
D:
[32-314]
-
R
I
T
G
H
T
E
L
I
G
L
I
A
T
P
I
R
H
S
L
S
P
T
M
H
N
E
A
F
A
K
L
G
L
D
----
Y
V
Y
L
A
F
E
V
G
D
K
E
L
K
D
V
V
Q
G
F
R
A
M
N
L
R
G
W
N
V
S
M
P
N
K
T
N
I
H
K
Y
L
D
K
L
S
P
A
A
E
L
V
G
A
V
N
T
V
V
N
-
D
D
G
V
L
T
G
H
I
T
D
G
T
G
Y
M
R
A
L
--
K
EA
G
H
--
D
--
I
I
G
K
K
M
T
I
C
G
A
G
G
A
A
T
A
I
C
I
Q
A
A
L
D
G
V
K
E
I
S
I
F
N
R
K
DDFY
A
N
---
A
E
-
K
T
---
V
E
K
I
N
S
K
T
D
C
K
A
Q
-
L
F
D
I
E
D
H
E
Q
L
R
K
E
I
A
E
S
V
I
F
T
N
A
T
G
V
G
M
KPF
E
--
G
E
T
-
L
L
P
S
-
A
-
D
M
L
---
R
P
E
-
L
I
V
S
D
V
V
Y
K
P
T
K
T
R
L
L
E
I
A
E
E
Q
G
C
Q
-
T
-
L
N
G
L
G
M
M
L
W
Q
G
A
K
A
F
E
I
W
T
H
K
E
M
P
V
D
Y
I
K
E
I
L
-----
80
HHSearch
84.35
36%
-46
- C5 -
-
3T4E
1
YDIB_SALTY
B:
[28-309]
---
T
A
K
Y
E
L
I
G
L
M
A
Y
P
I
R
H
S
L
S
P
E
M
Q
N
K
A
L
E
K
A
G
L
P
----
Y
T
Y
M
A
F
E
V
D
N
T
T
F
A
S
A
I
E
G
L
K
A
L
K
M
R
G
T
G
V
S
M
P
N
K
Q
L
A
C
E
Y
V
D
E
L
T
P
A
A
K
L
V
G
A
I
N
T
I
V
N
-
D
D
G
Y
L
R
G
Y
N
T
D
G
T
G
H
I
R
A
I
K
-
E
S
-
G
F
--
D
--
M
R
G
K
T
M
V
L
L
G
A
G
G
A
A
T
A
I
G
A
Q
A
A
I
E
G
I
K
E
I
K
L
F
N
R
K
----
D
D
---
F
F
E
K
A
V
A
F
A
K
R
V
N
E
N
T
-
D
C
V
V
T
V
T
D
L
A
D
Q
H
A
F
T
E
A
L
A
S
A
D
I
L
T
N
G
T
K
V
G
M
---
K
--
P
L
E
N
E
S
L
I
G
D
-
V
S
L
---
L
R
P
E
L
L
V
T
E
C
V
Y
N
P
H
M
T
K
L
L
Q
Q
A
Q
Q
A
G
C
K
-
T
-
I
D
G
Y
G
M
L
L
W
Q
G
A
E
Q
F
E
L
W
T
G
K
A
F
P
L
D
Y
V
K
Q
V
M
G
----
4
PsiBlast_PDB
84.01
34%
-44
- C5 -
-
1O9B
1
YDIB_ECOLI
A:
[8-282]
-------
E
L
I
G
L
M
A
Y
P
I
R
H
S
L
S
P
E
M
Q
N
K
A
L
E
K
A
G
L
P
----
F
T
Y
M
A
F
E
V
D
N
D
S
F
P
G
A
I
E
G
L
K
A
L
K
M
R
G
T
G
V
S
M
P
N
K
Q
L
A
C
E
Y
V
D
E
L
T
P
A
A
K
L
V
G
A
I
N
T
I
V
N
-
D
D
G
Y
L
R
G
Y
N
T
D
G
T
G
H
I
R
A
I
K
E
S
--
G
F
--
D
--
I
K
G
K
T
M
V
L
L
G
A
G
G
A
S
T
A
I
G
A
Q
G
A
I
E
G
L
K
E
I
K
L
F
N
R
R
----
D
E
F--
F
D
-
K
A
L
A
F
A
Q
R
V
N
E
N
T
D
C
V
V
T
-
V
T
D
L
A
D
Q
Q
A
F
A
E
A
L
A
S
A
D
I
L
T
N
G
T
K
V
G
M
---
K
PL
E
N
E
-
S
L
V
N
-
D
-
I
S
L
---
L
H
P
G
L
L
V
T
E
C
V
Y
N
P
H
M
T
K
L
L
Q
Q
A
Q
Q
A
G
C
K
-
T
-
I
D
G
Y
G
M
L
L
W
Q
G
A
E
Q
F
T
L
W
T
G
K
D
F
P
L
E
Y
V
K
Q
-------
27
PsiBlast_CBE
83.99
42%
-31
- C5 -
-
3TOZ
1
AROE_LISMO
B:
[32-314]
-
R
I
T
G
H
T
E
L
I
G
L
I
A
T
P
I
R
H
S
L
S
P
T
M
H
N
E
A
F
A
K
L
G
L
D
----
Y
V
Y
L
A
F
E
V
G
D
K
E
L
K
D
V
V
Q
G
F
R
A
M
N
L
R
G
W
N
V
S
M
P
N
K
T
N
I
H
K
Y
L
D
K
L
S
P
A
A
E
L
V
G
A
V
N
T
V
V
N
-
D
D
G
V
L
T
G
H
I
T
D
G
T
G
Y
M
R
A
L
--
K
E
A
G
H
--
D
--
I
I
G
K
K
M
T
I
C
G
A
G
G
A
A
T
A
I
C
I
Q
A
A
L
D
G
V
K
E
I
S
I
F
N
R
K
DDF
Y
A
N
---
A
E
-
K
T
---
V
E
K
I
N
S
K
T
D
C
K
A
Q
-
L
F
D
I
E
D
H
E
Q
L
R
K
E
I
A
E
S
V
I
F
T
N
A
T
G
V
G
M
KPF
E
--
G
E
T
-
L
L
P
S
-
A
-
D
M
L
---
R
P
E
-
L
I
V
S
D
V
V
Y
K
P
T
K
T
R
L
L
E
I
A
E
E
Q
G
C
Q
-
T
-
L
N
G
L
G
M
M
L
W
Q
G
A
K
A
F
E
I
W
T
H
K
E
M
P
V
D
Y
I
K
E
I
L
-----
22
PsiBlast_CBE
83.91
42%
-29
- C5 -
-
3TOZ
1
AROE_LISMO
G:
[32-314]
-
R
I
T
G
H
T
E
L
I
G
L
I
A
T
P
I
R
H
S
L
S
P
T
M
H
N
E
A
F
A
K
L
G
L
D
----
Y
V
Y
L
A
F
E
V
G
D
K
E
L
K
D
V
V
Q
G
F
R
A
M
N
L
R
G
W
N
V
S
M
P
N
K
T
N
I
H
K
Y
L
D
K
L
S
P
A
A
E
L
V
G
A
V
N
T
V
V
N
-
D
D
G
V
L
T
G
H
I
T
D
G
T
G
Y
M
R
A
L
--
K
EA
G
H
--
D
--
I
I
G
K
K
M
T
I
C
G
A
G
G
A
A
T
A
I
C
I
Q
A
A
L
D
G
V
K
E
I
S
I
F
N
