@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Wbm0671: (2015-12-03 )
MYKALITCFIFLVCSFTRSYASDDVHLEKSETELYEEAVELFDQKKYKQAIRAFRKIEDLYPFSYWAMKAKLLSGISHYNMDDYSSAASDMDDYIYIYPNGEDLPYVYYLRVLSYYMQINRVQLGQQTAYKALELAAEYVNLFSESEYIEEMKEKVRLITDHILKKEYSIGKFYFRRGEYLAAIKRFQNIISSKDYSYFPRSINYLIAAYSALGLDLEAGQYESLLAENLKENTVEQ
Atome Classification :
(20 SA)
-------------------------------------------------------.......-..10........20...---.....30........40....--....50....------------------....60.-...-----....70........-80..-.-----------.....90........100.....-----..110...----------.-...120..-......130.......140----.......150..--------------------------------...-------------..160......-.170....------..----------.180.------......190.-.-.---.....---------200.......---210--------....-..----------...220.......230.....-----------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-------------------------------------------------------M
Y
K
A
L
I
T
-
C
F
I
F
L
V
C
S
F
T
R
SYASDD---
V
H
LE
K
S
E
T
E
L
Y
E
E
A
V
E
L
F
D
Q
K
--
K
Y
K
Q
A
I
R
A
F
R
------------------
K
I
E
D
LYP-
F
S
Y
-----
W
A
M
K
A
K
L
L
S
G
I
SHY-NMDD-Y-----------
S
S
A
ASDMD
D
Y
I
Y
I
YPNGEDL
P
Y
V
-----
Y
Y
L
R
V
L
S
Y
----------
Y
-
M
Q
I
N
R
-VQ-LG
Q
Q
T
A
Y
K
A
L
E
L
A
A
E
Y
V
N
L
----F
S
E
S
E
Y
I
E
E
M
K
E
--------------------------------
K
V
R
-------------
L
I
T
D
H
I
L
K
K
EY-SI
G
K
F
Y
FR------R
G
----------
E
Y
L
A
A
------
I
K
R
F
Q
N
I
I
-S-S-K---DYSYF---------
P
R
S
I
N
Y
L
I
A
A
---
Y
----------
S
ALG-LD----------LEA
G
Q
Y
E
S
L
L
A
E
N
L
K
E
NTVEQ-----------------------------
1
PsiBlast_PDB
93.31
21%
-87
- C3 -
2YHC
1
BAMD_ECOLI
A:
[3-219]
----------------------------------------------------------------------------------------
P
P
N
E
I
Y
A
T
A
Q
Q
K
L
Q
D
G
--
N
W
R
Q
A
I
T
Q
L
E
------------------
A
L
D
N
R
Y
P
-
F
G
P
-----
Y
S
Q
Q
V
Q
L
D
L
I
Y
A
Y
Y
-
K
N
A
D
-
L
-----------
P
L
A
Q
A
A
I
D
R
F
I
R
L
N
P
T
H
P
N
I
D
Y
V
-----
M
Y
M
R
G
L
T
N
M
A
L
D
D-----------------
D
P
Q
Q
A
R
A
A
F
S
D
F
S
K
L
V
R
G
----
Y
P
N
S
Q
Y
T
T
D
A
T
K
--------------------------------
R
L
V
-------------
F
L
K
D
R
L
A
K
Y
E
Y
-
S
V
A
E
Y
Y
T
E
------
R
G
----------
A
W
V
A
V
------
V
N
R
V
E
G
M
L
-
R
-
D
Y
P
---
D
T
Q
A
T
---------
R
D
A
L
P
L
M
E
N
A
---
Y
----------
R
Q
M
Q
-
M
N
----------
A
Q
A
E
K
V
A
K
I
I
A
A
N
-
S
S
N
T
L
E
H
-----------------------------
33
Fugue
91.92
23%
-82
- C3 -
3QKY
-
?
