@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo0794: (2016-03-18 )
MKIGIIGATGRAGSRILEEAKNRGHEVTAIVRNAGKITQTHKDINILQKDIFDLTLSDLSDQNVVVDAYGVSPDEAEKHVTSLDHLISVLNGTVSPRLLVVGGAASLQIDEDGNTLLESKGLREAPYYPTARAQAKQLEHLRSHQAEFSWTYISPSAMFEPGERTGDYQIGKDHLLFGSDGNSFISMEDYAIAVLDEIERPNHLNERFTVAGK
Atome Classification :
(20 SA)
---.........10........20..--.--.-....30.....--..-.-40.-..-......50--....--.-...60-.........----70-...-------.----------------------...--.80........90...-..---...100.......110-..---.-...-----.120.......130......-.-140.......150.......160---....-..----.--.--170----...--.---.....180---.......190.......200.---.......210.------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---
M
K
I
G
I
I
GATGR
A
G
S
R
I
L
E
E
A
KNR--G--H-
E
V
T
A
I
V
RNAGK--IT-
Q
-
T
-
H
-
K
D
-
I
N
I
L
Q
K
D
I
--
F
D
L
T
--
L
-
S
DLS--DQ
N
V
V
V
D
AY----GV-
S
P
D
-------
E
----------------------
A
E
K
--
H
V
T
S
L
D
H
L
I
S
V
L
NGTV-S
P
---
R
L
L
V
V
GG
A
A
S
L
Q
IDED-G
N
---
T
-
L
L
E-----SKGLREAPYYP
T
A
R
A
Q
A
K
Q
L
-
E
-
H
L
R
S
HQA
E
F
S
W
T
Y
I
S
P
S
AMFEP----GERT-GD----Y--Q--I------GK
D
--
H
---
L
L
FGSDGN---
S
F
I
S
M
E
D
Y
A
I
A
V
L
D
EIERP-N---HLNE
R
F
TVAGK------------------------------------------------------------------------------------------
1
PsiBlast_PDB
88.93
97%
-97
- C1 -
3EW7
-
?
A:
[2-212]
----
K
I
G
I
I
G
A
T
G
R
A
G
S
R
I
L
E
E
A
K
N
R
--
G
--
H
-
E
V
T
A
I
V
R
N
A
G
K
--
I
T
-
Q
-
T
-
H
-
K
D
-
I
N
I
L
Q
K
D
I
--
F
D
L
T
--
L
-
S
D
L
S
--
D
Q
N
V
V
V
D
A
Y
----
G
I
-
S
P
D
-------
E
----------------------
A
E
K
--
H
V
T
S
L
D
H
L
I
S
V
L
N
G
T
V
-
S
P
---
R
L
L
V
V
G
G
A
A
-----------------------------
A
P
Y
Y
P
T
A
R
A
Q
A
K
Q
L
-
E
-
H
L
K
S
H
Q
A
E
F
S
W
T
Y
I
S
P
S
A
M
F
E
P
----
G
--------------------------------------------
F
I
S
M
E
D
Y
A
I
A
V
L
D
E
I
E
R
P
-
N
---
H
L
N
E
H
F
T
V
A
G
-------------------------------------------------------------------------------------------
2
PsiBlast_PDB
78.99
42%
-74
- C1 -
4R01
3
?
A:
[2-210]
---
M
K
L
A
V
I
A
A
N
G
Q
A
G
K
A
I
V
E
E
A
V
K
R
--
G
--
H
-
E
V
T
A
I
V
R
S
E
N
K
---
S
-
Q
-
A
-
E
-----
S
I
I
K
K
D
L
--
F
E
L
T
--
K
-
D
D
L
T
--
G
F
D
A
V
I
S
A
F
----
G
A
Y
T
P
D
-------
T
----------------------
L
P
L
--
H
S
K
S
I
E
L
F
N
Q
L
L
A
G
T
Q
-
T
----
R
F
L
V
V
G
G
A
G
S
L
Y
I
D
E
T
-
K
T
---
T
R
L
L
D
-----
T
P
D
F
P
E
E
-
F
K
P
L
A
K
A
Q
A
D
E
L
-
D
-
L
L
R
T
K
N
-
N
L
N
W
T
F
V
S
P
A
V
D
F
I
P
D---
G
E
K
T
-
G
N
----
Y
--
I
--
L
------
A
G
E
--
I
---
F
T
T
N
E
K
G
I
---
S
Q
I
S
Y
A
D
Y
A
I
G
L
V
D
E
L
E
K
G
-
H
---
H
I
K
E
R
I
S
L
L
E
K
------------------------------------------------------------------------------------------
21
PsiBlast_CBE
78.98
42%
-72
- C1 -
4R01
4
?
