@TOME V2.3
(Nov 2016)
Ref.
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs0777: (2015-12-03 )
MIKNSTLTKLTRVAILSALCVVLRYAFAPLPNIQPITAIFLITVVLFDLKEGVATVTITMLVSSFLMGFGPWVFLQIISFTLILCLWKFLIYPLTKAVCFGKITEVVLQTFFAGGLGVVYGVIIDTCFAWLYHMPWWTYVLAGLSFNMAHALSTCLFYPLLLPILRRFRNEKIH
Atome Classification :
(18 SA)
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10........20..----..-..-.-.30--.----...---.-...40...--------.------....50.-.-..---..-..-60.....---------------------..-.------------------------------------70---------...-----......80..--......90----..----.....-..100......----.110-----.........120---....-----.-------...130...------.-------....140---.---....-....-150..--------.....160........170..---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MIKN
S
T
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V
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----
R
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-AF-A-PLP--N----I
Q
P
---
I
-
T
A
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F
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T
V
--------
V
------
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F
D
L
KEG-
V
-
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---
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F
L
---------------------
M
G-F------------------------------------
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--
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A
-
V
C
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I
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E
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----
Q
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-------
F
FAG
G
L
G
V
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Y
G
----
V
I
I
D
-----
T
-------
C
F
A
W
L
-YHM------
P
-------
W
W
T
Y
V
-----
L
---
A
GLS-
F
N
M
A
-
H
A
L
S
T
--------
C
L
F
Y
P
L
-
L
L
P
I
L
R
R
F
RNEKIH---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
Fugue
83.82
18%
-196
- C7 -
4ART
4
Y273_ATV
A:
[22-270]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I
D
A
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N
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---
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-
Y
A
F
V
E
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V
--------
T
RD
F
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E
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F
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Y
G
-
L
-
P
S
---
I
S
-
D
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E
K
---------------------
A
G
-
F
------------------------------------
R
I
ANEVPTPNL
K
Y
Y
-----
I
H
A
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E
F
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--
L
A
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N
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-----
I
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----
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-
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GNKP
R
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-------
I
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F
N
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----
I
V
A
E
-----
E
QPILAGY
T
Y
D
E
A
-
L
R
I
------
P
-------
Y
H
Y
Y
V
DHNNS
F
---
K
D
D
A
-
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-
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A
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LFPTPY
Q
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R
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K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
Fugue
75.11
17%
-163
- C7 -
4HZU
-
?
S:
[1-164]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
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--
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TKGI
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---
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I
------
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---
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-
Y
------------------------------------
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----------
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-----
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--
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-----
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-------
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----
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-------
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-----
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-------
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-------------------
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W
P
A
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-----
L
---
A
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-
G
N
V
V
-
Q
V
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--------
A
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D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
Fugue
73.94
17%
-172
- C7 -
3RLB
8
?
A:
[17-192]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
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--
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----
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---
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--------
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-
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---
L
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-
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G
-
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---------------------
M
I
-
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------------------------------------
G
----------
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-----
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-------
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F
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----
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A
-----
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-------
I
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-
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A
------
W
K------
G
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A
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-----
A
---
Y
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A
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--------
A
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F
I
HSNY-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
Fugue
70.33
9%
-174
- C7 -
4NQ0
-
HIF1_YEAST
A:
[13-346]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T
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---
K
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A
NFSPANEHDDEIEDVSQLRK
S
G
-
F
------------------------------------
H
----------
I
Y
F
-----
E
N
D
L
Y
E
N
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--
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-----
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RPT
A
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----
V
Y
-------
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M
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-----
A
-------
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Y
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-
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------
G
-------
Y
Y
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-
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-----
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---
K
P
A
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A
--------
E
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C
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S
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Q
E
NQQH-------------------------------------------------------------------------------------------------------------------------------------------
19
Fugue
70.10
23%
-164
- C4 -
4L4W
-
?