A:
[30-280]
-------------------------------------------------------------------------------------
R
H
S
S
P
Q
E
A
F
E
R
A
M
E
F
Y
N
Q
G
--
K
Y
D
R
A
I
E
Y
F
K
------------------
A
V
F
T
Y
G
R
-
T
H
E
-----
W
A
A
D
A
Q
F
Y
L
A
R
A
Y
Y
-
Q
N
K
E
-
Y
-----------
L
L
A
A
S
E
Y
E
R
F
I
Q
I
Y
Q
I
D
P
R
V
P
Q
A
-----
E
Y
E
R
A
M
C
Y
----------
Y
-
K
L
S
P
P
-
Y
E
-
L
D
Q
T
D
T
R
K
A
I
E
A
F
Q
L
F
I
D
R
----
Y
P
N
H
E
L
V
D
D
A
T
Q
--------------------------------
K
I
R
-------------
E
L
R
A
K
L
A
R
K
Q
Y
-
E
A
A
R
L
Y
E
R
------
R
E
----------
L
Y
E
A
A
------
A
V
T
Y
E
A
V
F
-
D
A
Y
-
P
---
D
T
P
W
A
---------
D
D
A
L
V
G
A
M
R
A
---
Y
----------
I
A
Y
A
-
E
Q
SVRARQ
P
E
R
Y
R
R
A
V
E
L
Y
E
R
L
L
Q
I
F
P
D
S
P
L
L
R
TA
E
E
L
Y
T
R
A
R
Q
R
L
T
E
L
E
G
DASLAQGQRQN
12
HHSearch
91.91
21%
-87
- C3 -
2YHC
1
BAMD_ECOLI
A:
[3-220]
----------------------------------------------------------------------------------------
P
P
N
E
I
Y
A
T
A
Q
Q
K
L
Q
D
G
--
N
W
R
Q
A
I
T
Q
L
E
------------------
A
L
D
N
R
Y
P
-
F
G
P
-----
Y
S
Q
Q
V
Q
L
D
L
I
Y
A
Y
Y
-
K
N
A
D
-
L
-----------
P
L
A
Q
A
A
I
D
R
F
I
R
L
N
P
T
H
P
N
I
D
Y
V
-----
M
Y
M
R
G
L
T
N
----------
M
-
A
L
D
D
------
D
P
Q
Q
A
R
A
A
F
S
D
F
S
K
L
V
R
G
----
Y
P
N
S
Q
Y
T
T
D
A
T
K
--------------------------------
R
L
V
-------------
F
L
K
D
R
L
A
K
Y
E
Y
-
S
V
A
E
Y
Y
T
E
------
R
G
----------
A
W
V
A
V
------
V
N
R
V
E
G
M
L
R
D
-
Y
-
P
---
D
T
Q
A
T
---------
R
D
A
L
P
L
M
E
N
A
---
Y
----------
R
Q
M
Q
-
M
N
----------
A
Q
A
E
K
V
A
K
I
I
A
A
N
S
S
N
T
L
E
H
H
-----------------------------
3
PsiBlast_PDB
89.02
20%
-87
- C3 -
3Q5M
6
BAMD_ECOLI
A:
[8-220]
--------------------------------------------------------------------------------------
D
N
P
P
N
E
I
Y
A
T
A
Q
Q
K
L
Q
D
G
--
N
W
R
Q
A
I
T
Q
L
E
------------------
A
L
D
N
R
Y
P
-
F
G
P
-----
Y
S
Q
Q
V
Q
L
D
L
I
Y
A
Y
Y
-
K
N
A
D
-
L
-----------
P
L
A
Q
A
A
I
D
R
F
I
R
L
N
P
T
H
P
N
I
D
Y
V
-----
M
Y
M
R
G
L
T
N
M
A
L
D
D
S---------------
R
D
P
Q
H
A
R
A
A
F
