@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo0038: (2016-03-11 )
MRTIDSSSKKDGFRMPGEFEKHAGCYIIWPERPDNWRLGAKPAQKAFVDVATAISHFEPVTVVASSSQYVNARYMLSDEIRVVEMDNDDAWVRDSGPTFVVNDSGDVRGVDWSFNSWGGLVDGLYFPWDKDDQVAQKICELERKDRYRLADFVLEGGSIHVDGEGTLVTTEECLLSEGRNPQLSKQQIEMVLKEYLNLEKIIWLKRGIYLDETNGHVDNIFNYVRPGVVALAWTDDETDPQYEISKECFDILSNETDAKGRKLEVHKINVPKPILITDEESKGVDAVEGTLPREEGDRLAASYINYYTANGGVIFPLFGDPNDELAREKLQQLYPNCEVVGVKAREILLGGGNIHCITQQVPR
Atome Classification :
(20 SA)
.........10....-....20........30..----.-----.----------..--..40........50.....-...60.-..-....-------.-70---..-.-------------------------------------.---------..---------..------.-------------------------80..------------...-.-..90........100.-.---..-...---110.......120.......130.......140-----.-.-----....------.--.150-.......160.......170.......180.-......190....------.----.--.200.......-..210.-.-.......-220.......230.......-240-------.--...-----.------------....250.......260........270-.......280.......290.......300.......310........-320.-.......330.......340-.-.....--.350.......360.-----------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MRTIDSSSKKDGFRM-PGE
F
E
KHA
G
C
Y
I
I
WPERP----D-----N----------WR--LGAK
P
A
Q
K
A
F
V
D
V
A
T
A
I
SH-FE
P
V
T
V
-
V
A-SSS
Q
-------
Y
-
V
----
N
A
-
R
-------------------------------------
Y
---------
M
L---------SD------
E
-------------------------
I
R
V
V
------------
E
MD-N-DD
A
W
VRDSG
P
T
F
V
VND-S---GD-
V
R
G
---
V
DWSFNSWGGLVDGLYFPWDK
D
D
Q
V
A
Q
K
I
C
E
L
------
E
-
R
-----KDR
Y
------
R
--
L
A
D
F
-
V
LEG
G
S
I
H
VDGEG
T
L
V
T
T
E
E
C
L
LSEGRNPQL-
S
K
Q
Q
I
E
M
V
L
K
E
Y
L------
N
----
L
--
E
K
--
I
I
W
L
KRG-
I
Y
L
--D-E-TNG
H
V
D
N
-
I
F
N
Y
VRP
G
V
V
A
L
A
WTDDETD-P---------
Q
--
Y
E
I
-----
S
------------
K
E
C
F
D
I
LSNETDAKG-
R
K
L
E
V
H
KINVPK-
P
I
L
I
TDEESKGVDAVEGTLP
R
E
E
G
D
R
L
A
A
S
Y
I
N
Y
Y
TAN-G
G
V
I
F
P
LFG-DP-
N
-
D
E
L
A
R
E
K
L
Q
Q
LYPN
C
E
V
V
G
V
-
K
-
A
R
E
I
L
--LGGG
N
I
H
C
I
TQQVPR-----------------------------------------------------------------------------------------------------------
67
HHSearch
98.30
55%
-86
- C3 -
3H7C
7
AGUA_ARATH
X:
[4-373]
---
S
R
E
S
P
A
E
H
G
Y
Y
M
-
P
A
E
W
D
S
H
A
Q
T
W
I
G
W
P
E
R
Q
----
D
-----
N
----------
W
R
--
H
N
A
L
P
A
Q
R
V
F
A
G
V
A
K
A
I
S
K
-
F
E
P
V
T
V
-
C
A
-
S
P
A
Q
-------
W
-
E
----
N
A
-
R
-------------------------------------
K
---------
Q
L
---------
P
E
------
D
-------------------------
I
R
V
V
------------
E
M
S
-
M
-
N
D
S
W
F
R
D
S
G
P
T
F
I
V
R
K
-
R
N--
R