R
K
DDFY
A
N
---
A
E
-
K
T
---
V
E
K
I
N
S
K
T
D
C
K
A
Q
-
L
F
D
I
E
D
H
E
Q
L
R
K
E
I
A
E
S
V
I
F
T
N
A
T
G
V
G
M
KPF
E
--
G
E
T
-
L
L
P
S
-
A
-
D
M
L
---
R
P
E
-
L
I
V
S
D
V
V
Y
K
P
T
K
T
R
L
L
E
I
A
E
E
Q
G
C
Q
-
T
-
L
N
G
L
G
M
M
L
W
Q
G
A
K
A
F
E
I
W
T
H
K
E
M
P
V
D
Y
I
K
E
I
L
-----
76
HHSearch
83.30
36%
-46
- C5 -
-
1NPD
1
YDIB_ECOLI
B:
[1-286]
M
D
V
T
A
K
Y
E
L
I
G
L
M
A
Y
P
I
R
H
S
L
S
P
E
M
Q
N
K
A
L
E
K
A
G
L
P
----
F
T
Y
M
A
F
E
V
D
N
D
S
F
P
G
A
I
E
G
L
K
A
L
K
M
R
G
T
G
V
S
M
P
N
K
Q
L
A
C
E
Y
V
D
E
L
T
P
A
A
K
L
V
G
A
I
N
T
I
V
N
-
D
D
G
Y
L
R
G
Y
N
T
D
G
T
G
H
I
R
A
I
K-
E
S-
G
F
--
D
--
I
K
G
K
T
M
V
L
L
G
A
G
G
A
S
T
A
I
G
A
Q
G
A
I
E
G
L
K
E
I
K
L
F
N
R
R
----
D
E
---
F
F
D
K
A
L
A
F
A
Q
R
V
N
E
N
T
-
D
C
V
V
T
V
T
D
L
A
D
Q
Q
A
F
A
E
A
L
A
S
A
D
I
L
T
N
G
T
K
V
G
M
---
K
--
P
L
E
N
E
S
L
V
N
D
-
I
S
L
---
L
H
P
G
L
L
V
T
E
C
V
Y
N
P
H
M
T
K
L
L
Q
Q
A
Q
Q
A
G
C
K
-
T
-
I
D
G
Y
G
M
L
L
W
Q
G
A
E
Q
F
T
L
W
T
G
K
D
F
P
L
E
Y
V
K
Q
V
M
G
F
---
77
HHSearch
83.21
43%
-19
* C5 *
-
3TNL
2
AROE_LISMO
A:
[32-314]
-
R
I
T
G
H
T
E
L
I
G
L
I
A
T
P
I
R
H
S
L
S
P
T
M
H
N
E
A
F
A
K
L
G
L
D
----
Y
V
Y
L
A
F
E
V
G
D
K
E
L
K
D
V
V
Q
G
F
R
A
M
N
L
R
G
W
N
V
S
M
P
N
K
T
N
I
H
K
Y
L
D
K
L
S
P
A
A
E
L
V
G
A
V
N
T
V
V
N
-
D
D
G
V
L
T
G
H
I
T
D
G
T
G
Y
M
R
A
L
K
-
E
A
-
G
H
--
D
--
I
I
G
K
K
M
T
I
C
G
A
G
G
A
A
T
A
I
C
I
Q
A
A
L
D
G
V
K
E
I
S
I
F
N
R
K
----
D
D
F
Y
A
N
A
---
E
K
T
V
E
K
I
N
S
K
T
-
D
C
K
A
Q
L
F
D
I
E
D
H
E
Q
L
R
K
E
I
A
E
S
V
I
F
T
N
A
T
G
V
G
M
---
K
--
P
F
E
G
E
T
L
L
-
P
S
A
D
M
---
L
R
P
E
L
I
V
S
D
V
V
Y
K
P
T
K
T
R
L
L
E
I
A
E
E
Q
G
C
Q
-
T
-
L
N
G
L
G
M
M
L
W
Q
G
A
K
A
F
E
I
W
T
H
K
E
M
P
V
D
Y
I
K
E
I
L
-----
3
PsiBlast_PDB
82.93
34%
-39
- C5 -
-
1NPD
1
YDIB_ECOLI
A:
[8-282]
-------
E
L
I
G
L
M
A
Y
P
I
R
H
S
L
S
P
E
M
Q
N
K
A
L
E
K
A
G
L
P
----
F
T
Y
M
A
F
E
V
D
N
D
S
F
P
G
A
I
E
G
L
K
A
L
K
M
R
G
T
G
V
S
M
P
N
K
Q
L
A
C
E
Y
V
D
E
L
T
P
A
A
K
L
V
G
A
I
N
T
I
V
N
-
D
D
G
Y
L
R
G
Y
N
T
D
G
T
G
H
I
R
A
I
K
E
S
--
G
F
--
D
--
I
K
G
K
T
M
V
L
L
G
A
G
G
A
S
T
A
I
G
A
Q
G
A
I
E
G
L
K
E
I
K
L
F
N
R
R
----
D
E
F--
F
D
-
K
A
L
A
F
A
Q
R
V
N
E
N
T
D
C
V
V
T
-
V
T
D
L
A
D
Q
Q
A
F
A
E
A
L
A
S
A
D
I
L
T
N
G
T
K
V
G
M
---
K
PL
E
N
E
-
S
L
V
N
-
D
-
I
S
L
---
L
H
P
G
L
L
V
T
E
C
V
Y
N
P
H
M
T
K
L
L
Q
Q
A
Q
Q
A
G
C
K
-
T
-
I
D
G
Y
G
M
L
L
W
Q
G
A
E
Q
F
T
L
W
T
G
K
D
F
P
L
E
Y
V
K
Q
-------
7
PsiBlast_PDB
81.82
35%
-62
- C5 -
-
2HK7
-
AROE_AQUAE
A:
[2-256]
--
I
N
A
Q
T
Q
L
Y
G
V
I
G
F
P
V
K
H
S
L
S
P
V
F
Q
N
A
L
I
R
Y
A
G
L
N
----
A
V
Y
L
A
F
E
I
N
P
E
E
L
K
K
A
F
E
G
F
K
A
L
K
V
K
G
I
N
V
T
V
P
F
K
E
E
I
I
P
L
L
D
Y
V
E
D
T
A
K
E
I
G
A
V
N
T
V
K
F
-
E
N
G
K
A
Y
G
Y
N
T
D
W
I
G
F
L
K
S
L
--
K
--
S
L
--
I
PE
V
K
E
K
S
I
L
V
L
G
A
G
G
A
S
R
A
V
I
Y
A
L
V
K
E
G
A
---
K
V
F
L
W
N
----
R
T
---
K
E
-
K
A
I
K
L
A
Q
K
F
------------
P
L
E
V
V
N
S
P
E
E
V
I
D
K
V
Q
V
I
V
N
T
T
S
V
G
L
---
K
--
D
E
D
-
P
E
I
F
-
N
-
Y
D
L
---
I
K
K
D
H
V
V
V
D
I
I
Y
K
--
E
T
K
L
L
K
K
A
K
E
K
G
A
K
-
L
-
L
D
G
L
P
M
L
L
W
Q
G
I
E
A
F
K
I
W
N
G
C
E
V
P
-------------
6
PsiBlast_PDB
81.73
36%
-39
- C5 -
-
3T4E
1
YDIB_SALTY
A:
[32-308]
-------
