@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VLU6: (2017-11-04 )
MSGSTITPWVVGNWKMNPMRANANQLIEEFKQLLQQNQIADENCHVGVAPVSIALTTVQAQLQDAARTVYTVAQDVSRVAGTGAYTGEVSAELLKDSQINFVLVGHSERRDIFGDNVEILKAKLQNALNAGMTVIYCVGESLEQREQGQAEQVVLQQICDIAPVVTAEQWQNQVVIAYEPIWAIGTGKTASPQDAQAMHAKIREGLCQLTPAGSNIAILYGGSVKAENAVELAACPDINGALVGGASLNAASFYQIVQAFAQSK
Atome Classification :
(77 SA)
.........10........20........30--.--.......40..--......50--.....--..--..60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.---...-...--210..--.--....----..220.......230.......240.......250.......260..
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MSGS
T
I
T
P
W
V
VGN
W
K
MNPMRA
N
A
N
Q
L
I
E
E
F
K
--
Q
--
L
L
Q
QNQIADEN--CHV
G
V
A
P
---
V
S
I
A
L
--
T
T
--
V
Q
A
Q
L
Q
D
A
A
R
T
V
Y
T
V
A
Q
D
V
S
R
V
AGTGAYT
G
E
V
S
A
E
L
L
KDSQI
N
F
V
L
VGHS
E
R
R
D
IFGD
N
V
E
I
L
K
A
K
L
Q
N
A
L
NAG
M
T
V
I
Y
CVGE
S
L
E
Q
R
EQG
Q
A
E
Q
V
V
L
Q
Q
I
CDIAPVV
T
A
E
Q
WQN
Q
V
V
I
A
YE
P
I
W
A
IGTGKTASP
Q
D
A
Q
A
M
H
A
K
I
R
---
E
G
L
-
C
QL--T--PA--G--
S
N
I
A
----
I
L
YGGSVKAEN
A
V
E
L
AACPDIN
G
A
L
VGGASL
N
A
A
S
F
Y
Q
I
V
Q
A
F
AQSK
17
PsiBlast_PDB
89.19
43%
-96
- C7 -
-
4Y96
-
?
A:
[10-253]
--------
F
V
A
G
N
W
K
M
N
T
T
L
A
E
A
K
A
L
G
A
A
V
A
--
K
-------
G
V
T
D
D
R
--
V
T
V
A
V
F
P
---
P
Y
P
W
L
--
T
A
--
V
G
E
V
L
K
G
S
P
--
V
A
L
G
A
Q
D
V
S
S
-
E
K
K
G
A
F
T
G
E
V
S
P
A
M
L
L
E
T
G
C
K
Y
A
L
I
G
H
S
E
R
R
H
I
I
G
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S
E
T
F
I
N
H
K
V
H
T
A
L
E
E
G
L
S
V
V
L
C
M
G
E
T
L
A
E
R
E
R
G
L
Q
E
R
V
F
Q
R
Q
V
Y
A
A
C
A
G
L
T
D
E
Q
F
-
G
R
I
V
I
A
Y
E
P
V
W
A
I
G
T
G
K
V
A
T
P
E
Q
A
Q
E
A
H
A
F
V
R
---
S
K
L
-
R
L
L
--
Y
------
G
--
D
K
I
A
D
S
T
P
I
V
Y
G
G
S
V
T
P
D
N
T
V
G
L
M
S
Q
P
D
V
D
G
A
L
V
G
G
A
S
L
K
A
D
S
F
L
A
I
V
K
A
-----
131
HHSearch
88.35
43%
-89
- C7 -
-
4Y96
-
?
B:
[6-254]
----
T
R
K
K
F
V
A
G
N
W
K
M
N
T
T
L
A
E
A
K
A
L
G
A
A
V
A
--
K
--
G
V
-----
T
D
D
R
--
V
T
V
A
V
F
P
---
P
Y
P
W
L
--
T
A
--
V
G
E
V
L
K
--
G
S
P
V
A
L
G
A
Q
D
V
S
-
S
E
K
K
G
A
F
T
G
E
V
S
P
A
M
L
L
E
T
G
C
K
Y
A
L
I
G
H
S
E
R
R
H
I
I
G
E
S
E
T
F
I
N
H
K
V
H
T
A
L
E
E
G
L
S
V
V
L
C
M
G
E
T
L
A
E
R
E
R
G
L
Q
E
R
V
F
Q
R
Q
V
Y
A
A
C
A
G
L
T
D
E
Q
F
G
-
R
I
V
I
A
Y
E
P
V
W
A
I
G
T
G
K
V
A
T
P
E
Q
A
Q
E
A
H
A
F
V
R
---
S
K
L
-
R
L
L
--
Y
GD
K
I
--
A
--
D
S
T
P
----
I
V
Y
G
G
S
V
T
P
D
N
T
V
G
L
M
S
Q
P
D
V
D
G
A
L
V
G
G
A
S
L
K
A
D
S
F
L
A
I
V
K
A
A
----
8
PsiBlast_PDB
88.30
43%
-98
- C7 -
-
4GNJ
1
?
A:
[27-269]
-------
P
I
V
A
A
N
W
K
C
N
G
T
T
A
S
----
I
E
K
L
V
--
Q
--
V
L
N
E
H
Q
I
-
D
H
D
--
V
Q
C
V
V
A
P
---
S
F
V
H
I
--
P
M
--
V
Q
A
K
L
C
N
P
K
---
Y
A
V
S
A
E
-
N
A
I
A
K
S
G
A
F
T
G
E
V
S
M
P
I
L
K
D
L
G
V
S
W
V
I
L
G
H
S
E
R
R
T
Y
Y
G
E
T
D
G
V
V
A
Q
K
V
A
D
A
Y
N
Q
G
F
M
V
I
A
C
I
G
E
T
L
Q
Q
R
E
A
N
Q
T
A
K
V
V
L
S
Q
T
A
A
I
A
A
K
L
P
K
E
A
W
-
S
Q
I
V
L
A
Y
E
P
V
W
A
I
G
T
-
K
V
A
T
P
E
Q
A
Q
E
V
H
A
L
L
R
---
Q
W
V
-
S
E
K
--
I
--
G
N
--
G
V
A
T
K
L
R
----
I
L
Y
G
G
S
V
T
A
G
N
A
K
T
L
Y
M
K
P
D
I
N
G
F
L
V
G
G
A
S
L
K
-
P
E
F
R
D
I
I
D
A
-----
143
HHSearch
86.88
41%
-90
- C7 -
-
4MKN
6
?
A:
[17-267]
---
S
S
A
K
F
F
V
G
G
N
W
K
C
N
G
S
V
A
N
V
A
K
L
V
D
E
L
N
--
A
--
G
T
-----
I
P
R
G
--
V
D
V
V
V
A
P
---
P
F
I
Y
I
--
D
Y
--
V
M
Q
H
L
D
--
R
D
K
Y
Q
L
S
A
Q
N
A
W
-
I
G
G
N
G
A
F
T
G
E
V
S
A
E
Q
L
T
D
F
G
V
P
W
V
I
L
G
H
S
E
R
R
S
L
F
G
E
S
N
E
V
V
A
K
K
T
S
H
A
L
A
A
G
L
G
V
I
A
C
I
G
E
T
L
E
Q
R
N
S
G
S
V
F
K
V
L
D
A
Q
M
D
A
L
V
D
E
V
--
K
D
W
T
-
K
V
V
L
A
Y
E
P
V
W
A
I
G
T
G
V
V
A
S
P
E
Q
A
Q
E
V
H
A
Y
L
R
---
Q
Y
C
-
A
K
K
--
L
G
A
A
V
--
A
--
D
K
L
R
----
I
I
Y
G
G
S
V
S
D
T
N
C
K
D
L
S
K
Q
E
D
I
D
G
F
L
V
G
G
A
S
L
K
G
A
A
F
V
T
I
C
N
A
A
G
P
K
-
30
PsiBlast_CBE
86.74
43%
-104
- C7 -
-
4GNJ
2
?
B:
[27-269]
-------
P
I
V
A
A
N
W
K
C
N
G
T
T
A
S
----
I
E
K
L
V
--
Q
--
V
L
N
E
H
Q
I
-
D
H
D
--
V
Q
C
V
V
A
P
---
S
F
V
H
I
--
P
M
--
V
Q
A
K
L
C
N
P
K
---
Y
A
V
S
A
E
-
N
A
I
A
K
S
G
A
F
T
G
E
V
S
M
P
I
L
K
D
L
G
V
S
W
V
I
L
G
H
S
E
R
R
T
Y
Y
G
E
T
D
G
V
V
A
Q
K
V
A
D
A
Y
N
Q
G
F
M
V
I
A
C
I
G
E
T
L
Q
Q
R
E
A
N
Q
T
A
K
V
V
L
S
Q
T
A
A
I
A
A
K
L
P
K
E
A
W
-
S
Q
I
V
L
A
Y
E
P
V
W
A
I
G
--
K
V
A
T
P
E
Q
A
Q
E
V
H
A
L
L
R
---
Q
W
V
-
S
E
K
--
I
--
G
N
--
G
V
A
T
K
L
R
----
I
L
Y
G
G
S
V
T
A
G
N
A
K
T
L
Y
M
K
P
D
I
N
G
F
L
V
G
G
A
S
L
K
-
P
E
F
R
D
I
I
D
A
-----
142
HHSearch
86.68
42%
-91
- C7 -
-
4Y8F
-
TPIS_CLOPE
A:
[2-250]
--
S
H
M
R
T
P
I
I
A
G
N
W
K
M
H
Y
T
I
D
E
A
V
K
L
V
E
E
L
K
--
P
--
L
V
-----
K
D
A
K
--
C
E
V
V
V
C
P
---
T
F
V
C
L
--
D
A
--
V
K
K
A
V
E
--
G
T
N
I
K
V
G
A
Q
N
M
H
-
F
E
E
K
G
A
F
T
G
E
I
A
P
R
M
L
E
A
M
N
I
D
Y
V
I
I
G
H
S
E
R
R
E
Y
F
N
E
T
D
E
T
C
N
K
K
V
K
A
A
F
A
H
N
L
T
P
I
L
C
C
G
E
T
L
E
Q
R
E
N
G
T
T
N
D
V
I
K
A
Q
I
T
A
D
L
E
G
L
T
K
E
Q
A
E
-
K
V
V
I
A
Y
E
P
I
W
A
I
G
T
G
K
T
A
T
S
D
Q
A
N
E
T
I
A
A
I
R
---
A
M
V
-
A
E
M
--
F
G
Q
E
V
--
A
--
D
K
V
R
----
I
Q
Y
G
G
S
V
K
P
N
T
I
A
E
Q
M
A
K
S
D
I
D
G
A
L
V
G
G
A
S
L
V
A
A
D
F
A
Q
I
V
N
------
4
PsiBlast_PDB
86.68
45%
-93
- C7 -
-
4WJE
-
?
A:
[6-254]
------
T
F
F
V
G
G
N
W
K
A
N
P
K
T
V
---
Q
E
A
E
K
L
V
--
E
--
M
L
N
G
A
K
V
-
E
G
N
--
V
E
V
V
V
A
A
---
P
F
A
F
L
--
P
T
--
L
Q
Q
K
L
----
R
K
D
W
K
V
S
A
E
N
V
F
T
K
P
N
G
A
F
T
G
E
V
T
V
P
M
I
K
S
F
G
I
E
W
T
I
L
G
H
S
E
R
R
D
I
L
K
E
D
D
E
F
L
A
A
K
A
K
F
A
L
E
N
G
M
K
I
I
Y
C
C
G
E
H
L
S
E
R
E
A
G
K
A
S
E
F
V
S
A
Q
I
E
K
M
I
P
A
I
P
A
G
K
W
-
D
D
V
V
I
A
Y
E
P
I
W
A
I
G
T
G
K
V
A
S
T
Q
D
A
Q
E
M
C
K
V
I
R
---
D
I
L
-
A
----
A
--
K
V
--
G
--
A
D
I
A
N
K
V
R
I
L
Y
G
G
S
V
K
P
N
N
C
N
E
L
A
A
C
P
D
V
D
G
F
L
V
G
G
A
S
L
E
A
G
-
F
I
N
I
V
N
S
N
V
H
S
-
1
PsiBlast_PDB
86.32
45%
-91
- C7 -
-
3QST
-
?
A:
[6-255]
------
T
F
F
V
G
G
N
W
K
A
N
P
K
T
V
---
Q
E
A
E
K
L
V
--
E
--
M
L
N
G
A
K
V
-
E
G
N
--
V
E
V
V
V
A
A
---
P
F
V
F
L
--
P
T
--
L
Q
Q
K
L
----
R
K
D
W
K
V
S
A
E
N
V
F
T
K
P
N
G
A
F
T
G
E
V
T
V
P
M
I
K
S
F
G
I
E
W
T
I
L
G
H
S
E
R
R
D
I
L
K
E
D
D
E
F
L
A
A
K
A
K
F
A
L
E
N
G
M
K
I
I
Y
C
C
G
E
H
L
S
E
R
E
A
G
K
A
S
E
F
V
S
A
Q
I
E
K
M
I
P
A
I
P
A
G
K
W
-
D
D
V
V
I
A
Y
E
P
I
W
A
I
G
T
G
K
V
A
S
T
Q
D
A
Q
E
M
C
K
V
I
R
---
D
I
L
-
A
----
A
--
K
V
--
G
--
A
D
I
A
N
K
V
R
I
L
Y
G
G
S
V
K
P
N
N
C
N
E
L
A
A
C
P
D
V
D
G
F
L
V
G
G
A
S
L
E
A
G
-
F
I
N
I
V
N
S
N
V
H
S
K
48
PsiBlast_CBE
86.13
41%
-84
- C7 -
-
4MKN
6
?