N
-
I
A
G
---
I
D
W
N
F
N
A
W
G
G
A
N
D
G
C
Y
N
D
W
S
H
D
L
L
V
S
R
K
I
L
A
L
------
E
-
R
-----
I
P
R
F
------
Q
---
H
S
M
-
I
L
E
G
G
S
I
H
V
D
G
E
G
T
C
L
V
T
E
E
C
L
L
N
K
N
R
N
P
H
M
-
S
K
E
Q
I
E
E
E
L
K
K
Y
L
------
G
----
V
--
Q
S
--
F
I
W
L
P
R
G
-
L
Y
G
--
D
E
D
-
T
N
G
H
I
D
N
-
M
C
C
F
A
R
P
G
V
V
L
L
S
W
T
D
D
E
T
D
-
P
---------
Q
--
Y
E
R
-----
S
------------
V
E
A
L
S
V
L
S
N
S
I
D
A
R
G
-
R
K
I
Q
V
I
K
L
Y
I
P
E
-
P
L
Y
M
T
E
E
E
S
S
G
I
T
Q
D
G
E
A
I
P
R
L
A
G
T
R
L
A
A
S
Y
V
N
F
Y
I
A
N
-
G
G
I
I
A
P
Q
F
G
-
D
P
I
R
-
D
K
E
A
I
R
V
L
S
D
T
F
P
H
H
S
V
V
G
I
E
N
-
A
R
E
I
V
--
L
A
G
G
N
I
H
C
I
T
Q
Q
Q
P
A
-----------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
96.64
53%
-86
- C3 -
3H7C
7
AGUA_ARATH
X:
[7-372]
------
S
P
A
E
H
G
Y
Y
M
-
P
A
E
W
D
S
H
A
Q
T
W
I
G
W
P
E
R
Q
----
D
-----
N
----------
W
R
--
H
N
A
L
P
A
Q
R
V
F
A
G
V
A
K
A
I
S
K
-
F
E
P
V
T
V
-
C
A
-
S
P
A
Q
-------
W
-
E
----
N
A
-
R
-------------------------------------
K
---------
Q
L
---------
P
E
------
D
-------------------------
I
R
V
V
------------
E
M
S
-
M
-
N
D
S
W
F
R
D
S
G
P
T
F
I
V
R
K
R
N
---
R
N
-
I
A
G
---
I
D
W
N
F
N
A
W
G
G
A
N
D
G
C
Y
N
D
W
S
H
D
L
L
V
S
R
K
I
L
A
L
------
E
-
R
-----
I
P
R
F
------
Q
--
H
S
M
--
I
L
E
G
G
S
I
H
V
D
G
E
G
T
C
L
V
T
E
E
C
L
L
N
K
N
R
N
P
H
M
-
S
K
E
Q
I
E
E
E
L
K
K
Y
L
------
G
----
V
--
Q
S
--
F
I
W
L
P
R
G
-
L
Y
G
--
D
-
E
D
T
N
G
H
I
D
N
-
M
C
C
F
A
R
P
G
V
V
L
L
S
W
T
D
D
E
T
D
-
P
---------
Q
--
Y
E
R
-----
S
------------
V
E
A
L
S
V
L
S
N
S
I
D
A
R
G
-
R
K
I
Q
V
I
K
L
Y
I
P
E
-
P
L
Y
M
T
E
E
E
S
S
G
I
T
Q
D
G
E
A
I
P
R
L
A
G
T
R
L
A
A
S
Y
V
N
F
Y
I
A
N
-
G
G
I
I
A
P
Q
F
G
-
D
P
I
R
-
D
K
E
A
I
R
V
L
S
D
T
F
P
H
H
S
V
V
G
I
-
E
N
A
R
E
I
V
--
L
A
G
G
N
I
H
C
I
T
Q
Q
Q
P
------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
96.06
53%
-82
- C3 -
1VKP
9
AGUA_ARATH
A:
[7-372]
------
S
P
A
E
H
G
Y
Y
M
-
P
A
E
W
D
S
H
A
Q
T
W
I
G
W
P
E
R
Q
----
D
-----
N
----------
W
R
--
H
N
A
L
P
A
Q
R
V
F
A
G
V
A
K
A
I
S
K
-
F
E
P
V
T
V
-
C
A
-
S
P
A
Q
-------
W
-
E
----
N
A
-
R
-------------------------------------
K
---------
Q
L
---------
P
E
------
D
-------------------------
I
R
V
V
------------
E
M
S
-
M
-
N
D
S
W
F
R
D
S
G
P
T
F
I
V
R
K
R
N
---
R
N
-
I
A
G
---
I
D
W
N
F
N
A
W
G
G
A
N
D
G
C
Y
N
D
W
S
H
D
L
L
V
S
R
K
I
L
A
L
------
E
-
R
-----
I
P
R
F
------
Q
--
H
S
M
--
I
L
E
G
G
S
I
H
V
D
G
E
G
T
C
L
V
T
E
E
C
L
L
N
K
N
R
N
P
H
M
-
S
K
E
Q
I
E
E
E
L
K
K
Y
L
------
G
----
V
--
Q
S
--
F
I
W
L
P
R
G
-
L
Y
G
--
D
