@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Wbm0158: (2015-11-28 )
MENLAYKLIKVTEAAALAAYKLVGLGDEKKADQVAVDAMRTVLNSMEINGTIVIGEGERDKAPMLYVGEKVGTGNGPEIDIAVDPLEGTTICAHYKQSAMSVLAAAKKGDFLHAPDIYMEKIAIGKDLPIGVVSLKNSVEKNFDNLAQAKKCEVNDLTVTILKRERHNNLILKIRKLGARVKLIDDGDIAAIVSLINGSHDIYIGIGGAPEGVLAAAALSSIGGQMEGRLIFDTHQSKERAKILNIDDLEKIYSIKDMVKGESVFIATGVTSGELVDGVKFGYNICSTSSLIMLHNKVIKLQTIQNLC
Atome Classification :
(20 SA)
---.........10........20..--......30........40........50........60...---..-----------...70..---.-.-----------..----..80........90...-..-...100.......110--........---------.120.......130.......140-....----.....150.....---..160.....---.-.----170-...-...-.-..180.......190-...--..--...200.--....--.--.210...-.-...-220.......230------...------------...------------.-------240.......250.......260-.-.-..-...270.......280.......290..--...--..300......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---MENL
A
Y
K
L
I
K
V
T
E
A
A
A
L
A
A
Y
K
L
V--GLGDEK
K
A
D
Q
V
A
V
D
A
M
R
T
V
L
NSMEIN
G
T
I
V
I
GEGERDKA
P
M
---
L
Y
-----------
V
G
E
KVGT---G-N-----------G
P
----
E
I
D
I
A
VDPLEGT
T
I
C
A
H
-
Y
K
-
Q
S
A
M
S
V
L
A
A
AKKGD----FLHA
P
D
I
Y
---------
M
E
K
IAIGKDLPI
G
V
V
S
L
K
N
S
V
E
---
K
N
F
D
----
N
L
A
Q
AKKCEVN
D
L
---
T
V
T
I
L
KRERH---N-
N
----
L
---
I
L
K
-
I
RK-L-G
A
R
V
K
L
IDD
G
D
I
A
A
--
I
V
S
--
L
I--NGSH
D
I
Y
--
I
GIG--G--AP
E
G
V
L
A
-
A
-
A
A
L
-
S
S
IGGQME
G
R
L
I
F
------DTH------------QSK------------E-------R
A
K
IL
N
I
D
D
L
E
K
I
Y
S
I
K
D
MVKGE-
S
-
V
-
F
I
-
A
TGVTS
G
E
L
V
D
G
V
K
F
G
Y
N
ICST
S
S
L
I
M
L--HN
K
--
V
I
K
L
Q
T
I
Q
NLC
19
HHSearch
96.44
41%
-106
- C5 -
3ROJ
21
FBSB_SYNY3
A:
[36-370]
---
D
S
T
L
G
L
E
I
I
E
V
V
E
Q
A
A
I
A
S
A
K
W
M
--
G
K
G
E
K
N
T
A
D
Q
V
A
V
E
A
M
R
E
R
M
N
K
I
H
M
R
G
R
I
V
I
G
E
G
E
R
D
D
A
P
M
---
L
Y
-----------
I
G
E
E
V
G
I
---
C
T
R
EDAKSFCNPDE
L
V
----
E
I
D
I
A
V
D
P
C
E
G
T
N
L
V
A
Y
-
G
Q
-
N
G
S
M
A
V
L
A
I
S
E
K
G
G
----
L
F
A
A
P
D
F
Y
---------
M
K
K
L
A
A
P
P
A
A
K
-
G
H
V
D
I
D
K
S
A
T
---
E
N
L
K
----
I
L
S
D
C
L
N
R
S
I
E
E
L
---
V
V
V
V
M
D
R
P
R
H
---
K
-
E
----
L
---
I
Q
E
-
I
R
N
-
A
-
G
A
R
V
R
L
I
S
D
G
D
V
S