S
D
F
S
K
L
V
R
G
----
Y
P
N
S
Q
Y
T
T
D
A
T
K
--------------------------------
R
L
V
-------------
F
L
K
D
R
L
A
K
Y
E
Y
-
S
V
A
E
Y
Y
T
E
------
R
G
----------
A
W
V
A
V
------
V
N
R
V
E
G
M
L
-
R
-
D
Y
P
---
D
T
Q
A
T
---------
R
D
A
L
P
L
M
E
N
A
---
Y
----------
R
Q
M
Q
-
M
N
----------
A
Q
A
E
K
V
A
K
I
I
A
A
N
S
S
-----------------------------------
4
PsiBlast_PDB
88.06
20%
-89
- C3 -
3TGO
4
BAMD_ECOLI
A:
[13-225]
--------------------------------------------------------------------------------------
D
N
P
P
N
E
I
Y
A
T
A
Q
Q
K
L
Q
D
G
--
N
W
R
Q
A
I
T
Q
L
E
------------------
A
L
D
N
R
Y
P
-
F
G
P
-----
Y
S
Q
Q
V
Q
L
D
L
I
Y
A
Y
Y
-
K
N
A
D
-
L
-----------
P
L
A
Q
A
A
I
D
R
F
I
R
L
N
P
T
H
P
N
I
D
Y
V
-----
M
Y
M
R
G
L
T
N
M
A
L
D
D
S
A
L
Q
G
F
-
F
G
V
D
R
-
S
D
-
R
D
P
Q
H
A
R
A
A
F
S
D
F
S
K
L
V
R
G
----
Y
P
N
S
Q
Y
T
T
D
A
T
K
--------------------------------
R
L
V
-------------
F
L
K
D
R
L
A
K
Y
E
Y
-
S
V
A
E
Y
Y
T
E
------
R
G
----------
A
W
V
A
V
------
V
N
R
V
E
G
M
L
-
R
-
D
Y
P
---
D
T
Q
A
T
---------
R
D
A
L
P
L
M
E
N
A
---
Y
----------
R
Q
M
Q
-
M
N
----------
A
Q
A
E
K
V
A
K
I
I
A
A
N
S
------------------------------------
2
PsiBlast_PDB
87.68
26%
-93
- C3 -
3QKY
-
?
A:
[33-213]
----------------------------------------------------------------------------------------
S
P
Q
E
A
F
E
R
A
M
E
F
Y
N
Q
G
--
K
Y
D
R
A
I
E
Y
F
K
------------------
A
V
------
F
T
Y
GRTHE
W
A
A
D
A
Q
F
Y
L
A
R
A
Y
Y
-
Q
N
K
E
-
Y
-----------
L
L
A
A
S
E
Y
E
R
F
I
Q
I
Y
Q
I
D
P
R
V
P
Q
A
-----
E
Y
E
R
A
M
C
Y
----------
Y
-
K
L
S
P
P
-
Y
E
-
L
D
Q
T
D
T
R
K
A
I
E
A
F
Q
L
F
I
D
R
----
Y
P
N
H
E
L
V
D
D
A
T
Q
--------------------------------
K
I
R
-------------
E
L
R
A
K
L
A
R
K
Q
Y
-
E
A
A
R
L
Y
E
R
------
R
E
----------
L
Y
E
A
A
------
A
V
T
Y
E
A
V
F
-
D
-
A
------
Y
P
D
T
---------
P
W
A
D
D
A
L
V
G
A
---
M
----------
R
A
Y
I
-
A
Y
----------
A
E
Q
S
V
R
A
R
Q
P
E
R
Y
R
R
A
V
E
L
Y
E
-----------------------------
13
HHSearch
85.13
23%
-85
- C3 -
3QKY
-
?
