@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo0453: (2016-03-15 )
MLKKRLLLASRWIIMLIIYAGLWTYTLFQGDTASWFLTYFFSFILLLLFLSSIYPLKAWKVNRSFVKNTYHDGDLIDMQVSFTRKSRYPVGYLLFQQKIPATFGKVRARQQVVYPLFKKQFTVTLAGFVGVRGIHSFPPVDVETSDAFGLLERSRQLSSEKSLTIYPTYFPNVLEKISEASPENERNAAYWTLKKNSNLHSLREFSSGDRISLIDWKSSAKSDQLMTREFENSATSRLSVIFYGASHPNFELSLRAAYSFIRKISEENGEIRVTLLGDQTSKFAPAKGTSRLQDISTAFAEIAPVDSLTLQESLDSNLHSGEKILLFTPCMDTMLMQKVTRLTDNKQLQIITFQSEHSKAMDAPAIFLEQASLLSRWERETK
Atome Classification :
(20 SA)
-----------------------------------------------------------------------------.........10........20.--.......-30--........40----...---------------------------------------.----.....50.----..-----..---...60.----.......70.----------------------.......80....-.--...90....---.----...100.......110......---.120.......130.......140.......150.......160......-------------.170..----.......---------180.....-..190.......200-.........-----210.......220--.......230-----........240..------....-----.---.--250------.------.-----.......260...--.--...270.......280.......290.......300.....--.----.-310-...----.-----..--.----------.----------.320.....-...330-----------...--------------.-----....340.---.---...--..350-......-.360.......370.......380-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-----------------------------------------------------------------------------ML
K
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LFQ-GD--
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F
-----
F
S
F
---------------------------------------
I
----
L
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SS----IY-----PL---
K
A
W
K
V
N
----
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S
F
V
KNTYHD----------------------G
D
L
I
D
M
Q
V
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F
TRK-S--RYPV
G
Y
L
L
F
---Q----QKI
P
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---
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GVRGIHSFPPVDVET
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QLSSEK
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I
YPT-------------Y
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--
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----
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E---------ASPENER
N
-
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LKKNSN
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---
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EFSSG
D
-----
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DWKSSAKS--
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E------NSAT
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-
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------GASH-----P---
N
--
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--------
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------
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LGDQTSKFAPAKGT
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S--N----------L----------HSG-
E
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-FTP
C
M
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--------------
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-----
M
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LT---D---NK
Q
--
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-FQSEHS-KAMDA
P
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L
L
S
R
W
ERETK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
Fugue
83.31
20%
-55
* C4 *
4K7J
4
?
A:
[26-375]
---------------------------------------------------------------------------GL
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A
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
Fugue
76.67
16%
-47
- C6 -
4NOM
-
LGMN_MOUSE
A:
[26-432]
----------------------------------------------------------------------------------
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NSEEN
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CL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
Fugue
72.30
19%
-68
* C6 *
4AW9
7
LGMN_HUMAN
A:
[1-263]
------------------------------------------------------------------------------------
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GIP
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--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
Fugue
68.45
14%
-57
- C2 -
1D2M
4
UVRB_THET8
A:
[2-583]
--------------------------TFRYRGPSPKGD
Q
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GERFVTLLGATGTG
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V------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
Fugue
65.12
17%
-67
- C4 -
4TQ3
3
?
