@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo0123: (2016-03-12 )
MDYVIIQSMDKEVEEILTDIDYGSFSYDYEKNTSRAISFTVNKTKQNAAIFDLVGNEAILTYQGQQFVIKKCTPKSIGGTLSKQITAQHICYTVQDHVQYNVKSGRKKYSIQTVLEFALQDNVLGFSYEIQGSFPLVELEDLGNKNGLELVNLCLEEFGAILFADNKKLYFYDEKSWYVKTEKQFRYLYNTEEVSVDTNTDNLKTEIKCYGKQKENADKLTGDNKYMAVVTYTSPNEAIYGKRMANAKSDDKITNNDDLLIFAKKQILDVPETALTISYKGKEPVSERDVWYFIHEPMGFETEVKVTKIKSSHPWSKKFQEIGFSNSRRDMVRIQTQIANQVKKASVDTNKINSFSSIAMNAYDSRILTEVVGVVDGD
Atome Classification :
(20 SA)
-----------......-...10........20----------------........30...-..-.-..----.40.........50--........60.-----.-.--.---...---.70..-.-...-..80-...-----......90........100.........110.......120-.-.---.-....-130-..--.---.-.--..-..140.---......150.......160-...-.-.-..170......-.180....-----...190.......200...-----------...----.210........-220.......-230--........240.......250.-------..---...-.260.......--270.........280------..------.....290.....-------..300-.......310..-.-....320.......330------.-..-.....340..-.---....350..----------...------.----.360..--.....370......--------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-----------M
D
Y
V
I
I
-
Q
S
M
D
K
E
V
E
E
I
L
T
DID----------------YGS
F
S
Y
D
YE-KNT-
S
R
-
A
-
I
S
----
F
T
-VNKTKQN
A
A
I
F
--
D
LVGN
E
A
I
L
T
Y-----Q-G--
Q
---
Q
F
V
---
I
K
KCT-P-KSI-G
G
T
--
L
S
K
-----
Q
I
T
A
Q
H
I
C
Y
T
V
Q
D
H
V
Q
Y
--NVKSG
R
K
K
Y
S
I
Q
T
V
L
E
F
A
LQDN-V-
L
---
G
-
F
S
Y
E
-I---QG--S---F-P--
L
V
-
E
L
E
DLG---NKN
G
L
E
L
V
N
L
C
L
E
EFG
A
I
L
-
F
AD-N-
K
-
K
L
Y
F
YDE
K
S
W
Y
-
V
K
T
E
K
Q
F
R
-----
Y
L
YN
T
E
E
V
S
VDTNTDN
L
K
T
-----------
E
I
K
----
C
Y-GKQKENADK-LTGDN
K
Y
M
A
V
-
V
T
---YTSPNE
A
I
Y
G
K
RMANAKSDDKI-------TN---ND
D
-
L
L
I
F
A
K
K
QILD--V--PE
T
A
L
T
I
S
YKGK------EP------VSER
D
V
W
Y
F
I
HEP-------MGFE
T
-
E
V
K
V
T
K
IKSSH
P
-
W
-
S
K
K
F
Q
EIGFSNSRR
D
M
-------
V
-
R
I
-
Q
T
Q
I
A
N
Q
V
K
K-A---SVDTNKIN
S
----------
F
S
S
------
I
----
A
M
N
A
Y
D
--
S
R
I
L
T
E
V
V
G
VVDGD--------------------------------
14
Fugue
91.35
24%
-41
- C5 -
3GS9
-
?
