@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PF00186_DYR_CA: (2014-08-30 )
MSKPNVAIIVAALKPALGIGYKGKMPWRLRKEIRYFKDVTTRTTKPNTRNAVIMGRKTWESIPQKFRPLPDRLNIILSRSYENKIIDDNIIHASSIESSLNLVSDVERVFIIGGAEIYNELINNSLVSHLLITEIEHPSPESIEMDTFLKFPLESWTKQPKSELQKFVGDTVLEDDIKEGDFTYNYTLWTRK
Atome Classification :
(39 SA)
....-.....10........20......-..30........40..------.---.....50........60........70........80....--------------....90....-------....100..---------.------....110.......120.....---..130.......-140.--......150---------------.-..------......160---.......170--...--------------...--.180.......190
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MSKP-
N
V
A
I
I
V
AALKPALGIGYKGKM
P
W
-
R
L
R
K
E
I
R
Y
F
K
D
V
TTRT------T---KPNTR
N
A
V
I
MG
R
K
T
W
E
S
I
P
Q
K
FRPL
P
D
R
L
N
I
I
L
SRSYENKI--------------IDDNII
H
A
S
S
-------
I
E
S
S
L
N
L
V
S
---------D------V
E
R
V
F
I
IG
G
A
E
I
Y
N
E
L
I
N
N
S
L
V
---
S
H
L
L
I
T
EIEHPS-PESI--
E
M
D
T
F
LK-----------------F-
P
L
------
E
S
WTKQ
P
K
S
---
E
L
Q
K
F
VGD
T
V
--
L
E
D
--------------DIK--EG
D
F
T
Y
N
Y
T
L
W
TRK
9
PsiBlast_PDB
97.70
98%
-157
- C3 -
1M7A
2
DYR_CANAX
A:
[1-192]
M
L
K
P
-
N
V
A
I
I
V
A
A
L
K
P
A
L
G
I
G
Y
K
G
K
M
P
W
-
R
L
R
K
E
I
R
Y
F
K
D
V
T
T
R
T
------
T
---
K
P
N
T
R
N
A
V
I
M
G
R
K
T
W
E
S
I
P
Q
K
F
R
P
L
P
D
R
L
N
I
I
L
S
R
S
Y
E
N
E
I
--------------
I
D
D
N
I
I
H
A
S
S
-------
I
E
S
S
L
N
L
V
S
---------
D
------
V
E
R
V
F
I
I
G
G
A
E
I
Y
N
E
L
I
N
N
S
L
V
---
S
H
L
L
I
T
E
I
E
H
P
S
-
P
E
S
I
--
E
M
D
T
F
L
K
-----------------
F
-
P
L
------
E
S
W
T
K
Q
P
K
S
---
E
L
Q
K
F
V
G
D
T
V
--
L
E
D
--------------
D
I
K
--
E
G
D
F
T
Y
N
Y
T
L
W
T
R
K
11
PsiBlast_PDB
97.65
98%
-154
- C3 -
3QLS
5
DYR_CANAX
A:
[1-192]
M
L
K
P
-
N
V
A
I
I
V
A
A
L
K
P
A
L
G
I
G
Y
K
G
K
M
P
W
-
R
L
R
K
E
I
R
Y
F
K
D
V
T
T
R
T
------
T
---
K
P
N
T
R
N
A
V
I
M
G
R
K
T
W
E
S
I
P
Q
K
F
R
P
L
P
D
R
L
N
I
I
L
S
R
S
Y
E
N
E
I
--------------
I
D
D
N
I
I
H
A
S
S
-------
I
E
S
S
L
N
L
V
S
---------
D
------
V
E
R
V
F
I
I
G
G
A
E
I
Y
N
E
L
I
N
N
S
L
V
---
S
H
L
L
I
T
E
I
E
H
P
S
-
P
E
S
I
--
E
M
D
T
F
L
K
-----------------
F
-
P
L
------
E
S
W
T
K
Q
P
K
S
---
E
L
Q
K
F
V
G
D
T
V
--
L
E
D
--------------
D
I
K
--
E
G
D
F
T
Y
N
Y
T
L
W
T
R
K
7
PsiBlast_PDB
97.65
98%
-155
- C3 -
1M78
2
DYR_CANAX
A:
[1-192]
M
L
K
P
-
N
V
A
I
I
V
A
A
L
K
P
A
L
G
I
G
Y
K
G
K
M
P
W
-
R
L
R
K
E
I
R
Y
F
K
D
V
T
T
R
T
------
T
---
K
P
N
T
R
N
A
V
I
M
G
R
K
T
W
E
S
I
P
Q
K
F
R
P
L
P
D
R
L
N
I
I
L
S
R
S
Y
E
N
E
I
--------------
I
D
D
N
I
I
H
A
S
S
-------
I
E
S
S
L
N
L
V
S
---------
D
------
V
E
R
V
F
I
I
G
G
A
E
I
Y
N
E
L
I
N
N
S
L
V
---
S
H
L
L
I
T
E
I
E
H
P
S
-
P
E
S
I
--
E
M
D
T
F
L
K
-----------------
F
-
P
L
------
E
S
W
T
K
Q
P
K
S
---
E
L
Q
K
F
V
G
D
T
V
--
L
E
D
--------------
D
I
K
--
E
G
D
F
T
Y
N
Y
T
L
W
T
R
K
48
HHSearch
97.62
99%
-157
- C3 -
1AOE
2
DYR_CANAX
A:
[1-192]
M
L
K
P
-
N
V
A
I
I
V
A
A
L
K
P
A
L
G
I
G
Y
K
G
K
M
P
W
-
R
L
R
K
E
I
R
Y
F
K
D
V
T
T
R
T
------
T
---
K
P
N
T
R
N
A
V
I
M
G
R
K
T
W
E
S
I
P
Q
K
F
R
P
L
P
D
R
L
N
I
I
L
S
R
S
Y
E
N