E
L
I
G
L
M
A
Y
P
I
R
H
S
L
S
P
E
M
Q
N
K
A
L
E
K
A
G
L
P
----
Y
T
Y
M
A
F
E
V
D
N
T
T
F
A
S
A
I
E
G
L
K
A
L
K
M
R
G
T
G
V
S
M
P
N
K
Q
L
A
C
E
Y
V
D
E
L
T
P
A
A
K
L
V
G
A
I
N
T
I
V
N
-
D
D
G
Y
L
R
G
Y
N
T
D
G
T
G
H
I
R
A
I
K
E
S
--
G
F
--
D
--
M
R
G
K
T
M
V
L
L
G
A
G
G
A
A
T
A
I
G
A
Q
A
A
I
E
G
I
K
E
I
K
L
F
N
R
K
----
D
D
F--
F
E
-
K
A
V
A
F
A
K
R
V
N
E
N
T
D
C
V
V
T
-
V
T
D
L
A
D
Q
H
A
F
T
E
A
L
A
S
A
D
I
L
T
N
G
T
K
V
G
M
KPL
E
--
N
E
S
-
L
I
G
D
-
V
-
S
L
L
---
R
P
E
-
L
L
V
T
E
C
V
Y
N
P
H
M
T
K
L
L
Q
Q
A
Q
Q
A
G
C
K
-
T
-
I
D
G
Y
G
M
L
L
W
Q
G
A
E
Q
F
E
L
W
T
G
K
A
F
P
L
D
Y
V
K
Q
V
M
-----
32
PsiBlast_CBE
81.51
35%
-64
- C5 -
-
2HK9
2
AROE_AQUAE
D:
[8-262]
--
I
N
A
Q
T
Q
L
Y
G
V
I
G
F
P
V
K
H
S
L
S
P
V
F
Q
N
A
L
I
R
Y
A
G
L
N
----
A
V
Y
L
A
F
E
I
N
P
E
E
L
K
K
A
F
E
G
F
K
A
L
K
V
K
G
I
N
V
T
V
P
F
K
E
E
I
I
P
L
L
D
Y
V
E
D
T
A
K
E
I
G
A
V
N
T
V
K
F
-
E
N
G
K
A
Y
G
Y
N
T
D
W
I
G
F
L
K
S
L
--
K
--
S
L
--
I
PE
V
K
E
K
S
I
L
V
L
G
A
G
G
A
S
R
A
V
I
Y
A
L
V
K
E
G
A
---
K
V
F
L
W
N
----
R
T
---
K
E
-
K
A
I
K
L
A
Q
K
F
------------
P
L
E
V
V
N
S
P
E
E
V
I
D
K
V
Q
V
I
V
N
T
T
S
V
G
L
---
K
--
D
E
D
-
P
E
I
F
-
N
-
Y
D
L
---
I
K
K
D
H
V
V
V
D
I
I
Y
K
--
E
T
K
L
L
K
K
A
K
E
K
G
A
K
-
L
-
L
D
G
L
P
M
L
L
W
Q
G
I
E
A
F
K
I
W
N
G
C
E
V
P
-------------
9
PsiBlast_PDB
81.38
35%
-66
- C5 -
-
2HK9
3
AROE_AQUAE
A:
[8-262]
--
I
N
A
Q
T
Q
L
Y
G
V
I
G
F
P
V
K
H
S
L
S
P
V
F
Q
N
A
L
I
R
Y
A
G
L
N
----
A
V
Y
L
A
F
E
I
N
P
E
E
L
K
K
A
F
E
G
F
K
A
L
K
V
K
G
I
N
V
T
V
P
F
K
E
E
I
I
P
L
L
D
Y
V
E
D
T
A
K
E
I
G
A
V
N
T
V
K
F
-
E
N
G
K
A
Y
G
Y
N
T
D
W
I
G
F
L
K
S
L
--
K
--
S
L
--
I
PE
V
K
E
K
S
I
L
V
L
G
A
G
G
A
S
R
A
V
I
Y
A
L
V
K
E
G
A
---
K
V
F
L
W
N
----
R
T
---
K
E
-
K
A
I
K
L
A
Q
K
F
------------
P
L
E
V
V
N
S
P
E
E
V
I
D
K
V
Q
V
I
V
N
T
T
S
V
G
L
---
K
--
D
E
D
-
P
E
I
F
-
N
-
Y
D
L
---
I
K
K
D
H
V
V
V
D
I
I
Y
K
--
E
T
K
L
L
K
K
A
K
E
K
G
A
K
-
L
-
L
D
G
L
P
M
L
L
W
Q
G
I
E
A
F
K
I
W
N
G
C
E
V
P
-------------
34
PsiBlast_CBE
80.35
35%
-61
- C5 -
-
2HK9
2
AROE_AQUAE
B:
[8-262]
--
I
N
A
Q
T
Q
L
Y
G
V
I
G
F
P
V
K
H
S
L
S
P
V
F
Q
N
A
L
I
R
Y
A
G
L
N
----
A
V
Y
L
A
F
E
I
N
P
E
E
L
K
K
A
F
E
G
F
K
A
L
K
V
K
G
I
N
V
T
V
P
F
K
E
E
I
I
P
L
L
D
Y
V
E
D
T
A
K
E
I
G
A
V
N
T
V
K
F
-
E
N
G
K
A
Y
G
Y
N
T
D
W
I
G
F
L
K
S
L
--
K
--
S
L
--
I
PE
V
K
E
K
S
I
L
V
L
G
A
G
G
A
S
R
A
V
I
Y
A
L
V
K
E
G
A
---
K
V
F
L
W
N
----
R
T
---
K
E
-
K
A
I
K
L
A
Q
K
F
------------
P
L
E
V
V
N
S
P
E
E
V
I
D
K
V
Q
V
I
V
N
T
T
S
V
G
L
---
K
--
D
E
D
-
P
E
I
F
-
N
-
Y
D
L
---
I
K
K
D
H
V
V
V
D
I
I
Y
K
--
E
T
K
L
L
K
K
A
K
E
K
G
A
K
-
L
-
L
D
G
L
P
M
L
L
W
Q
G
I
E
A
F
K
I
W
N
G
C
E
V
P
-------------
40
PsiBlast_CBE
80.14
36%
-115
- C5 -
-
2D5C
1
AROE_THET8
B:
[5-245]
----------
A
V
L
G
H
P
V
A
H
S
L
S
P
A
M
H
A
F
A
L
E
S
L
G
L
E
----
G
S
Y
E
A
W
D
T
P
L
E
A
L
P
G
R
L
K
E
V
R
R
-
A
F
R
G
V
N
L
T
L
P
L
K
E
A
A
L
A
H
L
D
W
V
S
P
E
A
Q
R
I
G
A
V
N
T
V
L
Q
-
V
E
G
R
L
F
G
F
N
T
D
A
P
G
F
L
E
A
L
--
K
--
A
G
--
G
--
I
P
L
K
G
P
A
L
V
L
G
A
G
G
A
G
R
A
V
A
F
A
L
R
E
A
G
L
E
V
W
V
W
N
R
T
----
P
Q
---
R
A
-
L
A
------
L
A
E
E
F
G
L
R
A
---
V
P
L
E
-----
K
A
R
--
E
A
R
L
L
V
N