A:
[3-339]
------------
S
D
I
I
V
-
A
D
F
W
N
N
E
E
I
L
----------------------
T
D
F
D
D
S
F
E
-
S
W
T
-
E
N
-
E
M
W
S
----
I
E
-
F
V
A
Q
T
C
Y
------
S
F
L
D
Y
E
S
S
V
Y
F
-----
R
-
G
--
Q
---
E
F
V
---
V
K
Q
L
S
-
H
-
D
A
----
T
--
L
S
K
-----
D
I
R
A
P
H
I
Y
Y
T
C
Q
D
G
R
Q
D
--
D
A
I
T
G
S
F
--
T
L
E
Q
C
L
T
H
I
F
T
D
N
-
R
G
F
---
S
-
W
E
I
I
-
D
---
P
S
--
N
---
I
-
L
--
E
V
-
Q
Q
E
N
F
G
---
N
N
N
Y
L
T
L
I
D
Q
L
L
D
D
Y
G
V
V
V
-
I
P
D
-
N
-
R
-
H
L
V
F
P
R
E
I
Y
---
G
A
K
T
E
N
F
I
-----
R
Y
Y
N
T
D
E
A
S
F
D
I
D
T
L
S
L
T
I
-----------
G
Y
G
----
V
D
-
S
N
G
N
N
Y
F
S
P
-
I
T
Y
T
S
---------------
P
E
V
E
W
G
I
R
W
Q
E
P
V
S
D
E
R
Y
-------
T
V
---
A
G
N
M
Q
R
--
R
L
L
E
L
Q
D
--
Y
--
P
A
T
T
G
S
V
-----------
I
L
------
E
C
E
G
D
Y
V
L
F
I
Y
E
P
-------
L
G
I
D
Y
-
D
V
Q
I
V
A
Y
Y
P
F
------
T
I
A
P
E
I
T
L
S
N
N
S
I
V
S
-------
I
M
A
Q
-
L
A
V
L
G
-------------------------------------------------------------------------------------------------
5
HHSearch
66.90
12%
-35
- C5 -
3D37
3
?
A:
[24-340]
---------------------------------------------------
R
Y
D
I
D
S
D
-
F
L
I
P
A
D
-
S
-
F
D
----
F
V
-
I
G
R
-----------
P
D
L
S
G
E
S
C
E
V
V
I
---
D
-
G
--
Q
IV
M
T
G
I
---
I
G
S
Q
R
-
H
-
G
K
S
-
K
G
S
--
R
E
L
-----
S
L
S
G
R
D
L
A
G
F
L
V
D
C
S
A
P
--
Q
L
N
--
V
K
G
M
T
V
L
D
A
A
K
K
L
A
A
P
W
-------
P
Q
I
K
A
V
V
L
---
K
A
EN
N
---
P
-
A
--
L
G
-
K
I
D
I
E
P
---
G
E
T
V
W
Q
A
L
T
H
I
A
N
S
V
G
L
H
P
-
W
L
E
P
D
-
G
-
T
L
V
V
G
G
A
D
-
Y
S
-
S
P
P
V
A
T
L
C
W
S
RTD
S
R
C
N
I
E
R
M
D
I
E
W
D
T
D
N
R
F
S
-----------
E
V
T
----
F
L
-
A
Q
S
H
G
-----------
H
D
L
K
-
W
V
---
Y
K
D
P
T
M
T
L
H
R
P
K
---
T
V
V
V
S
---------
D
N
---
L
A
A
-
L
Q
K
Q
A
K
K
Q
L
A
D
--
W
R
L
E
G
F
T
L
T
I
T
V
G
G
H
KTRDG-
V
L
------
W
Q
P
G
L
R
V
H
V
I
D
D
E
-------
H
G
I
D
A
-
V
F
F
L
M
G
R
R
F
M
L
S
R
M
-
D
G
T
Q
T
E
L
R
L
K
E
D
G
I
--------------------------------------------------------------------------------------------------------------------
20
Fugue
66.05
21%
-9
- C2 -
4R2F
1
?