A:
[17-263]
---
S
S
A
K
F
F
V
G
G
N
W
K
C
N
G
S
V
A
N
V
A
K
L
V
D
E
--------
L
N
A
G
T
I
P
-
R
G
--
V
D
V
V
V
A
P
---
P
F
I
Y
I
--
D
Y
--
V
M
Q
H
L
D
---
R
D
K
Y
Q
L
S
A
Q
N
A
W
I
G
G
N
G
A
F
T
G
E
V
S
A
E
Q
L
T
D
F
G
V
P
W
V
I
L
G
H
S
E
R
R
S
L
F
G
E
S
N
E
V
V
A
K
K
T
S
H
A
L
A
A
G
L
G
V
I
A
C
I
G
E
T
L
E
Q
R
N
S
G
S
V
F
K
V
L
D
A
Q
M
--
D
A
L
V
D
E
V
K
D
W
-
T
K
V
V
L
A
Y
E
P
V
W
A
I
G
T
G
V
V
A
S
P
E
Q
A
Q
E
V
H
A
Y
L
R
---
Q
Y
C
-
A
K
K
--
L
--
G
A
A
V
A
--
D
K
L
R
----
I
I
Y
G
G
S
V
S
D
T
N
C
K
D
L
S
K
Q
E
D
I
D
G
F
L
V
G
G
A
S
L
K
G
A
A
F
V
T
I
C
N
A
-----
136
HHSearch
85.94
40%
-98
- C7 -
-
1B9B
-
B:
[1-252]
---
I
T
R
K
L
I
L
A
G
N
W
K
M
H
K
T
I
S
E
A
K
K
F
V
S
L
L
V
--
N
--
E
L
H
----
D
V
K
E
--
F
E
I
V
V
C
P
---
P
F
T
A
L
--
S
E
--
V
G
E
I
L
S
--
G
R
N
I
K
L
G
A
Q
N
V
F
-
Y
E
D
Q
G
A
F
T
G
E
I
S
P
L
M
L
Q
E
I
G
V
E
Y
V
I
V
G
H
S
E
R
R
R
I
F
K
E
D
D
E
F
I
N
R
K
V
K
A
V
L
E
K
G
M
T
P
I
L
C
V
G
E
T
L
E
E
R
E
K
G
L
T
F
C
V
V
E
K
Q
V
R
E
G
F
Y
G
L
D
K
E
E
A
K
-
R
V
V
I
A
Y
E
P
V
W
A
I
G
T
G
R
V
A
T
P
Q
Q
A
Q
E
V
H
A
F
I
R
---
K
L
L
-
S
E
M
--
Y
D
E
E
T
--
A
--
G
S
I
R
----
I
L
Y
G
G
S
I
K
P
D
N
F
L
G
L
I
V
Q
K
D
I
D
G
G
L
V
G
G
A
S
L
K
E
-
S
F
I
E
L
A
R
I
M
R
G
--
29
PsiBlast_CBE
85.94
43%
-98
- C7 -
-
5CG7
1
?
B:
[27-269]
-------
P
I
V
A
A
N
W
K
C
N
G
T
T
A
S
----
I
E
K
L
V
--
Q
--
V
L
N
E
H
Q
I
-
D
H
D
--
V
Q
C
V
V
A
P
---
S
F
V
H
I
--
P
M
--
V
Q
A
K
L
N
P
K
----
Y
A
V
S
A
E
-
N
A
I
A
K
S
G
A
F
T
G
E
V
S
M
P
I
L
K
D
L
G
V
S
W
V
I
L
G
H
S
E
R
R
T
Y
Y
G
E
T
D
G
V
V
A
Q
K
V
A
D
A
Y
N
Q
G
F
M
V
I
A
C
I
G
E
T
L
Q
Q
R
E
A
N
Q
T
A
K
V
V
L
S
Q
T
A
A
I
A
A
K
L
P
K
E
A
W
-
S
Q
I
V
L
A
Y
E
P
V
W
A
I
---
K
V
A
T
P
E
Q
A
Q
E
V
H
A
L
L
R
---
Q
W
V
-
S
E
K
--
I
--
G
N
--
G
V
A
T
K
L
R
----
I
L
Y
G
G
S
V
T
A
G
N
A
K
T
L
Y
M
K
P
D
I
N
G
F
L
V
G
G
A
S
L
K
-
P
E
F
R
D
I
I
D
A
-----
152
Fugue
85.59
42%
-95
- C7 -
-
1TCD
-
TPIS_TRYCR
A:
[4-251]
----
K
P
Q
P
I
A
A
A
N
W
K
C
N
G
S
E
S
L
L
V
P
L
I
E
T
L
N
--
A
--
A
T
F
D
H
-----
D
--
V
Q
C
V
V
A
P
---
T
F
L
H
I
--
P
M
--
T
K
A
R
L
T
N
P
--
K
F
Q
I
A
A
Q
N
A
I
T
-
R
-
S
G
A
F
T
G
E
V
S
L
Q
I
L
K
D
Y
G
I
S
W
V
V
L
G
H
S
E
R
R
L
Y
Y
G
E
T
N
E
I
V
A
E
K
V
A
Q
A
C
A
A
G
F
H
V
I
V
C
V
G
E
T
N
E
E
R
E
A
G
R
T
A
A
V
V
L
T
Q
L
A
A
V
A
Q
K
L
S
K
E
A
W
S
R
-
V
V
I
A
Y
E
P
V
W
A
I
G
T
G
K
V
A
T
P
Q
Q
A
Q
E
V
H
E
L
L
R
---
R
W
V
-
R
S
K
LG
T
--
D
I
--
A
--
A
Q
L
R
----
I
L
Y
G
G
S
V
T
A
K
N
A
R
T
L
Y
Q
M
R
D
I
N
G
F
L
V
G
G
A
S
L
K
-
P
E
F
V
E
I
I
E
A
T
K
---
153
Fugue
85.34
42%
-91
- C7 -
-
1IF2
1
TPIS_LEIME
A:
[3-251]
---
A
K
P
Q
P
I
A
A
A
N
W
K
C
N
G
T
T
A
S
I
E
K
L
V
Q
V
F
N
--
E
--
H
T
-----
I
S
H
D
--
V
Q
C
V
V
A
P
---
T
F
V
H
I
--
P
L
--
V
Q
A
K
L
R
N
--
P
K
Y
V
I
S
A
Q
N
A
I
A
--
K
S
G
A
F
T
G
E
V
S
M
P
I
L
K
D
I
G
V
H
W
V
I
L
G
H
S
E
R
R
T
Y
Y
G
E
T
D
E
I
V
A
Q
K
V
S
E
A
C
K
Q
G
F
M
V
I
A
C
I
G
E
T
L
Q
Q
R
E
A
N
Q
T
A
K
V
V
L
S
Q
T
S
A
I
A
A
K
L
T
K
D
A
W
N
Q
-
V
V
L
A
Y
E
P
V
W
A
I
G
T
G
K
V
A
T
P
E
Q
A
Q
E
V
H
L
L
L
R
---
K
W
V
-
S
E
N
IG
T
--
D
V
--
A
--
A
K
L
R
----
I
L
Y
G
G
S
V
N
A
A
N
A
A
T
L
Y
A
K
P
D
I
N
G
F
L
V
G
G
A
S
L
K
P
-
E
F
R
D
I
I
D
A
T
R
---
16
PsiBlast_PDB
85.23
44%
-85
- C7 -
-
2BTM
1
TPIS_GEOSE
A:
[3-248]
-------
P
I
I
A
G
N
W
K
M
N
G
T
L
A
E
A
V
Q
F
V
E
D
V
K
--
G
--
H
V
P
P
---
A
D
E
V
--
I
S
V
V
C
A
P
---
F
L
F
L
D
--
R
L
--
V
Q
A
----
A
D
G
T
D
L
K
I
G
A
Q
T
M
H
F
A
D
Q
G
A
Y
T
G
E
V
S
P
V
M
L
K
D
L
G
V
T
Y
V
I
L
G
H
S
E
R
R
Q
M
F
A
E
T
D
E
T
V
N
K
K
V
L
A
A
F
T
R
G
L
I
P
I
I
C
C
G
E
S
L
E
E
R
E
A
G
Q
T
N
A
V
V
A
S
Q
V
E
K
A
L
A
G
L
T
P
E
Q
V
K
-
Q
A
V
I
A
Y
E
P
I
W
A
I
G
T
G
K
S
S
T
P
E
D
A
N
S
V
C
G
H
I
R
---
S
V
V
-
S
R
L
FG
P
--
E
A
--
A
--
E
A
I
R
----
I
Q
Y
G
G
S
V
K
P
D
N
I
R
D
F
L
A
Q
Q
Q
I
D
G
A
L
V
G
G
A
S
L
E
P
A
S
F
L
Q
L
V
E
A
-----
38
PsiBlast_CBE
85.15
42%
-105
- C7 -
-
4HHP
2
?
A:
[7-249]
-------
P
I
A
A
A
N
W
K
C
N
G
S
E
S
L
L
V
P
L
I
E
T
L
N
--
A
-------
A
T
F
D
H
D
--
V
Q
C
V
V
A
P
---
T
F
L
H
I
--
P
M
--
T
K
A
R
L
T
N
P
K
F
Q
I
--
A
A
Q
N
A
--
I
T
R
S
G
A
F
T
G
E
V
S
L
Q
I
L
K
D
Y
G
I
S
W
V
V
L
G
H
S
E
R
R
L
Y
Y
G
D
T
N
E
I
V
A
E
K
V
A
Q
A
C
A
A
G
F
H
V
I
V
C
V
G
E
T
N
E
E
R
E
A
G
R
T
A
A
V
V
L
T
Q
L
A
A
V
A
Q
K
L
S
K
E
A
W
-
S
R
V
V
I
A
Y
E
P
V
W
A
I
G
T
G
K
V
A
T
P
Q
Q
A
Q
E
V
H
E
L
L
R
---
R
W
V
---
R
--
S
--
K
L
--
G
--
T
D
I
A
A
Q
L
R
I
L
Y
G
G
S
V
T
A
K
N
A
R
T
L
Y
Q
M
R
D
I
N
G
F
L
V
G
G
A
S
L
K
-
P
E
F
V
E
I
I
E
A
-----
41
PsiBlast_CBE
84.68
41%
-101
- C7 -
-
1SUX
1
TPIS_TRYCR
A:
[7-249]
-------
P
I
A
A
A
N
W
K
C
N
G
S
E
S
L
L
V
P
L
I
E
T
L
N
--
A
-------
A
T
F
D
H
D
--
V
Q
C
V
V
A
P
---
T
F
L
H
I
--
P
M
--
T
K
A
R
L
T
N
P
K
F
Q
I
--
A
A
Q
N
A
--
I
T
R
S
G
A
F
T
G
E
V
S
L
Q
I
L
K
D
Y
G
I
S
W
V
V
L
G
H
S
E
R
R
L
Y
Y
G
E
T
N
E
I
V
A
E
K
V
A
Q
A
C
A
A
G
F
H
V
I
V
C
V
G
E
T
N
E
E
R
E
A
G
R
T
A
A
V
V
L
T
Q
L
A
A
V
A
Q
K
L
S
K
E
A
W
-
S
R
V
V
I
A
Y
E
P
V
W
A
I
G
T
G
K
V
A
T
P
Q
Q
A
Q
E
V
H
E
L
L
R
---
R
W
V
---
R
--
S
--
K
L
--
G
--
T
D
I
A
A
Q
L
R
I
L
Y
G
G
S
V
T
A
K
N
A
R
T
L
Y
Q
M
R
D
I
N
G
F
L
V
G
G
A
S
L
K
-
P
E
F
V
E
I
I
E
A
-----
46
PsiBlast_CBE
84.63
43%
-122
- C7 -
-
4G1K
4
?
B:
[30-270]
---------
V
I
G
N
W
K
M
H
G
-
R
L
S
G
N
Q
A
L
--
L
T
--
E
--
V
A
Q
G
A
Q
A
V
H
D
N
--
V
A
I
G
V
C
V
---
P
F
P
Y
L
--
A
Q
--
A
Q
A
Q
L
Q
G
G
--
R
V
S
W
G
S
Q
D
V
S
-
A
H
E
Q
G
A
Y
T
G
E
V
A
A
G
M
V
A
E
F
G
A
A
Y
A
I
V
G
H
S
E
R
R
A
Y
H
G
E
S
N
E
T
V
A
A
K
A
R
R
A
L
A
A
G
L
T
P
I
V
C
V
G
E
T
L
A
E
R
E
A
G
T
T
E
Q
V
V
G
A
Q
L
D
A
V
L
A
V
L
S
P
D
E
-
A
A
R
I
V
V
A
Y
E
P
V
W
A
I
G
T
G
K
S
A
T
A
E
Q
A
Q
Q
V
H
A
F
L
R
---
G
R
L
-
A
----
A
--
K
G
--
A
--
G
H
V
S
----
L
L
Y
G
G
S
V
K
A
D
N
A
A
E
L
F
G
Q
P
D
I
D
G
G
L
I
G
G
A
S
L
K
S
G
D
F
L
A
I
C
R
A
-----
43
PsiBlast_CBE
84.53
41%
-103
- C7 -
-
1CI1
2
TPIS_TRYCR
A:
[7-249]
-------
P
I
A
A
A
N
W
K
C
N
G
S
E
S
L
L
V
P
L
I
E
T
L
N
--
A
-------
A
T
F
D
H
D
--
V
Q
C
V
V
A
P
---
T
F
L
H
I
--
P
M
--
T
K
A
R
L
T
N
P
K
F
Q
I
--
A
A
Q
N
A
--
I
T
R
S
G
A
F
T
G
E
V
S
L
Q
I
L
K
D
Y
G
I
S
W
V
V
L
G
H
S
E
R
R
L
Y
Y
G
E
T
N
E
I
V
A
E
K
V
A
Q
A
C
A
A
G
F
H
V
I
V
C
V
G
E
T
N
E
E
R
E
A
G
R
T
A
A
V
V
L
T
Q
L
A
A
V
A
Q
K
L
S
K
E
A
W
-
S
R
V
V
I
A
Y
E
P
V
W
A
I
G
T
G
K
V
A
T
P
Q
Q
A
Q
E
V
H
E
L
L
R
---
R
W
V
---
R
--
S
--
K
L
--
G
--
T
D
I
A
A
Q
L
R
I
L
Y
G
G
S
V
T
A
K
N
A
R
T
L
Y
Q
M
R
D
I
N
G
F
L
V
G
G
A
S
L
K
-
P
E
F
V
E
I
I
E
A
-----
37
PsiBlast_CBE
84.47
42%
-105
- C7 -
-
4HHP
1
?