A
T
R
V
G
L
--------
A
-
S
P
L
P
-
A
-
E
L
----
F
P
E
E
G
A
A
V
D
L
V
Y
R
P
L
W
T
R
F
L
R
E
A
K
A
K
G
L
K
-
V
-
Q
T
G
L
P
M
L
A
W
Q
G
A
L
A
F
R
L
W
T
G
-----------------
16
PsiBlast_PDB
77.34
36%
-90
- C5 -
-
2D5C
1
AROE_THET8
A:
[5-245]
----------
A
V
L
G
H
P
V
A
H
S
L
S
P
A
M
H
A
F
A
L
E
S
L
G
L
E
----
G
S
Y
E
A
W
D
T
P
L
E
A
L
P
G
R
L
K
E
V
R
R
-
A
F
R
G
V
N
L
T
L
P
L
K
E
A
A
L
A
H
L
D
W
V
S
P
E
A
Q
R
I
G
A
V
N
T
V
L
Q
-
V
E
G
R
L
F
G
F
N
T
D
A
P
G
F
L
E
A
L
--
K
--
A
G
--
G
--
I
P
L
K
G
P
A
L
V
L
G
A
G
G
A
G
R
A
V
A
F
A
L
R
E
A
G
L
E
V
W
V
W
N
R
T
----
P
Q
---
R
A
-
L
A
------
L
A
E
E
F
G
L
R
A
---
V
P
L
E
-----
K
A
R
--
E
A
R
L
L
V
N
A
T
R
V
G
L
E--
D
--
P
S
A
-
S
P
L
P
-
A
-
E
L
----
F
P
E
E
G
A
A
V
D
L
V
Y
R
P
L
W
T
R
F
L
R
E
A
K
A
K
G
L
K
-
V
-
Q
T
G
L
P
M
L
A
W
Q
G
A
L
A
F
R
L
W
T
G
-----------------
17
PsiBlast_PDB
76.23
36%
-88
- C5 -
-
2EV9
2
AROE_THET8
A:
[5-245]
----------
A
V
L
G
H
P
V
A
H
S
L
S
P
A
M
H
A
F
A
L
E
S
L
G
L
E
----
G
S
Y
E
A
W
D
T
P
L
E
A
L
P
G
R
L
K
E
V
R
R
-
A
F
R
G
V
N
L
T
L
P
L
K
E
A
A
L
A
H
L
D
W
V
S
P
E
A
Q
R
I
G
A
V
N
T
V
L
Q
-
V
E
G
R
L
F
G
F
N
T
D
A
P
G
F
L
E
A
L
--
K
--
A
G
--
G
--
I
P
L
K
G
P
A
L
V
L
G
A
G
G
A
G
R
A
V
A
F
A
L
R
E
A
G
L
E
V
W
V
W
N
R
T
----
P
Q
---
R
A
-
L
A
------
L
A
E
E
F
G
L
R
A
---
V
P
L
E
-----
K
A
R
--
E
A
R
L
L
V
N
A
T
R
V
G
L
E--
D
--
P
S
A
-
S
P
L
P
-
A
-
E
L
----
F
P
E
E
G
A
A
V
D
L
V
Y
R
P
L
W
T
R
F
L
R
E
A
K
A
K
G
L
K
-
V
-
Q
T
G
L
P
M
L
A
W
Q
G
A
L
A
F
R
L
W
T
G
-----------------
33
PsiBlast_CBE
75.86
35%
-53
- C5 -
-
2HK9
2
AROE_AQUAE
C:
[8-262]
--
I
N
A
Q
T
Q
L
Y
G
V
I
G
F
P
V
K
H
S
L
S
P
V
F
Q
N
A
L
I
R
Y
A
G
L
N
----
A
V
Y
L
A
F
E
I
N
P
E
E
L
K
K
A
F
E
G
F
K
A
L
K
V
K
G
I
N
V
T
V
P
F
K
E
E
I
I
P
L
L
D
Y
V
E
D
T
A
K
E
I
G
A
V
N
T
V
K
F
-
E
N
G
K
A
Y
G
Y
N
T
D
W
I
G
F
L
K
S
L
--
K
--
S
L
--
I
PE
V
K
E
K
S
I
L
V
L
G
A
G
G
A
S
R
A
V
I
Y
A
L
V
K
E
G
A
---
K
V
F
L
W
N
----
R
T
---
K
E
-
K
A
I
K
L
A
Q
K
F
------------
P
L
E
V
V
N
S
P
E
E
V
I
D
K
V
Q
V
I
V
N
T
T
S
V
G
L
---
K
--
D
E
D
-
P
E
I
F
-
N
-
Y
D
L
---
I
K
K
D
H
V
V
V
D
I
I
Y
K
--
E
T
K
L
L
K
K
A
K
E
K
G
A
K
-
L
-
L
D
G
L
P
M
L
L
W
Q
G
I
E
A
F
K
I
W
N
G
C
E
V
P
-------------
39
PsiBlast_CBE
75.72
36%
-90
- C5 -
-
2EV9
1
AROE_THET8
B:
[5-245]
----------
A
V
L
G
H
P
V
A
H
S
L
S
P
A
M
H
A
F
A
L
E
S
L
G
L
E
----
G
S
Y
E
A
W
D
T
P
L
E
A
L
P
G
R
L
K
E
V
R
R
-
A
F
R
G
V
N
L
T
L
P
L
K
E
A
A
L
A
H
L
D
W
V
S
P
E
A
Q
R
I
G
A
V
N
T
V
L
Q
-
V
E
G
R
L
F
G
F
N
T
D
A
P
G
F
L
E
A
L
--
K
--
A
G
--
G
--
I
P
L
K
G
P
A
L
V
L
G
A
G
G
A
G
R
A
V
A
F
A
L
R
E
A
G
L
E
V
W
V
W
N
R
T
----
P
Q
---
R
A
-
L
A
------
L
A
E
E
F
G
L
R
A
---
V
P
L
E
-----
K
A
R
--
E
A
R
L
L
V
N
A
T
R
V
G
L
E--
D
--
P
S
A
-
S
P
L
P
-
A
-
E
L
----
F
P
E
E
G
A
A
V
D
L
V
Y
R
P
L
W
T
R
F
L
R
E
A
K
A
K
G
L
K
-
V
-
Q
T
G
L
P
M
L
A
W
Q
G
A
L
A
F
R
L
W
T
G
-----------------
18
PsiBlast_PDB
73.87
34%
-55
- C5 -
-
1NYT
2
AROE_ECOLI
A:
[5-269]
----------
A
V
F
G
N
P
I
A
H
S
K
S
P
F
I
H
Q
Q
F
A
Q
Q
L
N
I
E
----
H
P
Y
G
R
V
L
A
P
I
N
D
F
I
N
T
L
N
A
F
F
S
A
G
G
K
G
A
N
V
T
V
P
F
K
E
E
A
F
A
R
A
D
E
L
T
E
R
A
A
L
A
G
A
V
N
T
L
M
R
L
E
D
G
R
L
L
G
D
N
T
D
G
V
