@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv0140: (2016-04-19 )
MSNRIVLEPSADHPITIEPTNRRVQVRVNGEVVADTAAALCLQEASYPAVQYIPLADVVQDRLIRTETSTYCPFKGEASYYSVTTDAGDIVDDVMWTYENPYPAVAAIAGHVACYPDKAEISIFPG
Atome Classification :
(20 SA)
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10........20------.---.....-----..30........40......-.-------------------.-50.---..-.....60........-----70....-....80.......-.---90........100.----......-110...--....120....-------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSN
R
I
V
LEPSADH
P
I
T
I
EPTN------
R
---
R
V
Q
V
R
-----VN
G
E
V
V
A
D
T
A
A
A
L
C
L
Q
EASY-P-------------------
A
-
V
Q
Y
---I
P
-
L
A
D
V
V
Q
D
R
L
IRTETS-----TYCPFK-GEA
S
Y
Y
S
V
TTD
A
G
-
D
---
I
V
D
D
V
M
W
TYENPY
P
----
A
V
A
A
IA-GHVACY--PDK
A
E
I
SIFPG-------------------------------------------------------------------------------------
1
PsiBlast_PDB
92.45
33%
-134
- C5 -
3DJM
2
?
A:
[5-116]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
N
H
I
R
L
R
K
A
E
------
G
---
K
W
V
I
R
-----
T
D
S
A
V
L
G
E
T
L
N
A
I
E
L
T
E
G
S
R
-
D
-------------------
P
-
V
I
Y
---
F
P
-
R
E
D
V
A
M
V
M
F
D
K
S
E
K
V
-----
T
A
C
P
L
K
-
G
E
A
S
Y
Y
S
I
V
G
A
S
G
-
T
---
L
-
K
D
A
A
W
S
Y
E
S
P
K
E
----
G
L
E
A
I
A
-
G
Y
L
A
F
A
--
P
D
C
T
K
V
G
Q
Y
---------------------------------------------------------------------------------------
23
HHSearch
91.51
34%
-136
- C5 -
3DJM
-
?
A:
[4-114]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
N
N
H
I
R
L
R
K
A
E
------
G
---
K
W
V
I
R
-----
T
D
S
A
V
L
G
E
T
L
N
A
I
E
L
T
E
G
-
S
R
D
-------------------
P
-
V
I
Y
---
F
P
-
R
E
D
V
A
M
V
M
F
D
K
S
E
K
V
-----
T
A
C
P
L
K
-
G
E
A
S
Y
Y
S
I
V
G
-
A
S
-
G
---
T
L
K
D
A
A
W
S
Y
E
S
P
K
E
----
G
L
E
A
I
A
-
G
Y
L
A
F
A
--
P
D
C
T
K
V
G
-----------------------------------------------------------------------------------------
41
Fugue
67.32
23%
-72
* C6 *
4J1V
3
MOB1A_HUMAN
A:
[9-180]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
R
Q
A
V
M
L
P
E
G
E
D
L
N
E
W
I
A
V
N
T
------
V
---
D
F
F
N
Q
-----
I
N
--
M
L
Y
G
T
I
T
E
F
C
-
T
E
A
S
C
-
P
VMSAGPR
Y
E
Y
H
WADP
I
K
C
S
A
-
P
K
Y
---
I
D
Y
L
M
T
W
V
Q
D
Q
L
---
D
D
E
-----
T
L
F
P
S
K
I
G
V
P
F
P
K
N
F
M
S
V
A
K
-
T
---
I
L
K
R
L
F
R
V
Y
A
H
I
Y
H
QH
F
D
S
V
M
Q
L
Q
-
E
E
A
H
L
N
--
T
S
F
K
H
F
I
F
F
V
Q
E
FNLIDRRELAPL
Q
E
L
I
E
K
L
G----------------------------------------------------------------
42
Fugue
58.47
20%
-45
- C6 -
2HW4
16
PHP14_HUMAN
A:
[18-141]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L
Y
F
Q
S
M
D
L
A
L
I
P
D
V
D
I
D
S
D
G
V
F
------
K
---
Y
V
L
I
R
-----
V
H
------
S
A
E
S
K
E
I
V
R
G
Y
K
-
W
-------------------
A
-
E
Y
H
---
A
D
-
I
Y
D
K
V
S
G
D
M
Q
K
Q
G
C
D
-----
C
E
C
L
G
G
-
G
R
I
S
H
Q
S
--
Q
D
K
K
-
I
---
H
V
Y
G
Y
S
M
A
Y
-
G
P
A
Q
----
H
A
I
S
T
E
-
K
I
K
A
K
Y
--
P
D
Y
-
E
V
T
W
-
A
N
-------------------------------------------------------------------------------------
40
Fugue
57.11
19%
-85
- C2 -
4UUW
5
?