B:
[7-249]
-------
P
I
A
A
A
N
W
K
C
N
G
S
E
S
L
L
V
P
L
I
E
T
L
N
--
A
-------
A
T
F
D
H
D
--
V
Q
C
V
V
A
P
---
T
F
L
H
I
--
P
M
--
T
K
A
R
L
T
N
P
K
F
Q
I
--
A
A
Q
N
A
--
I
T
R
S
G
A
F
T
G
E
V
S
L
Q
I
L
K
D
Y
G
I
S
W
V
V
L
G
H
S
E
R
R
L
Y
Y
G
D
T
N
E
I
V
A
E
K
V
A
Q
A
C
A
A
G
F
H
V
I
V
C
V
G
E
T
N
E
E
R
E
A
G
R
T
A
A
V
V
L
T
Q
L
A
A
V
A
Q
K
L
S
K
E
A
W
-
S
R
V
V
I
A
Y
E
P
V
W
A
I
G
T
G
K
V
A
T
P
Q
Q
A
Q
E
V
H
E
L
L
R
---
R
W
V
---
R
--
S
--
K
L
--
G
--
T
D
I
A
A
Q
L
R
I
L
Y
G
G
S
V
T
A
K
N
A
R
T
L
Y
Q
M
R
D
I
N
G
F
L
V
G
G
A
S
L
K
-
P
E
F
V
E
I
I
E
A
-----
132
HHSearch
84.44
39%
-99
- C7 -
-
1TRE
-
TPIS_ECOLI
A:
[3-255]
----
M
R
H
P
L
V
M
G
N
W
K
L
N
G
S
R
H
M
V
H
E
L
V
S
N
L
R
--
K
--
E
L
A
----
G
V
A
G
--
C
A
V
A
I
A
P
---
P
E
M
Y
I
--
D
M
--
A
K
R
E
A
E
--
G
S
H
I
M
L
G
A
Q
N
V
N
-
L
N
L
S
G
A
F
T
G
E
T
S
A
A
M
L
K
D
I
G
A
Q
Y
I
I
I
G
H
S
E
R
R
T
Y
H
K
E
S
D
E
L
I
A
K
K
F
A
V
L
K
E
Q
G
L
T
P
V
L
C
I
G
E
T
E
A
E
N
E
A
G
K
T
E
E
V
C
A
R
Q
I
D
A
V
L
K
T
Q
G
A
A
A
F
E
-
G
A
V
I
A
Y
E
P
V
W
A
I
G
T
G
K
S
A
T
P
A
Q
A
Q
A
V
H
K
F
I
R
---
D
H
I
-
A
K
V
--
D
A
-
N
I
--
A
--
E
Q
V
I
----
I
Q
Y
G
G
S
V
N
A
S
N
A
A
E
L
F
A
Q
P
D
I
D
G
A
L
V
G
G
A
S
L
K
A
D
A
F
A
V
I
V
K
A
A
E
A
A
K
32
PsiBlast_CBE
84.14
44%
-81
- C7 -
-
2BTM
1
TPIS_GEOSE
B:
[3-248]
-------
P
I
I
A
G
N
W
K
M
N
G
T
L
A
E
A
V
Q
F
V
E
D
V
K
--
G
--
H
V
P
P
---
A
D
E
V
--
I
S
V
V
C
A
P
---
F
L
F
L
D
--
R
L
--
V
Q
A
----
A
D
G
T
D
L
K
I
G
A
Q
T
M
H
F
A
D
Q
G
A
Y
T
G
E
V
S
P
V
M
L
K
D
L
G
V
T
Y
V
I
L
G
H
S
E
R
R
Q
M
F
A
E
T
D
E
T
V
N
K
K
V
L
A
A
F
T
R
G
L
I
P
I
I
C
C
G
E
S
L
E
E
R
E
A
G
Q
T
N
A
V
V
A
S
Q
V
E
K
A
L
A
G
L
T
P
E
Q
V
K
-
Q
A
V
I
A
Y
E
P
I
W
A
I
G
T
G
K
S
S
T
P
E
D
A
N
S
V
C
G
H
I
R
---
S
V
V
-
S
R
L
FG
P
--
E
A
--
A
--
E
A
I
R
----
I
Q
Y
G
G
S
V
K
P
D
N
I
R
D
F
L
A
Q
Q
Q
I
D
G
A
L
V
G
G
A
S
L
E
P
A
S
F
L
Q
L
V
E
A
-----
59
PsiBlast_CBE
83.30
38%
-91
- C7 -
-
4MVA
2
?
A:
[28-277]
-------
P
L
V
M
G
N
W
K
L
N
G
S
R
H
M
V
H
E
L
V
S
N
L
R
--
K
--
E
L
A
----
G
V
A
G
--
C
A
V
A
I
A
P
---
P
E
M
Y
I
--
D
M
--
A
K
R
E
A
E
G
S
--
H
I
M
L
G
A
Q
N
V
D
-
L
N
L
S
G
A
F
T
G
E
T
S
A
A
M
L
K
D
I
G
A
Q
Y
I
I
I
G
H
S
E
R
R
T
Y
H
K
E
S
D
E
L
I
A
K
K
F
A
V
L
K
E
Q
G
L
T
P
V
L
C
I
G
E
T
E
A
E
N
E
A
G
K
T
E
E
V
C
A
R
Q
I
D
A
V
L
K
T
Q
G
A
A
A
F
E
G
-
A
V
I
A
Y
E
P
V
W
A
I
G
T
G
K
S
A
T
P
A
Q
A
Q
A
V
H
K
F
I
R
---
D
H
I
-
A
K
V
--
D
---------
A
N
I
A
E
Q
V
I
I
Q
Y
G
G
S
V
N
A
S
N
A
A
E
L
F
A
Q
P
D
I
D
G
A
L
V
G
G
A
S
L
K
A
D
A
F
A
V
I
V
K
A
A
E
A
A
K
150
HHSearch
83.25
38%
-105
- C7 -
-
4MVA
2
?
A:
[25-276]
----
M
R
H
P
L
V
M
G
N
W
K
L
N
G
S
R
H
M
V
H
E
L
V
S
N
L
R
--
K
--
E
L
A
----
G
V
A
G
--
C
A
V
A
I
A
P
---
P
E
M
Y
I
--
D
M
--
A
K
R
E
A
E
--
G
S
H
I
M
L
G
A
Q
N
V
D
-
L
N
L
S
G
A
F
T
G
E
T
S
A
A
M
L
K
D
I
G
A
Q
Y
I
I
I
G
H
S
E
R
R
T
Y
H
K
E
S
D
E
L
I
A
K
K
F
A
V
L
K
E
Q
G
L
T
P
V
L
C
I
G
E
T
E
A
E
N
E
A
G
K
T
E
E
V
C
A
R
Q
I
D
A
V
L
K
T
Q
G
A
A
A
F
E
-
G
A
V
I
A
Y
E
P
V
W
A
I
G
T
G
K
S
A
T
P
A
Q
A
Q
A
V
H
K
F
I
R
---
D
H
I
-
A
K
V
--
D
A
-
N
I
--
A
--
E
Q
V
I
----
I
Q
Y
G
G
S
V
N
A
S
N
A
A
E
L
F
A
Q
P
D
I
D
G
A
L
V
G
G
A
S
L
K
A
D
A
F
A
V
I
V
K
A
A
E
A
A
-
95
PsiBlast_CBE
83.23
39%
-77
- C7 -
-
1LZO
1
TPIS_PLAFA
D:
[6-246]
--------
F
V
A
A
N
W
K
C
N
G
T
L
E
S
I
K
S
L
T
N
S
F
N
--
N
--
L
----
D
F
D
P
S
K
--
L
D
V
V
V
F
P
---
V
S
V
H
Y
--
D
H
--
T
R
K
L
L
Q
S
K
F
S
T
G
---
I
Q
N
V
S
K
F
-
G
N
G
S
Y
T
G
E
V
S
A
E
I
A
K
D
L
N
I
E
Y
V
I
I
G
H
F
E
R
R
K
Y
F
H
E
T
D
E
D
V
R
E
K
L
Q
A
S
L
K
N
N
L
K
A
V
V
C
F
G
E
S
L
E
Q
R
E
Q
N
K
T
I
E
V
I
T
K
Q
V
K
A
F
V
D
L
I
--
D
N
F
D
N
-
V
I
L
V
Y
E
P
L
W
A
I
G
T
G
K
T
A
T
P
E
Q
A
Q
L
V
H
K
E
I
R
KIV
K
D
T
-
C
G
E
--
K
--
Q
A
-----
N
Q
I
R
----
I
L
Y
G
G
S
V
N
T
E
N
C
S
S
L
I
Q
Q
E
D
I
D
G
F
L
V
G
N
A
S
L
-
K
E
S
F
V
D
I
I
K
S
-----
127
PsiBlast_CBE
83.18
39%
-74
- C7 -
-
5BMX
3
TPIS_PLAFA
B:
[6-246]
--------
F
V
A
A
N
W
K
C
N
G
T
L
E
S
I
K
S
L
T
N
S
F
N
--
N
--
L
----
D
F
D
P
S
K
--
L
D
V
V
V
F
P
---
V
S
V
H
Y
--
D
H
--
T
R
K
L
L
Q
S
K
F
S
T
G
---
I
Q
N
V
S
K
F
-
G
N
G
S
Y
N
G
E
V
S
A
E
I
A
K
D
L
N
I
E
Y
V
I
I
G
H
F
E
R
R
K
Y
F
H
E
T
D
E
D
V
R
E
K
L
Q
A
S
L
K
N
N
L
K
A
V
V
C
F
G
E
S
L
E
Q
R
E
Q
N
K
T
I
E
V
I
T
K
Q
V
K
A
F
V
D
L
I
--
D
N
F
D
N
-
V
I
L
V
Y
E
P
L
W
A
I
G
T
G
K
T
A
T
P
E
Q
A
Q
L
V
H
K
E
I
R
K
I
V
K
D
T
-
C
G
E
--
K
--
Q
A
-----
N
Q
I
R
----
I
L
Y
G
G
S
V
N
T
E
N
C
S
S
L
I
Q
Q
E
D
I
D
G
F
L
V
G
N
A
S
L
-
K
E
S
F
V
D
I
I
K
S
-----
117
PsiBlast_CBE
82.96
39%
-78
- C7 -
-
2VFH
1
TPIS_PLAFA
B:
[6-246]
--------
F
V
A
A
N
W
K
C
N
G
T
L
E
S
I
K
S
L
T
N
S
F
N
--
N
--
L
----
D
F
D
P
S
K
--
L
D
V
V
V
F
P
---
V
S
V
H
Y
--
D
H
--
T
R
K
L
L
Q
S
K
F
S
T
G
---
I
Q
N
V
S
K
F
-
G
N
G
S
Y
T
G
E
V
S
A
E
I
A
K
D
L
N
I
E
Y
V
I
I
G
H
W
E
R
R
K
Y
F
H
E
T
D
E
D
V
R
E
K
L
Q
A
S
L
K
N
N
L
K
A
V
V
C
F
G
E
S
L
E
Q
R
E
Q
N
K
T
I
E
V
I
T
K
Q
V
K
A
F
V
D
L
I
--
D
N
F
D
N
-
V
I
L
V
Y
E
P
L
W
A
I
G
T
G
K
T
A
T
P
E
Q
A
Q
L
V
H
K
E
I
R
KIV
K
D
T
-
C
G
E
--
K
--
Q
A
-----
N
Q
I
R
----
I
L
Y
G
G
S
V
N
T
E
N
C
S
S
L
I
Q
Q
E
D
I
D
G
F
L
V
G
N
A
S
L
-
K
E
S
F
V
D
I
I
K
S
-----
144
HHSearch
82.91
41%
-89
- C7 -
-
4Z0J
10
TPIS_PLAFA
B:
[2-247]
----
A
R
K
Y
F
V
A
A
N
W
K
C
N
G
T
L
E
S
I
K
S
L
T
N
S
F
N
--
N
--
L
D
F
----
D
P
S
K
--
L
D
V
V
V
F
P
---
V
S
V
H
Y
--
D
H
--
T
R
K
L
L
Q
---
S
K
F
S
T
G
I
Q
N
V
S
-
K
F
G
N
G
A
Y
T
G
E
V
S
A
E
I
A
K
D
L
N
I
E
Y
V
I
I
G
H
S
E
R
R
K
Y
F
H
E
T
D
E
D
V
R
E
K
L
Q
A
S
L
K
N
N
L
K
A
V
V
C
F
G
E
S
L
E
Q
R
E
Q
N
K
T
I
E
V
I
T
K
Q
V
K
A
F
V
D
L
I
--
D
N
F
D
-
N
V
I
L
V
Y
E
P
L
W
A
I
G
T
G
K
T
A
T
P
E
Q
A
Q
L
V
H
K
E
I
R
---
K
I
V
-
K
D
T
--
C
G
E
K
Q
--
A
--
N
Q
I
R
----
I
L
Y
G
G
S
------
S
S
L
I
Q
Q
E
D
I
D
G
F
L
V
G
N
A
S
L
K
E
-
S
F
V
D
I
I
K
S
A
----
130
PsiBlast_CBE
82.91
39%
-75
- C7 -
-
5BMW
8
TPIS_PLAFA
A:
[6-246]
--------
F
V
A
A
N
W
K
C
N
G
T
L
E
S
I
K
S
L
T
N
S
F
N
--
N
--
L
----
D
F
D
P
S
K
--
L
D
V
V
V
F
P
---
V
S
V
H
Y
--
D
H
--
T
R
K
L
L
Q
S
K
F
S
T
G
---
I
Q
N
V
S
K
F
-
G
N
G
S
Y
V
G
E
V
S
A
E
I
A
K
D
L
N
I
E
Y
V
I
I
G
H
F
E
R
R
K
Y
F
H
E
T
D
E
D
V
R
E
K
L
Q
A
S
L
K
N
N
L
K
A
V
V
C
F
G
E
S
L
E
Q
R
E
Q
N
K
T
I
E
V
I
T
K
Q
V
K
A
F
V
D
L
I
--
D
N
F
D
N
-
V
I
L
V
Y
E
P
L
W
A
I
G
T
G
K
T
A
T
P
E
Q
A
Q
L
V
H
K
E
I
R
K
I
V
K
D
T
-
C
G
E
--
K
--
Q
A
-----
N
Q
I
R
----
I
L
Y
G
G
S
V
N
T
E
N
C
S
S
L
I
Q
Q
E
D
I
D
G
F
L
V
G
N
A
S
L
-
K
E
S
F
V
D
I
I
K
S
-----
115
PsiBlast_CBE
82.41
39%
-76
- C7 -
-
4ZZ9
2
TPIS_PLAFA
B:
[6-246]
--------
F
V
A
A
N
W
K
C
N
G
T
L
E
S
I
K
S
L
T
N
S
F
N
--
N
--
L
----
D
F
D
P
S
K
--
L
D
V
V
V
F
P
---
V
S
V
H
Y
--
D
H
--
T
R
K
L
L
Q
S
K
F
S
T
G
---
I
Q
N
V
S
K
F
-
G
N
G
S
Y
S
G
E
V
S
A
E
I
A
K
D
L
N
I
E
Y
V
I
I
G
H
F
E
R
R
K
Y
F
H
E
T
D
E
D
V
R
E
K
L
Q
A
S
L
K
N
N
L
K
A
V
V
C
F
G
E
S
L
E
Q
R
E
Q
N
K
T
I
E
V
I
T
K
Q
V
K
A
F
V
D
L
I
--
D
N
F
D
N
-
V
I
L
V
Y
E
P
L
W
A
I
G
T
G
K
T
A
T
P
E
Q
A
Q
L
V
H
K
E
I
R
K
I
V
K
D
T
-
C
G
E
--
K
--
Q
A
-----
N
Q
I
R
----
I
L
Y
G
G
S
V
N
T
E
N
C
S
S
L
I
Q
Q
E
D
I
D
G
F
L
V
G
N
A
S
L
-
K
E
S
F
V
D
I
I
K
S
-----
58
PsiBlast_CBE
82.02
38%
-94
- C7 -
-
4MVA
2
?
