@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo0695: (2016-03-17 )
MLIPDNLLQPVVGKKQVEPKESLAEELVELPFISLLMENSPAPLIKGEADNEEQATIPLKEIAPSLVSAKLLDSEPETKLPSAPLELKEVKETLAAIAKQAIDQPKIDSAPQVAQPPEMNTPKEPTKNTTREQQPPPELIMPTKDSPKLAENVAKNQPALAKLPQEKEAVQLFKASIKEPVTAKEEVAVKKPAESSNIWHDTTKQLTPAAKVEVPVTLKQLDKTITDQIEQLQKFQVKQNKAFFAIQPESLGKVEVLLKKMPDKIFVHIEYQEQTAKQKLEQMAQDLHNRFRDRGVEVAVTMTEKQAPKENGQGSEGRHHGESKKEKERENPHQEKAKQQVFDLEEET
Atome Classification :
(20 SA)
------------......--...10------..-.-----...-...20......---------------...--30........40..-....-----.-.50........60--..-----..----....70........--80.....-...90........100....--------...110.......120.------......-------130........140----.-----.------------.....150......-----------.160.----....-..170.......---------180-.........190.--......200.......210------------------.......220-----...--..-....230...-....240----..--------..--...---250-...-..-..260--..----..-------.-..270.-----------.----------..---------...---------------------------280...---......------------------290-..---...----...300.---..------....310........320..------------.....330.-------......340......----------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
------------MLI
P
D
N
--
L
L
Q
P
-------VV-G-----KKQ-VE
P
K
-
E
S
L
A
E
E
---------------
L
V
E--
L
P
F
I
S
L
L
MENSPAP-LIKG-----E-ADNEEQATI
P
L
K
E
--
I
A
-----
P
S
----
L
V
S
A
K
LLDSEPETK--LPSAP
L
E
-
L
K
E
V
K
E
T
L
A
A
I
A
K
QAIDQPK--------IDSAPQVAQPPEMNTPK------EPTKNT-------T-REQQPPP
E
L
IMP----T-----K------------DS
P
K
L
A
E
N
V
AKNQ
P
-----------
A
L
A
KL----P
Q
E
K
-
E
A
V
Q
L
F
K
A
S
IKE---------P---VTAKE
E
V
A
VKKPA--ESSNIWHD
T
T
KQLTPAA
K
V
------------------
E
V
P
V
T
L
K
Q
-------
L
D
K
--
T
I
-
T
D
Q
I
E
Q
L
Q
K
F
-
Q
VKQN
K
A
----
F
F
--------
A
I--QPE---SL
G
-
K
V
E
-
V
L
-
L
K
KMP--
D
K
----
I
F
-------
V
-
H
I
E
Y
Q
E
-----------
Q
----------
T
A
---------
K
Q
K
---------------------------
L
--
E
Q
M
---
A
Q
D
L
H
N
------------------
R
-
F
-
R
D---RG
V
----
E
V
A
V
T
MT---EK------QAPKEN-GQGSEGRHHGES
K
------------
K
E
K
EREN
P
H
-------
Q
E
K
A
K
Q
Q
V
F
DLEEET----------------------------------
29
Fugue
79.70
17%
24
- C4 -