-
E
D
T
N
G
H
I
D
N
-
M
C
C
F
A
R
P
G
V
V
L
L
S
W
T
D
D
E
T
D
-
P
---------
Q
--
Y
E
R
-----
S
------------
V
E
A
L
S
V
L
S
N
S
I
D
A
R
G
-
R
K
I
Q
V
I
K
L
Y
I
P
E
-
P
L
Y
M
T
E
E
E
S
S
G
I
T
Q
D
G
E
A
I
P
R
L
A
G
T
R
L
A
A
S
Y
V
N
F
Y
I
A
N
-
G
G
I
I
A
P
Q
F
G
-
D
P
I
R
-
D
K
E
A
I
R
V
L
S
D
T
F
P
H
H
S
V
V
G
I
-
E
N
A
R
E
I
V
--
L
A
G
G
N
I
H
C
I
T
Q
Q
Q
P
------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
96.05
58%
-78
* C3 *
2JER
1
AGUA_ENTFA
H:
[4-356]
-
R
I
V
G
S
T
P
K
Q
D
G
F
R
M
-
P
G
E
F
E
P
Q
E
K
V
W
M
I
W
P
E
R
P
----
D
-----
N
----------
W
R
--
D
G
G
K
P
V
Q
E
A
F
T
N
V
A
K
A
I
S
Q
-
F
T
P
M
N
V
-
V
V
-
S
Q
Q
Q
-------
F
-
Q
----
N
C
-
R
-------------------------------------
R
---------
Q
L
---------
P
P
------
E
-------------------------
I
T
V
Y
------------
E
M
S
-
N
-
N
D
A
W
V
R
D
C
G
P
S
F
V
I
N
D
-
H
---
G
E
-
I
R
G
---
V
D
W
T
F
N
A
W
G
G
L
V
D
G
L
Y
F
P
W
D
Q
D
D
L
V
A
Q
K
I
C
E
I
------
E
-
H
-----
V
D
S
Y
------
R
--
T
D
D
F
-
V
L
E
G
G
S
F
H
V
D
G
Q
G
T
V
L
T
T
E
M
C
L
L
S
E
G
R
N
P
Q
L
-
S
K
E
A
I
E
Q
K
L
C
D
Y
L
------
N
----
V
--
E
K
--
V
L
W
L
G
D
G
-
I
D
P
--
E
-
E
-
T
N
G
H
V
D
D
-
V
A
C
F
I
A
P
G
E
V
A
C
I
Y
T
E
D
Q
N
S
-
P
---------
F
--
Y
E
A
-----
A
------------
Q
D
A
Y
Q
R
L
L
K
M
T
D
A
K
G
-
R
Q
L
K
V
H
K
L
C
C
P
V
-
K
-
N
V
T
I
K
G
S
F
K
I
D
F
V
E
G
T
M
P
R
E
D
G
D
I
C
I
A
S
Y
M
N
F
L
I
T
N
-
D
G
V
I
V
P
Q
Y
G
-
D
E
-
N
-
D
R
L
A
L
E
Q
V
Q
T
M
F
P
D
K
K
I
V
G
V
-
N
-
T
V
E
V
V
--
Y
G
G
G
N
I
H
-------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
95.80
58%
-81
- C3 -
2JER
1
AGUA_ENTFA
G:
[4-356]
-
R
I
V
G
S
T
P
K
Q
D
G
F
R
M
-
P
G
E
F
E
P
Q
E
K
V
W
M
I
W
P
E
R
P
----
D
-----
N
----------
W
R
--
D
G
G
K
P
V
Q
E
A
F
T
N
V
A
K
A
I
S
Q
-
F
T
P
M
N
V
-
V
V
-
S
Q
Q
Q
-------
F
-
Q
----
N
C
-
R
-------------------------------------
R
---------
Q
L
---------
P
P
------
E
-------------------------
I
T
V
Y
------------
E
M
S
-
N
-
N
D
A
W
V
R
D
C
G
P
S
F
V
I
N
D
-
H
---
G
E
-
I
R
G
---
V
D
W
T
F
N
A
W
G
G
L
V
D
G
L
Y
F
P
W
D
Q
D
D
L
V
A
Q
K
I
C
E
I
------
E
-
H
-----
V
D
S
Y
------
R
--
T
D
D
F
-
V
L
E
G
G
S
F
H
V
D
G
Q
G
T
V
L
T
T
E
M
C
L
L
S
E
G
R
N
P
Q
L
-
S
K
E
A
I
E
Q
K
L
C
D
Y
L
------
N
----
V
--
E
K
--
V
L
W
L
G
D
G
-
I
D
P
--
E
-
E
-
T
N
G
H
V
D
D
-
V
A
C
F
I
A
P
G
E
V
A
C
I
Y
T
E
D
Q
N
S
-
P
---------
F
--
Y
E
A
-----
A
------------
Q
D
A
Y
Q
R
L
L
K
M
T
D
A
K
G
-
R
Q
L
K
V
H
K
L
C
C
P
V
-
K
-
N
V
T
I
K
G
S
F
K
I
D
F
V
E
G
T
M
P
R
E
D
G
D
I
C
I
A
S
Y
M
N
F
L
I
T
N
-
D
G
V
I
V
P
Q
Y
G
-
D
E
-
N
-
D
R