A
--
A
I
S
C
A
F
S
--
G
T
N
I
H
A
L
--
M
G
I
G
--
A
--
A
P
E
G
V
I
S
-
A
-
A
A
M
-
R
C
L
G
G
H
F
Q
G
Q
L
I
Y
------
D
P
E
VVKTGLIGES
R
E
G
N
L
------------
E
-------
R
L
A
S
M
G
I
K
N
P
D
Q
V
Y
N
C
E
E
L
A
C
G
E
-
T
V
L
-
F
A
-
A
C
G
I
T
P
G
T
L
M
E
G
V
R
F
F
H
G
G
V
R
T
Q
S
L
V
I
S
--
S
Q
S
S
T
A
R
F
V
D
T
V
H
M
K
E
20
HHSearch
95.86
45%
-100
- C5 -
3BIG
2
GLPX_ECOLI
A:
[4-326]
---
R
R
E
L
A
I
E
F
S
R
V
T
E
S
A
A
L
A
G
Y
K
W
L
--
G
R
G
D
K
N
T
A
D
G
A
A
V
N
A
M
R
I
M
L
N
Q
V
N
I
D
G
T
I
V
I
G
E
G
E
I
A
E
A
P
M
---
L
Y
-----------
I
G
E
K
V
G
T
---
G
-
R
-----------
G
D
----
A
V
D
I
A
V
D
P
I
E
G
T
R
M
T
A
M
-
G
Q
-
A
N
A
L
A
V
L
A
V
G
D
K
G
C
----
F
L
N
A
P
D
M
Y
---------
M
E
K
L
I
V
G
P
G
A
K
-
G
T
I
D
L
N
L
P
L
A
---
D
N
L
R
----
N
V
A
A
A
L
G
K
P
L
S
E
L
---
T
V
T
I
L
A
K
P
R
H
---
D
-
A
----
V
---
I
A
E
-
M
Q
Q
-
L
-
G
V
R
V
F
A
I
P
D
G
D
V
A
A
--
S
I
L
T
C
M
P
--
D
S
E
V
D
V
L
--
Y
G
I
G
--
G
--
A
P
E
G
V
V
S
-
A
-
A
V
I
-
R
A
L
D
G
D
M
N
G
R
L
L
A
------
R
H
D
VKN
E
E
N
R
R
I
G
E
-
Q
E
L
------------
A
-------
R
C
K
A
M
G
I
-
E
A
G
K
V
L
R
L
G
D
M
A
R
S
D
-
N
V
I
-
F
S
-
A
T
G
I
T
K
G
D
L
L
E
G
I
S
R
K
G
N
I
A
T
T
E
T
L
L
I
R
--
G
K
S
T-
I
R
R
I
Q
S
I
H
Y
L
-
18
PsiBlast_CBE
94.36
40%
-103
- C5 -
3RPL
11
FBSB_SYNY3
A:
[38-354]
-----
T
L
G
L
E
I
I
E
V
V
E
Q
A
A
I
A
S
A
K
W
M
--
G
K
G
E
K
N
T
A
D
Q
V
A
V
E
A
M
R
E
R
M
N
K
I
H
M
R
G
R
I
V
I
G
E
G
E
R
D
D
A
P
M
---
L
Y
-----------
I
G
E
E
V
G
I
---
C
-
T
REDAKSFC---
N
P
DELV
E
I
D
I
A
V
D
P
C
E
G
T
N
L
V
A
Y
-
G
Q
-
N
G
S
M
A
V
L
A
I
S
E
K
G
G
----
L
F
A
A
P
D
F
Y
---------
M
K
K
L
A
-
A
P
P
A
A
K
G
H
V
D
I
D
K
S
A
T
---
E
N
L
K
----
I
L
S
D
C
L
N
R
S
I
E
E
L
---
V
V
V
V
M
D
R
P
R
H
---
K
-
E
----
L
---
I
Q
E
-
I
R
N
-
A
-
G
A
R
V
R
L
I
S
D
G
D
V
S
A
--
A
I
S
--
C
A
--
F
S
G
T
N
I
H
A
L
M
G
I
G
--
A
--
A
P
E
G
V
I
S
-
A
-
A
A
M
-
R
C
L
G
G
H
F
Q
G
Q
L
I
Y
------
D
P
E
------------
V
V
K
TGLIGES
R
E
G
N
L
E
-------
R
L
A
S
M
G
I
K
N
P
D
Q
V
Y
N
C
E
E
L
A
C
G
E
-
T
-
V
L
F
A
-
A
C
G
I
T
P
G
T
L
M
E
G
V
R
F
F
H
G
G
V
R
T
Q
S
L
V
I
S
--
S
Q
S
--
S
T
A
R
F
V
D
T
V
H
M
6
PsiBlast_PDB
94.22
40%
-106
- C5 -
3ROJ
21
FBSB_SYNY3
A:
[38-354]
-----
T
L
