@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Wbm0063: (2015-11-28 )
MINEEVVKENLKEVIERKSGKDVIALGIISSIVIKGKDIGFVLEISGDTQANEELRKNCEKAVKAIPGVGKVTVVAAGRKQAGQQRAKLHIEGVKNIIVVASGKGGVGKSTVALNLAFSLAKLKHKVALVDADIYGPSIPKMLGAEKLKPKIQGSRIIPIEKYGLHTISIGYFIDKDCAAMWRGPMITKALYNLLMGTKWSDIEYLVVDTPPGTGDVHLSLMENFNLTGGIIVSTPQELALVDARKIYNMFTKLSVPIFGIVENMSYFIQDNSKIYIFGKDGTKVMSEELGIKLLGRIPLDPKICYASDCGNPLMLSEDLAGIYEDFAKDIRSFI
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100........110.......120.......130.......140..-------.....150--.------...-----...---.-.160--.........-170...-...-..180---------.......190....--....200.......210.---......220........230.......240.......-250...--------....----260..-.....270.--.......280.-......-290.......300.......310......--.---320.......330-----....--
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MI
N
E
E
V
V
K
E
N
L
K
E
V
I
E
RKSGK
D
V
I
A
L
G
I
I
S
S
I
V
I
KGKD
I
G
F
V
L
E
ISGDTQ
A
N
E
E
L
R
K
N
C
E
K
A
V
K
AIPGV
G
K
V
T
V
V
AAG
R
K
Q
A
G
Q
Q
R
A
K
L
H
I
EGV
K
N
I
I
V
V
A-SGKGGVGK
S
T
V
A
L
N
L
A
F
S
L
A
K
L
K
H
K
V
A
L
V
D
ADIYGPS
I
P
K
M
L
G
-------
A
E
KLKP----K------IQG-----
S
R
I
---
I
-
P
I
----EKYG
L
H
T
I
S
-
I
-
G
Y
F
I-DK
D
-
C
A
A
MW---------RG
P
M
I
T
K
A
-
L
Y
N
L
L
--MGTKWSD
I
E
Y
L
V
V
DTPPG---TG
D
V
H
L
S
L
-
M
ENFNLTG
G
I
I
VS
T
P
Q
E
L
A
L
V
D
A
R
K
I
Y
N
-
M
F
T
K
LS--------
V
P
I
F
----
G
I
V
E
N
-
M
S
Y
F
IQD-N--
S
K
I
Y
I
FGKDG
T
-
K
V
M
S
E
E-L
G
I
K
L
LGRIPLDPK
I
C
Y
ASDCGN
P
L
M
L
S
E
--
D
---
L
A
G
I
Y
E
D
F
A
K
D
I
------
R
S
FI--
1
PsiBlast_PDB
89.12
34%
-112
- C1 -
2PH1
1
?
A:
[4-240]
--------------------------------------------------------------------------------
R
V
T
D
E
E
I
K
E
R
L
G
K
I
K
S
R
I
A
V
M
-
S
G
K
G
G
V
G
K
S
T
V
T
A
L
L
A
V
H
Y
A
R
Q
G
K
K
V
G
I
L
D
A
D
F
L
G
P
S
I
P
I
L
F
G
-------
L
R
N
A
R
I
----
A
------
V
S
A
-----
E
G
L
---
E
-
P
V
L
T
--
Q
K
Y
G
I
K
V
M
S
-
M
-
Q
F
L
L
-
P
K
E
N
T
P
V
I
W
---------
R
G
P
L
I
A
G
M
-
I
R
E
F
L
--
G
R
V
A
W
G
E
L
D
H
L
L
I
D
L
P
P
G
---
T
G
D
A
P
L
T
V
-
M
Q
D
A
K
P
T
G
V
V
V
V
S
T
P
Q
E
L
T
A
V
I
V
E
K
A
I
N
-
M
A
E
E
T
N
--------
T
S
V
L
----
G
L
V
E
N
-
M
S
Y
F
V
C
P
-
N
CG
H
K
S
Y
I
F
G
E
G
K
G
-
E
S
L
A
K
K
-
Y
N
I
G
F
F
T
S
I
P
I
E
E
E
L
I
K
L
A
D
S
G
R
I
E
E
Y
E
K
--
D
---
W
F
E
---------------------
7
PsiBlast_PDB
88.33
35%
-123
- C1 -
5AUQ
1
?
