@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv0004: (2016-04-18 )
MTGSVDRPDQNRGERSMKSPGLDLVRRTLDEARAAARARGQDAGRGRVASVASGRVAGRRRSWSGPGPDIRDPQPLGKAARELAKKRGWSVRVAEGMVLGQWSAVVGHQIAEHARPTALNDGVLSVIAESTAWATQLRIMQAQLLAKIAAAVGNDVVRSLKITGPAAPSWRKGPRHIAGRGPRDTYG
Atome Classification :
(20 SA)
--------.....------..-..10.-.....---..20........---------.30......--------------..40........50........60....------....70........80..-----...-..-.90........--------100.---......110----.---..-...--.120--.....---..130.....--.-.-140.......150....-...160.....----..170........180-......--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--------MTGSV------DR-PDQNR-GERSM---KSP-
G
L
D
L
V
R
R
T
---------
L
D
E
A
R
A
A
A
R--------------ARGQDAGRGR
V
A
S
VASGRVAGRRRSWSG------PGPDIRDP
Q
P
L
G
K
A
A
R
E
L
-----
A
K
K-RG-
W
S
V
R
VAE
G
M
V
L
--------G
Q
W
S
---
A
V
V
G
H
Q
I
A
E
----H---AR-PTA--LN
D
G
--
V
L
S
V
I
---
A
EST
A
W
A
T
Q
L
--
R
-
I
-
M
Q
A
Q
L
L
A
K
I
A
A
A
V
G
N
D
V
-
V
R
S
L
KITGPAA----PSW-RKGPRHIAGRG--PRDTYG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
Fugue
85.26
17%
-16
* C5 *
5FRU
1
?
A:
[14-208]
DGLS
N
L
A
R
R
L
R
F
A
------
M
K
-
E
G
S
I
W
L
G
E
Q
R
M
I
L
L
H
T
A
-
A
L
G
A
L
R
K
E
---------
L
V
D
T
L
G
M
E
R
--------------
A
R
G
L
F
M
R
M
G
F
H
S
G
V
R
D
A
E
L
A
K
T
M
R
----------
S
G
H
S
D
F
G
M
L
E
M
G
P
C
L
H
T
I
E
GV
V
R
V
T
P
-
L
T
-
V
D
I
N
I
A
A
G
V
Y
H
--------
G
E
F
L
---
W
E
D
S
F
E
G
D
V
----
H
---
R
Q
-
M
F
G
--
V
A
Q
A
PV
C
W
M
Q
I
---
G
Y
A
T
G
Y
T
S
A
L
--
M
-
G
-
K
T
I
L
Y
R
E
L
E
C
V
G
C
G
H
P
----
H
C
R
I
L
G
K
P
L
----
E
Q
W
-
E
D
G
E
A
E
L
A
L
Y
Q
--
P
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
Fugue
77.07
16%
-29
* C7 *
2CWO
-
P21_BYVU
A:
[1-177]
--------
M
K
F
F
L
------
K
D
-
G
E
T
S
R
-
A
L
S
R
S
---
E
S
L
-
L
R
R
V
--
K
E
---------
L
G
T
N
S
Q
Q
S
E
--------------
I
S
E
C
V
D
E
F
N
E
L
A
S
F
N
H
L
L
V
T
V
E
H
R
E
W
M
--------------
E
Q
R
I
G
E
M
L
K
E
I
-----
R
A
F
-
L
---
K
V
R
V
V
T
P
M
H
K
--------
E
T
A
S
---
D
T
L
N
A
F
L
E
E
----
Y
---
C
R
-
I
T
G
--
L
A
-------------
R
E
D
A
L
R
E
K
M
--
R
-
K
-
V
K
S
V
V
L
F
H
H
S
E
L
L
K
F
E
V
-
T
E
N
M
-
F
S
Y
T
E
L
----
L
K
L
-
N
L
S
L
R
V
I
S
S
Q
I
--
L
G
M
A
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
Fugue
68.25
16%
-12
- C4 -
1JJ2
-
RL4_HALMA
C:
[1-246]
--------
M
Q
A
T
I
Y
D
LDGN
T
D
-
G
E
V
D
L
-
P
D
V
F
E
---
T
P
V
-
R
S
D
L
I
G
K
A
---------
V
R
A
A
Q
A