G
L
E
I
I
E
V
V
E
Q
A
A
I
A
S
A
K
W
M
--
G
K
G
E
K
N
T
A
D
Q
V
A
V
E
A
M
R
E
R
M
N
K
I
H
M
R
G
R
I
V
I
G
E
G
E
R
D
D
A
P
M
---
L
Y
-----------
I
G
E
E
V
G
I
---
C
-
T
REDAKSFC---
N
P
DELV
E
I
D
I
A
V
D
P
C
E
G
T
N
L
V
A
Y
-
G
Q
-
N
G
S
M
A
V
L
A
I
S
E
K
G
G
----
L
F
A
A
P
D
F
Y
---------
M
K
K
L
A
-
A
P
P
A
A
K
G
H
V
D
I
D
K
S
A
T
---
E
N
L
K
----
I
L
S
D
C
L
N
R
S
I
E
E
L
---
V
V
V
V
M
D
R
P
R
H
---
K
-
E
----
L
---
I
Q
E
-
I
R
N
-
A
-
G
A
R
V
R
L
I
S
D
G
D
V
S
A
--
A
I
S
--
C
A
--
F
S
G
T
N
I
H
A
L
M
G
I
G
--
A
--
A
P
E
G
V
I
S
-
A
-
A
A
M
-
R
C
L
G
G
H
F
Q
G
Q
L
I
Y
------
D
P
E
------------
V
V
K
TGLIGES
R
E
G
N
L
E
-------
R
L
A
S
M
G
I
K
N
P
D
Q
V
Y
N
C
E
E
L
A
C
G
E
-
T
-
V
L
F
A
-
A
C
G
I
T
P
G
T
L
M
E
G
V
R
F
F
H
G
G
V
R
T
Q
S
L
V
I
S
--
S
Q
S
--
S
T
A
R
F
V
D
T
V
H
M
17
PsiBlast_CBE
93.83
40%
-102
- C5 -
3RPL
13
FBSB_SYNY3
C:
[38-354]
-----
T
L
G
L
E
I
I
E
V
V
E
Q
A
A
I
A
S
A
K
W
M
--
G
K
G
E
K
N
T
A
D
Q
V
A
V
E
A
M
R
E
R
M
N
K
I
H
M
R
G
R
I
V
I
G
E
G
E
R
D
D
A
P
M
---
L
Y
-----------
I
G
E
E
V
G
I
---
C
-
T
REDAKSFC---
N
P
DELV
E
I
D
I
A
V
D
P
C
E
G
T
N
L
V
A
Y
-
G
Q
-
N
G
S
M
A
V
L
A
I
S
E
K
G
G
----
L
F
A
A
P
D
F
Y
---------
M
K
K
L
A
-
A
P
P
A
A
K
G
H
V
D
I
D
K
S
A
T
---
E
N
L
K
----
I
L
S
D
C
L
N
R
S
I
E
E
L
---
V
V
V
V
M
D
R
P
R
H
---
K
-
E
----
L
---
I
Q
E
-
I
R
N
-
A
-
G
A
R
V
R
L
I
S
D
G
D
V
S
A
--
A
I
S
--
C
A
--
F
S
G
T
N
I
H
AL
M
G
I
G
--
A
--
A
P
E
G
V
I
S
-
A
-
A
A
M
-
R
C
L
G
G
H
F
Q
G
Q
L
I
Y
------
D
P
E
------------
V
V
K
TGLIGESREGNL
E
-------
R
L
A
S
M
G
I
K
N
P
D
Q
V
Y
N
C
E
E
L
A
C
G
E
-
T
-
V
L
F
A
-
A
C
G
I
T
P
G
T
L
M
E
G
V
R
F
F
H
G
G
V
R
T
Q
S
L
V
I
S
--
S
Q
S
--
S
T
A
R
F
V
D
T
V
H
M
40
Fugue
93.80
45%
-105
- C5 -
1NI9
2
GLPX_ECOLI
A:
[1-327]
GHM
R
R
E
L
A
I
E
F
S
R
V
T
E
S
A
A
L
A
G
Y
K
W
L
--
G
R
G
D
K
N
T
A
D
G
A
A
V
N
A
M
R
I
M
L
N
Q
V
N
I
D
G
T
I
V
I
G
E
G
E
---
A
P
M
---
L
Y
-----------
I
G
E
K
V
G
T
---
G
-
R
-----------
G
D
----
A
V
D
I
A
V
D
P
I
E
G
T
-------
Q
-
A
N
A
L
A
V
L
A
V
G
D
K
G
C
----
F
L
N
A
P
D
M
Y
---------
M
E
K
L
I
V
G
P
G
A
K
-
G
T
I
D
L
N
L
P
L
A
---
D
N
L
R
----
N
V
A
A
A
L
G
K
P
L
S
E
L
---
T
V
T
I
L
A
K
--
H
---
D
-
A
----
V
