@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SA0037: (2016-03-11 )
MKYDDFIVGETFKTKSLHITEEEIIQFATTFDPQYMHIDKEKAEQSRFKGIIASGMHTLSISFKLWVEEGKYGEEVVAGTQMNNVKFIKPVYPGNTLYVIAEITNKKSIKKENGLVTVSLSTYNENEEIVFKGEVTALINNS
Atome Classification :
(20 SA)
------.......--..10..-.-.....20..-..---...-.-30.-........40...-....-.50........60.-...--....70.---..-....-..80........90........---100.....--..110.-----...----.--....120...-.------....130.....-..140---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
------MKYD
D
F
I
--VG
E
T
FK-T-KSLHI
T
E
E
E
-
I
I
---
Q
F
A
-T-T-F-DPQ
Y
M
HI
D
K
E
K
A
E
-
Q
S
R
F
-
K
G
I
I
ASG
M
H
T
L
S
I
S
-
F
K
L
--
W
V
EEG-K---YG-E
E
V
V-AGTQMNN
V
K
F
I
K
PVYPG
N
T
L
Y
V
---
I
A
EITNKK--SIK--K-----EN
G
----
L
--
V
T
V
S
L
-STYN-E------NE
E
I
V
FKG
E
V
T
A
-
L
INNS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
HHSearch
78.14
22%
-73
- C3 -
3K67
1
?
A:
[31-159]
------
K
F
E
G
E
L
K
--
E
G
Y
R
F
E
---
Y
E
K
K
L
C
E
I
D
-
V
A
---
M
F
G
-
L
-
I
S
G
-
D
L
N
P
V
H
F
D
E
D
F
A
S
-
K
T
R
F
-
G
G
R
V
V
H
G
M
L
T
T
S
L
V
-
S
A
A
--
V
A
R
L
------
P
G
-
T
--
V
--
V
L
L
E
Q
S
F
R
Y
T
S
P
V
R
I
G
D
V
V
R
V
---
E
G
V
V
S
G
V
E
--
K
------------
N
----
R
--
Y
T
I
D
V
-
K
C
Y
T
--------
G
D
K
V
V
A
E
G
V
V
K
V
-
L
I
W
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
73.86
24%
-66
- C3 -
4FFU
-
?
A:
[31-162]
--------
Y
E
D
Y
E
--
Q
G
H
V
R
L
-
T
-
S
G
R
T
I
T
E
T
D
F
V
V
---
H
A
G
-
H
-
T
-
G
-
D
F
F
P
H
H
M
D
A
E
F
A
K
-
T
L
P
G
-
G
Q
R
I
A
H
G
T
M
I
F
S
I
G
-
V
G
L
--
T
A
----
S
---
L
I
-
N
P
V
A
-
F
S
Y
G
Y
D
R
L
R
F
V
R
P
V
H
I
G
D
T
I
R
T
---
R
V
T
I
A
A
K
E
--
D
D
P
--
K
-----
R
P
G
----
A
G
R
V
V
E
R
C
-
E
V
I
N
-
Q
------
R
G
E
V
V
L
A
A
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
73.82
28%
-21
- C3 -
3EXZ
-
?
A:
[16-157]
------
L
F
L
E
D
L
A
--
V
G
D
R
F
D
-
S
-
A
R
H
R
V
E
A
A
A
-
I
K
---
A
F
A
-
G
-
E
-
F
-
D
P
Q
P
F
H
L
D
E
E
A
A
R
-
H
S
L
F
-
G
G
L
A
A
S
G
W
H
T
A
A
I
T
-
M
R
L
--
L
V
T
S
G
-
L
---
P
L
-
A
Q
G
I
--
I
G
A
G
T
E
L
S
W
P
N
P
T
R
P
G
D
E
L
H
V
---
E
T
T
V
L
A
I
T
--
P
S
K
SR
P
-----
D
R
A
----
I
--
V
T
C
Q
S
-
D
T
L
N
-
Q
------
R
G
E
V
V
Q
R
S
T
A
K
V
-
V
V
F
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
45
Fugue
71.43
21%
-81
* C3 *
4W78
2
?