N
R
K
Q
D
Y
G
S
DEYAGLRTP
A
E
S
F
G
S
G
R
G
Q
A
H
V
P
K
L
D
G
R
A
R
R
V
P
Q
A
V
K
GRSAHP
P
K
T
E
K
D
R
S
L
D
L
N
D
K
E
R
Q
L
-----
A
V
R
-
S
A
-
L
A
A
T
A
D
A
D
L
V
A
D
R
G
H
E
F
DR
D
E
V
P
---
V
V
V
S
D
D
F
E
D
----
L
---
V
K
-------
T
Q
E
--
V
V
S
L
L
---
E
A
L
D
V
H
A
D
I
D
--
R
-
A
-
D
E
T
K
I
K
A
G
Q
G
S
A
R
G
R
K
Y
-
R
R
P
A
S
I
L
F
V
T
S
----
D
E
P
-
S
T
A
A
R
N
L
A
G
A
D
--
V
A
T
A
S
E
VNTEDLAPGGAPGRL
T
V
F
T
E
S
A
L
A
E
V
A
ER---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
65.14
25%
-32
- C6 -
4A56
1
PULS_KLEPN
A:
[2-75]
-------------------------------------------------------------------------------------
S
G
Q
A
Q
L
E
Q
L
A
S
V
A
A
G
A
R
Y
L
K
N
K
C
------
N
R
S
D
L
P
A
D
E
A
I
N
R
A
A
I
N
V
-----
G
K
K
-
R
G
-
W
A
--
N
I
D
A
N
L
L
--------
S
Q
R
S
---
A
Q
L
Y
Q
Q
L
Q
Q
----
D
---
S
T
-
P
E
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
59.82
27%
2
- C6 -
4EM6
-
G6PI_BRUME
D:
[438-526]
----------------------------------------------
R
T
---------
L
D
E
A
R
A
Q
L
Q
--------------
A
K
N
L
P
A
--
S
Q
V
E
R
I
A
P
H
R
V
F
S
G
N
R
P
S
L
T
------
L
I
H
D
M
L
D
P
Y
T
L
G
R
L
I
A
L
Y
-----
E
H
R
-
V
F
-
V
E
A
Q
I
F
G
I
N
A
F
--------
D
Q
W
G
---
V
E
L
G
K
E
L
A
T
----
E
---
L
L
-
P
V
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
Fugue
59.29
23%
-6
- C3 -
2K3M
3
?
A:
[25-151]
--------
M
S
D
----------------------------------------------
F
D
T
E
R
V
S
R
A
--------------
V
A
A
A
L
V
G
P
G
G
V
A
L
V
V
K
V
C
A
--------
G
------
L
P
G
V
I
H
T
P
A
----------------
R
-
R
G
-
F
F
R
C
N
P
E
R
I
Q
I
--------
G
D
W
R
-------
Y
E
V
A
H
----
D
---
G
R
-
L
L
A
--
A
H
M
V
--
N
G
I
V
I
---
A
E
D
A
L
I
A
E
A
V
--
G
-
P
-
H
L
A
R
A
L
G
Q
I
V
C
R
Y
G
A
T
V
-
I
P
N
I
N
A
A
I
E
V
L
----
G
T
------------
G
--
T
D
Y
R
F
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
Fugue
56.39
18%
-23
- C5 -
4UN1
1
?
B:
[21-179]
--------
M
S
H
Q
F
------
S
P
-
E
E
Q
A
V
-
L
R
I
V
Q
---
A
N
L
-
P
D
S
L
T
-------------
P
Y
A
D
L
A
E
Q
--------------
A
G
M
T
E
A
Q
V
L
E
L
L
G
R
L
K
A
S
G
A
I
R
R
-----------
F
G
A
S
I
K
H
-----------------
Q
K
-
T
G
-
W
T
-----
H
N
A
M
--------
V
A
W
K
----
V
T
P
D
Q
V
D
D
----
C
---
G
R
-
K
A
A
--
E
H
S
H
--
I
S
H
V
Y
Y
R
P
S
S
A
P
D
W
P
Y
E
M
--
Y
-
T
-
M
I
H
G
R
S
E
A
E
C
L
G
V
V
E
D
V
-
K
R
T
T
S
L
K
E
H
A
I
----
L
R
S
-
L
K
E
L
K
K
T
S
M
T
Y
--
F
T
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
54.61
33%
-50
- C6 -
3VTF
-
?
