@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu00040: (2016-06-01 )
MYIQNLELTSYRNYDHAELQFENKVNVIIGENAQGKTNLMEAIYVLSMAKSHRTSNDKELIRWDKDYAKIEGRVMKQNGAIPMQLVISKKGKKGKVNHIEQQKLSQYVGALNTIMFAPEDLNLVKGSPQVRRRFLDMEIGQVSPVYLHDLSLYQKILSQRNHFLKQLQTRKQTDRTMLDVLTDQLVEVAAKVVVKRLQFTAQLEKWAQPIHAGISRGLEELTLKYHTALDVSDPLDLSKIGDSYQEAFSKLREKEIERGVTLSGPHRDDVLFYVNGRDVQTYGSQGQQRTTALSLKLAEIDLIHEEIGEYPILLLDDVLSELDDYRQSHLLHTIQGRVQTFVTTTSVDGIDHETLRQAGMFRVQNGALVK
Atome Classification :
(20 SA)
----.........10...-..--..--.20........30........40..-..--------..--..50.......----------------..60------........70........80..---......90---..-----..-...----..100------........-------.110.---......120..---------.....130.......140.......150.......160.......170.......180...-....190.......200.......210--------..-----....----------.220------.......230...--....240....---...250.......260.......270.....-----------..280........290....--...300----.......----..310----------------------------------.........320.......330.....-.--.--340.......350....-...--360.......370------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----
M
Y
I
QNLELTSYRNY-DH--
A
E
--
L
Q
FEN
K
V
N
V
I
IGENAQG
K
T
N
L
M
E
A
I
-
Y
V
--------
L
S
--
M
A
K
-SHRTS
N
D
----------------
K
E
L
I
------
R
WD
K
D
Y
A
K
IE
G
R
V
M
KQNGA
I
P
M
---
Q
L
V
I
SKK----GK-----KG-KV
N
----
H
I
E
--------
Q
Q
K
L
S
Q
Y
V
-------
G
A
L
N
T
---
I
M
FAPEDLNLV---------KG
S
P
Q
V
R
R
R
F
L
DMEIGQVS
P
V
Y
L
H
D
L
S
L
Y
Q
K
I
L
S
Q
R
N
H
F
L
K
Q
L
Q
T
RKQT
D
R
T
M
L
D
V
L
T
D
Q
L
-
V
E
V
A
A
K
V
V
V
K
R
L
Q
F
T
A
Q
L
E
K
W
A
Q
P
I
H
A
--------
G
I
-----
S
R
G
L
----------
E
E
L
T
------
L
K
Y
H
T
ALDVSDPL--
D
L
S
K
I
G
D
S
Y
Q
E
---
A
F
S
K
L
R
E
K
E
I
ERGVTLSGPHRD
D
V
L
F
Y
VNG
R
-----------
D
V
Q
-
T
YGSQGQ
Q
R
T
T
A
L
S
L
K
--
L
A
E
I
------
D
L
I
H
E
E
I----GEY------------------------------------P
I
L
L
L
D
D
V
L
S
E
L
D
D
Y
R
Q
S
H
L
L
H
T
I
QGR-
V
--
Q
--
T
F
V
T
TTSVDGI
D
H
E
T
L
R
-
Q
AG--
M
F
R
VQNGALVK--------------------------
1
PsiBlast_PDB
92.33
31%
-45
- C2 -
2O5V
1
RECF_DEIRA
A:
[6-345]
------
L
S
A
L
S
T
L
N
Y
R
N
L
-
A
P
--
G
T
--
L
N
F
P
E
G
V
T
G
I
Y
G
E
N
G
A
G
K
T
N
L
L
E
A
A
-
Y
---------
L
A
--
L
T
G
-
Q
T
D
A
P
R
I
----------------
E
Q
L
I
------
Q
A
G
E
T
E
A
Y
V
R
A
D
-
L
Q
Q
G
G
S
L
S
I
---
Q
E
V
G
L
G
R
----
G
R
-----
R
Q
L
K
V
D
----
G
V
R
--------
A
R
T
G
D
L
P
R
-------
G
--
G
A
---
V
W
