@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs0447: (2015-12-01 )
MKITKIEKKKRLYTLELDNTENLYITEDTIVHFMLSKGMIVNAEKLENIKKFAQLSYGKNLGLYYISFKQRTEKEVIKYLQQHDIDSKIIPQIIDNLKSENWINDKNYVQSFIQQNLNTGDKGPYVIKQKLLQKGIKSKIIESELQAINFQDLASKISQKLYKKYQNKLPLKALKDKLMQSLTTKGFDYQIAHTVIQNLEIEKDQELEEDLIYKELDKQYQKLSKKYDQYELKQRIINALMRKGYQYEDIKSALREYL
Atome Classification :
(20 SA)
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........--10--........20........30.......--.40......----..50........60........70........80..---..----------....90...--.....100.......110.......120.......130....-...140-------.....--..150--....----..--..160.-.......170----.-.-.......180.......190......----------.-200....-----...210.......220.......230.......240.......250......----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKITKIEKK--
K
R
--
L
Y
T
L
ELDNTE
N
L
Y
I
T
E
D
T
I
V
H
F
M
LSK
G
--
M
I
V
N
A
E
K
L
E
----
N
I
K
K
F
A
Q
LSYGKNL
G
L
Y
Y
I
SFKQR
T
E
K
E
V
I
K
Y
L
Q
QH---DI----------
D
S
K
I
I
P
Q
I
I
--
D
N
LKSENWIN
D
K
N
Y
V
Q
S
F
I
Q
QNLNTGDKG
P
Y
V
I
K
Q
K
L
L
Q
K
G
I
-
K
S
K
I
I
E
-------
S
E
L
Q
A--I
N
F
Q
---
D
L
A
S
----
K
I
--
S
Q
K
L
-
Y
-
K
K
Y
Q
NKL
P
------
L
-
K
-
A
L
K
D
K
L
M
Q
S
L
TTKGF
D
Y
Q
I
A
H
T
V
I
Q
N----------L-EIE
K
D
Q
E
-----
L
E
E
D
L
I
Y
K
E
L
D
K
Q
Y
Q
K
L
S
K
K
Y
D
Q
Y
E
L
K
Q
R
I
I
N
A
L
M
RKGY
Q
Y
E
D
I
K
S
A
L
R
E
YL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
96.89
30%
-74
- C4 -
3D5L
1
?
A:
[4-205]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
K
I
S
K
I
E
A
Q
KR
K
G
--
R
Y
N
I
Y
L
D
G
K
Y
A
F
P
V
A
E
S
V
L
I
Q
F
R
L
M
K
G
--
T
E
L
D
E
K
Q
I
A
----
A
I
A
T
A
D
Q
Q
A
K
A
Y
S
R
M
L
D
Y
L
S
Y
Q
M
R
T
E
S
D
I
V
K
K
L
K
E
I
---
D
T
----------
P
E
E
F
V
E
P
I
L
--
K
K
L
R
G
Q
Q
L
I
D
D
H
A
Y
A
A
S
Y
V
R
T
M
I
N
T
D
L
K
G
P
G
I
I
R
Q
H
L
R
Q
K
G
I
-
G
E
S
D
I
D
-------
D
A
L
T
Q
--
F
T
P
E
V
Q
A
E
L
A
K
----
K
L
--
A
L
K
L
-
F
-
R
R
Y
-
R
N
Q
P
------
E
-
R
-
R
R
E
Q
K
V
Q
Q
G
L
T
T
K
G
F
S
S
S
V
Y
E
M
I
K
D
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
96.35
31%
-75
- C4 -
3D5L
1
?
A:
[5-205]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
I
S
K
I
E
A
Q
--
K
R
KG
R
Y
N
I
Y
L
D
G
K
Y
A
F
P
V
A
E
S
V
L
I
Q
F
R
L
M
K
G
--
T
E
L
D
E
K
Q
I
A
----
A
I
A
T
A
D
Q
Q
A
K
A
Y
S
R
M
L
D
Y
L
S
Y
Q
M
R
T
E
S
D
I
V
K
K
L
K
E
I
---
D
T
----------
P
E
E
F
V
E
P
I
L
--
K
K
L
R
G
Q
Q
L
I
D
D
H
A
Y
A
A
S
Y
V
R
T
M
I
N
T
D
L
K
G
P
G
I
I
R
Q
H
L
R
Q
K
G
I
-
G
E
S
D
I
D
-------
D
A
L
T
Q
--
F
T
P
E
V
Q
A
E
L
A
K
----
K
L
--
A
L
K
L
-
F
-
R
R
Y
R
N
Q
-
P
------
E
-
R
-
R
R
E
Q
K
V
Q
Q
G
L
T
T
K
G
F
S
S
S
V
-
Y
E
M
I
K
D
------------
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
41
Fugue
86.71
26%
-55
- C4 -
3D5L
1
?