E
I
--------------
I
D
D
N
I
I
H
A
S
S
-------
I
E
S
S
L
N
L
V
S
---------
D
------
V
E
R
V
F
I
I
G
G
A
E
I
Y
N
E
L
I
N
N
S
L
V
---
S
H
L
L
I
T
E
I
E
H
P
S
-
P
E
S
I
--
E
M
D
T
F
L
K
-----------------
F
-
P
L
------
E
S
W
T
K
Q
P
K
S
---
E
L
Q
K
F
V
G
D
T
V
--
L
E
D
--------------
D
I
K
--
E
G
D
F
T
Y
N
Y
T
L
W
T
R
K
6
PsiBlast_PDB
97.48
98%
-157
- C3 -
1IA4
3
DYR_CANAX
A:
[1-192]
M
L
K
P
-
N
V
A
I
I
V
A
A
L
K
P
A
L
G
I
G
Y
K
G
K
M
P
W
-
R
L
R
K
E
I
R
Y
F
K
D
V
T
T
R
T
------
T
---
K
P
N
T
R
N
A
V
I
M
G
R
K
T
W
E
S
I
P
Q
K
F
R
P
L
P
D
R
L
N
I
I
L
S
R
S
Y
E
N
E
I
--------------
I
D
D
N
I
I
H
A
S
S
-------
I
E
S
S
L
N
L
V
S
---------
D
------
V
E
R
V
F
I
I
G
G
A
E
I
Y
N
E
L
I
N
N
S
L
V
---
S
H
L
L
I
T
E
I
E
H
P
S
-
P
E
S
I
--
E
M
D
T
F
L
K
-----------------
F
-
P
L
------
E
S
W
T
K
Q
P
K
S
---
E
L
Q
K
F
V
G
D
T
V
--
L
E
D
--------------
D
I
K
--
E
G
D
F
T
Y
N
Y
T
L
W
T
R
K
8
PsiBlast_PDB
97.16
98%
-156
- C3 -
1M79
3
DYR_CANAX
A:
[1-192]
M
L
K
P
-
N
V
A
I
I
V
A
A
L
K
P
A
L
G
I
G
Y
K
G
K
M
P
W
-
R
L
R
K
E
I
R
Y
F
K
D
V
T
T
R
T
------
T
---
K
P
N
T
R
N
A
V
I
M
G
R
K
T
W
E
S
I
P
Q
K
F
R
P
L
P
D
R
L
N
I
I
L
S
R
S
Y
E
N
E
I
--------------
I
D
D
N
I
I
H
A
S
S
-------
I
E
S
S
L
N
L
V
S
---------
D
------
V
E
R
V
F
I
I
G
G
A
E
I
Y
N
E
L
I
N
N
S
L
V
---
S
H
L
L
I
T
E
I
E
H
P
S
-
P
E
S
I
--
E
M
D
T
F
L
K
-----------------
F
-
P
L
------
E
S
W
T
K
Q
P
K
S
---
E
L
Q
K
F
V
G
D
T
V
--
L
E
D
--------------
D
I
K
--
E
G
D
F
T
Y
N
Y
T
L
W
T
R
K
10
PsiBlast_PDB
97.13
98%
-153
- C3 -
3QLR
6
DYR_CANAX
A:
[1-192]
M
L
K
P
-
N
V
A
I
I
V
A
A
L
K
P
A
L
G
I
G
Y
K
G
K
M
P
W
-
R
L
R
K
E
I
R
Y
F
K
D
V
T
T
R
T
------
T
---
K
P
N
T
R
N
A
V
I
M
G
R
K
T
W
E
S
I
P
Q
K
F
R
P
L
P
D
R
L
N
I
I
L
S
R
S
Y
E
N
E
I
--------------
I
D
D
N
I
I
H
A
S
S
-------
I
E
S
S
L
N
L
V
S
---------
D
------
V
E
R
V
F
I
I
G
G
A
E
I
Y
N
E
L
I
N
N
S
L
V
---
S
H
L
L
I
T
E
I
E
H
P
S
-
P
E
S
I
--
E
M
D
T
F
L
K
-----------------
F
-
P
L
------
E
S
W
T
K
Q
P
K
S
---
E
L
Q
K
F
V
G
D
T
V
--
L
E
D
--------------
D
I
K
--
E
G
D
F
T
Y
N
Y
T
L
W
T
R
K
5
PsiBlast_PDB
97.12
98%
-153
- C3 -
1IA3
3
DYR_CANAX
A:
[1-192]
M
L
K
P
-
N
V
A
I
I
V
A
A
L
K
P
A
L
G
I
G
Y
K
G
K
M
P
W
-
R
L
R
K
E
I
R
Y
F
K
D
V
T
T
R
T
------
T
---
K
P
N
T
R
N
A
V
I
M
G
R
K
T
W
E
S
I
P
Q
K
F
R
P
L
P
D
R
L
N
I
I
L
S
R
S
Y
E
N
E
I
--------------
I
D
D
N
I
I
H
A
S
S
-------
I
E
S
S
L
N
L
V
S
---------
D
------
V
E
R
V
F
I
I
G
G
A
E
I
Y
N
E
L
I
N
N
S
L
V
---
S
H
L
L
I
T
E
I
E
H
P
S
-
P
E
S
I
--
E
M
D
T
F
L
K
-----------------
F
-
P
L
------
E
S
W
T
K
Q
P
K
S
---
E
L
Q
K
F
V
G
D
T
V
--
L
E
D
--------------
D
I
K
--
E
G
D
F
T
Y
N
Y
T
L
W
T
R
K
3
PsiBlast_PDB
97.09
98%
-150
- C3 -
1IA1
2
DYR_CANAX
A:
[1-192]
M
L
K
P
-
N
V
A
I
I
V
A
A
L
K
P
A
L
G
I
G
Y
K
G
K
M
P
W
-
R
L
R
K
E
I
R
Y
F
K
D
V
T
T
R
T
------
T
---
K
P
N
T
R
N
A
V
I
M
G
R
K
T
W
E
S
I
P
Q
K
F
R
P
L
P
D
R
L
N
I
I
L
S
R
S
Y
E
N
E
I
--------------
I
D
D
N
I
I
H
A
S
S
-------
I
E
S
S
L
N
L
V
S
---------
D
------
V
E
R
V
F
I
I
G
G
A
E
I
Y
N
E
L
I
N
N
S
L
V
---
S
H
L
L
I
T
E
I
E
H
P
S
-
P
E
S
I
--
E
M
D
T
F
L
K