G
L
L
S
D
L
--
E
R
L
S
F
--
I
--
R
P
G
L
R
I
L
L
I
G
A
G
G
A
S
R
G
V
L
L
-
P
L
L
S
L
D
C
A
V
T
I
T
N
R
T
----
V
S
---
R
A
-
E
E
---
L
A
K
L
F
A
H
T
G
-------
S
I
Q
A
L
S
M
D
E
L
E
G
H
E
F
D
L
I
I
N
A
T
S
S
G
I
---
S
--
G
D
I
-
P
A
I
P
-
S
-
S
L
I
---
H
P
-
G
I
Y
C
Y
D
M
F
Y
Q
K
G
K
T
P
F
L
A
W
C
E
Q
R
G
S
K
-
R
N
A
D
G
L
G
M
L
V
A
Q
A
A
H
A
F
L
L
W
H
G
V
L
P
D
V
E
P
V
I
K
Q
L
Q
E
E
--
94
HHSearch
72.73
33%
-56
- C5 -
-
2EV9
1
AROE_THET8
B:
[1-261]
------
M
L
R
F
A
V
L
G
H
P
V
A
H
S
L
S
P
A
M
H
A
F
A
L
E
S
L
G
L
E
----
G
S
Y
E
A
W
D
T
P
L
E
A
L
P
G
R
L
K
E
V
R
-
R
A
F
R
G
V
N
L
T
L
P
L
K
E
A
A
L
A
H
L
D
W
V
S
P
E
A
Q
R
I
G
A
V
N
T
V
L
Q
-
V
E
G
R
L
F
G
F
N
T
D
A
P
G
F
L
E
A
L
K-
A
G-
G
I
--
P
--
L
K
-
G
P
A
L
V
L
G
A
G
G
A
G
R
A
V
A
F
A
L
R
E
A
G
L
-
E
V
W
V
W
N
R
T
----
P
Q
---
R
A
---
L
A
L
A
E
E
F
G
L
R
----------
A
V
P
----
L
E
K
A
R
E
A
R
L
L
V
N
A
T
R
V
G
L
---
E
--
D
P
S
A
S
P
L
--
P
-
A
E
L
---
F
P
E
E
G
A
A
V
D
L
V
Y
R
P
L
W
T
R
F
L
R
E
A
K
A
K
G
L
K
-
V
-
Q
T
G
L
P
M
L
A
W
Q
G
A
L
A
F
R
L
W
T
G
L
L
P
D
P
S
G
M
E
E
A
A
R
R
A
L
-
93
HHSearch
72.46
33%
-56
- C5 -
-
2D5C
1
AROE_THET8
A:
[1-261]
------
M
L
R
F
A
V
L
G
H
P
V
A
H
S
L
S
P
A
M
H
A
F
A
L
E
S
L
G
L
E
----
G
S
Y
E
A
W
D
T
P
L
E
A
L
P
G
R
L
K
E
V
R
-
R
A
F
R
G
V
N
L
T
L
P
L
K
E
A
A
L
A
H
L
D
W
V
S
P
E
A
Q
R
I
G
A
V
N
T
V
L
Q
-
V
E
G
R
L
F
G
F
N
T
D
A
P
G
F
L
E
A
L
K
-
A
G
-
G
I
--
P
--
L
K
-
G
P
A
L
V
L
G
A
G
G
A
G
R
A
V
A
F
A
L
R
E
A
G
L
-
E
V
W
V
W
N
R
T
----
P
Q
---
R
A
---
L
A
L
A
E
E
F
G
L
R
----------
A
V
P
----
L
E
K
A
R
E
A
R
L
L
V
N
A
T
R
V
G
L
---
E
--
D
P
S
A
S
P
L
--
P
-
A
E
L
---
F
P
E
E
G
A
A
V
D
L
V
Y
R
P
L
W
T
R
F
L
R
E
A
K
A
K
G
L
K
-
V
-
Q
T
G
L
P
M
L
A
W
Q
G
A
L
A
F
R
L
W
T
G
L
L
P
D
P
S
G
M
E
E
A
A
R
R
A
L
-
12
PsiBlast_PDB
71.81
34%
-52
- C5 -
-
3DOO
1
AROE_STAEQ
A:
[4-251]
----------
A
V
I
G
N
P
I
S
H
S
L
S
P
L
M
H
H
A
N
F
Q
S
L
N
L
E
----
N
T
Y
E
A
I
N
V
P
V
N
Q
F
Q
D
I
K
K
I
I
S
E
K
S
I
D
G
F
N
V
T
I
P
H
K
E
R
I
I
P
Y
L
D
D
I
N
E
Q
A
K
S
V
G
A
V
N
T
V
L
V
-
K
D
G
K
W
I
G
Y
N
T
D
G
I
G
Y
V
N
G
L
--
K
--
Q
I
Y
E
G
--
I
E
D
A
Y
I
L
I
L
G
A
G
G
A
S
K
G
I
A
N
E
--
L
Y
K
I
V
R
P
T
L
T
V
A
N
----
R
T
---
M
S
-
R
F
N
N
W
S
L
N
I
N
-----
K
I
N
-
L
------
S
H
A
E
S
H
L
D
E
F
D
I
I
I
N
T
T
P
---------------
V
I
-
S
-
L
N
R
---
L
A
S
H
T
L
V
S
D
I
V
Y
N
P
Y
K
T
P
I
L
I
E
A
E
Q
R
G
N
P
-
I
-
Y
N
G
L
D
M
F
V
H
Q
G
A
E
S
F
K
I
W
T
N
L
E
---------------
53
PsiBlast_CBE
70.69
32%
-42
- C5 -
-
3PGJ
1
AROE_VIBCH
D:
[33-294]
----------
A
V
F
G
N
P
I
N
H
S
K
S
P
F
I
H
T
L
F
A
R
Q
T
Q
Q
S
----
M
I
Y
T
A
Q
C
V
P
V
D
G
F
T
E
A
A
K
H
F
F
A
Q
G
G
R
G
C
N
V
T
V
P
F
K
E
E
A
Y
R
F
A
D
R
L
T
E
R
A
R
L
A
G
A
V
N
T
L
K
K
L
D
D
G
E
I
L
G
D
N
T
D
G
E
G
L
V
Q
D
L
LA
Q
--
Q
V
--
L
--
L
K
G
A
T
I
L
L
I
G
A
G
G
A
A
R
G
V
L
K
P
L
L
D
Q
Q
P
A
S
I
T
V
T
N
R
T
----
F
A
---
K
A
-
E
Q
---
L
A
E
L
V
A
A
Y
G
-
E
V
K
-
A
Q
A
F
E
Q
L
K
Q
------
S
Y
D
V
I
I
N
S
T
S
A
S
L
---
D
--
G
E
--
L
P
A
I
-
D
-
P
V
I
---
F
S
S
R
S
V
C
Y
D
M
M
Y
G
K
G
Y
T
V
F
N
Q
W
A
R
Q
H
G
C
A
Q
A
-
I
D
G
L
G
M
L
V
G
Q
A
A
E
S
F
M
L
W
R
G
L
R
P
G
T
K
Q
I
L
R
E
L
-----
54
PsiBlast_CBE
69.60
32%
-44
- C5 -