L
A
L
E
Q
V
Q
T
M
F
P
D
K
K
I
V
G
V
-
N
-
T
V
E
V
V
--
Y
G
G
G
N
I
H
-------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
95.68
53%
-79
- C3 -
2Q3U
9
AGUA_ARATH
A:
[7-372]
------
S
P
A
E
H
G
Y
Y
M
-
P
A
E
W
D
S
H
A
Q
T
W
I
G
W
P
E
R
Q
----
D
-----
N
----------
W
R
--
H
N
A
L
P
A
Q
R
V
F
A
G
V
A
K
A
I
S
K
-
F
E
P
V
T
V
-
C
A
-
S
P
A
Q
-------
W
-
E
----
N
A
-
R
-------------------------------------
K
---------
Q
L
---------
P
E
------
D
-------------------------
I
R
V
V
------------
E
M
S
-
M
-
N
D
S
W
F
R
D
S
G
P
T
F
I
V
R
K
R
N
---
R
N
-
I
A
G
---
I
D
W
N
F
N
A
W
G
G
A
N
D
G
C
Y
N
D
W
S
H
D
L
L
V
S
R
K
I
L
A
L
------
E
-
R
-----
I
P
R
F
------
Q
--
H
S
M
--
I
L
E
G
G
S
I
H
V
D
G
E
G
T
C
L
V
T
E
E
C
L
L
N
K
N
R
N
P
H
M
-
S
K
E
Q
I
E
E
E
L
K
K
Y
L
------
G
----
V
--
Q
S
--
F
I
W
L
P
R
G
-
L
Y
G
--
D
-
E
D
T
N
G
H
I
D
N
-
M
C
C
F
A
R
P
G
V
V
L
L
S
W
T
D
D
E
T
D
-
P
---------
Q
--
Y
E
R
-----
S
------------
V
E
A
L
S
V
L
S
N
S
I
D
A
R
G
-
R
K
I
Q
V
I
K
L
Y
I
P
E
-
P
L
Y
M
T
E
E
E
S
S
G
I
T
Q
D
G
E
A
I
P
R
L
A
G
T
R
L
A
A
S
Y
V
N
F
Y
I
A
N
-
G
G
I
I
A
P
Q
F
G
-
D
P
I
R
-
D
K
E
A
I
R
V
L
S
D
T
F
P
H
H
S
V
V
G
I
-
E
N
A
R
E
I
V
--
L
A
G
G
N
I
H
C
I
T
Q
Q
Q
P
------------------------------------------------------------------------------------------------------------
81
Fugue
94.80
56%
-74
- C3 -
1VKP
9
AGUA_ARATH
A:
[5-376]
-----
R
E
S
P
A
E
H
G
Y
Y
M
P
A
E
W
D
S
H
A
Q
T
W
I
G
W
P
E
R
Q
----
D
-----
N
----------
W
R
--
H
N
A
L
P
A
Q
R
V
F
A
G
V
A
K
A
I
S
K
-
F
E
P
V
T
V
-
C
A
-
S
P
A
Q
-------
W
-
E
----
N
A
-
R
-------------------------------------
K
---------
Q
L
---------
P
E
------
D
-------------------------
I
R
V
V
------------
E
--
M
S
M
N
D
S
W
F
R
D
S
G
P
T
F
I
V
R
K
-
R
---
N
R
N
I
A
G
---
I
D
W
N
F
N
A
W
G
G
A
N
D
G
C
Y
N
D
W
S
H
D
L
L
V
S
R
K
I
L
A
L
------
E
-
R
-----
I
P
R
F
------
Q
----
H
S
M
I
L
E
G
G
S
I
H
V
D
G
E
G
T
C
L
V
T
E
E
C
L
L
N
K
N
R
N
P
H
-M
S
K
E
Q
I
E
E
E
L
K
K
Y
L
------
G
----
V
--
Q
S
--
F
I
W
L
P
R
G
-
L
Y
G
--
D
-
E
D
T
N
G
H
I
D
N
M
C
-
C
F
A
R
P
G
V
V
L
L
S
W
T
D
D
E
T
D
-
P
---------
Q
--
Y
E
R
-----
S
------------
V
E
A
L
S
V
L
S
N
S
I
D
A
R
G
-
R
K
I
Q
V
I
K
L
Y
I
P
E
-
P
L
Y
M
T
E
E
E
S
S
G
I
T
Q
D
G
E
A
I
P
R
L
A
G
T
R
L
A
A
S
Y
V
N
F
Y
I
A
N
-
G
G
I
I
A
P
Q
F
G
-
D
P
I
R
-
D
K
E
A
I
R
V
L
S
D
T
F
P
H
H
S
V
V
G
I
-
E
N
A
R
E
I
V
--
L
A
G
G
N
I
H
C
I
T
Q
Q
Q
P
A
EPT--------------------------------------------------------------------------------------------------------
68
HHSearch
86.32
35%
-83
- C3 -
1XKN
2
?