A:
[14-222]
-----------------------------------------------------------------------------------------
R
L
E
G
V
K
R
I
I
P
V
V
-
S
G
K
G
G
V
G
K
S
L
V
S
T
T
L
A
L
V
L
A
E
K
G
Y
R
V
G
L
L
D
L
D
F
H
G
A
S
D
H
V
I
L
G
-------
F
E
P
K
E
F
----
P
------
E
E
D
-----
R
G
V
---
V
-
P
P
----
T
V
H
G
I
K
F
M
T
-
I
-
A
Y
Y
T
---------
L
---------
R
G
K
E
I
S
D
A
-
L
I
E
L
L
--
T
I
T
R
W
D
E
L
D
Y
L
V
I
D
M
P
P
G
---
L
G
D
Q
L
L
D
V
-
L
R
F
L
K
R
G
E
F
L
V
V
A
T
P
S
K
L
S
L
N
V
V
R
K
L
I
E
-
L
L
K
E
E
G
--------
H
K
V
I
----
G
V
V
E
N
-
M
K
L
-----
R
---------
K
D
V
E
-
K
-
L
A
E
E
-
F
G
V
P
Y
L
V
G
I
P
F
Y
P
D
L
D
A
K
V
G
N
V
E
E
L
M
K
T
E
--
F
---
A
G
K
V
R
E
L
A
G
R
L
-------------
2
PsiBlast_PDB
88.18
34%
-114
- C1 -
3KB1
3
?
A:
[4-240]
--------------------------------------------------------------------------------
R
V
T
D
E
D
I
K
E
R
L
D
K
I
G
F
R
I
A
V
M
-
S
G
K
G
G
V
G
K
S
T
V
T
A
L
L
A
V
H
Y
A
K
Q
G
K
K
V
G
I
L
D
A
D
F
L
G
P
S
I
P
H
L
F
G
-------
L
E
K
G
K
V
----
A
------
V
S
D
-----
E
G
L
---
E
-
P
V
LT--
Q
R
L
G
I
K
V
M
S
-
I
-
Q
F
L
L
----------------------
L
I
A
G
M
-
I
R
E
F
L
--
G
R
V
A
W
G
E
L
D
Y
L
L
I
D
L
P
P
G
---
T
G
D
A
P
L
T
V
-
M
Q
D
A
K
P
N
G
A
V
I
V
S
T
P
Q
E
L
T
A
A
V
V
E
K
A
I
T
-
M
A
E
Q
T
K
--------
T
A
V
L
----
G
I
V
E
N
-
M
A
Y
F
E
C
P
-
N
CG
E
R
T
Y
L
F
G
E
G
K
A
-
S
E
L
A
R
K
-
Y
K
I
E
F
I
T
E
I
P
I
D
S
D
L
L
K
L
S
D
L
G
R
V
E
E
Y
E
P
--
D
---
W
F
E
F
F
P
Y
L
E
H
H
-------------
21
PsiBlast_CBE
88.00
35%
-126
- C1 -
5AUQ
1
?
D:
[14-222]
-----------------------------------------------------------------------------------------
R
L
E
G
V
K
R
I
I
P
V
V
-
S
G
K
G
G
V
G
K
S
L
V
S
T
T
L
A
L
V
L
A
E
K
G
Y
R
V
G
L
L
D
L
D
F
H
G
A
S
D
H
V
I
L
G
-------
F
E
P
K
E
F
----
P
------
E
E
D
-----
R
G
V
---
V
-
P
P
----
T
V
H
G
I
K
F
M
T
-
I
-
A
Y
Y
T
--------
P
L
---------
R
G
K
E
I
S
D
A
-
L
I
E
L
L
--
T
I
T
R
W
D
E
L
D
Y
L
V
I
D
M
P
P
G
---
L
G
D
Q
L
L
D
V
-
L
R
F
L
K
R
G
E
F
L
V
V
A
T
P
S
K
L
S
L
N
V
V
R
K
L
I
E
-
L
L
K
E
E
G
--------
H
K
V
I
----
G
V
V
E
N
-
M
K
L
---------------
K
D
V
E
-
K
-
L
A
E
E
-
F
G
V
P
Y
L
V
G
I
P
F
Y
P
D
L
D
A
K
V
G
N
V
E
E
L
M
K
T
E
--
F
---
A
G
K
V
R
E
L
A
G
R
L
-------------
3
PsiBlast_PDB
86.76
35%
-123
- C1 -
3VX3
5
?