I
R
P
E
D
S
E
L
V
---------
F
G
P
P
S
G
R
R
A
Y
L
D
S
L
L
S
R
L
S
A
R
Y
G
E
Q
L
S
R
Y
E
R
T
V
S
Q
R
N
A
A
L
R
G
------
G
E
E
W
A
M
H
V
W
D
D
V
L
-
L
K
L
G
T
E
I
M
L
F
R
R
R
A
L
T
R
L
D
E
L
A
R
E
A
N
A
--------
Q
L
G----
S
R
K
T
----------
L
A
L
T
------
L
T
E
S
T
S
P
E
--------------
T
Y
A
A
---
D
L
R
G
R
R
A
E
E
L
A
R
G
S
T
V
T
G
P
H
R
D
D
L
L
L
T
L
G
D
F
-----------
P
A
S
-
D
Y
A
S
R
G
E
G
R
T
V
A
L
A
L
R
--
R
A
E
L
------
E
L
L
R
E
K
F
----
G
E
D
------------------------------------
P
V
L
L
L
D
D
F
T
A
E
L
D
P
H
R
R
Q
Y
L
L
D
L
A
A
S
V
-
P
--
Q
--
A
I
V
T
G
T
E
L
A
P
G
A
A
L
T
L
R
A
Q
A
G
--
R
F
-----------------------------------
37
HHSearch
88.27
30%
-64
- C2 -
2O5V
1
RECF_DEIRA
A:
[4-345]
----
V
R
L
S
A
L
S
T
L
N
Y
R
N
L
-
A
P
--
G
T
--
L
N
F
P
E
G
V
T
G
I
Y
G
E
N
G
A
G
K
T
N
L
L
E
A
A
-
Y
L
--------
A
L
--
T
G
Q
-
T
D
A
P
-
R
I
----------------
E
Q
L
I
------
Q
A
G
E
T
E
A
Y
V
R
A
D
L
Q
Q
G
G
S
L
S
I
Q
---
E
V
G
L
G
R
G
----
R
R
-----
Q
L
-
K
V
D
----
G
V
R
--------
A
-
R
T
G
D
L
P
--------
R
G
G
A
---
V
W
I
R
P
E
D
S
E
L
V
---------
F
G
P
P
S
G
R
R
A
Y
L
D
S
L
L
S
R
L
S
A
R
Y
G
E
Q
L
S
R
Y
E
R
T
V
S
Q
R
N
A
A
L
R
G
G
E
------
E
W
A
M
H
V
W
D
D
V
L
-
L
K
L
G
T
E
I
M
L
F
R
R
R
A
L
T
R
L
D
E
L
A
R
E
A
N
A
--------
Q
L
-----
G
S
R
-----------
K
T
L
A
------
L
T
L
T
E
S
T
S
P
------------
E
T
Y
A
A
---
D
L
R
G
R
R
A
E
E
L
A
R
G
S
T
V
T
G
P
H
R
D
D
L
L
L
T
L
G
D
F
-----------
P
A
S
-
D
Y
A
S
R
G
E
G
R
T
V
A
L
A
L
R
--
R
A
E
L
------
E
L
L
R
E
K
F
----
G
E
D
------------------------------------
P
V
L
L
L
D
D
F
T
A
E
L
D
P
H
R
R
Q
Y
L
L
D
L
A
A
-
S
V
P
--
Q
--
A
I
V
T
G
T
E
L
A
P
G
A
-------
A
L
--
T
L
R
A
Q
A
G
R
F
----------------------------
27
Fugue
87.20
28%
-58
- C2 -
2O5V
1
RECF_DEIRA
A:
[2-359]
--GD
V
R
L
S
A
L
S
T
L
N
Y
R
N
L
-
A
P
--
G
T
--
L
N
F
P
E
G
V
T
G
I
Y
G
E
N
G
A
G
K
T
N
L
L
E
A
A
-
Y
L
--------
A
L
--
T
G
Q
-
T
D
A
-
P
R
I
----------------
E
Q
L
I
------
Q
A
G
E
T
E
A
Y
V
R
A
D
L
Q
Q
G
G
S
L
S
I
Q
---
E
V
G
L
G
R
G
----
R
R
-----
Q
L
-
K
V
D
----
G
V
R
--------
A
R
--
T
G
D
L
-------
P
R
G
G
A
---
V
W
I
R
P
E
D
S
E
L
V
---------
F
G
P
P
S
G
R
R
A
Y
L
D
S
L
L
S
R
L
S
A
R
Y
G
E
Q
L
S
R
Y
E
R
T
V
S
Q
R
N
A
A
L
R
G
G
------
E
E
W
A
M
H
V
W
D
D
V
L
-
L
K
L
G
T
E
I
M
L
F
R
R
R
A
L
T
R
L
D
E
L
A
R
E
A
N
A
--------
Q
L
-----
G
-
S
R
----------
K
T
L
A
------
L
T
L
T
E
S
T
S
------------
P
E
T
Y
A
A
---
D
L
R
G