A:
[2-346]
--------
S
E
P
T
Y
F
M
-
P
P
E
W
A
P
H
A
S
T
W
L
S
W
P
H
K
L
----
E
-----
S
----------
W
P
--
G
K
F
E
P
V
P
A
V
F
A
E
L
A
Y
Q
L
S
R
-
S
E
T
V
N
I
-
N
V
-
L
D
D
A
-------
M
E
A
----
Q
A
-
R
-------------------------------------
E
L
L
K
E
R
D
P
EG
K
Y
---------
A
E
------
R
-------------------------
I
V
F
H
------------
R
I
P
-
T
-
N
D
A
W
C
R
D
H
G
P
N
Y
V
I
R
T
-
Q
DG
R
R
D
-
K
V
I
---
M
N
W
E
Y
N
A
W
G
G
K
----
Y
E
P
Y
D
D
D
N
A
V
P
E
R
V
A
K
A
------
Q
-
G
-----
L
P
M
V
------
S
---
T
G
M
-
V
L
E
G
G
A
I
D
V
N
G
A
G
L
L
L
T
T
T
A
C
L
L
N
P
N
R
N
P
S
L
-
G
K
A
E
I
E
A
Q
L
R
R
Y
L
------
G
----
I
--
E
K
--
V
L
W
L
G
D
G
-
I
A
G
--
D
-
D
-
T
D
G
H
V
D
D
-
M
A
R
F
V
N
E
N
T
V
V
I
A
V
E
E
D
P
E
D
-
E
---------
N
--
Y
K
P
-----
L
------------
R
E
N
Y
E
L
L
K
T
M
T
G
L
D
G
-
K
P
L
N
I
V
K
L
P
M
P
E
-
P
V
Y
------------------
Y
D
G
E
R
L
P
A
S
Y
A
N
F
Y
I
A
N
-
T
V
V
L
V
P
T
Y
R
-
C
P
-
R
-
D
Q
Q
A
I
D
I
L
Q
Q
C
F
P
K
R
E
V
V
G
I
-
D
-
C
S
D
L
I
--
W
G
L
G
A
I
H
C
V
T
H
E
E
P
A
-----------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
85.32
32%
-95
- C3 -
1XKN
2
?
A:
[6-345]
------------
Y
F
M
-
P
P
E
W
A
P
H
A
S
T
W
L
S
W
P
H
K
L
----
E
-----
S
----------
W
P
--
G
K
F
E
P
V
P
A
V
F
A
E
L
A
Y
Q
L
S
R
-
S
E
T
V
N
I
N
V
L
-
D
D
A
M
-------
E
-
A
----
Q
A
-
R
-------------------------------------
E
---------
L
L
K
E
R
D
P
EGKY
A
E
------
R
-------------------------
I
V
F
H
------------
R
I
P
-
T
-
N
D
A
W
C
R
D
H
G
P
N
Y
V
I
R
T
-
Q
---
D
G
-
R
R
D
K
V
I
M
N
W
E
Y
N
A
W
G
G
K
----
Y
E
P
Y
D
D
D
N
A
V
P
E
R
V
A
K
A
------
Q
-
G
-----
L
P
M
V
------
S
--
T
G
-
M
-
V
L
E
G
G
A
I
D
V
N
G
A
G
L
L
L
T
T
T
A
C
L
L
N
P
N
R
N
P
S
L
-
G
K
A
E
I
E
A
Q
L
R
R
Y
L
------
G
----
I
--
E
K
--
V
L
W
L
G
D
G
-
I
A
G
--
D
-
D
-
T
D
G
H
V
D
D
-
M
A
R
F
V
N
E
N
T
V
V
I
A
V
E
E
D
P
E
D
-
E
---------
N
--
Y
K
P
-----
L
------------
R
E
N
Y
E
L
L
K
T
M
T
G
L
D
G
-
K
P
L
N
I
V
K
L
P
M
P
E
-
P
V
Y
Y
------------------
D
G
E
R
L
P
A
S
Y
A
N
F
Y
I
A
N
-
T
V
V
L
V
P
T
Y
R
-
C
P
-
R
-
D
Q
Q
A
I
D
I
L
Q
Q
C
F
P
K
R
E
V
V
G
I
-
D
-
C
S
D
L
I
--
W
G
L
G
A
I
H
C
V
T
H
E
E
P
------------------------------------------------------------------------------------------------------------
70
HHSearch
79.86
29%
-79
- C3 -
3HVM
-
?