A:
[15-301]
-----------------------------------------------------------------------------
S
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--------------------------------------------------------------------------
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-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
55.19
13%
-68
- C3 -
1ATZ
-
VWF_HUMAN
A:
[926-1066]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
L
D
V
I
L
L
-
L
D
------
G
S
S
S
-----
F
P
A
S
Y
--
F
--------
D
------
E
-----
M
K
S
F
A
K
A
F
I
S
K
A
N
IG
P
--
R
L
T
Q
V
S
V
L
Q
Y
G
S
I
T
T
I
D
V
P
W
N
V
V
P
E
K
A
H
L
L
S
L
V
D
V
M
Q
R
E
G
G
--
P
SQ
I
G
D
-
A
---
L
G
F
----
A
-----
V
R
--
Y
----------
L
TSEMHGARPG
A
S
K
-
A
V
V
I
L
-
V
T
D
V
S
------------
V
D
S
--------------
V
-----
D
A
A
A
D
A
A
R
---
S
---
N
R
V
--
T
V
F
P
I
G
I
G
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
HHSearch
54.17
10%
-76
- C3 -
1YVR
-
RO60_XENLA
A:
[366-503]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
T
G
K
R
F
L
L
A
-
I
D
------
V
S
A
S
-----
M
---
N
--
Q
--------
R
VLGSIL
N
-----
A
S
V
V
A
A
A
M
C
M
L
V
A
--
R
--
T
E
K
D
S
H
M
V
A
F
S
D
E
M
L
P
C
-
P
I
T
V
N
M
L
L
H
E
V
V
E
K
M
S
D
-
I
T
M
G
S
--
T
D
C--
A
L
P
---
M
L
W
----
A
-----
Q
K
--
T
----------
N
----------
T
A
A
-
D
I
F
I
V
-
F
T
D
C
E
------------
T
N
V
EDVH----------
P
-----
A
T
A
L
K
Q
Y
R
---
E
K
--
M
G
I
P
A
K
L
I
V
C
A
M
T
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
54.12
7%
-74
- C3 -
1PT6
2
ITA1_HUMAN
A:
[7-149]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
L
D
I
V
I
V
-
L
D
------
G
S
N
S
-----
I
Y--
P
--
W
--------
D
------
S
-----
V
T
A
F
L
N
D
L
L
K
R
M
D
IG
P
--
K
Q
T
Q
V
G
I
V
Q
Y
G
E
N
V
T
H
E
F
N
L
N
K
Y
S
S
T
E
E
V
L
V
A
A
K
K
I
V
Q
R
G
G
RQ
T
M
T
A
-
L
G
T
D
T
A
R
K
E
----
A
FTEAR
G
A
--
R
----------
R
----------
G
V
K
-
K
V
M
V
I
-
V
T
D
G
E
------------
S
H
D
NHR-----------
L
-----
K
K
V
I
Q
D
C
E
---
D
---
E
N
I
--
Q
R
F
S
I
A
I
L
G
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
HHSearch
48.88
7%
-52
- C3 -
2NVO
1
RO60_DEIRA
A:
[332-500]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
G
K
G
T
W
L
P
V
P
R
V
--
V
D
A
L
E
E
A
F
T
L
A
FGNV
Q
P
A
N
T
R
H
L
L
A
-
L
D
------
V
S
G
S
-----
M
---
T
--
C
G
D
V
AGVPG
L
------
T
-----
P
N
M
A
A
A
A
M
S
L
I
A
L
--
R
--
T
E
P
D
A
L
T
M
G
F
A
E
Q
F
R
P
L
-
G
I
T
P
R
D
T
L
E
S
A
M
Q
K
A
Q
S
-
V
S
F
G
G
--
T
D
C
--
A
Q
P
---
I
L
W
----
A
-----
A
Q
--
E
----------
R
----------
L
D
V
-
D
T
F
V
V
-
Y
T
D
N
E
------------
T
W
A
G
QVH----------
P
-----
T
V
A
L
D
Q
Y
A
---
Q
K
MG
R
A
P
--
K
L
I
V
V
G
L
T
A
T
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
Fugue
46.66
16%
-44
- C1 -
3RFU
3
?