A:
[30-249]
-------------------------------------------------------------------------------------
R
H
S
S
P
Q
E
A
F
E
R
A
M
E
F
Y
N
Q
G
--
K
Y
D
R
A
I
E
Y
F
K
------------------
A
V
F
T
Y
G
R
-
T
H
E
-----
W
A
A
D
A
Q
F
Y
L
A
R
A
Y
Y
-
Q
N
K
E
-
Y
-----------
L
L
A
A
S
E
Y
E
R
F
I
Q
I
Y
Q
I
D
P
R
V
P
Q
A
-----
E
Y
E
R
A
M
C
Y
----------
Y
-
K
L
S
P
P
-
Y
E
-
L
D
Q
T
D
T
R
K
A
I
E
A
F
Q
L
F
I
D
R
----
Y
P
N
H
E
L
V
D
D
A
T
Q
--------------------------------
K
I
R
-------------
E
L
R
A
K
L
A
R
K
Q
Y
-
E
A
A
R
L
Y
E
R
------
R
E
----------
L
Y
E
A
A
------
A
V
T
Y
E
A
V
F
D
A
-
Y
-
P
---
D
T
P
W
A
---------
D
D
A
L
V
G
A
M
R
A
---
Y
I
A
Y
A
E
Q
SVRA
R
Q
P
E
-
R
Y
----------
R
R
A
V
E
L
Y
E
R
L
L
Q
I
F
P
D
S
P
L
L
R
-----------------------------
20
HHSearch
71.16
19%
-60
- C3 -
3VTX
1
?
A:
[5-176]
-----------------------------------------------------------------------------------------
T
T
I
Y
M
D
I
G
D
K
K
R
T
K
G
--
D
F
D
G
A
I
R
A
Y
K
------------------
K
V
L
K
A
D
P
-
N
N
--------
V
E
T
L
L
K
L
G
K
T
Y
M
-
D
I
G
L
-
P
-----------
N
D
A
I
E
S
L
K
K
F
V
V
L
D
T
T
S
---
A
E
A
-----
Y
Y
I
L
G
S
A
N
----------
F
-
M
I
D
----------
E
K
Q
A
A
I
D
A
L
Q
R
A
I
A
L
----
N
T
V
Y
A
--------------------------------------------------------------
D
A
Y
Y
-
K
L
G
L
V
Y
D
S
------
M
G
----------
E
H
D
K
A
------
I
E
A
Y
E
K
T
I
S
I
-
K
-
P
---
G
F
------------
I
R
A
Y
Q
S
I
G
L
A
---
Y
----------
E
G
K
G
-
L
R
----------
D
E
A
V
K
Y
F
K
K
A
L
E
K
E
E
K
K
A
K
Y
E
-----------------------------
34
Fugue
64.96
20%
-82
* C3 *
2XEV
3
?
A:
[3-123]
------------------------------------------------------------------------------------------
R
T
A
Y
N
V
A
F
D
A
L
K
N
G
--
K
Y
D
D
A
S
Q
L
F
L
------------------
S
F
L
E
L
Y
P
-
N
G
V
-----
Y
T
P
N
A
L
Y
W
L
G
E
S
Y
Y
-
A
T
R
N
-
F
-----------
Q
L
A
E
A
Q
F
R
D
L
V
S
R
Y
P
T
H
D
K
A
A
G
G
-----
L
L
K
L
G
L
S
Q
----------
Y
-
G
E
G
K
-------
N
T
E
A
Q
Q
T
L
Q
Q
V
A
T
Q
Y
P
G
----
S
D
A
A
R
V
A
Q
E
R
L
Q
--------------------------------
S
I
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
HHSearch
64.09
14%
-64
- C3 -
3AS5
1
?