R
R
A
E
E
L
A
R
G
S
T
V
T
G
P
H
R
D
D
L
L
L
T
L
G
D
F
-----------
P
A
S
-
D
Y
A
S
R
G
E
G
R
T
V
A
L
A
L
R
--
R
A
E
L
------
E
L
L
R
E
K
F
----
G
E
D
------------------------------------
P
V
L
L
L
D
D
F
T
A
E
L
D
P
H
R
R
Q
Y
L
L
D
L
A
A
S
V
-
P
--
Q
--
A
I
V
T
G
T
E
L
A
P
G
A
A
L
T
L
R
-
A
Q
A
G
R
F
T
P
V
A
D
E
E
M
Q
A
EGTA----------------------
2
PsiBlast_PDB
67.21
21%
-32
- C2 -
3QKT
3
RAD50_PYRFU
A:
[1-298]
----
M
K
L
E
R
V
T
V
K
N
F
R
S
H
-
S
D
--
T
V
--
V
E
F
K
E
G
I
N
L
I
I
G
Q
N
G
S
G
K
S
S
L
L
D
A
I
-
L
V
---------
G
--
L
Y
W
-
P
L
R
I
K
D
I
----------------
K
K
-----------
D
E
F
T
K
V
G
A
R
------
D
T
Y
I
---
D
L
I
F
E
K
D
----
G
T
-----
K
Y
-
R
I
T
---------------
R
R
F
L
K
G
Y
S
-------
S
----------------------------
G
E
I
H
A
M
K
R
L
V
G
N
E
W
K
H
V
T
E
P
S
S
K
A
I
S
A
F
M
E
K
L
I
P
Y
N
I
F
L
N
A
I
Y
I
R
Q
G
Q
I
D
A
I
L
E
--
S
D
E
A
-
R
E
K
V
V
R
E
V
L
N
L
D
K
F
E
T
A
Y
K
K
L
S
E
--
L
K
--------
G
G
-----
S
G
G
T
----------
E
E
L
I
------
E
K
V
K
K
Y
K
A
L
A
R
E
A
--
A
L
S
K
I
G
E
L
A
S
E
---
I
F
A
E
F
T
E
G
K
Y
S
E
V
V
V
R
A
E
E
N
K
V
R
L
F
V
V
W
E
G
K
-----------
E
R
P
L
T
F
L
S
G
G
E
R
I
A
L
G
L
A
F
R
--
L
A
M
S
------
L
Y
L
A
-------
G
E
I
------------------------------------
S
L
L
I
L
D
E
P
T
P
Y
L
D
E
E
R
R
R
K
L
I
T
I
M
E
---------------------------------------------------------------------
9
PsiBlast_PDB
65.80
20%
-34
- C2 -
3QKU
2
?
A:
[1-318]
----
M
K
L
E
R
V
T
V
K
N
F
R
S
H
-
S
D
--
T
V
--
V
E
F
K
E
G
I
N
L
I
I
G
Q
N
G
S
G
K
S
S
L
L
D
A
I
-
L
V
---------
G
--
L
Y
W
-
P
L
R
I
K
D
I
----------------
K
K
-----------
D
E
F
T
K
V
G
A
R
------
D
T
Y
I
---
D
L
I
F
E
K
D
----
G
T
-----
K
Y
-
R
I
T
---------------
R
R
F
L
K
G
Y
S
-------
S
----------------------------
G
E
I
H
A
M
K
R
L
V
G
N
E
W
K
H
V
T
E
P
S
S
K
A
I
S
A
F
M
E
K
L
I
P
Y
N
I
F
L
N
A
I
Y
I
R
Q
G
Q
I
D
A
I
L
E
--
S
D
E
A
-
R
E
K
V
V
R
E
V
L
N
L
D
K
F
E
T
A
Y
K
K
L
S
E
L
K
K
T
I
N
N
R
I
K
EY
G
G
-----
S
G
G
I
K
D
L
E
K
A
K
D
F
T
E
E
L
I
------
E
K
V
K
K
Y
K
A
L
A
R
E
A
--
A
L
S
K
I
G
E
L
A
S
E
---
I
F
A
E
F
T
E
G
K
Y
S
E
V
V
V
R
A
E
E
N
K
V
R
L
F
V
V
W
E
G
K
-----------
E
R
P
L
T
F
L
S
G
G
E
R
I
A
L
G
L
A
F
R
--
L
A
M
S
------
L
Y
L
A
-------
G
E
I
------------------------------------
S
L
L
I
L
D
E
P
T
P
Y
L
D
E
E
R
R
R
K
L
I
T
I
M
E
---------------------------------------------------------------------
5
PsiBlast_PDB
63.53
21%
-28
- C2 -
4NCK
-
?