B:
[1-126]
----------
M
T
V
--
V
G
A
V
L
P
-
E
-
L
K
L
Y
G
D
P
T
F
-
I
V
---
S
T
A
-
L
A
T
-
R
-
D
F
Q
D
V
H
H
D
R
D
K
A
V
-
A
Q
G
S
-
K
D
I
F
V
N
I
L
T
D
T
G
L
V
-
Q
R
Y
--
V
T
D
W
A
-
G
---
P
S
------
A
L
I
K
S
I
G
L
R
L
G
V
P
W
Y
A
Y
D
T
V
T
F
---
S
G
E
V
T
A
V
N
--------------
D
G
----
L
--
I
T
V
K
V
-
V
G
R
N
-
T
------
L
G
D
H
V
-
T
A
T
V
E
L
-
S
M
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
71.17
34%
-23
- C3 -
3EXZ
-
?
A:
[19-146]
---------
E
D
L
A
--
V
G
D
R
F
D
-
S
-
A
R
H
R
V
E
A
A
A
-
I
K
---
A
F
A
-
G
-
E
-
F
-
D
P
Q
P
F
H
L
D
E
E
A
A
R
-
H
S
L
F
-
G
G
L
A
A
S
G
W
H
T
A
A
I
T
-
M
R
L
--
L
V
T
S
G
L
P
---
L
A
-
Q
G
I
I
G
A
G
T
E
L
S
---
W
P
N
P
T
R
P
G
D
E
L
H
V
E
T
T
V
L
A
I
T
P
S
K
--
S
-
R
--
P
-----
D
R
A
----
I
--
V
T
C
Q
S
-
D
T
L
N
-
Q
------
R
G
E
V
V
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
48
Fugue
67.34
23%
-62
- C3 -
2F3X
2
FAPR_BACSU
A:
[13-155]
ELS
I
P
E
L
R
E
R
I
K
N
--
V
A
E
K
T
L
-
E
-
D
E
V
K
S
L
S
L
D
-
E
V
IGE
I
I
D
-
L
-
E
-
L
-
D
D
Q
A
I
S
I
L
E
I
K
Q
E
-
H
V
F
S
-
R
N
Q
I
A
R
G
H
H
L
F
A
Q
A
-
N
S
L
--
A
V
A
-------
V
I
-
D
D
E
L
-
A
L
T
A
S
A
D
I
R
F
T
R
Q
V
K
Q
G
E
R
V
V
A
---
K
A
K
V
T
A
V
E
-------
K
-----
E
K
G
----
R
--
T
V
V
E
V
-
N
S
Y
V
--------
G
E
E
I
V
F
S
G
R
F
D
M
-
Y
R
S
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
67.26
29%
-11
- C3 -
1Q6W
-
?
A:
[13-157]
------
I
Y
F
E
S
I
Q
--
I
G
E
K
I
E
-
G
-
L
P
R
T
V
T
E
T
D
-
I
W
---
T
F
A
-
Y
-
L
T
A
-
D
F
F
P
L
H
T
D
V
E
F
A
K
-
K
T
I
F
-
G
K
P
I
A
Q
G
M
L
V
L
S
I
A
-
L
G
M
--
V
D
Q
V
I
-
L
S
N
Y
D
V
-
S
S
V
I
-
A
F
F
G
I
K
D
V
R
F
L
R
P
V
F
I
G
D
T
I
A
A
---
S
A
E
V
V
E
K
Q
--
D
F
D
--
E
-----
K
S
G
----
V
--
V
T
Y
K
L
-
E
V
K
N
-
Q
------
R
G
E
L
V
L
T
A
L
Y
S
A
-
L
I
R
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
66.53
30%
-20
- C3 -
1Q6W
-
?