B:
[2-210]
---
M
K
L
A
V
I
A
A
N
G
Q
A
G
K
A
I
V
E
E
A
V
K
R
--
G
--
H
-
E
V
T
A
I
V
R
S
E
N
K
---
S
-
Q
-
A
-
E
-----
S
I
I
K
K
D
L
--
F
E
L
T
--
K
-
D
D
L
T
--
G
F
D
A
V
I
S
A
F
----
G
A
Y
T
P
D
-------
T
----------------------
L
P
L
--
H
S
K
S
I
E
L
F
N
Q
L
L
A
G
T
Q
-
T
----
R
F
L
V
V
G
G
A
G
S
L
Y
I
D
E
T
-
K
T
---
T
R
L
L
D
-----
T
P
D
F
P
E
E
-
F
K
P
L
A
K
A
Q
A
D
E
L
-
D
-
L
L
R
T
K
N
-
N
L
N
W
T
F
V
S
P
A
V
D
F
I
P
D---
G
E
K
T
-
G
N
----
Y
--
I
--
L
------
A
G
E
--
I
---
F
T
T
N
E
K
G
I
---
S
Q
I
S
Y
A
D
Y
A
I
G
L
V
D
E
L
E
K
G
-
H
---
H
I
K
E
R
I
S
L
L
E
K
------------------------------------------------------------------------------------------
4
PsiBlast_PDB
77.62
38%
-81
- C1 -
4JGB
3
?
A:
[6-212]
---
L
K
I
A
L
F
G
A
T
G
M
I
G
S
R
I
A
A
E
A
A
R
R
--
G
--
H
-
Q
V
T
A
L
S
R
N
P
-----------
G
-
A
N
-
V
Q
A
K
A
A
D
L
--
F
D
P
A
S
I
A
-
A
A
L
A
--
G
Q
D
V
V
A
S
A
Y
----
G
P
-
K
Q
E
-------
E
----------------------
A
S
K
--
V
V
A
V
A
K
A
L
V
D
G
A
R
K
A
G
-
V
K
---
R
V
V
V
V
G
G
A
G
T
L
E
V
-
A
P
-
G
K
---
Q
-
L
V
D
-----
T
E
G
F
P
D
A
-
Y
K
A
V
A
L
A
H
R
D
A
Y
-
G
-
Y
L
S
T
V
Q
-
D
L
D
W
T
F
F
S
P
A
A
L
I
A
P
----
G
E
R
T
-
G
R
----
F
--
R
--
T
------
G
A
G
--
R
---
L
I
V
D
E
Q
G
N
---
S
K
I
S
A
E
D
Y
A
I
A
F
V
D
E
I
E
Q
G
-
R
---
F
I
R
Q
A
A
T
A
A
--------------------------------------------------------------------------------------------
22
PsiBlast_CBE
77.48
38%
-77
- C1 -
4JGB
2
?
B:
[6-212]
---
L
K
I
A
L
F
G
A
T
G
M
I
G
S
R
I
A
A
E
A
A
R
R
--
G
--
H
-
Q
V
T
A
L
S
R
N
P
-------------
A
N
-
V
Q
A
K
A
A
D
L
--
F
D
P
A
S
I
A
-
A
A
L
A
--
G
Q
D
V
V
A
S
A
Y
----
G
P
-
K
Q
E
-------
E
----------------------
A
S
K
--
V
V
A
V
A
K
A
L
V
D
G
A
R
K
A
G
-
V
K
---
R
V
V
V
V
G
G
A
G
T
L
E
V
-
A
P
-
G
K
---
Q
-
L
V
D
-----
T
E
G
F
P
D
A
-
Y
K
A
V
A
L
A
H
R
D
A
Y
-
G
-
Y
L
S
T
V
Q
-
D
L
D
W
T
F
F
S
P
A
A
L
I
A
P
----
G
E
R
T
-
G
R
----
F
--
R
--
T
------
G
A
G
--
R
---
L
I
V
D
E
Q
G
N
---
S
K
I
S
A
E
D
Y
A
I
A
F
V
D
E
I
E
Q
G
-
R
---
F
I
R
Q
A
A
T
A
A
--------------------------------------------------------------------------------------------
5
PsiBlast_PDB
76.53
35%
-74
- C1 -
3H2S
1
?