A:
[1-298]
----
M
K
L
E
R
V
T
V
K
N
F
R
S
H
-
S
D
--
T
V
--
V
E
F
K
E
G
I
N
L
I
I
G
Q
N
G
S
G
K
S
S
L
L
D
A
I
-
L
V
---------
G
--
L
Y
W
-
P
L
R
I
K
D
I
----------------
K
K
-----------
D
E
F
T
K
V
G
A
R
------
D
T
Y
I
---
D
L
I
F
E
K
D
----
G
T
-----
K
Y
-
R
I
T
---------------
R
R
F
L
K
G
Y
S
-------
S
----------------------------
G
E
I
H
A
M
K
R
L
V
G
N
E
W
K
H
V
T
E
P
S
S
K
A
I
S
A
F
M
E
K
L
I
P
Y
N
I
F
L
N
A
I
Y
I
R
Q
G
Q
I
D
A
I
L
E
--
S
D
E
A
-
R
E
K
V
V
R
E
V
L
N
---------------------------------------------------------
K
V
K
K
Y
K
A
L
A
R
E
A
--
A
L
S
K
I
G
E
L
A
S
E
---
I
F
A
E
F
T
E
G
K
Y
S
E
V
V
V
R
A
E
E
N
K
V
R
L
F
V
V
W
E
G
K
-----------
E
R
P
L
T
F
L
S
G
G
E
G
I
A
L
G
L
A
F
R
--
L
A
M
S
------
L
Y
L
A
-------
G
E
I
------------------------------------
S
L
L
I
L
D
E
P
T
P
Y
L
D
E
E
R
R
R
K
L
I
T
I
M
E
---------------------------------------------------------------------
4
PsiBlast_PDB
63.30
21%
-30
- C2 -
4NCJ
6
RAD50_PYRFU
A:
[1-298]
----
M
K
L
E
R
V
T
V
K
N
F
R
S
H
-
S
D
--
T
V
--
V
E
F
K
E
G
I
N
L
I
I
G
Q
N
G
S
G
K
S
S
L
L
D
A
I
-
L
V
---------
G
--
L
Y
W
-
P
L
R
I
K
D
I
----------------
K
K
-----------
D
E
F
T
K
V
G
A
R
------
D
T
Y
I
---
D
L
I
F
E
K
D
----
G
T
-----
K
Y
-
R
I
T
---------------
R
R
F
L
K
G
Y
S
-------
S
----------------------------
G
E
I
H
A
M
K
R
L
V
G
N
E
W
K
H
V
T
E
P
S
S
K
A
I
S
A
F
M
E
K
L
I
P
Y
N
I
F
L
N
A
I
Y
I
R
Q
G
Q
I
D
A
I
L
E
--
S
D
E
A
-
R
E
K
V
V
R
E
V
L
N
L
-----------------------------------------------------------
K
Y
K
A
L
A
R
E
A
--
A
L
S
K
I
G
E
L
A
S
E
---
I
F
A
E
F
T
E
G
K
Y
S
E
V
V
V
R
A
E
E
N
K
V
R
L
F
V
V
W
E
G
K
-----------
E
R
P
L
T
F
L
S
G
G
E
R
I
A
L
G
L
A
F
E
--
L
A
M
S
------
L
Y
L
A
-------
G
E
I
------------------------------------
S
L
L
I
L
D
E
P
T
P
Y
L
D
E
E
R
R
R
K
L
I
T
I
M
E
---------------------------------------------------------------------
30
Fugue
58.56
17%
-47
- C2 -
1E69
-
?