A:
[1-394]
M
E
R
A
E
I
L
G
V
G
T
E
L
L
Y
GETLDT
N
T
A
E
I
A
R
S
L
KPYALKVE
R
T
L
R
V
A
DE
V
A
P
L
A
R
E
V
E
E
A
F
A
R
AR
L
V
V
L
S
G
GLGPTPDDV
T
R
E
A
V
A
L
A
L
G
E
P
L
E
L
D
E
A
V
L
G
E
I
E
A
F
F
R
A
R
GRAMPEANRKQAMRIPS
A
T
W
L
K
N
PRGT
A
P
G
W
W
V
R
K
GG
K
D
L
V
L
L
P
GPPPEW
R
P
M
W
Q
E
V
L
P
R
LGLPRRP
Y
A
E
R
V
L
K
T
W
GIG
E
S
E
I
V
E
R
L
G
P
L
F
V
R
E
E
--
E
V
E
V
G
T
Y
P
K
V
------
H
---
G
V
E
V
V
-----
V
R
G
R
E
D
R
V
A
E
L
A
E
R
I
K
K
K
L
L
-
K
-------------------
E
-
V
W
G
EGE
M
T
-
L
A
E
A
V
K
R
R
M
E
R
E
G
----------------
A
T
L
S
T
M
E
S
L
T
G
-
G
---
L
L
G
A
E
I
---
T
R
V
P
G
----
A
S
R
F
Y
L
-
G
G
V
V
S
Y
S
V
G
A
K
A
R
F
G
V
P
Q
D
LLSRTVS
A
E
T
A
R
A
M
A
E
A
A
R
S
L
F
GST
Y
A
L
A
T
T
G
V
AGPDPLEGEPPGT
V
Y
V
A
L
A
G
PT
G
A
E
V
R
R
Y
R
F
P
G
D
R
E
T
V
R
L
R
S
V
Y
A
A
L
A
L
L
V
T
34
Fugue
54.57
19%
-54
- C5 -
2XXS
-
MXIG_SHIFL
A:
[1-107]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
S
N
L
------
A
P
F
R
L
L
V
K
L
T
N
------
G
---
V
G
D
E
F
P
L
Y
Y
G
N
N
L
I
V
L
G
R
T
I
E
T
L
E
F
G
N
D
N
F
-
P
-------------------
E
--
N
I
---
I
P
-
V
T
D
S
K
S
D
G
I
I
Y
L
T
I
S
-------------
K
D
N
I
C
Q
F
S
D
E
K
G
-
E
---
Q
I
D
I
---
N
S
Q
F
N
S
F
----
E
Y
D
G
I
S
-
F
H
L
K
N
M
--
R
E
D
K
--------------------------------------------------------------------------------------------
37
Fugue
54.22
18%
-45
- C5 -
2LGE
-
?
A:
[1-129]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
D
D
D
E
P
G
G
K
G
A
M
Y
E
V
T
I
E
Q
S
G
DFRSFI
K
---
S
V
V
V
V
-----
A
N
G
T
Q
L
K
D
G
A
-----
T
G
E
S
L
-
A
-------------------
S
-
P
V
I
---
L
S
-
D
E
E
L
A
V
E
K
V
T
L
S
T
T
G
-----
K
A
I
E
F
A
-
V
S
G
G
V
--
V
D
G
E
D
G
-
V
---
V
N
E
P
M
Q
W
V
V
T
V
-
Y
K
----
N
G
K
E
I
E
-
K
K
S
L
V
F
--
R
D
G
K
E
I
S
T
D
D
L
N
L
Y
Y
N--------------------------------------------------------------------------------
6
PsiBlast_PDB
50.60
32%
-43
- C7 -
3TI3
1
?
A:
[165-208]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
S
N
-
G
Q
A
S
Y
K
I
F
R
I
E
K
G
-
K
---
I
V
K
S
V
E
M
N
A
P
N
Y
H
Y
----
E
-------
E
C
S
C
Y
--
P
D
S
S
E
I
T
-----------------------------------------------------------------------------------------
9
PsiBlast_PDB
50.58
32%
-46
- C7 -
3TI6
2
?
A:
[165-208]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
S
N
-
G
Q
A
S
Y
K
I
F
R
I
E
K
G
-
K
---
I
V
K
S
V
E
M
N
A
P
N
Y
H
Y
----
E
-------
E
C
S
C
Y
--
P
D
S
S
E
I
T
-----------------------------------------------------------------------------------------
8
PsiBlast_PDB
50.50
32%
-42
- C7 -
3TI5
1
?
A:
[165-208]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
S
N
-
G
Q
A
S
Y
K
I
F
R
I
E
K
G
-
K
---
I
V
K
S
V
E
M
N
A
P
N
Y
H
Y
----
E
-------
E
C
S
C
Y
--
P
D
S
S
E
I
T
-----------------------------------------------------------------------------------------
13
PsiBlast_PDB
50.40
32%
-54
- C7 -
4B7M
-
?
