@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo1548: (2016-03-26 )
MFGFGNKDIGIDLGTANTLVYMKGKGIVLREPSVVAMKKDTQEIVAVGSDAKNMIGRTPGNIVAIRPMKDGVIADYDTTAAMMKYYIQKAGKSVNASKPRVMICVPSGITGVEKRAVIDATRQAGAKDAFTIEEPFAAAIGAGLPVGEPTGSMVVDIGGGTTEVAVISLGGIVTSRSVRTAGDDLDEVIINYIRKKYNLLIGDRTAEAIKMEIGSASPKGLDLSPFSIRGRDLVTGLPKTIEITPEEISEALADTVAAIIDAVKGTLENTPPELSADIMDKGIVLTGGGALLRNLDTVISEETKMPVIIADEPLDCVAIGTGKALENMDMYKRKKMN
Atome Classification :
(21 SA)
---------------------------------------------.........10........20....-..-.---------.---------.---------30--------........--40-----------.------....---....50........60.--------------------.--------------------------------------..--------------------...-------------------------------.-------70-------------..-------...------------...80........90........100.......110.......120...--------------.....130.......140..-----.-.---.-------.--.150...-....160.......-170.-------.---------.-.-----.--...----.180--.........190.......---200-----------.-------------.-------------.......210....-..-.220..-...---------...230-....----....--240......---.250...------.-...260.......270.......280.......290.......300--..-.-..--------------------..-310.......320......-.330.....---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---------------------------------------------MFGFGNK
D
I
G
I
D
LGTA
N
T
L
V
-
Y
M
KG-
K
G
-
I
---------
V
---------
L
---------RE--------P
S
V
V
A
MKK--D------------
T
------
Q
E
I
V
---AVGS
D
A
K
N
M
IGRTPG
N
I
--------------------
V
--------------------------------------
A
I
--------------------
R
PM-------------------------------K-------D
G
-------------
V
I-------ADY------------
D
T
T
A
A
M
M
K
Y
Y
I
Q
K
AGKSVNASK
P
R
V
M
I
CVPSGITGV
E
K
R
A
V
I
D
A
T
-
R
QA--------------GAKD
A
F
T
IEE
P
F
A
A
A
IGAGL-----P-V---G-------E--PTG
S
M
V
V
-
D
IGGG
T
T
E
V
A
V
I
S
L
-
G
--
G
-------
I
---------
V
-T-----S--RSV----RT----AGD
D
L
D
E
V
I
I
N
Y
I
R
K
K
Y
N
L
---
L
-------------I-------------G-------------DRT
A
E
A
I
K
M
EIGSA-SP-KG-LDL-SPF---------SIRG
R
--
D
L
VT----GLP
K
--
T
I
E
I
T
P
E
E
I
---
S
E
A
L
A
D
T
------
V
-
A
A
I
I
D
A
V
K
G
T
LENTPPE
L
S
A
D
I
MDK
G
I
V
L
TG
G
G
A
L
L
R
N
L
D
T
V
ISEE--TK-M-
P
V
--------------------
I
I
-ADEPL
D
C
V
A
IGTG
K
A
L
E
N
M
-
D
M
Y
K
RKKMN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
98.55
56%
-97
- C2 -
2WUS
-
?
A:
[3-331]
--------------------------------------------------
R
K
D
I
G
I
D
L
G
T
A
N
T
L
V
-
F
L
R
G
-
K
G
-
I
---------
V
---------
V
---------
N
E
--------
P
S
V
I
A
I
D
S
--
T
------------
T
------
G
E
I
L
---
K
V
G
L
E
A
K
N
M
I
G
K
T
P
A
T
I
--------------------
K
--------------------------------------
A
I
--------------------
R
P
M
-------------------------------
R
-------
D
G
-------------
V
I
-------
A
D
Y
------------
T
V
A
L
V
M
L
R
Y
F
I
N
K
A
K
G
G
M
N
L
F
K
P
R
V
V
I
G
V
P
I
G
I
T
D
V
E
R
R
A
I
L
D
A
G
-
L
E
A
--------------
G
A
S
K
V
F
L
I
E
E
P
M
A
A
A
I
G
S
N
L
-----
N
-
V
---
E
-------
E
--
P
S
G
N
M
V
V
-
D
I
G
G
G
T
T
E
V
A
V
I
S
L
-
G
--
S
-------
I
---------
V
-
T
-----
W
--
E
S
I
----
R
I
----
A
G
D
E
M
D
E
A
I
V
Q
Y
V
R
E
T
Y
R
V
---
A
-------------
I
-------------
G
-------------
E
R
T
A
E
R
V
K
I
E
I
G
N
V
-
F
P
S
K
E
-
N
D
E
-
L
E
T
---------
T
V
S
G
I
--
D
L
S
T
----
G
L
P
R
--
K
L
T
L
K
G
G
E
V
---
R
E
A
L
R
S
V
------
V
-
V
A
I
V
E
S
V
R
T
T
L
E
K
T
P
P
E
L
V
S
D
I
I
E
R
G
I
F
L
T
G
G
G
S
L
L
R
G
L
D
T
L
L
Q
K
E
--
T
G
-
I
-
S
V
--------------------
I
R
-
S
E
E
P
L
T
A
V
A
K
G
A
G
M
V
L
D
K
V
-
N
I
L
K
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
98.54
56%
-95
- C2 -
1JCF
-
?