A:
[349-410]
---------------------------------------------------------------------------------------------------------------------
D
V
R
E
S
R
--
G
V
E
V
A
R
L
-----
L
L
E
-
R
G
-
A
R
V
Y
V
H
D
P
M
A
M
--------
E
K
A
R
---
A
V
L
G
D
S
V
T
Y
----
V
---
E
D
-
P
Q
A
--
L
L
D
Q
--
V
E
G
V
I
---
I
-
A
T
A
W
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
Fugue
53.39
19%
4
- C7 -
4U3E
6
?
A:
[12-670]
------SG
L
V
G
S
--------
H
M
K
V
Q
Y
S
-
F
E
R
E
F
---
E
E
L
M
S
-
D
L
L
S
K
Y
G
Y
E
M
F
Q
M
D
G
L
G
D
Q
L
D
V
V
K
--------------
F
T
E
D
F
V
R
R
G
I
I
E
S
T
I
D
A
N
A
N
V
R
V
T
N
I
S
T
------
Y
F
I
E
I
S
K
P
H
T
Y
L
Y
S
L
Y
R
I
-----
W
Q
K
M
K
E
M
F
G
K
G
V
A
D
E
F
V
E
--------
A
Q
I
N
G--
A
V
Y
L
H
D
R
H
H
----
A
---
A
L
M
P
Y
C
--
F
A
Y
T
--
L
K
P
I
V
---
E
K
G
L
P
F
I
K
T
I
--
K
-
S
-
E
P
A
K
H
L
S
T
F
I
Q
H
V
I
Q
F
V
M
F
A
S
N
Q
S
S
G
A
V
G
LPD
F
F
V
W
M
W
Y
F
V
K
K
D
L
K
E
G
II
P
R
D
K
L
D
W
Y
I
E
Q
H
F
Q
I
L
T
Y
S
L
N
QPIRTTQSP
Y
T
N
F
T
YLD
R
N
Y
I
K
A
I
F
EGERYPDGSLITDH
V
E
D
I
I
A
L
Q
K
H
Y
W
E
W
V
S
R
E
R
E
R
Q
M
F
T
F
P
V
L
T
A
S
L
L
Y
K
DGKFLD
E
D
S
A
R
F
I
N
K
I
N
MKWQD
T
N
W
Y
I
S
DSIDAVASCE
K
L
K
G
R
M
N
SIGGSDLNIGSF
K
V
I
T
V
N
L
P
R
I
A
L
E
S
G
GD
R
E
K
Y
L
Q
I
L
R
H
R
V
Q
L
I
K
K
A
L
A
A
V
R
E
I
I
K
E
R
I
S
E
GLLPLYENGLMLLNRQYGTIGVTG
V
W
E
S
A
S
I
M
GL
T
T
E
D
ID
G
L
K
Y
T
E
E
G
E
V
F
V
D
N
V
L
D
T
I
R
E
E
A
E
K
G
Y
H
E
YG
F
T
F
N
I
E
QVPAE
K
A
A
V
T
L
A
Q
K
D
R
F
L
FGEKQPFEIYSNQWVPLMANTD
V
L
N
R
I
R
Y
S
G
K
W
D
KKVSGG
A
I
L
H
I
N
L
GESFKT
E
E
E
S
F
N
M
V
K
M
I
A
D
M
GVM
Y
F
A
F
N
T
K
I
S
V
C
EDG
H
A
F
Y
G
ERCPVCGKAKV
D
E
Y
M
RIVG
Y
L
V
P
V
S
A
F
N
K
E
R
R
E
I
E
Y
P
R
R
QFYDSLTIR
11
HHSearch
52.91
17%
-105
- C6 -
2E0G
-
DNAA_ECOLI
A:
[27-75]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
---
L
Q
-
A
E
---
L
S
D
N
--
T
L
A
L
Y
---
A
P
N
R
F
V
L
D
W
V
--
R
D
K
-
Y
L
N
N
I
N
G
L
L
T
S
F
C
G
A
D
A
--
P
Q
L
R
F
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
52.52
9%
-128
- C6 -
1TH5
-
NIFU1_ORYSJ
A:
[167-224]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
I
R
P
Y
L
A
G
T
GGG
G
---
L
Q
-
F
L
M
--
I
K
G
P
--
I
V
K
V
R
---
L
T
G
P
A
A
--
V
V
--
R
-
T
-
V
R
I
A
V
S
K
K
L
R
E
K
I
P
S
---
I
Q
I
V
Q
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
HHSearch
52.50
7%
-121
- C6 -
2M5O
-
A:
[28-92]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
---