A:
[1-267]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHMGPN
A
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E
L
T
T
D
Q
A
W
C
L
A
D
V
L
GAGSYPWVL
A
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P
Y
S
D
H
S
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A
F
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A
A
Q
S
A
E
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----
T
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M
G
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-
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N
S
A
--
G
A---
V
D
P
---
R
-
V
A
Q
W
I
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C
R
AT
Q
W
L
D
L
------
R
F
V
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L
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M
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-
A
R
R
SE
E
T
-
V
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A
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R
N
A
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L
---------------------
V
T
-
F
T
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M
DIGHQHAL
V
P
V
L
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A
GLSGR
K
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D
FALP
A
A
A
G
----------
A
R
A
-----
D
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A
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--
A
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GVPPS
A
R
----
P
L
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-
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R
T
Y
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E
I
----
V
A
-------
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I
I
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-------
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I
-
L
V
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------
P
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K
A
FDG
E
W
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F
-----
T
---
P
G
S
A
-
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A
I
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A
-------------------
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S
W
F
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
Fugue
68.59
14%
-180
- C7 -
1VK9
7
?
A:
[2-148]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GSDK
I
H
H
H
H
H
H
V
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K
N
L
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SGR
S
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-
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--
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----
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K
P
---
V
-
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R
-----------------
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-
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A
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------------------------------------
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A
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D
---------------------------------------------------------------
G
K
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M
C
P
F
E
-
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L
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M-------
D
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I
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F
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
Fugue
67.99
23%
-91
* C7 *
4OUA
8
?
B:
[4-557]
LLATVGPTGGVKNRLDIVDFVRDEKFFTLYIRALQAIQDKDQSDYSSFFQLSGIHGLPFTPWAKPKDTPTVPYESGYCTHSQVLFPTWHRVYVSIYEQILQEAAKGIAKKFTVHKKEWAQAAEDLRQPYWDTGFALVPPDEIIKLEQVKITNYDGTKITVRNPILRYSFHPIDPSFNGYPNFDTWKTTVRNPDADKKENIPALIGKLD
L
E
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------
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---
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M
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A
A
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F
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P
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W
L
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N
V
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--
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------
Y
----
P
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G
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W
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Q
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E
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G
S
M
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A
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T
E
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N
KDSAL
E
-------
P
F
Y
E
T
-
E
D
K
------
P
-------
W
T
S
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P
-----
L
TDT
A
L
L
N
-
Y
S
Y
P
-
D
F
D
K
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--------
K
G
G
T
P
----
D
L
V
R
D
Y
I
N
D
H
I
D
RRYGIKKSEGGKNPAQDLLSDFKGVTHDHNEDLKMFDWTIQASWKKFELDDSFAIIFYFAADGSTNVTKENYIGSINIFRGTTPTNCANCRTQDNLVQEGFVHLDRFIARDLDTFDPQAVHRYLKEKKLSYKVVADDHSVTLKSLRIRVQGRPLHLPPGVSFPRLDKNIPIVNFDDVLDLVTG
3
HHSearch
56.39
8%
-165
- C7 -
3RLB
8
?