A:
[1-330]
-----------
M
K
R
M
-
L
A
E
F
E
K
I
Q
A
I
L
M
A
F
P
H
E
F
----
S
-----
D
----------
W
A
--
Y
C
I
K
E
A
R
E
S
F
L
N
I
I
Q
T
I
A
K
-
H
A
K
V
L
V
-
C
V
-
H
T
N
D
-------
T
-
I
G
Y
--
E
M
-
L
-----------------------------------------------
K
N
---------
L
P
------
G
-------------------------
V
E
I
A
------------
K
V
D
-
T
-
N
D
T
W
A
R
D
F
G
A
I
S
I
E
N
H
-----
G
V
-
L
E
C
---
L
D
F
G
F
N
G
W
G
L
K
Y
-----
P
S
N
L
D
N
Q
V
N
F
K
L
K
S
-------
L
-
G
FLK--
H
P
L
K
---------
T
M
P
Y
-
V
L
E
G
G
S
I
E
S
D
G
A
G
S
I
L
T
N
T
Q
C
L
L
E
K
N
R
N
P
H
L
-
N
Q
N
G
I
E
T
M
L
K
K
E
L
------
G
----
A
--
K
Q
--
V
L
W
Y
S
Y
G
Y
L
K
G
--
D
-
D
-
T
D
S
H
T
D
T
-
L
A
R
F
L
D
K
D
T
I
V
Y
S
A
C
E
D
K
N
D
-
E
---------
H
--
Y
T
A
-----
L
------------
K
K
M
Q
E
E
L
K
T
F
K
K
L
D
K
-
T
P
Y
K
L
I
P
L
E
I
P
K
-
A
I
F
D
-----------------
E
N
Q
Q
R
L
P
A
T
Y
V
N
F
L
L
C
N
-
D
A
L
I
V
P
T
Y
N
-
D
P
-
K
-
D
A
L
I
L
E
T
L
K
Q
H
T
P
-
L
E
V
I
G
V
-
D
-
C
N
T
L
I
--
K
Q
H
G
S
L
H
C
V
T
M
Q
L
Y
------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
79.69
28%
-83
- C3 -
3HVM
-
?
A:
[3-329]
-------------
R
M
-
L
A
E
F
E
K
I
Q
A
I
L
M
A
F
P
H
E
F
----
S
-----
D
----------
W
A
--
Y
C
I
K
E
A
R
E
S
F
L
N
I
I
Q
T
I
A
K
-
H
A
K
V
L
V
-
C
V
-
H
T
N
D
-------
T
-
I
----
G
Y
-
E
-----------------------------------------------
M
L
---------
K
N
------
L
PG-----------------------
V
E
I
A
------------
K
V
D
-
T
-
N
D
T
W
A
R
D
F
G
A
I
S
I
E
N
--
H
---
G
V
-
L
E
C
---
L
D
F
G
F
N
G
W
G
-----
L
K
Y
P
S
N
L
D
N
Q
V
N
F
K
L
K
S
L
------
G
F
L
-----
K
H
P
L
------
K
--
T
M
P
Y
-
V
L
E
G
G
S
I
E
S
D
G
A
G
S
I
L
T
N
T
Q
C
L
L
E
K
N
R
N
P
H
L
-
N
Q
N
G
I
E
T
M
L
K
K
E
L
------
G
----
A
--
K
Q
--
V
L
W
Y
S
Y
G
--
Y
L
K
G
D
-
D
-
T
D
S
H
T
D
T
-
L
A
R
F
L
D
K
D
T
I
V
Y
S
A
C
E
D
K
N
D
-
E
---------
H
--
Y
T
A
-----
L
------------
K
K
M
Q
E
E
L
K
T
F
K
K
L
D
K
-
T
P
Y
K
L
I
P
L
E
I
P
K
-
A
I
F
-----------------
D
E
N
Q
Q
R
L
P
A
T
Y
V
N
F
L
L
C
N
-
D
A
L
I
V
P
T
Y
N
-
D
P
-
K
-
D
A
L
I
L
E
T
L
K
Q
H
T
P
-
L
E
V
I
G
V
-
D
-
C
N
T
L
I
--
K
Q
H
G
S
L
H
C
V
T
M
Q
L
-------------------------------------------------------------------------------------------------------------
82
Fugue
71.37
22%
-74
- C3 -
4YTB
13
PAD_PORGI
A:
[1-422]
-
A
F
Q
E
T
N
P
P
A
G
P