A:
[38-431]
----G
A
I
K
F
W
D
M
P
W
A
T
--
P
A
Y
N
D
A
A
K
K
I
A
E
G
F
S
GAN
S
K
A
T
Y
Q
I
I
Q
WNN
F
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Q
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F
S
S
A
I
A
-
S
K
T
-
G
P
-
A
-
V
S
T
G
G
G
F
Q
-
A
F
Q
F
E
E
Q
G
Q
I
A
YA
D
K
V
I
E
K
L
K
S
N
G
-----
Q
-
F
--
D
---
D
F
L
---
P
G
V
V
E
-
P
F
K
T
S
-
K
G
Y
V
A
V
P
W
-----
Q
L
D
I
R
P
L
W
Y
R
K
S
L
F
E
K
A
--
G
V
G
V
P
T
D
W
A
S
L
L
E
A
G
K
K
L
K
G
V
G
-
A
-
V
---
G
-
F
A
T
-------
G
--
S
---
G
-
A
----------
G
---
N
N
I
G
N
H
L
M
I
M
M
M
L
N
N
G
G
G
V
-
F
T
K
-
D
-
G
-
E
L
D
V
L
N
D
R
N
V
E
A
V
E
F
L
L
E
L
V
-----
S
N
G
V
I
D
P
A
A
V
S
Y
T
T
D
N
L
N
A
-----------
Q
W
K
D
SKA
A
Y
-
G
M
L
T
L
G
V
P
E
-
R
V
G
D
T
S
G
D
I
V
-
V
A
-----
S
P
I
A
G
P
H
G
D
K
A
---------------------------------
A
L
I
--
F
--
P
N
N
I
M
M
Y
T
N
T
P
S
------
Q
E
------
A
S
E
E
F
V
V
Y
Y
L
G
K
L
-----------
K
-
E
L
W
Q
Q
K
L
M
N
A
L
P
-
V
-
F
K
S
I
T
E
M
P
E
F
T
A
D
P
N
N
-------
V
-
K
I
-
V
N
E
Y
V
P
I
A
K
T
F
A
---
S
Q
G
T
A
L
S
A
N
----------
L
A
A
------
L
D
GG
Q
A
L
N
Q
F
T
--
Q
T
V
L
T
---
G
K
T
D
A
K
S
A
L
T
A
F
D
T
G
L
K
S
V
LKK----------------
22
Fugue
65.24
16%
-17
- C4 -
4TXD
1
?
A:
[21-369]
-----------
K
R
D
V
L
A
-
E
L
G
L
G
D
L
R
P
Y
L
R
S
I
G
---------------------------
D
K
-
D
R
-
I
-
F
P
--------
K
A
H
R
I
E
V
V
F
L
--
V
R
A
A
N
Y
L
L
L
R
T
-----
E
-
G
--
A
---
G
T
I
---
N
M
T
T
L
-
E
-
Y
S
G
-
G
A
M
--
E
V
P
-----
V
I
Q
P
Q
K
L
M
A
V
T
R
R
Q
M
L
Q
--
L
L
R
E
Y
R
D
S
--
L
D
E
V
S
K
R
W
L
V
Q
E
-
V
-
I
---
G
-
K
A
K
D
-
L
-------
G
---
F
-
K
--
K
V
-
S
E
E
W
N
C
---
T
I
Q
G
M
D
G
F
C
P
H
C
T
I
F
G
A
A
L
-
T
E
Q
-
H
-
N
-
E
K
F
--
G
G
L
S
I
G
-
I
K
T
R
V
R
F
D
-----
P
A
F
A
T
Q
R
-
R
I
T
P
E
T
H
N
-------------------------
K
V
T
E
G
H
L
S
-
M
T
G
Q
A
L
F
----------------------------
S
E
V
-------
H
V
---
E
P
G
-
T
V
F
I
G
R
A
E
L
V
D
--
L
--
T
E
P
E
L
V
A
T
L
Y
S
L
------
A
T
------
L
R
E
L
G
G
R
S
G
I
Y
G
-----------
T
V
-
R
V
E
I
L
G
V
K
A
G
K
Y
-
A
-
S
T
T
A
Y
D
L
A
A
E
N
A
G
K
G
Y
-------
E
-
E
V
-
K
K
N
L
K
E
R
L
E
K
-
L
G
F
T
P
V
D
N
S
K
L
L
A
A
V
DHKDPNG
L
F
K
D
------
L