A:
[20-158]
---------------
I
G
E
K
I
E
-
G
-
L
P
R
T
V
T
E
T
D
-
I
W
---
T
F
A
Y
L
-
T
-
A
-
D
F
F
P
L
H
T
D
V
E
F
A
K
-
K
T
I
F
-
G
K
P
I
A
Q
G
M
L
V
L
S
I
A
-
L
G
M
V
D
Q
V
I
L
S
-
N
---
Y
D
V
S
S
V
I
-
A
F
F
G
I
K
D
V
R
F
L
R
P
V
F
I
G
D
T
I
A
A
---
S
A
E
V
V
E
K
Q
--
D
F
D
--
E
-----
K
S
G
----
V
--
V
T
Y
K
L
-
E
V
K
N
-
Q
------
R
G
E
L
V
L
T
A
L
Y
S
A
-
L
I
R
K
T
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
66.18
20%
-71
- C3 -
1IQ6
1
PHAJ_AERCA
A:
[3-134]
--------
A
Q
S
L
E
--
V
G
Q
K
A
R
---
L
S
K
R
F
G
A
A
E
-
V
A
---
A
F
A
-
A
-
L
S
E
-
D
F
N
P
L
H
L
D
P
A
F
A
A
-
T
T
A
F
-
E
R
P
I
V
H
G
M
L
L
A
S
L
F
-
S
G
L
--
L
G
Q
Q
------
L
P
-
G
K
G
S
--
I
Y
L
G
Q
S
L
S
F
K
L
P
V
F
V
G
D
E
V
T
A
---
E
V
E
V
T
A
L
R
--
E
D
----------
K
P
----
I
--
A
T
L
T
T
-
R
I
F
T
-
Q
------
G
G
A
L
A
V
T
G
E
A
V
V
-
K
L
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
44
Fugue
65.18
19%
-73
- C3 -
1IQ6
1
PHAJ_AERCA
A:
[3-134]
--------
A
Q
S
L
E
--
V
G
Q
K
A
R
-
L
-
S
K
R
-
F
G
A
A
E
-
V
A
---
A
F
A
-
A
-
L
-
S
E
D
F
N
P
L
H
L
D
P
A
F
A
A
-
T
T
A
F
-
E
R
P
I
V
H
G
M
L
L
A
S
L
F
-
S
G
L
--
L
G
Q
Q
--
L
---
P
G
-
K
G
S
I
-
Y
L
G
Q
--
S
L
S
F
K
L
P
V
F
V
G
D
E
V
T
A
---
E
V
E
V
T
A
L
R
-------
E
-----
D
K
P
----
I
--
A
T
L
T
T
-
R
I
F
T
-
Q
------
G
G
A
L
A
V
T
G
E
A
V
V
-
K
L
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
HHSearch
65.10
14%
-71
- C3 -
2BI0
1
?
A:
[13-158]
------
P
Y
F
D
D
L
S
--
K
G
Q
V
F
D
-
W
A
P
G
V
T
L
S
L
G
L
-
A
A
---
A
H
Q
-
S
-
I
V
G
-
N
R
L
R
L
A
L
D
S
D
L
C
A
A
V
T
G
M
-
P
G
P
L
A
H
P
G
L
V
C
D
V
A
-
I
G
Q
--
S
T
L
A
------
T
Q
--
R
V
K
-
A
N
L
F
Y
R
G
L
R
F
H
R
F
P
A
V
G
D
T
L
Y
T
---
R
T
E
V
V
G
L
R
--
A
N
S
--
P
KPGR
A
P
T
G
----
L
--
A
G
L
R
M
-
T
T
I
D
-
R
------
T
D
R
L
V
L
D
F
Y
R
C
A
-
M
L
P
A
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
HHSearch
64.69
22%
-92
- C3 -
1PN2
1
FOX2_CANTR
A:
[167-275]
--------------------------
V
P
V
-
S
E
D
-
L
A
---
A
L
Y
-
R
-
L
S
G
-
D
R
N
P
L
H
I
D
P
N
F
A
K
-
G
A
K
F
-
P
K
P
I
L
H
G
M
C
T
Y
G
L
S
-
A
K
A
--
L
I
D
K
------
F
G
-------
M
F
N
E
I
K
A
R
F
T
G
I
V
F
P
G
E
T
L
R
V
---
L
A
W
K
E
S
----------------
D
D
----
T
--
I
V
F
Q
T
-
H
V
V
D
--------
R
G
T
I
A
I
N
N
A
A
I
K
-
L
V
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
HHSearch
64.40
22%
-83
- C3 -
3KH8
-
?