A:
[3-331]
--------------------------------------------------
R
K
D
I
G
I
D
L
G
T
A
N
T
L
V
-
F
L
R
G
-
K
G
-
I
---------
V
---------
V
---------
N
E
--------
P
S
V
I
A
I
D
S
--
T
------------
T
------
G
E
I
L
---
K
V
G
L
E
A
K
N
M
I
G
K
T
P
A
T
I
--------------------
K
--------------------------------------
A
I
--------------------
R
P
M
-------------------------------
R
-------
D
G
-------------
V
I
-------
A
D
Y
------------
T
V
A
L
V
M
L
R
Y
F
I
N
K
A
K
G
G
M
N
L
F
K
P
R
V
V
I
G
V
P
I
G
I
T
D
V
E
R
R
A
I
L
D
A
G
-
L
E
A
--------------
G
A
S
K
V
F
L
I
E
E
P
M
A
A
A
I
G
S
N
L
-----
N
-
V
---
E
-------
E
--
P
S
G
N
M
V
V
-
D
I
G
G
G
T
T
E
V
A
V
I
S
L
-
G
--
S
-------
I
---------
V
-
T
-----
W
--
E
S
I
----
R
I
----
A
G
D
E
M
D
E
A
I
V
Q
Y
V
R
E
T
Y
R
V
---
A
-------------
I
-------------
G
-------------
E
R
T
A
E
R
V
K
I
E
I
G
N
V
-
F
P
S
K
E
-
N
D
E
-
L
E
T
---------
T
V
S
G
I
--
D
L
S
T
----
G
L
P
R
--
K
L
T
L
K
G
G
E
V
---
R
E
A
L
R
S
V
------
V
-
V
A
I
V
E
S
V
R
T
T
L
E
K
T
P
P
E
L
V
S
D
I
I
E
R
G
I
F
L
T
G
G
G
S
L
L
R
G
L
D
T
L
L
Q
K
E
--
T
G
-
I
-
S
V
--------------------
I
R
-
S
E
E
P
L
T
A
V
A
K
G
A
G
M
V
L
D
K
V
-
N
I
L
K
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
98.00
56%
-96
- C2 -
1JCG
2
?
A:
[3-331]
--------------------------------------------------
R
K
D
I
G
I
D
L
G
T
A
N
T
L
V
-
F
L
R
G
-
K
G
-
I
---------
V
---------
V
---------
N
E
--------
P
S
V
I
A
I
D
S
--
T
------------
T
------
G
E
I
L
---
K
V
G
L
E
A
K
N
M
I
G
K
T
P
A
T
I
--------------------
K
--------------------------------------
A
I
--------------------
R
P
M
-------------------------------
R
-------
D
G
-------------
V
I
-------
A
D
Y
------------
T
V
A
L
V
M
L
R
Y
F
I
N
K
A
K
G
G
M
N
L
F
K
P
R
V
V
I
G
V
P
I
G
I
T
D
V
E
R
R
A
I
L
D
A
G
-
L
E
A
--------------
G
A
S
K
V
F
L
I
E
E
P
M
A
A
A
I
G
S
N
L
-----
N
-
V
---
E
-------
E
--
P
S
G
N
M
V
V
-
D
I
G
G
G
T
T
E
V
A
V
I
S
L
-
G
--
S
-------
I
---------
V
-
T
-----
W
--
E
S
I
----
R
I
----
A
G
D
E
M
D
E
A
I
V
Q
Y
V
R
E
T
Y
R
V
---
A
-------------
I
-------------
G
-------------
E
R
T
A
E
R
V
K
I
E
I
G
N
V
-
F
P
S
K
E
-
N
D
E
-
L
E
T
---------
T
V
S
G
I
--
D
L
S
T
----
G
L
P
R
--
K
L
T
L
K
G
G
E
V
---
R
E
A
L
R
S
V
------
V
-
V
A
I
V
E
S
V
R
T
T
L
E
K
T
P
P
E
L
V
S
D
I
I
E
R
G
I
F
L
T
G
G
G
S
L
L
R
G
L
D
T
L
L
Q
K
E
--
T
G
-
I
-
S
V
--------------------
I
R
-
S
E
E
P
L
T
A
V
A
K
G
A
G
M
V
L
D
K
V
-
N
I
L
K
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
97.00
56%
-93
- C2 -
4CZM
2
?
B:
[3-332]
--------------------------------------------------
S
N
D
I
A
I
D
L
G
T
A
N
T
L
I
-
Y
Q
K
G
-
K
G
-
I
---------
V
---------
L
---------
N
E
--------
P
S
V
V
A
L
R
N
VG
G
------------
R
------
K
V
V
H
---
A
V
G
I
E
A
K
Q
M
L
G
R
T
P
G
H
M
--------------------
E
--------------------------------------
A
I
--------------------
R
P
M
-------------------------------
R
-------
D
G
-------------
V
I
-------
A
D
F
------------
E
V
A
E
E
M
I
K
Y
F
I
R
K
V
H
N
R
K
G
S
G
N
P
K
V
I
V
C
V
P
S
G
A
T
A
V
E
R
R
A
I
N
D
S
C
-
L
N
A
--------------
G
A
R
R
V
G
L
I
D
E
P
M
A
A
A
I
G
A
G
L
-----
P
-
I
---
H
-------
E
--
P
T
G
S
M
V
V
-
D
I
G
G
G
T
T
E
V
A
V
L
S
L
-
S
--
G
-------
I
---------
V
-
Y
-----
S
--
R
S
V
----
R
V
----
G
G
D
K
M
D
E
A
I
I
S
Y
M
R
R
H
H
N
L
---
L
-------------
I
-------------
G
-------------
E
T
T
A
E
R
I
K
K
E
I
G
T
A
R
A
P
-
A
D
-
G
E
G
-
L
S
I
---------
D
V
K
G
R
--
D
L
M
Q
----
G
V
P
R
--
E
V
R
I
S
E
K
Q
A
---
A
D
A
L
A
E
P
------
V
-
G
Q
I
V
E
A
V
K
V
A
L
E
A
T
P
P
E
L
A
D
D
I
A
D
K
G
I
M
L
T
G
G
G
A
L
L
R
G
L
D
A
E
I
R
D
H
--
T
G
-
L
-
P
V
--------------------
T
V
-
A
D
D
P
L
S
C
V
A
L
G
C
G
K
V
L
E
H
P
-
K
W
M
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
96.69
56%
-96
- C2 -
4CZJ
2
?