A:
[1-1164]
----
M
R
L
K
K
L
Y
L
K
G
F
K
S
F
G
R
P
--
S
L
--
I
G
F
S
D
R
V
T
A
I
V
G
P
N
G
S
G
K
S
N
I
I
D
A
I
-
K
W
--------
V
---
F
G
E
-
K
F
D
M
I
F
A
----------------
G
S
E
N
------
L
P
P
A
G
S
A
Y
V
E
L
V
F
E
E
N
G
E
E
I
T
V
---
A
R
E
L
K
R
T
----
G
E
-----
N
T
-
Y
Y
L
----
N
G
S
--------
P
V
R
L
K
D
I
R
-------
D
R
F
A
G
---
T
G
L
G
V
D
F
Y
S
I
V
---------
G
-----------------------------------
Q
G
Q
I
D
R
I
V
N
A
Y
Q
R
V
N
E
S
F
N
R
F
I
S
L
L
-
F
F
G
G
----------
E
G
R
L
E
I
S
I
R
K
---------------------------------------------------------------------------------------
P
G
R
R
D
Q
K
L
S
L
L
----------------------
S
G
G
E
K
A
L
V
G
L
A
L
L
--
F
A
L
M
-----------
E
I
----
K
P
S
------------------------------------
P
F
Y
V
L
D
E
V
D
S
P
L
D
D
Y
N
A
E
R
F
K
R
L
L
K
E
N
-
S
K
H
T
--
Q
F
I
V
I
T
H
N
K
I
V
M
E
A
A
D
L
-
L
H
G
--
V
T
M
V
N
G
V
S
A
I
V
PVEV----------------------
3
PsiBlast_PDB
58.34
21%
-25
- C2 -
4NCI
-
?
A:
[1-841]
----
M
K
L
E
R
V
T
V
K
N
F
R
S
H
-
S
D
--
T
V
--
V
E
F
K
E
G
I
N
L
I
I
G
Q
N
G
S
G
K
S
S
L
L
D
A
I
-
L
V
---------
G
--
L
Y
W
-
P
L
R
I
K
D
I
----------------
K
K
-----------
D
-------
R
------
D
T
Y
I
---
D
L
I
F
E
K
D
----
G
T
-----
K
Y
-
R
I
T
---------------
R
R
F
L
K
G
Y
S
-------
S
----------------------------
G
E
I
H
A
M
K
R
L
V
G
N
E
W
K
H
V
T
E
P
S
S
K
A
I
S
A
F
M
E
K
L
I
P
Y
N
I
F
L
N
A
I
Y
I
R
Q
G
Q
I
D
A
I
L
E
--
S
D
E
A
-
R
E
K
V
V
R
E
V
L
N
L
D
K
----------------------------------------------
I
------
E
K
V
K
K
Y
K
A
L
A
R
E
A
--
A
L
S
K
I
G
E
L
A
S
E
---
I
F
A
E
F
T
E
G
K
Y
S
E
V
V
V
R
A
E
E
N
K
V
R
L
F
V
V
W
E
G
K
-----------
E
R
P
L
T
F
L
S
G
G
E
R
I
A
L
G
L
A
F
E
--
L
A
M
S
------
L
Y
L
A
-------
G
E
I
------------------------------------
S
L
L
I
L
D
E
P
T
P
Y
L
D
E
E
R
R
R
K
L
I
T
I
M
E
---------------------------------------------------------------------
28
Fugue
53.17
13%
-20
- C2 -
3EUJ
2
MUKB_HAEDU
A:
[3-483]
M
I
A
R
G
K
F
R
S
L
T
L
I
N
W
N
G
F
-
F
A
--
R
T
--
F
D
F
D
E
L
V
T
T
L
S
G
G
N
G
A
G
K
S
T
T
M
A
G
F
-
V
T
--------
A
L
--
