@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs1962: (2015-12-12 )
MAKFGFLSVLEEELDKHLQYDFAMDWDKKNHTVEVTFILEAQNSSAIETVDDQGETSSEDIVFEDYVLFYNPVKSRFDAEDYLVTIPYEPKKGLSREFLAYFAETLNEVATEGLSDLMDFLTDDSIEEFGLSWDTDAFENGRAELKETEFYPYPRY
Atome Classification :
(20 SA)
------------..-....-...10....---.-.-.-.20.-----.......-------30..-----....----------..40----.........50......----..60-.-...--------....70..---......80.....---...90.......----------.100..------.....110....---------...120--.......130.......140...--...---..---150....----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
------------MA-K
F
G
F
-
L
S
V
L
E
E
E
L
D
---
K
-
H
-
L
-
Q
Y
DF-----AMDWDKK-------N
H
T
V
-----
E
V
T
F
----------
I
L
E-----AQNSSAIETVDDQGETS----SE
D
I
-
V
-
F
E
D
--------
Y
V
L
F
YN
P
V
---
K
SRFDAE
D
Y
L
V
TI---PYEPKKGL
S
R
E
F
----------
L
A
Y
F
A
E
------
T
L
N
E
V
A
T
E
G
L
S
D
---------
L
M
D
F
LT--DD
S
I
E
E
FGLSWDT
D
A
FEN-G
R
A
E--LKE---TE---FYPYPRY----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
98.77
46%
-124
- C3 -
3NAT
2
?
A:
[4-163]
------------
M
K
-
K
A
T
M
-
L
T
Y
L
E
E
Q
L
E
---
K
H
L
-
G
-
D
Y
E
V
-----
G
L
D
W
D
R
K
-------
N
H
T
I
-----
E
V
I
V
----------
R
L
Y
-----
A
E
N
N
E
Q
V
A
I
D
D
V
-----------
E
F
I
E
-
F
E
D
--------
G
L
L
F
Y
N
P
Q
---
K
S
V
V
D
D
E
E
Y
L
V
T
I
---
P
Y
E
G
K
K
G
L
R
K
A
V
----------
L
D
G
F
I
H
------
Y
L
K
V
V
L
D
E
G
Q
S
D
---------
L
L
D
F
L
S
--
D
E
T
A
E
V
F
E
L
H
W
E
P
A
D
F
E
A
-
M
I
K
K
--
V
A
E
T
E
K
E
Q
---
W
I
A
Y
P
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
98.13
47%
-129
- C3 -
3NAT
2
?
A:
[6-163]
---------------
K
A
T
M
-
L
T
Y
L
E
E
Q
L
E
---
K
-
H
-
L
G
D
Y
E
V
-----
G
L
D
W
D
R
K
-------
N
H
T
I
-----
E
V
I
V
----------
R
L
Y
-----
A
E
N
N
E
Q
V
A
I
D
D
V
-----------
E
F
-
I
E
F
E
D
--------
G
L
L
F
Y
N
P
Q
---
K
S
V
V
D
D
E
E
Y
L
V
T
I
---
P
Y
E
G
K
K
G
L
R
K
A
V
----------
L
D
G
F
I
H
------
Y
L
K
V
V
L
D
E
G
Q
S
D
---------
L
L
D
F
L
S
--
D
E
T
A
E
V
F
E
L
H
W
E
P
A
D
F
E
A
-
M
I
K
K
--
V
A
E
---
T
E
K
E
Q
W
I
A
Y
P
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
Fugue
96.59
46%
-121
- C3 -
3NAT
2
?
A:
[1-163]
-----------S
N
A
M
K
K
A
T
M
L
T
Y
L
E
E
Q
L
E
---
K
-
H
L
G
-
D
Y
E
V
-----
G
L
D
W
D
R
K
-------
N
H
T
I
-----
E
V
I
V
----------
R
L
Y
-----
A
E
N
N
E
Q
V
A
I
D
D
----------
V
E
F
I
-
E
-
F
E
D
--------
G
L
L
F
Y
N
P
Q
---
K
S
V
V
D
D
E
E
Y
L
V
T
I
---
P
Y
E
G
K
K
G
L
R
K
A
V
----------
L
D
G
F
I
H
------
Y
L
K
V
V
L
D
E
G
Q
S
D
---------
L
L
D
F
L
S
--
D
E
T
A
E
V
F
E
L
H
W
E
P
A
D
F
E
A
M
I
K
K
V
A
E
T
E
K
---
E
Q
---
W
I
A
Y
P
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
Fugue
54.82
19%
-32
* C4 *
2GX8
6
?