B:
[5-327]
----------------------------------------------------
D
I
A
I
D
L
G
T
A
N
T
L
I
-
Y
Q
K
G
-
K
G
-
I
---------
V
---------
L
---------
N
E
--------
P
S
V
V
A
L
R
N
V
G
G
------------
R
------
K
V
V
H
---
A
V
G
I
E
A
K
Q
M
L
G
R
T
P
G
H
M
--------------------
E
--------------------------------------
A
I
--------------------
R
P
M
-------------------------------
R
-------
D
G
-------------
V
I
-------
A
D
F
------------
E
V
A
E
E
M
I
K
Y
F
I
R
K
V
H
N
------
P
K
V
I
V
C
V
P
S
G
A
T
A
V
E
R
R
A
I
N
D
S
C
-
L
N
A
--------------
G
A
R
R
V
G
L
I
D
E
P
M
A
A
A
I
G
A
G
L
-----
P
-
I
---
H
-------
E
--
P
T
G
S
M
V
V
-
D
I
G
G
G
T
T
E
V
A
V
L
S
L
-
S
--
G
-------
I
---------
V
-
Y
-----
S
--
R
S
V
----
R
V
----
G
G
D
K
M
D
E
A
I
I
S
Y
M
R
R
H
H
N
L
---
L
-------------
I
-------------
G
-------------
E
T
T
A
E
R
I
K
K
E
I
G
T
A
R
A
P
-
A
D
-
G
E
G
-
L
S
I
---------
D
V
K
G
R
--
D
L
M
Q
----
G
V
P
R
--
E
V
R
I
S
E
K
Q
A
---
A
D
A
L
A
E
P
------
V
-
G
Q
I
V
E
A
V
K
V
A
L
E
A
T
P
P
E
L
A
S
D
I
A
D
K
G
I
M
L
T
G
G
G
A
L
L
R
G
L
D
A
E
I
R
D
H
--
T
G
-
L
-
P
V
--------------------
T
V
-
A
D
D
P
L
S
C
V
A
L
G
C
G
K
V
L
E
H
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
96.21
56%
-91
- C2 -
4CZE
1
?
A:
[3-326]
--------------------------------------------------
S
N
D
I
A
I
D
L
G
T
A
N
T
L
I
-
Y
Q
K
G
-
K
G
-
I
---------
V
---------
L
---------
N
E
--------
P
S
V
V
A
L
R
N
V
G
G
------------
R
------
K
V
V
H
---
A
V
G
I
E
A
K
Q
M
L
G
R
T
P
G
H
M
--------------------
E
--------------------------------------
A
I
--------------------
R
P
M
-------------------------------
R
-------
D
G
-------------
V
I
-------
A
D
F
------------
E
V
A
E
E
M
I
K
Y
F
I
R
K
V
H
N
R
K
G
F
V
N
P
K
V
I
V
C
V
P
S
G
A
T
A
V
E
R
R
A
I
N
D
S
C
-
L
N
A
--------------
G
A
R
R
V
G
L
I
D
E
P
M
A
A
A
I
G
A
G
L
-----
P
-
I
---
H
-------
E
--
P
T
G
S
M
V
V
-
D
I
G
G
G
T
T
E
V
A
V
L
S
L
-
S
--
G
-------
I
---------
V
-
Y
-----
S
--
R
S
V
----
R
V
----
G
G
D
K
M
D
E
A
I
I
S
Y
M
R
R
H
H
N
L
---
L
-------------
I
-------------
G
-------------
E
T
T
A
E
R
I
K
K
E
I
G
T
A
R
A
P
-----
E
G
-
L
S
I
---------
D
V
K
G
R
--
D
L
M
Q
----
G
V
P
R
--
E
V
R
I
S
E
K
Q
A
---
A
D
A
L
A
E
P
------
V
-
G
Q
I
V
E
A
V
K
V
A
L
E
A
T
P
P
E
L
A
S
D
I
A
D
K
G
I
M
L
T
G
G
G
A
L
L
R
G
L
D
A
E
I
R
D
H
--
T
G
-
L
-
P
V
--------------------
T
V
-
A
D
D
P
L
S
C
V
A
L
G
C
G
K
V
L
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
95.92
56%
-91
- C2 -
4CZL
2
?
A:
[3-332]
--------------------------------------------------
S
N
D
I
A
I
D
L
G
T
A
N
T
L
I
-
Y
Q
K
G
-
K
G
-
I
---------
V
---------
L
---------
N
E
--------
P
S
V
V
A
L
R
N
V
G
G
------------
R
------
K
V
V
H
---
A
V
G
I
E
A
K
Q
M
L
------
M
--------------------
E
--------------------------------------
A
I
--------------------
R
P
M
-------------------------------
R
-------
D
G
-------------
V
I
-------
A
D
F
------------
E
V
A
E
E
M
I
K
Y
F
I
R
K
V
H
N
R
K
G
S
G
N
P
K
V
I
V
C
V
P
S
G
A
T
A
V
E
R
R
A
I
N
D
S
C
-
L
N
A
--------------
G
A
R
R
V
G
L
I
D
E
P
M
A
A
A
I
G
A
G
L
-----
P
-
I
---
H
-------
E
--
P
T
G
S
M
V
V
-
D
I
G
G
G
T
T
E
V
A
V
L
S
L
-
S
--
G
-------
I
---------
V
-
Y
-----
S
--
R
S
V
----
R
V
----
G
G
D
K
M
D
E
A
I
I
S
Y
M
R
R
H
H
N
L
---
L
-------------
I
-------------
G
-------------
E
T
T
A
E
R
I
K
K
E
I
G
T
A
R
A
P
-
A
D
-
G
E
G
-
L
S
I
---------
D
V
K
G
R
--
D
L
M
Q
----
G
V
P
R
--
E
V
R
I
S
E
K
Q
A
---
A
D
A
L
A
E
P
------
V
-
G
Q
I
V
E
A
V
K
V
A
L
E
A
T
P
P
E
L
A
D
D
I
A
D
K
G
I
M
L
T
G
G
G
A
L
L
R
G
L
D
A
E
I
R
D
H
--
T
G
-
L
-
P
V
--------------------
T
V
-
A
D
D
P
L
S
C
V
A
L
G
C
G
K
V
L
E
H
P
-
K
W
M
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
HHSearch
73.62
28%
-69
- C2 -
2V7Y
2
DNAK_GEOKA
A:
[2-351]
--------------------------------------------------
S
K
I
I
G
I
D
L
G
T
T
N
S
C
V
-
A
V
L
E
-
G
G
E
V
K
V
I
P
N
PEG-
N
---------
R
---------
T
T
--------
P
S
V
V
A
F
K
N
-----------------------
G
E
R
---
L
V
G
E
V
A
K
R
Q
A
I
T
N
P
N
T
I
--------------------
I
--------------------------------------
S
I
--------------------
K
R
H
MGTD
Y
K
V
E
I
----------------------
E
-------
G
K
-------------
Q
Y
-------
T
P
Q
------------
E
I
S
A
I
I
L
Q
Y
L
K
S
Y
A
E
D
Y
L
G
E
P
V
T
R
A
V
I
T
V
P
A
Y
F
N
D
A
Q
R
Q
A
T
K
D
A
G
-
R
I
A
--------------
G
L
E
V
E
R
I
I
N
E
P
T
A
A
A
L
A
Y
G
L
-----
D
-
K
---
E
-------
E
--
D
Q
T
I
L
V
Y
-
D
L
G
G
G
T
F
D
V
S
I
L
E
L
-
G
--
D
-------
G
---------
V
-
F
E
V
K
A
T
A
--
G
D
N
----
H
L
----
G
G
D
D
F
D
Q
V
I
I
D
Y
L
V
N
Q
F
K
Q
---
E
-------------
H
GIDLSKD
K
M
A
L
Q
R
L
-------------
K
D
A
A
E
K
A
K
K
E
L
S
G
V
-
T
Q
--------
T
Q
I
---------
S
L
P
F
I
SA
N
E
N
G
----
P
L
H
L
--
E
M
T
L
T
R
A
K
F
---
E
E
L
S
A
H
L
------
V
-
E
R
T
M
G
P
V
R
Q
A
L
Q
D
A
G
L
T
P
---
A
D
I
D
K
V
I
L
V
G
G
S
T
R
I
P
A
V
Q
E
A
I
K
R
E
--
L
G
-
K
-
E
P
--------------------
H
K
-
G
V
N
P
D
E
V
V
A
I
G
A
A
I
Q
G
G
V
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
HHSearch
72.47
56%
-12
- C2 -
1JCE
-
?