A:
[3-205]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------L
A
K
I
S
K
I
E
A
Q
--
K
R
KG
R
Y
N
I
Y
L
D
G
K
Y
A
F
P
V
A
E
S
V
L
I
Q
F
R
L
M
K
G
--
T
E
L
D
E
K
Q
I
A
----
A
I
A
T
A
D
Q
Q
A
K
A
Y
S
R
M
L
D
Y
L
S
Y
Q
M
R
T
E
S
D
I
V
K
K
L
K
E
I
---
D
T
----------
P
E
E
F
V
E
P
I
L
--
K
K
L
R
G
Q
Q
L
I
D
D
H
A
Y
A
A
S
Y
V
R
T
M
I
N
T
D
L
K
G
P
G
I
I
R
Q
H
L
R
Q
K
G
I
-
G
E
S
D
I
D
-------
D
A
L
T
Q
--
F
T
--------------------------------------------------------------------------------------
P
-----
E
V
Q
A
E
L
A
K
K
L
A
L
K
L
F
R
R
Y
R
N
Q
P
E
R
R
R
E
Q
K
V
Q
Q
G
L
T
T
K
G
F
S
S
S
V
Y
E
M
I
K
D
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
80.87
38%
-66
- C4 -
3E3V
-
?
A:
[55-208]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
D
D
I
S
K
G
Y
N
A
A
L
N
Y
L
S
Y
Q
L
R
T
R
K
E
V
E
D
K
L
R
S
L
---
D
I
----------
H
E
D
Y
I
S
E
I
I
--
N
K
L
I
D
L
D
L
I
N
D
K
N
Y
A
E
S
Y
V
R
T
M
M
N
T
S
D
K
G
P
K
V
I
K
L
N
L
S
K
K
G
I
-
D
D
N
I
A
E
-------
D
A
L
I
L
--
Y
T
D
K
L
Q
V
E
K
G
V
----
T
L
--
A
E
K
L
-
A
-
N
R
Y
-
S
H
D
S
------
Y
-
R
-
N
K
Q
N
K
I
K
Q
S
L
L
T
K
G
F
S
Y
D
I
I
D
T
I
I
Q
E
----------
L
-
D
L
I
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
76.29
38%
-46
- C4 -
3E3V
-
?
A:
[55-208]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
D
D
I
S
K
G
Y
N
A
A
L
N
Y
L
S
Y
Q
L
R
T
R
K
E
V
E
D
K
L
R
S
L
---
D
I
----------
H
E
D
Y
I
S
E
I
I
--
N
K
L
I
D
L
D
L
I
N
D
K
N
Y
A
E
S
Y
V
R
T
M
M
N
T
S
D
K
G
P
K
V
I
K
L
N
L
S
K
K
G
I
-
D
D
N
I
A
E
D
A
L
I
LYT
D
K
L
Q
V
--
E
K
G
V
---
T
L
A
E
----
K
L
--
A
N
R
Y
S
H
-
D
S
Y
R
N
K
--------------
Q
N
K
I
K
Q
S
L
L
T
K
G
F
S
Y
D
I
I
D
T
I
I
Q
E
----------
L
-
D
L
I
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
42
Fugue
68.53
20%
-44
- C4 -
3C1D
-
RECX_ECO57
B:
[8-161]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
P
A
Y
A
R
L
L
D
R
A
V
R
I
L
A
V
R
D
H
S
E
Q
E
L
R
R
K
L
A
A
P
---
I
M
G
KN
G
P
E
E
I
DA
T
A
E
D
Y
E
R
V
I
--
A
W
C
H
E
H
G
Y
L
D
D
S
R
F
V
A
R
F
I
A
S
R
S
R
K
G
-
Y
G
P
A
R
I
R
Q
E
L
N
Q
K
G
I
-
S
R
E
A
T
E
-------
K
A
M
R
E
--
A
D
-
I
---
D
W
A
A
----
L
A
--
R
D
Q
A
-
T
-
R
K
Y
G
E
P
L
P
------
T
V
F
-
S
E
K
V
K
I
Q