-----------------
F
-
P
L
------
E
S
W
T
K
Q
P
K
S
---
E
L
Q
K
F
V
G
D
T
V
--
L
E
D
--------------
D
I
K
--
E
G
D
F
T
Y
N
Y
T
L
W
T
R
K
4
PsiBlast_PDB
96.98
98%
-153
- C3 -
1IA2
3
DYR_CANAX
A:
[1-192]
M
L
K
P
-
N
V
A
I
I
V
A
A
L
K
P
A
L
G
I
G
Y
K
G
K
M
P
W
-
R
L
R
K
E
I
R
Y
F
K
D
V
T
T
R
T
------
T
---
K
P
N
T
R
N
A
V
I
M
G
R
K
T
W
E
S
I
P
Q
K
F
R
P
L
P
D
R
L
N
I
I
L
S
R
S
Y
E
N
E
I
--------------
I
D
D
N
I
I
H
A
S
S
-------
I
E
S
S
L
N
L
V
S
---------
D
------
V
E
R
V
F
I
I
G
G
A
E
I
Y
N
E
L
I
N
N
S
L
V
---
S
H
L
L
I
T
E
I
E
H
P
S
-
P
E
S
I
--
E
M
D
T
F
L
K
-----------------
F
-
P
L
------
E
S
W
T
K
Q
P
K
S
---
E
L
Q
K
F
V
G
D
T
V
--
L
E
D
--------------
D
I
K
--
E
G
D
F
T
Y
N
Y
T
L
W
T
R
K
31
PsiBlast_CBE
96.88
98%
-144
- C3 -
1AOE
2
DYR_CANAX
B:
[1-192]
M
L
K
P
-
N
V
A
I
I
V
A
A
L
K
P
A
L
G
I
G
Y
K
G
K
M
P
W
-
R
L
R
K
E
I
R
Y
F
K
D
V
T
T
R
T
------
T
---
K
P
N
T
R
N
A
V
I
M
G
R
K
T
W
E
S
I
P
Q
K
F
R
P
L
P
D
R
L
N
I
I
L
S
R
S
Y
E
N
E
I
--------------
I
D
D
N
I
I
H
A
S
S
-------
I
E
S
S
L
N
L
V
S
---------
D
------
V
E
R
V
F
I
I
G
G
A
E
I
Y
N
E
L
I
N
N
S
L
V
---
S
H
L
L
I
T
E
I
E
H
P
S
-
P
E
S
I
--
E
M
D
T
F
L
K
-----------------
F
-
P
L
------
E
S
W
T
K
Q
P
K
S
---
E
L
Q
K
F
V
G
D
T
V
--
L
E
D
--------------
D
I
K
--
E
G
D
F
T
Y
N
Y
T
L
W
T
R
K
1
PsiBlast_PDB
96.77
98%
-156
- C3 -
1AI9
1
DYR_CANAX
A:
[1-192]
M
L
K
P
-
N
V
A
I
I
V
A
A
L
K
P
A
L
G
I
G
Y
K
G
K
M
P
W
-
R
L
R
K
E
I
R
Y
F
K
D
V
T
T
R
T
------
T
---
K
P
N
T
R
N
A
V
I
M
G
R
K
T
W
E
S
I
P
Q
K
F
R
P
L
P
D
R
L
N
I
I
L
S
R
S
Y
E
N
E
I
--------------
I
D
D
N
I
I
H
A
S
S
-------
I
E
S
S
L
N
L
V
S
---------
D
------
V
E
R
V
F
I
I
G
G
A
E
I
Y
N
E
L
I
N
N
S
L
V
---
S
H
L
L
I
T
E
I
E
H
P
S
-
P
E
S
I
--
E
M
D
T
F
L
K
-----------------
F
-
P
L
------
E
S
W
T
K
Q
P
K
S
---
E
L
Q
K
F
V
G
D
T
V
--
L
E
D
--------------
D
I
K
--
E
G
D
F
T
Y
N
Y
T
L
W
T
R
K
30
PsiBlast_CBE
96.74
98%
-141
- C3 -
1IA1
2
DYR_CANAX
B:
[1-192]
M
L
K
P
-
N
V
A
I
I
V
A
A
L
K
P
A
L
G
I
G
Y
K
G
K
M
P
W
-
R
L
R
K
E
I
R
Y
F
K
D
V
T
T
R
T
------
T
---
K
P
N
T
R
N
A
V
I
M
G
R
K
T
W
E
S
I
P
Q
K
F
R
P
L
P
D
R
L
N
I
I
L
S
R
S
Y
E
N
E
I
--------------
I
D
D
N
I
I
H
A
S
S
-------
I
E
S
S
L
N
L
V
S
---------
D
------
V
E
R
V
F
I
I
G
G
A
E
I
Y
N
E
L
I
N
N
S
L
V
---
S
H
L
L
I
T
E
I
E
H
P
S
-
P
E
S
I
--
E
M
D
T
F
L
K
-----------------
F
-
P
L
------
E
S
W
T
K
Q
P
K
S
---
E
L
Q
K
F
V
G
D
T
V
--
L
E
D
--------------
D
I
K
--
E
G
D
F
T
Y
N
Y
T
L
W
T
R
K
26
PsiBlast_CBE
96.50
98%
-144
- C3 -
1M78
2
DYR_CANAX
B:
[1-192]
M
L
K
P
-
N
V
A
I
I
V
A
A
L
K
P
A
L
G
I
G
Y
K
G
K
M
P
W
-
R
L
R
K
E
I
R
Y
F
K
D
V
T
T
R
T
------
T
---
K
P
N
T
R
N
A
V
I
M
G
R
K
T
W
E
S
I
P
Q
K
F
R
P
L
P
D
R
L
N
I
I
L
S
R
S
Y
E
N
E
I
--------------
I
D
D
N
I
I
H
A
S
S
-------
I
E
S
S
L
N
L
V
S
---------
D
------
V
E
R
V
F
I
I
G
G
A
E
I
Y
N
E
L
I
N
N
S
L
V
---
S
H
L
L
I
T
E
I
E
H
P
S
-
P
E
S
I
--
E
M
D
T
F
L
K
-----------------
F
-
P
L
------
E
S
W
T
K
Q
P
K
S
---
E
L
Q
K
F
V
G
D
T
V
--
L
E
D
--------------
D
I
K
--
E
G
D
F
T
Y
N
Y
T
L
W
T
R
K
35
PsiBlast_CBE
96.39
99%
-156
- C3 -
4H95
2
DYR_CANAX
