@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo2443: (2016-04-03 )
MYRLLSIAFFGIAVICLLFPWMSSGIDAATFELVYEPAYKLIWMQPIIIVGYLGFLCTIFIPKFQRGKNRIVPFIGILILVLGLLNLAVRPLFGFDSFNFSIIDAYVSELVEPAFLIAVSASILSLIMYAIYLKKSENL
Atome Classification :
(20 SA)
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.....-....10....-....20-........30........40--------.....----------------------------..-..50........60-...---------...---..70.....-...------80.....-...90...-..--...100...--....110--......------.120.....--..130.....------..---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MY
R
L
L
-
S
I
A
F
F
G
I
A
V
I
-
C
L
L
F
P
W
-
M
SSGID
A
A
T
F
E
L
V
YEPA
Y
K
---------
L
I
W
M
Q
----------------------------
P
I
-
I
I
V
G
Y
L
G
F
L
C
T
I
F
I
-
P
K
F---------QRG---KNR
I
V
P
F
I
G
-
I
L
I
------
L
V
L
G
L
L
N
-
L
A
V
R
PLFG-FD--SF
N
F
S
I
I
D
A
--
Y
V
S
E
LVE--
P
A
F
L
I
A
------
V
S
A
S
I
L
S
L
I
--
M
Y
A
I
Y
LKKSE------NL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38
Fugue
85.79
18%
-192
- C6 -
1AA7
-
M1_I34A1
A:
[1-158]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
S
L
L
T
-
E
V
E
T
Y
V
L
S
I
I
---------
P
S
G
P
L
K
A
E
I
A
Q
R
L
E
D
V
F
A
GKNTD
L
E
V
L
M
E
W
L
K
T
RPIL-----------------------
S
P
-
L
T
K
G
I
L
G
F
V
F
T
L
T
V
-
P
S
----------
E
R
G
---
L
Q
R
-
R
R
F
V
Q
-
N
A
L
NGNGD
P
N
N
M
D
K
A
V
-
K
L
Y
R
K
L
K
R
-
E
I
--
T
F
H
G
A
K
E
I
S
L
S
Y
S
A
G
A
L
A
--
S
C
M
G
L
I
Y
N
RM
G
A
V
T
T
E
V
A
F
G
L
--
V
C
A
T
C
E
Q
I
A
D
------
S
Q
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
Fugue
78.94
25%
-139
* C7 *
2JTD
-
A:
[1-122]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EEE
M
K
R
L
L
-
A
L
S
Q
E
H
K
-------
F
P
T
-
V
P
T
K
S
E
L
A
V
E
I
L
--
E
K
G
Q
V
---------
R
F
W
M
Q
----------------------------
A
E
-
K
L
S
S
N
A
K
V
S
Y
I
F
N
E
-
K
E
I
---------
F
E
G
PK
Y
K
M
H
I
D
R
N
T
G
-
I
I
E
------
M
F
M
E
K
L
Q
-
D
E
-----
D
-
E
G
--
T
Y
T
F
Q
I
Q
D
G
--
K
-------------
A
------
T
G
H
S
T
L
V
L
I
G
D
V
Y
K
K
L
Q
K
E
A
E
------
F
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
42
Fugue
75.56
18%
-134
- C7 -
1RPU
2
P19_CIRV
A:
[9-152]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D
T
R
E
Q
A
N
-
G
E
R
W
D
G
-------------
G
S
G
G
I
T
S
P
F
K
L
P
D
E
S
P
S
W
---------
T
E
W
R
L
Y
N
D
EN-----------------------
P
L
-
G
F
K
E
S
W
G
F
G
K
V
V
F
K
-
R
Y
L
---------
R
Y
D
---
R
T
E
A
S
L
H
R
V
-
L
G
S
------
W
T
G
D
S
V
N
-
Y
A
A
S
R
F
L
G
-
A
N
Q
V
G
C
T
Y
S
I
R
F
R
--
G
V
S
V
T
I
S
--
G
G
-----------
S
R
T
L
Q
H
L
C
--
E
M
A
I
R
S
K
Q
E
L
L
Q
LTPV
E
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
Fugue
75.46
22%
-150
* C5 *
4XGC
-
?