A:
[178-293]
--------------------------
E
F
K
T
S
P
H
-
Q
A
---
Q
V
Y
-
R
-
L
S
G
-
D
Y
N
S
L
H
I
D
P
E
I
A
K
-
S
V
G
F
-
K
Q
P
I
L
H
G
L
C
S
M
G
V
A
-
S
R
A
--
L
F
K
Q
--
F
---
C
G
-
G
D
V
--
A
R
F
K
S
I
R
V
R
F
S
S
P
C
F
P
G
E
T
I
Q
T
---
R
M
W
Q
E
G
S
----------------
G
----
K
--
V
L
F
Q
A
--
V
V
K
-
E
------
R
G
A
V
I
V
D
G
G
E
F
V
-
Y
T
Q
D
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
43
Fugue
63.39
25%
-1
- C3 -
3EXZ
-
?
A:
[15-160]
-----G
L
F
L
E
D
L
A
--
V
G
D
R
F
D
-
S
-
A
R
H
R
V
E
A
A
A
-
I
K
---
A
F
A
-
G
-
E
-
F
-
D
P
Q
P
F
H
L
D
E
E
A
A
R
-
H
S
L
F
-
G
G
L
A
A
S
G
W
H
T
A
A
I
T
M
R
L
L
--
V
T
S
G
L
-
P
---
L
A
-
Q
G
---
I
I
G
A
G
T
E
L
S
W
P
N
P
T
R
P
G
D
E
L
H
V
---
E
T
T
V
L
A
I
T
P
S
K
S
R
--
P
-----
D
R
A
----
I
--
V
T
C
Q
S
-
D
T
L
N
-
Q
------
R
G
E
V
V
Q
R
S
T
A
K
V
-
V
V
F
R
R
PL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
HHSearch
63.24
22%
-81
- C3 -
1S9C
-
DHB4_HUMAN
A:
[179-289]
----------------------------
T
T
S
L
N
-
Q
A
---
A
L
Y
-
R
-
L
S
G
-
D
W
N
P
L
H
I
D
P
N
F
A
S
-
L
A
G
F
-
D
K
P
I
L
H
G
L
C
T
F
G
F
S
-
A
R
R
--
V
L
Q
Q
------
F
A
-
D
N
D
V
-
S
R
F
K
A
V
K
A
R
F
A
K
P
V
Y
P
G
Q
T
L
Q
T
---
E
M
W
K
E
G
-----------------
N
----
R
--
I
H
F
Q
T
-
K
V
Q
--
E
------
T
G
D
I
V
I
S
N
A
Y
V
D
-
L
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
HHSearch
62.59
24%
-29
- C3 -
2C2I
-
ECH1_MYCTU
A:
[5-149]
------
E
S
V
A
D
L
A
A
A
A
G
E
K
V
G
-
Q
S
D
W
V
T
I
T
Q
E
E
-
V
N
---
L
F
A
-
D
-
A
T
G
-
D
H
Q
W
I
H
V
D
P
E
R
A
A
-
A
G
P
F
-
G
T
T
I
A
H
G
F
M
T
L
A
L
L
-
P
R
L
--
Q
H
Q
M
Y
-
T
V
--
K
G
-
V
K
L
A
-
I
N
Y
G
L
N
K
V
R
F
P
A
P
V
P
V
G
S
R
V
R
A
---
T
S
S
L
V
G
V
E
--
D
L
G
--
N
-----
G
T
V
----
Q
--
A
T
V
S
T
-
T
V
E
V
E
G
------
S
A
K
P
A
C
V
A
E
S
I
V
-
R
Y
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
HHSearch
61.26
19%
-69
- C3 -
2UV8
-
?