B:
[28-277]
-------
P
L
V
M
G
N
W
K
L
N
G
S
R
H
M
V
H
E
L
V
S
N
L
R
--
K
--
E
L
A
----
G
V
A
G
--
C
A
V
A
I
A
P
---
P
E
M
Y
I
--
D
M
--
A
K
R
E
A
E
G
S
--
H
I
M
L
G
A
Q
N
V
D
-
L
N
L
S
G
A
F
T
G
E
T
S
A
A
M
L
K
D
I
G
A
Q
Y
I
I
I
G
H
S
E
R
R
T
Y
H
K
E
S
D
E
L
I
A
K
K
F
A
V
L
K
E
Q
G
L
T
P
V
L
C
I
G
E
T
E
A
E
N
E
A
G
K
T
E
E
V
C
A
R
Q
I
D
A
V
L
K
T
Q
G
A
A
A
F
E
G
-
A
V
I
A
Y
E
P
V
W
A
I
G
T
G
K
S
A
T
P
A
Q
A
Q
A
V
H
K
F
I
R
---
D
H
I
-
A
K
V
--
D
---------
A
N
I
A
EQVI
I
Q
Y
G
G
S
V
N
A
S
N
A
A
E
L
F
A
Q
P
D
I
D
G
A
L
V
G
G
A
S
L
K
A
D
A
F
A
V
I
V
K
A
A
E
A
A
K
122
PsiBlast_CBE
81.98
39%
-74
- C7 -
-
3PSW
1
TPIS_PLAFA
A:
[6-246]
--------
F
V
A
A
N
W
K
C
N
G
T
L
E
S
I
K
S
L
T
N
S
F
N
--
N
--
L
----
D
F
D
P
S
K
--
L
D
V
V
V
F
P
---
V
S
V
H
Y
--
D
H
--
T
R
K
L
L
Q
S
K
F
S
T
G
---
I
Q
N
V
S
K
F
-
G
N
G
S
Y
T
G
E
V
S
A
E
I
A
K
D
L
N
I
E
Y
V
I
I
G
H
F
Q
R
R
K
Y
F
H
E
T
D
E
D
V
R
E
K
L
Q
A
S
L
K
N
N
L
K
A
V
V
C
F
G
E
S
L
E
Q
R
E
Q
N
K
T
I
E
V
I
T
K
Q
V
K
A
F
V
D
L
I
--
D
N
F
D
N
-
V
I
L
V
Y
E
P
L
W
A
I
G
T
G
K
T
A
T
P
E
Q
A
Q
L
V
H
K
E
I
R
K
I
V
K
D
T
-
C
G
E
--
K
--
Q
A
-----
N
Q
I
R
----
I
L
Y
G
G
S
V
N
T
E
N
C
S
S
L
I
Q
Q
E
D
I
D
G
F
L
V
G
N
A
S
L
-
K
E
S
F
V
D
I
I
K
S
-----
79
PsiBlast_CBE
81.95
39%
-79
- C7 -
-
4Z0S
4
TPIS_PLAFA
A:
[6-246]
--------
F
V
A
A
N
W
K
C
N
G
T
L
E
S
I
K
S
L
T
N
S
F
N
--
N
--
L
----
D
F
D
P
S
K
--
L
D
V
V
V
F
P
---
V
S
V
H
Y
--
D
H
--
T
R
K
L
L
Q
S
K
---
F
S
T
G
I
Q
N
V
S
K
F
-
G
N
G
S
Y
T
G
E
V
S
A
E
I
A
K
D
L
N
I
E
Y
V
I
I
G
H
A
E
R
R
K
Y
F
H
E
T
D
E
D
V
R
E
K
L
Q
A
S
L
K
N
N
L
K
A
V
V
C
F
G
E
S
L
E
Q
R
E
Q
N
K
T
I
E
V
I
T
K
Q
V
K
A
F
V
D
L
I
--
D
N
F
D
N
-
V
I
L
V
Y
E
P
L
W
A
I
G
T
G
K
T
A
T
P
E
Q
A
Q
L
V
H
K
E
I
R
K
I
V
K
D
T
-
C
G
E
--
K
--
Q
A
-----
N
Q
I
R
----
I
L
Y
G
G
S
V
N
T
E
N
C
S
S
L
I
Q
Q
E
D
I
D
G
F
L
V
G
N
A
S
L
-
K
E
S
F
V
D
I
I
K
S
-----
129
PsiBlast_CBE
81.91
39%
-75
* C7 *
-
5BMW
2
TPIS_PLAFA
B:
[6-246]
--------
F
V
A
A
N
W
K
C
N
G
T
L
E
S
I
K
S
L
T
N
S
F
N
--
N
--
L
----
D
F
D
P
S
K
--
L
D
V
V
V
F
P
---
V
S
V
H
Y
--
D
H
--
T
R
K
L
L
Q
S
K
F
S
T
G
---
I
Q
N
V
S
K
F
-
G
N
G
S
Y
V
G
E
V
S
A
E
I
A
K
D
L
N
I
E
Y
V
I
I
G
H
F
E
R
R
K
Y
F
H
E
T
D
E
D
V
R
E
K
L
Q
A
S
L
K
N
N
L
K
A
V
V
C
F
G
E
S
L
E
Q
R
E
Q
N
K
T
I
E
V
I
T
K
Q
V
K
A
F
V
D
L
I
--
D
N
F
D
N
-
V
I
L
V
Y
E
P
L
W
A
I
G
T
G
K
T
A
T
P
E
Q
A
Q
L
V
H
K
E
I
R
K
I
V
K
D
T
-
C
G
E
--
K
--
Q
A
-----
N
Q
I
R
----
I
L
Y
G
G
S
V
N
T
E
N
C
S
S
L
I
Q
Q
E
D
I
D
G
F
L
V
G
N
A
S
L
-
K
E
S
F
V
D
I
I
K
S
-----
35
PsiBlast_CBE
81.79
43%
-80
- C7 -
-
1BTM
1
TPIS_GEOSE
B:
[3-248]
-------
P
I
I
A
G
N
W
K
M
H
K
T
L
A
E
A
V
Q
F
V
E
D
V
K
--
G
--
H
V
P
P
---
A
D
E
V
--
I
S
V
V
C
A
P
---
F
L
F
L
D
--
R
L
--
V
Q
A
----
A
D
G
T
D
L
K
I
G
A
Q
T
M
H
F
A
D
Q
G
A
Y
T
G
E
V
S
P
V
M
L
K
D
L
G
V
T
Y
V
I
L
G
H
S
E
R
R
Q
M
F
A
E
T
D
E
T
V
N
K
K
V
L
A
A
F
T
R
G
L
I
P
I
I
C
C
G
E
S
L
E
E
R
E
A
G
Q
T
N
A
V
V
A
S
Q
V
E
K
A
L
A
G
L
T
P
E
Q
V
K
-
Q
A
V
I
A
Y
E
P
I
W
A
I
G
T
G
K
S
S
T
P
E
D
A
N
S
V
C
G
H
I
R
---
S
V
V
-
S
R
L
FG
P
--
E
A
--
A
--
E
A
I
R
----
I
Q
Y
G
G
S
V
K
P
D
N
I
R
D
F
L
A
Q
Q
Q
I
D
G
P
L
V
G
G
A
S
L
E
P
A
S
F
L
Q
L
V
E
A
-----
92
PsiBlast_CBE
81.75
39%
-76
- C7 -
-
1M7P
1
TPIS_PLAFA
A:
[6-246]
--------
F
V
A
A
N
W
K
C
N
G
T
L
E
S
I
K
S
L
T
N
S
F
N
--
N
--
L
----
D
F
D
P
S
K
--
L
D
V
V
V
F
P
---
V
S
V
H
Y
--
D
H
--
T
R
K
L
L
Q
S
K
F
S
T
G
---
I
Q
N
V
S
K
F
-
G
N
G
S
Y
T
G
E
V
S
A
E
I
A
K
D
L
N
I
E
Y
V
I
I
G
H
F
E
R
R
K
Y
F
H
E
T
D
E
D
V
R
E
K
L
Q
A
S
L
K
N
N
L
K
A
V
V
C
F
G
E
S
L
E
Q
R
E
Q
N
K
T
I
E
V
I
T
K
Q
V
K
A
F
V
D
L
I
--
D
N
F
D
N
-
V
I
L
V
Y
E
P
L
W
A
I
G
T
G
K
T
A
T
P
E
Q
A
Q
L
V
H
K
E
I
R
K
I
V
K
D
T
-
C
G
E
--
K
--
Q
A
-----
N
Q
I
R
----
I
L
Y
G
G
S
V
N
T
E
N
C
S
S
L
I
Q
Q
E
D
I
D
G
F
L
V
G
N
A
S
L
-
K
E
S
F
V
D
I
I
K
S
-----
126
PsiBlast_CBE
81.68
39%
-76
- C7 -
-
5BMX
3
TPIS_PLAFA
C:
[6-246]
--------
F
V
A
A
N
W
K
C
N
G
T
L
E
S
I
K
S
L
T
N
S
F
N
--
N
--
L
----
D
F
D
P
S
K
--
L
D
V
V
V
F
P
---
V
S
V
H
Y
--
D
H
--
T
R
K
L
L
Q
S
K
F
S
T
G
---
I
Q
N
V
S
K
F
-
G
N
G
S
Y
N
G
E
V
S
A
E
I
A
K
D
L
N
I
E
Y
V
I
I
G
H
F
E
R
R
K
Y
F
H
E
T
D
E
D
V
R
E
K
L
Q
A
S
L
K
N
N
L
K
A
V
V
C
F
G
E
S
L
E
Q
R
E
Q
N
K
T
I
E
V
I
T
K
Q
V
K
A
F
V
D
L
I
--
D
N
F
D
N
-
V
I
L
V
Y
E
P
L
W
A
I
G
T
G
K
T
A
T
P
E
Q
A
Q
L
V
H
K
E
I
R
K
I
V
K
D
T
-
C
G
E
--
K
--
Q
A
-----
N
Q
I
R
----
I
L
Y
G
G
S
V
N
T
E
N
C
S
S
L
I
Q
Q
E
D
I
D
G
F
L
V
G
N
A
S
L
-
K
E
S
F
V
D
I
I
K
S
-----
128
PsiBlast_CBE
81.66
39%
-74
- C7 -
-
5BMX
3
TPIS_PLAFA
A:
[6-246]
--------
F
V
A
A
N
W
K
C
N
G
T
L
E
S
I
K
S
L
T
N
S
F
N
--
N
--
L
----
D
F
D
P
S
K
--
L
D
V
V
V
F
P
---
V
S
V
H
Y
--
D
H
--
T
R
K
L
L
Q
S
K
F
S
T
G
---
I
Q
N
V
S
K
F
-
G
N
G
S
Y
N
G
E
V
S
A
E
I
A
K
D
L
N
I
E
Y
V
I
I
G
H
F
E
R
R
K
Y
F
H
E
T
D
E
D
V
R
E
K
L
Q
A
S
L
K
N
N
L
K
A
V
V
C
F
G
E
S
L
E
Q
R
E
Q
N
K
T
I
E
V
I
T
K
Q
V
K
A
F
V
D
L
I
--
D
N
F
D
N
-
V
I
L
V
Y
E
P
L
W
A
I
G
T
G
K
T
A
T
P
E
Q
A
Q
L
V
H
K
E
I
R
K
I
V
K
D
T
-
C
G
E
--
K
--
Q
A
-----
N
Q
I
R
----
I
L
Y
G
G
S
V
N
T
E
N
C
S
S
L
I
Q
Q
E
D
I
D
G
F
L
V
G
N
A
S
L
-
K
E
S
F
V
D
I
I
K
S
-----
112
PsiBlast_CBE
81.59
39%
-81
- C7 -
-
3PSV
1
TPIS_PLAFA
A:
[6-246]
--------
F
V
A
A
N
W
K
C
N
G
T
L
E
S
I
K
S
L
T
N
S
F
N
--
N
--
L
----
D
F
D
P
S
K
--
L
D
V
V
V
F
P
---
V
S
V
H
Y
--
D
H
--
T
R
K
L
L
Q
S
K
F
S
T
G
---
I
Q
N
V
S
K
F
-
G
N
G
S
Y
T
G
E
V
S
A
E
I
A
K
D
L
N
I
E
Y
V
I
I
G
H
F
D
R
R
K
Y
F
H
E
T
D
E
D
V
R
E
K
L
Q
A
S
L
K
N
N
L
K
A
V
V
C
F
G
E
S
L
E
Q
R
E
Q
N
K
T
I
E
V
I
T
K
Q
V
K
A
F
V
D
L
I
--
D
N
F
D
N
-
V
I
L
V
Y
E
P
L
W
A
I
G
T
---
A
T
P
E
Q
A
Q
L
V
H
K
E
I
R
K
I
V
K
D
T
-
C
G
E
--
K
--
Q
A
-----
N
Q
I
R
----
I
L
Y
G
G
S
V
N
T
E
N
C
S
S
L
I
Q
Q
E
D
I
D
G
F
L
V
G
N
A
S
L
-
K
E
S
F
V
D
I
I
K
S
-----
87
PsiBlast_CBE
81.44
39%
-72
- C7 -
-
2VFI
3
TPIS_PLAFA