A:
[7-178]
----------------------------------------------------------------------------------------
R
Q
V
Y
Y
R
D
K
G
I
S
H
A
K
A
G
--
R
Y
S
Q
A
V
M
L
L
E
------------------
Q
V
Y
D
A
D
A
-
F
D
--------
V
D
V
A
L
H
L
G
I
A
Y
V
-
K
T
G
A
-
V
-----------
D
R
G
T
E
L
L
E
R
S
L
A
D
A
P
D
N
---
V
K
V
-----
A
T
V
L
G
L
T
Y
----------
V
-
Q
V
Q
----------
K
Y
D
L
A
V
P
L
L
I
K
V
A
E
A
----
N
P
I
N
F
--------------------------------------------------------------
N
V
R
F
-
R
L
G
V
A
L
D
N
------
L
G
----------
R
F
D
E
A
------
I
D
S
F
K
I
A
L
G
L
-
R
-
P
---
N
E
------------
G
K
V
H
R
A
I
A
F
S
---
Y
----------
E
Q
M
G
-
R
H
----------
E
E
A
L
P
H
F
K
K
A
N
E
L
D
E
G
A
S
V
E
L
-----------------------------
23
HHSearch
61.40
11%
-66
- C3 -
2VQ2
6
?
A:
[5-179]
--------------------------------------------------------------------------------------
N
Q
V
S
N
I
K
T
Q
L
A
M
E
Y
M
R
G
Q
--
D
Y
R
Q
A
T
A
S
I
E
------------------
D
A
L
K
S
D
P
-
K
N
--------
E
L
A
W
L
V
R
A
E
I
Y
Q
-
Y
L
K
V
-
N
-----------
D
K
A
Q
E
S
F
R
Q
A
L
S
I
K
P
D
S
---
A
E
I
-----
N
N
N
Y
G
W
F
L
----------
C
G
R
L
N
----------
R
P
A
E
S
M
A
Y
F
D
K
A
L
A
-----
D
P
T
Y
P
T
-----------------------------------------------------------
P
Y
I
A
N
L
-
N
K
G
I
C
S
A
K
------
Q
G
----------
Q
F
G
L
A
------
E
A
Y
L
K
R
S
L
A
A
-
Q
-
P
---
Q
F
------------
P
P
A
F
K
E
L
A
R
T
---
K
----------
M
L
A
G
-
Q
L
----------
G
D
A
D
Y
Y
F
K
K
Y
Q
S
R
V
E
V
L
Q
A
D
D
-----------------------------
14
HHSearch
61.39
14%
-77
- C3 -
2VQ2
5
?
A:
[40-217]
---------------------------------------------------------------------------------------
K
N
E
L
A
W
L
V
R
A
E
I
Y
Q
Y
L
K
--
V
N
D
K
A
Q
E
S
F
R
------------------
Q
A
L
S
I
K
P
-
D
S
--------
A
E
I
N
N
N
Y
G
W
F
L
C
G
R
L
N
R
-
P
-----------
A
E
S
M
A
Y
F
D
K
A
L
A
-
D
P
T
Y
P
T
P
Y
I
A
-----
N
L
N
K
G
I
C
S
----------
A
-
K
Q
G
----------
Q
F
G
L
A
E
A
Y
L
K
R
S
L
A
A
----
Q
P
Q
F
--------------------------------------------------------------
P
P
A
F
K
-
E
L
A
R
T
K
M
L
------
A
G
----------
Q
L
G
D
A
------
D
Y
Y
F
K
K
Y
Q
S
R
-
V
-
E
---
V
L
--
Q
---------
A
D
D
L
L
L
G
W
K
I
---
A
----------
K
A
L
G
-
N
A
----------