4D10
-
CSN3_HUMAN
C:
[3-403]
--------------
S
A
L
E
--
Q
F
V
N
-------
S
V
-
R
-----
Q
L
S
-
A
Q
G
Q
-
M
T
Q
L
C
E
---------------
L
I
N
--
K
S
G
E
L
L
A
K
N
L
S
H
L
D
-
T
V
L
G
-----
A
-
L
D
V
Q
E
H
S
L
G
V
L
A
V
--
L
F
V
KFSM
P
S
----
V
P
D
F
E
T
L
F
S
Q
V
Q
L
F
--
I
S
T
C
N
G
E
H
I
R
Y
A
T
D
T
F
A
G
L
C
H
Q
L
T
N
A
L
V
E
R
KQP
L
R
G
I
G
I
L
K
Q
A
I
D
K
M
Q
M
N
T
N
Q
LT
S
I
H
A
D
L
C
Q
L
C
-------
L
-
L
A
K
C
F
K
P
A
L
P
Y
L
----
D
-----
V
DM
M
D
I
C
K
E
NGAY
D
A
K
H
F
L
C
Y
Y
Y
Y
G
G
M
-----------
I
Y
T
G
L
----
K
N
F
E
-
R
A
L
Y
F
Y
E
Q
A
I
T
T
---------
P
AMA
V
S
H
I
M
L
E
S
Y
K
K
Y
I
--
L
V
S
L
I
L
L
G
K
V
Q
Q
L
P
K
Y
T
S
Q
------------------
I
V
G
R
F
I
K
P
L
S
N
A
Y
H
E
L
A
Q
--
V
Y
S
T
N
N
P
S
E
L
R
N
L
-
V
N
K
H
S
E
T
----
F
T
--------
R
D
--
N
-----
N
M
G
-
L
V
K
-
Q
C
-
L
S
S
L
Y
--
K
K
----
N
I
Q
R
L
T
K
T
F
L
-
T
L
S
L
Q
D
-----------
M
----------
A
S
---------
R
V
Q
---------------------------
L
SG
P
Q
E
---
A
E
K
Y
V
L
------------------
H
-
M
-
I
E
---
D
G
-----
E
I
F
A
S
I
N
---
Q
K
DG
M
V
S
F
H
D
N
P
E
K
-
Y
N
N
P
A
M
L
H
N
I
D
Q
E
------------
M
L
K
C
I
E
L
D
E
-------
R
L
K
A
M
D
Q
E
I
T
V
N
P
Q
F
----------------------------------
34
Fugue
68.85
14%
31
- C5 -
1Y10
5
Y1264_MYCTU
A:
[14-376]
----------------
D
D
--
L
L
G
D
-------
L
--
G
-----
G
T
A
-
R
A
E
R
-
A
K
L
V
E
W
---------------
L
L
E
Q
G
I
T
P
D
E
I
R
A
T
N
P
P
L
L
-
L
A
T
R
-----
H
-
L
V
G
D
D
G
T
Y
V
S
A
R
E
--
I
S
-----
E
N
Y
GVD
L
E
L
L
Q
R
V
Q
R
A
V
G
L
A
--
R
V
D
D
P
D
A
-
V
V
H
M
R
A
D
G
E
A
A
A
R
A
Q
R
F
V
E
L
--------
G
L
N
P
D
Q
V
V
L
V
V
R
V
L
A
E
G
------
L
S
H
A
A
E
-------
A
-
M
R
Y
T
A
L
E
A
I
M
R
P
GAT
E
L
-----
D
------------
I
A
K
G
S
Q
A
L
V
S
Q
I
V
P
-----------
L
L
G
P
M
----
I
Q
D
M
-
L
F
M
Q
L
R
H
M
M
E
T
E
---------
A
---
V
N
A
G
E
R
A
A
G
K
P
L
P
G
A
R
Q
V
T
V
A
F
A
D
L
V
G
F
T
Q
L
G
E
V
------------------
V
S
A
E
E
L
G
H
-------
L
A
G
--
R
L
-
A
G
L
A
R
D
L
T
A
P
-
P
V
W
F
I
K
T
IGD
A
V
M
--------
L
V
C
P
D
P
A
---
P
L
L
-
D
T
V
-
L
K
-
L
V
E
V
V
--
D
T
DNNF
P
R
-------
L
-
R
A
G
V
A
S
-----------
G
----------
M
A
---------
V
S
R
---------------------------
A
--
G
D
W
FG
S
P
V
N
V
A
S
------------------