B:
[6-246]
--------
F
V
A
A
N
W
K
C
N
G
T
L
E
S
I
K
S
L
T
N
S
F
N
--
N
--
L
----
D
F
D
P
S
K
--
L
D
V
V
V
F
P
---
V
S
V
H
Y
--
D
H
--
T
R
K
L
L
Q
S
K
F
S
T
G
---
I
Q
N
V
S
K
F
-
G
N
G
S
Y
T
G
E
V
S
A
E
I
A
K
D
L
N
I
E
Y
V
I
I
G
H
F
E
R
R
K
Y
F
H
E
T
D
E
D
V
R
E
K
L
Q
A
S
L
K
N
N
L
K
A
V
V
C
F
G
E
S
L
E
Q
R
E
Q
N
K
T
I
E
V
I
T
K
Q
V
K
A
F
V
D
L
I
--
D
N
F
D
N
-
V
I
L
V
Y
E
P
L
W
A
I
G
T
G
K
T
A
T
P
E
Q
A
Q
L
V
H
K
E
I
R
KIV
K
D
T
-
C
G
E
--
K
--
Q
A
-----
N
Q
I
R
----
I
L
Y
G
G
S
V
N
T
E
N
C
S
S
L
I
Q
Q
E
D
I
D
G
F
L
V
G
N
A
S
L
-
K
E
S
F
V
D
I
I
K
S
-----
70
PsiBlast_CBE
81.43
40%
-73
- C7 -
-
2VFE
3
TPIS_PLAFA
A:
[6-246]
--------
F
V
A
A
N
W
K
C
N
G
T
L
E
S
I
K
S
L
T
N
S
F
N
--
N
--
L
----
D
F
D
P
S
K
--
L
D
V
V
V
F
P
---
V
S
V
H
Y
--
D
H
--
T
R
K
L
L
Q
S
K
F
S
T
G
---
I
Q
N
V
S
K
F
-
G
N
G
S
Y
T
G
E
V
S
A
E
I
A
K
D
L
N
I
E
Y
V
I
I
G
H
S
E
R
R
K
Y
F
H
E
T
D
E
D
V
R
E
K
L
Q
A
S
L
K
N
N
L
K
A
V
V
C
F
G
E
S
L
E
Q
R
E
Q
N
K
T
I
E
V
I
T
K
Q
V
K
A
F
V
D
L
I
--
D
N
F
D
N
-
V
I
L
V
Y
E
P
L
W
A
I
G
T
G
K
T
A
T
P
E
Q
A
Q
L
V
H
K
E
I
R
K
I
V
K
D
T
-
C
G
E
--
K
--
Q
A
-----
N
Q
I
R
----
I
L
Y
G
G
S
V
N
T
E
N
C
S
S
L
I
Q
Q
E
D
I
D
G
F
L
V
G
N
A
S
L
-
K
E
S
F
V
D
I
I
K
S
-----
118
PsiBlast_CBE
81.32
39%
-71
- C7 -
-
2VFH
1
TPIS_PLAFA
A:
[6-246]
--------
F
V
A
A
N
W
K
C
N
G
T
L
E
S
I
K
S
L
T
N
S
F
N
--
N
--
L
----
D
F
D
P
S
K
--
L
D
V
V
V
F
P
---
V
S
V
H
Y
--
D
H
--
T
R
K
L
L
Q
S
K
F
S
T
G
---
I
Q
N
V
S
K
F
-
G
N
G
S
Y
T
G
E
V
S
A
E
I
A
K
D
L
N
I
E
Y
V
I
I
G
H
W
E
R
R
K
Y
F
H
E
T
D
E
D
V
R
E
K
L
Q
A
S
L
K
N
N
L
K
A
V
V
C
F
G
E
S
L
E
Q
R
E
Q
N
K
T
I
E
V
I
T
K
Q
V
K
A
F
V
D
L
I
--
D
N
F
D
N
-
V
I
L
V
Y
E
P
L
W
A
I
G
T
G
K
T
A
T
P
E
Q
A
Q
L
V
H
K
E
I
R
K
I
V
K
D
T
-
C
G
E
--
K
--
Q
A
-----
N
Q
I
R
----
I
L
Y
G
G
S
V
N
T
E
N
C
S
S
L
I
Q
Q
E
D
I
D
G
F
L
V
G
N
A
S
L
-
K
E
S
F
V
D
I
I
K
S
-----
90
PsiBlast_CBE
81.29
39%
-73
- C7 -
-
1O5X
1
TPIS_PLAFA
A:
[6-246]
--------
F
V
A
A
N
W
K
C
N
G
T
L
E
S
I
K
S
L
T
N
S
F
N
--
N
--
L
----
D
F
D
P
S
K
--
L
D
V
V
V
F
P
---
V
S
V
H
Y
--
D
H
--
T
R
K
L
L
Q
S
K
F
S
T
G
---
I
Q
N
V
S
K
F
-
G
N
G
S
Y
T
G
E
V
S
A
E
I
A
K
D
L
N
I
E
Y
V
I
I
G
H
F
E
R
R
K
Y
F
H
E
T
D
E
D
V
R
E
K
L
Q
A
S
L
K
N
N
L
K
A
V
V
C
F
G
E
S
L
E
Q
R
E
Q
N
K
T
I
E
V
I
T
K
Q
V
K
A
F
V
D
L
I
--
D
N
F
D
N
-
V
I
L
V
Y
E
P
L
W
A
I
G
T
G
K
T
A
T
P
E
Q
A
Q
L
V
H
K
E
I
R
K
I
V
K
D
T
-
C
G
E
--
K
--
Q
A
-----
N
Q
I
R
----
I
L
Y
G
G
S
V
N
T
E
N
C
S
S
L
I
Q
Q
E
D
I
D
G
F
L
V
G
N
A
S
L
-
K
E
S
F
V
D
I
I
K
S
-----
97
PsiBlast_CBE
81.25
39%
-71
- C7 -
-
1LYX
1
TPIS_PLAFA
A:
[6-246]
--------
F
V
A
A
N
W
K
C
N
G
T
L
E
S
I
K
S
L
T
N
S
F
N
--
N
--
L
----
D
F
D
P
S
K
--
L
D
V
V
V
F
P
---
V
S
V
H
Y
--
D
H
--
T
R
K
L
L
Q
S
K
F
S
T
G
---
I
Q
N
V
S
K
F
-
G
N
G
S
Y
T
G
E
V
S
A
E
I
A
K
D
L
N
I
E
Y
V
I
I
G
H
F
E
R
R
K
Y
F
H
E
T
D
E
D
V
R
E
K
L
Q
A
S
L
K
N
N
L
K
A
V
V
C
F
G
E
S
L
E
Q
R
E
Q
N
K
T
I
E
V
I
T
K
Q
V
K
A
F
V
D
L
I
--
D
N
F
D
N
-
V
I
L
V
Y
E
P
L
W
A
I
G
T
G
K
T
A
T
P
E
Q
A
Q
L
V
H
K
E
I
R
K
I
V
K
D
T
-
C
G
E
--
K
--
Q
A
-----
N
Q
I
R
----
I
L
Y
G
G
S
V
N
T
E
N
C
S
S
L
I
Q
Q
E
D
I
D
G
F
L
V
G
N
A
S
L
-
K
E
S
F
V
D
I
I
K
S
-----
91
PsiBlast_CBE
81.23
39%
-76
- C7 -
-
1M7P
1
TPIS_PLAFA
B:
[6-246]
--------
F
V
A
A
N
W
K
C
N
G
T
L
E
S
I
K
S
L
T
N
S
F
N
--
N
--
L
----
D
F
D
P
S
K
--
L
D
V
V
V
F
P
---
V
S
V
H
Y
--
D
H
--
T
R
K
L
L
Q
S
K
F
S
T
G
---
I
Q
N
V
S
K
F
-
G
N
G
S
Y
T
G
E
V
S
A
E
I
A
K
D
L
N
I
E
Y
V
I
I
G
H
F
E
R
R
K
Y
F
H
E
T
D
E
D
V
R
E
K
L
Q
A
S
L
K
N
N
L
K
A
V
V
C
F
G
E
S
L
E
Q
R
E
Q
N
K
T
I
E
V
I
T
K
Q
V
K
A
F
V
D
L
I
--
D
N
F
D
N
-
V
I
L
V
Y
E
P
L
W
A
I
G
T
G
K
T
A
T
P
E
Q
A
Q
L
V
H
K
E
I
R
KIV
K
D
T
-
C
G
E
--
K
--
Q
A
-----
N
Q
I
R
----
I
L
Y
G
G
S
V
N
T
E
N
C
S
S
L
I
Q
Q
E
D
I
D
G
F
L
V
G
N
A
S
L
-
K
E
S
F
V
D
I
I
K
S
-----
94
PsiBlast_CBE
81.19
39%
-73
- C7 -
-
1M7O
1
TPIS_PLAFA
A:
[6-246]
--------
F
V
A
A
N
W
K
C
N
G
T
L
E
S
I
K
S
L
T
N
S
F
N
--
N
--
L
----
D
F
D
P
S
K
--
L
D
V
V
V
F
P
---
V
S
V
H
Y
--
D
H
--
T
R
K
L
L
Q
S
K
F
S
T
G
---
I
Q
N
V
S
K
F
-
G
N
G
S
Y
T
G
E
V
S
A
E
I
A
K
D
L
N
I
E
Y
V
I
I
G
H
F
E
R
R
K
Y
F
H
E
T
D
E
D
V
R
E
K
L
Q
A
S
L
K
N
N
L
K
A
V
V
C
F
G
E
S
L
E
Q
R
E
Q
N
K
T
I
E
V
I
T
K
Q
V
K
A
F
V
D
L
I
--
D
N
F
D
N
-
V
I
L
V
Y
E
P
L
W
A
I
G
T
G
K
T
A
T
P
E
Q
A
Q
L
V
H
K
E
I
R
K
I
V
K
D
T
-
C
G
E
--
K
--
Q
A
-----
N
Q
I
R
----
I
L
Y
G
G
S
V
N
T
E
N
C
S
S
L
I
Q
Q
E
D
I
D
G
F
L
V
G
N
A
S
L
-
K
E
S
F
V
D
I
I
K
S
-----
93
PsiBlast_CBE
81.18
39%
-74
- C7 -
-
1M7O
1
TPIS_PLAFA
B:
[6-246]
--------
F
V
A
A
N
W
K
C
N
G
T
L
E
S
I
K
S
L
T
N
S
F
N
--
N
--
L
----
D
F
D
P
S
K
--
L
D
V
V
V
F
P
---
V
S
V
H
Y
--
D
H
--
T
R
K
L
L
Q
S
K
F
S
T
G
---
I
Q
N
V
S
K
F
-
G
N
G
S
Y
T
G
E
V
S
A
E
I
A
K
D
L
N
I
E
Y
V
I
I
G
H
F
E
R
R
K
Y
F
H
E
T
D
E
D
V
R
E
K
L
Q
A
S
L
K
N
N
L
K
A
V
V
C
F
G
E
S
L
E
Q
R
E
Q
N
K
T
I
E
V
I
T
K
Q
V
K
A
F
V
D
L
I
--
D
N
F
D
N
-
V
I
L
V
Y
E
P
L
W
A
I
G
T
G
K
T
A
T
P
E
Q
A
Q
L
V
H
K
E
I
R
KIV
K
D
T
-
C
G
E
--
K
--
Q
A
-----
N
Q
I
R
----
I
L
Y
G
G
S
V
N
T
E
N
C
S
S
L
I
Q
Q
E
D
I
D
G
F
L
V
G
N
A
S
L
-
K
E
S
F
V
D
I
I
K
S
-----
69
PsiBlast_CBE
80.87
40%
-86
- C7 -
-
2VFE
3
TPIS_PLAFA
B:
[6-246]
--------
F
V
A
A
N
W
K
C
N
G
T
L
E
S
I
K
S
L
T
N
S
F
N
--
N
--
L
----
D
F
D
P
S
K
--
L
D
V
V
V
F
P
---
V
S
V
H
Y
--
D
H
--
T
R
K
L
L
Q
S
K
F
S
T
G
---
I
Q
N
V
S
K
F
-
G
N
G
S
Y
T
G
E
V
S
A
E
I
A
K
D
L
N
I
E
Y
V
I
I
G
H
S
E
R
R
K
Y
F
H
E
T
D
E
D
V
R
E
K
L
Q
A
S
L
K
N
N
L
K
A
V
V
C
F
G
E
S
L
E
Q
R
E
Q
N
K
T
I
E
V
I
T
K
Q
V
K
A
F
V
D
L
I
--
D
N
F
D
N
-
V
I
L
V
Y
E
P
L
W
A
I
G
T
G
K
T
A
T
P
E
Q
A
Q
L
V
H
K
E
I
R
K
I
V
K
D
T
-
C
G
E
--
K
--
Q
A
-----
N
Q
I
R
----
I
L
Y
G
G
S
------
S
S
L
I
Q
Q
E
D
I
D
G
F
L
V
G
N
A
S
L
-
K
E
S
F
V
D
I
I
K
S
-----
96
PsiBlast_CBE
80.74
39%
-78
- C7 -
-
1LZO
1
TPIS_PLAFA
B:
[6-246]