D:
[5-457]
D
R
E
L
V
S
I
R
R
F
L
K
E
R
L
Q
RDYTTLRGY
A
K
E
R
S
N
V
R
L
L
L
Q
R
T
A
E
MG
E
S
N
S
L
L
L
L
G
P
RGSG
K
T
T
L
I
N
S
V
L
A
D
L
L
P
NK
S
F
G
E
N
T
L
I
V
H
L
D
GNLHTD
D
R
V
A
L
K
S
I
T
V
Q
M
QLENAADGKVFGS
F
A
E
N
L
A
F
L
L
Q
C
L
KS
K
S
V
I
F
I
L
E
E
F
D
L
F
C
A
HHNQ
T
L
L
Y
N
L
F
D
V
S
Q
S
AQ
A
P
I
C
V
L
G
V
T
CRLDVIELLE
K
R
V
K
S
R
FSHRQ
V
F
L
F
PSLRR
F
E
D
Y
V
D
L
C
R
D
L
L
S
L
P
T
G
N
S
L
L
L
A
A
E
K
I
Y
N
L
Q
N
IQSGALYFSRNHFDPGE
Y
G
F
S
P
R
L
R
D
A
W
N
K
Q
I
C
K
V
L
A
T
Q
Q
A
R
S
T
L
Q
-
A
L
H
D
F
D
I
S
---------------
E
A
Y
L
K
N
F
L
F
R
L
V
A
H
---------
L
R
P
Q
S
----------------------------
P
H
-
I
T
A
E
K
M
A
A
V
G
S
Q
F
E
-
G
------------
D
D
---
K
I
E
L
L
C
G
L
S
-
V
L
E
------
L
C
L
I
I
A
I
-
K
H
H
S
Q
I
Y
D
-
R
D
--
S
F
N
F
E
I
I
Y
A
--
R
F
S
K
F
A
K
--
V
S
-------------
T
T
M
Q
A
V
--
E
R
S
I
V
L
K
A
F
E
------
H
L
R
I
A
EL
I
M
P
L
TKVQKEF
E
M
H
K
L
ALT
Y
S
Q
I
H
H
C
M
Q
R
YQALPT
E
V
A
Q
W
A
QSS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
Fugue
60.45
16%
-140
* C6 *
4P79
2
CLD15_MOUSE
A:
[2-190]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
E
F
M
S
V
A
V
E
T
F
G
F
F
M
S
A
L
G
L
L
M
L
G
L
T
L
S
N
S
Y
W
R
V
S
T
N
T
I
F
E
---------
N
L
W
Y
S
C
A
T
D
SLG
V
S
N
C
W
D
FP
S
M
L
A
L
S
G
Y
V
Q
G
C
R
A
L
M
I
T
A
I
L
L
G
F
L
G
L
F
L
G
M
V
G
L
RATNVGNMD
L
S
K
---
K
A
K
L
L
A
I
A
G
-
T
L
H
------
I
L
A
G
A
C
G
M
V
A
I
-
S
W
Y
A
-
V
N
--
I
T
T
D
F
F
N
P
L
--
Y
A
G
T
K
Y
E
LG
P
A
L
Y
L
G
------
W
S
A
S
L
L
S
I
L
--
G
G
I
C
V
F
S
T
A
A
------
A
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
41
Fugue
58.71
17%
-118
- C5 -
4YCZ
-
?