A:
[4-330]
---------------------------------------------------
K
D
I
G
I
D
L
G
T
A
N
T
L
V
-
F
L
R
G
-
K
G
-
I
---------
V
---------
V
---------
N
E
--------
P
S
V
I
A
I
D
S
--
T
------------
T
------
G
E
I
L
---
K
V
G
L
E
A
K
N
M
I
G
K
T
P
A
T
I
--------------------
K
--------------------------------------
A
I
--------------------
R
P
M
-------------------------------
R
-------
D
G
-------------
V
I
-------
A
D
Y
------------
T
V
A
L
V
M
L
R
Y
F
I
N
K
A
K
G
G
M
N
L
F
K
P
R
V
V
I
G
V
P
I
G
I
T
D
V
E
R
R
A
I
L
D
A
G
-
L
E
A
--------------
G
A
S
K
V
F
L
I
E
E
P
M
A
A
A
I
G
S
N
L
-----
N
-
V
---
E
-------
E
--
P
S
G
N
M
V
V
-
D
I
G
G
G
T
T
E
V
A
V
I
S
L
-
G
--
S
-------
I
---------
V
-
T
-----
W
--
E
S
I
----
R
I
----
A
G
D
E
M
D
E
A
I
V
Q
Y
V
R
E
T
Y
R
V
---
A
-------------
I
-------------
G
-------------
E
R
T
A
E
R
V
K
I
E
I
G
N
V
-
F
P
-
S
K
E
N
D
E
-
L
E
T
---------
T
V
S
G
I
--
D
L
S
T
----
G
L
P
R
--
K
L
T
L
K
G
G
E
V
---
R
E
A
L
R
S
V
------
V
-
V
A
I
V
E
S
V
R
T
T
L
E
K
T
P
P
E
L
V
S
D
I
I
E
R
G
I
F
L
T
G
G
G
S
L
L
R
G
L
D
T
L
L
Q
K
E
--
T
G
-
I
-
S
V
--------------------
I
R
-
S
E
E
P
L
T
A
V
A
K
G
A
G
M
V
L
D
K
V
-
N
I
L
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
72.30
55%
-13
- C2 -
1JCE
-
?
A:
[4-331]
---------------------------------------------------
K
D
I
G
I
D
L
G
T
A
N
T
L
V
-
F
L
R
G
-
K
G
-
I
---------
V
---------
V
---------
N
E
--------
P
S
V
I
A
I
D
S
--
T
------------
T
------
G
E
I
L
---
K
V
G
L
E
A
K
N
M
I
G
K
T
P
A
T
I
--------------------
K
--------------------------------------
A
I
--------------------
R
P
M
-------------------------------
R
-------
D
G
-------------
V
I
-------
A
D
Y
------------
T
V
A
L
V
M
L
R
Y
F
I
N
K
A
K
G
G
M
N
L
F
K
P
R
V
V
I
G
V
P
I
G
I
T
D
V
E
R
R
A
I
L
D
A
G
-
L
E
A
--------------
G
A
S
K
V
F
L
I
E
E
P
M
A
A
A
I
G
S
N
L
-----
N
-
V
---
E
-------
E
--
P
S
G
N
M
V
V
-
D
I
G
G
G
T
T
E
V
A
V
I
S
L
-
G
--
S
-------
I
---------
V
-
T
-----
W
--
E
S
I
----
R
I
----
A
G
D
E
M
D
E
A
I
V
Q
Y
V
R
E
T
Y
R
V
---
A
-------------
I
-------------
G
-------------
E
R
T
A
E
R
V
K
I
E
I
G
N
V
-
F
P
S
K
E
-
N
D
E
-
L
E
T
---------
T
V
S
G
I
--
D
L
S
T
----
G
L
P
R
--
K
L
T
L
K
G
G
E
V
---
R
E
A
L
R
S
V
------
V
-
V
A
I
V
E
S
V
R
T
T
L
E
K
T
P
P
E
L
V
S
D
I
I
E
R
G
I
F
L
T
G
G
G
S
L
L
R
G
L
D
T
L
L
Q
K
E
--
T
G
-
I
-
S
V
--------------------
I
R
-
S
E
E
P
L
T
A
V
A
K
G
A
G
M
V
L
D
K
V
-
N
I
L
K
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
67.78
25%
-75
- C2 -
1DKG
-
DNAK_ECOLI
D:
[3-349]
---------------------------------------------------
K
I
I
G
I
D
L
G
T
T
N
S
C
V
A
I
M
D
G
-
T
T
-
P
---------
R
---------
V
---------
L
E
NAEGDRTT
P
S
I
I
A
Y
T
Q
--
D
------------
G
------
E
T
L
V
-----
G
Q
P
A
K
R
Q
A
V
T
N
P
Q
N
T
LFAIKRLIGRRFQDEEVQRD
V
--------------------------------------
S
I
--------------------
M
P
F
-------------------------------
K
IIAADNG
D
A
-------------
W
V
EVKGQKM
A
P
P
------------
Q
I
S
A
E
V
L
K
K
M
K
K
T
A
E
D
Y
L
G
E
P
V
T
E
A
V
I
T
V
P
A
Y
F
N
D
A
Q
R
Q
A
T
K
D
A
G
-
R
I
A
--------------
G
L
E
V
K
R
I
I
N
E
P
T
A
A
A
L
A
Y
G
L
-----
D
-
K
-----------
T
--
G
N
R
T
I
A
V
Y
D
L
G
G
G
T
F
D
I
S
I
I
E
I
-
D
-----------EKTFEVL--
A
-
T
-----
N
--
G
D
T
----
H
L
----
G
G
E
D