--------
F
V
A
A
N
W
K
C
N
G
T
L
E
S
I
K
S
L
T
N
S
F
N
--
N
--
L
----
D
F
D
P
S
K
--
L
D
V
V
V
F
P
---
V
S
V
H
Y
--
D
H
--
T
R
K
L
L
Q
S
K
F
S
T
G
---
I
Q
N
V
S
K
F
-
G
N
G
S
Y
T
G
E
V
S
A
E
I
A
K
D
L
N
I
E
Y
V
I
I
G
H
F
E
R
R
K
Y
F
H
E
T
D
E
D
V
R
E
K
L
Q
A
S
L
K
N
N
L
K
A
V
V
C
F
G
E
S
L
E
Q
R
E
Q
N
K
T
I
E
V
I
T
K
Q
V
K
A
F
V
D
L
I
--
D
N
F
D
N
-
V
I
L
V
Y
E
P
L
W
A
I
G
T
G
K
T
A
T
P
E
Q
A
Q
L
V
H
K
E
I
R
KIV
K
D
T
-
C
G
E
--
K
--
Q
A
-----
N
Q
I
R
----
I
L
Y
G
G
S
V
N
T
E
N
C
S
S
L
I
Q
Q
E
D
I
D
G
F
L
V
G
N
A
S
L
-
K
E
S
F
V
D
I
I
K
S
-----
86
PsiBlast_CBE
80.63
39%
-87
- C7 -
-
4YXG
3
TPIS_PLAFA
A:
[6-246]
--------
F
V
A
A
N
W
K
C
N
G
T
L
E
S
I
K
S
L
T
N
S
F
N
--
N
--
L
----
D
F
D
P
S
K
--
L
D
V
V
V
F
P
---
V
S
V
H
Y
--
D
H
--
T
R
K
L
L
Q
S
K
F
S
T
G
---
I
Q
N
V
S
K
F
-
G
N
G
S
Y
T
G
E
V
S
A
E
I
A
K
D
L
N
I
E
Y
V
I
I
G
H
Y
E
R
R
K
Y
F
H
E
T
D
E
D
V
R
E
K
L
Q
A
S
L
K
N
N
L
K
A
V
V
C
F
G
E
S
L
E
Q
R
E
Q
N
K
T
I
E
V
I
T
K
Q
V
K
A
F
V
D
L
I
--
D
N
F
D
N
-
V
I
L
V
Y
E
P
L
W
--------
T
P
E
Q
A
Q
L
V
H
K
E
I
R
K
I
V
K
D
T
-
C
G
E
--
K
--
Q
A
-----
N
Q
I
R
----
I
L
Y
G
G
S
V
N
T
E
N
C
S
S
L
I
Q
Q
E
D
I
D
G
F
L
V
G
N
A
S
L
-
K
E
S
F
V
D
I
I
K
S
-----
116
PsiBlast_CBE
80.25
39%
-77
- C7 -
-
4ZZ9
3
TPIS_PLAFA
A:
[6-246]
--------
F
V
A
A
N
W
K
C
N
G
T
L
E
S
I
K
S
L
T
N
S
F
N
--
N
--
L
----
D
F
D
P
S
K
--
L
D
V
V
V
F
P
---
V
S
V
H
Y
--
D
H
--
T
R
K
L
L
Q
S
K
F
S
T
G
---
I
Q
N
V
S
K
F
-
G
N
G
S
Y
S
G
E
V
S
A
E
I
A
K
D
L
N
I
E
Y
V
I
I
G
H
F
E
R
R
K
Y
F
H
E
T
D
E
D
V
R
E
K
L
Q
A
S
L
K
N
N
L
K
A
V
V
C
F
G
E
S
L
E
Q
R
E
Q
N
K
T
I
E
V
I
T
K
Q
V
K
A
F
V
D
L
I
--
D
N
F
D
N
-
V
I
L
V
Y
E
P
L
W
A
I
G
T
---
A
T
P
E
Q
A
Q
L
V
H
K
E
I
R
K
I
V
K
D
T
-
C
G
E
--
K
--
Q
A
-----
N
Q
I
R
----
I
L
Y
G
G
S
V
N
T
E
N
C
S
S
L
I
Q
Q
E
D
I
D
G
F
L
V
G
N
A
S
L
-
K
E
S
F
V
D
I
I
K
S
-----
67
PsiBlast_CBE
80.19
40%
-77
- C7 -
-
4YWI
5
TPIS_PLAFA
B:
[6-246]
--------
F
V
A
A
N
W
K
C
N
G
T
L
E
S
I
K
S
L
T
N
S
F
N
--
N
--
L
----
D
F
D
P
S
K
--
L
D
V
V
V
F
P
---
V
S
V
H
Y
--
D
H
--
T
R
K
L
L
Q
S
K
F
S
T
G
---
I
Q
N
V
S
K
F
-
G
N
G
S
Y
T
G
E
V
S
A
E
I
A
K
D
L
N
I
E
Y
V
I
I
G
H
S
E
R
R
K
Y
F
H
E
T
D
E
D
V
R
E
K
L
Q
A
S
L
K
N
N
L
K
A
V
V
C
F
G
E
S
L
E
Q
R
E
Q
N
K
T
I
E
V
I
T
K
Q
V
K
A
F
V
D
L
I
--
D
N
F
D
N
-
V
I
L
V
Y
E
P
V
W
A
I
G
--
K
T
A
T
P
E
Q
A
Q
L
V
H
K
E
I
R
K
I
V
K
D
T
-
C
G
E
--
K
--
Q
A
-----
N
Q
I
R
----
I
L
Y
G
G
S
V
N
T
E
N
C
S
S
L
I
Q
Q
E
D
I
D
G
F
L
V
G
N
A
S
L
-
K
E
S
F
V
D
I
I
K
S
-----
88
PsiBlast_CBE
79.83
39%
-71
- C7 -
-
2VFI
3
TPIS_PLAFA
A:
[6-246]
--------
F
V
A
A
N
W
K
C
N
G
T
L
E
S
I
K
S
L
T
N
S
F
N
--
N
--
L
----
D
F
D
P
S
K
--
L
D
V
V
V
F
P
---
V
S
V
H
Y
--
D
H
--
T
R
K
L
L
Q
S
K
F
S
T
G
---
I
Q
N
V
S
K
F
-
G
N
G
S
Y
T
G
E
V
S
A
E
I
A
K
D
L
N
I
E
Y
V
I
I
G
H
F
E
R
R
K
Y
F
H
E
T
D
E
D
V
R
E
K
L
Q
A
S
L
K
N
N
L
K
A
V
V
C
F
G
E
S
L
E
Q
R
E
Q
N
K
T
I
E
V
I
T
K
Q
V
K
A
F
V
D
L
I
--
D
N
F
D
N
-
V
I
L
V
Y
E
P
L
W
A
I
G
T
G
K
T
A
T
P
E
Q
A
Q
L
V
H
K
E
I
R
K
I
V
K
D
T
-
C
G
E
--
K
--
Q
A
-----
N
Q
I
R
----
I
L
Y
G
G
S
V
N
T
E
N
C
S
S
L
I
Q
Q
E
D
I
D
G
F
L
V
G
N
A
S
L
-
K
E
S
F
V
D
I
I
K
S
-----
121
PsiBlast_CBE
79.77
39%
-85
- C7 -
-
3PSW
2
TPIS_PLAFA
B:
[6-246]
--------
F
V
A
A
N
W
K
C
N
G
T
L
E
S
I
K
S
L
T
N
S
F
N
--
N
--
L
----
D
F
D
P
S
K
--
L
D
V
V
V
F
P
---
V
S
V
H
Y
--
D
H
--
T
R
K
L
L
Q
S
K
F
S
T
G
---
I
Q
N
V
S
K
F
-
G
N
G
S
Y
T
G
E
V
S
A
E
I
A
K
D
L
N
I
E
Y
V
I
I
G
H
F
Q
R
R
K
Y
F
H
E
T
D
E
D
V
R
E
K
L
Q
A
S
L
K
N
N
L
K
A
V
V
C
F
G
E
S
L
E
Q
R
E
Q
N
K
T
I
E
V
I
T
K
Q
V
K
A
F
V
D
L
I
--
D
N
F
D
N
-
V
I
L
V
Y
E
P
L
W
A
I
G
T
G
K
T
A
T
P
E
Q
A
Q
L
V
H
K
E
I
R
KIV
K
D
T
-
C
G
E
--
K
--
Q
A
-----
N
Q
I
R
----
I
L
Y
G
G
S
------
S
S
L
I
Q
Q
E
D
I
D
G
F
L
V
G
N
A
S
L
-
K
E
S
F
V
D
I
I
K
S
-----
109
PsiBlast_CBE
79.56
37%
-66
- C7 -
-
3UWV
2
TPIS_STAAR
A:
[7-258]
--
G
S
M
R
T
P
I
I
A
G
N
W
K
M
N
K
T
V
Q
E
A
K
D
F
V
N
A
L
P
--
T
--
L
P
D
S
K
E
V
E
S
V
I
--
C
----
A
P
----
A
I
Q
L
--
D
A
--
L
T
T
A
V
K
E
G
K
A
Q
G
L
E
I
G
A
Q
N
T
Y
F
E
D
N
G
A
F
T
G
E
T
S
P
V
A
L
A
D
L
G
V
K
Y
V
V
I
G
H
S
E
R
R
E
L
F
H
E
T
D
E
E
I
N
K
K
A
H
A
I
F
K
H
G
M
T
P
I
I
C
V
G
E
T
D
E
E
R
E
S
G
K
A
N
D
V
V
G
E
Q
V
K
K
A
V
A
G
L
S
E
D
Q
L
K
S
-
V
V
I
A
Y
E
P
I
W
A
I
G
T
G
K
S
S
T
S
E
D
A
N
E
M
C
A
F
V
R
---
Q
T
I
-
A
D
L
--
S
--
S
K
--
E
--
V
S
E
A
T
R
--
I
Q
Y
G
G
S
V
K
P
N
N
I
K
E
Y
M
A
Q
T
D
I
D
G
A
L
V
G
G
A
S
L
K
V
E
D
F
V
Q
L
L
E
------
107
PsiBlast_CBE
79.00
37%
-64
- C7 -
-
3UWW
2
TPIS_STAAR
A:
[8-258]
---
S
M
R
T
P
I
I
A
G
N
W
K
M
N
K
T
V
Q
E
A
K
D
F
V
N
A
L
P
--
T
--
L
P
D
S
K
E
V
E
S
V
I
--
C
----
A
P
----
A
I
Q
L
--
D
A
--
L
T
T
A
V
K
E
G
K
A
Q
G
L
E
I
G
A
Q
N
T
Y
F
E
D
N
G
A
F
T
G
E
T
S
P
V
A
L
A
D
L
G
V
K
Y
V
V
I
G
H
S
E
R
R
E
L
F
H
E
T
D
E
E
I
N
K
K
A
H
A
I
F
K
H
G
M
T
P
I
I
C
V
G
E
T
D
E
E
R
E
S
G
K
A
N
D
V
V
G
E
Q
V
K
K
A
V
A
G
L
S
E
D
Q
L
K
S
-
V
V
I
A
Y
E
P
I
W
A
I
G
T
G
K
S
S
T
S
E
D
A
N
E
M
C
A
F
V
R
---
Q
T
I
-
A
D
L
--
S
--
S
K
--
E
--
V
S
E
A
T
R
--
I
Q
Y
G
G
S
V
K
P
N
N
I
K
E
Y
M
A
Q
T
D
I
D
G
A
L
V
G
G
A
S
L
K
V
E
D
F
V
Q
L
L
E
------
89
PsiBlast_CBE
78.84
39%
-88
- C7 -
-
1O5X
1
TPIS_PLAFA
B:
[6-246]
--------
F
V
A
A
N
W
K
C
N
G
T
L
E
S
I
K
S
L
T
N
S
F
N
--
N
--
L
----
D
F
D
P
S
K
--
L
D
V
V
V
F
P
---
V
S
V
H
Y
--
D
H
--
T
R
K
L
L
Q
S
K
F
S
T
G
---
I
Q
N
V
S
K
F
-
G
N
G
S
Y
T
G
E
V
S
A
E
I
A
K
D
L
N
I
E
Y
V
I
I
G
H
F
E
R
R
K
Y
F
H
E
T
D
E
D
V
R
E
K
L
Q
A
S
L
K
N
N
L
K
A
V
V
C
F
G
E
S
L
E
Q
R
E
Q
N
K
T
I
E
V
I
T
K
Q
V
K
A
F
V
D
L
I
--
D
N
F
D
N
-
V
I
L
V
Y
E
P
L
W
A
I
G
T
G
K
T
A
T
P
E
Q
A
Q
L
V
H
K
E
I
R
KIV
K
D
T
-
C
G
E
--
K
--
Q
A
-----
N
Q
I
R
----
I
L
Y
G
G
-------
S
S
L
I
Q
Q
E
D
I
D
G
F
L
V
G
N
A
S
L
-
K
E
S
F
V
D
I
I
K
S
-----
108
PsiBlast_CBE
78.77
37%
-64
- C7 -
-
3UWV
2
TPIS_STAAR
B:
[8-258]
---