----
W
R
S
S
I
D
F
A
E
K
M
V
K
W
V
E
E
L
K
G
G
G
--------------------------------
16
Fugue
59.24
16%
-28
* C3 *
3G8Q
2
CDAT8_METKA
A:
[1-278]
-----------
M
K
V
S
L
A
G
Q
T
V
D
--
V
K
K
I
L
N
E
I
P
----------------------------------------------
K
R
T
V
T
A
A
L
L
--
E
---------------
G
-
G
--
E
---
I
V
A
---
V
E
E
A
D
-
D
-
E
H
A
-
E
R
K
--
L
V
R
-----
R
H
D
V
E
G
K
V
V
F
V
T
A
R
P
C
L
--
Y
C
A
R
E
L
A
E
A
G
V
A
G
V
V
Y
L
G
R
G
R
G
-
L
-
G
---
P
-
Y
Y
L
A
-
R
---
S
G
------------
V
-
E
V
V
E
V
H
---
P
D
E
P
L
G
Y
D
P
V
--
D
R
L
D
V
L
L
T
F
G
G
-
N
-
P
-
Y
L
---
T
E
E
D
V
A
-
A
R
V
Y
C
L
L
T
-----
G
R
G
F
D
A
D
I
A
P
A
P
E
N
L
S
G
R
V
-----------
E
I
M
----
V
T
R
G
D
P
D
E
A
V
E
L
-
L
K
E
E
L
P
V
F
R
I
-
R
R
---
F
L
-----
I
S
G
E
F
-------
D
R
D
-------
E
L
---
R
E
R
-
I
L
E
D
I
E
P
R
I
L
D
----------------------------------------------------
P
F
A
V
-
R
A
R
I
A
R
A
G
A
--------------
F
S
S
S
R
E
A
E
-------
V
-
F
I
-
G
D
V
L
T
S
V
G
R
E
-
V
---
N
L
N
D
P
R
--------------
T
V
------
V
----
T
V
D
V
L
G
--
P
R
V
---
S
V
G
V
E
K
R
---------------------------------
7
HHSearch
57.16
11%
-38
- C5 -
1WRU
-
BP44_BPMU
A:
[18-336]
--------------------------------------------------
T
S
V
S
V
T
R
S
-
I
E
S
-
V
A
G
Y
-
F
E
----
L
G
-
V
N
V
P
P
--
G
T
D
L
--
S
G
L
A
P
G
K
K
F
T
L
E
I
---
G
-
G
--
Q
IV
C
T
G
Y
---
I
D
S
R
R
-
R
-
Q
M
T
-
A
D
S
--
M
K
I
-----
T
V
A
G
R
D
K
T
A
D
L
I
D
C
A
A
V
Y
S
G
G
Q
--
W
K
N
R
T
L
E
Q
I
A
R
D
L
C
A
P
Y
-------
G
-
V
T
V
R
-
W
---
E
L
--
S
DKE
S
S
A
--
A
F
P
G
F
T
L
D
H
---
S
E
T
V
Y
E
A
L
V
R
A
S
R
A
R
G
V
L
M
-
T
S
N
-
A
A
G
-
E
L
V
F
S
R
---
A
A
-
S
T
A
T
D
E
L
V
-----
L
G
E
N
L
L
T
L
D
F
E
E
D
F
R
D
R
F
S
-----------
E
Y
T
----
V
K
-------------------
S
R
K
G
T
---
A
T
D
S
D
V
T
R
Y
R
---
P
M
I
I
I
A
D
S
K
-------
I
T
---
A
K
D
-
A
Q
A
R
A
L
R
E
Q
R
R
R
L
A
--
K
S
I
T
F
E
A
E
I
D
G
W
TRKDG-
Q
L
------
W
M
P
N
L
L
V
T
I
D
A
S
K
-------
Y
A
I
K
T
T
E
L
L
V
S
K
V
T
L
I
L
N
-
D
Q
D
G
L
K
T
R
V
S
L
A
P
R
----------------------------------------------------------------------------------------------------------------------
6
HHSearch
55.98
10%
-38
* C5 *
3CDD
-
?