B:
[66-928]
-----------------------------------------------------------------------------------------S
E
Y
R
Y
A
A
L
A
K
D
A
Y
QQ
M
G
T
A
PVTE
P
P
Q
V
I
L
G
T
E
D
L
L
S
R
L
Y
D
EKM
D
D
T
L
A
T
A
A
A
Q
L
A
A
L
W
R
E
H
V
D
ET
P
F
E
K
A
N
Y
L
A
N
L
A
L
Q
I
H
HP
L
P
Q
T
L
F
R
W
LNEYHMYGS
Q
V
D
D
I
L
R
H
RPSPACHSL
F
W
Q
A
V
F
I
A
LK
V
G
D
A
A
R
L
L
D
Q
AGWGHVYAYVN
V
Q
R
A
V
D
E
T
I
A
V
L
E
SCPT
L
F
R
V
R
A
R
G
L
L
E
H
L
R
R
F
A
E
GW
E
I
Y
E
N
L
-
N
I
V
F
D
I
V
L
-------------
G
Q
Q
G
A
I
L
E
A
A
Q
D
---------------
W
L
E
----------------------------
A
T
-
V
G
L
A
N
S
E
S
Y
L
D
R
L
A
-
R
A
F
---------
H
T
A
---
V
E
S
D
F
V
E
I
G
M
A
C
V
------
F
-----
E
-
D
N
I
K
G
V
I
G
L
L
R
--
G
W
S
L
P
I
A
A
A
--
V
A
E
I
A
S
L
--
G
K
W
L
E
V
------
D
G
I
K
D
S
T
L
V
--
Q
Y
A
Q
A
L
A
D
Y
E
------
G
L
SSVQDRDGW
E
L
S
I
S
V
L
G
RMPER
S
E
E
M
V
R
D
L
V
E
H
L
V
Q
Q
LHVDS
N
A
T
V
D
R
L
W
F
L
L
N
ELGM
I
E
F
A
E
D
T
T
E
T
Y
G
D
I
L
ARDSHR
Y
G
E
A
M
W
Y
Y
A
L
AHR
P
N
K
V
R
E
V
M
N
L
L
T
S
Y
S
L
I
QPPAND
L
D
D
Y
L
Y
K
LLNDRK
N
T
L
E
Q
C
A
S
QDMEA
A
E
L
L
G
K
M
L
S
G
Y
A
S
L
R
Q
F
Y
D
I
RPH
A
T
P
L
S
R
R
K
Q
A
A
T
A
L
I
S
V
I
A
S
SDDEDF
L
L
A
L
L
G
E
A
L
V
F
V
SDPT
L
D
Q
I
D
V
L
L
K
A
I
E
D
L
Q
A
VGSR
V
Y
N
A
C
D
E
F
L
Q
L
V
L
ASAPGG
S
S
L
V
A
S
Q
L
Q
R
S
L
SGTGG
E
D
I
M
R
R
L
R
L
G
L
A
K
D
L
A
G
LWLAEA
34
Fugue
52.63
11%
-163
* C9 *
2NSC
-
TIG_THEMA
A:
[1-109]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
E
V
K
E
-
L
E
R
D
K
N
R
V
V
L
-
E
Y
V
F
G
--------
A
E
E
I
A
Q
A
E
D
K
A
V
R
---------
Y
L
N
Q
R
------------------------------------------
V
E
I
-
P
G
F
---------
R
K
G
---
R
---
I
P
K
N
V
-
L
K
M
------
K
L
G
E
E
F
Q
-
E
Y
T
L
D
F
L
M
--
D
--
L
I
P
D
T
L
K
D
R
--
K
L
I
L
S
P
I
--
V
T
E
R
E
L
------
K
D
V
T
--------
A
R
V
V
V
E
V
H
E
------
E
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
52.62
40%
-83
- C8 -
2PD0
1
?
B:
[57-88]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
I
E
N
N
----------------------------
P
T
-
L
V
D
G
Y
A
D
F
C
K
H
I
F
I
-
P
N
F
---------
T
E
A
---
K
Q
S
I
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
39
Fugue
52.48
9%
-154
- C7 -
3HF5
2
?