---
I
A
E
-
M
Q
Q
-
L
-
G
V
R
V
F
A
I
P
D
G
D
V
A
A
--
S
I
L
--
T
C
MP
D
S
E
V
D
V
L
--
Y
G
I
G
--
G
--
A
P
E
G
V
V
S
-
A
-
A
V
I
-
R
A
L
D
G
D
M
N
G
R
L
L
A
------
G
I
--------------------------------------------
E
A
G
K
V
L
R
L
G
D
M
A
R
S
D
N
V
-
I
-
F
S
-
A
T
G
I
T
K
G
D
L
L
E
G
I
S
R
K
G
N
I
A
T
T
E
T
L
L
I
R
GK
S
R
T
--
I
R
R
I
Q
S
I
H
Y
L
D
7
PsiBlast_PDB
93.80
40%
-103
- C5 -
3RPL
10
FBSB_SYNY3
B:
[38-354]
-----
T
L
G
L
E
I
I
E
V
V
E
Q
A
A
I
A
S
A
K
W
M
--
G
K
G
E
K
N
T
A
D
Q
V
A
V
E
A
M
R
E
R
M
N
K
I
H
M
R
G
R
I
V
I
G
E
G
E
R
D
D
A
P
M
---
L
Y
-----------
I
G
E
E
V
G
I
---
C
-
T
REDAKSFC---
N
P
DELV
E
I
D
I
A
V
D
P
C
E
G
T
N
L
V
A
Y
-
G
Q
-
N
G
S
M
A
V
L
A
I
S
E
K
G
G
----
L
F
A
A
P
D
F
Y
---------
M
K
K
L
A
-
A
P
P
A
A
K
G
H
V
D
I
D
K
S
A
T
---
E
N
L
K
----
I
L
S
D
C
L
N
R
S
I
E
E
L
---
V
V
V
V
M
D
R
P
R
H
---
K
-
E
----
L
---
I
Q
E
-
I
R
N
-
A
-
G
A
R
V
R
L
I
S
D
G
D
V
S
A
--
A
I
S
--
C
A
--
F
S
G
T
N
I
H
A
L
M
G
I
G
--
A
--
A
P
E
G
V
I
S
-
A
-
A
A
M
-
R
C
L
G
G
H
F
Q
G
Q
L
I
Y
------
D
P
E
------------
V
V
K
TGLIGES
R
E
G
N
L
E
-------
R
L
A
S
M
G
I
K
N
P
D
Q
V
Y
N
C
E
E
L
A
C
G
E
-
T
-
V
L
F
A
-
A
C
G
I
T
P
G
T
L
M
E
G
V
R
F
F
H
G
G
V
R
T
Q
S
L
V
I
S
--
S
Q
S
--
S
T
A
R
F
V
D
T
V
H
M
3
PsiBlast_PDB
93.13
42%
-99
- C5 -
2R8T
4
GLPX_ECOLI
A:
[7-323]
------
L
A
I
E
F
S
R
V
T
E
S
A
A
L
A
G
Y
K
W
L
--
G
R
G
D
K
N
T
A
D
G
A
A
V
N
A
M
R
I
M
L
N
Q
V
N
I
D
G
T
I
V
I
G
E
G
E
I
A
E
A
P
M
---
L
Y
-----------
I
G
E
K
V
G
T
---
G
-
R
-----------
G
D
----
A
V
D
I
A
V
D
P
I
E
G
T
R
M
T
A
M
-
G
Q
-
A
N
A
L
A
V
L
A
V
G
D
K
G
C
----
F
L
N
A
P
D
M
Y
---------
M
E
K
L
I
V
G
P
G
A
K
-
G
T
I
D
L
N
L
P
L
A
---
D
N
L
R
----
N
V
A
A
A
L
G
K
P
L
S
E
L
---
T
V
T
I
L
A
K
P
R
H
---
D
-
A
----
V
---
I
A
E
-
M
Q
Q
-
L
-
G
V
R
V
F
A
I
P
D
G
D
V
A
A
S
I
L
T
C
--
M
P
--
D
S
E
V
D
V
L
--
Y
G
I
G
--
G
--
A
P
E
G
V
V
S
-
A
-
A
V
I
-
R
A
L
D
G
D
M
N
G
R
L
L
A
RHDVK----------------
E
N
R
------------
R
I
G
E
Q
E
L
A
R
C
K
A
M
G
I
-
E
A
G
K
V
L
R
L
G
D
M
A
R
S
D
-
N
-
V
I
F
S
-
A
T
G
I
T
K
G
D
L
L
E
G
I
S
R
K
G
N
I
A
T
T
E
T
L
-
L
I
--
R
G
K
--
S
R
T
I
R
R
I
Q
S
I
H
16
PsiBlast_CBE
92.85
40%
-102
- C5 -
3RPL
9
FBSB_SYNY3
D:
[38-354]
-----
T
L
G
L
E
I
I
E
V
V
E
Q
A
A
I
A
S
A
K
W
M
--
G
K
G
E
K
N
T
A
D
Q
V
A
V
E
A
M
R
E
R
M
N
K
I
H
M
R
G
R
I
V
I
G
E
G
E
R
D
D
A
P
M
---
L
Y
-----------
I
G
E
E
V
G
I
---
C
-
T
REDAKSFC---
N
P
DELV
E
I
D
I
A
V
D
P
C
E
G
T
N
L
V
A
Y
-
G
Q
-
N
G
S
M
A
V
L
A
I
S
E
K
G
G
----
L
F
A
A
P
D
F
Y
---------
M
K
K
L
A
-
A
P
P
A
A
K
G
H
V
D
I
D
K
S
A
T
---
E
N
L
K
----
I
L
S
D
C
L
N
R
S
I
E
E
L
---
V
V
V
V
M
D
R
P
R
H
---
K
-
E
----
L
---
I
Q
E
-
I
R
N
-
A
-
G
A
R
V
R
L
I
S
D
G
D
V
S
A
--
A
I
S
--
C
A
--
F
S
G
T
N
I
H
AL
M
G
I
G
--
A
--
A
P
E
G
V
I
S
-
A
-
A
A
M
-
R
C
L
G
G
H
F
Q
G
Q
L
I
Y
------
D
P
E
------------
V
V
K
TGLIGESREGNL
E
-------
R
L
A
S
M
G
I
K
N
P
D
Q
V
Y
N
C
E
E
L
A
C
G
E
-
T
-
V
L
F
A
-
A
C
G
I
T
P
G
T
L
M
E
G
V
R
F
F
H
G
G
V
R
T
Q
S
L
V
I
S
--
S
Q
S
--
S
T
A
R
F
V
D
T
V
H
M
5
PsiBlast_PDB
91.59
42%
-95
- C5 -
3BIH
1
GLPX_ECOLI
A:
[7-323]
------
L
A
I
E
F
S
R
V
T
E
S
A
A
L
A
G
Y
K
W
L
--
G
R
G
D
K
N
T
A
D
G
A
A
V
N
A
M
R
I
M
L
N
Q
V
N
I
D
G
T
I
V
I
G
E
G
E
I
A
E
A
P
M
---
L
Y
-----------
I
G
E
K
V
G
T
---
G
-
R
-----------
G
D
----
A
V
D
I
A
V
D
P
I
E
G
T
R
M
T
A
M
-
G
Q
-
A
N
A
L
A
V
L
A
V
G
D
K
G
C
----
F
L
N
A
P
D
M
Y
---------
M
E
K
L
I
V
G
P
G
A
K
-
G
T
I
D
L
N
L
P
L
A
---
D
N
L
R
----
N
V
A
A
A
L
G
K
P
L
S
E
L
---
T
V
T
I
L
A
K
P
R
H
---
D
-
A
----
V
---
I
A
E
-
M
Q
Q
-
L
-
G
V
R
V
F
A
I
P
D
G
D
V
A
A
S
I
L
T
C
--
M
P
--
D
S
E
V
D
V
L
--
Y
G
I
G
--
G
--
A
P
E
G
V
V
S
-
A
-
A
V
I
-
R
A
L
D
G
D
M
N
G
R
L
L
A
RHDVK--
N
E
------------
E
N
R
------------
R
I
G
E
Q
E
L
A
R
C
K
A
M
G
I
-
E
A
G
K
V
L
R
L
G
D
M
A
R
S
D
-
N
-
V
I
F
S
-
A
T
G
I
T
K
G
D
L
L
E
G
I
S
R
K
G
N
I
A
T
T
E
T
L
-
L
I
--
R
G
K
--
S
R
T
I
R
R
I
Q
S
I
H
4
PsiBlast_PDB
91.05
42%
-97
- C5 -
3BIG
2
GLPX_ECOLI
A:
[7-323]
------
L
A
I
E
F
S
R
V
T
E
S
A
A
L
A
G
Y
K
W
L
--
G
R
G
D
K
N
T
A
D
G
A
A
V
N
A
M
R
I
M
L
N
Q
V
N
I
D
G
T
I
V
I
G
E
G
E
I
A
E
A
P
M
---
L
Y
-----------
I
G
E
K
V
G
T
---
G
-
R
-----------
G
D
----
A
V
D
I
A
V
D
P
I
E
G
T
R
M
T
A
M
-
G
Q
-
A
N
A
L
A
V
L
A
V
G
D
K
G
C
----
F
L
N
A
P
D
M
Y
---------
M
E
K
L
I
V
G
P
G
A
K
-
G
T
I
D
L
N
L
P
L
A
---
D
N
L
R
----
N
V
A
A
A
L
G
K
P
L
S
E
L
---
T
V
T
I
L
A
K
