@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo0816: (2016-03-18 )
MIKLCTISDSQALLEVSYKTFDETFRAQNKPENMDAYLKTNFTAKKLSDELKNPHSYFYFVFHQEAIAGYLKLNIGDAQTEEIAGNTIEIERIYVLKSFQKKGLGKELFNQAIEIAKEVDAKKIWLGVWEKNKNAIQFYAKLGFIKNGQHDFFMGDDCQTDIIMIKDL
Atome Classification :
(20 SA)
----------------------------------------------------------------------------------------------------------------------------------------------------.........10....-....20...-...-----.------.---30........40........50...---..----...60..-...--...70........80------------------------........90........100.......110.......120-...-.....130.......140.......150.---.---.....160......-----
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----------------------------------------------------------------------------------------------------------------------------------------------------
M
I
K
L
C
TISDS
Q
A
L
L
E
-
V
S
Y
K
T
F
D
E
T
-
F
RA-----Q------N---KPE
N
M
D
A
Y
L
KTNF
T
A
K
K
L
S
D
E
LKNP---H
S
----
Y
F
Y
F
V
F
H
-
Q
E
A--I
A
G
Y
L
K
L
NIGDA
Q
T
E
------------------------EIAG
N
T
I
E
I
E
R
I
Y
V
L
K
S
F
Q
K
KGL
G
K
E
L
F
N
Q
A
I
E
I
A
K
EVD-A-K
K
I
-
W
L
G
V
WEKNK
N
A
I
Q
F
Y
AKLGFIKNGQHDFF---M---GDDCQT
D
I
I
M
I
KDL-----
63
HHSearch
96.61
54%
-114
* C2 *
1TIQ
4
PAIA_BACSU
A:
[4-170]
----------------------------------------------------------------------------------------------------------------------------------------------------
K
M
K
K
C
S
R
E
D
L
Q
T
L
Q
Q
-
L
S
I
E
T
F
N
D
T
-
F
K
E
-----
Q
------
N
---
S
P
E
N
M
K
A
Y
L
E
S
A
F
N
T
E
Q
L
E
K
E
L
S
N
M
---
S
S
----
Q
F
F
F
I
Y
F
-
D
H
E
--
I
A
G
Y
V
K
V
N
I
D
D
A
Q
S
E
------------------------
E
M
G
A
E
S
L
E
I
E
R
I
Y
I
K
N
S
F
Q
K
H
G
L
G
K
H
L
L
N
K
A
I
E
I
A
L
E
R
N
-
K
-
K
N
I
-
W
L
G
V
W
E
K
N
E
N
A
I
A
F
Y
K
K
M
G
F
V
Q
T
G
A
H
S
F
Y
---
M
---
G
D
E
E
Q
T
D
L
I
M
A
K
T
------
1
PsiBlast_PDB
95.75
53%
-110
- C2 -
1TIQ
4
PAIA_BACSU
A:
[6-171]
------------------------------------------------------------------------------------------------------------------------------------------------------
K
K
C
S
R
E
D
L
Q
T
L
Q
Q
-
L
S
I
E
T
F
N
D
T
-
F
K
E
-----
Q
------
N
---
S
P
E
N
M
K
A
Y
L
E
S
A
F
N
T
E
Q
L
E
K
E
L
S
N
M
---
S
S
----
Q
F
F
F
I
Y
F
-
D
H
E
--
I
A
G
Y
V
K
V
N
I
D
D
A
Q
S
E
------------------------
E
M
G
A
E
S
L
E
I
E
R
I
Y
I
K
N
S
F
Q
K
H
G
L
G
K
H
L
L
N
K
A
I
E
I
A
L
E
R
N
-
K
-
K
N
I
-
W
L
G
V
W
E
K
N
E
N
A
I
A
F
Y
K
K
M
G
F
V
Q
T
G
A
H
S
F
Y
---
M
---
G
D
E
E
Q
T
D
L
I
M
A
K
T
L
-----
2
PsiBlast_PDB
80.42
39%
-108
* C1 *
4E2A
-
?