R
F
L
L
Y
R
G
Y
L
M
E
D
I
Q
D
I
W
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
HHSearch
62.71
18%
-41
- C4 -
3C1D
-
RECX_ECO57
A:
[10-161]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Y
A
R
L
L
D
R
A
V
R
I
L
A
V
R
D
H
S
E
Q
E
L
R
R
K
L
A
A
P
-----A---------
T
A
E
D
Y
E
R
V
I
--
A
W
C
H
E
H
G
Y
L
D
D
S
R
F
V
A
R
F
I
A
S
R
S
R
-
K
G
Y
G
P
A
R
I
R
Q
E
L
N
Q
K
G
I
-
S
R
E
A
T
E
-------
K
A
M
R
E
--
A
D
I
D
W
A
-
A
L
A
R
----
D
Q
--
A
T
R
K
-
Y
-
G
E
P
--
L
P
T
------
V
-
F
-
S
E
K
V
K
I
Q
R
F
L
L
Y
R
G
Y
L
M
E
D
I
Q
D
I
W
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
60.75
21%
-26
- C4 -
3DFG
-
RECX_XANCP
A:
[22-148]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
A
L
G
L
--
L
V
H
R
E
H
S
K
K
E
L
N
R
K
L
Q
A
R
---
G
I
----------
E
P
E
A
A
Q
A
A
V
--
E
R
L
A
G
E
G
W
Q
D
D
V
R
F
A
A
S
V
V
R
N
R
A
S
S
G
-
Y
G
P
L
H
I
R
A
E
L
G
T
H
G
L
-
D
S
D
A
V
S
-------
A
A
M
A
T
--
F
E
-
G
---
D
W
T
E
----
N
A
--
L
D
L
I
-
R
-
R
R
F
G
E
D
G
P
------
V
-
D
L
A
Q
R
R
K
A
A
D
L
L
A
R
R
G
F
D
G
N
S
I
R
L
A
T
R
F
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
59.22
15%
-33
* C4 *
3E3V
-
?
A:
[62-205]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
Y
N
A
A
L
N
Y
L
S
Y
Q
L
R
T
R
K
E
V
E
D
K
L
R
S
L
D
I
-
H
E
D
Y
I
S
-------
E
I
I
N
K
--
L
I
D
L
DL-
I
N
D
K
----
N
Y
--
A
E
S
Y
-
V
-
R
T
M
M
-
N
-
T
------
S
-
D
-
K
G
P
K
V
I
K
L
N
L
S
K
K
G
I
D
D
N
I
A
E
D
A
L
I
L
----------
Y
-
T
D
K
---------
L
Q
V
E
K
G
V
T
L
A
E
K
L
A
N
R
Y
S
H
-
D
S
Y
R
N
K
Q
N
K
I
K
Q
S
L
L
T
K
G
F
S
Y
D
I
I
D
T
I
I
Q
E
L
D
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
HHSearch
58.42
16%
-26
- C4 -
3C1D
-
RECX_ECO57
A:
[15-161]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
D
R
A
V
R
I
L
A
V
R
D
H
S
E
Q
E
L
R
R
K
L
A
A
P
--A
T
A
E
D
Y
E
-------
R
V
I
A
W
--
C
H
E
H
GY-
L
D
D
S
----
R
F
--
V
A
R
F
-
I
-
A
S
R
S
---
R
------
K
-
G
-
Y
G
P
A
R
I
R
Q
E
L
N
Q
K
G
I
S
R
E
A
T
E
K
A
M
R
E
----------
A
-
D
I
D
----------
W
A
A
L
A
R
D
Q
A
T
R
K
Y
G
E
P
L
--
P
T
V
F
S
E
K
V
K
I
Q
R
F
L
L
Y
R
G
Y
L
M
E
D
I
Q
D
I
W
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
HHSearch
57.78
15%
-31
- C4 -
3D5L
-
?