Q
A
A
Y
E
Y
E
A
Q
L
Q
A
N
F
P
Y
S
E
E
L
Q
-----------------------------
25
HHSearch
61.11
13%
-59
- C3 -
2Y4T
-
DNJC3_HUMAN
A:
[34-256]
--------------------------------------------------------------------------------------
M
A
D
V
E
K
H
L
E
L
G
K
K
L
L
A
A
G
--
Q
L
A
D
A
L
S
Q
F
H
------------------
A
A
V
D
G
D
P
-
D
N
--------
Y
I
A
Y
Y
R
R
A
T
V
F
L
-
A
M
G
K
-
S
-----------
K
A
A
L
P
D
L
T
K
V
I
Q
L
K
M
D
F
---
T
A
A
-----
R
L
Q
R
G
H
L
L
----------
L
-
K
Q
G
----------
K
L
D
E
A
E
D
D
F
K
K
V
L
K
S
----
N
P
S
E
N
E
E
K
E
A
Q
S
Q
L
I
K
S
D
E
M
Q
R
L
R
S
Q
A
L
N
A
F
G
S
GD
Y
T
A
A
I
A
F
L
D
K
I
L
-------------
E
V
C
V
W
D
A
E
L
R
E
-
L
R
A
E
C
F
I
K
------
E
G
----------
E
P
R
K
A
------
I
S
D
L
K
A
A
S
K
L
-
K
-
N
---
D
N
------------
T
E
A
F
Y
K
I
S
T
L
---
Y
----------
Y
Q
L
G
-
D
H
----------
E
L
S
L
S
E
V
R
E
C
L
K
L
D
Q
D
H
K
R
C
F
-----------------------------
35
Fugue
59.93
17%
-46
- C3 -
1E96
-
NCF2_HUMAN
B:
[2-186]
-------------------------------------------------------------------------------------
S
L
V
E
A
I
S
L
W
N
E
G
V
L
A
A
D
K
K
--
D
W
K
G
A
L
D
A
F
S
------------------
A
V
Q
D
P
H
------------
S
R
I
C
F
N
I
G
C
M
Y
T
-
I
L
K
N
-
M
-----------
T
E
A
E
K
A
F
T
R
S
I
N
R
D
K
H
L
---
A
V
A
-----
Y
F
Q
R
G
M
L
Y
----------
Y
-
Q
T
E
K
-------
Y
D
L
A
I
K
D
L
K
E
A
L
I
Q
L
R
G
----
N
Q
L
I
D
Y
----
K
I
--------------------------------
L
G
L
-------------
Q
F
K
L
F
A
C
E
V
L
Y
-
N
I
A
F
M
Y
A
K
------
K
E
----------
E
W
K
K
A
------
E
E
Q
L
A
L
A
T
-
S
-
M
-
K
---
S
-------------
E
P
R
H
S
K
I
D
K
A
---
M
----------
E
C
V
W
-
K
Q
----------
K
L
Y
E
P
V
V
I
P
V
G
K
L
F
R
P
N
---------------------------------
41
Fugue
56.07
16%
-62
- C1 -
4NDN
1
MAT2B_HUMAN
F:
[15-323]
-----------------------------------------------------IP
N
R
R
V
L
V
T
G
A
T
G
L
L
G
R
A
V
H
K
E
F
Q
Q
N
N
WHA
V
G
C
G
F
R
R
A
R
P
K
F
E
Q
V
N
L
L
D
S
N
--
A
V
H
H
I
I
H
D
F
Q
PHVIVHCAAERRPDVDAA
S
Q
L
N
V
D
A
-
S
G
N
-----
L
A
K
E
A
A
A
V
G
A
F
L
I
Y
-
I
S
S
D
-
Y
VFDGTNPPYRE
E
D
I
P
A
P
L
N
L
Y
G
K
T
K
L
D
G
E
K
A
V
L
E
NNLGA
A
V
L
R
I
P
I
L
----------
Y
-
G
E
V
E
K
-
L
E
E
S
A
V
T
V
M
F
D
K
V
Q
F
S
N
K
S
A
N
M
DHWQ
Q
R