A:
[54-342]
-------------------------------------------------------------------------------------------
P
I
K
Q
G
Q
A
C
T
V
D
I
---
G
-
G
E-
R
V
I
-
T
G
Y
---
V
D
D
W
V
-
P
-
S
Y
D
-
E
S
T
--
I
T
I
-----
S
V
S
G
R
D
K
T
A
D
L
V
D
C
S
I
D
YP
S
G
Q
--
F
N
N
Q
T
L
T
Q
I
A
D
I
V
C
K
P
F
-------
G
-
I
K
V
I
-
V
---
N
T
--
D
---
V
-
G
EP
F
Q
-
R
I
Q
I
E
Q
---
G
E
T
P
H
E
L
L
A
R
L
A
K
Q
R
G
V
L
L
-
T
S
D
-
T
F
G
-
N
L
V
I
T
R
---
A
S
K
T
K
A
G
V
S
L
I
-----
L
G
D
N
V
K
A
A
R
G
R
F
S
W
R
Q
R
F
S
-----------
K
F
T
----
I
K
-
A
A
-----------------
K
-
A
D
---
V
T
D
S
E
I
G
R
Y
R
P
L
---
I
I
V
N
E
E
V
-------
T
----
A
E
G
-
A
A
K
R
G
Q
W
E
R
Q
R
S
I
G
--
K
S
N
M
A
E
Y
T
V
T
G
W
------
R
I
PQTGKL
W
N
I
N
T
L
V
P
V
I
D
E
I
-------
M
G
L
D
E
-
E
-
L
I
A
S
I
L
F
S
E
D
-
D
-
A
G
R
L
A
V
I
S
V
V
R
P
D
A
M
-------------------------------------------------------------------------------------------------------------------
21
Fugue
53.46
9%
-3
- C5 -
1WRU
-
BP44_BPMU
A:
[3-346]
------------
N
T
V
T
L
-
R
A
D
G
R
L
F
T
------
G
----------------
W
T
S
V
S
V
T
R
S
I
E
S
V
-
A
G
-
Y
-
F
E
----
L
G
-
V
N
V
P
P
G
T
D
L
S
G
--
L
A
P
G
K
K
F
T
L
E
I
-----
G
-
G
--
Q
---
I
V
C
T
G
Y
I
D
S
R
R
-
R
-
Q
M
T
-
A
D
S
--
M
K
I
-----
T
V
A
G
R
D
K
T
A
D
L
I
D
C
A
A
V
--
Y
S
G
G
Q
W
K
N
R
T
L
E
Q
I
A
R
D
L
C
A
P
Y
-
G
-
V
---
T
-
V
R
W
E
-
L
SDK
E
S
--
S
---
A
-
A
--
F
P
-
G
F
T
L
D
H
---
S
E
T
V
Y
E
A
L
V
R
A
S
R
A
R
G
V
L
M
-
T
S
N
-
A
-
A
G
E
L
V
F
S
R
A
A
S
----
T
A
T
D
E
L
V
-----
L
G
E
N
L
L
T
L
D
F
E
E
D
F
R
D
R
F
S
-----------
E
Y
T
----
V
K
-
S
R
K
G
T
A
T
D
S
-
D
V
T
R
Y
R
P
M
I
I
-
I
A
---
D
S
K
I
T
A
K
D
A
Q
A
R
A
L
R
E
Q
R
R
R
L
A
-------
K
S
-------------------------
I
T
F
E
A
E
I
D
G
W
------
T
R
------
K
D
--------
G
Q
L
-------
W
M
P
N
L
-
L
V
T
I
D
A
S
K
Y
A
I
K
---
T
T
E
L
L
V
S
K
V
T
L
I
L
N
D
Q
-------
D
-
G
L
-
K
T
R
V
S
L
A
P
R
E
-
G
---
F
L
V
P
V
E
S
D
-------------------------------------------------------------------------------
8
HHSearch
51.91
12%
-61
- C5 -
2P5Z
-
?