F
D
S
R
L
I
N
Y
L
V
E
E
F
K
K
---
D
-------------
Q
-------------
G
IDLRNDPLAMQRL
K
E
A
A
E
K
A
K
I
E
L
S
S
A
-
Q
Q
-
T
D
-
V
N
L
-
P
Y
I
---------
T
A
D
A
------
T
----
G
-
P
K
HM
N
I
K
V
T
R
A
K
L
---
E
S
L
V
E
D
L
------
V
-
N
R
S
I
E
L
L
K
V
A
L
Q
D
A
G
L
S
V
S
-
D
I
D
D
--
V
I
L
V
G
G
-------------
Q
--
T
R
-
M
-
P
M
--------------------
V
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
HHSearch
67.43
20%
-69
- C2 -
3D2F
4
?
A:
[2-391]
--------------------------------------------------
S
T
P
F
G
L
D
L
G
N
N
N
S
V
L
-
A
V
A
R
-
N
R
-
G
I
D
I
V
V
N
EVS
N
---------
R
---------
S
T
--------
P
S
V
V
G
F
G
P
-----------------------
K
N
R
---
Y
L
G
E
T
G
K
N
K
Q
T
S
N
I
K
N
T
--------------------
V
--------------------------------------
A
N
LKRIIGLDYHHPD
F
E
Q
E
S
K
H
F
T
S
-------------------------------
K
L
V
E
L
D--
D
K
K
T
G
A
E
V
R
F
AG
E
K
H
V
F
-------
S
A
T
------------
Q
L
A
A
M
F
I
D
K
V
K
D
T
V
K
Q
D
T
K
A
N
I
T
D
V
C
I
A
V
P
P
W
Y
T
E
E
Q
R
Y
N
I
A
D
A
A
-
R
I
A
--------------
G
L
N
P
V
R
I
V
N
D
V
T
A
A
G
V
S
Y
G
I
-----
F
-
K
---
T
DLPEGEE
K
--
P
R
I
V
A
F
V
-
D
I
G
H
S
S
Y
T
C
S
I
M
A
F
-
K
--
K
G
Q
-----
L
K
V
-------
L
G
T
-----
A
--
C
D
K
----
H
F
----
G
G
R
D
F
D
L
A
I
T
E
H
F
A
D
E
F
K
T
---
K
YKIDIREN
P
K
A
Y
N
R
-------------
I
-------------
L
T
A
A
E
K
L
K
K
V
L
S
A
N
-
T
N
--------
A
P
F
---------
S
V
E
----
S
V
M
N
----
D
V
D
V
--
S
S
Q
L
S
R
E
E
L
---
E
E
L
V
K
P
L
------
L
-
E
R
V
T
E
P
V
T
K
A
L
A
Q
A
K
L
S
A
---
E
E
V
D
F
V
E
I
I
G
G
T
T
R
I
P
T
L
K
Q
S
I
S
E
A
--
F
G
-
K
-
P
L
--------------------
S
T
-
T
L
N
Q
D
E
A
I
A
K
G
A
A
F
I
C
A
I
H
-
S
P
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
HHSearch
66.84
18%
-65
- C2 -
1K8K
-
ARP3_BOVIN
A:
[3-388]
------------------------------------------------
G
R
L
P
A
C
V
V
D
C
G
T
G
Y
T
K
L
-
G
Y
A
G
-
N
T
E
P
---------
Q
---------
F
---------
I
I
--------
P
S
C
I
A
I
K
E
----------------VMKGVD
D
L
D
F
---
F
I
G
D
E
A
I
E
K
-----
P
T
Y
--------------------
A
--------------------------------------
T
K
--------------------
W
P
I
-------------------------------
R
-------
H
G
-------------
I
V
-------
E
D
W
------------
D
L
M
E
R
F
M
E
Q
V
I
F
K
Y
L
R
A
-
E
P
E
D
H
Y
F
L
L
T
E
P
P
L
N
T
P
E
N
R
E
Y
T
A
E
I
M
F
E
S
F
--------------
N
V
P
G
L
Y
I
A
V
Q
A
V
L
A
L
A
A
S
W
T
-----
S
-
R
QVG
E
-------
R
--
T
L
T
G
T
V
I
-
D
S
G
D
G
V
T
H
V
I
P
V
A
E
-
G
--
Y
-------
V
---------
I
-
G
-----
S
C
I
K
H
I
----
P
I
----
A
G
R
D
I
T
Y
F
I
Q
Q
L
L
R
D
R
E
V
G
IPP
E
-------------
Q
-------------
S
-------------
L
E
T
A
K
A
V
K
E
R
Y
S
Y
V
-
C
P
-
D
L
-
V
K
E
F
N
K
Y
D
T
DGSKW
I
K
Q
Y
T
G
I
--
N
A
I
S
----
K
K
E
F
--
S
I
D
V
G
Y
E
R
F
LGP
E
I
F
F
H
P
E
FANPDF
T
-
Q
P
I
S
E
V
V
D
E
V
I
Q
N
C
P
I
D
V
R
R
P
L
Y
K
N
-
I
V
L
S
G
G
S
T
M
F
R
D
F
G
R
R
L
Q
R
D
--
L
K
-
R
-
T
V
D
A
R
L
K
L
S
E
E
L
SKPK
P
I
D
V
Q
V
I
T
-
H
H
M
Q
R
Y
A
V
W
F
G
G
S
M
L
A
S
T
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
HHSearch
66.75
22%
-78
- C2 -
3I33
3
HSP72_HUMAN
A:
[23-401]
--------------------------------------------------
M
P
A
I
G
I
D
L
G
T
T
Y
S
C
V
-
G
V
F
Q
-
H
G
K
V
E
I
I
A
N
DQG-
N
---------
R
---------
T
T
--------
P
S
Y
V
A
F
T
D
-----------------------
T
E
R
---
L
I
G
D
A
A
K
N