A:
[14-222]
-----------------------------------------------------------------------------------------
R
L
E
G
V
K
R
I
I
P
V
V
-
S
G
K
G
G
V
G
K
S
L
V
S
T
T
L
A
L
V
L
A
E
K
G
Y
R
V
G
L
L
D
L
D
F
H
G
A
S
D
H
V
I
L
G
-------
F
E
P
K
E
F
----
P
------
E
E
D
-----
R
G
V
---
V
-
P
P
----
T
V
H
G
I
K
F
M
T
-
I
-
A
Y
Y
T
-------
T
P
L
---------
R
G
K
E
I
S
D
A
-
L
I
E
L
L
--
T
I
T
R
W
D
E
L
D
Y
L
V
I
D
M
P
P
G
---
L
G
D
Q
L
L
D
V
-
L
R
F
L
K
R
G
E
F
L
V
V
A
T
P
S
K
L
S
L
N
V
V
R
K
L
I
E
-
L
L
K
E
E
G
--------
H
K
V
I
----
G
V
V
E
N
-
M
K
L
-----
R
--------
E
K
D
V
E
-
K
-
L
A
E
E
-
F
G
V
P
Y
L
V
G
I
P
F
Y
P
D
L
D
A
K
V
G
N
V
E
E
L
M
K
T
E
--
F
---
A
G
K
V
R
E
L
A
G
R
L
-------------
25
PsiBlast_CBE
86.61
35%
-124
- C1 -
3VX3
7
?
B:
[14-222]
-----------------------------------------------------------------------------------------
R
L
E
G
V
K
R
I
I
P
V
V
-
S
G
K
G
G
V
G
K
S
L
V
S
T
T
L
A
L
V
L
A
E
K
G
Y
R
V
G
L
L
D
L
D
F
H
G
A
S
D
H
V
I
L
G
-------
F
E
P
K
E
F
----
P
------
E
E
D
-----
R
G
V
---
V
-
P
P
----
T
V
H
G
I
K
F
M
T
-
I
-
A
Y
Y
T
-------
T
P
L
---------
R
G
K
E
I
S
D
A
-
L
I
E
L
L
--
T
I
T
R
W
D
E
L
D
Y
L
V
I
D
M
P
P
G
---
L
G
D
Q
L
L
D
V
-
L
R
F
L
K
R
G
E
F
L
V
V
A
T
P
S
K
L
S
L
N
V
V
R
K
L
I
E
-
L
L
K
E
E
G
--------
H
K
V
I
----
G
V
V
E
N
-
M
K
L
-----
R
--------
E
K
D
V
E
-
K
-
L
A
E
E
-
F
G
V
P
Y
L
V
G
I
P
F
Y
P
D
L
D
A
K
V
G
N
V
E
E
L
M
K
T
E
--
F
---
A
G
K
V
R
E
L
A
G
R
L
-------------
22
PsiBlast_CBE
86.15
35%
-126
- C1 -
5AUQ
1
?