B:
[1-189]
---
P
-
N
V
A
I
I
V
A
A
L
K
P
A
L
G
I
G
Y
K
G
K
M
P
W
-
R
L
R
K
E
I
R
Y
F
K
D
V
T
T
R
T
------
T
---
K
P
N
T
R
N
A
V
I
M
G
R
K
T
W
E
S
I
P
Q
K
F
R
P
L
P
D
R
L
N
I
I
L
S
R
S
Y
E
N
E
I
--------------
I
D
D
N
I
I
H
A
S
S
-------
I
E
S
S
L
N
L
V
S
---------
D
------
V
E
R
V
F
I
I
G
G
A
E
I
Y
N
E
L
I
N
N
S
L
V
---
S
H
L
L
I
T
E
I
E
H
P
S
-
P
E
S
I
--
E
M
D
T
F
L
K
-----------------
F
-
P
L
------
E
S
W
T
K
Q
P
K
S
---
E
L
Q
K
F
V
G
D
T
V
--
L
E
D
--------------
D
I
K
--
E
G
D
F
T
Y
N
Y
T
L
W
T
R
K
29
PsiBlast_CBE
96.35
98%
-142
- C3 -
1IA2
3
DYR_CANAX
B:
[1-192]
M
L
K
P
-
N
V
A
I
I
V
A
A
L
K
P
A
L
G
I
G
Y
K
G
K
M
P
W
-
R
L
R
K
E
I
R
Y
F
K
D
V
T
T
R
T
------
T
---
K
P
N
T
R
N
A
V
I
M
G
R
K
T
W
E
S
I
P
Q
K
F
R
P
L
P
D
R
L
N
I
I
L
S
R
S
Y
E
N
E
I
--------------
I
D
D
N
I
I
H
A
S
S
-------
I
E
S
S
L
N
L
V
S
---------
D
------
V
E
R
V
F
I
I
G
G
A
E
I
Y
N
E
L
I
N
N
S
L
V
---
S
H
L
L
I
T
E
I
E
H
P
S
-
P
E
S
I
--
E
M
D
T
F
L
K
-----------------
F
-
P
L
------
E
S
W
T
K
Q
P
K
S
---
E
L
Q
K
F
V
G
D
T
V
--
L
E
D
--------------
D
I
K
--
E
G
D
F
T
Y
N
Y
T
L
W
T
R
K
13
PsiBlast_PDB
96.31
99%
-158
- C3 -
4H97
2
DYR_CANAX
A:
[1-190]
--
K
P
-
N
V
A
I
I
V
A
A
L
K
P
A
L
G
I
G
Y
K
G
K
M
P
W
-
R
L
R
K
E
I
R
Y
F
K
D
V
T
T
R
T
------
T
---
K
P
N
T
R
N
A
V
I
M
G
R
K
T
W
E
S
I
P
Q
K
F
R
P
L
P
D
R
L
N
I
I
L
S
R
S
Y
E
N
E
I
--------------
I
D
D
N
I
I
H
A
S
S
-------
I
E
S
S
L
N
L
V
S
---------
D
------
V
E
R
V
F
I
I
G
G
A
E
I
Y
N
E
L
I
N
N
S
L
V
---
S
H
L
L
I
T
E
I
E
H
P
S
-
P
E
S
I
--
E
M
D
T
F
L
K
-----------------
F
-
P
L
------
E
S
W
T
K
Q
P
K
S
---
E
L
Q
K
F
V
G
D
T
V
--
L
E
D
--------------
D
I
K
--
E
G
D
F
T
Y
N
Y
T
L
W
T
R
K
24
PsiBlast_CBE
96.23
98%
-144
- C3 -
1M7A
2
DYR_CANAX
B:
[1-192]
M
L
K
P
-
N
V
A
I
I
V
A
A
L
K
P
A
L
G
I
G
Y
K
G
K
M
P
W
-
R
L
R
K
E
I
R
Y
F
K
D
V
T
T
R
T
------
T
---
K
P
N
T
R
N
A
V
I
M
G
R
K
T
W
E
S
I
P
Q
K
F
R
P
L
P
D
R
L
N
I
I
L
S
R
S
Y
E
N
E
I
--------------
I
D
D
N
I
I
H
A
S
S
-------
I
E
S
S
L
N
L
V
S
---------
D
------
V
E
R
V
F
I
I
G
G
A
E
I
Y
N
E
L
I
N
N
S
L
V
---
S
H
L
L
I
T
E
I
E
H
P
S
-
P
E
S
I
--
E
M
D
T
F
L
K
-----------------
F
-
P
L
------
E
S
W
T
K
Q
P
K
S
---
E
L
Q
K
F
V
G
D
T
V
--
L
E
D
--------------
D
I
K
--
E
G
D
F
T
Y
N
Y
T
L
W
T
R
K
25
PsiBlast_CBE
96.15
98%
-142
- C3 -
1M79
3
DYR_CANAX
B:
[1-192]
M
L
K
P
-
N
V
A
I
I
V
A
A
L
K
P
A
L
G
I
G
Y
K
G
K
M
P
W
-
R
L
R
K
E
I
R
Y
F
K
D
V
T
T
R
T
------
T
---
K
P
N
T
R
N
A
V
I
M
G
R
K
T
W
E
S
I
P
Q
K
F
R
P
L
P
D
R
L
N
I
I
L
S
R
S
Y
E
N
E
I
--------------
I
D
D
N
I
I
H
A
S
S
-------
I
E
S
S
L
N
L
V
S
---------
D
------
V
E
R
V
F
I
I
G
G
A
E
I
Y
N
E
L
I
N
N
S
L
V
---
S
H
L
L
I
T
E
I
E
H
P
S
-
P
E
S
I
--
E
M
D
T
F
L
K
-----------------
F
-
P
L
------
E
S
W
T
K
Q
P
K
S
---
E
L
Q
K
F
V
G
D
T
V
--
L
E
D
--------------
D
I
K
--
E
G
D
F
T
Y
N
Y
T
L
W
T
R
K
27
PsiBlast_CBE
96.10
98%
-141
- C3 -
1IA4
3
DYR_CANAX
B:
[1-192]
M
L
K
P
-
N
V
A
I
I
V
A
A
L
K
P
A
L
G
I
G
Y
K
G
K
M
P
W
-
R
L
R
K
E
I
R
Y
F
K
D
V
T
T
R
T
------
T
---
K
P
N
T
R
N
A
V
I
M
G
R
K
T
W
E
S
I
P
Q
K
F
R
P
L
P
D
R
L
N
I
I
L