A:
[2-212]
----
K
I
A
V
L
G
A
T
G
R
A
G
S
A
I
V
A
E
A
R
R
R
--
G
--
H
-
E
V
L
A
V
V
R
D
P
Q
K
--
A
A
D
R
-
L
-
G
-
A
T
-
V
A
T
L
V
K
E
P
--
L
V
L
T
--
E
-
A
D
L
D
--
S
V
D
A
V
V
D
A
L
----
S
V
-
P
W
G
-------
S
----------------------
G
R
G
Y
L
H
L
D
F
A
T
H
L
V
S
L
L
R
N
S
D
-
T
L
---
A
V
F
I
L
G
S
A
S
L
A
M
P
G
A
D
-
H
P
---
M
-
I
L
D
F----
P
E
S
A
A
S
Q
P
W
Y
D
G
A
L
Y
Q
Y
Y
E
Y
-
Q
-
F
L
Q
M
N
-
A
N
V
N
W
I
G
I
S
P
S
E
A
F
P
S
----
G
P
A
T
-
S
-----
Y
--
V
--
A
------
G
K
D
--
T
---
L
L
V
G
E
D
G
Q
---
S
H
I
T
T
G
N
M
A
L
A
I
L
D
Q
L
E
H
P
-
T
---
A
I
R
D
R
I
V
V
---------------------------------------------------------------------------------------------
59
HHSearch
67.84
32%
-62
- C1 -
3H2S
1
?
A:
[1-214]
---
M
K
I
A
V
L
G
A
T
G
R
A
G
S
A
I
V
A
E
A
R
R
R
--
G
--
H
-
E
V
L
A
V
V
R
D
P
Q
K
--
A
A
-
D
---
R
-
L
G
-
A
T
V
A
T
L
-
V
--
K
E
P
L
VL
T
E
A
D
L
D
--
S
V
D
A
V
V
D
A
L
----
S
V
-
P
W
G
-------
S
GR--------------------
G
Y
L
--
H
L
D
F
A
T
H
L
V
S
L
L
R
N
S
D
T
L
A
---
V
F
I
L
G
S
A
S
L
A
M
P
G
A
D
--
H
P
MIL
D
-
F
P
E
-----
S
A
A
S
Q
P
W
Y
D
G
A
L
Y
Q
Y
Y
--
E
Y
-
Q
-
F
L
Q
M
N
-
A
N
V
N
W
I
G
I
S
P
S
E
A
F
P
S
----
G
P
A
T
--
S
----
Y
--
V
--
A
------
G
K
D
--
T
---
L
L
V
G
E
D
G
Q
---
S
H
I
T
T
G
N
M
A
L
A
I
L
D
Q
L
E
H
P
-
T
---
A
I
R
D
R
I
V
V
R
D
-------------------------------------------------------------------------------------------
56
HHSearch
65.37
99%
7
- C1 -
3EW7
-
?
A:
[1-212]
---
M
K
I
G
I
I
G
A
T
G
R
A
G
S
R
I
L
E
E
A
K
N
R
--
G
--
H
-
E
V
T
A
I
V
R
N
A
G
K
--
I
T
-
Q
-
T
-
H
-
K
D
-
I
N
I
L
Q
K
D
I
--
F
D
L
T
--
L
-
S
D
L
S
--
D
Q
N
V
V
V
D
A
Y
----
G
I
-
S
P
D
-------
E
----------------------
A
E
K
--
H
V
T
S
L
D
H
L
I
S
V
L
N
G
T
V
-
S
P
---
R
L
L
V
V
G
G
A
A
-----------------------------
A
P
Y
Y
P
T
A
R
A
Q
A
K
Q
L
-
E
-
H
L
K
S
H
Q
A
E
F
S
W
T
Y
I
S
P
S
A
M
F
E
P
----
G
--------------------------------------------
F
I
S
M
E
D
Y
A
I
A
V
L
D
E
I
E
R
P
-
N
---
H
L
N
E
H
F
T
V
A
G
-------------------------------------------------------------------------------------------
63
HHSearch
63.25
36%
-34
- C1 -
3DHN
-
?