P
R
H
---
D
-
A
----
V
---
I
A
E
-
M
Q
Q
-
L
-
G
V
R
V
F
A
I
P
D
G
D
V
A
A
S
I
L
T
C
--
M
P
--
D
S
E
V
D
V
L
--
Y
G
I
G
--
G
--
A
P
E
G
V
V
S
-
A
-
A
V
I
-
R
A
L
D
G
D
M
N
G
R
L
L
A
RHDVK--
N
E
------------
E
N
R
------------
R
I
G
E
Q
E
L
A
R
C
K
A
M
G
I
-
E
A
G
K
V
L
R
L
G
D
M
A
R
S
D
-
N
-
V
I
F
S
-
A
T
G
I
T
K
G
D
L
L
E
G
I
S
R
K
G
N
I
A
T
T
E
T
L
-
L
I
--
R
G
K
--
S
-
T
I
R
R
I
Q
S
I
H
1
PsiBlast_PDB
90.92
43%
-98
- C5 -
1NI9
2
GLPX_ECOLI
A:
[7-323]
------
L
A
I
E
F
S
R
V
T
E
S
A
A
L
A
G
Y
K
W
L
--
G
R
G
D
K
N
T
A
D
G
A
A
V
N
A
M
R
I
M
L
N
Q
V
N
I
D
G
T
I
V
I
G
E
G
---
E
A
P
M
---
L
Y
-----------
I
G
E
K
V
G
T
---
G
-
R
-----------
G
D
----
A
V
D
I
A
V
D
P
I
E
G
T
-------
Q
-
A
N
A
L
A
V
L
A
V
G
D
K
G
C
----
F
L
N
A
P
D
M
Y
---------
M
E
K
L
I
V
G
P
G
A
K
-
G
T
I
D
L
N
L
P
L
A
---
D
N
L
R
----
N
V
A
A
A
L
G
K
P
L
S
E
L
---
T
V
T
I
L
A
K
--
H
---
D
-
A
----
V
---
I
A
E
-
M
Q
Q
-
L
-
G
V
R
V
F
A
I
P
D
G
D
V
A
A
S
I
L
T
C
--
M
P
--
D
S
E
V
D
V
L
--
Y
G
I
G
--
G
--
A
P
E
G
V
V
S
-
A
-
A
V
I
-
R
A
L
D
G
D
M
N
G
R
L
L
A
-------------------------------------------------
G
I
-
E
A
G
K
V
L
R
L
G
D
M
A
R
S
D
-
N
-
V
I
F
S
-
A
T
G
I
T
K
G
D
L
L
E
G
I
S
R
K
G
N
I
A
T
T
E
T
L
-
L
I
--
R
G
K
--
S
R
T
I
R
R
I
Q
S
I
H
2
PsiBlast_PDB
90.46
42%
-97
- C5 -
3D1R
5
GLPX_ECOLI
A:
[6-322]
------
L
A
I
E
F
S
R
V
T
E
S
A
A
L
A
G
Y
K
W
L
--
G
R
G
D
K
N
T
A
D
G
A
A
V
N
A
M
R
I
M
L
N
Q
V
N
I
D
G
T
I
V
I
G
E
G
E
I
A
E
A
P
M
---
L
Y
-----------
I
G
E
K
V
G
T
---
G
-
R
-----------
G
D
----
A
V
D
I
A
V
D
P
I
E
G
T
R
M
T
A
M
-
G
Q
-
A
N
A
L
A
V
L
A
V
G
D
K
G
C
----
F
L
N
A
P
D
M
Y
---------
M
E
K
L
I
V
G
P
G
A
K
-
G
T
I
D
L
N
L
P
L
A
---
D
N
L
R
----
N
V
A
A
A
L
G
K
P
L
S
E
L
---
T
V
T
I
L
A
K
P
R
H
---
D
-
A
----
V
---
I
A
E
-
M
Q
Q
-
L
-
G
V
R
V
F
A
I
P
D
G
D
V
A
A
S
I
L
T
C
--
M
P
--
D
S
E
V
D
V
L
--
Y
G
I
G
--
G
--
A
P
E
G
V
V
S
-
A
-
A
V
I
-
R
A
L
D
G
D
M
N
G
R
L
L
A
RHDVKG
D
N
E
-------------
N
R
------------
R
I
G
E
Q
E
L
A
R
C
K
A
M
G
I
-
E
A
G
K
V
L
R
L
G
D
M
A
R
S
D
-
N
-
V
I
F
S
-
A
T
G
I
T
K
G
D
L
L
E
G
I
S
R
K
G
N
I
A
T
T
E
T
L
-
L
I
--
R
G
K
--
S
-
T
I
R
R
I
Q
S
I
H
30
HHSearch
42.11
21%
-62
- C5 -
1VDW
2
?