Q
V
A
M
N
P
T
N
T
--------------------
I
--------------------------------------
F
D
AKRLIG--------------
R
K
F
ED
A
T
V
Q
S
D
M
K
H
WP
F
R
V
V
S
E
GG
K
P
K
V
Q
V
E
Y
KG
E
-------
T
K
-------------
T
F
-------
F
P
E
------------
E
I
S
S
M
V
L
T
K
M
K
E
I
A
E
A
Y
L
G
G
K
V
H
S
A
V
I
T
V
P
A
Y
F
N
D
S
Q
R
Q
A
T
K
D
A
G
-
T
I
T
--------------
G
L
N
V
L
R
I
I
N
E
P
T
A
A
A
I
A
Y
G
L
-----
D
-
K
---
K
GCAG---
G
--
E
K
N
V
L
I
F
-
D
L
G
G
G
T
F
D
V
S
I
L
T
I
-
E
--
D
GI-----
F
---------
E
-
V
K
S
T
--
A
--
G
D
T
----
H
L
----
G
G
E
D
F
D
N
R
M
V
S
H
L
A
E
E
F
K
R
---
K
HKKDIGPN
K
R
A
V
R
R
-------------
L
-------------
R
T
A
C
E
R
A
K
R
T
L
S
S
S
-
T
Q
--------
A
S
I
---------
E
I
D
S
----
L
Y
E
----
G
V
D
F
--
Y
T
S
I
T
R
A
R
F
---
E
E
L
N
A
D
L
------
F
-
R
G
T
L
E
P
V
E
K
A
L
R
D
A
K
L
D
K
---
G
Q
I
Q
E
I
V
L
V
G
G
S
T
R
I
P
K
I
Q
K
L
L
Q
D
F
--
F
N
G
K
-
E
L
--------------------
N
K
-
S
I
N
P
D
E
A
V
A
Y
G
A
A
V
Q
A
A
I
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
51
Fugue
66.42
26%
-80
- C2 -
1DKG
-
DNAK_ECOLI
D:
[3-383]
---------------------------------------------------
K
I
I
G
I
D
L
G
T
T
N
S
C
V
-
A
I
M
D
-
G
T
-
T
---------
P
---------
R
VLENAEGDR
T
T
--------
P
S
I
I
A
Y
T
Q
--
D
-----------------------GET
L
V
G
Q
P
A
K
R
Q
A
V
T
N
P
Q
N
T
--------------------
L
FAIKRLIGRRFQDEEVQRDVSIMPFKIIAADNGDAWVE
V
----------------------
K
G
----------------------------------------
Q
-------------
K
M
-------
A
P
P
------------
Q
I
S
A
E
V
L
K
K
M
K
K
T
A
E
D
Y
L
G
E
P
V
T
E
A
V
I
T
V
P
A
Y
F
N
D
A
Q
R
Q
A
T
K
D
A
G
-
R
I
A
--------------
G
L
E
V
K
R
I
I
N
E
P
T
A
A
A
L
A
Y
G
L
-----
D
K----
T
-------
G
--
N
R
T
I
A
V
Y
-
D
L
G
G
G
T
F
D
I
S
I
I
E
I
-
D
--
E
KTFEVLA------------
T
-----
N
--
G
D
T
----
H
L
----
G
G
E
D
F
D
S
R
L
I
N
Y
L
V
E
E
F
K
K
---
D
-------------
Q
-------------
G
IDLRNDPLAMQRL
K
E
A
A
E
K
A
K
I
E
L
S
S
----------
A
-
Q
Q
T
---------
D
V
N
L
P
--
Y
I
T
A
DATG
P
K
H
M
--
N
I
K
V
T
R
A
K
L
---
E
S
L
V
E
D
L
------
V
N-
R
S
I
E
L
L
K
V
A
L
Q
D
A
G
--
L
S
V
S
D
I
D
-
D
V
I
L
V
G
G
Q
T
R
M
P
M
V
Q
K
K
V
A
E
F
FG---
K
-
E
P
--------------------
R
K
-
D
V
N
P
D
E
A
V
A
I
G
A
A
V
Q
G
G
V
L
T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
53
Fugue
64.52
18%
-46
- C2 -
2QXL
3
HSP7F_YEAST
A:
[2-656]
T
P
F
G
L
DLGNN
N
S
V
L
A
V
A
R
NR
G
I
D
I
V
V
N
EVSNRSTPS
V
V
G
F
G
PK
N
R
Y
L
G
E
T
G
K
N
-
K
Q
T
S
N
I
K
N
T
V
A
-
N
L
K
R
I
I
G
-
L
---------
D
---------
Y
---------
H
H
--------
P
D
F
E
Q
E
S
K
--
H
------------
F
------
T
S
K
L
---
V
E
L
D
D
K
K
T
G
A
E
V
R
F
A
G
--------------------------------------------------------------------------------------------------------------------
E
-------
K
H
-------------
V
F
-------
S
A
T
------------
Q
L
A
A
M
F
I
D
K
V
K
D
T
V
K
Q
D
T
K
A
N
I
T
D
V
C
I
A
V
P
P
W
Y
T
E
E
Q
R
Y
N
I
A
D
A
A
-
R
I
A
--------------
G
L
N
P
V
R
I
V
N
D
V
T
A
A
G
V
S
Y
G
I
F
KTDL
P
-
E
---
G
-------
E
E
K
P
R
I
V
A
F
V
-
D
I
G
H
S
S
Y
T
C
S
I
M
A
F
K
K
--
G
-------
Q
---------
L
-
K
-----
V
--
L
G
T
----
A
C
DKHF
G
G
R
D
F
D
L
A
I
T
E
H
F
A
D
E
F
K
T
---
K
-------------
Y
-------------
K
IDIREN-------
P
K
A
Y
N
R
I
L
T
A
A
E
K
L
-
K
K
-
V
L
-
S
A
N
-
T
N
A
---------
P
F
S
V
E
--
S
V
M
N
----
D
V
D
V
--
S
S
Q
L