A:
[5-219]
---
K
K
I
V
L
I
G
A
S
G
F
V
G
S
A
L
L
N
E
A
L
N
R
--
G
--
F
-
E
V
T
A
V
V
R
H
P
E
K
--
I
K
-
I
-
E
-
N
-
E
H
-
L
K
V
K
K
A
D
V
--
S
S
L
D
E
V
C
-
E
V
C
K
--
G
A
D
A
V
I
S
A
F
----
N
P
------------I---------------------
Y
D
E
--
T
I
K
V
Y
L
T
I
I
D
G
V
K
K
A
G
-
V
N
---
R
F
L
M
V
G
G
A
G
S
L
F
I
A
P
--
G
L
---
R
-
L
M
D
-----
S
G
E
-
V
P
E
N
I
L
P
G
V
K
A
L
G
E
F
Y
L
N
-
F
L
M
K
E
-
K
E
I
D
W
V
F
F
S
P
A
A
D
M
R
P
----
G
V
R
T
-
G
R
----
Y
--
R
--
L
------
G
K
D
--
D
---
M
I
V
D
I
V
G
N
---
S
H
I
S
V
E
D
Y
A
A
A
M
I
D
E
L
E
H
P
-
K
---
H
H
Q
E
R
F
T
I
G
Y
-------------------------------------------------------------------------------------------
58
HHSearch
63.20
19%
-88
- C1 -
3E48
2
?
A:
[1-199]
---
M
N
I
M
L
T
G
A
T
G
H
L
G
T
H
I
T
N
Q
A
I
A
N
--
H
--
I
D
H
F
H
I
G
V
R
N
V
E
K
--
V
P
-
D
D
W
-
R
-
G
K
-
V
S
V
R
Q
L
D
Y
--
F
N
Q
E
S
M
V
-
E
A
F
K
--
G
M
D
T
V
V
F
I
P
----
S
I
-
I
H
P
-------
S
-----------------------
F
K
--
R
I
P
E
V
E
N
L
V
Y
A
A
K
Q
S
G
-
V
A
---
H
I
I
F
I
G
Y
Y
A
D
Q
H
N
N
P
---------------------
F
H
M
S
P
Y
--
F
G
-
Y
--
A
S
-
R
-
L
L
S
T
--
S
G
I
D
Y
T
Y
V
R
M
A
M
Y
M
D
P
----
L
K
P
Y
-
L
P
----
E
--
L
--
M
------
N
M
H
K
L
I
---
Y
P
A
G
D
G
R
I
---
N
Y
I
T
R
N
D
I
A
R
G
V
I
A
I
I
K
N
P
-
D
---
T
W
G
K
R
Y
L
L
S
G
-------------------------------------------------------------------------------------------
73
HHSearch
63.11
14%
-106
- C1 -
3QVO
1
?
A:
[24-223]
---
K
N
V
L
I
L
G
A
G
G
Q
I
A
R
H
V
I
N
Q
L
A
D
K
--
Q
T-
I
-
K
Q
T
L
F
A
R
Q
P
A
K
--
I
H
-
K
-
P
Y
P
-
T
N
-
S
Q
I
I
M
G
D
V
--
L
N
H
A
A
L
K
-
Q
A
M
Q
--
G
Q
D
I
V
Y
A
N
L
----
T
G
-
E
D
------------------------------------
L
D
I
Q
A
N
S
V
I
A
A
M
K
A
C
D
-
V
K
---
R
L
I
F
V
L
S
L
G
----------------------------
I
G
E
P
L
K
---
P
F
R
R
A
A
-
D
-
A
I
E
A
--
S
G
L
E
Y
T
I
L
R
P
A
W
L
T
D
E
----
D
I
I
---
D
----
Y
--
E
--
L
------
T
--------
S
R
N
E
P
F
K
G
---
T
I
V
S
R
K
S
V
A
A
L
I
T
D
I
I
D
K
P
E
K
---
H
I
G
E
N
I
G
I
N
Q
-------------------------------------------------------------------------------------------
66
HHSearch
62.45
21%
-81
- C1 -
3E8X
2
?