A:
[74-736]
VSP
E
Y
L
D
M
R
R
R
F
W
I
A
L
M
L
T
I
P
V
V
I
L
E
M
G
GHGLKHFISGNG
S
S
W
I
Q
L
L
L
A
T
P
V
V
LWGG
W
P
F
F
K
R
G
W
Q
S
L
K
TGQLN
M
F
T
L
I
A
M
G
I
G
V
A
W
I
Y
S
M
V
A
V
L
W
P
G
V
--
F
P
H
A
F
R
S
-
Q
E
--
G
V
V
A
V
Y
F
E
A
-----
A
A
V
---------------------------------------
I
----
T
T
L
V
L
L
G
Q
----
V
L
-----
E
L
---
K
A
R
E
Q
T
GS
A
I
R
A
L
L
K
L
V
P
E
S
----------------------
A
H
R
I
K
E
D
G
S
E
E
E
V
-
S
LD
N
V
A
V
G
D
L
L
R
V
R
P
G
----
E
K
I
P
V
D
-
G
E
V
Q
E
G
R
S
F
V
D
E
--------------------
S
M
V
T
G
E
P
I
P
V
A
K
E
A
S
A
K
V
I
G
A
T
I
N
Q
T
G
S
F
V
M
K
A
L
H
V
-------------
G
S
--
D
T
----
M
L
A
R
I
V
Q
---------
M
V
S
D
A
Q
R
S
R
A
P
I
Q
R
L
A
D
T
V
S
G
W
---
F
V
P
A
V
I
L
V
A
-----
V
L
S
F
I
V
W
A
L
L
G
P
Q
--
P
A
L
-----
S
------
Y
G
L
I
A
A
V
S
V
L
-
I
I
------
A
C
P
-----------------------------
C
-----
A
L
G
L
A
T
P
M
S
I
M
V
G
--
V
--
G
K
G
A
Q
S
G
V
L
I
K
N
-----------------
A
E
A
L
E
R
M
E
K
V
N
T
--
L
----
V
-
V
---
D
K
T
-----------
G
--
T
----------
L
----------
T
E
G
-
H
-------
P
K
L
------------
T
R
I
--------------
V
-----
T
D
D
F
V
E
D
N
---
A
---
L
A
L
--
A
A
A
L
E
-
H
Q
S
E
H
P
-
L
A
N
A
I
V
H
A
A
K
E
K
G
L
S
L
G
S
V
E
A
F
E
A
P
TGK
G
V
V
G
Q
V
DGH
H
V
A
I
G
N
A
R
L
M
Q
E
H
G
G
D
N
A
P
L
F
E
K
A
D
E
L
R
G
K
GA
S
V
M
F
M
A
V
DGKTV
A
L
L
V
V
E
DPIKSS
T
P
E
T
I
L
E
L
Q
Q
S
G
I
E
I
V
M
L
T
G
D
S
K
R
T
A
E
A
V
A
G
T
L
GIK
K
V
V
A
EIM
P
E
D
K
S
R
I
V
S
E
L
K
D
K
GLI
V
A
M
A
G
D
G
VND
A
P
A
L
A
K
AD
I
G
I
A
M
GTGTD
V
A
I
E
S
A
GVTLLHGDLRG
I
A
K
A
R
R
L
S
E
S
T
M
S
N
I
R
Q
N
L
F
F
A
F
I
Y
N
V
L
G
V
P
L
A
A
GVLYPLTGLLLS
P
M
I
A
A
A
A
M
A
L
S
S
V
S
V
I
I
N
A
L
R
LKRVTL
16
HHSearch
44.86
9%
-57
- C3 -
1N3Y
-
ITAX_HUMAN
A:
[129-177]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
E
Q
D
I
V
F
L
-
I
D
------
G
S
G
S
-----
I
S
S
R
N
--
F
--------
A
------
T
-----
M
M
N
F
V
R
A
V
I
S
Q
F
Q
--
R
--
P
S
T
Q
F
S
L
M
Q
F
S
N
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
HHSearch
42.05
7%
-48
- C3 -
1MF7
-
ITAM_HUMAN
A:
[132-179]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
S
D
I
A
F
L
-
I
D
------
G
S
G
S
-----
I
I
P
H
D
--
F
--------
R
------
R
-----
M
K
E
F
V
S
T
V
M
E
Q
L
K
--
K
--
S
K
T
L
F
S
L
M
Q
Y
S
E
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
HHSearch
41.58
7%
-42
- C3 -
3N2N
4
ANTR1_HUMAN
F:
[7-54]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
F
D
L
Y
F
I
-
L
D
------
K
S
G
S
-----
V
LH-
H
--
W
--------
N
------
E
-----
I
Y
Y
F
V
E
Q
L
A
H
K
F
I
--
S
--
P
Q
L
R
M
S
F
I
V
F
S
T
R
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
40.74
9%
-14
- C5 -