S
R
E
E
L
---
E
E
L
V
K
P
L
------
L
-
E
R
V
T
E
P
V
T
K
A
L
A
Q
A
--
K
L
S
A
E
E
V
D
-
F
V
E
I
I
G
G
T
T
R
I
P
T
L
K
Q
S
I
S
E
A
--
F
G
-
K
-
P
L
--------------------
S
T
-
T
L
N
Q
D
E
A
I
A
K
G
A
A
F
I
C
A
I
-----
H
S
R
P
F
K
F
E
D
I
H
P
Y
S
V
S
Y
S
W
DKQVEDED
H
M
E
V
FPAGSSFP
S
T
K
L
I
T
L
N
R
T
G
D
F
S
M
A
A
S
Y
TDITQLPPNTPEQI
A
N
W
E
I
TD
S
V
P
V
K
L
K
L
R
CDPSG
L
H
T
I
E
E
A
Y
T
I
E
DK
T
V
K
K
D
D
L
T
I
V
A
H
T
FGLD
A
K
K
L
N
E
L
I
E
K
E
N
E
M
L
A
Q
D
K
L
V
A
E
T
E
D
R
K
N
T
L
E
E
Y
I
Y
T
L
R
G
K
L
E
EEYAPFAS
D
A
E
K
T
K
L
Q
G
M
L
N
K
A
E
E
W
L
Y
DEGFDSI
K
A
K
Y
I
A
K
Y
E
E
L
A
S
L
G
N
I
I
R
G
R
Y
L
A
K
E
E
E
K
K
Q
A
I
R
S
K
Q
34
HHSearch
64.29
24%
-73
- C2 -
3QFU
3
GRP78_YEAST
A:
[16-393]
------------------------------------------------
N
Y
G
T
V
I
G
I
D
L
G
T
T
Y
S
C
V
-
A
V
M
K
-
N
G
K
T
E
I
L
A
N
EQG-
N
---------
R
---------
I
T
--------
P
S
Y
V
A
F
T
D
-----------------------
D
E
R
---
L
I
G
D
A
A
K
N
Q
V
A
A
N
P
Q
N
T
--------------------
I
--------------------------------------
F
D
IKRLIGLKYND
R
S
V
Q
K
D
I
K
H
L
P
F
N
V
V
N
K
DG
K
P
A
V
E
V
S
V
KG--------------
E
-------
K
K
-------------
V
F
-------
T
P
E
------------
E
I
S
G
M
I
L
G
K
M
K
Q
I
A
E
D
Y
L
G
T
K
V
T
H
A
V
V
T
V
P
A
Y
F
N
D
A
Q
R
Q
A
T
K
D
A
G
-
T
I
A
--------------
G
L
N
V
L
R
I
V
N
E
P
T
A
A
A
I
A
Y
G
L
-----
D
-
K
S--
D
-------
K
--
E
H
Q
I
I
V
Y
-
D
L
G
G
G
T
F
D
V
S
L
L
S
I
-
E
--
N
-------
G
---------
V
-
F
EVQ
A
T
S
--
G
D
T
----
H
L
----
G
G
E
D
F
D
Y
K
I
V
R
Q
L
I
K
A
F
K
K
---
K
-------------
H
GIDVSDN
N
K
A
L
A
K
L
-------------
K
R
E
A
E
K
A
K
R
A
L
S
S
Q
-
M
S
--------
T
R
I
---------
E
I
D
S
----
F
V
D
----
G
I
D
L
--
S
E
T
L
T
R
A
K
F
---
E
E
L
N
L
D
L
------
F
-
K
K
T
L
K
P
V
E
K
V
L
Q
D
S
G
L
E
K
---
K
D
V
D
D
I
V
L
V
G
G
S
T
R
I
P
K
V
Q
Q
L
L
E
S
Y
--
F
D
G
K
-
K
A
--------------------
S
K
-
G
I
N
P
D
E
A
V
A
Y
G
A
A
V
Q
A
G
V
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
63.82
25%
-80
- C2 -
2KHO
-
DNAK_ECOLI
A:
[5-349]
-----------------------------------------------------
I
G
I
D
L
G
T
T
N
S
C
V
A
I
M
D
G
-
T
T
-
P
---------
R
---------
V
---------
L
E
N
AEGDRTT
P
S
I
I
A
Y
T
Q
--
D
------------
G
------
E
T
L
V
-----
G
Q
P
A
K
R
Q
A
V
T
N
P
Q
N
T
LFAIKRLIGRRFQD
E
E
V
Q
R
D
V
--------------------------------------
S
I
--------------------
M
P
F
-------------------------------
K
I
I
A
A
DNG
D
A
-------------
W
V
E
V
KG
Q
K
M
A
P
P
------------
Q
I
S
A
E
V
L
K
K
M
K
K
T
A
E
D
Y
L
G
E
P
V
T
E
A
V
I
T
V
P
A
Y
F
N
D
A
Q
R
Q
A
T
K
D
A
G
-
R
I
A
--------------
G
L
E
V
K
R
I
I
N
E
P
T
A
A
A
L
A
Y
G
L
-----
D
-
K
---
G
-------
T
--
G
N
R
T
I
A
V
Y
D
L
G
G
G
T
F
D
I
S
I
I
E
I
-
D
--
E
-------
V
DGE
K
T
F
E
V
L
A
-
T
-----
N
--
G
D
T
----
H
L
----
G
G
E
D
F
D
S
R
L
I
N
Y
L
V
E
E
F
K
K
---
D
-------------
Q
-------------
G
IDLRND
P
L
A
M
Q
R
L
K
E
A
A
E
K
A
K
I
E
L
S
S
A
-
Q
Q
-
T
D
-
V
N
L
-
P
Y
I
---------
T
A
D
A
------
T
----
G
-
P
K
H
M
N
I
K
V
T
R
A
K
L
---
E
S
L
V
E
D
L
------
V
-
N
R
S
I
E
P
L
K
V
A
L
Q
D
A
G
L
S
V
S
-
D
I
D
D
--
V
I
L
V
G
G
-------------
Q
--
T
R
-
M
-
P
M
--------------------
V
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
63.17
24%
-70
- C2 -
4JN4
7
DNAK_ECOLI
A:
[5-349]
-----------------------------------------------------