A:
[28-397]
------------
I
P
-
N
----
G
H
E
I
I
S
L
F
E
---
S
-
M
-
Y
-
P
K
H
L
-----
A
M
E
G
D
K
I
G
LQIGAL
N
K
P
V
-----
R
H
V
L
----------
I
A
L
-----
D
V
T
E
E
V
V
D
E
A
I
Q
L
G
A
--------
N
V
-
I
-
I
A
H
--------
H
P
L
I
F
N
P
L
---
K
A
I
H
T
D
K
A
Y
G
K
I
I
---
E
K
C
I
K
N
D
I
--------------
A
I
Y
A
A
H
------
T
N
V
D
V
A
K
G
G
----------------
V
N
--
D
L
L
A
E
A
L
G
L
Q
N
T
E
V
L
A
P
T
-
Y
A
E
E
--
M
K
K
---
V
V
---
V
F
V
P
V
T
H
A
E
E
V
R
K
A
L
G
D
A
GAGHIGNYSH
C
T
F
S
S
E
G
T
G
T
F
V
P
QQ
L
E
R
V
E
E
V
R
I
E
T
I
I
P
ASL
Q
R
K
V
I
K
A
M
V
T
A
HPYE
E
V
A
Y
D
V
Y
P
L
DNK
G
E
T
L
G
L
G
K
I
G
Y
L
Q
E
E
M
T
L
G
Q
F
A
E
H
V
K
Q
S
L
DVK
G
A
R
V
V
G
KLD
D
K
V
R
K
V
A
V
L
G
G
DGNKY
I
N
Q
A
K
F
K
GAD
V
Y
V
T
G
DMY
Y
H
V
A
H
D
A
M
M
L
G
L
N
I
V
D
PGHNVEK
V
M
K
Q
G
V
Q
K
Q
L
Q
E
K
V
D
A
K
KLN
V
H
I
H
A
SQLHTDPFIFV
39
Fugue
49.71
18%
-40
- C3 -
1JYO
-
SICP_SALTY
A:
[1-130]
-----------L
Q
A
-
H
Q
D
I
-
I
A
N
I
G
E
K
L
G
---
L
-
P
-
L
-
T
F
D
---------------------
D
N
N
-----
Q
C
L
L
----------
L
L
D
-----
S
D
I
F
T
S
I
E
A
K
D
D
-----------
I
W
-
L
-
L
N
G
--------
M
I
I
P
L
S
P
V
---
C
G
---------
D
S
---
I
W
R
Q
I
M
V
I
N
G
E
L
----------
A
A
N
N
E
G
------
T
L
A
Y
I
D
A
A
E
T
L
L
---------
L
I
H
A
I
T
--
D
L
T
-
N
T
Y
H
I
I
S
Q
L
E
S
F
V
N
-
Q
Q
E
A
--
L
K
N
---
I
----
L
Q
E
Y
A
K
V
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
Fugue
47.48
18%
-33
- C2 -
1Y88
10
Y1548_ARCFU
A:
[16-199]
NL
Y
F
Q
G
H
M
V
A
R
L
L
E
-
E
H
G
F
-
E
T
K
T
N
V
I
V
Q
GNC
V
-
E
-
Q
-
E
I
D
V
-----
V
A
E
R
D
G
E
-------
R
Y
M
I
-----
E
C
K
F
----------
H
N
I
-----
P
V
Y
T
G
L
K
E
A
M
Y
T
Y
A
R
F
L
----
D
V
E
K
-
H
G
F
T
Q
--------
P
W
I
F
T
N
T
K
F
S
E
E
A
K
K
Y
A
G
C
V
G
I
K
L
T
G
W
S
Y
P
E
K
E
G
I
E
V
L
L
E
S
K
GLYPITI
L
R
I
D
K
E
------
V
L
D
E
L
V
R
A
G
L
V
F
---------
C
R
D
V
V
S
A
G
E
E
K
L
R
E
I
G
L
S
--
A
K
K
A
R
E
-
V
I
A
E
--
A
K
K
---
V
I
---
G
G
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38
Fugue
45.66
17%
-22
- C4 -
3LNL
3
GCH1L_STAAM
B:
[1-370]
-----------A
M
D
-
P
M
K
--
I
A
D
L
M
T
L
L
D
---
H
-
H
-
V
-
P
F
S
T
-----
A
E
S
W
D
N
V
-------
G
L
L
I
GDEDV
E
V
T
G
----------
V
L
T
-----
A
L
D
C
T
--
L
E
V
V
N
E
A
I
E
K
----
G
Y
N
T
-
I
-
I
S
H
--------
H
P
L
I
F
K
G
V
---
T
S
L
K
A
N
G
-----
Y
---
G
L
I
I
R
K
L
I
Q
H
D
I
----------
N
L
I
A
M
H
------
T
N
L
D
V
N
P
H
G
----------------
V
N
--
M
M
L
A
K
V
M
G
L
K
N
I
S
I
I
N
N
Q
-
Q
D
V
Y
--
Y
K
V
---
Q
T
---
Y
I
P
K
D
N
V
G
P
F
K
D
K
L
S
E
N
GLAQEY
C
F
F
E
S
E
G
R
G
QED
V
D
E
V
K
I
E
F
M
I
D
AYQ
K
S
R
A
E
Q
L
I
K
Q
YHPYET
P
V
F
D
F
I
E
I
K
Q
TSLYGL
G
V
M
A
E
V
DNQMT
L
E
D
F
A
A
D
I
K
S
K
L
NIP
S
V
R
F
V
G
ESNQKIK
R
I
A
I
I
G
G
SGIGY
E
Y
Q
A
V
Q
Q
GAD
V
F
V
T
G
DIK
H
H
D
A
L
D
A
K
I
H
G
V
N
L
I
D
INHYSEY
V
M
K
E
G
L
K
T
L
L
M
N
W
F
N
I
E
KIN
I
D
V
E
A
STINTDPFQYI------------
8
PsiBlast_PDB
43.30
26%
-43
- C5 -
3WTZ
-
ETS1_HUMAN
A:
[26-87]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
G
T
F
K
D
Y
----------
V
R
D
---KDKP--
V
I
P
A
A
A
L
A
G
Y
T
G
SGPIQ
L
W
Q
F
L
L
E
L
L
T
--
D
K
S
C
Q
S
F
-
I
S
W
T
G
D
G
W
E
F
-
K
L
S
D
--
P
D
E
---
V
A
---
R
R
W
G
K
R
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
42.25
25%
-80
- C3 -
4A2A
1
?
A:
[63-149]
------------------
L
-
L
K
E
L
E
E
Q
L
Q
---
K
-
S
-
L
-
R
S
D
F
V
I
S
F
S
S
V
S
F
E
R
E
-------
D
T
V
I
-----
E
R
D
F
GE
E
K
R
S
IT
L
D
I
L
S
-----
E
M
Q
S
E
A
L
E
K
L
K
E
N
G
K
T
P
LHIF
S
K
R
Y
-
L
-
L
D
D
--------
E
R
I
V
F
N
P
L
---
D
M
K
A
S
K
I
A
I
E
Y
T
S
---
I
V
V
P
L
K
V
Y
E
M
F
Y
----------
N
F
L
Q
D
T
------
V
K
S
P
F
Q
L
K
S
S
L
V
---------
S
T
A
E
G
V
--
L
T
T
P
E
K
D
R
G
V
V
V
V
N
L
G
Y
N
-
F
T
G
L
--
I
A
Y
---
K
N
---
G
V
P
I
K
I
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
42.11
25%
-56
- C3 -
4A2B
1
?
A:
[63-149]
------------------
L
-
L
K
E
L
E
E
Q
L
Q
---
K
-
S
-
L
-
R
S
D
F
V
I
S
F
S
S
V
S
F
E
R
E
-------
D
T
V
I
-----
E
R
D
F
GE
E
K
R
S
I
T
L
D
I
L
S
-----
E
M
Q
S
E
A
L
E
K
L
K
E
N
G
K
T
P
L
H
I
F
S
K
R
Y
-
L
-
L
D
D
--------
E
R
I
V
F
N
P
L
---
D
M
K
A
S
K
I
A
I
E
Y
T
S
---
I
V
V
P
L
K
V
Y
E
M
F
Y
----------
N
F
L
Q
D
T
------
V
K
S
P
F
Q
L
K
S
S
L
V
---------
S
T
A
E
G
V
--
L
T
T
P
E
K
D
R
G
V
V
V
V
N
L
G
Y
N
-
F
T
G
L
--
I
A
Y
---
K
N
---
G
V
P
I
K
I
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
40.90
26%
-68
- C5 -
3RI4
2
ETS1_HUMAN
A:
[24-84]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
T
F
K
D
Y
----------
V
R
D
R
A
D
L
NKDKP
V
I
P
A
A
A
L
A
G
Y
T
G
SGPIQ
L
W
Q
F
L
L
E
L
L
T
--
D
K
S
C
Q
S
F
-
I
S
W
T
G
D
G
W
E
F
-
K
L
S
D
--
P
D
E
---
V
A
---
R
R
W
G
K
R
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
Fugue
40.78
13%
19
- C3 -
2KVO
-
PSB28_SYNY3
A:
[1-120]
------------
M
A
-
E
I
Q
F
-
S
K
G
V
A
E
T
V
V
---
P
-
E
-
V
-
R
L
S
K
-----
S
K
N
G
Q
S
G
-------
M
A
K
F
-----
Y
F
L
E
----------
P
T
I
LAKES
T
D
D
I
T
G
M
Y
L
I
D
D
E
G
E
I
I
----
T
R
E
V
-
K
-
G
K
F
--------
I
----------
N
G
R
P
T
A
I
E
A
T
V
I
L
---
N
S
Q
P
E
W
D
R
F
M
R
F
----------
M
E
R
Y
G
A
------
E
---------------------------------------------
N
-
G
L
G
F
--
S
K
S
---
E
L
---
E
H
H
H
H
H
H
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
39.94
26%
-57
- C5 -
3MFK
1
ETS1_HUMAN
A:
[23-83]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
T
F
K
D
Y
----------
V
R
D
R
A
D
LNKDKP
V
I
P
A
A
A
L
A
G
Y
T
G
SGPIQ
L
W
Q
F
L
L
E
L
L
T
--
D
K
S
C
Q
S
F
-
I
S
W
T
G
D
G
W
E
F
-
K
L
S
D
--
P
D
E
---
V
A
---
R
R
W
G
K
R
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
39.59
26%
-45
- C5 -
3WTT
2
ETS1_HUMAN
C:
[44-87]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------P-----
V
I
P
A
A
A
L
A
G
Y
T
G
SGPIQ
L
W
Q
F
L
L
E
L
L
T
--
D
K
S
C
Q
S
F
-
I
S
W
T
G
D
G
W
E
F
-
K
L
S
D
--
P
D
E
---
V
A
---
R
R
W
G
K
R
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
39.41
25%
-67
- C3 -
1E4F
-
?