V
R
A
-
I
A
E
Y
E
R
S
A
A
V
L
V
R
Y
P
----------------------------------
F
G
I
P
M
E
L
I
K
E
L
A
K
-
N
D
K
V
I
T
-
I
V
A
S
E
S
Q
-------
K
-
N
----
T
V
-
I
-------------------------------------
T
---------
Q
Y
---------
T
Q
S
GVNLS
N
-------------------------
C
D
F
I
------------
I
A
K
-
T
-
D
S
Y
W
T
R
D
Y
T
G
W
F
A
M
Y
D
-
T
---
N
K
-
V
G
L
---
V
D
F
I
Y
N
R
P
----------
R
P
N
D
D
E
F
P
K
Y
E
A
Q
Y
------
L
-
G
-----
I
E
-
M
------
F
--
G
M
K
L
-
K
Q
T
G
G
N
Y
M
T
D
G
Y
G
S
A
V
Q
S
H
I
A
Y
T
---
E
N
S
S
L
-
S
Q
A
Q
V
N
Q
K
M
K
D
Y
L
------
G
----
I
--
T
H
--
H
D
V
V
--
Q
-
D
P
N
--
G
-
E
-
Y
I
N
H
V
D
C
-
W
G
K
Y
L
A
P
N
K
I
L
I
R
K
V
P
D
-
N
H
-
P
---------
Q
--
H
Q
A
-----
L
------------
E
D
M
A
A
Y
F
A
A
Q
T
C
A
W
G
-
T
K
Y
E
V
Y
R
A
L
A
T
N
-
E
---------------------------
Q
P
Y
T
N
S
L
I
L
N
-
N
R
V
F
V
P
V
N
G
P
A
S
-
V
-
D
N
D
A
L
N
V
Y
K
T
A
M
P
G
Y
E
I
I
G
V
-
K
-
G
A
S
G
T
PW
L
G
T
D
A
L
H
C
R
T
H
E
V
A
D
KGYL
Y
I
K
H
YPILGEQAGP
D
Y
K
I
E
A
D
V
V
S
CANATIS
P
V
Q
C
Y
Y
R
I
NGSG
S
F
K
A
A
D
M
T
MESTG
H
Y
T
Y
S
F
T
GLNKN
D
K
V
E
Y
Y
I
S
A
A
D
NSG
R
K
E
T
YPFIGEP
D
P
F
K
F
T
C
MNE
1
PsiBlast_PDB
61.93
56%
27
- C3 -
2EWO
-
AGUA_STRMU
A:
[4-367]
-
R
I
K
N
T
T
P
K
Q
D
G
F
R
M
-
P
G
E
F
E
K
Q
K
Q
I
W
M
L
W
P
W
R
N
----
D
-----
N
----------
W
R
--
L
G
A
K
P
A
Q
K
A
F
L
E
V
A
E
A
I
S
E
-
F
E
P
V
S
L
-
C
V
-
P
P
L
Q
-------
Y
-
E
----
N
A
-
L
-------------------------------------
A
---------
R
V
---------
S
E
L
GSH--
N
-------------------------
I
R
I
I
------------
E
M
T
-
N
-
D
D
A
W
I
R
D
C
G
P
T
F
L
V
N
D
-
K
---
G
D
-
L
R
A
---
V
D
W
E
F
N
A
W
G
G
L
V
D
G
L
Y
F
P
W
D
Q
D
A
L
V
A
R
K
V
C
E
I
------
E
-
G
-----
V
D
S
Y
------
K
--
T
K
D
F
-
V
L
E
G
G
S
I
H
V
D
G
E
G
T
V
L
V
T
E
M
C
L
L
H
P
S
R
N
P
H
L
-
T
K
E
D
I
E
D
K
L
K
D
Y
L
------
N
----
C
--
V
K
--
V
L
W
V
K
D
G
-
I
D
P
--
Y
-
E
-
T
N
G
H
I
D
D
-
V
A
C
F
I
R
P
G
E
V
A
C
I
Y
T
D
D
K
E
H
-
P
---------
F
--
Y
Q
E
-----
A
------------
K
A
A
Y
D
F
L
S
Q
Q
T
D
A
K
G
-
R
P
L
K
V
H
K
M
C
V
T
K
E
P
C
Y
L
--
Q
E
A
A
T
I
D
Y
V
E
G
-------
E
M
A
I
A
S
Y
L
N
F
L
I
V
N
-
G
G
I
I
L
P
Q
Y
G
-
D
E
-
N
-
D
Q
L
A
K
Q
Q
V
Q
E
M
F
P
D
R
K
V
V
G
V
-
R
-
T
E
E
I
A
--
Y
G
G
G
N
I
H
C
I
T
Q
Q
Q
P
------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
61.52
23%
-66