A:
[46-206]
------------------------------------------------------------------------------------------------------------------------------------------------------------
D
E
L
S
L
L
Q
K
I
A
I
Q
T
F
R
E
T
-
F
A
F
-----
D
------
N
---
T
A
E
Q
L
Q
N
F
F
D
E
A
Y
T
L
S
V
L
K
L
E
L
D
D
K
---
E
S
----
E
T
Y
F
I
L
M
-
S
G
K
--
A
A
G
F
L
K
V
N
W
G
S
S
Q
T
E
------------------------
Q
V
L
E
D
A
F
E
I
Q
R
L
Y
I
L
K
A
Y
Q
G
L
G
L
G
K
Q
L
F
E
F
A
L
E
R
A
Q
I
S
G
-
L
-
S
W
V
-
W
L
G
V
W
E
K
N
V
K
A
Q
L
L
Y
A
K
Y
G
F
E
Q
F
S
K
H
S
F
F
---
V
---
G
N
K
V
D
T
D
W
L
L
K
K
S
L
-----
4
PsiBlast_PDB
72.99
24%
-85
- C2 -
1WK4
1
?
A:
[3-169]
-----------------------------------------------------------------------------------------------------------------------------------------------------
I
R
R
A
G
L
E
D
L
P
G
V
A
R
-
V
L
V
D
T
W
R
A
T
-
Y
R
G
-----
V
------
V
----
P
E
A
F
L
E
G
L
S
Y
E
G
Q
A
E
R
W
A
Q
R
L
K
T
P
T--
W
P
----
G
R
L
F
V
A
E
-
S
E
S
GE
V
V
G
F
A
A
F
--
G
P
D
R
A
S
------------------------
G
F
P
G
Y
T
A
E
L
W
A
I
Y
V
L
P
T
W
Q
R
K
G
L
G
R
A
L
F
H
E
G
A
R
L
L
Q
A
E
G
-
Y
-
G
R
M
-
L
V
W
V
L
K
E
N
P
K
G
R
G
F
Y
E
H
L
G
G
V
L
L
G
E
R
E
I
E
---
L
---
G
G
A
K
L
W
E
V
A
Y
G
F
D
L
-----
69
HHSearch
72.16
16%
-116
- C2 -
1GHE
1
TTR_PSEAJ
A:
[5-173]
----------------------------------------------------------------------------------------------------------------------------------------------------
Q
L
R
R
V
T
A
E
S
F
A
H
Y
R
H
-
G
L
A
Q
L
L
F
E
T
-
V
H
G
GASVG
F
MAD---
L
---
D
M
Q
Q
A
Y
A
W
C
D
------
G
L
K
A
D
I
A
A
G
---
S
L
----
L
L
W
V
V
A
E
-
D
D
N
--
V
L
A
S
A
Q
L
S
L
C
Q
K
P
N
---------------------------
G
L
N
R
A
E
V
Q
K
L
M
V
L
P
S
A
R
G
R
G
L
G
R
Q
L
M
D
E
V
E
Q
V
A
V
K
H
K
-
R
-
G
L
L
-
H
L
D
T
E
-
A
G
S
V
A
E
A
F
Y
S
A
L
A
Y
T
R
V
G
E
L
P
G
Y
---
C
ATP
D
G
R
L
H
P
T
A
I
Y
F
K
T
L
-----
5
PsiBlast_PDB
72.05
24%
-86
- C2 -
2CY2
1
?