A:
[63-205]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Y
S
R
M
L
D
Y
L
S
Y
Q
M
R
T
E
S
D
I
V
K
K
L
K
E
I
D
T
-
P
E
E
F
V
E
-------
P
I
L
K
K
--
L
R
G
Q
QL-
I
D
D
H
----
A
Y
--
A
A
S
Y
-
V
-
R
T
M
I
--
N
T
------
D
-
L
-
K
G
P
G
I
I
R
Q
H
L
R
Q
K
G
I
G
E
S
D
I
D
D
A
L
T
Q
----------
F
-
T
P
E
---------
V
Q
A
E
L
A
K
K
L
A
L
K
L
F
R
R
Y
R
N
-
Q
P
E
R
R
R
E
Q
K
V
Q
Q
G
L
T
T
K
G
F
S
S
S
V
Y
E
M
I
K
D
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
54.92
27%
-24
- C4 -
3C1D
-
RECX_ECO57
A:
[58-134]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
V
I
--
A
W
C
H
E
H
G
Y
L
D
D
S
R
F
V
A
R
F
I
A
S
R
S
R
K
G
-
Y
G
P
A
R
I
R
Q
E
L
N
Q
K
G
I
-
S
R
E
A
T
E
-------
K
A
M
R
E
--
A
D
I
----
D
W
A
A
----
L
A
--
R
D
Q
A
-
T
-
R
K
Y
G
E
P
L
P
------
T
-
V
-
F
S
E
K
V
K
I
Q
R
F
L
L
Y
R
G
Y
L
M
E
D
I
Q
D
I
W
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
43
Fugue
51.75
20%
-11
- C1 -
4TQT
8
?
A:
[14-490]
------------------------------------------------------A
S
K
V
I
K
G
G
T
V
I
T
AD
R
T
F
R
A
D
I
L
I
E
DGKIAAIGD
S
L
E
G
D
E
V
I
D
ASG
C
Y
V
M
PG
G
I
D
P
H
T
H
L
QMPFMGTYSSDD
F
D
T
G
T
A
A
A
L
A
G
GTT
M
V
V
D
F
V
L
P
D
SEGN
L
L
D
A
L
Q
E
W
F
Q
K
A
G
KAR
T
D
Y
S
F
H
M
A
I
T
G
W
N
E
R
--
T
F
--
N
E
M
A
E
V
V
K
R
G
I
------
N
T
F
H
F
M
A
Y
K
G
A
L
M
V
N
D
D
E
M
F
A
----
S
F
Q
R
C
A
E
L
G
A
---
M
P
L
V
H
A
---------------------
E
----------
N
G
D
I
V
A
Q
L
Q
--
A
K
L
M
A
E
-------------------
G
N
D
G
P
E
A
H
A
Y
---------
S
R
P
P
E
-------
V
E
G
E
A
--
T
N
R
A
I
--
M
I
A
D
----
Q
A
--
G
V
P
L
-
Y
V
V
H
V
S
C
E
Q
S
------
H
-
E
-
A
I
R
R
A
R
Q
K
G
M
R
V
F
G
-
E
P
L
I
Q
H
L
T
L
D
E
----------
S
-
E
Y
H
-------------------
N
R
D
W
D
Y
A
A
R
---------
R
V
M
S
P
P
F
R
D
K
L
N
Q
D
S
L
W
A
G
L
A
A
G
S
L
Q
C
V
A
T
D
H
C
A
F
T
T
E
Q
K
R
Y
GIGNFTKI
P
N
G
T
G
G
LEER
M
P
V
L
W
T
R
GVRTGRLT
P
N
E
F
V
A
V
T
S
T
N
I
A
K
I
L
NIYPQKGAVVPGADAD
L
V
I
W
D
PE
T
T
K
K
ISAKTQHSSIDYNVFEG
F
E
L
K
G
LPI
M
T
L
S
RGRIAFDKGQVTAKPGD
G
R
F
I
E
R
E
P
NG
A
V
N
R
A
L
S
Q
W
K
E
I
V
A
P
R
K
V
E
R
S
A
7
PsiBlast_PDB
51.65
27%
-56
- C4 -
1Z25
-
?