-
3PGJ
1
AROE_VIBCH
C:
[33-294]
----------
A
V
F
G
N
P
I
N
H
S
K
S
P
F
I
H
T
L
F
A
R
Q
T
Q
Q
S
----
M
I
Y
T
A
Q
C
V
P
V
D
G
F
T
E
A
A
K
H
F
F
A
Q
G
G
R
G
C
N
V
T
V
P
F
K
E
E
A
Y
R
F
A
D
R
L
T
E
R
A
R
L
A
G
A
V
N
T
L
K
K
L
D
D
G
E
I
L
G
D
N
T
D
G
E
G
L
V
Q
D
L
L
A
Q
--
Q
V
--
L
--
L
K
G
A
T
I
L
L
I
G
A
G
G
A
A
R
G
V
L
K
P
L
L
D
Q
Q
P
A
S
I
T
V
T
N
R
T
----
F
A
---
K
A
-
E
Q
---
L
A
E
L
V
A
A
Y
G
-
E
V
K
-
A
Q
A
F
E
Q
L
K
Q
------
S
Y
D
V
I
I
N
S
T
S
--------------
P
A
I
-
D
-
P
V
I
---
F
S
S
R
S
V
C
Y
D
M
M
Y
G
K
G
Y
T
V
F
N
Q
W
A
R
Q
H
G
C
A
Q
A
-
I
D
G
L
G
M
L
V
G
Q
A
A
E
S
F
M
L
W
R
G
L
R
P
G
T
K
Q
I
L
R
E
L
-----
55
PsiBlast_CBE
68.98
32%
-38
- C5 -
-
3PGJ
1
AROE_VIBCH
B:
[33-294]
----------
A
V
F
G
---
N
H
S
K
S
P
F
I
H
T
L
F
A
R
Q
T
Q
Q
S
----
M
I
Y
T
A
Q
C
V
P
V
D
G
F
T
E
A
A
K
H
F
F
A
Q
G
G
R
G
C
N
V
T
V
P
F
K
E
E
A
Y
R
F
A
D
R
L
T
E
R
A
R
L
A
G
A
V
N
T
L
K
K
L
D
D
G
E
I
L
G
D
N
T
D
G
E
G
L
V
Q
D
L
L
A
Q
--
Q
V
--
L
--
L
K
G
A
T
I
L
L
I
G
A
G
G
A
A
R
G
V
L
K
P
L
L
D
Q
Q
P
A
S
I
T
V
T
N
R
T
----
F
A
---
K
A
-
E
Q
---
L
A
E
L
V
A
A
Y
G
-
E
V
K
-
A
Q
A
F
E
Q
L
K
Q
------
S
Y
D
V
I
I
N
S
T
S
A
S
L
---
D
--
G
E
--
L
P
A
I
-
D
-
P
V
I
---
F
S
S
R
S
V
C
Y
D
M
M
Y
G
K
G
Y
T
V
F
N
Q
W
A
R
Q
H
G
C
A
Q
A
-
I
D
G
L
G
M
L
V
G
Q
A
A
E
S
F
M
L
W
R
G
L
R
P
G
T
K
Q
I
L
R
E
L
-----
56
PsiBlast_CBE
68.82
32%
-43
- C5 -
-
3PGJ
1
AROE_VIBCH
A:
[33-294]
----------
A
V
F
G
N
P
I
N
H
S
K
S
P
F
I
H
T
L
F
A
R
Q
T
Q
Q
S
----
M
I
Y
T
A
Q
C
V
P
V
D
G
F
T
E
A
A
K
H
F
F
A
Q
G
G
R
G
C
N
V
T
V
P
F
K
E
E
A
Y
R
F
A
D
R
L
T
E
R
A
R
L
A
G
A
V
N
T
L
K
K
L
D
D
G
E
I
L
G
D
N
T
D
G
E
G
L
V
Q
D
L
L
A
Q
--
Q
V
--
L
--
L
K
G
A
T
I
L
L
I
G
A
G
G
A
A
R
G
V
L
K
P
L
L
D
Q
Q
P
A
S
I
T
V
T
N
R
T
----
F
A
---
K
A
-
E
Q
---
L
A
E
L
V
A
A
Y
G
-
E
V
K
-
A
Q
A
F
E
Q
L
K
Q
------
S
Y
D
V
I
I
N
S
T
S
A
S
L
---
D
--
G
E
--
L
P
A
I
-
D
-
P
V
I
---
F
S
S
R
S
V
C
Y
D
M
M
Y
G
K
G
Y
T
V
F
N
Q
W
A
R
Q
H
G
C
A
Q
A
-
I
D
G
L
G
M
L
V
G
Q
A
A
E
S
F
M
L
W
R
G
L
R
P
G
T
K
Q
I
L
R
E
L
-----
61
PsiBlast_CBE
68.52
31%
2
- C5 -
-
3PHI
2
AROE_HELPY
A:
[1-257]
M
K
L
K
S
F
----
G
V
F
G
N
P
I
K
H
S
K
S
P
L
I
H
N
A
C
F
L
T
F
Q
K
E
LR
F
L
G
H
Y
H
P
I
L
L
P
L
E
S
H
I
K
S
--
E
F
L
H
L
G
L
S
G
A
N
V
T
L
P
F
K
E
R
A
F
Q
V
C
D
K
I
K
G
I
A
L
E
C
G
A
V
N
T
L
V
L
-
E
N
D
E
L
V
G
Y
N
T
D
A
L
G
F
Y
L
S
L
--
K
---------
Y
--
Q
N
A
L
I
L
G
A
G
G
S
A
K
A
L
A
C
E
L
K
K
Q
G
L
-
Q
V
S
V
L
N
R
S
-------------
S
R
G
-
L
D
F
F
Q
R
---
L
G
C
D
--
C
F
M
E
------
P
P
K
S
A
F
D
L
I
I
N
A
T
S
A
S
L
---
H
--
N
E
L
--
P
L
N
-
K
-
E
V
L
K
G
Y
F
K
E
G
K
L
A
Y
D
L
A
Y
G
-
F
L
T
P
F
L
S
L
A
K
E
L
K
T
P
-
F
-
Q
D
G
K
D
M
L
I
Y
Q
A
A
L
S
F
E
K
F
S
A
S
Q
I
P
Y
S
K
A
F
E
-------
64
PsiBlast_CBE
68.41
31%
-3
- C5 -
-
4FR5
1
AROE_HELPY
B:
[1-257]
M
K
L
K
S
F
----
G
V
F
G
N
P
I
K
H
S
K
S
P
L
I
H
N
A
C
F
L
T
F
Q
K
E
LRFL
G
H
Y
H
P
I
L
L
P
L
E
S
H
I
K
S
--
E
F
L
H
L
G
L
S
G
A
N
V
T
L
P
F
K
E
R
A
F
Q
V
C
D
K
I
K
G
I
A
L
E
C
G
A
V
N
T
L
V
L
-
E
N
D
E
L
V
G
Y
N
T
D
A
L
G
F
Y
L
S
L
--
K
--
Q
K
--
N
--
Y
--
Q
N
A
L
I
L
G
A
G
G
S
A
K
A
L
A
C
E
L
K
K
Q
G
L
-
Q
V
S
V
L
N
R
S
-------------
S
R
G
-
L
D
F
F
Q
R
---
L
G
C
D
--
C
F
M