C:
[14-222]
-----------------------------------------------------------------------------------------
R
L
E
G
V
K
R
I
I
P
V
V
-
S
G
K
G
G
V
G
K
S
L
V
S
T
T
L
A
L
V
L
A
E
K
G
Y
R
V
G
L
L
D
L
D
F
H
G
A
S
D
H
V
I
L
G
-------
F
E
P
K
E
F
----
P
------
E
E
D
-----
R
G
V
---
V
-
P
P
----
T
V
H
G
I
K
F
M
T
-
I
-
A
Y
Y
T
--------
P
L
---------
R
G
K
E
I
S
D
A
-
L
I
E
L
L
--
T
I
T
R
W
D
E
L
D
Y
L
V
I
D
M
P
P
G
---
L
G
D
Q
L
L
D
V
-
L
R
F
L
K
R
G
E
F
L
V
V
A
T
P
S
K
L
S
L
N
V
V
R
K
L
I
E
-
L
L
K
E
E
G
--------
H
K
V
I
----
G
V
V
E
N
-
M
K
L
----------------
D
V
E
-
K
-
L
A
E
E
-
F
G
V
P
Y
L
V
G
I
P
F
Y
P
D
L
D
A
K
V
G
N
V
E
E
L
M
K
T
E
--
F
---
A
G
K
V
R
E
L
A
G
R
L
-------------
23
PsiBlast_CBE
85.86
35%
-125
- C1 -
5AUQ
1
?
B:
[14-222]
-----------------------------------------------------------------------------------------
R
L
E
G
V
K
R
I
I
P
V
V
-
S
G
K
G
G
V
G
K
S
L
V
S
T
T
L
A
L
V
L
A
E
K
G
Y
R
V
G
L
L
D
L
D
F
H
G
A
S
D
H
V
I
L
G
-------
F
E
P
K
E
F
----
P
---------------
G
V
---
V
-
P
P
----
T
V
H
G
I
K
F
M
T
-
I
-
A
Y
Y
T
--------
P
L
---------
R
G
K
E
I
S
D
A
-
L
I
E
L
L
--
T
I
T
R
W
D
E
L
D
Y
L
V
I
D
M
P
P
G
---
L
G
D
Q
L
L
D
V
-
L
R
F
L
K
R
G
E
F
L
V
V
A
T
P
S
K
L
S
L
N
V
V
R
K
L
I
E
-
L
L
K
E
E
G
--------
H
K
V
I
----
G
V
V
E
N
-
M
K
L
---------------
K
D
V
E
-
K
-
L
A
E
E
-
F
G
V
P
Y
L
V
G
I
P
F
Y
P
D
L
D
A
K
V
G
N
V
E
E
L
M
K
T
E
--
F
---
A
G
K
V
R
E
L
A
G
R
L
-------------
5
PsiBlast_PDB
84.98
35%
-117
- C1 -
5AUO
4
?
B:
[14-222]
-----------------------------------------------------------------------------------------
R
L
E
G
V
K
R
I
I
P
V
V
-
S
G
K
G
G
V
G
K
S
L
V
S
T
T
L
A
L
V
L
A
E
K
G
Y
R
V
G
L
L
D
L
D
F
H
G
A
S
D
H
V
I
L
G
-------
F
E
P
K
E
F
----
P
------
E
E
D
-----
R
G
V
---
V
-
P
P
----
T
V
H
G
I
K
F
M
T
-
I
-
A
Y
Y
T
-
E
-
D
-
R
P
T
P
L
---------
R
G
K
E
I
S
D
A
-
L
I
E
L
L
--
T
I
T
R
W
D
E
L
D
Y
L
V
I
D
M
P
P
G
---
L
G
D
Q
L
L
D
V
-
L
R
F
L
K
R
G
E
F
L
V
V
A
T
P
S
K
L
S
L
N
V
V
R
K
L
I
E
-
L
L
K
E
E
G
--------
H
K
V
I
----
G
V
V
E
N
-
M
K
L
---------------
K
D
V
E
-
K
-
L
A
E
E
-
F
G
V
P
Y
L
V
G
I
P
F
Y
P
D
L
D
A
K
V
G
N
V
E
E
L
M
K
T
E
--
F
---
A
G
K
V
R
E
L
A
G
R
L
-------------
6
PsiBlast_PDB
84.41
35%
-118
- C1 -
5AUP
3
?