A:
[17-191]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
V
R
L
L
T
E
I
A
F
M
A
A
L
A
F
I
I
----
S
L
-
I
P
N
T
-
V
Y
G
WI
I
----
V
E
I
---
A
-
C
I
P
I
L
L
L
S
--------
L
------
R
R
G
L
T
A
G
-
L
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V
G
---
G
L
-
I
W
-
G
I
L
S
-
M
I
---------------------
T
G
-
H
A-----------------------------------
Y
----------
I
L
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S
Q
A
F
L
E
Y
L
V
A
P
V
S
L
--
G
I
-
A
G
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-----
R
Q
----
K
T
A
P
---------
L
K
L
A
----
P
V
-------
L
L
G
T
F
V
A
V
L
L
K
----
Y
F
F
H
-----
F
-------
I
A
G
I
I
F
W
S
Q
YAWKGW
G
A
------
V
A
Y
S
L
-----
A
---
V
N
G
I
-
S
G
I
L
-
T
A
I
A
A
--------
F
V
I
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-
F
V
K
K
F
P
K
L
F
I
H
S
N
Y
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
Fugue
51.16
24%
-153
- C5 -
2KSS
-
CARS_MYXXA
A:
[21-106]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
I
Q
D
P
S
L
I
--
I
C
-----------
H
----
D
V
D
G
A
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I
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A
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P
----
H
S
EDGTISQ
R
F
L
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I
V
V
G
----
L
V
F
D
-----
D
-------
P
A
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Q
Y
-
P
D
D
------
P
-------
L
I
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-----
V
---
E
G
L
G
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--------
E
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E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
Fugue
50.95
12%
-133
- C6 -
2F3J
-
ALRF2_MOUSE
A:
[1-158]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
A
D
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M
D
M
S
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L
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D
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I
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N
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V
----
N
R
-
G
G
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G
-
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R
R
--
N
----
R
P
A
---
I
A
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G
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N
R
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A
--------
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------
Y
S
R
P
K
P
L
-
P
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K
---
W
Q
-
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L
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---------------------
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G
-
E
------------------------------------
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G
A
K
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--
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-----
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----
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---
F
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A
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----
D
Y
-------
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R
S
G
R
-------------
S
-----
L
-------
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A
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V
-
H
F
E
------
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-------
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-----
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---
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M
K
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P
L
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R
--------
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M
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-----
A
S
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E
H
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
HHSearch
46.17
10%
-152
- C8 -
2KSF
-
KDPD_ECOLI
A:
[398-463]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
I
Q
G
S
V
V
A
A
A
L
S
A
V
I
T
L
I
----
A
M
-
Q
W
-
L
M
A
F
D
--
A
----
A
N
L
V
M
L
Y
-
L
L
G
V
V
V
V
A
--------
L
------
F
Y
G
R
W
P
S
-
V
-
V
A
---
T
V
-
I
N
-
V
V
S
F
D
L
F
---------------------
F
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
44.30
34%
-47
- C8 -
3E9M
-
?
A:
[130-182]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
T
Q
K
V
K
----
A
T
-------
I
Q
E
G
G
L
G
E
I
L
W
----
V
Q
S
V
-----
T
-------
A
Y
P
N
V
-
D
H
I
------
P
-------
W
F
Y
S
R
-----
E
---
A
G
------
G
-
G
A
L
H
G
--------
S
G
S
Y
P
L
-
Q
Y
L
Q
Y
V
L
G
K
E
I
Q
E
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
HHSearch
39.49
23%
2
- C8 -
1KVD
-
TOXK_MILFA
A:
[22-47]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
--------
A
------
T
F
G
G
L
A
G
-
G
-
I
V
---
G
C
-
I
A
-
A
G
I
L
A
I
L
---------------------
Q
G
-
F
------------------------------------
E
----------
V
N
W
-----
H
N
G
G
G
G
D
R
S
N
--
P
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
25.34
6%
106
- C8 -
2WW9
-
SC61G_YEAST
B:
[60-75]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
V
G
I
I
G
Y
A
I
----
K
L
-
I
H
-
I
-
P
I
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
24.43
13%
606
- C1 -
3MP7
-
SECE_PYRFU
B:
[46-53]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
I
G
M
L
I
----
R
I
-
V
G
-
I
-
L
I
L
--
G
----
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
22.63
0%
193
* C8 *
2WWB
-
SC61G_CANFA
B:
[47-58]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
G
F
I
G
F
F
V
----
K
L
-
I
H
-
I
-
P
I
N
--
N
----
I
I
V
---
G
-
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
HHSearch
14.89
14%
755
- C3 -
1SMZ
-
?
A:
[7-13]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
G
--------
Y
------
L
L
G
K
I
N
L
-
K
-
A
L
---
A
A
-
L
A
-
K
K
I
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
5.62
33%
2515
- C2 -
3WU2
-
PSBI_THEVL
I:
[21-24]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
V
F
G
----
F
L
S
G
-----
D
-------
P
A
R
N
P
-
K
R
K
------
D
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------