2XZZ
-
TGM1_HUMAN
A:
[-1-767]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
L
S
L
T
----
L
---
L
G
A
A
V
V
----------------------
G
Q
E
C
E
V
Q
I
V
F
K
N
P
-
L
--
P
V
T
L
T
N
V
V
F
---
R
----
L
E
G
S
G
L
Q
R
P
K
-
I
-
L
N
V
G
D
I
G
G
N
---
E
T
V
T
L
R
Q
S
F
V
P
V
R
P
G
P
R
Q
L
I
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
HHSearch
39.29
13%
-19
- C5 -
1L9M
-
TGM3_HUMAN
A:
[601-671]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
N
E
A
R
V
----------------------
R
K
P
V
N
V
Q
M
L
F
S
N
P
-
L
--
D
E
P
V
R
D
C
V
L
---
M
----
V
E
G
S
-
G
L
L
L
G
N
L
K
I
D
V
P
T
L
G
P
K
---
E
R
S
R
V
R
F
D
I
L
P
S
R
S
G
T
K
Q
L
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
38.74
7%
-28
- C- -
2X31
-
BCHD_RHOCB
A:
[7-155]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
D
R
V
L
I
F
A
-
V
D
------
A
S
G
S
-----
A
AVA---
L
--------
S
------
E
-----
A
K
G
A
V
E
L
L
L
G
R
A
Y
--
A
--
A
R
D
H
V
S
L
I
T
F
R
G
T
A
A
Q
V
L
-
L
Q
P
S
R
S
L
T
Q
T
K
R
Q
L
Q
G
L
P
G
G
G
G
--
T
PL
A
-
S
-
G
---
M
E
M
A
M
VT
A
-----
K
Q
AR
S
----------
R
----------
G
M
T
-
P
T
I
A
L
-
L
T
D
G
R
------------
G
N
I
AL
D
G
T
A
N
R
ELAGEQ
A
-----
T
K
V
A
R
A
I
R
---
A
---
S
G
M
--
P
A
V
I
I
D
T
A
M
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
37.18
4%
-23
- C3 -
1SHU
1
ANTR2_HUMAN
X:
[6-52]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
F
D
L
Y
F
V
-
L
D
------
K
S
G
S
-----
V
---
A
NN
W
--------
I
------
E
-----
I
Y
N
F
V
Q
Q
L
A
E
R
F
V
--
S
--
P
E
M
R
L
S
F
I
V
F
S
S
Q
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
HHSearch
36.93
9%
-32
- C3 -
2IUE
-
A:
[3-51]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
V
D
L
Y
F
L
-
M
G
------
L
S
G
S
-----
A
QG-
H
--
L
--------
S
------
N
-----
V
Q
T
L
G
S
D
L
L
K
A
L
N
--
E
I
S
R
S
G
R
I
G
F
G
S
I
V
N
M
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
35.20
27%
58
- C- -
2RCJ
-
IGHG1_HUMAN
C:
[187-270]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
K
S
H
----
R
S
Y
S
C
Q
V
T
H
E
----------------------
G
S
T
V
E
K
T
V
A
P
T
E
C
-
S
--
A
S
T
K
G
P
S
V
F
---
P
LA--
P
S
S
K
S
T
S
G
G
T
A
A
L
G
C
L
V
K
D
Y
F
P
---
Q
P
V
T
V
S
W
N
S
G
A
L
T
S
G
V
H
T
F
P
A
V
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
35.04
14%
-5
- C5 -
3IDU
1
?
A:
[15-93]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
F
---
P
D
L
T
V
E
----
I
K
-
G
P
D
V
V
G
V
----------------------
N
K
L
A
E
Y
E
V
H
V
K
N
L
-
G
--
G
I
G
V
P
S
T
K
V
---
R
----
V
Y
I
N
G
T
L
Y
K
---
N
W
T
V
-
S
L
G
P
K
---
E
E
K
V
L
T
F
N
W
T
P
T
Q
E
G
M
Y
R
I
N
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------