A:
[22-222]
---
M
R
V
L
V
V
G
A
N
G
K
V
A
R
Y
L
L
S
E
L
K
N
K
--
G
--
H
-
E
P
V
A
M
V
R
N
E
E
Q
--
G
P
-
E
-
L
-
R
E
R
G
A
S
D
I
V
V
A
N
L
--
E
E
-
D
F-
S
-
H
A
F
A
--
S
I
D
A
V
V
F
A
A
----
G
S
-
G
P
H
-------
T
G
A
D
K
T
-----------------
I
L
I
--
D
L
W
G
A
I
K
T
I
Q
E
A
E
K
R
G
-
I
K
---
R
F
I
M
V
S
S
V
G
T
V
D
P
D
Q
--
G
----------------
P
-
M
N
M
R
H
Y
L
V
A
K
R
L
A
--
D
-
D
-
E
L
K
R
--
S
S
L
D
Y
T
I
V
R
P
G
P
L
S
N
E
----
E
S
-
T
-
G
K
----
V
--
T
--
V
------
S
---------
P
H
F
S
E
I
T
---
R
S
I
T
R
H
D
V
A
K
V
I
A
E
L
V
D
Q
Q
-
H
---
T
I
G
K
T
F
E
V
L
N
-------------------------------------------------------------------------------------------
55
HHSearch
61.79
17%
-66
* C1 *
1XQ6
1
Y5224_ARATH
A:
[5-230]
---
P
T
V
L
V
T
G
A
S
G
R
T
G
Q
I
V
Y
K
K
L
K
E
G
--
S
DK
F
-
V
A
K
G
L
V
R
S
A
Q
G
--
K
E
-
K
-
I
-
G
-
G
E
-
A
D
V
F
I
G
D
I
--
T
D
A
D
SI
N
-
P
A
F
Q
--
G
I
D
A
L
V
I
L
T
----
S
A
-
V
P
K
-------
M
KPGFDPTKGG
R
P
E
F
I
F
E
DGQYP
E
Q
V
--
D
W
I
G
Q
K
N
Q
I
D
A
A
K
V
A
G
-
V
K
---
H
I
V
V
V
G
S
M
G
G
T
N
P
D
H
-------
P
-
L
N
K
---------
L
G
N
G
N
I
--
L
V
W
K
R
K
A
E
-
Q
-
Y
L
A
D
--
S
G
T
P
Y
T
I
I
R
A
G
G
L
L
D
K
----
E
G
G
V
-
R
E
----
L
--
L
--
V
------
G
K
D
D-
E
---
L
L
--
Q
T
D
T
---
K
T
V
P
R
A
D
V
A
E
V
C
I
Q
A
L
L
F
E
-
E
---
A
K
N
K
A
F
D
L
G
S
-------------------------------------------------------------------------------------------
3
PsiBlast_PDB
61.69
34%
-29
- C1 -
3DHN
-
?
A:
[6-218]
----
K
I
V
L
I
G
A
S
G
F
V
G
S
A
L
L
N
E
A
L
N
R
--
G
--
F
-
E
V
T
A
V
V
R
H
P
E
K
--
I
K
-
I
-
E
-
N
-
E
H
-
L
K
V
K
K
A
D
V
SS
L
D
E
V
--
C
-
E
V
C
K
--
G
A
D
A
V
I
S
A
F
----
N
P
------------------------------------
I
--
Y
D
E
T
I
K
V
Y
L
T
I
I
D
G
V
K
-
K
A
GVN
R
F
L
M
V
G
G
A
G
S
L
F
I
-
A
P
-
G
L
---
R
-
L
M
D
-----
S
G
E
V
P
E
N
-
I
L
P
G
V
K
A
L
G
E
F
Y
-
L
-
N
F
L
M