A:
[3-169]
-----------------------------------------------------------------------------------------------------------------------------------------------------
I
R
R
A
G
L
E
D
L
P
G
V
A
R
-
V
L
V
D
T
W
R
A
T
-
Y
R
G
-----
V
------
V
----
P
E
A
F
L
E
G
L
S
Y
E
G
Q
A
E
R
W
A
Q
R
L
K
T
P
T--
W
P
----
G
R
L
F
V
A
E
-
S
E
S
GE
V
V
G
F
A
A
F
--
G
P
D
R
A
S
------------------------
G
F
P
G
Y
T
A
E
L
W
A
I
Y
V
L
P
T
W
Q
R
K
G
L
G
R
A
L
F
H
E
G
A
R
L
L
Q
A
E
G
-
Y
-
G
R
M
-
L
V
W
V
L
K
E
N
P
K
G
R
G
F
Y
E
H
L
G
G
V
L
L
G
E
R
E
I
E
---
L
---
G
G
A
K
L
W
E
V
A
Y
G
F
D
L
-----
6
PsiBlast_PDB
69.13
24%
-123
- C1 -
3FIX
1
PAIA_THEAC
A:
[29-167]
-----------------------------------------------------------------------------------------------------------------------------------------------------
I
R
K
L
S
I
E
D
L
E
T
L
I
E
-
V
A
R
E
S
W
K
W
T
-
Y
A
G
-----
I
------
Y
---
S
E
E
Y
I
E
S
W
I
R
E
K
Y
S
K
E
K
L
L
N
E
I
V
R
S
---
Q
S
NLD
I
L
F
L
G
A
F
A
-
D
S
T
--
L
I
G
F
I
E
L
--------------------------------
K
I
I
A
N
K
A
E
L
L
R
L
Y
L
K
P
E
Y
T
H
K
K
I
G
K
T
L
L
L
E
A
E
K
I
M
K
K
K
G
-
I
-
L
E
C
-
R
L
Y
V
H
R
Q
N
S
V
G
F
S
F
Y
Y
K
N
G
F
-----------------------------------
7
PsiBlast_PDB
68.56
24%
-126
- C1 -
3NE7
7
PAIA_THEAC
A:
[5-143]
-----------------------------------------------------------------------------------------------------------------------------------------------------
I
R
K
L
S
I
E
D
L
E
T
L
I
E
-
V
A
R
E
S
W
K
W
T
-
Y
A
G
-----
I
------
Y
---
S
E
E
Y
I
E
S
W
I
R
E
K
Y
S
K
E
K
L
L
N
E
I
V
R
S
---
Q
S
NLD
I
L
F
L
G
A
F
A
-
D
S
T
--
L
I
G
F
I
E
L
--------------------------------
K
I
I
A
N
K
A
E
L
L
R
L
Y
L
K
P
E
Y
T
H
K
K
I
G
K
T
L
L
L
E
A
E
K
I
M
K
K
K
G
-
I
-
L
E
C
-
R
L
Y
V
H
R
Q
N
S
V
G
F
S
F
Y
Y
K
N
G
F
-----------------------------------
9
PsiBlast_PDB
68.54
24%
-126
- C1 -
3F0A
3
PAIA_THEAC
A:
[8-146]
-----------------------------------------------------------------------------------------------------------------------------------------------------
I
R
K
L
S
I
E
D
L
E
T
L
I
E
-
V
A
R
E
S
W
K
W
T
-
Y
A
G
-----
I
------
Y
---
S
E
E
Y
I
E
S
W
I
R
E
K
Y
S
K
E
K
L
L
N
E
I
V
R
S
---
Q
S
NLD
I
L
F
L
G
A
F
A
-
D
S
T
--
L
I
G
F
I
E
L
--------------------------------
K
I
I
A
N
K
A
E
L
L
R
L
Y
L
K
P
E
Y
T
H
K
K
I
G
K
T
L
L
L
E
A
E
K
I
M
K
K
K
G
-
I
-
L
E
C
-
R
L
Y
V
H
R
Q
N
S
V
G
F
S
F
Y
Y
K
N
G
F
-----------------------------------
8
PsiBlast_PDB
67.81
24%
-134
- C1 -
3K9U
6
PAIA_THEAC
A:
[5-143]
-----------------------------------------------------------------------------------------------------------------------------------------------------
I
R
K
L
S
I
E
D
L
E
T
L
I
E
-
V
A
R
E
S
W
K
W
T
-
Y
A
G
-----
I
------
Y
---
S
E
E
Y
I
E
S
W
I
R
E
K
Y
S
K
E
K
L
L
N
E
I
V
R
S
---
Q
S
NLD
I
L
F
L
G
A
F
A
-
D
S
T
--
L
I
G
F
I
E
L
--------------------------------
K
I
I
A
N
K
A
E
L
L
R
L
Y
L
K
P
E
Y
T
H
K
K
I
G
K
T
L
L
L
E
A
E
K
I
M
K
K
K
G
-
I
-
L
E
C
-
R
L
Y
V
H
R
Q
N
S
V
G
F
S
F
Y
Y
K
N
G
F
-----------------------------------
66
HHSearch
66.82
21%
-86
- C2 -
2CY2
1
?