S
M
R
T
P
I
I
A
G
N
W
K
M
N
K
T
V
Q
E
A
K
D
F
V
N
A
L
P
--
T
--
L
P
D
S
K
E
V
E
S
V
I
--
C
----
A
P
----
A
I
Q
L
--
D
A
--
L
T
T
A
V
K
E
G
K
A
Q
G
L
E
I
G
A
Q
N
T
Y
F
E
D
N
G
A
F
T
G
E
T
S
P
V
A
L
A
D
L
G
V
K
Y
V
V
I
G
H
S
E
R
R
E
L
F
H
E
T
D
E
E
I
N
K
K
A
H
A
I
F
K
H
G
M
T
P
I
I
C
V
G
E
T
D
E
E
R
E
S
G
K
A
N
D
V
V
G
E
Q
V
K
K
A
V
A
G
L
S
E
D
Q
L
K
S
-
V
V
I
A
Y
E
P
I
W
A
I
G
T
G
K
S
S
T
S
E
D
A
N
E
M
C
A
F
V
R
---
Q
T
I
-
A
D
L
--
S
--
S
K
--
E
--
V
S
E
A
T
R
--
I
Q
Y
G
G
S
V
K
P
N
N
I
K
E
Y
M
A
Q
T
D
I
D
G
A
L
V
G
G
A
S
L
K
V
E
D
F
V
Q
L
L
E
------
140
HHSearch
78.66
37%
-89
- C7 -
-
3YPI
1
TPIS_YEAST
B:
[1-246]
----
A
R
T
F
F
V
G
G
N
F
K
L
N
G
S
K
Q
S
I
K
E
I
V
E
R
L
N
--
T
--
A
S
-----
I
P
E
N
--
V
E
V
V
I
C
P
---
P
A
T
Y
L
--
D
Y
--
S
V
S
L
V
K
--
K
P
Q
V
T
V
G
A
Q
N
A
Y
-
L
K
A
S
G
A
F
T
G
E
N
S
V
D
Q
I
K
D
V
G
A
K
W
V
I
L
G
Q
S
E
R
R
S
Y
F
H
E
D
D
K
F
I
A
D
K
T
K
F
A
L
G
Q
G
V
G
V
I
L
C
I
G
E
T
L
E
E
K
K
A
G
K
T
L
D
V
V
E
R
Q
L
N
A
V
L
E
E
V
--
K
D
W
T
-
N
V
V
V
A
Y
E
P
V
W
A
I
G
T
G
L
A
A
T
P
E
D
A
Q
D
I
H
A
S
I
R
---
K
F
L
-
A
S
K
--
L
GD
K
A
--
A
--
S
E
L
R
----
I
L
Y
G
G
S
A
N
G
S
N
A
V
T
F
K
D
K
A
D
V
D
G
F
L
V
G
G
A
S
L
K
P
E
-
F
V
D
I
I
N
S
R
----
110
PsiBlast_CBE
78.65
37%
-64
- C7 -
-
3UWU
1
TPIS_STAAR
B:
[9-258]
----
M
R
T
P
I
I
A
G
N
W
K
M
N
K
T
V
Q
E
A
K
D
F
V
N
A
L
P
--
T
--
L
P
D
S
K
E
V
E
S
V
I
--
C
----
A
P
----
A
I
Q
L
--
D
A
--
L
T
T
A
V
K
E
G
K
A
Q
G
L
E
I
G
A
Q
N
T
Y
F
E
D
N
G
A
F
T
G
E
T
S
P
V
A
L
A
D
L
G
V
K
Y
V
V
I
G
H
S
E
R
R
E
L
F
H
E
T
D
E
E
I
N
K
K
A
H
A
I
F
K
H
G
M
T
P
I
I
C
V
G
E
T
D
E
E
R
E
S
G
K
A
N
D
V
V
G
E
Q
V
K
K
A
V
A
G
L
S
E
D
Q
L
K
S
-
V
V
I
A
Y
E
P
I
W
A
I
G
T
G
K
S
S
T
S
E
D
A
N
E
M
C
A
F
V
R
---
Q
T
I
-
A
D
L
--
S
--
S
K
--
E
--
V
S
E
A
TR--
I
Q
Y
G
G
S
V
K
P
N
N
I
K
E
Y
M
A
Q
T
D
I
D
G
A
L
V
G
G
A
S
L
K
V
E
D
F
V
Q
L
L
E
------
105
PsiBlast_CBE
78.47
37%
-64
- C7 -
-
3UWZ
1
TPIS_STAAR
A:
[8-258]
---
S
M
R
T
P
I
I
A
G
N
W
K
M
N
K
T
V
Q
E
A
K
D
F
V
N
A
L
P
--
T
--
L
P
D
S
K
E
V
E
S
V
I
--
C
----
A
P
----
A
I
Q
L
--
D
A
--
L
T
T
A
V
K
E
G
K
A
Q
G
L
E
I
G
A
Q
N
T
Y
F
E
D
N
G
A
F
T
G
E
T
S
P
V
A
L
A
D
L
G
V
K
Y
V
V
I
G
H
S
E
R
R
E
L
F
H
E
T
D
E
E
I
N
K
K
A
H
A
I
F
K
H
G
M
T
P
I
I
C
V
G
E
T
D
E
E
R
E
S
G
K
A
N
D
V
V
G
E
Q
V
K
K
A
V
A
G
L
S
E
D
Q
L
K
S
-
V
V
I
A
Y
E
P
I
W
A
I
G
T
G
K
S
S
T
S
E
D
A
N
E
M
C
A
F
V
R
---
Q
T
I
-
A
D
L
--
S
--
S
K
--
E
--
V
S
E
A
T
R
--
I
Q
Y
G
G
S
V
K
P
N
N
I
K
E
Y
M
A
Q
T
D
I
D
G
A
L
V
G
G
A
S
L
K
V
E
D
F
V
Q
L
L
E
------
106
PsiBlast_CBE
78.37
37%
-62
- C7 -
-
3UWW
2
TPIS_STAAR
B:
[10-258]
-----
R
T
P
I
I
A
G
N
W
K
M
N
K
T
V
Q
E
A
K
D
F
V
N
A
L
P
--
T
--
L
P
D
S
K
E
V
E
S
V
I
--
C
----
A
P
----
A
I
Q
L
--
D
A
--
L
T
T
A
V
K
E
G
K
A
Q
G
L
E
I
G
A
Q
N
T
Y
F
E
D
N
G
A
F
T
G
E
T
S
P
V
A
L
A
D
L
G
V
K
Y
V
V
I
G
H
S
E
R
R
E
L
F
H
E
T
D
E
E
I
N
K
K
A
H
A
I
F
K
H
G
M
T
P
I
I
C
V
G
E
T
D
E
E
R
E
S
G
K
A
N
D
V
V
G
E
Q
V
K
K
A
V
A
G
L
S
E
D
Q
L
K
S
-
V
V
I
A
Y
E
P
I
W
A
I
G
T
G
K
S
S
T
S
E
D
A
N
E
M
C
A
F
V
R
---
Q
T
I
-
A
D
L
--
S
--
S
K
--
E
--
V
S
E
A
T
R
--
I
Q
Y
G
G
S
V
K
P
N
N
I
K
E
Y
M
A
Q
T
D
I
D
G
A
L
V
G
G
A
S
L
K
V
E
D
F
V
Q
L
L
E
------
111
PsiBlast_CBE
78.33
37%
-62
- C7 -
-
3UWU
2
TPIS_STAAR
A:
[9-258]
----
M
R
T
P
I
I
A
G
N
W
K
M
N
K
T
V
Q
E
A
K
D
F
V
N
A
L
P
--
T
--
L
P
D
S
K
E
V
E
S
V
I
--
C
----
A
P
----
A
I
Q
L
--
D
A
--
L
T
T
A
V
K
E
G
K
A
Q
G
L
E
I
G
A
Q
N
T
Y
F
E
D
N
G
A
F
T
G
E
T
S
P
V
A
L
A
D
L
G
V
K
Y
V
V
I
G
H
S
E
R
R
E
L
F
H
E
T
D
E
E
I
N
K
K
A
H
A
I
F
K
H
G
M
T
P
I
I
C
V
G
E
T
D
E
E
R
E
S
G
K
A
N
D
V
V
G
E
Q
V
K
K
A
V
A
G
L
S
E
D
Q
L
K
S
-
V
V
I
A
Y
E
P
I
W
A
I
G
T
G
K
S
S
T
S
E
D
A
N
E
M
C
A
F
V
R
---
Q
T
I
-
A
D
L
--
S
--
S
K
--
E
--
V
S
E
A
T
R
--
I
Q
Y
G
G
S
V
K
P
N
N
I
K
E
Y
M
A
Q
T
D
I
D
G
A
L
V
G
G
A
S
L
K
V
E
D
F
V
Q
L
L
E
------
24
PsiBlast_CBE
77.99
46%
-12
- C7 -
-
2I9E
2
?
B:
[7-245]
---------
V
G
G
N
W
K
M
N
G
D
K
K
Q
I
N
E
I
I
G
-
F
L
--
K
--
S
G
P
L
N
Q
--
D
T
E
--
V
V
V
G
V
P
A
---
I
Y
L
E
L
VR
T
C
--
V
P
A
S
I
G
V
A
A
Q
N
C
Y
K
V
P
K
--------
G
A
F
T
G
E
I
S
P
A
M
I
K
D
V
G
A
D
W
V
I
L
G
H
S
E
R
R
Q
I
F
G
E
S
D
E
L
I
A
E
K
V
C
H
A
L
E
S
G
L
K
V
I
A
C
I
G
E
T
L
E
E
R
E
A
G
K
T
E
E
V
V
F
R
Q
T
K
A
I
A
A
K
V
N
--
D
W
S
N
-
V
V
I
A
Y
E
P
V
W
A
I
G
T
G
K
T
A
T
P
Q
Q
A
Q
D
V
H
K
A
L
R
---
Q
W
I
-
C
E
N
--
I
--
D
A
KV
G
--
N
S
I
R
----
I
Q
Y
G
G
S
V
T
A
A
N
C
K
E
L
A
S
Q
P
D
I
D
G
F
L
V
G
G
A
S
L
K
-
P
E
F
V
D
I
I
N
A
-----
125
PsiBlast_CBE
77.73
39%
-82
- C7 -
-
5BMX
2
TPIS_PLAFA
D:
[6-246]
--------
F
V
A
A
N
W
K
C
N
G
T
L
E
S
I
K
S
L
T
N
S
F
N
--
N
--
L
----
D
F
D
P
S
K
--
L
D
V
V
V
F
P
---
V
S
V
H
Y
--
D
H
--
T
R
K
L
L
Q
S
K
F
S
T
G
---
I
Q
N
V
S
K
F
-
G
N
G
S
Y
N
G
E
V
S
A
E
I
A
K
D
L
N
I
E
Y
V
I
I
G
H
F
E
R
R
K
Y
F
H
E
T
D
E
D
V
R
E
K
L
Q
A
S
L
K
N
N
L
K
A
V
V
C
F
G
E
S
L
E
Q
R
E
Q
-
K
T
I
E
V
I
T
K
Q
V
K
A
F
V
D
L
I
--
D
N
F
D
N
-
V
I
L
V
Y
E
P
L
W
A
------
A
T
P
E
Q
A
Q
L
V
H
K
E
I
R
KIV
K
D
T
-
C
G
E
--
K
--
Q
A
-----
N
Q
I
R
----
I
L
Y
G
G
S
V
N
T
E
N
C
S
S
L
I
Q
Q
E
D
I
D
G
F
L
V
G
N
A
S
L
-
K
E
S
F
V
D
I
I
K
S
-----
104
PsiBlast_CBE
76.89
37%
-67
- C7 -
-
3UWZ
1
TPIS_STAAR
B:
[9-258]
----
M
R
T
P
I
I
A
G
N
W
K
M
N
K
T
V
Q
E
A
K
D
F
V
N
A
L
P
--
T
--
L
P
D
S
K
E
V
E
S
V
I
--
C
----
A
P
----
A
I
Q
L
--
D
A
--
L
T
T
A
V
K
E
G
K
A
Q
G
L
E
I
G
A
Q
N
T
Y
F
E
D
N
G
A
F
T
G
E
T
S
P
V
A
L
A
D
L
G
V
K
Y
V
V
I
G
H
S
E
R
R
E
L
F
H
E
T
D
E
E
I
N
K
K
A
H
A
I
F
K
H
G
M
T
P
I
I
C
V
G
E
T
D
E
E
R
E
S
G
K
A
N
D
V
V
G
E
Q
V
K
K
A
V
A
G
L
S
E
D
Q
L
K
S
-
V
V
I
A
Y
E
P
I
W
A
I
---
K
S
S
T
S
E
D
A
N
E
M
C
A
F
V
R
---
Q
T
I
-
A
D
L
--
S
--
S
K
--
E
--
V
S
E
A
T
R
--
I
Q
Y
G
G
S
V
K
P
N
N
I
K
E
Y
M
A
Q
T
D
I
D
G
A
L
V
G
G
A
S
L
K
V
E
D
F
V
Q
L
L
E
------
22
PsiBlast_CBE
76.49
46%
-12
- C7 -
-
2I9E
3
?