F
P
T
H
V
K
D
V
A
T
--------------------------------
V
C
R
-------------
Q
L
A
E
K
R
M
L
D
P
S
-
I
K
G
T
F
H
W
S
GNEQMT
K
Y
----------
E
M
A
C
A
------
I
A
D
A
F
N
L
P
-
S
-
S
-
H
---
L
R
P
I
T
DSPVLGAQR
P
R
N
A
Q
L
D
C
S
K
---
L
----------
E
T
L
G
-
I
G
QRTP------
F
R
I
G
I
K
E
S
L
W
P
F
L
I
D
K
R
W
R
Q
T
VFH--------------------------
24
HHSearch
55.33
12%
-64
- C3 -
2Q7F
-
YRRB_BACSU
A:
[57-229]
----------------------------------------------------------------------------------------
D
A
I
P
Y
I
N
F
A
N
L
L
S
S
V
N
--
E
L
E
R
A
L
A
F
Y
D
------------------
K
A
L
E
L
D
S
-
S
A
--------
A
T
A
Y
Y
G
A
G
N
V
Y
V
-
V
K
E
M
-
Y
-----------
K
E
A
K
D
M
F
E
K
A
L
R
A
G
M
E
N
---
G
D
L
-----
F
Y
M
L
G
T
V
L
----------
V
-
K
L
E
----------
Q
P
K
L
A
L
P
Y
L
Q
R
A
V
E
L
----
N
E
N
D
T
--------------------------------------------------------------
E
A
R
F
-
Q
F
G
M
C
L
A
N
------
E
G
----------
M
L
D
E
A
------
L
S
Q
F
A
A
V
T
E
Q
-
D
-
P
---
G
H
------------
A
D
A
F
Y
N
A
G
V
T
---
Y
----------
A
Y
K
E
-
N
R
----------
E
K
A
L
E
M
L
D
K
A
I
D
I
Q
P
D
H
M
L
A
L
-----------------------------
39
Fugue
54.25
13%
-51
- C3 -
1FCH
2
PEX5_HUMAN
A:
[46-368]
SATYDKGYQFEEENPLRDHPQ
P
F
E
E
G
L
R
R
L
Q
E
GD
L
P
N
A
V
L
L
F
E
A
A
V
Q
Q
D
PKH
M
E
A
W
Q
Y
L
G
T
T
-
Q
A
E
N
E
Q
E
L
L
A
I
S
A
L
R
R
C
---
L
E
L
K
P
D
N
Q
T
A
L
M
A
L
A
V
S
F
T
N
E
S-
L
Q
R
Q
A
C
E
I
L
R
------------------
D
W
L
R
Y
T
P
-
A
Y
A
-----
H
L
V
T
R
I
---
L
G
S
L
L
-
S
D
S
L
-
F
-----------
L
E
V
K
E
L
F
L
A
A
V
R
L
D
P
T
S
I
D
P
D
V
Q
-----
C
G
L
G
V
L
F
N
L
S
GE
Y
D
K
A
--
V
-
D
C
F
T
A
-
A
L
-
S
V
R
P
N
D
Y
L
L
W
N
K
L
G
A
T
L
A
N
----
G
N
Q
S
E
E
A
V
A
A
Y
R
--------------------------------
R
A
L
-------------
E
L
Q
P
G
Y
I
R
S
R
Y
-
N
L
G
I
S
C
I
N
------
L
G
----------
A
H
R
E
A
------
V
E
H
F
L
E
A
L
-
N
-
M
-
Q
R
K
S
G
G
A
M
S
---------
E
N
I
W
S
T
L
R
L
A
---
L
----------
S
M
L
G
Q
S
D
----------
A
Y
G
A
A
D
A
R
D
L
S
T
L
L
T
M
F
G
L
P
Q
-----------------------------
26
HHSearch
52.51
14%
-47
- C3 -
1XNF
1
NLPI_ECOLI
A:
[40-247]
--------------------------------------------------------------------------------------
D
E
R
A
Q
L
L
Y
E
R
G
V
L
Y
D
S