A:
[2-167]
----------------------------------------------------------------------------------------------------------------------------------------------------
R
I
R
R
A
G
L
E
D
L
P
G
V
A
R
-
V
L
V
D
T
W
R
A
T
-
Y
R
G
-----
V
------
V
---
P
E
A
F
L
E
G
L
-
S
Y
E
G
Q
A
E
R
W
A
Q
R
L
K
T
P
TW-
P
G
----
R
L
F
V
A
E
S
E
S
G
E
--
V
V
G
F
A
A
F
G
P
D
R
A
S
G
F
--------------------------
P
G
Y
T
A
E
L
W
A
I
Y
V
L
P
T
W
Q
R
K
G
L
G
R
A
L
F
H
E
G
A
R
L
L
Q
A
E
G
-
Y
-
G
R
M
-
L
V
W
V
L
K
E
N
P
K
G
R
G
F
Y
E
H
L
G
G
V
L
L
G
E
R
E
I
E
---
L
---
G
G
A
K
L
W
E
V
A
Y
G
F
-------
64
HHSearch
66.67
19%
-112
- C2 -
2DXQ
5
?
A:
[7-144]
----------------------------------------------------------------------------------------------------------------------------------------------------
S
L
R
A
A
G
P
G
D
L
P
G
L
L
E
-
L
Y
Q
V
L
N
P
S
D
-
P
-------
E
------
L
---
T
T
Q
E
A
G
---------
A
V
F
A
A
M
L
A
Q
P
---
G
L
----
T
I
F
V
A
T
E
-
N
G
K
--
P
V
A
T
A
T
L
L
I
V
P
N
L
T
R
------------------------
A
-
A
R
P
Y
A
F
I
E
N
V
V
T
L
E
A
R
R
G
R
G
Y
G
R
T
V
V
R
H
A
I
E
T
A
F
G
A
N
-
C
-
Y
K
V
-
M
L
L
T
G
R
H
D
P
A
V
H
A
F
Y
E
S
C
G
F
V
Q
N
K
T
G
-----------------------------
83
HHSearch
66.41
22%
-112
- C2 -
2I79
1
?