T
R
I
R
P
T
V
Q
E
----
D
G
G
D
V
I
-
Y
K
G
--
F
E
D
G
--
I
V
Q
L
K
---
L
Q
G
S
C
T
S
C
P
S
S
I
I
-
T
-
L
K
N
G
I
Q
N
M
L
Q
F
Y
I
P
E
---
V
E
G
V
E
Q
V
M
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
Fugue
47.39
18%
34
* C6 *
1X9B
-
?
A:
[1-53]
------------
R
------
N
L
-
S
D
R
A
K
-
F
E
S
M
I
---
N
S
P
-
S
K
S
V
F
V
R
N
---------
L
N
E
L
E
A
L
A
V
--------------
R
L
G
----
K
S
Y
R
I
Q
L
D
Q
A
K
E
K
W
K
V
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
45.10
14%
-110
- C6 -
4TPS
-
DNAA_BACSU
B:
[33-75]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
---
T
K
-
A
H
S
--
L
Q
G
D
--
T
L
T
I
T
---
A
P
N
E
F
A
R
D
W
L
--
E
-
S
R
Y
L
H
L
I
A
D
T
I
Y
E
L
T
G
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
42.46
17%
-77
- C6 -
5FKV
-
DPO3X_ECOLI
E:
[537-583]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
Q
V
A
L
----
N
---
A
W
-
K
E
E
---
S
D
N
--
A
V
C
L
H
---
L
R
S
-
S
Q
R
H
L
N
--
N
R
G
-
A
Q
Q
K
L
A
E
A
L
S
M
L
K
G
S
T
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
41.75
10%
-67
- C6 -
2JMP
-
DNAA_MYCGE
A:
[28-75]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
---
I
N
-
R
F
V
--
F
K
N
N
--
V
L
L
I
L
---
L
E
N
E
F
A
R
N
S
L
--
N
-
D
-
N
S
E
-
I
I
H
L
A
E
S
L
Y
E
G
I
---
K
S
V
N
F
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
41.35
37%
-23
- C6 -
3UBR
2
NRFA_SHEON
A:
[339-384]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
W
R
W
D
L
A
I
A
S
H
G
V
A
A
----
H
---
A
P
-
E
E
A
--
L
R
-------
V
L
---
G
T
S
V
N
K
A
A
D
A
--
R
-
V
-
K
L
A
Q
L
L
A
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
38.59
10%
-107
- C6 -
2WP0
-
DNAA_HELPY
C:
[33-75]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
K
-
Y
N
P
NA
S
K
S
D
--
I
A
F
F
Y
---
A
P
N
Q
V
L
C
T
T
I
--
T
A
K
-
Y
G
A
L
L
K
E
I
L
S
Q
N
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
36.41
59%
88
- C6 -
3VPS
1
?
A:
[243-264]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
D
V
-
I
R
I
L
Q
A
T
S
P
A
A
----
E
V
A
-
R
K
Q
P
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
Fugue
29.01
20%
36
- C5 -
2L92
-
?
A:
[71-114]
------------------------------------------------------------------------------------------
M
S
T
V
P
K
Y
R
D
P
A
T
G
K
T
W
S
G
------
R
G
R
Q
---
P
A
W
L
G
N
D
P
A
A
F
-----
L
I
Q
-
P
D
-
L
P
A
I
L
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------