R
-
V
-
T
G
---
V
A
R
----
P
G
A
V
L
V
A
---
D
S
------
V
R
E
A
L
G
-
D
A
D
------
G
F
Q
W
------------
S
F
A
G
P
R
R
L
R
-------
G
I
R
G
D
V
R
L
F
R
V
R
R
------------------------------------
28
Fugue
68.31
13%
-47
- C8 -
2RRL
-
A:
[1-169]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
M
A
S
D
D
R
-----------
A
T
G
P
A
----
L
T
P
L
-
V
V
A
A
A
A
T
S
A
K
V
E
---------
V
---
D
S
P
P
A
P
V
T
H
G
A
A
M
--
P
T
L
S
S
A
T
A
Q
P
L
P
V
A
S
A
P
V
L
------------------
S
A
P
L
G
S
H
E
-------
W
Q
Q
--
T
F
-
S
Q
Q
V
M
L
F
T
R
Q
-
G
Q
Q
--
S
A
----
Q
L
--------
R
L
--
H
P
E
---
E
L
G
-
Q
V
H
-
I
S
-
L
K
L
D
D
--
N
Q
----
A
Q
-------
L
-
Q
M
V
S
P
H
-----------
S
----------
H
V
---------
R
A
A
---------------------------
L
--
E
A
A
---
L
P
M
L
R
T
------------------
Q
-
L
-
A
E
---
S
G
I
----
Q
L
G
Q
S
S
I
---
S
S
------
E
S
F
A
G
Q
-
Q
Q
S
S
S
Q
Q
Q
S
S
R
-------------------------------------------------------------------------------
33
Fugue
67.00
19%
65
- C2 -
4NZR
1
Y281_MYCGE
M:
[26-416]
---------------
N
D
G
--
S
Y
Q
S
-------
E
I
-
D
-----
L
S
G
G
A
N
F
R
-
E
K
F
R
N
F
---------------
A
N
E
--
L
---
S
E
A
I
T
N
S
P
K
G
-
L
D
R
P
-----
V
-
P
K
T
E
I
S
G
L
I
K
T
G
D
NF
I
T
-----
P
S
-----
F
K
A
G
Y
Y
D
H
V
A
S
D
G
--
S
L
L
S
Y
Y
Q
-
S
T
E
Y
F
N
N
R
V
L
M
P
I
L
Q
T
T
N
G
T
--------
L
M
A
N
N
R
G
Y
D
D
V
F
R
Q
V
P
S
FSGW--
S
N
T
K
A
T
-------
T
-
V
S
T
S
N
N
-----
L
----
T
-----
Y
------------
D
K
W
T
Y
F
--
A
A
K
G
S
P
-----------
L
Y
D
S
Y
----
P
N
H
F
F
E
D
V
K
T
L
A
I
D
A
K
D
---------
I
---
S
A
L
K
T
T
I
D
S
E
K
P
----
T
Y
L
I
I
R
G
L
S
G
N
G
S
Q
L
N
E
L
------------------
Q
L
P
E
S
V
K
K
-------
V
S
L
YG
D
Y
-
T
G
V
N
V
A
K
Q
I
F
-
A
N
V
V
E
L
E
----
F
Y
STSKANSF
G
F
--
N
P
L
---
V
L
G
S
K
T
N
-
V
I
-
Y
D
L
F
A
--
S
K
----
P
F
-------
T
-
H
I
D
L
T
Q
-----------
V
----------
T
L
QNSDNSAID
A
N
K
---------------------------
L
--
K
Q
A
---
V
G
D
I
Y
N
YRRFERQFQGYFAGGYID
K
-
Y
-
L
V
---
K
N
V
NTNK
D
S
D
D
D
L
V
---
Y
R
------
S
L
K
E
L
N
-
L
H
L
E
E
A
Y
R
E
G
D
N
T
------------
Y
Y
R
V
N
E
N
Y
Y
PGASIYE
N
E
R
A
S
R
D
-
S
E
F
Q
N
E
I
LKR-------------------------------
35
Fugue
62.27
17%
43
- C6 -
5BP8
6
?