K
E
K
E
I
D
W
V
F
F
S
P
A
A
D
M
R
P
----
G
V
R
T
-
G
R
----
Y
--
R
--
L
------
G
K
D
--
D
---
M
I
V
D
I
V
G
N
---
S
H
I
S
V
E
D
Y
A
A
A
M
I
D
E
L
E
H
P
-
K
---
H
H
Q
E
R
F
T
I
G
--------------------------------------------------------------------------------------------
64
HHSearch
59.93
16%
-65
- C1 -
2PK3
2
RMD_ANETH
A:
[13-250]
---
M
R
A
L
I
T
G
V
A
G
F
V
G
K
Y
L
A
N
H
L
T
E
Q
--
N
--
V
-
E
V
F
G
T
S
R
N
N
E
A
--
K
------
L
-
P
N
-
V
E
M
I
S
L
D
I
--
M
D
S
Q
R
V
K
-
K
V
I
S
D
I
K
P
D
Y
I
F
H
L
A
----
A
K
-
S
S
V
K
D
S
W
L
N
K
K
G
T
--------------------
F
S
T
--
N
V
F
G
T
L
H
V
L
D
A
V
R
D
S
N
L
D
C
---
R
I
L
T
I
G
S
S
E
E
Y
G
M
I
L
P
E
E
S
---
P
-
V
S
E
-----
E
N
Q
L
R
P
M
S
P
Y
G
V
S
K
A
S
V
G
M
L
A
R
Q
Y
V
K
A
--
Y
G
M
D
I
I
H
T
R
T
F
N
H
I
G
P
----
G
Q
S
L
-
G
F
V
T
Q
D
F
--
A
K
Q
I
V
D
I
E
M
E
K
Q
E
--
P
I
I
K
V
G
N
L
E
A
V
R
---
D
F
T
D
V
R
D
I
V
Q
A
Y
W
L
L
S
Q
Y
G
-----
K
T
G
D
V
Y
N
V
C
S
-------------------------------------------------------------------------------------------
82
Fugue
59.27
16%
-73
- C1 -
1QYC
-
?
A:
[2-308]
G
S
R
S
R
I
L
L
I
G
A
T
G
Y
I
G
R
H
V
A
K
A
S
L
D
L
--
G
--
H
-
P
T
F
L
L
V
R
E
S
T
A
SS
N
S
-
E
-
K
-
A
-
Q
L
-
L
E
S
F
K
A
S
G
--
A
N
I
V
--
H
-
G
S
I
D
--
D
H
A
S
L
V
E
A
V
K
N
V
D
V
V
-
I
S
T
-------
V
----------------------
G
S
L
--
Q
I
E
S
Q
V
N
I
I
K
A
I
K
E
V
G
-
T
V
---
K
R
F
F
P
S
E
F
G
N
D
V
--------------------
D
N
V
H
A
V
E
P
A
K
S
V
F
E
V
K
A
K
V
R
-
R
-
A
I
E
A
E
--
G
I
P
Y
T
Y
V
S
S
N
C
F
A
G
Y
FLRS
L
A
Q
A
-
G
L
----
T
--
A
--
P
------
P
R
D
--
K
---
V
V
I
L
G
D
G
N
A
R
V
V
F
V
K
E
E
D
I
G
T
F
T
I
K
A
V
D
D
P
-
R
---
T
L
N
K
T
L
Y
L
R
L
P
ANTLS
L
N
E
L
V
A
L
W
E
K
K
I
D
K
T
L
E
K
A
Y
V
P
E
E
E
V
L
K
L
I
A
D
TPF
P
A
N
I
S
I
A
I
S
H
S
I
FVKGDQTNFEIGPAGVE
A
S
Q
L
Y
PDVKYTT
V
D
E
Y
L
S
N
F
V
60
HHSearch
58.13
17%
-66
- C1 -
2X4G
-
?