B:
[14-222]
-----------------------------------------------------------------------------------------
R
L
E
G
V
K
R
I
I
P
V
V
-
S
G
K
G
G
V
G
K
S
L
V
S
T
T
L
A
L
V
L
A
E
K
G
Y
R
V
G
L
L
D
L
D
F
H
G
A
S
D
H
V
I
L
G
-------
F
E
P
K
E
F
----
P
------
E
E
D
-----
R
G
V
---
V
-
P
P
----
T
V
H
G
I
K
F
M
T
-
I
-
A
Y
Y
T
-
E
-
D
-
R
P
T
P
L
---------
R
G
K
E
I
S
D
A
-
L
I
E
L
L
--
T
I
T
R
W
D
E
L
D
Y
L
V
I
D
M
P
P
G
---
L
G
D
Q
L
L
D
V
-
L
R
F
L
K
R
G
E
F
L
V
V
A
T
P
S
K
L
S
L
N
V
V
R
K
L
I
E
-
L
L
K
E
E
G
--------
H
K
V
I
----
G
V
V
E
N
-
M
K
L
---------------
K
D
V
E
-
K
-
L
A
E
E
-
F
G
V
P
Y
L
V
G
I
P
F
Y
P
D
L
D
A
K
V
G
N
V
E
E
L
M
K
T
E
--
F
---
A
G
K
V
R
E
L
A
G
R
L
-------------
24
PsiBlast_CBE
84.03
35%
-113
- C1 -
5AUP
3
?
I:
[14-222]
-----------------------------------------------------------------------------------------
R
L
E
G
V
K
R
I
I
P
V
V
-
S
G
K
G
G
V
G
K
S
L
V
S
T
T
L
A
L
V
L
A
E
K
G
Y
R
V
G
L
L
D
L
D
F
H
G
A
S
D
H
V
I
L
G
-------
F
E
P
K
E
F
----
P
------
E
E
D
-----
R
G
V
---
V
-
P
P
----
T
V
H
G
I
K
F
M
T
-
I
-
A
Y
Y
T
-
E
-
D
-
R
P
T
P
L
---------
R
G
K
E
I
S
D
A
-
L
I
E
L
L
--
T
I
T
R
W
D
E
L
D
Y
L
V
I
D
M
P
P
G
---
L
G
D
Q
L
L
D
V
-
L
R
F
L
K
R
G
E
F
L
V
V
A
T
P
S
K
L
S
L
N
V
V
R
K
L
I
E
-
L
L
K
E
E
G
--------
H
K
V
I
----
G
V
V
E
N
-
M
K
L
-----
R
---------
K
D
V
E
-
K
-
L
A
E
E
-
F
G
V
P
Y
L
V
G
I
P
F
Y
P
D
L
D
A
K
V
G
N
V
E
E
L
M
K
T
E
--
F
---
A
G
K
V
R
E
L
A
G
R
L
-------------
4
PsiBlast_PDB
83.75
35%
-116
- C1 -
5AUN
4
?
B:
[14-222]
-----------------------------------------------------------------------------------------
R
L
E
G
V
K
R
I
I
P
V
V
-
S
G
K
G
G
V
G
K
S
L
V
S
T
T
L
A
L
V
L
A
E
K
G
Y
R
V
G
L
L
D
L
D
F
H
G
A
S
D
H
V
I
L
G
-------
F
E
P
K
E
F
----
P
------
E
E
D
-----
R
G
V
---
V
-
P
P
----
T
V
H
G
I
K
F
M
T
-
I
-
A
Y
Y
T
-
E
-
D
-
R
P
T
P
L
---------
R
G
K
E
I
S
D
A
-
L
I
E
L
L
--
T
I
T
R
W
D
E
L
D
Y
L
V
I
D
M
P
P
G
---
L
G
D
Q
L
L
D
V
-
L
R
F
L
K
R
G
E
F
L
V
V
A
T
P
S
K
L
S
L
N
V
V
R
K
L
I
E
-
L
L
K
E
E
G
--------
H
K
V
I
----
G
V
V
E
N
-
M
K
L
---------------
K
D
V
E
-
K
-
L
A
E
E
-
F
G
V
P
Y
L
V
G
I
P
F
Y
P
D
L
D
A
K
V
G
N
V
E
E
L
M
K
T
E
--
F
---
A
G
K
V
R
E
L
A
G
R
L
-------------
144
HHSearch
81.00
35%
-90
- C1 -
2PH1
1
?