A:
[455-531]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
G
--
I
I
---
E
V
V
E
----
Q
V
S
S
F
M
K
---
G
K
E
L
G
L
A
F
I
A
A
R
N
K
L
S
S
E
K
F
E
E
I
K
R
R
---
L
F
----------
N
L
N
V
I
S
Q
V
V
N
E
D
T
L
K
N
K
R
D
K
Y
D
R
N
R
L
D
L
F
V
R
H
N
L
L
F
Q
V
L
S
K
L
G
V
K
Y
Y
V
L
D
Y
R
F
-
N
Y
D
Y
I
I
-------
G
I
D
V
A
--
P
M
K
R
---
S
E
G
Y
----
I
G
--
G
S
A
V
-
M
-
F
D
S
Q
G
Y
I
R
------
K
-
I
-
V
P
I
K
I
G
E
Q
R
G
E
S
V
D
M
N
E
F
F
K
E
M
V
D
K
F
----------
K
-
E
F
N
I
K
L
D
-----
N
K
K
I
L
L
L
R
D
G
R
I
T
N
N
E
E
E
G
L
K
Y
I
S
E
M
F
D
I
E
V
V
T
M
D
V
I
K
N
H
P
V
R
A
F
A
N
M
K
M
Y
F
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
49.89
23%
7
- C4 -
4KBL
-
ARI1_HUMAN
A:
[425-550]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
H
M
Q
S
--
L
R
F
E
H
--
K
L
Y
A
----
Q
V
--
K
Q
K
M
-
E
---------WIEVQF
L
-
K
-
K
A
V
D
V
L
C
Q
C
R
A
T
L
M
Y
T
Y
V
F
A
F
Y
L
K
K
N
N
Q
S
I
I
F
E
N
N
Q
A
-
D
L
E
N
A
T
E
V
L
S
G
Y
L
E
R
D
I
S
Q
D
S
L
Q
D
I
K
Q
K
V
Q
D
K
Y
R
Y
C
E
S
R
R
R
V
L
L
Q
H
V
H
E
G
Y
E
K
D
L
W
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
49.37
27%
-52
- C4 -
1Z26
-
?
A:
[455-531]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
G
--
I
I
---
E
V
V
E
----
Q
V
S
S
F
M
K
---
G
K
E
L
G
L
A
F
I
A
A
R
N
K
L
S
S
E
K
F
E
E
I
K
R
R
---
L
F
----------
N
L
N
V
I
S
Q
V
V
N
E
D
T
L
K
N
K
R
D
K
Y
D
R
N
R
L
D
L
F
V
R
H
N
L
L
F
Q
V
L
S
K
L
G
V
K
Y
Y
V
L
D
Y
R
F
-
N
Y
D
Y
I
I
-------
G
I
D
V
A
--
P
M
K
R
---
S
E
G
Y
----
I
G
--
G
S
A
V
-
M
-
F
D
S
Q
G
Y
I
R
------
K
-
I
-
V
P
I
K
I
G
E
Q
R
G
E
S
V
D
M
N
E
F
F
K
E
M
V
D
K
F
----------
K
-
E
F
N
I
K
L
D
-----
N
K
K
I
L
L
L
R
D
G
R
I
T
N
N
E
E
E
G
L
K
Y
I
S
E
M
F
D
I
E
V
V
T
M
D
V
I
K
N
H
P
V
R
A
F
A
N
M
K
M
Y
F
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
45
Fugue
47.69
15%
13
* C5 *
2PTR
1
PUR8_ECOLI
A:
[1-459]
MELSSLTAVSPVDGRYGDKV
S
A
L
R
G
I
FS
E
Y
G
L
L
K
F
R
V
Q
V
E
V
R
W
L
Q
K
L
A
A
HAAIKEVPAFA
A
D
A
I
G
Y
L
D
A
I
V
A
S
FS
E
E
D
A
A
R
I
K
T
I
E
R
T
TNH
D
V
K
A
V
E
Y
F
L
K
E
K
V
AEI
P
E
L
H
A
V
SEFIHFACT
S
E
D
I
N
N
L
S
H
A
L
M
L
K
T
A
R
D
EV
I
L
P
Y
W
R
Q
L
I
D
G
L
K
D
L
A
V
Q
Y
R
DIPLLSRTAGQP
A
T
P
S
T
I
G
K
E
--
M
A
--
N
V
A
Y