A:
[13-258]
---
V
K
Y
A
V
L
G
A
T
G
L
L
G
H
H
A
A
R
A
I
R
A
A
--
G
--
H
-
D
L
V
L
I
H
R
P
S
S
Q
--
I
Q
-
R
-
L
A
Y
-
L
E
-
P
E
C
R
V
A
E
M
--
L
D
H
A
G
L
E
-
R
A
L
R
--
G
L
D
G
V
I
F
S
-------------------E
E
--------------------
V
A
S
--
A
L
G
Q
T
N
P
F
Y
A
A
C
L
Q
A
R
-
V
P
---
R
I
L
Y
V
G
S
A
Y
A
M
P
R
H
P
Q
-
G
L
---
P
-
G
H
E
GLFYD
S
L
P
-
S
G
K
S
S
Y
V
L
C
K
W
A
L
D
E
Q
A
R
-
E
Q
A
R
--
N
G
L
P
V
V
I
G
I
P
G
M
V
L
G
E
----
L
D
I
G
P
T
T
----
G
--
R
--
V
I
T
A
I
--
G
N
G
--
E
M--
T
H
Y
V
A
G
Q
R
---
N
V
I
D
A
A
E
A
G
R
G
L
L
M
A
L
E
R
G
-----
R
I
G
E
R
Y
L
L
T
G
-------------------------------------------------------------------------------------------
61
HHSearch
57.47
18%
-87
- C1 -
2ZCU
-
QOR2_ECOLI
A:
[1-196]
----
M
I
A
I
T
G
A
T
G
Q
L
G
H
Y
V
I
E
S
L
M
K
T
VP
A
--
S
-
Q
I
V
A
I
V
R
N
P
A
K
--
A
Q
-
A
-
L
A
A
-
Q
G
-
I
T
V
R
Q
A
D
Y
--
G
D
E
A
A
L
T
-
S
A
L
Q
--
G
V
E
K
L
L
L
I
S
-----------------------------------------------
P
Q
H
R
N
V
I
N
A
A
K
A
A
G
-
V
K
---
F
I
A
Y
T
S
L
L
H
A
D
T
S
------------------------
P
L
G
---
L
A
D
E
H
I
E
T
E
-
K
-
M
L
A
D
--
S
G
I
V
Y
T
L
L
R
N
G
W
Y
S
E
N
----
Y
L
A
S
-
A
P
----
A
--
A
--
L
------
E
H
G
V
-
F
I
--
G
A
A
G
D
G
K
I
---
A
S
A
T
R
A
D
Y
A
A
A
A
A
R
V
I
S
E
A
-
G
---
H
E
G
K
V
Y
E
L
A
G
-------------------------------------------------------------------------------------------
71
HHSearch
56.13
14%
-61
- C1 -
3KO8
2
?
A:
[1-244]
---
M
R
I
V
V
T
G
G
A
G
F
I
G
S
H
L
V
D
K
L
V
E
L
--
G
--
Y
-
E
V
V
V
V
D
N
L
S
S
G
--
R
R
-
E
-
F
V
N
-
P
S
-
A
E
L
H
V
R
D
L
--
K
D
Y
S
W-
G
-
A
G
-
I
--
K
G
D
V
V
F
H
F
A
----
A
N
-
P
E
V
-------
R
LSTTE
P
I
V
H
-------------
F
N
E
--
N
V
V
A
T
F
N
V
L
E
W
A
R
Q
T
G
-
V
R
---
T
V
V
F
A
S
S
S
T
V
Y
G
D
A
D
--
V
I
---
P
-
T
P
E
-----
E
E
P
Y
K
P
I
S
V
Y
G
A
A
K
A
A
G
E
V
M
C
A
-
T
Y
A
R
L
-
F
G
V
R
C
L
A
V
R
Y
A
N
V
V
G
P
----
R
L
R
H
-
G
V
----
I
Y
D
F
--
I
M
K
L
R
--
R
N
P
N-
V
L
E
V
L
----
Q
R
K
---
S
Y
L
Y
V
R
D
A
V
E
A
T
L
A
A
W
K
K
F
-
E
E
M
D
A
P
F
L
A
L
N
V
G
N
-------------------------------------------------------------------------------------------
62
HHSearch
55.59
13%
-71
- C1 -
2JL1
6
?
A:
[1-200]
---
F
S
I
A
V
T
G
A
T
G
Q
L
G
G
L
V
I
Q
H
L
L
K
K
VP
A
--
S
-
Q
I
I
A
I
V
R
N
V
E
K
--
A
S
-
T
-
L
A
D
-
Q
G
-
V
E
V
R
H
G
D
Y
--
N
Q
P
E
S
L
Q
-
K
A
F
A
--
G
V
S
K
L
L
F
I
S
----
G
P
-
H
Y
D
------------------------------
N
T
L
--
L
I
V
Q
H
A
N
V
V
K
A
A
R
D
A
G
-
V
K
---
H
I
A
Y
T
G
Y
A
F
A
E
E
--
S
-------------------
I
-
I
P
---
L
A
--
H
V
H
L
A
T
E
-
Y
-
A
I
R
T
--
T
N
I
P
Y
T
F
L
R
N
A
L
Y
T
D
F
----
F
V
N
--
E
G
----
L
--
R
A
-
S
T
-----
E
S
G
--
A
I
V
-
T
N
A
G
S
G
I
V
---
N
S
V
T
R
N
E
L
A
L
A
A
A
T
V
L
T
E
E
-
G
---
H
E
N
K
T
Y
N
L
V
S
-------------------------------------------------------------------------------------------