S
R
S
Y
E
N
E
I
--------------
I
D
D
N
I
I
H
A
S
S
-------
I
E
S
S
L
N
L
V
S
---------
D
------
V
E
R
V
F
I
I
G
G
A
E
I
Y
N
E
L
I
N
N
S
L
V
---
S
H
L
L
I
T
E
I
E
H
P
S
-
P
E
S
I
--
E
M
D
T
F
L
K
-----------------
F
-
P
L
------
E
S
W
T
K
Q
P
K
S
---
E
L
Q
K
F
V
G
D
T
V
--
L
E
D
--------------
D
I
K
--
E
G
D
F
T
Y
N
Y
T
L
W
T
R
K
33
PsiBlast_CBE
96.05
99%
-152
- C3 -
4H97
3
DYR_CANAX
B:
[1-190]
--
K
P
-
N
V
A
I
I
V
A
A
L
K
P
A
L
G
I
G
Y
K
G
K
M
P
W
-
R
L
R
K
E
I
R
Y
F
K
D
V
T
T
R
T
------
T
---
K
P
N
T
R
N
A
V
I
M
G
R
K
T
W
E
S
I
P
Q
K
F
R
P
L
P
D
R
L
N
I
I
L
S
R
S
Y
E
N
E
I
--------------
I
D
D
N
I
I
H
A
S
S
-------
I
E
S
S
L
N
L
V
S
---------
D
------
V
E
R
V
F
I
I
G
G
A
E
I
Y
N
E
L
I
N
N
S
L
V
---
S
H
L
L
I
T
E
I
E
H
P
S
-
P
E
S
I
--
E
M
D
T
F
L
K
-----------------
F
-
P
L
------
E
S
W
T
K
Q
P
K
S
---
E
L
Q
K
F
V
G
D
T
V
--
L
E
D
--------------
D
I
K
--
E
G
D
F
T
Y
N
Y
T
L
W
T
R
K
14
PsiBlast_PDB
96.02
99%
-156
- C3 -
4H95
2
DYR_CANAX
A:
[1-189]
---
P
-
N
V
A
I
I
V
A
A
L
K
P
A
L
G
I
G
Y
K
G
K
M
P
W
-
R
L
R
K
E
I
R
Y
F
K
D
V
T
T
R
T
------
T
---
K
P
N
T
R
N
A
V
I
M
G
R
K
T
W
E
S
I
P
Q
K
F
R
P
L
P
D
R
L
N
I
I
L
S
R
S
Y
E
N
E
I
--------------
I
D
D
N
I
I
H
A
S
S
-------
I
E
S
S
L
N
L
V
S
---------
D
------
V
E
R
V
F
I
I
G
G
A
E
I
Y
N
E
L
I
N
N
S
L
V
---
S
H
L
L
I
T
E
I
E
H
P
S
-
P
E
S
I
--
E
M
D
T
F
L
K
-----------------
F
-
P
L
------
E
S
W
T
K
Q
P
K
S
---
E
L
Q
K
F
V
G
D
T
V
--
L
E
D
--------------
D
I
K
--
E
G
D
F
T
Y
N
Y
T
L
W
T
R
K
23
PsiBlast_CBE
95.92
98%
-146
- C3 -
3QLR
4
DYR_CANAX
B:
[1-192]
M
L
K
P
-
N
V
A
I
I
V
A
A
L
K
P
A
L
G
I
G
Y
K
G
K
M
P
W
-
R
L
R
K
E
I
R
Y
F
K
D
V
T
T
R
T
------
T
---
K
P
N
T
R
N
A
V
I
M
G
R
K
T
W
E
S
I
P
Q
K
F
R
P
L
P
D
R
L
N
I
I
L
S
R
S
Y
E
N
E
I
--------------
I
D
D
N
I
I
H
A
S
S
-------
I
E
S
S
L
N
L
V
S
---------
D
------
V
E
R
V
F
I
I
G
G
A
E
I
Y
N
E
L
I
N
N
S
L
V
---
S
H
L
L
I
T
E
I
E
H
P
S
-
P
E
S
I
--
E
M
D
T
F
L
K
-----------------
F
-
P
L
------
E
S
W
T
K
Q
P
K
S
---
E
L
Q
K
F
V
G
D
T
V
--
L
E
D
--------------
D
I
K
--
E
G
D
F
T
Y
N
Y
T
L
W
T
R
K
12
PsiBlast_PDB
95.68
98%
-155
- C3 -
3QLW
2
DYR_CANAX
A:
[3-192]
--
K
P
-
N
V
A
I
I
V
A
A
L
K
P
A
L
G
I
G
Y
K
G
K
M
P
W
-
R
L
R
K
E
I
R
Y
F
K
D
V
T
T
R
T
------
T
---
K
P
N
T
R
N
A
V
I
M
G
R
K
T
W
E
S
I
P
Q
K
F
R
P
L
P
D
R
L
N
I
I
L
S
R
S
Y
E
N
E
I
--------------
I
D
D
N
I
I
H
A
S
S
-------
I
E
S
S
L
N
L
V
S
---------
D
------
V
E
R
V
F
I
I
G
G
A
E
I
Y
N
E
L
I
N
N
S
L
V
---
S
H
L
L
I
T
E
I
E
H
P
S
-
P
E
S
I
--
E
M
D
T
F
L
K
-----------------
F
-
P
L
------
E
S
W
T
K
Q
P
K
S
---
E
L
Q
K
F
V
G
D
T
V
--
L
E
D
--------------
D
I
K
--
E
G
D
F
T
Y
N
Y
T
L
W
T
R
K
22
PsiBlast_CBE
95.61
98%
-145
- C3 -
3QLS
5
DYR_CANAX
B:
[1-192]
M
L
K
P
-
N
V
A
I
I
V
A
A
L
K
P
A
L
G
I
G
Y
K
G
K
M
P
W
-
R
L
R
K
E
I
R
Y
F
K
D
V
T
T
R
T
------
T
---
K
P
N
T
R
N
A
V
I
M
G
R
K
T
W
E
S
I
P
Q
K
F
R
P
L
P
D
R
L
N
I
I
L
S
R
S
Y
E
N
E
I
--------------
I
D
D
N
I
I
H
A
S
S
-------
I
E
S
S
L
N
L
V
S
---------
D
------
V
E
R
V
F
I
I
G
G
A
E
I
Y
N
E
L
I
N
N
S
L
V
---
S
H
L
L
I
T
E
I
E
H
P
S
-
P
E
S
I
--
E
M
D