R
M
E
R
Q
Y
R
Q
L
N
Q
V
E
I
L
G
K
I
N
G
A
V
G
--
N
Y
-
N
A
H
I
A
A
Y
PEV
D
W
H
Q
F
S
E
-
E
F
V
T
S
L
G
I
Q
W
N
P
Y
T
T
Q
I
E
P
H
--
D
Y
I
A
E
L
---
F
D
----------
C
V
A
R
F
N
T
I
L
--
I
D
F
D
R
D
V
W
G
Y
I
A
---
L
N
H
F
K
Q
K
T
I
A
G
E
I
G
---------------
S
S
T
M
P
-------
H
K
V
N
P
--
I
D
F
E
---
N
S
E
G
----
N
L
G
L
S
N
A
V
-
L
-
Q
H
L
A
S
K
L
P
------
V
-
S
-
R
W
Q
R
D
L
T
D
S
T
V
L
R
N
L
G
V
G
I
G
Y
A
L
I
A
Y
----------
Q
-
S
T
L
K
G
V
S
K
LE--
V
N
R
D
H
L
L
D
E
L
D
H
N
W
E
V
L
A
E
P
I
Q
T
V
M
R
R
Y
G
I
E
K
-------
P
Y
E
K
L
K
E
L
V
D
A
E
G
M
K
Q
F
I
D
G
LALP
E
E
E
K
A
R
L
K
A
MTPANYIGR
A
I
T
M
V
D
E
LKHHH-----------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
46.66
20%
-14
- C4 -
3OHM
-
PLCB3_HUMAN
B:
[140-279]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
I
L
A
Q
N
A
S
R
N
T
F
L
R
K
A
Y
T
K
L
K
L
Q
V
N
Q
D
G
R
I
P
V
K
N
I
L
K
M
F
S
A
-
D
K
K
R
V
E
-------
T
A
L
E
S
C
G
L
K
F
N
---
R
S
E
S
I
R
PD
E
F
--
S
L
E
I
-
F
-
E
R
F
L
N
K
L
C
------
L
-
R
-
P
D
I
D
K
I
L
L
E
I
G
A
K
G
K
P
Y
L
T
L
E
Q
L
M
D
F
----------
I
N
Q
K
Q
R
D
P
R
-----
L
N
E
V
L
Y
P
P
L
R
P
S
Q
A
R
L
L
I
E
K
Y
E
P
N
Q
Q
F
L
E
R
D
Q
M
S
M
E
G
F
S
R
Y
L
G
G
E
E
N
G
I
L
P
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
46.29
20%
-24
- C4 -
4GNK
-
PLCB3_HUMAN
B:
[142-281]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
I
L
A
Q
N
A
S
R
N
T
F
L
R
K
A
Y
T
K
L
K
L
Q
V
N
Q
D
G
R
I
P
V
K
N
I
L
K
M
F
S
A
-
D
K
K
R
V
E
-------
T
A
L
E
S
C
G
L
K
F
N
---
R
S
E
S
IRPD
E
F
--
S
L
E
I
-
F
-
E
R
F
L
N
K
L
C
------
L
-
R
-
P
D
I
D
K
I
L
L
E
I
G
A
K
G
K
P
Y
L
T
L
E
Q
L
M
D
F
----------
I
N
Q
K
Q
R
D
P
R
-----
L
N
E
V
L
Y
P
P
L
R
P
S
Q
A
R
L
L
I
E
K
Y
E
P
N
Q
Q
F
L
E
R
D
Q
M
S
M
E
G
F
S
R
Y
L
G
G
E
E
N
G
I
L
P
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
HHSearch
45.35
24%
-47
- C4 -
3HHH
1
?
A:
[17-64]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
V
L
A
I
I
Q
R
K
E
T
Y
G
Y
E
I
T
K
I
L
N
D
Q
GFT
E
I
----------
V
E
G
T
V
Y
T
I
L
--
L
R
L
E
K
N
Q
W
V
I
A
E
K
K
P
S
E
P
M
R
K
F
Y
R
L
T
S
S
G
E
A
E
L
A
D
F
W
Q
R
W
T
L
-
L
S
K
Q
V
N
-------
K
M
K
K
N
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------