X:
[29-270]
--------------------------------------------------
L
T
F
E
G
R
E
Q
-
L
S
T
-
P
F
-
R
-
Y
D
----
I
Q
-
F
T
S
S
D
K
A
I
A
P
E
--
S
V
L
M
Q
D
G
A
F
S
L
-----
T
A-AL
R
TL-
H
G
V
---
I
T
G
F
K
-
H
-
L
S
S
S
Q
D
E
--
A
R
Y
-----
E
V
R
L
E
P
R
M
A
L
L
T
R
S
R
Q
N
---
A
I
--
Y
Q
N
Q
T
V
P
Q
I
V
E
K
I
L
R
E
R
H
Q
-
M
RGQ
D
-
F
V
F
N
-
L
---
K
S
--
E
---
Y
-
P
--
A
R
-
E
Q
V
M
Q
Y
---
G
E
D
D
L
T
F
V
S
R
L
L
S
E
V
G
I
W
F
-
R
F
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
Fugue
51.39
12%
-24
- C3 -
2GGS
1
?
A:
[1-273]
-----------
M
R
T
L
I
T
-
G
A
S
G
Q
L
G
I
E
L
S
R
L
L
---------------------------
S
E
R
-
H
E
-
V
-
I
K
----
V
Y
-
N
S
S
E
I
Q
G
G
Y
K
L
--
D
L
T
D
F
P
R
L
E
D
F
-----
I
-
I
--
K
---
K
-----------------------
R
P
-----
D
V
I
I
N
A
A
A
M
T
D
V
D
K
C
E
I
--
E
-----------------------------------------------------
K
-
E
K
A
Y
K
I
---
N
A
E
A
V
R
H
I
V
R
A
G
K
V
I
D
S
Y
I
-
V
H
I
-
S
-
T
-
D
Y
V
F
D
G
E
K
G
N
Y
--------------------------
K
E
E
D
I
P
N
-----------
P
I
N
----
Y
Y
-
G
L
S
K
L
L
G
E
T
-
F
A
L
Q
D
D
S
L
I
I
-
R
T
S
GI
F
R
N
K
G
F
P
I
Y
V
Y
K
T
L
K
E
G
K
T
V
F
A
F
K
G
Y
Y
S
P
I
S
---
A
R
K
-
L
A
S
A
I
L
E
L
L
E
L
--
R
--
K
T
G
I
I
H
V
A
G
E
R
---------------
I
S
R
F
E
L
A
L
K
I
K
E
K
-------
F
N
L
P
G
-
E
V
K
E
V
D
E
V
R
G
W
I
-----------------------------------
A
K
R
P
Y
D
-
S
---
S
L
D
S
S
R
A
R
K
----------
I
L
S
------
T
----
D
F
Y
T
L
D
--
L
D
G
M
V
V
----------------------------------------
23
Fugue
51.17
19%
-16
- C6 -
4Q2E
5
CDSA_THEMA
A:
[29-290]
I
T
A
S
V
V
A
P
F
V
V
L
C
F
V
S
Y
-
E
S
L
I
G
L
V
S
A
I
L
I
L
A
G
----------------
Y
E
L
I
T
L
--
E
-
M
K
E
-
R
D
-
A
-
R
F
----
F
Y
-
V
I
L
L
A
L
Y
P
V
L
Y
--
G
L
V
F
E
E
--------------------------------------------
P
-----
T
Q
P
L
S
I
L
F
I
T
G
V
V
F
S
L
I
--
T
D
K
D
P
S
Q
V
F
K
T
V
A
A
F
S
I
A
L
I
Y
V
-
T
-
F
---
F
-
L
S
---------------
F
-
F
--
L
P
-
I
Y
R
D
F
G
---
A
A
N
A
L
-
L
V
L
T
S
T
W
V
F
D
S
F
A
-
Y
F
T
-
G
-
L
-
K
F
--------------------------
G
R
T
R
I
S
-----------------------
P
----
R
Y
-
S
P
R
K
S
L
E
G
V
-
I
G
G
---
F
L
G
V
-
V
I
---
Y
T
F
L
Y
R
L
V
V
N
D
L
L
S
V
N
------------------------
V
I
C
F
R
T
F
L
P
--
F
--
A
A
T
V
A
I
M
D
T
F
G
D
------
I
F
------
E
C
A
L
K
R
H
Y
----------------------------------------
G
V
K
D
S
G
K
T
L
--------------------
P
G
-
H
---
G
G
M
L
D
R
I
D
G
----------
L
L
F
------
V
----
A
P
V
S
Y
I
--
V
F
K
I
L
E
--
G
V
V
R
----------------------------------
19
Fugue
50.16
12%
-9
* C6 *
2A9F
1
?