T
F
L
K
-----------------
F
-
P
L
------
E
S
W
T
K
Q
P
K
S
---
E
L
Q
K
F
V
G
D
T
V
--
L
E
D
--------------
D
I
K
--
E
G
D
F
T
Y
N
Y
T
L
W
T
R
K
21
PsiBlast_CBE
95.55
98%
-150
- C3 -
3QLW
2
DYR_CANAX
B:
[3-192]
--
K
P
-
N
V
A
I
I
V
A
A
L
K
P
A
L
G
I
G
Y
K
G
K
M
P
W
-
R
L
R
K
E
I
R
Y
F
K
D
V
T
T
R
T
------
T
---
K
P
N
T
R
N
A
V
I
M
G
R
K
T
W
E
S
I
P
Q
K
F
R
P
L
P
D
R
L
N
I
I
L
S
R
S
Y
E
N
E
I
--------------
I
D
D
N
I
I
H
A
S
S
-------
I
E
S
S
L
N
L
V
S
---------
D
------
V
E
R
V
F
I
I
G
G
A
E
I
Y
N
E
L
I
N
N
S
L
V
---
S
H
L
L
I
T
E
I
E
H
P
S
-
P
E
S
I
--
E
M
D
T
F
L
K
-----------------
F
-
P
L
------
E
S
W
T
K
Q
P
K
S
---
E
L
Q
K
F
V
G
D
T
V
--
L
E
D
--------------
D
I
K
--
E
G
D
F
T
Y
N
Y
T
L
W
T
R
K
28
PsiBlast_CBE
95.24
98%
-139
- C3 -
1IA3
3
DYR_CANAX
B:
[1-192]
M
L
K
P
-
N
V
A
I
I
V
A
A
L
K
P
A
L
G
I
G
Y
K
G
K
M
P
W
-
R
L
R
K
E
I
R
Y
F
K
D
V
T
T
R
T
------
T
---
K
P
N
T
R
N
A
V
I
M
G
R
K
T
W
E
S
I
P
Q
K
F
R
P
L
P
D
R
L
N
I
I
L
S
R
S
Y
E
N
E
I
--------------
I
D
D
N
I
I
H
A
S
S
-------
I
E
S
S
L
N
L
V
S
---------
D
------
V
E
R
V
F
I
I
G
G
A
E
I
Y
N
E
L
I
N
N
S
L
V
---
S
H
L
L
I
T
E
I
E
H
P
S
-
P
E
S
I
--
E
M
D
T
F
L
K
-----------------
F
-
P
L
------
E
S
W
T
K
Q
P
K
S
---
E
L
Q
K
F
V
G
D
T
V
--
L
E
D
--------------
D
I
K
--
E
G
D
F
T
Y
N
Y
T
L
W
T
R
K
32
PsiBlast_CBE
95.00
98%
-140
- C3 -
1AI9
1
DYR_CANAX
B:
[1-192]
M
L
K
P
-
N
V
A
I
I
V
A
A
L
K
P
A
L
G
I
G
Y
K
G
K
M
P
W
-
R
L
R
K
E
I
R
Y
F
K
D
V
T
T
R
T
------
T
---
K
P
N
T
R
N
A
V
I
M
G
R
K
T
W
E
S
I
P
Q
K
F
R
P
L
P
D
R
L
N
I
I
L
S
R
S
Y
E
N
E
I
--------------
I
D
D
N
I
I
H
A
S
S
-------
I
E
S
S
L
N
L
V
S
---------
D
------
V
E
R
V
F
I
I
G
G
A
E
I
Y
N
E
L
I
N
N
S
L
V
---
S
H
L
L
I
T
E
I
E
H
P
S
-
P
E
S
I
--
E
M
D
T
F
L
K
-----------------
F
-
P
L
------
E
S
W
T
K
Q
P
K
S
---
E
L
Q
K
F
V
G
D
T
V
--
L
E
D
--------------
D
I
K
--
E
G
D
F
T
Y
N
Y
T
L
W
T
R
K
15
PsiBlast_PDB
94.91
99%
-156
- C3 -
4H96
2
DYR_CANAX
A:
[1-189]
---
P
-
N
V
A
I
I
V
A
A
L
K
P
A
L
G
I
G
Y
K
G
K
M
P
W
-
R
L
R
K
E
I
R
Y
F
K
D
V
T
T
R
T
------
T
---
K
P
N
T
R
N
A
V
I
M
G
R
K
T
W
E
S
I
P
Q
K
F
R
P
L
P
D
R
L
N
I
I
L
S
R
S
Y
E
N
E
I
--------------
I
D
D
N
I
I
H
A
S
S
-------
I
E
S
S
L
N
L
V
S
---------
D
------
V
E
R
V
F
I
I
G
G
A
E
I
Y
N
E
L
I
N
N
S
L
V
---
S
H
L
L
I
T
E
I
E
H
P
S
-
P
E
S
I
--
E
M
D
T
F
L
K
-----------------
F
-
P
L
------
E
S
W
T
K
Q
P
K
S
---
E
L
Q
K
F
V
G
D
T
V
--
L
E
D
--------------
D
I
K
--
E
G
D
F
T
Y
N
Y
T
L
W
T
R
K
34
PsiBlast_CBE
94.87
99%
-156
- C3 -
4H96
2
DYR_CANAX
B:
[1-189]
---
P
-
N
V
A
I
I
V
A
A
L
K
P
A
L
G
I
G
Y
K
G
K
M
P
W
-
R
L
R
K
E
I
R
Y
F
K
D
V
T
T
R
T
------
T
---
K
P
N
T
R
N
A
V
I
M
G
R
K
T
W
E
S
I
P
Q
K
F
R
P
L
P
D
R
L
N
I
I
L
S
R
S
Y
E
N
E
I
--------------
I
D
D
N
I
I
H
A
S
S
-------
I
E
S
S
L
N
L
V
S
---------
D
------
V
E
R
V
F
I
I
G
G
A
E
I
Y
N
E
L
I
N
N
S
L
V
---
S
H
L
L
I
T
E
I
E
H
P
S
-
P
E
S
I
--
E
M
D
T
F
L
K
-----------------
F
-
P
L
------
E
S
W
T
K
Q
P
K
S
---
E
L
Q
K
F
V
G
D
T
V
--
L
E
D
--------------
D
I
K
--
E
G
D
F
T
Y
N
Y
T
L
W
T
R
K
46
HHSearch
71.47
44%
-135
- C3 -
3CSE
2
?