D:
[7-245]
---------
V
G
G
N
W
K
M
N
G
D
K
K
Q
I
N
E
I
I
G
-
F
L
--
K
--
S
G
P
L
N
Q
--
D
T
E
--
V
V
V
G
V
P
A
---
I
Y
L
E
L
VR
T
C
--
V
P
A
S
I
G
V
A
A
Q
N
C
Y
K
V
P
K
--------
G
A
F
T
G
E
I
S
P
A
M
I
K
D
V
G
A
D
W
V
I
L
G
H
S
E
R
R
Q
I
F
G
E
S
D
E
L
I
A
E
K
V
C
H
A
L
E
S
G
L
K
V
I
A
C
I
G
E
T
L
E
E
R
E
A
G
K
T
E
E
V
V
F
R
Q
T
K
A
I
A
A
K
V
N
--
D
W
S
N
-
V
V
I
A
Y
E
P
V
W
A
I
G
T
G
K
T
A
T
P
Q
Q
A
Q
D
V
H
K
A
L
R
---
Q
W
I
-
C
E
N
--
I
--
D
A
KV
G
--
N
S
I
R
----
I
Q
Y
G
G
S
V
T
A
A
N
C
K
E
L
A
S
Q
P
D
I
D
G
F
L
V
G
G
A
S
L
K
-
P
E
F
V
D
I
I
N
A
-----
103
PsiBlast_CBE
76.47
40%
-22
- C7 -
-
1SW3
1
TPIS_CHICK
A:
[7-246]
--------
F
V
G
G
N
W
K
M
N
G
D
K
K
S
L
G
E
L
I
------
H
--
T
L
N
G
A
K
L
S
A
D
T
--
E
V
V
C
G
A
P
SIY
L
D
F
A
R
--
Q
K
--
L
D
A
K
I
G
V
A
A
Q
N
C
Y
K
V
P
K
--------
G
A
F
T
G
E
I
S
P
A
M
I
K
D
I
G
A
A
W
V
I
L
G
H
S
E
R
R
H
V
F
G
E
S
D
E
L
I
G
Q
K
V
A
H
A
L
A
E
G
L
G
V
I
A
C
I
G
E
K
L
D
E
R
E
A
G
I
T
E
K
V
V
F
E
Q
T
K
A
I
A
D
N
V
--
K
D
W
-
S
K
V
V
L
A
Y
E
P
V
W
A
I
G
T
G
K
V
A
T
P
Q
Q
A
Q
E
V
H
E
K
L
R
---
G
W
L
K
S
H
V
--
S
--
D
A
V
-
A
--
Q
S
T
R
----
I
I
Y
G
G
S
V
T
G
G
N
C
K
E
L
A
S
Q
H
D
V
D
G
F
L
V
G
G
A
S
L
K
-
P
E
F
V
D
I
I
N
A
-----
102
PsiBlast_CBE
75.39
40%
-22
- C7 -
-
1SW3
1
TPIS_CHICK
B:
[7-246]
--------
F
V
G
G
N
W
K
M
N
G
D
K
K
S
L
G
E
L
I
------
H
--
T
L
N
G
A
K
L
S
A
D
T
--
E
V
V
C
G
A
P
SIY
L
D
F
A
R
--
Q
K
--
L
D
A
K
I
G
V
A
A
Q
N
C
Y
K
V
P
K
--------
G
A
F
T
G
E
I
S
P
A
M
I
K
D
I
G
A
A
W
V
I
L
G
H
S
E
R
R
H
V
F
G
E
S
D
E
L
I
G
Q
K
V
A
H
A
L
A
E
G
L
G
V
I
A
C
I
G
E
K
L
D
E
R
E
A
G
I
T
E
K
V
V
F
E
Q
T
K
A
I
A
D
N
V
--
K
D
W
-
S
K
V
V
L
A
Y
E
P
V
W
A
I
G
T
G
K
V
A
T
P
Q
Q
A
Q
E
V
H
E
K
L
R
---
G
W
L
K
S
H
V
--
S
--
D
A
V-
A
--
Q
S
T
R
----
I
I
Y
G
G
S
V
T
G
G
N
C
K
E
L
A
S
Q
H
D
V
D
G
F
L
V
G
G
A
S
L
K
-
P
E
F
V
D
I
I
N
A
-----
101
PsiBlast_CBE
74.88
40%
-23
- C7 -
-
1TPW
1
TPIS_CHICK
A:
[6-245]
--------
F
V
G
G
N
W
K
M
N
G
D
K
K
S
L
G
E
L
I
------
H
--
T
L
N
G
A
K
L
S
A
D
T
--
E
V
V
C
G
A
P
SIY
L
D
F
A
R
--
Q
K
--
L
D
A
K
I
G
V
A
A
Q
N
C
Y
K
V
P
K
--------
G
A
F
T
G
E
I
S
P
A
M
I
K
D
I
G
A
A
W
V
I
L
G
H
P
E
R
R
H
V
F
G
E
S
D
E
L
I
G
Q
K
V
A
H
A
L
A
E
G
L
G
V
I
A
C
I
G
E
K
L
D
E
R
E
A
G
I
T
E
K
V
V
F
E
Q
T
K
A
I
A
D
N
V
--
K
D
W
-
S
K
V
V
L
A
Y
E
P
V
W
A
I
G
T
G
K
T
A
T
P
Q
Q
A
Q
E
V
H
E
K
L
R
---
G
W
L
K
T
H
V
--
S
--
D
A
V
-
A
--
Q
S
T
R
----
I
I
Y
G
G
S
V
T
G
G
N
C
K
E
L
A
S
Q
H
D
V
D
G
F
L
V
G
G
A
S
L
K
-
P
E
F
V
D
I
I
N
A
-----
100
PsiBlast_CBE
74.38
40%
-20
- C7 -
-
1TPW
1
TPIS_CHICK
B:
[6-245]
--------
F
V
G
G
N
W
K
M
N
G
D
K
K
S
L
G
E
L
I
------
H
--
T
L
N
G
A
K
L
S
A
D
T
--
E
V
V
C
G
A
P
SIY
L
D
F
A
R
--
Q
K
--
L
D
A
K
I
G
V
A
A
Q
N
C
Y
K
V
P
K
--------
G
A
F
T
G
E
I
S
P
A
M
I
K
D
I
G
A
A
W
V
I
L
G
H
P
E
R
R
H
V
F
G
E
S
D
E
L
I
G
Q
K
V
A
H
A
L
A
E
G
L
G
V
I
A
C
I
G
E
K
L
D
E
R
E
A
G
I
T
E
K
V
V
F
E
Q
T
K
A
I
A
D
N
V
--
K
D
W
-
S
K
V
V
L
A
Y
E
P
V
W
A
I
G
T
G
K
T
A
T
P
Q
Q
A
Q
E
V
H
E
K
L
R
---
G
W
L
K
T
H
V
--
S
--
D
A
V-
A
--
Q
S
T
R
----
I
I
Y
G
G
S
V
T
G
G
N
C
K
E
L
A
S
Q
H
D
V
D
G
F
L
V
G
G
A
S
L
K
-
P
E
F
V
D
I
I
N
A
-----
75
PsiBlast_CBE
74.34
40%
-31
- C7 -
-
5EYW
1
?
A:
[8-247]
--------
F
V
G
G
N
W
K
M
N
G
D
K
A
A
I
D
G
I
I
S
F
M
K
--
T
GP
L
S
P
N
T
E
V
V
-------
V
G
C
P
Q
---
C
Y
L
M
Y
--
T
R
E
H
M
P
A
N
I
G
I
A
A
Q
N
C
Y
K
V
A
K
--------
G
A
F
T
G
E
I
S
P
A
M
V
K
D
C
G
C
E
W
V
I
L
G
H
S
E
R
R
N
V
F
G
E
P
D
Q
L
I
S
E
K
V
G
H
A
L
E
A
G
L
K
V
I
P
C
I
G
E
K
L
E
D
R
E
G
N
R
T
Q
E
V
V
F
A
Q
M
K
A
L
L
P
N
I
S
--
D
W
-
S
R
V
V
L
A
Y
E
P
V
W
A
I
G
T
G
K
T
A
S
P
E
Q
A
Q
E
V
H
A
D
L
R
---
Q
W
L
-
R
D
N
--
V
--
N
A
E
V
A
--
E
S
T
R
----
I
I
Y
G
G
S
V
S
A
G
N
C
Q
E
L
A
K
K
G
D
I
D
G
F
L
V
G
G
A
A
L
K
-
P
D
F
V
Q
I
I
N
A
-----
50
PsiBlast_CBE
74.30
40%
-3
- C7 -
-
4OWG
1
TPIS_RABIT
A:
[7-246]
--------
F
V
G
G
N
W
K
M
N
G
R
K
K
N
L
G
E
L
I
T
T
L
N
A
A
K
--
V
P
A
D
T
E
V
V
-----
C
A
P
P
T
A
Y
---
I
D
F
A
R
--
Q
K
--
L
D
P
K
I
A
V
A
A
Q
N
C
Y
K
V
T
N
--------
G
A
F
T
G
E
I
S
P
G
M
I
K
D
C
G
A
T
W
V
V
L
G
H
S
E
R
R
H
V
F
G
E
S
D
E
L
I
G
Q
K
V
A
H
A
L
S
E
G
L
G
V
I
A
C
I
G
E
K
L
D
E
R
E
A
G
I
T
E
K
V
V
F
E
Q
T
K
V
I
A
D
N
V
--
K
D
W
-
S
K
V
V
L
A
Y
E
P
V
W
A
I
G
T
G
K
T
A
T
P
Q
Q
A
Q
E
V
H
E
K
L
R
---
G
W
L
K
S
N
V
--
S
--
D
A
V
-
A
--
Q
S
T
R
----
I
I
Y
G
G
S
V
T
G
A
T
C
K
E
L
A
S
Q
P
D
V
D
G
F
L
V
G
G
A
S
L
K
-
P
E
F
V
D
I
I
N
A
-----
123
PsiBlast_CBE
74.26
40%
-17
- C7 -
-
1TPU
1
TPIS_CHICK
B:
[6-245]
--------
F
V
G
G
N
W
K
M
N
G
D
K
K
S
L
G
E
L
I
------
H
--
T
L
N
G
A
K
L
S
A
D
T
--
E
V
V
C
G
A
P
SIY
L
D
F
A
R
--
Q
K
--
L
D
A
K
I
G
V
A
A
Q
N
C
Y
K
V
P
K
--------
G
A
F
T
G
E
I
S
P
A
M
I
K
D
I
G
A
A
W
V
I
L
G
N
S
E
R
R
H
V
F
G
E
S
D
E
L
I
G
Q
K
V
A
H
A
L
A
E
G
L
G
V
I
A
C
I
G
E
K
L
D
E
R
E
A
G
I
T
E
K
V
V
F
E
Q
T
K
A
I
A
D
N
V
--
K
D
W
-
S
K
V
V
L
A
Y
E
P
V
W
A
I
G
T
G
K
T
A
T
P
Q
Q
A
Q
E
V
H
E
K
L
R
---
G
W
L
K
T
H
V
--
S
--
D
A
V-
A
--
Q
S
T
R
----
I
I
Y
G
G
S
V
T
G
G
N
C
K
E
L
A
S
Q
H
D
V
D
G
F
L
V
G
G
A
S
L
K
-
P
E
F
V
D
I
I
N
A
-----
124
PsiBlast_CBE
74.12
40%
-17
- C7 -
-
1TPU
1
TPIS_CHICK
A:
[6-245]
--------
F
V
G
G
N
W
K
M
N
G
D
K
K
S
L
G
E
L
I
------
H
--
T
L
N
G
A
K
L
S
A
D
T
--
E
V
V
C
G
A
P
SIY
L
D
F
A
R
--
Q
K
--
L
D
A
K
I
G
V
A
A
Q
N
C
Y
K
V
P
K
--------
G
A
F
T
G
E
I
S
P
A
M
I
K
D
I
G
A
A
W
V
I
L
G
N
S
E
R
R
H
V
F
G
E
S
D
E
L
I
G
Q
K
V
A
H
A
L
A
E
G
L
G
V
I
A
C
I
G
E
K
L
D
E
R
E
A
G
I
T
E
K
V
V
F
E
Q
T
K
A
I
A
D
N
V
--
K
D
W
-
S
K
V
V
L
A
Y
E
P
V
W
A
I
G
T
G
K
T
A
T
P
Q
Q
A
Q
E
V
H
E
K
L
R
---
G
W
L
K
T
H
V
--
S
--
D
A
V
-
A
--
Q
S
T
R
----
I
I
Y
G
G
S
V
T
G
G
N
C
K
E
L
A
S
Q
H
D
V
D
G
F
L
V
G
G
A
S
L
K
-
P
E
F
V
D
I
I
N
A
-----
49
PsiBlast_CBE
74.02
40%
-7
- C7 -
-
4OWG
1
TPIS_RABIT
B:
[7-246]
--------
F
V
G
G
N
W
K
M
N
G
R
K
K
N
L
G
E
L
I
T
T
L
N
AA
K
--
V
P
A
D
T
E
V
V
-----
C
A
P
P
T
A
Y
---
I
D
F
A
R
--
Q
K
--
L
D
P
K
I
A
V
A
A
Q
N
C
Y
K
V
T
N
--------
G
A
F
T
G
E
I
S
P
G
M
I
K
D
C
G
A
T
W
V
V
L
G
H
S
E
R
R
H
V
F
G
E
S
D
E
L
I
G
Q
K
V
A
H
A
L
S
E
G
L
G
V
I
A
C
I
G
E
K
L
D
E
R
E
A
G
I
T
E
K
V
V
F
E
Q
T
K
V
I
A
D
N
V
--
K
D
W
-
S
K
V
V
L
A
Y
E
P
V
W
A
I
G
T
G
K
T
A
T
P
Q
Q
A
Q
E
V
H
E
K
L
R
---
G
W
L
K
S
N
V
--
S
--
D
A
V-
A
--
Q
S
T
R
----
I
I
Y
G
G
S
V
T
G
A
T
C
K
E
L
A
S
Q
P
D
V
D
G
F
L
V
G
G
A
S
L
K
-
P
E
F
V
D
I
I
N
A
-----
74
PsiBlast_CBE
73.44
40%
-31
- C7 -
-
5EYW
1
?
B:
[8-247]
--------
F
V
G
G
N
W
K
M
N
G
D
K
A
A
I
D
G
I
I
S
F
M
K
--
T
GP
L
S
P
N
T
E
V
V
-------
V
G
C
P
Q
---
C
Y
L
M
Y
--
T
R
EH
M
P
A
N
I
G
I
A
A
Q
N
C
Y
K
V
A
K
--------
G
A
F
T
G
E
I
S
P
A
M
V
K
D
C
G
C
E
W
V
I
L
G
H
S
E
R
R
N
V
F
G
E
P
D
Q
L
I
S
E
K
V
G
H
A
L
E
A
G
L
K
V
I
P
C
I
G
E
K
L
E
D
R
E
G
N
R
T
Q
E
V
V
F
A
Q
M
K
A
L
L
P
N
I
S
--
D
W
-
S
R
V
V
L
A
Y
E
P
V
W
A
I
G
T
G
K
T
A
S
P
E
Q
A
Q
E
V
H
A
D
L
R
---
Q
W
L
-
R
D
N
--
V
--
N
A
EV
A
--
E
S
T
R
----
I
I
Y
G
G
S
V
S
A
G
N
C
Q
E
L
A
K
K
G
D
I
D
G
F
L
V
G
G
A
A
L
K
-
P
D
F
V
Q
I
I
N
A
-----
78
PsiBlast_CBE
70.35
40%
3
- C7 -
-
1HTI
1
TPIS_HUMAN
B:
[7-246]
--------
F
V
G
G
N
W
K
M
N
G
R
K
Q
S
L
G
E
L
I
---
G
--
T
--
L
N
A
A
K
V
P
A
D
T
E
VV
C
A
P
P
T
A
Y
---
I
D
F
A
R
--
Q
K
--
L
D
P
K
I
A
V
A
A
Q
N
C
Y
K
V
T
N
--------
G
A
F
T
G
E
I
S
P
G
M
I
K
D
C
G
A
T
W
V
V
L
G
H
S
E
R
R
H
V
F
G
E
S
D
E
L
I
G
Q
K
V
A
H
A
L
A
E
G
L
G
V
I
A
C
I
G
E
K
L
D
E
R
E
A
G
I
T
E
K
V
V
F
E
Q
T
K
V
I
A
D
N
V
--
K
D
W
-
S
K
V
V
L
A
Y
E
P
V
W
A
I
G
T
G
K
T
A
T
P
Q
Q
A
Q
E
V
H
E
K
L
R
---
G
W
L
K
S
N
V
--
S
--
D
A
V-
A
--
Q
S
T
R
----
I
I
Y
G
G
S
V
T
G
A
T
C
K
E
L
A
S
Q
P
D
V
D
G
F
L
V
G
G
A
S
L
K
-
P
E
F
V
D
I
I
N
A
-----