I
P
D
-
L
T
L
L
N
F
R
NTTEAGSTSSSRDKGL
Y
G
K
L
------
K
A
G
V
C
Y
A
V
L
E
T
V
N
S
R
A
Q
R
I
I
T
G
---
V
R
L
Q
Q
I
A
----
G
R
-----
D
K
-
K
V
D
I
R
P
F
S
L
Q
NVPMTDS
V
I
S
L
F
T
E
Q
V
-------
A
N
K
A
R
---
V
L
S
L
N
D
L
K
E
K
F
E
ETA
V
T
F
--
K
P
Y
H
S
I
T
D
Y
H
S
F
M
F
D
L
G
I
L
P
K
R
L
R
S
S
S
D
R
N
K
F
Y
K
L
I
E
A
S
L
Y
G
G
I
S
S
V
I
T
K
--
S
L
R
D
Y
L
L
P
E
-
N
S
G
V
R
Q
A
F
Q
D
A
E
S
V
A
N
I
L
R
K
T
I
Q
R
E
Q
N
--------
R
I
-----
L
Q
L
N
----------
Q
G
L
Q
NIAFGQ
V
K
G
V
R
L
V
V
N
I
R
D
T
--
H
S
I
L
L
N
A
L
S
D
Q
---
S
F
S
E
A
L
A
M
L
Y
K
R
I
G
E
E
L
L
D
Y
R
N
Y
L
D
L
E
V
E
T
L
R
GAYGWMRAES
S
A
L
-
S
T
G
E
A
I
G
T
G
M
S
I
L
L
M
V
--
V
Q
S
W
------
E
E
E
S
R
R
M
RAKD
I
L
P
------------------------------------
C
R
L
L
F
L
D
Q
A
A
R
L
D
A
M
S
I
N
T
L
F
E
L
C
E
R
L
D
M
--
Q
--
L
L
I
A
A
P
--
E
N
I
S
P
E
R
G
T
-
T
Y
K
--
L
V
R
K
I
L
A
N
Q
E
Y
V
H
V
V
G
L
K
GFG----------------
31
Fugue
50.90
15%
-31
- C2 -
4UX3
2
SMC3_YEAST
A:
[3-527]
-----
Y
I
K
R
V
I
I
K
G
F
K
T
Y
-
R
N
ET
I
I
--
D
N
F
S
P
H
Q
N
V
I
I
G
S
N
G
S
G
K
S
N
F
F
A
A
I
R
F
V
--------
L
S
--
D
D
Y
-
S
N
L
K
R
E
E
----------------
R
Q
G
L
------
I
H
Q
G
S
----
G
G
S
V
M
S
A
S
V
E
I
V
I
---
R
R
T
V
G
L
K
----
K
D
DYQLN
D
R
-
N
V
T
----
K
G
D
--------
I
V
R
M
L
E
T
A
-------
G
F
S
M
N
NPY
N
I
V
P
Q
G
K
I
V
A
L
---------
T
N
A
K
D
K
E
R
L
Q
L
L
E
D
V
V
G
-
A
K
S
F
E
V
K
L
K
A
S
L
K
K
M
E
E
T
E
Q
K
K
I
Q
I
N
K
E
M
G
E
L
N
S
K
L
S
E
M
E
Q
E
R
-
K
E
L
E
K
Y
N
E
L
E
R
N
R
K
I
Y
Q
F
T
L
Y
D
R
E
L
N
E
--------
V
I
N
QMET
S
D
Q
L
----------
L
Q
R
L
------
N
D
M
N
T
E
I
S
G
L
K
N
V
--
N
K
R
A
F
E
N
F
K
K
F
---
N
E
R
R
K
D
L
A
E
R
A
S
E
L
D
E
S
K
D
S
I
Q
D
L
I
V
K
L
K
Q
Q
-----------
K
V
N
-
A
V
D
S
T
F
Q
K
V
S
E
N
F
E
A
V
--
F
E
R
L
V
PR
G
T
A
K
L
I
I
H
S
I
----
S
V
S
F
N
SKQNEQLHVEQLS
G
G
Q
K
T
V
C
A
I
A
L
I
L
A
I
Q
M
V
D
PA
S
F
Y
L
F
D
E
I
D
A
A
L
D
K
Q
Y
R
T
A
V
A
T
L
L
K
E
L
-
S
--
K
N
A
Q
F
I
C
T
T
F
R
T
D
M
L
Q
V
A
D
K
-
F
F
R
--
V
K
Y
E
N
K
I
S
T
V
I
E
V
N
R
E
E
A
I
G
F
I
R--------------
36
Fugue
50.39
17%
-9
- C1 -
4PG7
9
?