T:
[63-149]
------------------
L
-
L
K
E
L
E
E
Q
L
Q
---
K
-
S
-
L
-
R
S
D
F
VISFS
S
V
S
F
E
R
E
-------
D
T
V
I
-----
E
R
D
F
GEEKRSITLD
I
L
S
-----
E
M
Q
S
E
A
L
E
K
L
K
E
N
G
K
T
P
LHIF
S
K
R
Y
-
L
-
L
D
D
--------
E
R
I
V
F
N
P
L
---
D
M
K
A
S
K
I
A
I
E
Y
T
S
---
I
V
V
P
L
K
V
Y
E
M
F
Y
----------
N
F
L
Q
D
T
------
V
K
S
P
F
Q
L
K
S
S
L
V
---------
S
T
A
E
G
V
--
L
T
T
P
E
K
D
R
G
V
V
V
V
N
L
G
Y
N
-
F
T
G
L
--
I
A
Y
---
K
N
---
G
V
P
I
K
I
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
38.81
26%
-52
- C5 -
3WU0
-
ETS1_HUMAN
A:
[26-87]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
G
T
F
K
D
Y
----------
V
R
D
R
A
D
L
N
K
D
K
P
V
I
P
A
A
A
L
A
G
Y
T
G
SGPIQ
L
W
Q
F
L
L
E
L
L
T
--
D
K
S
C
Q
S
F
-
I
S
W
T
G
D
G
W
E
F
-
K
L
S
D
--
P
D
E
---
V
A
---
R
R
W
G
K
R
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
38.73
26%
-35
- C5 -
3WTY
2
ETS1_HUMAN
C:
[44-87]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------P-----
V
I
P
A
A
A
L
A
G
Y
T
G
SPPIQ
L
W
Q
F
L
L
E
L
L
T
--
D
K
S
C
Q
S
F
-
I
S
W
T
G
D
G
W
E
F
-
K
L
S
D
--
P
D
E
---
V
A
---
R
R
W
G
K
R
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
38.50
26%
-37
* C5 *
2NNY
1
ETS1_HUMAN
A:
[38-92]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
R
D
R
A
D
LNKDKP
V
I
P
A
A
A
L
A
G
Y
T
G
SGPIQ
L
W
Q
F
L
L
E
L
L
T
--
D
K
S
S
Q
S
F
-
I
S
W
T
G
D
G
W
E
F
-
K
L
S
D
--
P
D
E
---
V
A
---
R
R
W
G
K
R
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
38.36
30%
-13
- C3 -
4C3H
-
RPAC2_YEAST
K:
[58-128]
---------------------------------------------------------------------------------------------------------
G
T
S
A
----
S
F
Q
I
-
V
-
E
E
D
HT
L
G
N
A
L
R
Y
V
I
M
K
N
P
--------
D
V
E
F
C
G
Y
S
I
---
P
H
P
S
E
N
L
L
N
I
R
I
----------
Q
T
Y
G
E
T
------
T
A
V
D
A
L
Q
K
G
L
K
D
---------
L
M
D
L
C
D
--
V
V
E
S
K
F
T
E
K
I
K
S
M
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
38.10
26%
-53
- C5 -
1MDM
-
ETS1_MOUSE
B:
[309-362]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
D
R
A
D
LNKDKP
V
I
P
A
A
A
L
A
G
Y
T
G
SGPIQ
L
W
Q
F
L
L
E
L
L
T
--
D
K
S
C
Q
S
F
-
I
S
W
T
G
D
G
W
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------