A:
[3-388]
-----------
L
K
N
Q
L
--
G
Q
L
A
L
E
Q
A
K
T
F
G
G
K
L
----------------
E
V
Q
P
K
V
D
I
K
-
T
K
H
-
D
L
-
S
-
I
A
----
Y
T
-
P
G
V
A
S
V
S
S
A
I
A
--
K
D
K
T
L
A
Y
D
L
T
T
-----
K
-
K
--
N
---
T
V
A
---
V
I
S
D
G
-
T
-
A
V
L
-
G
L
G
--
D
I
G
-----
P
E
A
A
M
P
V
M
E
G
K
A
A
L
F
K
A
--
F
A
G
V
----
D
A
I
P
I
V
L
D
T
K
D
T
E
E
-
I
-
I
---
S
-
I
V
K
A
-
L
---
A
P
--
T
---
F
-
G
--
G
I
-
N
L
E
D
I
S
---
A
P
R
C
F
E
I
E
Q
R
L
I
K
E
C
H
I
P
V
-
F
H
D
-
D
-
Q
-
H
G
T
A
I
V
V
L
A
A
I
-
F
N
S
L
K
L
----------------
L
K
K
S
L
D
E
V
S
I
-----------
V
V
N
----
G
G
-
G
S
A
G
L
S
I
T
R
-
K
L
L
A
A
G
A
T
K
V
-
T
V
---
V
D
K
F
G
-
I
I
N
E
Q
E
A
A
Q
L
A
P
D
I
A
K
-------
V
T
---
N
R
E
-
F
K
S
G
T
L
E
D
A
L
E
--
G
--
A
D
I
F
I
G
V
S
A
P
G
V
LK
A
E
W
I
S
K
------
M
A
A
R
P
V
I
F
A
M
A
N
P
IPEIY
P
D
E
A
L
E
A
-
G
A
Y
I
V
G
T
G
R
S
D
F
-
P
-
N
Q
I
N
N
V
L
A
F
P
G
I
F
R
G
A
-------
L
-
D
A
R
A
K
T
I
T
V
E
M
Q
I
-
A
---
A
A
K
G
I
A
S
L
V
----------
P
D
D
ALSTTN
I
----
I
P
D
A
F
K
--
E
G
V
A
E
I
V
A
K
S
V
R
S
V
VL------------------------------
15
Fugue
49.74
11%
13
* C4 *
4QIQ
1
XYLE_ECOLI
A:
[7-470]
------------
S
Y
I
F
S
-
I
T
L
V
A
T
L
G
G
L
L
F
G
Y
D
----------------
T
A
V
I
S
G
T
V
E
-
S
L
N
-
T
V
-
F
-
V
A
----
P
Q
N
L
S
E
S
A
A
N
S
L
L
G
--
F
C
V
A
S
A
L
I
G
C
I
-----
I
-
G
--
G
---
A
L
G
---
G
Y
C
S
N
-
R
-
F
G
R
-
R
D
S
--
L
K
I
A
A
V
L
F
F
I
S
G
V
G
S
A
W
P
E
L
G
F
T
S
I
--
N
P
D
N
T
V
P
V
Y
L
A
G
Y
V
P
E
F
V
I
Y
R
I
-
I
-
G
---
G
-
I
G
V
G
-
L
---
A
S
--
M
---
L
-
S
--
P
M
-
Y
I
A
E
L
A
PAH
I
R
G
K
L
V
S
F
N
Q
F
A
I
I
F
G
Q
L
L
-
V
Y
C
-
V
-
N
-
Y
F
I
A
R
S
G
D
A
S
W
-
L
N
T
D
-
G
W
R
-----
Y
M
F
A
S
E
C
I
P
A
L
L
F
L
M
L
L
Y
T
VPESPRWLMT
L
A
T
Q
----
A
V
-
Q
E
I
K
H
S
L
D
R
L
L
M
F
G
V
G
V
I
V
I
-
G
V
---
M
L
S
I
F
Q
Q
F
V
G
I
N
V
V
L
Y
Y
A
P
E
V
F
-------
K
T
L
GA
S
T
D
-
I
A
L
L
Q
T
I
I
V
G
V
--
I
--
N
L
T
F
T
V
L
A
I
M
T
V
------
D
K
------
F
G
R
K
P
L
Q
I
I
G
A
L
G
-------
M
A
I
G
M
-
F
S
L
G
T
A
F
Y
T
Q
A
P
-
G
-
I
V
A
L
L
S
M
L
F
Y
V
A
A
F
A
M
SWGP
V
C
W
V
-
L
L
-
S
E
I
F
P
N
A
I
R
G
-
K
---
A
L
A
I
A
V
A
A
Q
----------
W
L
A
------
N
----