A:
[20-446]
---H
M
K
K
L
N
I
A
L
L
G
L
G
T
V
-
G
S
--
G
V
--
V
K
I
I
E
E
N
R
Q
Q
I
Q
D
T
L
-
N
K
D
I
V
I
K
H
I
-
L
V
RDKSKKRP
L
N
--
I
S
Q
-
Y
H
L
T
E
D
V
----------------
N
E
I
L
------
N
D
D
S
L
D
I
I
V
E
V
M
G
G
I
E
P
T
V
D
W
L
---
R
T
A
L
K
N
K
----
K
---------
H
V
I
----
T
A
N
--------
K
D
L
L
A
V
H
L
-------
K
L
L
E
D
---
L
A
E
E
N
G
V
A
L
K
F
---------
E
A
S
V
A
G
G
P
N
N
I
S
K
F
M
G
I
L
N
G
T
S
N
F
I
L
S
K
M
T
K
E
Q
T
T
F
E
E
A
L
D
E
A
K
R
L
G
F
A
E
A
D
P
T
D
D
V
E
G
---
V
D
A
A
R
K
V
V
I
T
S
Y
L
S
F
N
Q
V
I
K
L
N
D
V
K
R
-----------------
R
G
I
----------
S
G
V
T
---------
L
T
D
I
N
V
A
D
Q
L
G
Y
K
I
K
L
I
G
K
G
I
Y
E
NG
K
V
N
A
S
V
E
P
T
L
I
D
K
K
H
Q
L
A
A
V
E
D
E
Y
N
A
I
Y
V
I
G
D
AV
G
--------
D
T
M
-
F
Y
G
K
G
A
G
S
L
A
T
G
S
A
V
V
S
D
L
L
N
V
------
A
L
F
F
E
S
T
----
L
P
P
------------------------------------
H
F
E
L
K
T
D
K
T
R
E
M
E
K
S
N
F
F
V
V
V
N
H
V
K
G
S
-
I
--
E
--
N
F
E
N
E
L
K
A
I
L
P
F
H
R
S
L
R
-
V
A
N
--
Y
D
N
Q
S
Y
A
A
V
I
V
GLESSP
E
E
L
I
T
K
H
GYEVD
K
V
Y
P
V
E
GV
6
PsiBlast_PDB
48.65
25%
-23
- C2 -
1XEW
-
SMC_PYRFU
X:
[3-164]
-----
Y
I
E
K
L
E
L
K
G
F
K
S
Y
-
G
N
--
K
K
VV
I
P
F
S
K
G
F
T
A
I
V
G
A
N
G
S
G
K
S
N
I
G
D
A
I
L
F
V
--------
L
G
GL
S
A
K
-------------------------------------
A
K
Y
A
E
V
A
I
Y
F
N
N
E
D
R
G
F
P
I
DED
E
V
V
I
R
R
R
VYPD
G
R
-----
S
S
-
Y
W
L
----
N
G
R
--------
R
A
T
R
S
E
I
L
-------
D
I
L
T
A
---
A
M
I
S
P
D
G
Y
N
I
V
LQGDITKFI
K
M
S
P
L
E
R
R
L
L
I
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
46.28
25%
-28
- C2 -
1XEX
2
?