- C3 -
4YTB
10
PAD_PORGI
A:
[47-313]
----------------------------------------------------------------------------------
I
T
I
-
V
A
-
S
E
S
Q
K
N
T
V
I
T
Q
Y
-
T
----
Q
S
-
G
-------------------------------------
V
---------
N
L
---------
S
N
--------------------------------
C
D
F
I
------------
I
A
K
-
T
-
D
S
Y
W
T
R
D
Y
T
G
W
F
A
M
Y
D
-
T
---
N
K
-
V
G
L
---
V
D
F
I
Y
N
R
----------
P
R
P
N
D
D
E
F
P
K
Y
E
A
Q
Y
------
L
-
G
-----
I
E
M
F
------
G
--
M
-
K
L
-
K
Q
T
G
G
N
Y
M
T
D
G
Y
G
S
A
V
Q
S
H
---
I
A
Y
T
E
N
S
S
L
-
S
Q
A
Q
V
N
Q
K
M
K
D
Y
L
------
G
----
I
--
T
H
HD
V
V
Q
D
P
N
G
-
E
Y
I
--
N
------
H
V
D
C
-
W
G
K
Y
L
A
P
N
K
I
L
I
R
K
V
P
D
N
-
H
-
P
---------
Q
--
H
Q
A
-----
L
------------
E
D
M
A
A
Y
F
A
A
Q
T
C
A
W
G
-
T
K
Y
E
V
Y
R
-------
A
L
A
T
N
E
Q
---------------------
P
Y
T
N
S
L
I
L
N
-
N
R
V
F
V
P
V
N
G
-
P
A
-
S
V
D
N
D
A
L
N
V
Y
K
T
A
M
P
G
Y
E
I
I
G
V
-
K
-
G
A
S
G
T
PW
L
G
T
D
A
L
H
C
R
T
H
E
V
-------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
61.44
23%
-62
- C3 -
5AK7
18
?
A:
[44-310]
----------------------------------------------------------------------------------
I
T
I
-
V
A
-
S
E
S
Q
K
N
T
V
I
T
Q
Y
-
T
----
Q
S
-
G
-------------------------------------
V
---------
N
L
---------
S
N
--------------------------------
C
D
F
I
------------
I
A
K
-
T
-
D
S
Y
W
T
R
D
Y
T
G
W
F
A
M
Y
D
-
T
---
N
K
-
V
G
L
---
V
D
F
I
Y
N
R
----------
P
R
P
N
D
D
E
F
P
K
Y
E
A
Q
Y
------
L
-
G
-----
I
E
M
F
------
G
--
M
-
K
L
-
K
Q
T
G
G
N
Y
M
T
D
G
Y
G
S
A
V
Q
S
H
---
I
A
Y
T
E
N
S
S
L
-
S
Q
A
Q
V
N
Q
K
M
K
D
Y
L
------
G
----
I
TH
H
D
--
V
V
Q
D
P
N
G
-
E
Y
I
--
N
------
H
V
D
C
-
W
G
K
Y
L
A
P
N
K
I
L
I
R
K
V
P
D
N
-
H
-
P
---------
Q
--
H
Q
A
-----
L
------------
E
D
M
A
A
Y
F
A
A
Q
T
C
A
W
G
-
T
K
Y
E
V
Y
R
-------
A
L
A
T
N
E
Q
---------------------
P
Y
T
N
S
L
I
L
N
-
N
R
V
F
V
P
V
N
G
-
P
A
-
S
V
D
N
D
A
L
N
V
Y
K
T
A
M
P
G
Y
E
I
I
G
V
-
K
-
G
A
S
G
T
P
W
L
G
T
D
A
L
H
C
R
T
H
E
V
-------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
61.33
22%
-65
- C3 -
4YTG
9
PAD_PORGI
A:
[47-316]
----------------------------------------------------------------------------------
I
T
I
-
V
A
-
S
E
S
Q
K
N
T
V
I
T
Q
Y
-
T
----
Q
S
-
G
-------------------------------------
V
---------