A:
[2-116]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
F
E
K
I
-
E
G
R
M
I
R
I
L
Y
L
-
L
V
-----
K
P
E
S
M
S
H
E
Q
F
R
K
E
C
V
V
H
F
Q
---------
M
S
A
G
M
----------------------------
P
-----
G
L
H
K
Y
E
V
R
L
V
A
-
G
N
P
---------
T
D
T
---
H
V
P
-----------------
Y
L
D
V
G
R
-
I
D
A
I
G
E
C
W
-
F
A
--
S
------
E
E
--
Q
Y
Q
V
Y
M
E
--
S
D
I
R
K
A
------
W
F
E
H
G
K
Y
F
I
--
G
Q
L
K
P
F
V
T
E
E
------
L
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
50.66
40%
-86
- C8 -
2PD0
1
?
A:
[57-88]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
I
E
N
N
----------------------------
P
T
-
L
V
D
G
Y
A
D
F
C
K
H
I
F
I
-
P
N
F
---------
T
E
A
---
K
Q
S
I
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
50.11
40%
-71
- C8 -
2PD0
1
?
D:
[57-89]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
I
E
N
N
----------------------------
P
T
-
L
V
D
G
Y
A
D
F
C
K
H
I
F
I
-
P
N
F
---------
T
E
A
---
K
Q
S
I
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
49.21
53%
-41
- C10 -
4N4Y
2
COX1_THET8
A:
[31-61]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
V
L
G
F
L
A
-
L
I
V
G
S
L
F
G
P
F
Q
--
A
L
N
Y
G
N
V
D
A
--
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
49.03
53%
-36
- C10 -
4FAA
1
COX1_THET8
A:
[31-73]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
V
L
G
F
L
A
-
L
I
V
G
S
L
F
G
P
F
Q
--
A
L
N
Y
G
N
V
D
A
--
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
48.13
53%
-35
- C10 -
3S3D
1
COX1_THET8
A:
[31-58]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
V
L
G
F
L
A
-
L
I
V
G
S
L
F
G
P
F
Q
--
A
L
N
Y
G
N
V
D
A
--
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
Fugue
47.30
14%
-64
- C9 -
4V0C
1
KCNQ1_HUMAN
A:
[7-108]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
H
H
H
H
G
S
D
Y
D
D
I
F
T
T
E
S
A
---------
L
---------------------------------------------
K
V
Q
Q
-
K
Q
R
---------
Q
K
H
---
F
N
R
Q
I
P
A
A
A
-
S
L
I
------
Q
T
A
W
R
C
Y
-
A
A
E
N
P
----------
D
S
S
T
W
K
I
--
Y
I
E
F
S
Q
L
--
R
E
H
H
R
A
------
T
I
K
V
I
R
R
M
Q
--
Y
F
V
A
K
K
K
F
Q
Q
------
A
R
KP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
47.19
53%
-40
- C10 -
3S3C
1
COX1_THET8
A:
[31-58]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
V
L
G
F
L
A
-
L
I
V
G
S
L
F
G
P
F
Q
--
A
L
N
Y
G
N
V
D
A
--
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
47.15
53%
-34
- C10 -
1EHK
1
COX1_THET8
A:
[25-57]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
V
L
G
F
L
A
-
L
I
V
G
S
L
F
G
P
F
Q
--
A
L
N
Y
G
N
V
D
A
--
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
47.03
53%
-39
- C10 -
3QJU
1
COX1_THET8
A:
[31-58]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
V
L
G
F
L
A
-
L
I
V
G
S
L
F
G
P
F
Q
--
A
L
N
Y
G
N
V
D
A
--
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
46.95
53%
-36
- C10 -
3QJR
1
COX1_THET8
A:
[31-58]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
V
L
G
F
L
A
-
L
I
V
G
S
L
F
G
P
F
Q
--
A
L
N
Y
G
N
V
D
A
--
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
46.88
53%
-39
- C10 -
4G7R
1
COX1_THET8
A:
[32-59]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
V
L
G
F
L
A
-
L
I
V
G
S
L
F
G
P
F
Q
--
A
L
N
Y
G
N
V
D
A
--
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------