A:
[6-520]
A
P
R
E
A
E
A
A
A
L
L
A
A
T
V
A
D
P
WG
L
V
A
P
SV
Y
D
T
A
R
L
V
-
S
LAPWL
D
G
H
-
R
E
R
L
-
G
Y
L
A
K
E
QNQDGSWGAPDGYG
L
V
P
T
--
L
S
A
V
E
A
L
L
T
E
L
A
R
T
-
D
S
G
A
-----
P
-
H
L
S
P
D
D
L
A
A
A
C
A
D
--
G
L
-----
G
A
----
L
R
D
G
L
L
A
G
P
V
P
D
T
I
G
V
E
F
V
A
P
S
L
-
L
A
D
I
N
T
R
L
A
A
L
T
E
Q
A
P
G
K
L
G
--------
A
W
S
G
T
T
L
T
S
P
A
P
D
L
D
G
A
------
L
L
A
G
V
R
-------
E
M
T
E
Q
A
P
L
P
E
K
L
W
H
----
T
LEAVT
R
------------
D
G
T
R
G
A
R
P
H
E
G
A
P
P
HNGSVGCS
P
A
A
T
A
A
W
L
GAAP
D
P
A
A
-
P
G
V
A
Y
L
R
D
V
Q
A
R
F
GGPVPSIT
P
---
I
V
Y
F
E
Q
A
W
V
L
N
S
L
--
A
A
S
G
L
R
Y
E
A
P
A
A
L
L
D
S
L
E
A
G
LTDE
G
I
A
AAPGLPSD
S
D
D
T
A
A
V
L
F
A
-------
L
A
Q
--
H
---
G
R
T
H
R
P
D
S
L
M
H
F
R
R
D
G
Y
----
F
S
--------
C
F
--
G
V
E
RTP
S
T
S
-
T
N
A
-
H
I
-
L
E
A
L
G
--
H
H
----
V
T
-------
V
-
R
P
D
D
A
G
-----------
R
----------
Y
G
---------
A
E
I
R
M
I
S
D
W
L
L
D
N
QLPDG
S
W
M
D
KWHAS
P
Y
Y
A
--
T
A
C
---
C
A
L
A
L
A
------------------
E
-
F
-
G
G
---
P
S
A
----
R
A
A
V
D
R
A
---
A
A
------
W
A
L
A
T
Q
R
A
D
G
S
W
G
R
W
Q
G
T
T
E
E
T
A
Y
M
V
Q
L
L
M
R
T
R
T
P
G
S
P
G
T
V
-------
A
R
S
A
A
R
G
C
D
A
L
L
A
H
D
DPASYPGL
W
H
D
KDIYAP
V
T
V
I
R
A
A
R
L
A
A
L
A
L
G
GA
18
HHSearch
58.72
19%
-59
* C8 *
2RRL
-
A:
[64-146]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
L
G
S
H
E
-------
W
Q
Q
--
T
F
-
S
Q
Q
V
M
L
F
T
R
---
Q
G
Q
Q
S
A
----
Q
L
--------
R
L
--
H
P
E
---
E
L
G
-
Q
V
H
-
I
S
-
L
K
L
D
D
--
N
Q
----
A
Q
-------
L
-
Q
M
V
S
P
H
-----------
S
----------
H
V
---------
R
A
A
---------------------------
L
--
E
A
A
---
L
P
M
L
R
T
------------------
Q
-
L
-
A
E
---
S
G
I
----
Q
L
G
----------------------------------------------------------------------------------------------------------------
32
Fugue
53.22
10%
35
* C6 *
2HQY
1
?
A:
[1-298]
------------
M
I
P
F
K
D
--
I
--
T
-------
L
A
-
D
-----
R
D
T
-
I
T
A
F
T
M
K
S
D
R
R
---------------
N
C
D
--
L
S
F
S
N
L
C
S
--------------------
W
R
F
L
Y
D
T
Q
F
A
V
--
I
D
-----
D
F
----
L
V
F
K
F
W
A
G
E
Q
L
A
Y
M
--
M
P
V
G
N
G
D
-
L
K
A
V
L
R
K
L
I
E
D
A
D
K
E
K
H
N
F
C
--------
M
L
G
V
C
--
S
N
M
R
A
D
L
E
A
I
------
L
P
E
R
F
I
-------
F
-
T
E
D
R
A
Y
A
D
Y
I
Y
L
----
R
-----
S
------------
D
L
A
T
L
K
G
--------------------
K
K
F
----
Q
A
K
R
-
N
H
I
N
R
F
R
N
T
------------------
Y
P
D
Y
E
Y
T
P
I
T
P
--
D
R
I
Q
E
C
L
D
L
E
A
E
W
C
K
V
N
N
C
------------------
D
Q
Q
E
G
T
G
N
-------
E
R
R
--
A
L
-
I
Y
A
L
H
N
F
E
A
L
-
G
L
T
G
G
I
L
----
H
V
--------
N
G
--
K
I
V
---
A
F
T
-
F
G
M
-
P
I
-
N
---
H
--
E
T
----
F
G
-------
V
-
H
V
E
K
A
D
-----------
T
----------
S
I
---------
D
G
A
---------------------------
Y
--
A
M
I
---
N
Y
E
F
A
N
------------------
R
-
I
-
P
E
---
Q
Y
I
----
Y
I
N
------------------
R
E
E
-
D
L
G
I
-----
E
G
L
R
------------
K
A
K
L
S
Y
Q
P
V
-------
T
I
L
E
K
Y
M
A
C
L
K
D
H
------------------------------------
26
HHSearch
46.24
23%
-13
- C7 -
3W4R
-
?