A:
[6-170]
----------------------------------------------------------------------------------------------------------------------------------------------------
L
I
R
E
A
E
P
K
D
A
A
E
L
V
A
-
F
L
N
R
V
S
L
E
T
D
F
T
S
-----
L
DGDGIL
L
---
T
S
E
E
M
E
I
F
L
---------
N
K
Q
A
S
S
D
---
N
Q
----
I
T
L
L
A
F
L
-
N
G
K
--
I
A
G
I
V
N
I
T
A
D
Q
R
K
R
---------------------------
V
R
H
I
G
D
L
-
F
I
V
I
G
K
R
Y
W
N
N
G
L
G
S
L
L
L
E
E
A
I
E
W
A
Q
A
S
G
I
L
-
R
R
L
-
Q
L
T
V
Q
T
R
N
Q
A
A
V
H
L
Y
Q
K
H
G
F
V
I
E
G
S
Q
E
R
G
AYI
E
---
E
G
K
F
I
D
V
Y
L
M
G
K
L
------
86
Fugue
65.76
19%
-101
- C2 -
1P0H
2
MSHD_MYCTU
A:
[6-313]
A
L
D
W
R
SALT
A
D
E
Q
R
S
V
R
A
L
V
T
A
T
T
A
V
D
GVAPVG
E
Q
V
L
R
E
L
GQQR
T
E
H
L
L
V
A
G
SRPGGPII
G
Y
L
N
L
S
P
PG
G
A
M
A
E
L
V
V
HPQSRRRG
I
G
T
A
M
A
R
A
A
L
A
K
T
A
GR
N
Q
F
W
A
H
GTL
D
P
A
R
A
T
A
S
A
L
GLVGV
R
E
L
I
Q
M
R
R
P
LRD
I
P
E
P
T
I
P
D
G
V
V
I
R
T
Y
A
G
T
S
D
D
A
E
L
L
R
-
V
N
N
A
A
F
A
G
H
-
P
E
--------------------------
Q
G
G
W
T
A
V
Q
L
A
E
R
R
G
E
A
WFD
P
D
----
G
L
I
L
A
F
G
-
D
G
R
--
L
L
G
F
H
W
T
K
V
H
P
D
H
P
-----------------------------
G
L
G
E
V
Y
V
L
G
V
D
P
A
A
Q
R
R
G
L
G
Q
M
L
T
S
I
G
I
V
S
L
A
R
R
L
-
V
E
P
A
V
-
L
L
Y
V
E
S
D
N
V
A
A
V
R
T
Y
Q
S
L
G
F
T
T
Y
S
V
D
T
A
Y
---
A
---
L
------------------
84
Fugue
64.94
20%
-72
- C2 -
2CY2
1
?
A:
[1-174]
---------------------------------------------------------------------------------------------------------------------------------------------------V
R
I
R
R
A
G
L
E
D
L
P
G
V
A
R
-
V
L
V
D
T
W
R
A
T
-
Y
R
G
-----
V
------
V
---
P
E
A
F
L
E
G
L
S
Y
E
G
Q
A
E
R
W
A
Q
R
L
K
T
P
T
---
W
P
----
G
R
L
F
V
A
E
-
S
E
S
--
G
E
V
V
G
F
A
A
F
G
P
D
R
A
S
------------------------
G
F
P
G
Y
T
A
E
L
W
A
I
Y
V
L
P
T
W
Q
R
K
G
L
G
R
A
L
F
H
E
G
A
R
L
L
Q
A
E
G
---
Y
G
R
M
L
V
W
V
L
K
E
N
P
K
G
R
G
F
Y
E
H
L
G
G
V
L
L
G
E
R
E
I
E
---
L
---
G
G
A
K
L
W
E
V
A
Y
G
F
D
L
GGHKW
71
HHSearch
63.94
21%
-104
- C2 -
1Z4E
-
?
A:
[6-149]
----------------------------------------------------------------------------------------------------------------------------------------------------
T
I
R
E
A
T
E
G
D
L
E
Q
M
V
H
-
M
L
A
D
D
V
L
G
R
-
K
R
E
-----
R
------
Y
---
E
K
P
L
P
V
S
Y
V
------
R
A
F
K
E
I
K
K
D
K
---
N
N
----
E
L
I
V
A
C
N
-
G
E
E
--
I
V
G
M
L
Q
V
T
F
T
P
Y
L
T
Y
------------------------
Q
-
G
S
W
R
A
T
I
E
G
V
R
T
H
S
A
A
R
G
Q
G
I
G
S
Q
L
V
C
W
A
I
E
R
A
K
E
R
G
-
C
-
H
L
I
-
Q
L
T
T
D
K
Q
R
P
D
A
L
R
F
Y
E
Q
L
G
F
K
A
S
H
E
G
L
----------------------------
80
HHSearch
63.00
19%
-117
- C2 -
2AE6
1
?