E
------
P
P
K
S
A
F
D
L
I
I
N
A
T
S
A
S
L
---
H
--
N
E
L
--
P
L
N
-
K
-
E
V
L
KGY
F
K
E
G
K
L
A
Y
D
L
A
-
S
G
F
L
T
P
F
L
S
L
A
K
E
L
K
T
P
-
F
-
Q
D
G
K
D
M
L
I
Y
Q
A
A
L
S
F
E
K
F
S
A
S
Q
I
P
Y
S
K
A
F
E
-------
63
PsiBlast_CBE
67.88
31%
-6
- C5 -
-
4FOS
1
AROE_HELPY
A:
[1-257]
M
K
L
K
S
F
----
G
V
F
G
N
P
I
K
H
S
K
S
P
L
I
H
N
A
C
F
L
T
F
Q
K
E
LR
F
L
G
H
Y
H
P
I
L
L
P
L
E
S
H
I
K
S
--
E
F
L
H
L
G
L
S
G
A
N
V
T
L
P
F
K
E
R
A
F
Q
V
C
D
K
I
K
G
I
A
L
E
C
G
A
V
N
T
L
V
L
-
E
N
D
E
L
V
G
Y
N
T
D
A
L
G
F
Y
L
S
L
--
K
--
Q
K
--
N
--
Y
--
Q
N
A
L
I
L
G
A
G
G
S
A
K
A
L
A
C
E
L
K
K
Q
G
L
-
Q
V
S
V
L
N
R
S
-------------
S
R
G
-
L
D
F
F
Q
R
---
L
G
C
D
--
C
F
M
E
------
P
P
K
S
A
F
D
L
I
I
N
A
T
S
A
S
L
---
H
--
N
E
L
--
P
L
N
-
K
-
E
V
L
K
G
Y
F
K
E
G
K
L
A
Y
D
L
A
Y
G
-
F
L
T
P
F
L
S
L
A
K
E
L
K
T
P
-
F
-
Q
D
G
K
D
M
L
I
Y
A
A
A
L
S
F
E
K
F
S
A
S
Q
I
P
Y
S
K
A
F
E
-------
51
PsiBlast_CBE
67.88
32%
-38
- C5 -
-
3SEF
2
AROE_VIBCH
B:
[33-294]
----------
A
V
F
G
---
N
H
S
K
S
P
F
I
H
T
L
F
A
R
Q
T
Q
Q
S
----
M
I
Y
T
A
Q
C
V
P
V
D
G
F
T
E
A
A
K
H
F
F
A
Q
G
G
R
G
C
N
V
T
V
P
F
K
E
E
A
Y
R
F
A
D
R
L
T
E
R
A
R
L
A
G
A
V
N
T
L
K
K
L
D
D
G
E
I
L
G
D
N
T
D
G
E
G
L
V
Q
D
L
L
A
Q
--
Q
V
--
L
--
L
K
G
A
T
I
L
L
I
G
A
G
G
A
A
R
G
V
L
K
P
L
L
D
Q
Q
P
A
S
I
T
V
T
N
R
T
----
F
A
---
K
A
-
E
Q
---
L
A
E
L
V
A
A
Y
G
-
E
V
K
-
A
Q
A
F
E
Q
L
K
Q
------
S
Y
D
V
I
I
N
S
T
S
A
S
L
---
D
--
G
E
--
L
P
A
I
-
D
-
P
V
I
---
F
S
S
R
S
V
C
Y
D
M
M
Y
G
K
G
Y
T
V
F
N
Q
W
A
R
Q
H
G
C
A
Q
A
-
I
D
G
L
G
M
L
V
G
Q
A
A
E
S
F
M
L
W
R
G
L
R
P
G
T
K
Q
I
L
R
E
L
-----
62
PsiBlast_CBE
67.75
31%
-7
- C5 -
-
3PHH
1
AROE_HELPY
A:
[1-257]
M
K
L
K
S
F
----
G
V
F
G
N
P
I
K
H
S
K
S
P
L
I
H
N
A
C
F
L
T
F
Q
K
E
LR
F
L
G
H
Y
H
P
I
L
L
P
L
E
S
H
I
K
S
--
E
F
L
H
L
G
L
S
G
A
N
V
T
L
P
F
K
E
R
A
F
Q
V
C
D
K
I
K
G
I
A
L
E
C
G
A
V
N
T
L
V
L
-
E
N
D
E
L
V
G
Y
N
T
D
A
L
G
F
Y
L
S
L
--
K
---------
Y
--
Q
N
A
L
I
L
G
A
G
G
S
A
K
A
L
A
C
E
L
K
K
Q
G
L
-
Q
V
S
V
L
N
R
S
-------------
S
R
G
-
L
D
F
F
Q
R
---
L
G
C
D
--
C
F
M
E
------
P
P
K
S
A
F
D
L
I
I
N
A
T
S
A
S
L
---
H
--
N
E
L
--
P
L
N
-
K
-
E
V
L
K
G
Y
F
K
E
G
K
L
A
Y
D
L
A
Y
G
-
F
L
T
P
F
L
S
L
A
K
E
L
K
T
P
-
F
-
Q
D
G
K
D
M
L
I
Y
Q
A
A
L
S
F
E
K
F
S
A
S
Q
I
P
Y
S
K
A
F
E
-------
60
PsiBlast_CBE
67.21
31%
0
- C5 -
-
3PHI
2
AROE_HELPY
B:
[1-257]
M
K
L
K
S
F
----
G
V
F
G
N
P
I
K
H
S
K
S
P
L
I
H
N
A
C
F
L
T
F
Q
K
E
LRFL
G
H
Y
H
P
I
L
L
P
L
E
S
H
I
K
S
--
E
F
L
H
L
G
L
S
G
A
N
V
T
L
P
F
K
E
R
A
F
Q
V
C
D
K
I
K
G
I
A
L
E
C
G
A
V
N
T
L
V
L
-
E
N
D
E
L
V
G
Y
N
T
D
A
L
G
F
Y
L
S
L
--
K
---------
Y
--
Q
N
A
L
I
L
G
A
G
G
S
A
K
A
L
A
C
E
L
K
K
Q
G
L
-
Q
V
S
V
L
N
R
S
-------------
S
R
G
-
L
D
F
F
Q
R
---
L
G
C
D
--
C
F
M
E
------
P
P
K
S
A
F
D
L
I
I
N
A
T
S
A
S
L
---
H
--
N
E
L
--
P
L
N
-
K
-
E
V
L
KGY
F
K
E
G
K
L
A
Y
D
L
A
Y
G
-
F
L
T
P
F
L
S
L
A
K
E
L
K
T
P
-
F
-
Q
D
G
K
D
M
L
I
Y
Q
A
A
L
S
F
E
K
F
S
A
S
Q
I
P
Y
S
K
A
F
E
-------
67
PsiBlast_CBE
66.93
31%
-2
- C5 -
-
4FQ8
1
AROE_HELPY
A:
[1-257]
M
K
L
K
S
F
----
G
V
F
G
N
P
I
K
H
S
K
S
P
L
I
H
N
A
C
F
L
T
F
Q
K
E
LR
F
L
G
H
Y
H
P
I
L
L
P
L
E
S
H
I
K
S
--
E
F
L
H
L
G
L
S
G
A
N
V
T
L