A:
[3-164]
-----
Y
I
E
K
L
E
L
K
G
F
K
S
Y
-
G
N
--
K
K
V
V
I
P
F
S
K
G
F
T
A
I
V
G
A
N
G
S
G
K
S
N
I
G
D
A
I
L
F
V
--------
L
G
GL
S
A
K
-
A
M
R
A
S
R
I
----------------
S
D
L
I
FAGSKN
E
P
P
A
K
Y
A
E
V
A
I
Y
F
N
N
E
D
R
G
F
P
I
DED
E
V
V
I
R
R
R
V
Y
PD
G
R
-----
S
S
-
Y
W
L
----
N
G
R
--------
R
A
T
R
S
E
I
L
-------
D
I
L
T
A
---
A
M
I
S
P
D
G
Y
N
I
V
LQG
D
I
T
K
F
I
K
M
S
P
L
E
R
R
L
L
I
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
Fugue
45.84
15%
-33
- C2 -
4XGC
-
A:
[38-388]
-------------------
P
C
--
R
E
--
R
E
F
E
N
I
Y
A
F
L
E
G
K
I
Q
D
Q
------
C
M
-
Y
V
--------
S
G
--
V
P
G
-
T
G
K
T
A
T
V
----------------
T
G
V
I
------
R
T
L
Q
E
Y
L
E
I
N
G
M
R
L
T
-----
E
P
---
R
Q
A
Y
V
Q
I
----
Y
K
-----
Q
L
-
T
G
K
----
T
V
S
--------
W
E
Q
A
H
A
L
L
-------
E
K
R
T
T
---
V
L
L
V
D
E
L
D
I
L
C
---------
N
R
R
Q
D
V
V
Y
N
L
L
D
W
P
T
K
L
V
V
V
T
I
A
N
T
M
D
L
P
E
R
L
G
L
T
R
L
T
F
------
Q
P
Y
S
H
K
Q
L
Q
E
I
V
T
A
R
L
G
K
G
E
A
V
Q
L
V
A
R
K
V
A
A
V
S
G
D
A
R
R
A
L
D
I
C
R
--------
R
A
-----
T
E
I
A
----------
D
T
A
A
------
V
K
C
V
T
M
L
H
V
Q
Q
A
L
--
A
E
M
I
----
A
S
A
---
K
V
Q
A
I
R
N
----------
C
S
R
M
E
Q
I
F
L
Q
A
I
A
A
-----------
E
V
T
-
R
T
G
V
E
---
E
T
T
F
M
G
V
---
Y
Q
Q
V
------
E
T
I
A
A
F
M
----
G
V
-----------------------------------------------
T
F
P
P
P
G
R
A
L
R
L
C
S
K
L
G
A
-
E
--
R
--
L
I
I
S
E
H
S
R
N
D
L
F
Q
K
I
L
L
-
N
V
S
--
A
D
D
I
H
Y
A
L
R
V
---------------------------
11
PsiBlast_PDB
43.37
31%
4
- C2 -
1US8
-
RAD50_PYRFU
A:
[1-63]
----
M
K
L
E
R
V
T
V
K
N
F
R
S
H
-
S
D
--
T
V
--
V
E
F
K
E
G
I
N
L
I
I
G
Q
N
G
S
G
K
S
S
L
L
D
A
I
-
L
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
Fugue
42.32
17%
-39
- C2 -
1F2U
2
?
A:
[1-149]
----
M
K
L
E
R
V
T
V
K
N
F
R
S
H
-
S
D
--
T
V
--
V
E
F
K
E
G
I
N
L
I
I
G
Q
N
G
S
G
K
S
S
L
L
D
A
I
-
L
V
--------
G
L
--
Y
W
P
L
R
I
K
D
I
K
K
----------------
D
E
F
T
------
K
V
G
A
R
D
T
Y
I
D
L
I
F
E
K
D
G
T
K
Y
R
I
---
T
R
R
F
L
K
G
----
Y
S
-----
S
G
-
E
I
H
----
A
M
K
--------
R
L
V
G
N
E
W
K
HVTEPS
S
K
A
I
S
A
---
F
M
E
K
L
I
P
Y
N
I
F
---------
L
N
A
I
Y
I
R
Q
G
Q
I
D
A
I
L
E
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
41.96
31%
3
- C2 -
3QKR
1
?
A:
[1-45]
----
M
K
L
E
R
V
T
V
K
N
F
R
S
H
-
S
D
--
T
V
--
V
E
F
K
E
G
I
N
L
I
I
G
Q
N
G
S
G
K
S
S
L
L
D
A
I
-
L
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
41.49
27%
13
- C2 -
3AUX
2
RAD50_METJA
A:
[3-69]
----
M
I
L
K
E
I
R
M
N
N
F
K
S
H
-
V
N
--
S
R
--
I
K
F
E
K
G
I
V
A
I
I
G
E
N
G
S
G
K
S
S
I
F
E
A
V
-
F
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
41.35
31%
7
- C2 -
1F2T
-
RAD50_PYRFU
A:
[1-49]
----
M
K
L
E
R
V
T
V
K
N
F
R
S
H
-
S
D
--
T
V
--
V
E
F
K
E
G
I
N
L
I
I
G
Q
N
G
S
G
K
S
S
L
L
D
A
I
-
L
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------