A:
[139-188]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
F
--
D
G
----
L
D
-------
L
-
D
W
E
Y
P
G
-----------
A
ADRGGSF---
S
D
---------
K
D
K
---------------------------
F
--
L
Y
L
---
V
Q
E
L
R
R
------------------
A
-
F
-
I
R
---
E
G
K
----
G
W
E
L
T
A
A
------------------------------------------------------------------------------------------------------------
21
HHSearch
45.24
18%
-21
- C7 -
2YMB
-
MITD1_HUMAN
A:
[146-198]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
C
E
-
M
L
-
I
K
--
C
--
K
V
----
K
T
-------
I
-
H
L
L
T
S
L
-----------
D
----------
E
G
IE-------
Q
V
Q
---------------------------
Q
--
S
R
G
---
L
Q
E
I
E
E
------------------
S
-
L
-
R
S
---
H
G
V
----
L
L
E
V
Q
Y
S
---
S
--------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
44.45
22%
77
- C7 -
1T5C
2
CENPE_HUMAN
A:
[102-217]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
--------
G
V
--
I
P
R
---
A
I
H
-
D
I
F
-
Q
K
-
I
K
K
F
P
--
D
R
----
E
F
-------
L
L
R
V
S
Y
M
E
I
Y
NE
T
I
T
D
LLC
G
----------
T
Q
---------
K
M
K
---------------------------
P
--
L
I
I
---
R
E
D
V
N
R
------------------
N
-
V
-
Y
V
---
A
D
L
----
T
E
E
V
V
Y
T
---
S
E
------
M
A
L
K
W
I
-
T
K
G
E
K
S
R
H
Y
G
E
T
K
------------
M
N
Q
R
S
S
R
S
H
--------------------------------------------------------
37
Fugue
44.14
19%
88
- C1 -
4H3W
-
?
A:
[38-350]
----------------
E
S
--
W
V
A
P
-------
L
G
M
G
-----
Y
V
T
---------
S
D
D
---------------
V
V
N
--
V
E
V
P
S
I
R
E
V
D
G
A
Y
V
M
I
Y
D
G
-----
E
M
I
G
S
L
R
A
A
S
D
V
--
E
--
I
A
-----
S
E
----
D
I
T
T
G
D
I
D
G
L
F
D
G
D
--
F
V
L
A
----
L
T
N
P
H
I
T
L
S
N
V
N
A
S
L
D
C
S
L
S
--------
I
E
A
E
---------
N
T
S
E
------
A
T
S
S
D
F
-------
T
-
L
S
T
V
S
P
N
I
W
I
G
P
----
L
-----
D
--------------
P
T
D
A
F
F
V
N
E
L
P
G
-----------
I
V
Q
I
V
----
P
Q
------------
I
H
L
---------
S
---
L
S
A
D
S
Q
W
T
N
A
P
A
D
--
A
L
S
E
L
R
Y
A
V
E
L
P
L
T
P
A
P
E
F
------------------
S
A
V
S
V
E
R
I
-------
E
D
A
--
F
D
-
E
D
F
V
D
Y
I
--
F
-
S
D
G
S
A
R
I
----
Y
G
--------
E
V
--
T
N
E
M--
P
F
D
M
S
I
E
M
V
I
M
D
---
E
--
N
N
----
V
P
-------
V
-
D
I
Q
F
P
A
-----------
Q
----------
E
V
---------
G
Q
----------------------------
S
--
G
E
V
---
I
F
E
I
T
E
------------------
D
M
P
M
D
A
---
R
H
I
----
D
L
N
L
H
L
T
-----------------------
G
R
D
Q
G
E
A
--------------------------------
L
G
Q
T
T
F
N
L
L
E
G
G
I---------------------------------
20
HHSearch
43.16
9%
-12
* C7 *
3CZ8
1
YDHD_BACSU
A:
[111-153]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
Y
--
G
G
----
V
T
-------
I
-
D
F
E
Q
V
S
-----------
A
----------
A
D
---------
R
D
L
---------------------------
F
--
T
G
F
---
L
R
Q
L
R
D
------------------
R
-
L
-
Q
A
---
G
G
Y
----
V
L
T
I
A
V
P
------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