A:
[15-247]
-------------------------------------------------------------------------------------------
G
K
I
K
S
R
I
A
V
M
-
S
G
K
G
G
V
G
K
S
T
V
T
A
L
L
A
V
H
Y
A
R
Q
G
K
K
V
G
I
L
D
A
D
F
L
G
P
S
I
P
I
L
F
G
-------
L
R
N
A
R
I
A
V
S
A
E
------
G
L
E
-----
P
V
L
---
T
-
Q
K
YGI
K
V
M
S
M
Q
F
L
L
P
-
K
-
E
N
T
-------
P
V
I
W
---------
R
G
P
L
I
A
G
M
-
I
R
E
F
L
--
G
R
V
A
W
G
E
L
D
H
L
L
I
D
L
P
P
G
---
T
G
D
A
P
L
T
V
-
M
Q
D
A
K
P
T
G
V
V
V
V
S
T
P
Q
E
L
T
A
V
I
V
E
K
A
I
N
-
M
A
E
E
T
N
--------
T
S
V
L
----
G
L
V
E
N
-
M
S
Y
F
V
C
P
-
N
CG
H
K
S
Y
I
F
G
E
G
K
G
-
E
S
L
A
K
K
-
Y
N
I
G
F
F
T
S
I
P
I
E
E
E
L
I
K
L
A
D
S
G
R
I
E
E
Y
E
K
--
D
---
W
F
E
---------------------
160
Fugue
79.21
30%
-89
- C1 -
2PH1
1
?
A:
[4-250]
--------------------------------------------------------------------------------
R
V
T
D
E
E
I
K
E
R
L
G
K
I
K
S
R
I
A
V
-
M
S
G
K
G
G
V
G
K
S
T
V
T
A
L
L
A
V
H
Y
A
R
Q
G
K
K
V
G
I
L
D
A
D
F
L
G
P
S
I
P
I
L
F
G
-------
L
R
N
A
R
I
----
A
------
V
S
A
-----
E
G
L
---
E
-
P
V
----
L
T
Q
K
Y
G
I
K
V
M
S
M
Q
F
L
L
P
K
E
N
-
T
P
V
I
W
---------
R
G
P
L
I
A
-
G
M
I
R
E
F
L
--
G
R
V
A
W
G
E
L
D
H
L
L
I
D
L
P
P
G
---
T
G
D
A
P
L
T
V
M
Q
D
A
-
K
P
T
G
V
V
V
V
S
T
P
Q
E
L
T
A
V
I
V
E
K
A
I
N
M
A
-
E
E
T
N
--------
T
S
V
L
----
G
L
V
E
N
M
S
Y
F
V
C
P
N
C
G
--
H
K
S
Y
I
F
G
E
G
K
G
-
E
S
L
A
K
K
-
Y
N
I
G
F
F
T
S
I
P
I
E
E
E
L
I
K
L
A
D
S
G
R
I
E
E
Y
E
K
--
D
---
W
F
E
---------------------
163
Fugue
78.88
26%
-90
- C1 -
3Q9L
3
MIND_ECOLI
A:
[2-258]
----------------------------------------------------------------------------------------------
A
R
I
I
V
V
T
-
S
G
K
G
G
V
G
K
T
T
S
S
A
A
I
A
T
G
L
A
Q
K
G
K
K
T
V
V
I
D
F
A
I
G
L
R
N
L
D
L
I
M
G
-------
C
E
R
R
V
V
-------------------
Y
D
F
---
V
-
N
V
----
I
Q
-
G
D
A
T
L
N
-
Q
-
A
L
I
K
-
D
K
R
-
T
E
N
L
Y
I
L
P
A
S
QTRD
K
D
A
L
T
R
E
G
-
V
A
K
V
L
--
D
D
L
K
A
M
D
F
E
F
I
V
C
D
S
P
A
G
---
I
E
T
G
A
L
M
A
-
L
Y
F
A
D
--
E
A
I
I
T
T
N
P
E
V
S
S
V
R
D
S
D
R
I
L
G
-
I
L
A
S
K
S
--------
R
R
A
E
N
GEE
P
I
K
E
H
-
L
L
L
T
R
Y
N
-
P
--
G
R
V
S
R
G
D
M
L
S
M
-
E
D
V
L
E
I
-
L
R
I
K
L
V
G
V
I
P
E
D
Q
S
V
L
R
A
S
N
Q
G
E
P
V
I
L
D
I
NA
D
---
A
G
K
A
Y
A
D
T
V
E
R
L
L
G
E
E
R
P
F
R
F
I
EE
12
PsiBlast_PDB
77.07
27%
-102
- C2 -
4RZ3
2
?