A:
[9-162]
----------------------------------------------------------------------------------------------------------------------------------------------------
T
I
R
L
V
A
E
A
D
W
P
A
L
H
A
-
L
D
Q
I
I
-------------------------------------
S
L
A
A
Y
Q
E
K
M
K
D
-----
E
----
T
I
F
V
A
I
S
-
G
Q
Q
--
L
A
G
F
I
E
V
H
P
P
T
S
L
A
---------------------------
A
H
Q
K
Q
W
L
L
S
I
G
V
S
P
D
F
Q
D
Q
G
I
G
G
S
L
L
S
Y
I
K
D
M
A
E
I
S
G
-
I
-
H
K
L
-
S
L
R
V
M
A
T
N
Q
E
A
I
R
F
Y
E
K
H
G
F
V
Q
E
A
H
F
K
E
E
FY-
I
---
N
G
H
Y
C
D
D
Y
Q
Y
A
Y
-------
87
Fugue
62.50
16%
-111
- C2 -
2FIA
-
?
A:
[1-157]
---------------------------------------------------------------------------------------------------------------------------------------------------M
K
I
R
V
A
D
E
K
E
L
P
M
I
L
Q
-
F
L
T
E
V
K
A
Y
M
-
D
V
V
-------------------
G
I
T
Q
W
T
K
D
Y
P
S
Q
G
D
I
Q
E
D
I
T
K
-----
K
----
R
L
Y
L
L
V
H
-
E
E
M
--
I
F
S
M
A
T
F
C
M
E
Q
E
Q
------------------------------
D
F
V
W
L
K
R
F
A
T
S
P
N
Y
I
A
K
G
Y
G
S
L
L
F
H
E
L
E
K
R
A
V
W
E
G
-
R
-
R
K
M
-
Y
A
Q
T
N
H
T
N
H
R
M
I
R
F
F
E
S
K
G
F
T
K
I
H
E
S
L
Q
M
---
N
---
R
L
D
F
G
S
F
Y
L
Y
V
K
E
L
E----
65
HHSearch
62.16
20%
-109
- C2 -
3FNC
8
?
A:
[7-148]
----------------------------------------------------------------------------------------------------------------------------------------------------
H
I
R
K
A
T
N
S
D
A
E
A
I
Q
H
-
V
A
T
T
S
W
H
H
T
-
Y
Q
D
-----
L
------
I
---
P
S
D
V
Q
D
D
F
L
K
R
F
Y
N
V
E
T
L
H
N
R
I
--
S
---
A
T
----
P
F
A
V
L
E
Q
-
A
D
K
--
V
I
G
F
A
N
F
I
E
L
E
-------------------------------
K
G
K
S
E
L
A
A
F
Y
L
L
P
E
V
T
Q
R
G
L
G
T
E
L
L
E
V
G
M
T
L
F
H
V
---
P
-
L
P
M
-
F
V
N
V
E
K
G
N
E
T
A
I
H
F
Y
K
A
K
G
F
V
Q
V
E
E
F
T
E
D
--------------------------
68
HHSearch
61.89
20%
-92
- C2 -
1U6M
2
?
A:
[3-177]
----------------------------------------------------------------------------------------------------------------------------------------------------
L
I
R
S
A
T
K
E
D
G
Q
A
I
A
R
-
L
V
L
V
I
L
K
D
M
-
E
L
P
-----
I
------
L
E
E
V
S
E
E
Q
M
I
D
L
L
A
E
A
T
A
Y
----
P
T
Y
R
Y
G
---
Y
Q
----
R
I
L
V
Y
E
H
-
A
G
E
--
V
A
G
I
A
V
G
Y
P
A
E
D
E
K
I
ID
E
P
L
R
E
V
F
K
K
H
GLAEDVRLFIEE
E
T
L
P
N
E
W
Y
L
D
T
I
S
V
D
E
R
F
R
G
M
G
I
G
S
K
L
L
D
A
L
P
E
V
A
K
A
S
G
-
K
-
Q
A
L
-
G
L
N
V
D
F
D
N
P
G
A
R
K
L
Y
A
S
K
G
F
K
D
V
T
T
M
T
I
---------------------------