G:
[1526-1640]
--------------------------
D
S
Y
T
P
S
T
-
N
E
---
P
Y
A
-
R
-
V
S
G
-
D
L
N
P
I
H
V
S
R
H
F
A
S
-
Y
A
N
L
-
P
G
T
I
T
H
G
M
F
S
S
A
S
V
-
R
A
L
--
I
E
N
W
------
A
A
-
D
S
V
S
-
S
R
V
R
G
Y
T
C
Q
F
V
D
M
V
L
P
N
T
A
L
K
T
---
S
I
Q
H
V
G
M
I
--
N
------------
G
----
R
--
K
L
I
K
F
-
E
T
R
N
-
E
------
D
D
V
V
V
L
T
G
E
A
E
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
42
Fugue
60.98
14%
-56
- C3 -
2BI0
1
?
A:
[8-337]
-IRVGG
P
Y
F
D
D
L
S
--
K
G
Q
V
F
D
W
A
-
P
G
V
T
L
S
L
G
L
-
A
A
---
A
H
Q
-
S
-
I
-
V
G
N
R
L
R
L
A
L
D
S
D
L
C
A
-
A
V
T
G
M
P
G
P
L
A
H
P
G
L
V
C
D
V
A
-
I
G
Q
--
S
T
L
-------
A
T
-
Q
R
V
K
-
A
N
L
F
Y
R
G
L
R
F
H
R
F
P
A
V
G
D
T
L
Y
T
---
R
T
E
V
V
G
L
R
--
A
N
S
--
P
-----
K
P
G
R
A
P
T
G
--
L
A
G
L
R
M
T
T
I
D
-
R
------
T
D
R
L
V
L
D
F
Y
R
C
A
M
L
P
A
S
P
DWKPGAVPGDDLSRIGADAPAPAADPTAHWD
G
A
V
F
R
K
R
VPGPHFDAGIAG
A
V
L
H
S
T
A
D
L
VSG
A
P
E
L
A
R
L
T
LNIAATHHDWRVSGRRLVY
G
G
H
T
I
G
L
A
L
A
Q
A
T
R
L
L
PNLATVL
D
W
E
S
CDHT
A
P
V
H
EG
D
T
L
Y
S
E
L
H
IE
S
A
Q
A
H
AD
G
G
V
L
G
L
R
S
L
V
Y
A
V
S
DSAS
E
P
D
R
Q
V
L
D
W
R
F
S
A
L
Q
F
27
HHSearch
60.18
20%
-77
- C3 -
3IR3
1
HTD2_HUMAN
A:
[14-144]
---------
M
H
I
K
--
V
G
D
R
A
E
---
L
R
R
A
F
T
Q
T
D
-
V
A
---
T
F
S
-
E
-
L
T
G
-
D
V
N
P
L
H
L
N
E
D
F
----------
T
I
V
H
G
V
L
I
N
G
L
I
-
S
A
L
--
L
G
T
K
--
M
---
P
G
--
P
G
--
C
V
F
L
S
Q
E
I
S
F
P
A
P
L
Y
I
G
E
V
V
L
A
---
S
A
E
V
K
K
L
K
--
R
F
----------
I
A
----
I
--
I
A
V
S
C
-
S
V
I
--
E
------
S
K
K
T
V
M
E
G
W
V
K
V
-
M
V
P
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
HHSearch
57.96
15%
-56
- C3 -
2BI0
-
?
A:
[203-336]
-------
H
F
D
A
-
G
--
I
A
G
A
V
L
H
S
-
T
A
D
L
V
S
G
A
P
-
E
L
-----
A
-
R
-
L
T
L
-
N
I
A
A
T
H
H
D
W
R
V
S
-------
G
R
R
L
V
Y
G
G
H
T
I
G
L
A
-
L
A
Q
--
A
T
R
L
------
L
P
--
N
L
A
-
T
V
L
D
W
E
S
C
D
H
T
A
P
V
H
E
G
D
T
L
Y
S
---
E
L
H
I
E
S
A
Q
--
A
H
A
--------
D
G
G
----
V
--
L
G
L
R
S
-
L
V
Y
A
-
V
S
DSAS
E
P
D
R
Q
V
L
D
W
R
F
S
A
-
L
Q
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------