A:
[3-217]
--
K
V
-
P
V
V
G
I
V
A
A
L
L
P
E
M
G
I
G
F
Q
G
N
L
P
W
-
R
L
A
K
E
M
K
Y
F
R
E
V
T
T
L
T
------
N
---
D
N
S
K
Q
N
V
V
I
M
G
R
K
T
W
E
S
I
P
Q
K
F
R
P
L
P
K
R
I
N
V
V
V
S
R
S
F
D
G
E
L
RK------------
V
E
D
G
I
Y
H
S
N
S
-------
L
R
N
C
L
T
A
L
Q
SSLANEN--
K
------
I
E
R
I
Y
I
I
G
G
G
E
I
Y
R
Q
S
M
--
D
L
A
---
D
H
W
L
I
T
K
I
M
P
L
P
E
T
T
I
P
--
Q
M
D
T
F
L
--------------------
Q
K
------
Q
E
L
E
Q
R
F
Y
D
NSD
K
L
V
D
F
L
P
S
S
I
QL
E
G
R
L
T
S
Q
E
W
NG
E
L
V
K
G
L
P
V
Q
--
E
K
G
Y
Q
F
Y
F
T
L
Y
T
K
K
47
HHSearch
67.14
37%
-126
- C3 -
3NZB
2
DYR_PNECA
X:
[1-205]
M
N
Q
Q
K
S
L
T
L
I
V
A
L
-
T
T
S
Y
G
I
G
R
S
N
S
L
P
W
-
K
L
K
K
E
I
S
Y
F
K
R
V
T
S
F
V
------
P
TFD
S
F
E
S
M
N
V
V
L
M
G
R
K
T
W
E
S
I
P
L
Q
F
R
P
L
K
G
R
I
N
V
V
I
T
R
N
E
S
L
D
L
---------------
G
N
G
I
H
S
A
K
S
-------
L
D
H
A
L
E
L
L
Y
RTYGSESSV
Q
------
I
N
R
I
F
V
I
G
G
A
Q
L
Y
K
A
A
M
D
H
P
K
L
---
D
R
I
M
A
T
I
I
Y
-----
K
D
I
--
H
C
D
V
F
F
P
-----------------
L
-
K
F
RDKEWS
S
V
W
K
K
E
K
H
S
---
D
L
E
S
W
V
G
T
K
V
--
P
H
G
--------------
K
I
N
--
E
D
G
F
D
Y
E
F
E
M
W
T
R
D
19
PsiBlast_PDB
63.31
41%
-118
- C3 -
3EEL
2
?
A:
[3-217]
--
K
V
-
P
V
V
G
I
V
A
A
L
L
P
E
M
G
I
G
F
Q
G
N
L
P
W
-
R
L
A
K
E
M
K
Y
F
R
E
V
T
T
L
T
------
N
---
D
N
S
K
Q
N
V
V
I
M
G
R
K
T
W
E
S
I
P
Q
K
F
R
P
L
P
K
R
I
N
V
V
V
S
R
S
F
D
G
E
L
RK------------
V
E
D
G
I
Y
H
S
N
S
L
R
N
C
L
T
A
L
Q
S
S
L
A
N
E
N
---------
K
------
I
E
R
I
Y
I
I
G
G
G
E
I
Y
R
Q
S
M
D
--
L
A
---
D
H
W
L
I
T
K
I
-
M
P
L
-
P
E
T
T
I
P
Q
M
D
T
F
L
Q
K
Q
E
L
E
Q
R
F
YDNSDKLVD
F
-
L
P
------
S
S
I
Q
L
E
G
R
L
---
T
S
Q
E
W
N
G
E
L
V
--
K
G
L
--------------
P
V
Q
--
E
K
G
Y
Q
F
Y
F
T
L
Y
T
K
K
20
PsiBlast_PDB
63.07
41%
-118
- C3 -
3EEM
2
?
A:
[3-217]
--
K
V
-
P
V
V
G
I
V
A
A
L
L
P
E
M
G
I
G
F
Q
G
N
L
P
W
-
R
L
A
K
E
M
K
Y
F
R
E
V
T
T
L
T
------
N
---
D
N
S
K
Q
N
V
V
I
M
G
R
K
T
W
E
S
I
P
Q
K
F
R
P
L
P
K
R
I
N
V
V
V
S
R
S
F
D
G
E
L
RK------------
V
E
D
G
I
Y
H
S
N
S
L
R
N
C
L
T
A
L
Q
S
S
L
A
N
E
N
---------
K
------
I
E
R
I
Y
I
I
G
G
G
E
I
Y
R
Q
S
M
D
--
L
A
---
D
H
W
L
I
T
K
I
-
M
P
L
-
P
E
T
T
I
P
Q
M
D
T
F
L
Q
K
Q
E
L
E
Q
R
F
YDNSDKLVD
F
-
L
P
------
S
S
I
Q
L
E
G
R
L
---
T
S
Q
E
W
N
G
E
L
V
--
K
G
L
--------------
P
V
Q
--
E
K
G
Y
Q
F
Y
F
T
L
Y
T
K
K
17
PsiBlast_PDB
62.95
41%
-118
- C3 -
3EEJ
2
?