Y
F
V
S
W
T
--
F
P
M
M
D
K
N
S
W
L
V
A
H
F
HNGF
S
Y
W
I
Y
G
C
M
G
V
L
A
A
L
F
M
W
KFVPETKGKTL
9
HHSearch
37.45
8%
14
- C5 -
2KZ4
-
?
A:
[55-108]
-------------------------------------------------------------
A
-
I
G
-
T
-
V
R
----
I
W
-
I
R
Y
R
---------
K
D
I
N
A
T
S
R
I
K
V
STGPL
A
-
G
--
R
---
V
L
N
---
I
I
G
Q
P
L
P
-
D
A
A
---
R
--
T
R
L
-----
E
I
L
C
R
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
29.02
10%
18
- C5 -
3CPF
-
IF5A1_HUMAN
A:
[10-51]
------------------------------------------------------------------------------------------
S
A
L
R
K
N
G
F
V
V
L
-----
K
-
G
--
R
---
P
C
K
---
I
V
E
M
S
-
T
-
S
K
T
---
H
--
A
K
V
-----
H
L
V
G
I
D
I
F
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
19.44
31%
62
* C7 *
2KEW
-
YNDB_BACSU
A:
[74-118]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
---
S
-
F
E
W
D
-
T
---
E
G
--
W
---
V
-
V
--
T
F
-
Q
L
E
D
L
G
---
E
K
T
G
F
T
L
I
H
S
G
W
K
E
P
N
Q
V
I
-
G
K
A
-
N
-
E
-
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
16.07
46%
189
- C1 -
4P42
-
ESYT2_HUMAN
A:
[387-416]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
R
Y
K
T
N
------
E
P
------
V
W
E
E
N
F
T
F
F
I
H
N
P
-------
K
R
Q
D
L
-
E
V
E
V
---------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
15.76
31%
81
- C7 -
2KTE
-
YNDB_BACSU
A:
[74-118]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
---
S
-
F
E
W
D
-
T
---
E
G
--
W
---
V
-
V
--
T
F
-
Q
L
E
D
L
G
---
E
K
T
G
F
T
L
I
H
S
G
W
K
E
P
N
E
V
I
-
G
K
A
-
N
-
E
-
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
14.03
7%
166
- C5 -
2E6Z
-
SPT5H_HUMAN
A:
[419-446]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
------
F
Q
P
G
D
N
V
E
V
C
E
G
E
-------
L
I
-
N
L
-
Q
G
K
I
L
S
V
D
G
N
---------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
13.46
14%
198
- C5 -
1XNE
-
?
A:
[33-60]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
D
------
I
K
R
G
D
K
I
I
F
N
D
L
------------
I
-
P
A
E
V
V
E
V
K
K
Y
E
T
-
F
-----------------------------------------------------------------------------------------------------------------------------------