A:
[29-252]
---------------------------------------------------------------------------------------------
S
P
R
T
I
A
V
T
-
S
G
K
G
G
V
G
K
S
N
V
S
L
N
F
S
L
S
L
S
K
L
G
F
R
V
L
L
L
D
M
A
I
G
M
G
N
I
D
I
L
L
G
ESSSLA
L
A
D
W
F
S
A
----
R
------
L
P
L
-----
S
E
L
---
V
--------
K
S
G
P
E
H
L
S
----
Y
I
A
-
G
G
T
-
G
A
A
Q
W
---------
Q
G
-
L
D
T
A
S
-
I
D
R
F
L
T
E
L
Q
A
V
A
S
Q
Y
D
Y
L
I
F
D
M
G
A
G
---
A
S
G
E
R
L
Y
F
-
L
K
S
V
D
D
V
--
F
V
V
T
T
P
E
P
T
A
M
T
D
A
Y
A
M
M
K
Y
M
H
A
A
G
S
--------
E
A
P
F
----
S
V
I
V
N
-
R
A
G
K
E
R
E
-
G
--
Y
E
V
F
E
R
L
K
H
V
T
G
R
F
L
N
K
D
---
I
A
L
L
G
I
I
P
E
D
R
T
V
A
R
A
V
V
S
Q
T
P
F
V
L
L
D
--
P
---
A
A
K
A
S
K
A
V
R
Q
M
A
------
F
R
Y
A
--
138
HHSearch
76.65
23%
-103
- C1 -
1G3Q
2
?
A:
[2-236]
----------------------------------------------------------------------------------------------
G
R
I
I
S
I
V
-
S
G
K
G
G
T
G
K
T
T
V
T
A
N
L
S
V
A
L
G
D
R
G
R
K
V
L
A
V
D
G
D
L
T
M
A
N
L
S
L
V
L
G
-------
V
D
D
P
D
V
T
L
H
-
D
V
L
A
GEA
N
V
E
-----
D
A
I
---
Y
-
M
T
----
Q
F
D
N
V
Y
V
L
P
-
G
-
A
V
D
W
-
E
H
V
-
L
K
---------------
A
D
P
R
K
-
L
P
E
V
I
--
K
S
L
K
-
D
K
F
D
F
I
L
I
D
C
P
A
G
---
L
Q
L
D
A
M
S
A
-
M
--
L
S
G
E
E
A
L
L
V
T
N
P
E
I
S
C
L
T
D
T
M
K
V
G
I
-
V
L
K
K
A
G
--------
L
A
I
L
----
G
F
V
L
N
-
R
Y
G
R
S
D
R
-
D
------
I
----
P
P
-
E
A
A
E
D
V
-
M
E
V
P
L
L
A
V
I
P
E
D
P
A
I
R
E
G
T
L
E
G
I
P
A
V
K
Y
K
--
P
ES
K
G
A
K
A
F
V
K
L
A
E
E
I
------
E
K
L
A
--
11
PsiBlast_PDB
75.49
28%
-114
- C1 -
1HYQ
-
?