I
G
I
D
L
G
T
T
N
S
C
V
A
I
M
D
G
-
T
T
-
P
---------
R
---------
V
---------
L
E
N
AEGDRTT
P
S
I
I
A
Y
T
Q
--
D
------------
G
------
E
T
L
V
-----
G
Q
P
A
K
R
Q
A
V
T
N
P
Q
N
T
LFAIKRLIGRRFQD
E
E
V
Q
R
D
V
--------------------------------------
S
I
--------------------
M
P
F
-------------------------------
K
I
I
A
A
DNG
D
A
-------------
W
V
E
V
KG
Q
K
M
A
P
P
------------
Q
I
S
A
E
V
L
K
K
M
K
K
T
A
E
D
Y
L
G
E
P
V
T
E
A
V
I
T
V
P
A
Y
F
N
D
A
Q
R
Q
A
T
K
D
A
G
-
R
I
A
--------------
G
L
E
V
K
R
I
I
N
E
P
T
A
A
A
L
A
Y
G
L
-----
D
-
K
---
G
-------
T
--
G
N
R
T
I
A
V
Y
D
L
G
G
G
A
F
D
I
S
I
I
E
I
-
D
--
E
-------
V
DG
E
K
T
F
E
V
L
A
-
T
-----
N
--
G
D
T
----
H
L
----
G
G
E
D
F
D
S
R
L
I
N
Y
L
V
E
E
F
K
K
---
D
-------------
Q
-------------
G
IDLRND
P
L
A
M
Q
R
L
K
E
A
A
E
K
A
K
I
E
L
S
S
A
-
Q
Q
-
T
D
-
V
N
L
-
P
Y
I
---------
T
A
D
A
------
T
----
G
-
P
K
H
M
N
I
K
V
T
R
A
K
L
---
E
S
L
V
E
D
L
------
V
-
N
R
S
I
E
P
L
K
V
A
L
Q
D
A
G
L
S
V
S
-
D
I
D
D
--
V
I
L
V
G
G
-------------
Q
--
T
R
-
M
-
P
M
--------------------
V
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38
HHSearch
62.95
20%
-58
* C2 *
2FSJ
1
ACTH_THEAC
A:
[21-344]
--------------------------------------------------
M
V
V
V
G
L
D
V
G
Y
G
D
T
K
V
-
I
G
V
D
-
G
--
K
---------
R
---------
I
---------
I
F
--------
P
S
R
W
A
V
T
E
--
T
ESWK
I
P
V
L
S
TDG
G
------
Q
T
K
F
---
I
Y
G
K
Y
A
S
G
N
N
------------------------------------------------------------------
I
R
--------------------
V
P
Q
-------------------------------
G
-------
D
G
-------------
R
L
-------
A
S
K
------------
E
A
F
P
L
I
A
A
A
L
W
E
S
G
I
H
N
--
P
V
D
L
V
I
G
S
G
T
P
L
G
T
F
D
L
E
V
K
A
A
K
E
A
L
-
E
N
K
V
L
T
V
T
G
PEG
E
V
R
Q
F
N
I
T
R
L
I
M
R
P
Q
G
V
G
A
A
L
Y
L
L
N
-----
Q
-
G
I
I
E
Q
-------
Q
--
P
G
Y
G
V
V
I
-
D
V
G
S
R
T
T
D
V
L
T
I
N
L
-
M
DM
E
-------
P
VV-------
E
-
L
-----
S
--
F
S
L
----
Q
I
----
G
V
G
D
A
I
S
A
L
S
R
K
I
A
K
E
T
G
F
---
V
-------------
V
-------------
P
-------------
F
D
L
A
Q
E
A
L
S
H
----------------
P
V
---------
M
F
R
Q
--------------
K
--
Q
V
G
G
-
P
E
V
S
---
G
P
I
L
E
D
L
------
A
-
N
R
I
I
E
N
I
R
L
N
L
R
G
E
V
D
R
------
V
T
S
L
I
P
V
G
G
G
S
N
L
--
I
G
D
R
F
E
E
I
--
A
P
-
G
T
L
V
--------------------
K
I
K
P
E
D
L
Q
F
A
N
A
L
G
Y
R
D
A
A
E
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
56.02
31%
-64
- C2 -
2V7Y
2
DNAK_GEOKA
A:
[2-213]
--------------------------------------------------
S
K
I
I
G
I
D
L
G
T
T
N
S
C
V
-
A
V
L
E
-
G
G
-
E
---------
V
K
V
I
P
N
PEGN
R
---------
T
T
--------
P
S
V
V
A
F
K
N
--
G
------------
E
------
R
------
L
V
G
E
V
A
K
R
Q
A
I
T
N
P
N
T
I
--------------------
I
--------------------------------------
S
I
------------------------------------------------------
K
-------
R
H
-------------
M
G
-------
T
D
Y
K
V
E
I
EG
K
Q
Y
T
P
Q
E
I
S
A
I
I
L
Q
Y
L
K
S
Y
A
E
D
Y
L
G
E
P
V
T
R
A
V
I
T
V
P
A
Y
F
N
D
A
Q
R
Q
A
T
K
D
A
G
-
R
I
A
--------------
G
L
E
V
E
R
I
I
N
E
P
T
A
A
A
L
A
Y
G
L
-----
D
-
K
---
E
-------
E
--
D
Q
T
I
L
V
Y
-
D
L
G
G
G
T
F
D
V
S
I
L
E
L
-
G
D-
G
-------
V
---------
F
-
E
-----
V
--
K
A
T
A
G
D
N
H
L
----
G
G
D
D
F
D
Q
V
I
I
D
Y
L
V
N
Q
F
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------