A:
[3-217]
--
K
V
-
P
V
V
G
I
V
A
A
L
L
P
E
M
G
I
G
F
Q
G
N
L
P
W
-
R
L
A
K
E
M
K
Y
F
R
E
V
T
T
L
T
------
N
---
D
N
S
K
Q
N
V
V
I
M
G
R
K
T
W
E
S
I
P
Q
K
F
R
P
L
P
K
R
I
N
V
V
V
S
R
S
F
D
G
E
L
RK------------
V
E
D
G
I
Y
H
S
N
S
L
R
N
C
L
T
A
L
Q
S
S
L
A
N
E
N
---------
K
------
I
E
R
I
Y
I
I
G
G
G
E
I
Y
R
Q
S
M
D
--
L
A
---
D
H
W
L
I
T
K
I
-
M
P
L
-
P
E
T
T
I
P
Q
M
D
T
F
L
Q
K
Q
E
L
E
Q
R
F
YDNSDKLVD
F
-
L
P
------
S
S
I
Q
L
E
G
R
L
---
T
S
Q
E
W
N
G
E
L
V
--
K
G
L
--------------
P
V
Q
--
E
K
G
Y
Q
F
Y
F
T
L
Y
T
K
K
18
PsiBlast_PDB
62.94
41%
-118
- C3 -
3EEK
2
?
A:
[3-217]
--
K
V
-
P
V
V
G
I
V
A
A
L
L
P
E
M
G
I
G
F
Q
G
N
L
P
W
-
R
L
A
K
E
M
K
Y
F
R
E
V
T
T
L
T
------
N
---
D
N
S
K
Q
N
V
V
I
M
G
R
K
T
W
E
S
I
P
Q
K
F
R
P
L
P
K
R
I
N
V
V
V
S
R
S
F
D
G
E
L
RK------------
V
E
D
G
I
Y
H
S
N
S
L
R
N
C
L
T
A
L
Q
S
S
L
A
N
E
N
---------
K
------
I
E
R
I
Y
I
I
G
G
G
E
I
Y
R
Q
S
M
D
--
L
A
---
D
H
W
L
I
T
K
I
-
M
P
L
-
P
E
T
T
I
P
Q
M
D
T
F
L
Q
K
Q
E
L
E
Q
R
F
YDNSDKLVD
F
-
L
P
------
S
S
I
Q
L
E
G
R
L
---
T
S
Q
E
W
N
G
E
L
V
--
K
G
L
--------------
P
V
Q
--
E
K
G
Y
Q
F
Y
F
T
L
Y
T
K
K
50
HHSearch
58.31
32%
-120
- C3 -
3RG9
2
DRTS_TRYBB
A:
[29-239]
------
F
S
V
V
V
A
S
-
D
E
K
G
G
I
G
D
G
G
T
I
P
W
-
E
I
P
E
D
M
Q
Y
F
R
R
V
T
T
N
L
RGKNVK
P
---
S
P
S
K
R
N
A
V
V
M
G
R
K
T
W
D
S
L
P
P
K
F
R
P
L
S
N
R
L
N
V
V
L
S
R
S
A
T
K
E
Q
L
L
A
G
IPD
P
I
K
R
A
E
A
A
N
D
V
V
A
V
N
G
G
-------
L
E
D
A
L
R
M
L
V
---------
S
K
E
H
T
S
S
I
E
T
V
F
C
I
G
G
G
T
I
Y
K
Q
A
L
C
A
P
C
V
N
V
L
Q
A
I
H
R
T
V
V
R
P
----
A
S
N
--
S
C
S
V
F
F
D
-----------------
I
-
P
A
------
A
G
--
T
K
T
P
E
---
G
L
E
-
L
V
R
E
S
I
--
T
D
E
--------------
R
V
S
TG
A
G
G
K
K
Y
Q
F
E
K
L
V
P
R
51
HHSearch
58.03
37%
-134
- C3 -
1KMV
2
DYR_HUMAN
A:
[3-185]
-----
S
L
N
C
I
V
A
V
-
S
Q
N
M
G
I
G
K
N
G
D
L
P
W
P
P
L
R
N
E
F
R
Y
F
Q
R
M
T
T
T
S
------
S
---
V
E
G
K
Q
N
L
V
I
M
G
K
K
T
W
F
S
I
P
E
K
N
R
P
L
K
G
R
I
N
L
V
L
S
R
E
L
K
E
P
P
---------------
Q
G
A
H
F
L
S
R
S
-------
L
D
D
A
L
K
L
T
E
---------
Q
PELANK
V
D
M
V
W
I
V
G
G
S
S
V
Y
K
E
A
M
N
H
P
G
H
---
L
K
L
F
V
T
R
I
M
-----
Q
D
F
--
E
S
D
T
F
F
P
E
----------------
I
-
D
L
------
E
K
Y
K
L
L
P
E
--------
Y
P
G
--
V
--
L
S
D
--------------
V
Q
E
--
E
K
G
I
K
Y
K
F
E
V
Y
E
K
N
61
HHSearch
53.29
34%
-119
- C3 -
3S9U
2
?
A:
[5-164]
-----
R
V
S
F
M
V
A
M
-
D
E
N
R
V
I
G
K
D
N
N
L
P
W
-
R
L
P
S
E
L
Q
Y
V
K
K
T
T
M
----------------
G
H
P
L
I
M
G
R
K
N
Y
E
A
I
G
---
R
P
L
P
G
R
R
N
I
I
V
T
R
N
E
G
Y
H
----------------
V
E
G
C
E
V
A
H
S
-------
V
E
E
V
F
E
L
C
K
---------
N
------
E
E
E
I
F
I
F
G
G
A
Q
I
Y
D
L
F
L
--
P
Y
V
---
D
K
L
Y
I
T
K
I
H
-----
H
A
F
--
E
G
D
T
F
F
P
-----------------
E
M
D
M
------
T
N
W
K
E
V
F
V
E
---------------
K
G
L
--------------
T
D
E
--
K
N
P
Y
T
Y
Y
Y
H
V
Y
E
K
Q