A:
[5-214]
-------------------------------------------------------------------------------------------------
I
T
V
A
-
S
G
K
G
G
T
G
K
T
T
I
T
A
N
L
G
V
A
L
A
Q
L
G
H
D
V
T
I
V
D
A
D
I
T
M
A
N
L
E
L
I
L
G
-------
M
E
G
L
P
V
----
T
------
L
Q
N
V
L
A
GE
A
R
I
DEA
I
-
Y
V
----
G
P
G
G
V
K
V
V
P
-
A
-
G
V
S
L
-
E
G
L
-
R
K
A
------------
N
P
E
K
L
E
D
-
V
L
T
Q
I
--
M
--
E
S
T
D
I
--
L
L
L
D
A
P
A
G
LE
R
S
A
V
I
A
I
A
A
-
A
Q
E
L
-----
L
L
V
V
N
P
E
I
S
S
I
T
D
G
L
K
T
K
I
-
V
A
E
R
L
G
--------
T
K
V
L
----
G
V
V
V
N
-------------
R
I
T
T
L
G
I
E
M
A
-
K
N
E
I
E
A
I
L
E
A
K
V
I
G
L
I
P
E
D
P
E
V
R
R
A
A
A
Y
G
K
P
V
V
L
R
S
--
P
---
N
S
P
A
A
R
A
I
V
E
L
A
------
N
Y
I
A
--
143
HHSearch
74.40
25%
-84
* C1 *
3Q9L
3
MIND_ECOLI
A:
[2-249]
----------------------------------------------------------------------------------------------
A
R
I
I
V
V
T
-
S
G
K
G
G
V
G
K
T
T
S
S
A
A
I
A
T
G
L
A
Q
K
G
K
K
T
V
V
I
D
F
A
I
G
L
R
N
L
D
L
I
M
G
-------
C
E
R
R
V
V
YD
F
V
N
V
I
Q
GDA
T
L
N
-----
Q
A
L
---
I
K
D
K
----
R
T
E
N
L
Y
I
L
P
-
A
-
S
Q
T
R
-
D
K
D
-----------------
A
L
T
R
E
G
-
V
A
K
V
L
--
D
D
L
K
A
M
D
F
E
F
I
V
C
D
S
P
A
G
---
I
E
T
G
A
L
M
A
-
L
Y
F
--
A
D
E
A
I
I
T
T
N
P
E
V
S
S
V
R
D
S
D
R
I
L
G
-
I
L
A
S
K
S
R
R
A
E
N
GEE
P
I
K
E
----
H
L
L
L
T
-
R
Y
N
P
G
R
V
-
S
--
R
G
D
-
M
---
L
S
M
-
E
D
V
L
E
I
-
L
R
I
K
L
V
G
V
I
P
E
D
Q
S
V
L
R
A
S
N
Q
G
E
P
V
I
L
D
I
--
N
A
D
-
A
G
K
A
Y
A
D
T
V
E
R
L
------
L
G
E
E
--
140
HHSearch
73.75
26%
-98
- C1 -
1HYQ
-
?
A:
[2-233]
----------------------------------------------------------------------------------------------
V
R
T
I
T
V
A
-
S
G
K
G
G
T
G
K
T
T
I
T
A
N
L
G
V
A
L
A
Q
L
G
H
D
V
T
I
V
D
A
D
I
T
M
A
N
L
E
L
I
L
G
-------
M
E
G
L
P
V
T
L
Q
-
N
V
L
A
GEA
R
I
D
-----
E
A
I
---
Y
--
V
----
G
P
G
G
V
K
V
V
P
-
A
-
G
V
S
L
-
E
G
L
-
R
---------------
K
A
N
P
E
K
-
L
E
D
V
L
--
T
Q
I
M
-
E
S
T
D
I
L
L
L
D
A
P
A
G
---
L
E
R
S
A
V
I
A
-
I
A
A
--
A
Q
E
L
L
L
V
V
N
P
E
I
S
S
I
T
D
G
L
K
T
K
I
-
V
A
E
R
L
G
--------
T
K
V
L
----
G
V
V
V
N
-
R
I
T
T
L
G
I
-
E
-----
M
-----
A
K
-
N
E
I
E
A
I
-
L
E
A
K
V
I
G
L
I
P
E
D
P
E
V
R
R
A
A
A
Y
G
K
P
V
V
L
R
S
--
P
NS
P
A
A
R
A
I
V
E
L
A
N
Y
I
------
A
-----