41.16
28%
45
- C7 -
1GEW
1
HIS8_ECOLI
A:
[192-267]
----------------------------------------------
P
Q
-
A
S
L
A
G
W
---------------
L
A
E
--
Y
P
H
L
A
I
L
R
T
L
S
K
A
F
-
A
L
A
G
LR
C
G
F
T
-
L
A
N
E
E
V
I
N
L
L
M
K
V
--
I
A
-----
P
Y
----
P
L
S
T
P
V
A
D
I
A
A
Q
A
L
--
S
P
Q
G
I
V
A
-
M
R
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
40.37
28%
45
- C7 -
1GEX
2
HIS8_ECOLI
A:
[192-267]
----------------------------------------------
P
Q
-
A
S
L
A
G
W
---------------
L
A
E
--
Y
P
H
L
A
I
L
R
T
L
S
K
A
F
-
A
L
A
G
LR
C
G
F
T
-
L
A
N
E
E
V
I
N
L
L
M
K
V
--
I
A
-----
P
Y
----
P
L
S
T
P
V
A
D
I
A
A
Q
A
L
--
S
P
Q
G
I
V
A
-
M
R
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
40.24
28%
46
- C7 -
1GEY
1
HIS8_ECOLI
A:
[192-267]
----------------------------------------------
P
Q
-
A
S
L
A
G
W
---------------
L
A
E
--
Y
P
H
L
A
I
L
R
T
L
S
K
A
F
-
A
L
A
G
LR
C
G
F
T
-
L
A
N
E
E
V
I
N
L
L
M
K
V
--
I
A
-----
P
Y
----
P
L
S
T
P
V
A
D
I
A
A
Q
A
L
--
S
P
Q
G
I
V
A
-
M
R
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
39.26
28%
45
- C7 -
1IJI
1
HIS8_ECOLI
A:
[192-267]
----------------------------------------------
P
Q
-
A
S
L
A
G
W
---------------
L
A
E
--
Y
P
H
L
A
I
L
R
T
L
S
K
A
F
-
A
L
A
G
LR
C
G
F
T
-
L
A
N
E
E
V
I
N
L
L
M
K
V
--
I
A
-----
P
Y
----
P
L
S
T
P
V
A
D
I
A
A
Q
A
L
--
S
P
Q
G
I
V
A
-
M
R
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
37.94
26%
113
- C7 -
4HL8
-
MVP_RAT
A:
[644-710]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
P
V
D
Q
------------------
R
-
T
-
R
D
A
L
Q
R
S
V
----
Q
L
A
I
E
I
T
T
N
S
Q
E
------
A
A
A
K
H
E
-
A
Q
R
L
E
Q
E
A
R
G
R
L
E
------------
R
Q
K
I
L
D
Q
S
E
-------
A
E
K
A
R
K
E
L
L
E
L
E
-------------------------------------
23
HHSearch
36.98
12%
-8
- C7 -
1EDQ
-
?
A:
[296-349]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
V
K
-
E
F
-
L
Q
T
W
K
FF
D
G
----
V
D
-------
I
-
D
W
E
F
P
G
-----------
G
KGANPNLGSP
Q
D
---------
G
E
T
---------------------------
Y
--
V
L
L
---
M
K
E
L
R
A
------------------
M
-
L
-
D
Q
---
L
-------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
36.35
26%
152
- C7 -
1EE5
1
A:
[4-63]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
Q
M
T
Q
Q
L
N
S
D
D
M
Q
------
E
Q
L
S
A
T
V
K
F
R
Q
I
L
S
-
R
E
H
R
P
P
I
D
V
V
I
Q
----
A
-----
G
------------
V
V
P
R
L
V
E
F
M
R
E
N
Q
P
-----------
E
M
L
Q
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
36.05
26%
109
- C7 -
2QZV
-
MVP_RAT
A:
[644-710]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
P
V
D
Q
------------------
R
-
T
-
R
D
A
L
Q
R
S
V
----
Q
L
A
I
E
I
T
T
N
S
Q
E
------
A
A
A
K
H
E
-
A
Q
R
L
E
Q
E
A
R
G
R
L
E
------------
R
Q
K
I
L
D
Q
S
E
-------
A
E
K
A
R
K
E
L
L
E
L
E
-------------------------------------