A:
[246-289]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
S
D
-
G
Q
A
S
Y
K
I
F
R
I
E
K
G
-
K
---
I
V
K
S
V
E
M
N
A
P
N
Y
H
Y
----
E
-------
E
C
S
C
Y
--
P
D
S
S
E
I
T
-----------------------------------------------------------------------------------------
10
PsiBlast_PDB
50.40
32%
-42
- C7 -
4B7R
1
?
A:
[164-207]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
S
N
-
G
Q
A
S
Y
K
I
F
R
I
E
K
G
-
K
---
I
V
K
S
V
E
M
N
A
P
N
Y
H
Y
----
E
-------
E
C
S
C
Y
--
P
D
S
S
E
I
T
-----------------------------------------------------------------------------------------
11
PsiBlast_PDB
50.22
32%
-51
- C7 -
4QNP
-
?
A:
[165-208]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
S
N
-
G
Q
A
S
Y
K
I
F
R
I
E
K
G
-
K
---
I
V
K
S
V
E
M
N
A
P
N
Y
H
Y
----
E
-------
E
C
S
C
Y
--
P
D
S
S
E
I
T
-----------------------------------------------------------------------------------------
4
PsiBlast_PDB
50.00
32%
-40
- C7 -
4B7Q
1
?
A:
[246-289]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
S
N
-
G
Q
A
S
Y
K
I
F
R
I
E
K
G
-
K
---
I
V
K
S
V
E
M
N
A
P
N
Y
H
Y
----
E
-------
E
C
S
C
Y
--
P
D
S
S
E
I
T
-----------------------------------------------------------------------------------------
7
PsiBlast_PDB
49.56
32%
-42
- C7 -
3TI4
1
?
A:
[165-208]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
S
N
-
G
Q
A
S
Y
K
I
F
R
I
E
K
G
-
K
---
I
V
K
S
V
E
M
N
A
P
N
Y
H
Y
----
E
-------
E
C
S
C
Y
--
P
D
S
S
E
I
T
-----------------------------------------------------------------------------------------
14
PsiBlast_PDB
49.05
32%
-52
- C7 -
4B7N
1
?
A:
[246-289]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
S
D
-
G
Q
A
S
Y
K
I
F
R
I
E
K
G
-
K
---
I
V
K
S
V
E
M
N
A
P
N
Y
H
Y
----
E
-------
E
C
S
C
Y
--
P
D
S
S
E
I
T
-----------------------------------------------------------------------------------------
5
PsiBlast_PDB
49.00
32%
-46
- C7 -
3NSS
2
?
A:
[165-208]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
S
N
-
G
Q
A
S
Y
K
I
F
R
I
E
K
G
-
K
---
I
V
K
S
V
E
M
N
A
P
N
Y
H
Y
----
E
-------
E
C
S
C
Y
--
P
D
S
S
E
I
T
-----------------------------------------------------------------------------------------
12
PsiBlast_PDB
48.35
32%
-40
- C7 -
4B7J
1
?
A:
[246-289]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
S
D
-
G
Q
A
S
Y
K
I
F
R
I
E
K
G
-
K
---
I
V
K
S
V
E
M
N
A
P
N
Y
H
Y
----
E
-------
E
C
S
C
Y
--
P
D
S
S
E
I
T
-----------------------------------------------------------------------------------------
39
Fugue
46.32
29%
-60
* C5 *
4A94
4
MCPI_NERVS
C:
[3-53]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
P
D
D
R
--
P
C
I
N
P
-----
G
R
C
P
L
V
-
P
D
A
T
C
T
F
V
C
K
A
A
D
-
N
DFG
Y
E
C
Q
H
V
W
T
F
E
G
--------------
Q
R
V
G
C
Y
--
A
-----------------------------------------------------------------------------------------------
36
Fugue
45.30
21%
-24
- C5 -
2R2C
-
?
A:
[36-180]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
S
Y
K
T
W
D
V
P
I
A
K
I
N
I
F
A
V
A
E
Y
------
T
DTQ
K
I
K
V
T
-----
V
K
G
K
I
L
E
G
N
T
L
P
---------
K
-------------------
S
M
V
Q
V
---
Y
L
-
L
E
D
--
K
N
H
V
L
R
G
A
V
N
GIWG
E
E
F
V
N
L
K
-
D
Y
L
Y
T
Y
A
V
E
P
L
S
G
M
S
---
F
V
-------
A
E
N
Y
S
----
I
V
A
F
V
Y
D
V
Q
T
F
E
V
--
Y
D
V
V
H
V
K
I
N
P
Q
S------------------------------------------------------------------------------------