A:
[43-217]
--------------------------------
T
K
V
V
D
K
V
A
E
N
I
I
I
S
K
F
K
D
---
L
G
V
N
V
V
S
E
---------------------------
E
I
G
R
I--
D
-
Q
-----------
G
S
----
D
Y
T
V
V
V
D
P
L
D
G
S
Y
N
F
I
N
-
G
I
-
P
F
F
A
V
S
V
A
I
F
H
E
K
D
PI
Y
A
F
I
Y
E
P
--
I
---------
V
E
R
L
Y
E
G
I
P
G
K
-
G
S
-------
Y
---
L
N
G
E
----
K
I
K
V
R
E
L
A
E
K
--
P
---
S
I
S
F
Y
T
K
G
K
G
---
T
------------
K
-
I
I
D
----
K
V
K
R
T
R
T
L
G
A
I
A
L
--
E
L
A
Y
-
L
A
--
R
G
A
L
D
A
V
--
V
D
I
R
--
N
YL
R
P
T
D
I
A
A
G
V
-
V
I
A
-
R
E
A
G
A
I
V
K
D
L
D
G
K
------
D
V
E
------------
I
T
F
------------
S
-------
A
T
E
K
V
N
I
I
A
A
N
N
E
E
L
L
E
T
I
L
R
S
I
-
E
-
K
--------------------------------------------------
33
HHSearch
42.06
19%
-70
- C5 -
1JP4
6
BPNT1_RAT
A:
[47-263]
--------------------------------
Q
T
K
A
D
R
M
V
Q
M
S
I
C
S
S
L
S
R
K
-
F
P
K
L
T
I
I
G
E
E
D
L
P
--
E
V
DQE
L
I
EDGQS
E
E
I
L
K
Q
P
C
P
S
Q
Y
S
A--
I
-
K
-----------
E
E
----
D
L
V
V
W
V
D
P
V
D
G
T
K
E
Y
T
E
-
G
L
L
D
N
V
T
V
L
I
G
I
A
Y
E
G
K
AI
A
G
I
I
N
Q
P
-
Y
Y
NYQAGPDAV
L
G
R
T
I
W
G
V
L
G
L
-
G
A
F
----------
G
F
Q
------
L
K
E
A
---
P
A
G
K
H
----
I
I
T
T
T
R
S
H
S
---
N
-
K
----
L
---
V
T
D
C
I
A
A
-
M
-
N
-
P
D
N
V
L
R
V
G
G
A
G
N
--
K
I
I
Q
-
L
I
--
E
G
K
A
S
A
Y
--
V
F
A
S
PG
C
--
K
K
W
D
T
C
A
-
P
E
V
I
L
-
H
A
V
G
G
K
L
T
D
I
H
G
N
------
P
L
Q
------------
Y
D
K
------------
E
-------
V
K
H
M
N
S
A
G
V
L
A
A
L
R
N
Y
E
Y
Y
A
S
R
V
-
P
-
E
-
S
V
-
K
S
A
L
I
P
----------------------------------------
34
HHSearch
41.69
17%
-62
- C5 -
3B8B
7
?
A:
[59-264]
-------------------------------
P
L
T
I
A
D
R
K
A
H
E
A
I
V
A
I
L
N
E
T
--
P
-
F
P
V
L
S
E
E
G
K
-
M
D
Y
----------------------
A
V
---
R
-
R
-----------
G
W
----
D
T
L
W
I
V
D
P
L
D
G
T
K
E
F
I
K
-
R
N
-
G
E
F
T
V
N
I
A
L
V
Q
N
A
V
PV
M
G
V
I
Y
V
P
--
V
---------
K
K
E
L
Y
F
A
V
E
G
T
-
G
A
Y
-
K
C
S
G
I
V
GLE
D
E
G
V
T
L
Q
Q
M
I
E
K
S
E
R
M
P
L
A
D
A
R
D
H
F
I
A
V
A
S
R
S
H
L
---
T
-
P
E
T
E
T
Y
---
I
A
D
-
L
K
K
-
K
-
H
G
N
V
E
L
I
S
S
G
S
-
S
I
--
K
I
C
L
-
V
A
--
E
G
K
A
D
V
Y
--
P
R
F
A
P
-
T
--
M
E
W
D
T
A
A
-
G
-
H
A
I
A
R
A
A
G
M
E
V
Y
Q
A
G
K
E
------
E
P
L
------------
R
Y
N
------------
K
-------
E
D
L
L
N
P
W
F
I
V
E
A
K
R
E
--------------------------------------------------------------
31
HHSearch
39.57
13%
-60
- C5 -
2Q74
-
SUHB_MYCTU
A:
[54-250]
------------------------------
D
P
V
T
V
V
D
T
D
T
E
R
L
L
R
D
R
L
A
Q
L
-
R
P
G
D
P
I
L
G
E
E
G
----------------------------------------------------
R
V
T
W
V
L
D
P
I
D
G
T
V
N
F
V
Y
-
G
I
-
P
A
Y
A
V
S
I
G
A
Q
V
G
G
I
TV
A
G
A
V
A
D
V
--
A
---------
A
R
T
V
Y
S
A
A
T
G
L
-
G
A
H
----------
L
T
D
E
R
G
R
H
V
L
R
C
T
G
V
D
E
L
S
M
A
---
L
L
G