L
G
--
L
R
A
L
A
R
N
D
F
S
------------------
Q
A
L
A
I
R
P
-
D
M
--------
P
E
V
F
N
Y
L
G
I
Y
L
T
-
Q
A
G
N
-
F
-----------
D
A
A
Y
E
A
F
D
S
V
L
E
L
D
P
T
Y
---
N
Y
A
-----
H
L
N
R
G
I
A
L
----------
Y
-
Y
G
G
----------
R
D
K
L
A
Q
D
D
L
L
A
F
Y
Q
D
----
D
P
N
D
P
F
R
S
L
W
L
Y
--------------------------------
L
A
E
Q
K
L
D
E
K
Q
A
K
E
V
L
K
Q
H
F
E
K
S
D
K
E
Q
W
-
G
W
N
I
V
E
F
Y
------
L
G
----------
N
I
S
E
Q
T
L
M
E
R
L
K
A
D
A
T
D
N
T
S
L
-
A
-
E
------
H
L
---------
S
E
T
N
F
Y
L
G
K
Y
---
Y
----------
L
S
L
G
-
D
L
----------
D
S
A
T
A
L
F
K
L
A
V
A
N
N
V
H
N
F
V
E
H
-----------------------------
18
HHSearch
52.39
12%
-65
- C3 -
1XNF
1
NLPI_ECOLI
A:
[7-177]
-------------------------------------------------------------------------------------------
K
S
E
V
L
A
V
P
L
Q
P
T
L
--
Q
Q
E
V
I
L
A
R
M
E
------------------
Q
I
L
A
S
R
A
L
T
D
D
-----
E
R
A
Q
L
L
Y
E
R
G
V
L
Y
D
-
S
L
G
L
-
R
-----------
A
L
A
R
N
D
F
S
Q
A
L
A
I
R
P
D
M
---
P
E
V
-----
F
N
Y
L
G
I
Y
L
----------
T
-
Q
A
G
----------
N
F
D
A
A
Y
E
A
F
D
S
V
L
E
L
----
D
P
T
Y
N
--------------------------------------------------------------
Y
A
H
L
-
N
R
G
I
A
L
Y
Y
------
G
G
----------
R
D
K
L
A
------
Q
D
D
L
L
A
F
Y
Q
D
-
D
-
P
---
N
D
P
------------
F
R
S
L
W
L
Y
L
A
---
E
-----------
Q
K
L
-
D
E
----------
K
Q
A
K
E
V
L
K
Q
H
F
E
K
S
D
K
E
Q
W
G
W
-----------------------------
32
HHSearch
51.66
10%
-47
- C3 -
3DSS
-
?
A:
[103-310]
------------------------------------------------------------------------------------
V
N
P
K
S
Y
G
T
W
H
H
R
C
W
L
L
S
R
L
P
EP
N
W
A
R
E
L
E
L
C
A
------------------
R
F
L
E
A
D
E
-
R
N
--------
F
H
C
W
D
Y
R
R
F
V
A
A
-
Q
A
A
V
A
P
-----------
A
E
E
L
A
F
T
D
S
L
I
T
R
N
F
S
N
---
Y
S
S
-----
W
H
Y
R
S
C
L
L
----------
P
-
Q
L
H
P
Q
P-
R
-
L
P
E
N
V
L
L
K
E
L
E
L
V
Q
N
A
F
F
T
----
D
P
N
D
Q
S
--------------------------------------------------------------
A
W
F
Y
H
R
W
L
L
G
A
G
------
S
G
RCELS
V
E
K
S
T
V
L
Q
S
E
------
L
E
S
C
K
E
L
Q
E
L
-
E
-
P
---
E
N
K
------------
W
C
L
L
T
I
I
L
L
M
R
A
L
----------
D
P
L
L
-
Y
E
----------
K
E
T
L
Q
Y
F
S
T
L
K
A
V
D
P
M
R
A
A
Y
L
-----------------------------