P
F
K
E
R
A
F
Q
V
C
D
K
I
K
G
I
A
L
E
C
G
A
V
N
T
L
V
L
-
E
N
D
E
L
V
G
Y
N
T
D
A
L
G
F
Y
L
S
L
--
K
--
Q
K
--
N
--
Y
--
Q
N
A
L
I
L
G
A
G
G
S
A
K
A
L
A
C
E
L
K
K
Q
G
L
-
Q
V
S
V
L
N
R
S
-------------
S
R
G
-
L
D
F
F
Q
R
---
L
G
C
D
--
C
F
M
E
------
P
P
K
S
A
F
D
L
I
I
N
A
T
S
A
S
L
---
H
--
N
E
L
--
P
L
N
-
K
-
E
V
L
K
G
Y
F
K
E
G
K
L
A
Y
D
L
A
-
A
G
F
L
T
P
F
L
S
L
A
K
E
L
K
T
P
-
F
-
Q
D
G
K
D
M
L
I
Y
Q
A
A
L
S
F
E
K
F
S
A
S
Q
I
P
Y
S
K
A
F
E
-------
65
PsiBlast_CBE
66.87
31%
-1
- C5 -
-
4FR5
1
AROE_HELPY
A:
[1-257]
M
K
L
K
S
F
----
G
V
F
G
N
P
I
K
H
S
K
S
P
L
I
H
N
A
C
F
L
T
F
Q
K
E
LR
F
L
G
H
Y
H
P
I
L
L
P
L
E
S
H
I
K
S
--
E
F
L
H
L
G
L
S
G
A
N
V
T
L
P
F
K
E
R
A
F
Q
V
C
D
K
I
K
G
I
A
L
E
C
G
A
V
N
T
L
V
L
-
E
N
D
E
L
V
G
Y
N
T
D
A
L
G
F
Y
L
S
L
--
K
--
Q
K
--
N
--
Y
--
Q
N
A
L
I
L
G
A
G
G
S
A
K
A
L
A
C
E
L
K
K
Q
G
L
-
Q
V
S
V
L
N
R
S
-------------
S
R
G
-
L
D
F
F
Q
R
---
L
G
C
D
--
C
F
M
E
------
P
P
K
S
A
F
D
L
I
I
N
A
T
S
A
S
L
---
H
--
N
E
L
--
P
L
N
-
K
-
E
V
L
K
G
Y
F
K
E
G
K
L
A
Y
D
L
A
-
S
G
F
L
T
P
F
L
S
L
A
K
E
L
K
T
P
-
F
-
Q
D
G
K
D
M
L
I
Y
Q
A
A
L
S
F
E
K
F
S
A
S
Q
I
P
Y
S
K
A
F
E
-------
59
PsiBlast_CBE
64.81
31%
-4
- C5 -
-
3PHJ
1
AROE_HELPY
A:
[1-257]
M
K
L
K
S
F
----
G
V
F
G
N
P
I
K
H
S
K
S
P
L
I
H
N
A
C
F
L
T
F
Q
K
E
LR
F
L
G
H
Y
H
P
I
L
L
P
L
E
S
H
I
K
S
--
E
F
L
H
L
G
L
S
G
A
N
V
T
L
P
F
K
E
R
A
F
Q
V
C
D
K
I
K
G
I
A
L
E
C
G
A
V
N
T
L
V
L
-
E
N
D
E
L
V
G
Y
N
T
D
A
L
G
F
Y
L
S
L
--
K
---------
Y
--
Q
N
A
L
I
L
G
A
G
G
S
A
K
A
L
A
C
E
L
K
K
Q
G
L
-
Q
V
S
V
L
N
R
S
-------------
S
R
G
-
L
D
F
F
Q
R
---
L
G
C
D
--
C
F
M
E
------
P
P
K
S
A
F
D
L
I
I
N
A
T
S
----------
E
L
--
P
L
N
-
K
-
E
V
L
K
G
Y
F
K
E
G
K
L
A
Y
D
L
A
Y
G
-
F
L
T
P
F
L
S
L
A
K
E
L
K
T
P
-
F
-
Q
D
G
K
D
M
L
I
Y
Q
A
A
L
S
F
E
K
F
S
A
S
Q
I
P
Y
S
K
A
F
E
-------
58
PsiBlast_CBE
64.71
31%
-3
- C5 -
-
3PHJ
1
AROE_HELPY
B:
[1-257]
M
K
L
K
S
F
----
G
V
F
G
N
P
I
K
H
S
K
S
P
L
I
H
N
A
C
F
L
T
F
Q
K
E
LRFL
G
H
Y
H
P
I
L
L
P
L
E
S
H
I
K
S
--
E
F
L
H
L
G
L
S
G
A
N
V
T
L
P
F
K
E
R
A
F
Q
V
C
D
K
I
K
G
I
A
L
E
C
G
A
V
N
T
L
V
L
-
E
N
D
E
L
V
G
Y
N
T
D
A
L
G
F
Y
L
S
L
--
K
---------
Y
--
Q
N
A
L
I
L
G
A
G
G
S
A
K
A
L
A
C
E
L
K
K
Q
G
L
-
Q
V
S
V
L
N
R
S
-------------
S
R
G
-
L
D
F
F
Q
R
---
L
G
C
D
--
C
F
M
E
------
P
P
K
S
A
F
D
L
I
I
N
A
T
S
----------
E
L
--
P
L
N
-
K
-
E
V
L
KGY
F
K
E
G
K
L
A
Y
D
L
A
Y
G
-
F
L
T
P
F
L
S
L
A
K
E
L
K
T
P
-
F
-
Q
D
G
K
D
M
L
I
Y
Q
A
A
L
S
F
E
K
F
S
A
S
Q
I
P
Y
S
K
A
F
E
-------
50
PsiBlast_CBE
64.59
32%
-49
- C5 -
-
3SEF
1
AROE_VIBCH
C:
[33-294]
----------
A
V
F
G
N
P
I
N
H
S
K
S
P
F
I
H
T
L
F
A
R
Q
T
Q
Q
S
----
M
I
Y
T
A
Q
C
V
P
V
D
G
F
T
E
A
A
K
H
F
F
A
Q
G
G
R
G
C
N
V
T
V
P
F
K
E
E
A
Y
R
F
A
D
R
L
T
E
R
A
R
L
A
G
A
V
N
T
L
K
K
-
D
D
G
E
I
L
G
D
N
T
D
G
E
G
L
V
Q
D
L
L
A
Q
--
Q
V
--
L
--
L
K
G
A
T
I
L
L
I
G
A
G
G
A
A
R
G
V
L
K
P
L
L
D
Q
Q
P
A
S
I
T
V
T
N
R
T
----
F
A
---
K
A
-
E
Q
---
L
A
E
L
V
A
A
Y
G
-
E
V
K
-
A
Q
A
F
E
Q
L
K
Q
------
S
Y
D
V
I
I
N
S
T
S
A
---------------
I
-
D
-
P
V
I
---
F
S
S
R
S
V
C
Y
D
M
M
Y
G
-------------------
I
D
G
L
G
M
L
V
G
Q
A
A
E
S
F
M
L
W
R
G
L
R
P
G
T
K
Q
I
L
R
E
L
-----