-
T
G
F
G
Y
S
VRC
R
-
E
----
K
---
Q
A
E
L
L
A
H
-
V
V
P
L
V
R
D
V
R
R
I
G
S
A
A
L
--
D
L
C
M
-
V
A
--
A
G
R
L
D
A
Y
--
Y
E
H
G
--
V
--
Q
V
W
D
C
A
A
-
G
A
L
I
A
-
A
E
A
G
A
R
V
L
L
S
A
G
L
------
V
V
V
------------
A
A
A
------------
P
-------
G
I
A
D
E
L
L
A
A
L
Q
R
F
N
G
L
E
------------------------------------------------------------
41
Fugue
37.69
13%
-42
- C5 -
1DK4
4
BSUHB_METJA
A:
[1-252]
--------
M
K
W
D
E
I
G
K
N
I
A
K
E
I
E
K
E
I
LP
Y
F
G
R
K
D
K
S
Y
V
V
G
T
S
P
S
G
D
E
T
E
I
F
D
K
I
S
E
D
I
A
L
K
Y
L
K
S
L
N
V
N
---
I
V
-----------
S
E
E
L
G
V
I
---
D
-
N
-----------
S
S
----
E
W
T
V
V
I
D
P
I
D
G
S
F
N
F
I
N
G
I
P
-
F
F
A
F
C
F
G
V
F
K
-------------------------------
N
N
E
P
Y
Y
G
L
T
Y
E
--
F
L
T
---
K
S
F
Y
----
E
A
Y
K
G
K
G
A
Y
L
N
G
R
---
K
I
K
V
K
D
F
N
P
N
---
N
-
I
----
V
---
I
S
Y
-
Y
P
S
----------
K
K
I
D
L
E
K
--
L
R
N
--
K
V
--
K
R
V
R
---------------
I
F
G
A
F
G
-
L
-
E
M
C
-
Y
V
A
K
G
T
L
D
A
V
F
------------------------------------------------------
D
V
R
P
K
V
R
A
V
D
I
A
S
S
Y
-
I
-
I
-
C
K
E
A
G
A
L
I
T
D
E
N
G
D
E
L
K
F
D
L
N
A
T
D
R
L
N
I
I
V
A
--
N
S
K
--
E
M
L
D
I
I
L
D
L
L
-
25
HHSearch
37.49
17%
-61
- C5 -
2QFL
2
SUHB_ECOLI
A:
[40-227]
--------------------------------
V
T
N
V
D
K
A
A
E
A
V
I
I
D
T
I
R
K
S
-
Y
P
Q
H
T
I
I
T
E
---------------------------
E
S
G
E
LE-
G
-
T
-----------
D
Q
----
D
V
Q
W
V
I
D
P
L
D
G
T
T
N
F
I
K
-
R
L
-
P
H
F
A
V
S
I
A
V
R
I
K
G
R
TE
V
A
V
V
Y
D
P
--
M
---------
R
N
E
L
F
T
A
T
R
G
Q
-
G
A
-------
Q
---
L
N
G
Y
----
R
L
R
G
S
T
A
R
D
L
D
G
T
---
I
L
A
-
T
G
F
P
F
K
---
A
K
Q
----
Y
A
T
T
Y
I
N
I
V
G
K
L
F
-
N
E
C
A
D
F
R
A
T
G
S
A
A
L
--
D
L
A
Y
-
V
A
--
A
G
R
V
D
G
F
--
F
E
I
G
--
L
--
R
P
W
D
F
A
A
G
E
-
L
L
V
-
R
E
A
G
G
I
V
S
D
F
T
G
G
------
H
N
Y
------------
M
L
T
------------
G
-------
N
I
V
A
G
N
P
R
V
V
K
A
M
L
A
N
M
R
D
E
L
S
-------------------------------------------------------
21
HHSearch
36.96
14%
-57
- C5 -
3T0J
5
?
A:
[46-232]
--------------------------------
V
T
N
V
D
K
A
T
E
D
F
I
F
D
T
I
L
E
T
-
Y
P
N
H
Q
V
L
G
E
---------------------------
E
G
H
G
HDI
D
-
T
-----------
S
K
----
G
T
V
W
V
V
D
P
I
D
G
T
L
N
F
V
H
-
Q
Q
-
E
N
F
A
I
S
I
G
I
Y
I
D
G
K
PY
A
G
F
V
Y
D
V
--
M
---------
A
D
V
L
Y
H
A
K
V
G
E
-
G
A
-------
Y
---
R
G
S
Q
----
P
L
K
P
L
N
D
S
N
L
R
Q
S
---
I
I
G
I
-
N
P
N
W
L
T
--
K
-
P
----
I
---
L
G
E
I
F
K
E
I
V
-
N
D
S
R
S
A
R
A
Y
G
S
A
A
L
--
E
I
V
S
-
V
A
--
T
G
N
L
E
A
Y
--
M
T
P
R
--
L
--
Q
P
W
D
F
A
G
G
L
-
V
I
L
-
Y
E
V
N
G
Q
A
S
N
L
L
G
E
------
P
L
T
------------
I
S
G
------------
P
-------
N
S
I
L
V
G
N
R
G
L
H
Q
E
I
S
N
D
Y
L
E
P
H
H
-
D
-
A
-
L
I
-
Q
L
H
E
Q
R
F
K
R
-------------------------------------